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Ulrike Seifert

Research Profile

Chemicals & Drugs

Physiology

Antigen Presentation

Anatomy

Disorders

Hepatitis C

Genes & Molecular Sequences

Amino Acid Sequences

Living Beings

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Publications

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Frédéric Ebstein; Peter-M Kloetzel; Orhan Aktas; Ulrike Kuckelkorn; Nicole Lange; Timour Prozorovski; Friederike Schröter; Ulrike Seifert; Antje Voigt; Annika Warnatsch; Elke Krüger
Immunoproteasomes are important for proteostasis in immune responses.
Frédéric Ebstein; Peter-Michael Kloetzel; Elke Krüger; Ulrike Seifert
Emerging roles of immunoproteasomes beyond MHC class I antigen processing.
Sabrina Urban; Fang Zhao; Kathrin Textoris-Taube; Helga Bernhard; Sandrine Cadel; Tanja Dannenberg; Frédéric Ebstein; Thierry Foulon; Anne Halenius; Peter Henklein; Katharina Janek; Jan H Kessler; Ferry Ossendorp; Annette Paschen; Julia Paschke; Barbara Reimann; Dirk Schadendorf; Christin Seifert; Ulrike Seifert
The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases.

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All Publications

2013: Frédéric Ebstein; Peter-M Kloetzel; Orhan Aktas; Ulrike Kuckelkorn; Nicole Lange; Timour Prozorovski; Friederike Schröter; Ulrike Seifert; Antje Voigt; Annika Warnatsch; Elke Krüger
Immunoproteasomes are important for proteostasis in immune responses.
Cell 2013;152(5):935-7.
2012: Frédéric Ebstein; Peter-Michael Kloetzel; Elke Krüger; Ulrike Seifert
Emerging roles of immunoproteasomes beyond MHC class I antigen processing.
Cellular and molecular life sciences : CMLS 2012;69(15):2543-58.
2012: Sabrina Urban; Fang Zhao; Kathrin Textoris-Taube; Helga Bernhard; Sandrine Cadel; Tanja Dannenberg; Frédéric Ebstein; Thierry Foulon; Anne Halenius; Peter Henklein; Katharina Janek; Jan H Kessler; Ferry Ossendorp; Annette Paschen; Julia Paschke; Barbara Reimann; Dirk Schadendorf; Christin Seifert; Ulrike Seifert
The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):529-38.
2010: Ulrike Seifert; Lukasz P Bialy; Frédéric Ebstein; Dawadschargal Bech-Otschir; Antje Voigt; Friederike Schröter; Timour Prozorovski; Nicole Lange; Janos Steffen; Melanie Rieger; Ulrike Kuckelkorn; Orhan Aktas; Peter-M Kloetzel; Elke Krüger
Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress.
Cell 2010;142(4):613-24.
2009: Frédéric Ebstein; Nicole Lange; Sabrina Urban; Ulrike Seifert; Elke Krüger; Peter-M Kloetzel
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
The international journal of biochemistry & cell biology 2009;41(5):1205-15.
2008: Ulrike Seifert; Elke Krüger
Remodelling of the ubiquitin-proteasome system in response to interferons.
Biochemical Society transactions 2008;36(Pt 5):879-84.
2007: Eui-Cheol Shin; Ulrike Seifert; Sabrina Urban; Kim-Thuy Truong; Stephen M Feinstone; Charles M Rice; Peter-M Kloetzel; Barbara Rehermann
Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007;27(12):985-90.
2007: Kathrin Textoris-Taube; Peter Henklein; Sylvie Pollmann; Theresa Bergann; Hardy Weisshoff; Ulrike Seifert; Ilse Drung; Clemens Mügge; Alice J A M Sijts; Peter-M Kloetzel; Ulrike Kuckelkorn
The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation.
