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Yutaka Seino

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Islets of Langerhans

Living Beings

Disorders

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Japan

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Molecular Sequence Data

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TOP 3
Liu Xibao; Harada Norio; Yamane Shunsuke; Kitajima Lisa; Uchida Saeko; Hamasaki Akihiro; Mukai Eri; Toyoda Kentaro; Yamada Chizumi; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice.
Funakoshi Shogo; Fujimoto Shimpei; Hamasaki Akihiro; Fujiwara Hideya; Fujita Yoshihito; Ikeda Kaori; Hamamoto Yoshiyuki; Hosokawa Masaya; Seino Yutaka; Inagaki Nobuya
Analysis of factors influencing pancreatic beta-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure.
Yabe Daisuke; Kuroe Akira; Ohya Michihiro; Watanabe Koin; Kitatani Naomi; Oku Masayuki; Kurose Takeshi; Seino Yutaka
A case of fulminant type 1 diabetes mellitus with exocrine pancreatic insufficiency and enhanced glucagon response to meal ingestion.

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All Publications

2009: Liu Xibao; Harada Norio; Yamane Shunsuke; Kitajima Lisa; Uchida Saeko; Hamasaki Akihiro; Mukai Eri; Toyoda Kentaro; Yamada Chizumi; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice.
Life sciences 2009;84(25-26):876-81.
2008: Funakoshi Shogo; Fujimoto Shimpei; Hamasaki Akihiro; Fujiwara Hideya; Fujita Yoshihito; Ikeda Kaori; Hamamoto Yoshiyuki; Hosokawa Masaya; Seino Yutaka; Inagaki Nobuya
Analysis of factors influencing pancreatic beta-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure.
Diabetes research and clinical practice 2008;82(3):353-8.
2008: Yabe Daisuke; Kuroe Akira; Ohya Michihiro; Watanabe Koin; Kitatani Naomi; Oku Masayuki; Kurose Takeshi; Seino Yutaka
A case of fulminant type 1 diabetes mellitus with exocrine pancreatic insufficiency and enhanced glucagon response to meal ingestion.
Diabetes research and clinical practice 2008;82(2):e1-4.
2008: Naitoh Rei; Miyawaki Kazumasa; Harada Norio; Mizunoya Wataru; Toyoda Kentaro; Fushiki Tohru; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice.
Biochemical and biophysical research communications 2008;376(1):21-5.
2008: Harada Norio; Fukushima Mitsuo; Toyoda Kentaro; Mitsui Rie; Izuka Tomoyo; Taniguchi Ataru; Nakai Yoshikatsu; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Factors responsible for elevation of 1-h postchallenge plasma glucose levels in Japanese men.
Diabetes research and clinical practice 2008;81(3):284-9.
2008: Sassa Mariko; Yamada Yuichiro; Hosokawa Masaya; Fukuda Kazuhito; Fujimoto Shimpei; Toyoda Kentaro; Tsukiyama Katsushi; Seino Yutaka; Inagaki Nobuya
Glycemic instability in type 1 diabetic patients: Possible role of ketosis or ketoacidosis at onset of diabetes.
Diabetes research and clinical practice 2008;81(2):190-5.
2008: Kominato R; Fujimoto S; Mukai E; Nakamura Y; Nabe K; Shimodahira M; Nishi Y; Funakoshi S; Seino Y; Inagaki N
Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.
Diabetologia 2008;51(7):1226-35.
2008: Fujiwara Hideya; Hosokawa Masaya; Zhou Xiaorong; Fujimoto Shimpei; Fukuda Kazuhito; Toyoda Kentaro; Nishi Yuichi; Fujita Yoshihito; Yamada Kotaro; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Curcumin inhibits glucose production in isolated mice hepatocytes.
Diabetes research and clinical practice 2008;80(2):185-91.
2008: Yamada Kotaro; Hosokawa Masaya; Yamada Chizumi; Watanabe Rie; Fujimoto Shimpei; Fujiwara Hideya; Kunitomo Masaru; Miura Toshihiro; Kaneko Tetsuo; Tsuda Kinsuke; Seino Yutaka; Inagaki Nobuya
Dietary corosolic acid ameliorates obesity and hepatic steatosis in KK-Ay mice.
Biological & pharmaceutical bulletin 2008;31(4):651-5.
2008: Fujita Yoshihito; Fukushima Mitsuo; Suzuki Haruhiko; Taniguchi Ataru; Nakai Yoshikatsu; Kuroe Akira; Yasuda Koichiro; Hosokawa Masaya; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka
Short-term intensive glycemic control improves vibratory sensation in type 2 diabetes.
Diabetes research and clinical practice 2008;80(1):e16-9.
2008: Yamada Kotaro; Hosokawa Masaya; Fujimoto Shimpei; Fujiwara Hideya; Fujita Yoshihito; Harada Norio; Yamada Chizumi; Fukushima Mitsuo; Ueda Naoya; Kaneko Tetsuo; Matsuyama Futoshi; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Effect of corosolic acid on gluconeogenesis in rat liver.
Diabetes research and clinical practice 2008;80(1):48-55.
2008: Toyoda Kentaro; Okitsu Teru; Yamane Shunsuke; Uonaga Taeko; Liu Xibao; Harada Norio; Uemoto Shinji; Seino Yutaka; Inagaki Nobuya
GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis.
Biochemical and biophysical research communications 2008;367(4):793-8.
2008: Toyoda Kentaro; Fukushima Mitsuo; Mitsui Rie; Harada Norio; Suzuki Hidehiko; Takeda Tomomi; Taniguchi Ataru; Nakai Yoshikatsu; Kawakita Toshiko; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka
Factors responsible for age-related elevation in fasting plasma glucose: a cross-sectional study in Japanese men.
Metabolism: clinical and experimental 2008;57(2):299-303.
2008: Yamada Chizumi; Yamada Yuichiro; Tsukiyama Katsushi; Yamada Kotaro; Udagawa Nobuyuki; Takahashi Naoyuki; Tanaka Kiyoshi; Drucker Daniel J; Seino Yutaka; Inagaki Nobuya
The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.
Endocrinology 2008;149(2):574-9.
2008: Harada Norio; Yamada Yuichiro; Tsukiyama Katsushi; Yamada Chizumi; Nakamura Yasuhiko; Mukai Eri; Hamasaki Akihiro; Liu Xibao; Toyoda Kentaro; Seino Yutaka; Inagaki Nobuya
A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.
