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Tin Sein

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Theodouli Stergiopoulou; THOMAS WALSH; Joseph Meletiadis; Paraskevi Papaioannidou; Tin Sein; Emmanuel Roilides
Synergistic interaction of the triple combination of amphotericin B, ciprofloxacin, and polymorphonuclear neutrophils against Aspergillus fumigatus.
Vishnu Chaturvedi; Rama Ramani; David Andes; Daniel J Diekema; Michael A Pfaller; Mahmoud A Ghannoum; Cindy Knapp; Shawn R Lockhart; Luis Ostrosky-Zeichner; THOMAS WALSH; Karen Marchillo; Shawn Messer; Amanda R Welshenbaugh; Cara Bastulli; Naureen Iqbal; Victor L Paetznick; Jose Rodriguez; Tin Sein
Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.
Vasilios Pyrgos; Diana Mickiene; Tin Sein; Margaret Cotton; Andrea Fransesconi; Isaac Mizrahi; Martha Donoghue; Nikkida Bundrant; Su-Young Kim; Matthew Hardwick; Shmuel Shoham; THOMAS WALSH
Effects of immunomodulatory and organism-associated molecules on the permeability of an in vitro blood-brain barrier model to amphotericin B and fluconazole.

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All Publications

2011: Theodouli Stergiopoulou; THOMAS WALSH; Joseph Meletiadis; Paraskevi Papaioannidou; Tin Sein; Emmanuel Roilides
Synergistic interaction of the triple combination of amphotericin B, ciprofloxacin, and polymorphonuclear neutrophils against Aspergillus fumigatus.
Antimicrobial agents and chemotherapy 2011;55(12):5923-9.
2011: Vishnu Chaturvedi; Rama Ramani; David Andes; Daniel J Diekema; Michael A Pfaller; Mahmoud A Ghannoum; Cindy Knapp; Shawn R Lockhart; Luis Ostrosky-Zeichner; THOMAS WALSH; Karen Marchillo; Shawn Messer; Amanda R Welshenbaugh; Cara Bastulli; Naureen Iqbal; Victor L Paetznick; Jose Rodriguez; Tin Sein
Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.
Antimicrobial agents and chemotherapy 2011;55(4):1543-8.
2010: Vasilios Pyrgos; Diana Mickiene; Tin Sein; Margaret Cotton; Andrea Fransesconi; Isaac Mizrahi; Martha Donoghue; Nikkida Bundrant; Su-Young Kim; Matthew Hardwick; Shmuel Shoham; THOMAS WALSH
Effects of immunomodulatory and organism-associated molecules on the permeability of an in vitro blood-brain barrier model to amphotericin B and fluconazole.
Antimicrobial agents and chemotherapy 2010;54(3):1305-10.
2009: Vidmantas Petraitis; Ruta Petraitiene; William W Hope; Joseph Meletiadis; Diana Mickiene; Johanna E Hughes; Margaret P Cotton; Theodouli Stergiopoulou; Miki Kasai; Andrea Francesconi; Robert L Schaufele; Tin Sein; Nilo A Avila; John Bacher; THOMAS WALSH
Combination therapy in treatment of experimental pulmonary aspergillosis: in vitro and in vivo correlations of the concentration- and dose- dependent interactions between anidulafungin and voriconazole by Bliss independence drug interaction analysis.
Antimicrobial agents and chemotherapy 2009;53(6):2382-91.
2009: Theodouli Stergiopoulou; Joseph Meletiadis; Tin Sein; Paraskevi Papaioannidou; Ioannis Tsiouris; Emmanuel Roilides; THOMAS WALSH
Comparative pharmacodynamic interaction analysis between ciprofloxacin, moxifloxacin and levofloxacin and antifungal agents against Candida albicans and Aspergillus fumigatus.
The Journal of antimicrobial chemotherapy 2009;63(2):343-8.