The Journal of biological chemistry 2007;282(17):12749-54.
2007: Antje Voigt; Ulrike Salzmann; Ulrike Seifert; Margitta Dathe; Alejandro Soza; Peter-M Kloetzel; Ulrike Kuckelkorn
20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein.
Biochemical and biophysical research communications 2007;355(2):549-54.
2006: Eui-Cheol Shin; Ulrike Seifert; Takanobu Kato; Charles M Rice; Stephen M Feinstone; Peter-M Kloetzel; Barbara Rehermann
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection.
The Journal of clinical investigation 2006;116(11):3006-14.
2006: Izabela Młynarczuk-Biały; Heike Roeckmann; Ulrike Kuckelkorn; Boris Schmidt; Sumaira Umbreen; Jakub Gołab; Antje Ludwig; Christina Montag; Lüder Wiebusch; Christian Hagemeier; Dirk Schadendorf; Peter-M Kloetzel; Ulrike Seifert
Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells.
Cancer research 2006;66(15):7598-605.
2005: Britta Strehl; Ulrike Seifert; Elke Krüger; Sylvia Heink; Ulrike Kuckelkorn; Peter-M Kloetzel
Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.
Immunological reviews 2005;207():19-30.
2005: Xiaohua Huang; Bettina K J Hetfeld; Ulrike Seifert; Thilo Kähne; Peter-M Kloetzel; Michael Naumann; Dawadschargal Bech-Otschir; Wolfgang Dubiel
Consequences of COP9 signalosome and 26S proteasome interaction.
The FEBS journal 2005;272(15):3909-17.
2004: Ulrike Seifert; Heike Liermann; Vito Racanelli; Anne Halenius; Manfred Wiese; Heiner Wedemeyer; Thomas Ruppert; Kay Rispeter; Peter Henklein; Alice J A M Sijts; Hartmut Hengel; Peter-M Kloetzel; Barbara Rehermann
Hepatitis C virus mutation affects proteasomal epitope processing.
The Journal of clinical investigation 2004;114(2):250-9.
2003: Ulrike Seifert; Concepción Marañón; Ayelet Shmueli; Jean-François Desoutter; Lisa Wesoloski; Katharina Janek; Peter Henklein; Susanne Diescher; Muriel Andrieu; Henri de la Salle; Toni Weinschenk; Hansjörg Schild; Diego Laderach; Anne Galy; Gaby Haas; Peter-M Kloetzel; Yuval Reiss; Anne Hosmalin
An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.
Nature immunology 2003;4(4):375-9.
2002: Xiaohua Huang; Ulrike Seifert; Ulrike Salzmann; Peter Henklein; Robert Preissner; Wolfgang Henke; Alice J Sijts; Peter-M Kloetzel; Wolfgang Dubiel
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Journal of molecular biology 2002;323(4):771-82.
2000: A Takaki; M Wiese; Geert Maertens; Erik Depla; Ulrike Seifert; A Liebetrau; J L Miller; Michael P Manns; Barbara Rehermann
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C.
Nature medicine 2000;6(5):578-82.
1998: K Klugewitz; Barbara Rehermann; Ulrike Seifert; Klaus H W Böker; M Stolte; Peter N Meier; Siegfried Wagner; Michael P Manns
A rare case of bloody diarrhea: thrombosis of the V. mesenterica inferior following laparoscopic cholecystectomy.
Zeitschrift für Gastroenterologie 1998;36(1):35-9.
1997: Barbara Rehermann; K Klugewitz; Ulrike Seifert; Klaus H W Böker; Siegfried Wagner; Michael P Manns
[Rare initial manifestation and differential diagnosis of primary sclerosing cholangitis].
Medizinische Klinik (Munich, Germany : 1983) 1997;92(7):452-6.
1996: Barbara Rehermann; Ulrike Seifert; Hans L Tillmann; G Michel; Klaus H W Böker; Rudolf Pichlmayr; Michael P Manns
Serological pattern of hepatitis C virus recurrence after liver transplantation.
Journal of hepatology 1996;24(1):15-20.