American journal of physiology. Endocrinology and metabolism 2008;294(1):E61-8.
2007: Ikeda Hiroki; Yong Qing; Kurose Takeshi; Todo Takeshi; Mizunoya Wataru; Fushiki Tohru; Seino Yutaka; Yamada Yuichiro
Clock gene defect disrupts light-dependency of autonomic nerve activity.
Biochemical and biophysical research communications 2007;364(3):457-63.
2007: Yamada Chizumi; Yamada Yuichiro; Tsukiyama Katsushi; Yamada Kotaro; Yamane Shunsuke; Harada Norio; Miyawaki Kazumasa; Seino Yutaka; Inagaki Nobuya
Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes.
Biochemical and biophysical research communications 2007;364(1):175-80.
2007: Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Kuroe Akira; Ohya Michihiro; Ohgushi Minako; Seino Yutaka
Factors responsible for the evolution of insulin resistance in Japanese type 2 diabetic patients: association with atherosclerosis.
Diabetes research and clinical practice 2007;77 Suppl 1():S213-9.
2007: Fujimoto Shimpei; Nabe Koichiro; Takehiro Mihoko; Shimodahira Makiko; Kajikawa Mariko; Takeda Tomomi; Mukai Eri; Inagaki Nobuya; Seino Yutaka
Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production.
Diabetes research and clinical practice 2007;77 Suppl 1():S2-10.
2007: Takahashi Akira; Nagashima Kazuaki; Hamasaki Akihiro; Kuwamura Naomitsu; Kawasaki Yukiko; Ikeda Hiroki; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka
Sulfonylurea and glinide reduce insulin content, functional expression of K(ATP) channels, and accelerate apoptotic beta-cell death in the chronic phase.
Diabetes research and clinical practice 2007;77(3):343-50.
2007: Kuroe Akira; Taniuguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Ohgushi Minako; Ohya Michihiro; Seino Yutaka
Early and late onset side effects of short-acting insulin analogue in seven Japanese diabetic patients.
Diabetes research and clinical practice 2007;77(3):412-3.
2007: Inada Akari; Arai Hidenori; Nagai Kojiro; Miyazaki Jun-ichi; Yamada Yuichiro; Seino Yutaka; Fukatsu Atsushi
Gender difference in ICER Igamma transgenic diabetic mouse.
Bioscience, biotechnology, and biochemistry 2007;71(8):1920-6.
2007: Taniguchi Ataru; Fukushima Mitsuo; Kuroe Akira; Sakaguchi Kenji; Hashimoto Hiroko; Yoshioka Ikuko; Kitatani Naomi; Tsuji Tomoko; Ohya Michihiro; Ohgushi Minako; Nagasaka Shoichiro; Isogai Okihisa; Nakai Yoshikatsu; Inagaki Nobuya; Seino Yutaka
Metabolic syndrome, insulin resistance, and atherosclerosis in Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2007;56(8):1099-103.
2007: Kitatani N; Taniguchi A; Fukushima M; Nakai Y; Nagasaka S; Ohgushi M; Ohya M; Kuroe A; Inagaki N; Seino Y
Association of serum resistin with TNF system activity in Japanese type 2 diabetic patients.
Diabetes & metabolism 2007;33(2):156-7.
2007: Ohgushi Minako; Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Kuroe Akira; Ohya Michihiro; Nagasaka Shoichiro; Taki Yoshiro; Yoshii Satoru; Matsumoto Kazunari; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka
Soluble tumor necrosis factor receptor 2 is independently associated with pulse wave velocity in nonobese Japanese patients with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2007;56(4):571-7.
2007: Nabeya D; Taniguchi A; Fukushima M; Nakai Y; Matsumoto K; Kuroe A; Ohgushi M; Ohya M; Nagasaka S; Inagaki N; Seino Y
Soluble vascular cell adhesion molecule-1 is independently associated with soluble tumor necrosis factor receptor 2 in Japanese type 2 diabetic patients.
Diabetes & metabolism 2007;33(1):81-2.
2007: Hamasaki Akihiro; Yamada Yuichiro; Kurose Takeshi; Ban Nobuhiro; Nagashima Kazuaki; Takahashi Akira; Fujimoto Shimpei; Shimono Dai; Fujiwara Michio; Toyokuni Shinya; Seino Yutaka; Inagaki Nobuya
Adult pancreatic islets require differential pax6 gene dosage.
Biochemical and biophysical research communications 2007;353(1):40-6.
2007: Yamada Kotaro; Hosokawa Masaya; Fujimoto Shimpei; Nagashima Kazuaki; Fukuda Kazuhito; Fujiwara Hideya; Ogawa Eiichi; Fujita Yoshihito; Ueda Naoya; Matsuyama Futoshi; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
The spontaneously diabetic Torii rat with gastroenteropathy.
Diabetes research and clinical practice 2007;75(2):127-34.
2007: Yanagawa Takiko; Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Nagasaka Shoichiro; Ohgushi Minako; Matsumoto Kazunari; Kuroe Akira; Ohya Michihiro; Seino Yutaka
Leptin, triglycerides, and interleukin 6 are independently associated with C-reactive protein in Japanese type 2 diabetic patients.
Diabetes research and clinical practice 2007;75(1):2-6.
2006: Yamada Chizumi; Nagashima Kazuaki; Takahashi Akira; Ueno Hiroyuki; Kawasaki Yukiko; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis.
European journal of pharmacology 2006;553(1-3):67-72.
2006: Yamada Yuichiro; Fukuda Kazuhito; Fujimoto Shimpei; Hosokawa Masaya; Tsukiyama Katsushi; Nagashima Kazuaki; Fukushima Mitsuo; Suzuki Haruhiko; Toyoda Kentaro; Sassa Mariko; Funakoshi Shogo; Inagaki Nobuya; Taniguchi Ataru; Sato T Shun; Matsumoto Shinichi; Tanaka Koichi; Seino Yutaka
SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes.
Diabetes research and clinical practice 2006;74(3):222-6.
2006: Nomura Y; Taniguchi A; Fukushima M; Nakai Y; Nishimura F; Kuroe A; Ohgushi M; Ohya M; Murayama Y; Seino Y
Soluble TNF receptor and periodontal disease in non-obese Japanese type 2 diabetic patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(10):688-9.