2008: Theodouli Stergiopoulou; Anthony J De Lucca; Joseph Meletiadis; Tin Sein; Stephen M Boue; Robert L Schaufele; Emmanuel Roilides; Mahmoud Ghannoum; THOMAS WALSH
In vitro activity of CAY-1, a saponin from Capsicum frutescens, against Microsporum and Trichophyton species.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2008;46(8):805-10.
2008: Miki Kasai; Susan M Harrington; Andrea Francesconi; Vidmantas Petraitis; Ruta Petraitiene; Mara G Beveridge; Tena A Knudsen; Jeffery Milanovich; Margaret P Cotton; Johanna Hughes; Robert L Schaufele; Tin Sein; John Bacher; Patrick R Murray; Dimitrios P Kontoyiannis; THOMAS WALSH
Detection of a molecular biomarker for zygomycetes by quantitative PCR assays of plasma, bronchoalveolar lavage, and lung tissue in a rabbit model of experimental pulmonary zygomycosis.
Journal of clinical microbiology 2008;46(11):3690-702.
2008: Randall Hayden; Stanley Pounds; Katherine M Knapp; Ruta Petraitiene; Robert L Schaufele; Tin Sein; THOMAS WALSH
Galactomannan antigenemia in pediatric oncology patients with invasive aspergillosis.
The Pediatric infectious disease journal 2008;27(9):815-9.
2008: Theodouli Stergiopoulou; Joseph Meletiadis; Tin Sein; Paraskevi Papaioannidou; Ioannis Tsiouris; Emmanuel Roilides; THOMAS WALSH
Isobolographic analysis of pharmacodynamic interactions between antifungal agents and ciprofloxacin against Candida albicans and Aspergillus fumigatus.
Antimicrobial agents and chemotherapy 2008;52(6):2196-204.
2008: Vishnu Chaturvedi; Rama Ramani; Mahmoud A Ghannoum; Scott B Killian; Nicole Holliday; Cindy Knapp; Luis Ostrosky-Zeichner; Shawn A Messer; Michael A Pfaller; Naureen Iqbal; Beth A Arthington-Skaggs; Jose A Vazquez; Tin Sein; John H Rex; THOMAS WALSH
Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei.
Antimicrobial agents and chemotherapy 2008;52(4):1500-2.
2008: Charalampos Antachopoulos; Joseph Meletiadis; Tin Sein; Emmanuel Roilides; THOMAS WALSH
Comparative in vitro pharmacodynamics of caspofungin, micafungin, and anidulafungin against germinated and nongerminated Aspergillus conidia.
Antimicrobial agents and chemotherapy 2008;52(1):321-8.
2007: Theoklis E Zaoutis; Emmanuel Roilides; Christine C Chiou; Wendy L Buchanan; Tena A Knudsen; Tatyana A Sarkisova; Robert L Schaufele; Michael Sein; Tin Sein; Priya A Prasad; Jaclyn H Chu; THOMAS WALSH
Zygomycosis in children: a systematic review and analysis of reported cases.
The Pediatric infectious disease journal 2007;26(8):723-7.
2007: Charalampos Antachopoulos; Joseph Meletiadis; Tin Sein; Emmanuel Roilides; THOMAS WALSH
Concentration-dependent effects of caspofungin on the metabolic activity of Aspergillus species.
Antimicrobial agents and chemotherapy 2007;51(3):881-7.
2007: William W Hope; Michael J Kruhlak; Caron A Lyman; Ruta Petraitiene; Vidmantas Petraitis; Andrea Francesconi; Miki Kasai; Diana Mickiene; Tin Sein; Joanne Peter; Amy M Kelaher; Johanna E Hughes; Margaret P Cotton; Catherine J Cotten; John Bacher; Sanjay Tripathi; Louis Bermudez; Timothy K Maugel; Patricia M Zerfas; John R Wingard; George L Drusano; THOMAS WALSH
Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal therapy.
The Journal of infectious diseases 2007;195(3):455-66.