2006: Sassa Mariko; Fukuda Kazuhito; Fujimoto Shimpei; Toyoda Kentaro; Fujita Yoshihito; Matsumoto Shinichi; Okitsu Teru; Iwanaga Yasuhiro; Noguchi Hirofumi; Nagata Hideo; Yonekawa Yukihide; Ohara Takeshi; Okamoto Masahiko; Tanaka Koichi; Seino Yutaka; Inagaki Nobuya; Yamada Yuichiro
A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement.
Diabetes research and clinical practice 2006;73(3):235-40.
2006: Nishimura F; Taniguchi A; Yamaguchi-Morimoto M; Soga Y; Iwamoto Y; Kokeguchi S; Kuroe A; Fukushima M; Nakai Y; Seino Y
Periodontal infection and dyslipidemia in type 2 diabetics: association with increased HMG-CoA reductase expression.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(8):530-5.
2006: Fukushima M; Matsuyama F; Ueda N; Egawa K; Takemoto J; Kajimoto Y; Yonaha N; Miura T; Kaneko T; Nishi Y; Mitsui R; Fujita Y; Yamada Y; Seino Y
Effect of corosolic acid on postchallenge plasma glucose levels.
Diabetes research and clinical practice 2006;73(2):174-7.
2006: Tsukiyama Katsushi; Yamada Yuichiro; Yamada Chizumi; Harada Norio; Kawasaki Yukiko; Ogura Masahito; Bessho Kazuhisa; Li Minqi; Amizuka Norio; Sato Masahiro; Udagawa Nobuyuki; Takahashi Naoyuki; Tanaka Kiyoshi; Oiso Yutaka; Seino Yutaka
Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion.
Molecular endocrinology (Baltimore, Md.) 2006;20(7):1644-51.
2006: Ohgushi Minako; Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Kuroe Akira; Ohya Michihiro; Seino Yutaka
Soluble tumor necrosis factor receptor 2 is independently associated with brachial-ankle pulse-wave velocity in nonobese Japanese type 2 diabetic patients.
Diabetes care 2006;29(6):1459-60.
2006: Nabe Koichiro; Fujimoto Shimpei; Shimodahira Makiko; Kominato Rieko; Nishi Yuichi; Funakoshi Shogo; Mukai Eri; Yamada Yuichiro; Seino Yutaka; Inagaki Nobuya
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.
Endocrinology 2006;147(6):2717-27.
2006: Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Ohgushi Minako; Kuroe Akira; Ohya Michihiro; Seino Yutaka
Soluble tumor necrosis factor receptor 1 is strongly and independently associated with serum homocysteine in nonobese Japanese type 2 diabetic patients.
Diabetes care 2006;29(4):949-50.
2006: Taniguchi Ataru; Fukushima Mitsuo; Ohya Michihiro; Nakai Yoshikatsu; Yoshii Satoru; Nagasaka Shoichiro; Matsumoto Kazunari; Taki Yoshiro; Kuroe Akira; Nishimura Fusanori; Seino Yutaka
Interleukin 6, adiponectin, leptin, and insulin resistance in nonobese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2006;55(2):258-62.
2006: Mitsui Rie; Fukushima Mitsuo; Nishi Yuichi; Ueda Naoya; Suzuki Haruhiko; Taniguchi Ataru; Nakai Yoshikatsu; Kawakita Toshiko; Kurose Takeshi; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka
Factors responsible for deteriorating glucose tolerance in newly diagnosed type 2 diabetes in Japanese men.
Metabolism: clinical and experimental 2006;55(1):53-8.
2005: Suzuki Hidehiko; Fukushima Mitsuo; Okamoto Shigeru; Takahashi Osamu; Shimbo Takuro; Kurose Takeshi; Yamada Yuichiro; Inagaki Nobuya; Seino Yutaka; Fukui Tsuguya
Effects of thorough mastication on postprandial plasma glucose concentrations in nonobese Japanese subjects.
Metabolism: clinical and experimental 2005;54(12):1593-9.
2005: Kawasaki Y; Taniguchi A; Fukushima M; Nakai Y; Kuroe A; Ohya M; Nagasaka S; Yamada Y; Inagaki N; Seino Y
Soluble TNF receptors and albuminuria in non-obese Japanese type 2 diabetic patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(10):617-21.
2005: Ohya Michihiro; Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Kawasaki Yukiko; Nagasaka Shoichiro; Kuroe Akira; Taki Yoshiro; Yoshii Satoru; Hosokawa Masaya; Inagaki Nobuya; Seino Yutaka
Three measures of tumor necrosis factor alpha activity and insulin resistance in nonobese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2005;54(10):1297-301.
2005: Nishi Yuichi; Fukushima Mitsuo; Suzuki Haruhiko; Mitsui Rie; Ueda Naoya; Taniguchi Ataru; Nakai Yoshikatsu; Kawakita Toshiko; Kurose Takeshi; Seino Yutaka; Yamada Yuichiro
Insulin secretion and insulin sensitivity in Japanese subjects with impaired fasting glucose and isolated fasting hyperglycemia.
Diabetes research and clinical practice 2005;70(1):46-52.
2005: Zhou Heying; Yamada Yuichiro; Tsukiyama Katsushi; Miyawaki Kazumasa; Hosokawa Masaya; Nagashima Kazuaki; Toyoda Kentaro; Naitoh Rei; Mizunoya Wataru; Fushiki Tohru; Kadowaki Takashi; Seino Yutaka
Gastric inhibitory polypeptide modulates adiposity and fat oxidation under diminished insulin action.
Biochemical and biophysical research communications 2005;335(3):937-42.
2005: Shimono Dai; Fujimoto Shimpei; Mukai Eri; Takehiro Mihoko; Nabe Koichiro; Radu Razvan Gheorghe; Shimodahira Makiko; Kominato Rieko; Aramaki Yo; Nishi Yuichi; Funakoshi Shogo; Yamada Yuichiro; Seino Yutaka
ATP enhances exocytosis of insulin secretory granules in pancreatic islets under Ca2+-depleted condition.
Diabetes research and clinical practice 2005;69(3):216-23.
2005: Fukuda Kazuhito; Inagaki Nobuya; Seino Yutaka
[Pancreatic polypeptide]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():521-3.
2005: Inada Akari; Nagai Kojiro; Arai Hidenori; Miyazaki Jun-ichi; Nomura Keiko; Kanamori Hiroshi; Toyokuni Shinya; Yamada Yuichiro; Bonner-Weir Susan; Weir Gordon C; Fukatsu Atsushi; Seino Yutaka
Establishment of a diabetic mouse model with progressive diabetic nephropathy.
The American journal of pathology 2005;167(2):327-36.
2005: Ueno Hiroyuki; Yamada Yuichiro; Watanabe Rie; Mukai Eri; Hosokawa Masaya; Takahashi Akira; Hamasaki Akihiro; Fujiwara Hideya; Toyokuni Shinya; Yamaguchi Masahiro; Takeda Jun; Seino Yutaka
Nestin-positive cells in adult pancreas express amylase and endocrine precursor Cells.
Pancreas 2005;31(2):126-31.
2005: Taniguchi Ataru; Fukushima Mitsuo; Nakai Yoshikatsu; Kuroe Akira; Yamano Gen; Yanagawa Takiko; Ohgushi Minako; Ohya Michihiro; Yoshii Satoru; Taki Yoshiro; Seino Yutaka
Soluble E-selectin, leptin, triglycerides, and insulin resistance in nonobese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2005;54(3):376-80.
2005: Ogura Masahito; Seino Yutaka
[Diet therapy for impaired glucose tolerance]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 2():503-8.
2005: Nishi Yuichi; Yamada Yuichiro; Fukushima Mitsuo; Seino Yutaka
[Insulin secretion and insulin sensitivity in subjects with impaired fasting glucose]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 2():151-4.
2005: Takehiro Mihoko; Fujimoto Shimpei; Shimodahira Makiko; Shimono Dai; Mukai Eri; Nabe Koichiro; Radu Razvan Gheorghe; Kominato Rieko; Aramaki Yo; Seino Yutaka; Yamada Yuichiro
Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E372-80.
2005: Radu Razvan Gheorghe; Fujimoto Shimpei; Mukai Eri; Takehiro Mihoko; Shimono Dai; Nabe Koichiro; Shimodahira Makiko; Kominato Rieko; Aramaki Yo; Nishi Yuichi; Funakoshi Shogo; Yamada Yuichiro; Seino Yutaka
Tacrolimus suppresses glucose-induced insulin release from pancreatic islets by reducing glucokinase activity.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E365-71.
2004: Nagashima Kazuaki; Takahashi Akira; Ikeda Hiroki; Hamasaki Akihiro; Kuwamura Naomitsu; Yamada Yuichiro; Seino Yutaka
Sulfonylurea and non-sulfonylurea hypoglycemic agents: pharmachological properties and tissue selectivity.
Diabetes research and clinical practice 2004;66 Suppl 1():S75-8.
2004: Fukushima Mitsuo; Suzuki Haruhiko; Seino Yutaka
Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes.
Diabetes research and clinical practice 2004;66 Suppl 1():S37-43.
2004: Yamada Y; Seino Y
Physiology of GIP--a lesson from GIP receptor knockout mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(11-12):771-4.
2004: Mukai Eri; Kume Noriaki; Hayashida Kazutaka; Minami Manabu; Yamada Yuichiro; Seino Yutaka; Kita Toru
Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized LDL receptor-1 in vascular smooth muscle cells.
Atherosclerosis 2004;176(2):289-96.
2004: Tsukiyama Katsushi; Yamada Yuichiro; Miyawaki Kazumasa; Hamasaki Akihiro; Nagashima Kazuaki; Hosokawa Masaya; Fujimoto Shimpei; Takahashi Akira; Toyoda Kentaro; Toyokuni Shinya; Oiso Yutaka; Seino Yutaka
Gastric inhibitory polypeptide is the major insulinotropic factor in K(ATP) null mice.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(3):407-12.
2004: Fukushima M; Usami M; Ikeda M; Nakai Y; Taniguchi A; Matsuura T; Suzuki H; Kurose T; Yamada Y; Seino Y
Insulin secretion and insulin sensitivity at different stages of glucose tolerance: a cross-sectional study of Japanese type 2 diabetes.
Metabolism: clinical and experimental 2004;53(7):831-5.
2004: Suzuki Haruhiko; Fukushima Mitsuo; Usami Masaru; Ikeda Masaki; Taniguchi Ataru; Nakai Yoshikatsu; Matsuura Toshifumi; Yasuda Koichiro; Hosokawa Masaya; Seino Yutaka; Yamada Yuichiro
IGT with fasting hyperglycemia is more strongly associated with microalbuminuria than IGT without fasting hyperglycemia.
Diabetes research and clinical practice 2004;64(3):213-9.
2004: Inada Akari; Hamamoto Yoshiyuki; Tsuura Yoshiyuki; Miyazaki Jun-ichi; Toyokuni Shinya; Ihara Yu; Nagai Koichiro; Yamada Yuichiro; Bonner-Weir Susan; Seino Yutaka
Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells.
Molecular and cellular biology 2004;24(7):2831-41.
2004: Koshiyama Hiroyuki; Tanaka Kiyoshi; Seino Yutaka
[Obesity and bone metabolism]
Clinical calcium 2004;14(2):248-54.
2004: Kuroe A; Taniguchi A; Sekiguchi A; Ogura M; Murayama Y; Nishimura F; Iwamoto Y; Seino Y; Nagasaka S; Fukushima M; Soga Y; Nakai Y
Prevalence of periodontal bacterial infection in non-obese Japanese type 2 diabetic patients: relationship with C-reactive protein and albuminuria.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(2):116-8.
2003: Oya M; Hosokawa M; Tsukada H; Fukuda K; Nakamura H; Tsukiyama K; Nagashima K; Fujimoto S; Yamada Y; Seino Y
Effects of an aldose reductase inhibitor on gastroenteropathy in streptozotocin-diabetic rats.
Diabetes research and clinical practice 2003;62(2):69-77.
2003: Taniguchi Ataru; Fukushima Mitsuo; Seino Yutaka; Sakai Masahiko; Yoshii Satoru; Nagasaka Shoichiro; Yamauchi Ichizoh; Okumura Takahide; Nin Kazuko; Tokuyama Kunpei; Yamadori Noriko; Ogura Masahito; Kuroe Akira; Nakai Yoshikatsu
Platelet count is independently associated with insulin resistance in non-obese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2003;52(10):1246-9.
2003: Hamamoto Y; Fujimoto S; Inada A; Takehiro M; Nabe K; Shimono D; Kajikawa M; Fujita J; Yamada Y; Seino Y
Beneficial effect of pretreatment of islets with fibronectin on glucose tolerance after islet transplantation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(8):460-5.