2007: Charalampos Antachopoulos; Joseph Meletiadis; Tin Sein; Emmanuel Roilides; THOMAS WALSH
Use of high inoculum for early metabolic signalling and rapid susceptibility testing of Aspergillus species.
The Journal of antimicrobial chemotherapy 2007;59(2):230-7.
2006: Andreas H Groll; Caron A Lyman; Vidmantas Petraitis; Ruta Petraitiene; Derek Armstrong; Diana Mickiene; Raul M Alfaro; Robert L Schaufele; Tin Sein; John Bacher; THOMAS WALSH
Compartmentalized intrapulmonary pharmacokinetics of amphotericin B and its lipid formulations.
Antimicrobial agents and chemotherapy 2006;50(10):3418-23.
2006: Joseph Meletiadis; Vidmantas Petraitis; Ruta Petraitiene; Pengxin Lin; Theodouli Stergiopoulou; Amy M Kelaher; Tin Sein; Robert L Schaufele; John Bacher; THOMAS WALSH
Triazole-polyene antagonism in experimental invasive pulmonary aspergillosis: in vitro and in vivo correlation.
The Journal of infectious diseases 2006;194(7):1008-18.
2006: Charalampos Antachopoulos; Joseph Meletiadis; Emmanuel Roilides; Tin Sein; Deanna A Sutton; Brian L Wickes; Michael G Rinaldi; William G Merz; Yvonne R Shea; THOMAS WALSH
Relationship between metabolism and biomass of medically important zygomycetes.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2006;44(5):429-38.
2006: Vidmantas Petraitis; Ruta Petraitiene; Jeffrey Solomon; Amy M Kelaher; Heidi A Murray; Christine Mya-San; Avi K Bhandary; Tin Sein; Nilo A Avila; Algidas Basevicius; John Bacher; THOMAS WALSH
Multidimensional volumetric imaging of pulmonary infiltrates for measuring therapeutic response to antifungal therapy in experimental invasive pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 2006;50(4):1510-7.
2006: Charalampos Antachopoulos; Joseph Meletiadis; Emmanuel Roilides; Tin Sein; THOMAS WALSH
Rapid susceptibility testing of medically important zygomycetes by XTT assay.
Journal of clinical microbiology 2006;44(2):553-60.
2006: Miki Kasai; Andrea Francesconi; Ruta Petraitiene; Vidmantas Petraitis; Amy M Kelaher; Hee-Sup Kim; Joseph Meletiadis; Tin Sein; John Bacher; THOMAS WALSH
Use of quantitative real-time PCR to study the kinetics of extracellular DNA released from Candida albicans, with implications for diagnosis of invasive Candidiasis.
Journal of clinical microbiology 2006;44(1):143-50.
2005: Maureen M Roden; Theoklis E Zaoutis; Wendy L Buchanan; Tena A Knudsen; Tatyana A Sarkisova; Robert L Schaufele; Michael Sein; Tin Sein; Christine C Chiou; Jaclyn H Chu; Dimitrios P Kontoyiannis; THOMAS WALSH
Epidemiology and outcome of zygomycosis: a review of 929 reported cases.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(5):634-53.
2005: Hee Sup Kim; Eun Hwa Choi; Javed Khan; Emmanuel Roilides; Andrea Francesconi; Miki Kasai; Tin Sein; Robert L Schaufele; Kenichi Sakurai; Chang Gue Son; Braden T Greer; STEPHEN CHANOCK; Caron A Lyman; THOMAS WALSH
Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans.
Infection and immunity 2005;73(6):3714-24.
2005: Ruta Petraitiene; Vidmantas Petraitis; Amy M Kelaher; Alia A Sarafandi; Diana Mickiene; Andreas H Groll; Tin Sein; John Bacher; THOMAS WALSH
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
Antimicrobial agents and chemotherapy 2005;49(5):2084-92.