2003: Sugawara Fumiaki; Yamada Yuichiro; Watanabe Rie; Ban Nobuhiro; Miyawaki Kazumasa; Kuroe Akira; Hamasaki Akihiro; Ikeda Hiroki; Kurose Takeshi; Usami Masaru; Ikeda Masaki; Seino Yutaka
The role of the TSC-22 (-396) A/G variant in the development of diabetic nephropathy.
Diabetes research and clinical practice 2003;60(3):191-7.
2003: Suzuki Haruhiko; Fukushima Mitsuo; Usami Masaru; Ikeda Masaki; Taniguchi Ataru; Nakai Yosikatsu; Matsuura Toshifumi; Kuroe Akira; Yasuda Koichiro; Kurose Takeshi; Seino Yutaka; Yamada Yuichiro
Factors responsible for development from normal glucose tolerance to isolated postchallenge hyperglycemia.
Diabetes care 2003;26(4):1211-5.
2003: Fujimoto Shimpei; Matsushima Aki; Yoshitani Kazuyasu; Oya Michihiro; Shimono Dai; Takeda Tomomi; Kurose Takeshi; Yamada Yuichiro; Seino Yutaka
Type-1 diabetes mellitus with insufficient serum immunoreactive insulin elevation after subcutaneous NPH-insulin injection.
Diabetes research and clinical practice 2003;60(1):69-73.
2003: Suzuki Naoko; Matsunaga Tetsuro; Nagasumi Kae; Yamamura Tsubasa; Shihara Nobuyuki; Moritani Toshio; Ue Hidetoshi; Fukushima Mitsuo; Tamon Akiko; Seino Yutaka; Tsuda Kinsuke; Yasuda Koichiro
Alpha(2B)-adrenergic receptor deletion polymorphism associates with autonomic nervous system activity in young healthy Japanese.
The Journal of clinical endocrinology and metabolism 2003;88(3):1184-7.
2003: Taniguchi Ataru; Nishimura Fusanori; Murayama Yoji; Nagasaka Shoichiro; Fukushima Mitsuo; Sakai Masahiko; Yoshii Satoru; Kuroe Akira; Suzuki Haruhiko; Iwamoto Yoshihiro; Soga Yoshihiko; Okumura Takahide; Ogura Masahito; Yamada Yuichiro; Seino Yutaka; Nakai Yoshikatsu
Porphyromonas gingivalis infection is associated with carotid atherosclerosis in non-obese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2003;52(2):142-5.
2003: Yasuda K; Shimowada K; Uno M; Odaka H; Adachi T; Shihara N; Suzuki N; Tamon A; Nagashima K; Hosokawa M; Tsuda K; Seino Y
Long-term therapeutic effects of voglibose, a potent intestinal alpha-glucosidase inhibitor, in spontaneous diabetic GK rats.
Diabetes research and clinical practice 2003;59(2):113-22.
2003: Kuroe Akira; Fukushima Mitsuo; Usami Masaru; Ikeda Masaki; Nakai Yoshikatsu; Taniguchi Ataru; Matsuura Toshifumi; Suzuki Haruhiko; Kurose Takeshi; Yasuda Koichiro; Yamada Yuichiro; Seino Yutaka
Impaired beta-cell function and insulin sensitivity in Japanese subjects with normal glucose tolerance.
Diabetes research and clinical practice 2003;59(1):71-7.
2002: Taniguchi Ataru; Nagasaka Shoichiro; Fukushima Mitsuo; Sakai Masahiko; Okumura Takahide; Yoshii Satoru; Watanabe Toshiki; Ogura Masahito; Yamadori Noriko; Nin Kazuko; Kuroe Akira; Yamada Yuichiro; Seino Yutaka; Nakai Yoshikatsu
C-reactive protein and insulin resistance in non-obese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2002;51(12):1578-81.
2002: Yasuda Koichiro; Nishikawa Waka; Iwanaka Nobumasa; Nakamura Eitaro; Seino Yutaka; Tsuda Kinsuke; Ishihara Akihiko
Abnormality in fibre type distribution of soleus and plantaris muscles in non-obese diabetic Goto-Kakizaki rats.
Clinical and experimental pharmacology & physiology 2002;29(11):1001-8.
2002: Kajikawa Mariko; Fujimoto Shimpei; Tsuura Yoshiyuki; Mukai Eri; Takeda Tomomi; Hamamoto Yoshiyuki; Takehiro Mihoko; Fujita Jun; Yamada Yuichiro; Seino Yutaka
Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets.
Diabetes 2002;51(8):2522-9.
2002: Nabe Koichiro; Seino Yutaka
[Hexokinase]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():542-7.
2002: Naitoh Rei; Seino Yutaka
[Oxidative stress and development of type 1 diabetes]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():395-8.
2002: Fukuda Kazuhito; Seino Yutaka
[The other gastrointestinal hormones in diabetes mellitus]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():291-7.
2002: Ueno Hiroyuki; Kurose Takeshi; Seino Yutaka
[History and perspective of classification for diabetes mellitus]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():28-35.
2002: Fukuda Kazuhito; Seino Yutaka
[Gastrointestinal hormones in diabetes mellitus]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():259-64.
2002: Inada Akari; Seino Yutaka
[The regulation of insulin gene transcription by transcription factors]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():159-64.
2002: Yamada Yuichiro; Seino Yutaka
[Review: regulation of glucose metabolism]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():153-8.
2002: Miyawaki Kazumasa; Yamada Yuichiro; Ban Nobuhiro; Ihara Yu; Tsukiyama Katsushi; Zhou Heying; Fujimoto Shimpei; Oku Akira; Tsuda Kinsuke; Toyokuni Shinya; Hiai Hiroshi; Mizunoya Wataru; Fushiki Tohru; Holst Jens Juul; Makino Mitsuhiro; Tashita Akira; Kobara Yukari; Tsubamoto Yoshiharu; Jinnouchi Takayoshi; Jomori Takahito; Seino Yutaka
Inhibition of gastric inhibitory polypeptide signaling prevents obesity.
Nature medicine 2002;8(7):738-42.
2002: Ban Nobuhiro; Yamada Yuichiro; Someya Yoshimichi; Miyawaki Kazumasa; Ihara Yu; Hosokawa Masaya; Toyokuni Shinya; Tsuda Kinsuke; Seino Yutaka
Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter.
Diabetes 2002;51(5):1409-18.