2005: Hisako Yamagishi; Deirdre H Fitzgerald; Tin Sein; THOMAS WALSH; Brian C O'Connell
Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans.
FEMS microbiology letters 2005;244(1):207-12.
2004: THOMAS WALSH; Shmuel Shoham; Ruta Petraitiene; Tin Sein; Robert L Schaufele; Amy M Kelaher; Heidi Murray; Christine Mya-San; John Bacher; Vidmantas Petraitis
Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction.
Journal of clinical microbiology 2004;42(10):4744-8.
2004: Vidmantas Petraitis; Ruta Petraitiene; Amy M Kelaher; Alia A Sarafandi; Tin Sein; Diana Mickiene; John Bacher; Andreas H Groll; THOMAS WALSH
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
Antimicrobial agents and chemotherapy 2004;48(10):3959-67.
2003: THOMAS WALSH; Vidmantas Petraitis; Ruta Petraitiene; Aida Field-Ridley; Deanna Sutton; Mahmoud Ghannoum; Tin Sein; Robert L Schaufele; Joanne Peter; John Bacher; Heather Casler; Derek Armstrong; Ana Espinel-Ingroff; Michael G Rinaldi; Caron A Lyman
Experimental pulmonary aspergillosis due to Aspergillus terreus: pathogenesis and treatment of an emerging fungal pathogen resistant to amphotericin B.
The Journal of infectious diseases 2003;188(2):305-19.
2003: Vidmantas Petraitis; Ruta Petraitiene; Alia A Sarafandi; Amy M Kelaher; Caron A Lyman; Heather E Casler; Tin Sein; Andreas H Groll; John Bacher; Nilo A Avila; THOMAS WALSH
Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin.
The Journal of infectious diseases 2003;187(12):1834-43.
2003: Emmanuel Roilides; Caron A Lyman; Tin Sein; Ruta Petraitiene; THOMAS WALSH
Macrophage colony-stimulating factor enhances phagocytosis and oxidative burst of mononuclear phagocytes against Penicillium marneffei conidia.
FEMS immunology and medical microbiology 2003;36(1-2):19-26.
2002: Emmanuel Roilides; Caron A Lyman; Joanna Filioti; Onome Akpogheneta; Tin Sein; Cristina Gil Lamaignere; Ruta Petraitiene; THOMAS WALSH
Amphotericin B formulations exert additive antifungal activity in combination with pulmonary alveolar macrophages and polymorphonuclear leukocytes against Aspergillus fumigatus.
Antimicrobial agents and chemotherapy 2002;46(6):1974-6.
2002: Vidmantas Petraitis; Ruta Petraitiene; Andreas H Groll; Kristin Roussillon; Melissa Hemmings; Caron A Lyman; Tin Sein; John Bacher; Ihor Bekersky; THOMAS WALSH
Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits.
Antimicrobial agents and chemotherapy 2002;46(6):1857-69.
2002: Ruta Petraitiene; Vidmantas Petraitis; Andreas H Groll; Tin Sein; Robert L Schaufele; Andrea Francesconi; John Bacher; Nilo A Avila; THOMAS WALSH
Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia.
Antimicrobial agents and chemotherapy 2002;46(1):12-23.
2001: Ruta Petraitiene; Vidmantas Petraitis; Andreas H Groll; Tin Sein; Stephen C Piscitelli; M Candelario; Aida Field-Ridley; Nilo A Avila; John Bacher; THOMAS WALSH
Antifungal activity and pharmacokinetics of posaconazole (SCH 56592) in treatment and prevention of experimental invasive pulmonary aspergillosis: correlation with galactomannan antigenemia.
Antimicrobial agents and chemotherapy 2001;45(3):857-69.
2001: Vidmantas Petraitis; Ruta Petraitiene; Andreas H Groll; Tin Sein; Robert L Schaufele; Caron A Lyman; Andrea Francesconi; John Bacher; Stephen C Piscitelli; THOMAS WALSH
Dosage-dependent antifungal efficacy of V-echinocandin (LY303366) against experimental fluconazole-resistant oropharyngeal and esophageal candidiasis.