2002: Yasuda K; Okamoto Y; Nunoi K; Adachi T; Shihara N; Tamon A; Suzuki N; Mukai E; Fujimoto S; Oku A; Tsuda K; Seino Y
Normalization of cytoplasmic calcium response in pancreatic beta-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(4):217-21.
2002: Fujimoto Shimpei; Mukai Eri; Hamamoto Yoshiyuki; Takeda Tomomi; Takehiro Mihoko; Yamada Yuichiro; Seino Yutaka
Prior exposure to high glucose augments depolarization-induced insulin release by mitigating the decline of ATP level in rat islets.
Endocrinology 2002;143(1):213-21.
2001: Sugawara F; Yamada Y; Kuroe A; Someya Y; Kubota A; Ihara Y; Takahashi K; Seino Y
Human TSC-22 gene: no association with type 2 diabetes.
Internal medicine (Tokyo, Japan) 2001;40(10):993-7.
2001: Hamamoto Y; Tsuura Y; Fujimoto S; Nagata M; Takeda T; Mukai E; Fujita J; Yamada Y; Seino Y
Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation.
Biochemical and biophysical research communications 2001;287(1):104-9.
2001: Fukushima M; Taniguchi A; Nakai Y; Sakai M; Doi K; Nin K; Oguma T; Nagasaka S; Tokuyama K; Seino Y
Remnant-like particle cholesterol and insulin resistance in nonobese nonhypertensive Japanese glucose-tolerant relatives of type 2 diabetic patients.
Diabetes care 2001;24(9):1691-4.
2001: Shen Z P; Nishimura M; Tsuura Y; Fujimoto S; Mukai E; Yamada Y; Seino Y
Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets.
Diabetes research and clinical practice 2001;53(1):9-16.
2001: Shihara N; Yasuda K; Moritani T; Ue H; Uno M; Adachi T; Nunoi K; Seino Y; Yamada Y; Tsuda K
Synergistic effect of polymorphisms of uncoupling protein 1 and beta3-adrenergic receptor genes on autonomic nervous system activity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(6):761-6.
2001: Takeda T; Tsuura Y; Fujita J; Fujimoto S; Mukai E; Kajikawa M; Hamamoto Y; Kume M; Yamamoto Y; Yamaoka Y; Yamada Y; Seino Y
Heat shock restores insulin secretion after injury by nitric oxide by maintaining glucokinase activity in rat islets.
Biochemical and biophysical research communications 2001;284(1):20-5.
2001: Yamada Y; Kuroe A; Li Q; Someya Y; Kubota A; Ihara Y; Tsuura Y; Seino Y
Genomic variation in pancreatic ion channel genes in Japanese type 2 diabetic patients.
Diabetes/metabolism research and reviews 2001;17(3):213-6.
2001: Horie M; Mizuno N; Tsuji K; Haruna T; Ninomiya T; Ishida H; Seino Y; Sasayama S
Disopyramide and its metabolite enhance insulin release from clonal pancreatic beta-cells by blocking K(ATP) channels.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(1):31-9.
2001: Shiraishi A; Yamada Y; Tsuura Y; Fijimoto S; Tsukiyama K; Mukai E; Toyoda Y; Miwa I; Seino Y
A novel glucokinase regulator in pancreatic beta cells: precursor of propionyl-CoA carboxylase beta subunit interacts with glucokinase and augments its activity.
The Journal of biological chemistry 2001;276(4):2325-8.
2000: Fujimoto S; Tsuura Y; Ishida H; Tsuji K; Mukai E; Kajikawa M; Hamamoto Y; Takeda T; Yamada Y; Seino Y
Augmentation of basal insulin release from rat islets by preexposure to a high concentration of glucose.
American journal of physiology. Endocrinology and metabolism 2000;279(4):E927-40.
2000: Onomura M; Tsukada H; Fukuda K; Kodama M; Nakamura H; Hosokawa M; Ohya M; Seino Y
Effect of argatroban on trinitrobenzene sulfonic acid-induced colitis.
Journal of gastroenterology and hepatology 2000;15(8):931-8.
2000: Adachi T; Yasuda K; Okamoto Y; Shihara N; Oku A; Ueta K; Kitamura K; Saito A; Iwakura I; Yamada Y; Yano H; Seino Y; Tsuda K
T-1095, a renal Na+-glucose transporter inhibitor, improves hyperglycemia in streptozotocin-induced diabetic rats.
Metabolism: clinical and experimental 2000;49(8):990-5.
2000: Ban N; Yamada Y; Someya Y; Ihara Y; Adachi T; Kubota A; Watanabe R; Kuroe A; Inada A; Miyawaki K; Sunaga Y; Shen Z P; Iwakura T; Tsukiyama K; Toyokuni S; Tsuda K; Seino Y
Activating transcription factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression.
Diabetes 2000;49(7):1142-8.
2000: Ajiro K; Sawamura M; Ikeda K; Nara Y; Nishimura M; Ishida H; Seino Y; Yamori Y
Beneficial effects of fish oil on glucose metabolism in spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 2000;27(5-6):412-5.
2000: Hosokawa M; Tsukada H; Fukuda F; Oya M; Onomura M; Nakamura H; Kodama M; Fujita J; Seino Y
Therapeutic effect of basic fibroblast growth factor on experimental pancreatitis in rat.
Pancreas 2000;20(4):373-7.
2000: Ihara Y; Yamada Y; Toyokuni S; Miyawaki K; Ban N; Adachi T; Kuroe A; Iwakura T; Kubota A; Hiai H; Seino Y
Antioxidant alpha-tocopherol ameliorates glycemic control of GK rats, a model of type 2 diabetes.
FEBS letters 2000;473(1):24-6.
2000: Iwakura T; Fujimoto S; Kagimoto S; Inada A; Kubota A; Someya Y; Ihara Y; Yamada Y; Seino Y
Sustained enhancement of Ca(2+) influx by glibenclamide induces apoptosis in RINm5F cells.
Biochemical and biophysical research communications 2000;271(2):422-8.
2000: Kodama M; Tsukada H; Ooya M; Onomura M; Saito T; Fukuda K; Nakamura H; Taniguchi T; Tominaga M; Hosokawa M; Fujita J; Seino Y
Gastric mucosal damage caused by monochloramine in the rat and protective effect of taurine: endoscopic observation through gastric fistula.
Endoscopy 2000;32(4):294-9.
2000: Nunoi K; Yasuda K; Tanaka H; Kubota A; Okamoto Y; Adachi T; Shihara N; Uno M; Xu L M; Kagimoto S; Seino Y; Yamada Y; Tsuda K
Wortmannin, a PI3-kinase inhibitor: promoting effect on insulin secretion from pancreatic beta cells through a cAMP-dependent pathway.
Biochemical and biophysical research communications 2000;270(3):798-805.
2000: Horie M; Watanuki M; Tsuji K; Ishida H; Ishida-Takahashi A; Yuzuki Y; Seino Y; Sasayama S
Blockade of cardiac ATP-sensitive K+ channel by cibenzoline targets its pore-forming subunit.
Journal of cardiovascular pharmacology 2000;35(3):434-42.
2000: Mukai E; Ishida H; Fujimoto S; Kajikawa M; Okamoto Y; Fujita J; Hamamoto Y; Tsuura Y; Yamada Y; Furukawa N; Ohta T; Seino Y
The insulinotropic mechanism of the novel hypoglycaemic agent JTT-608: direct enhancement of Ca(2+) efficacy and increase of Ca(2+) influx by phosphodiesterase inhibition.
British journal of pharmacology 2000;129(5):901-8.
2000: Yamada Y; Seino Y
[Genetic factors and insulin resistance]
Nippon rinsho. Japanese journal of clinical medicine 2000;58(2):315-9.
1999: Fukuda K; Oya M; Seino Y
[Pancreatic polypeptide (PP)]
Nippon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():353-6.
1999: Naruse M M; Ohara I; Kobayashi T; Itokawa Y; Seino Y
Effects of taste stimulation on the behavior of serum amino acid concentrations and amylase and trypsin activities in fasting rats.
Journal of nutritional science and vitaminology 1999;45(6):733-46.
1999: Ihara Y; Yamada Y; Seino Y
[Multiple risk factor syndrome]
Nippon rinsho. Japanese journal of clinical medicine 1999;57(12):2801-5.
1999: Miyawaki K; Yamada Y; Yano H; Niwa H; Ban N; Ihara Y; Kubota A; Fujimoto S; Kajikawa M; Kuroe A; Tsuda K; Hashimoto H; Yamashita T; Jomori T; Tashiro F; Miyazaki J; Seino Y
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14843-7.
1999: Nakamura H; Tsukada H; Oya M; Onomura M; Saito T; Fukuda K; Kodama M; Taniguchi T; Tominaga M; Hosokawa M; Seino Y
Aminoguanidine has both an anti-inflammatory effect on experimental colitis and a proliferative effect on colonic mucosal cells.
Scandinavian journal of gastroenterology 1999;34(11):1117-22.
1999: Kajikawa M; Ishida H; Fujimoto S; Mukai E; Nishimura M; Fujita J; Tsuura Y; Okamoto Y; Norman A W; Seino Y
An insulinotropic effect of vitamin D analog with increasing intracellular Ca2+ concentration in pancreatic beta-cells through nongenomic signal transduction.
Endocrinology 1999;140(10):4706-12.
1999: Sunaga Y; Inagaki N; Gonoi T; Yamada Y; Ishida H; Seino Y; Seino S
Troglitazone but not pioglitazone affects ATP-sensitive K(+) channel activity.
European journal of pharmacology 1999;381(1):71-6.
1999: Hosokawa M; Tsukada H; Fukuda K; Oya M; Onomura M; Nakamura H; Kodama M; Yamada Y; Seino Y
Troglitazone inhibits bicarbonate secretion in rat and human duodenum.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1080-4.
1999: Tsuura Y; Fujimoto S; Kajikawa M; Ishida H; Seino Y
Regulation of intracellular ATP concentration under conditions of reduced ATP consumption in pancreatic islets.
Biochemical and biophysical research communications 1999;261(2):439-44.
1999: Inada A; Someya Y; Yamada Y; Ihara Y; Kubota A; Ban N; Watanabe R; Tsuda K; Seino Y
The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID.
The Journal of biological chemistry 1999;274(30):21095-103.
1999: Nakai Y; Hamagaki S; Kato S; Seino Y; Takagi R; Kurimoto F
Role of leptin in women with eating disorders.
The International journal of eating disorders 1999;26(1):29-35.
1999: Fujita J; Tsuda K; Takeda T; Yu L; Fujimoto S; Kajikawa M; Nishimura M; Mizuno N; Hamamoto Y; Mukai E; Adachi T; Seino Y
Nisoldipine improves the impaired erythrocyte deformability correlating with elevated intracellular free calcium-ion concentration and poor glycaemic control in NIDDM.
British journal of clinical pharmacology 1999;47(5):499-506.
1999: Shihara N; Yasuda K; Moritani T; Ue H; Adachi T; Tanaka H; Tsuda K; Seino Y
The association between Trp64Arg polymorphism of the beta3-adrenergic receptor and autonomic nervous system activity.
The Journal of clinical endocrinology and metabolism 1999;84(5):1623-7.
1999: Ihara Y; Toyokuni S; Uchida K; Odaka H; Tanaka T; Ikeda H; Hiai H; Seino Y; Yamada Y
Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.
Diabetes 1999;48(4):927-32.
1999: Yamada Y; Seino Y
[Pathogenesis of impaired insulin secretion in NIDDM]
Nippon rinsho. Japanese journal of clinical medicine 1999;57(3):534-8.
1999: Nakai Y; Hamagaki S; Kato S; Seino Y; Takagi R; Kurimoto F
Leptin in women with eating disorders.
Metabolism: clinical and experimental 1999;48(2):217-20.
1999: Watanabe R; Yamada Y; Ihara Y; Someya Y; Kubota A; Kagimoto S; Kuroe A; Iwakura T; Shen Z P; Inada A; Adachi T; Ban N; Miyawaki K; Sunaga Y; Tsuda K; Seino Y
The MH1 domains of smad2 and smad3 are involved in the regulation of the ALK7 signals.
Biochemical and biophysical research communications 1999;254(3):707-12.
1999: Onomura M; Tsukada H; Fukuda K; Hosokawa M; Nakamura H; Kodama M; Ohya M; Seino Y
Effects of ginseng radix on sugar absorption in the small intestine.
The American journal of Chinese medicine 1999;27(3-4):347-54.
1999: Fukuda K; Tsukada H; Oya M; Onomura M; Kodama M; Nakamura H; Hosokawa M; Seino Y
Adrenomedullin promotes epithelial restitution of rat and human gastric mucosa in vitro.