Antimicrobial agents and chemotherapy 2001;45(2):471-9.
2001: Emmanuel Roilides; Tin Sein; Maureen M Roden; Robert L Schaufele; THOMAS WALSH
Elevated serum concentrations of interleukin-10 in nonneutropenic patients with invasive aspergillosis.
The Journal of infectious diseases 2001;183(3):518-20.
2000: THOMAS WALSH; A J Jackson; J W Lee; M Amantea; Tin Sein; John Bacher; Loren A Zech
Dose-dependent pharmacokinetics of amphotericin B lipid complex in rabbits.
Antimicrobial agents and chemotherapy 2000;44(8):2068-76.
2000: E Roilides; Caron A Lyman; Tin Sein; Corina Gonzalez; THOMAS WALSH
Antifungal activity of splenic, liver and pulmonary macrophages against Candida albicans and effects of macrophage colony-stimulating factor.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2000;38(2):161-8.
1999: Ruta Petraitiene; Vidmantas Petraitis; Andreas H Groll; M Candelario; Tin Sein; A Bell; Caron A Lyman; C L McMillian; John Bacher; THOMAS WALSH
Antifungal activity of LY303366, a novel echinocandin B, in experimental disseminated candidiasis in rabbits.
Antimicrobial agents and chemotherapy 1999;43(9):2148-55.
1998: Vidmantas Petraitis; Ruta Petraitiene; Andreas H Groll; A Bell; DP Callender; Tin Sein; Robert L Schaufele; C L McMillian; John Bacher; THOMAS WALSH
Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits.
Antimicrobial agents and chemotherapy 1998;42(11):2898-905.
1998: Andreas H Groll; Tin Sein; Vidmantas Petraitis; Ruta Petraitiene; DP Callender; Corina Gonzalez; N Giri; John Bacher; Stephen C Piscitelli; THOMAS WALSH
Compartmental pharmacokinetics and tissue drug distribution of the pradimicin derivative BMS 181184 in rabbits.
Antimicrobial agents and chemotherapy 1998;42(10):2700-5.
1998: Corina Gonzalez; Andreas H Groll; N Giri; D Shetty; I Al-Mohsen; Tin Sein; E Feuerstein; John Bacher; Stephen C Piscitelli; THOMAS WALSH
Antifungal activity of the pradimicin derivative BMS 181184 in the treatment of experimental pulmonary aspergillosis in persistently neutropenic rabbits.
Antimicrobial agents and chemotherapy 1998;42(9):2399-404.
1998: Emmanuel Roilides; Tin Sein; Robert L Schaufele; STEPHEN CHANOCK; THOMAS WALSH
Increased serum concentrations of interleukin-10 in patients with hepatosplenic candidiasis.
The Journal of infectious diseases 1998;178(2):589-92.
1995: Emmanuel Roilides; Tin Sein; A Holmes; STEPHEN CHANOCK; C Blake; PA Pizzo; THOMAS WALSH
Effects of macrophage colony-stimulating factor on antifungal activity of mononuclear phagocytes against Aspergillus fumigatus.
The Journal of infectious diseases 1995;172(4):1028-34.
1995: THOMAS WALSH; William G Merz; J W Lee; Robert L Schaufele; Tin Sein; P O Whitcomb; M Ruddel; W Burns; J R Wingard; A C Switchenko
Diagnosis and therapeutic monitoring of invasive candidiasis by rapid enzymatic detection of serum D-arabinitol.
The American journal of medicine 1995;99(2):164-72.
1994: Emmanuel Roilides; T Robinson; Tin Sein; PA Pizzo; THOMAS WALSH
In vitro and ex vivo effects of cyclosporin A on phagocytic host defenses against Aspergillus fumigatus.
Antimicrobial agents and chemotherapy 1994;38(12):2883-8.