Peptides 1999;20(1):127-32.
1998: Inada A; Yamada Y; Someya Y; Kubota A; Yasuda K; Ihara Y; Kagimoto S; Kuroe A; Tsuda K; Seino Y
Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats.
Biochemical and biophysical research communications 1998;253(3):712-8.
1998: Ishida H; Kato S; Nishimura M; Mizuno N; Fujimoto S; Mukai E; Kajikawa M; Yamada Y; Odaka H; Ikeda H; Seino Y
Beneficial effect of long-term combined treatment with voglibose and pioglitazone on pancreatic islet function of genetically diabetic GK rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1998;30(11):673-8.
1998: Hosokawa M; Tsukada H; Saitou T; Kodama M; Onomura M; Nakamura H; Fukuda K; Seino Y
Effects of okadaic acid on rat colon.
Digestive diseases and sciences 1998;43(11):2526-35.
1998: Tsuura Y; Ishida H; Shinomura T; Nishimura M; Seino Y
Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets.
Biochemical and biophysical research communications 1998;252(1):34-8.
1998: Mukai E; Ishida H; Horie M; Noma A; Seino Y; Takano M
The antiarrhythmic agent cibenzoline inhibits KATP channels by binding to Kir6.2.
Biochemical and biophysical research communications 1998;251(2):477-81.
1998: Taniguchi T; Tsukada H; Nakamura H; Kodama M; Fukuda K; Saito T; Miyasaka M; Seino Y
Effects of the anti-ICAM-1 monoclonal antibody on dextran sodium sulphate-induced colitis in rats.
Journal of gastroenterology and hepatology 1998;13(9):945-9.
1998: Tsuura Y; Ishida H; Nishimura M; Fujimoto S; Kajikawa M; Seino Y
Ouabain suppresses ATP elevation in response to fuel secretagogues in pancreatic islets.
Biochemical and biophysical research communications 1998;249(3):853-7.
1998: Suzuki K; Ishida H; Takeshita N; Taguchi Y; Sugimoto C; Nosaka K; Seino Y
Circulating levels of tartrate-resistant acid phosphatase in rat models of non-insulin-dependent diabetes mellitus.
Journal of diabetes and its complications 1998;12(3):176-80.
1998: Mizuno N; Yoshitomi H; Ishida H; Kuromi H; Kawaki J; Seino Y; Seino S
Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion.
Endocrinology 1998;139(3):1429-39.
1998: Fujimoto S; Ishida H; Kato S; Okamoto Y; Tsuji K; Mizuno N; Ueda S; Mukai E; Seino Y
The novel insulinotropic mechanism of pimobendan: direct enhancement of the exocytotic process of insulin secretory granules by increased Ca2+ sensitivity in beta-cells.
Endocrinology 1998;139(3):1133-40.
1998: Nishimura M; Ishida H; Tsuura Y; Kato S; Mizuno N; Fujimoto S; Mukai E; Kajikawa M; Usami M; Seino Y
Necessity of endogenous GTP derived from glucose-6-phosphate for insulin secretion augmented by glucose under protein kinase A activation.
Biochemical and biophysical research communications 1998;243(1):253-7.
1998: Fujita J; Seino Y; Tsuda K
[Erythrocyte Na+/Li+ countertransport activity]
Nippon rinsho. Japanese journal of clinical medicine 1998;56 Suppl 3():251-7.
1998: Mukai E; Ishida H; Kato S; Tsuura Y; Fujimoto S; Ishida-Takahashi A; Horie M; Tsuda K; Seino Y
Metabolic inhibition impairs ATP-sensitive K+ channel block by sulfonylurea in pancreatic beta-cells.
The American journal of physiology 1998;274(1 Pt 1):E38-44.
1998: Fukuda K; Tsukada H; Onomura M; Saito T; Kodama M; Nakamura H; Taniguchi T; Tominaga M; Hosokawa M; Seino Y
Effect of adrenomedullin on ion transport and muscle contraction in rat distal colon.
Peptides 1998;19(6):1043-7.
1997: Nishimura M; Seino Y
[Secondary forms of diabetes]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():519-27.
1997: Kubota A; Seino Y
[Hexokinase gene]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():478-81.
1997: Fukuda K; Tsukada H; Seino Y
[Gastrointestinal hormones in diabetes mellitus]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():149-54.
1997: Someya Y; Ishida H; Seino Y
[Insulin gene: gene organization and its regulatory mechanism of transcription]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():73-8.
1997: Seino Y; Someya Y
[Review: regulatory factors of glucose metabolism]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():67-72.
1997: Fujita J; Tsuda K; Obayashi H; Fukui I; Ishida H; Seino Y
Nisoldipine blocks the increase of intracellular free calcium-ion concentration associated with elevated sodium-lithium countertransport activity in erythrocytes in patients with NIDDM.
Diabetic medicine : a journal of the British Diabetic Association 1997;14(6):499-502.
1997: Kubota A; Yamada Y; Yasuda K; Someya Y; Ihara Y; Kagimoto S; Watanabe R; Kuroe A; Ishida H; Seino Y
Gastric inhibitory polypeptide activates MAP kinase through the wortmannin-sensitive and -insensitive pathways.
Biochemical and biophysical research communications 1997;235(1):171-5.
1997: Horie M; Ishida-Takahashi A; Ai T; Nishimoto T; Tsuura Y; Ishida H; Seino Y; Sasayama S
Insulin secretion and its modulation by antiarrhythmic and sulfonylurea drugs.
Cardiovascular research 1997;34(1):69-72.
1997: Yamada Y; Seino Y
[Sulfonylurea receptor]
Nippon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 2():590-3.
1997: Taniguchi T; Tsukada H; Nakamura H; Kodama M; Fukuda K; Tominaga M; Seino Y
Effects of a thromboxane A2 receptor antagonist in an animal model of inflammatory bowel disease.
Digestion 1997;58(5):476-8.
1996: Kubota A; Yamada Y; Hayami T; Yasuda K; Someya Y; Ihara Y; Kagimoto S; Watanabe R; Taminato T; Tsuda K; Seino Y
Identification of two missense mutations in the GIP receptor gene: a functional study and association analysis with NIDDM: no evidence of association with Japanese NIDDM subjects.
Diabetes 1996;45(12):1701-5.
1996: Okada N; Kubota A; Imamura T; Suwa H; Kawaguchi Y; Ohshio G; Seino Y; Imamura M
Evaluation of cholecystokinin, gastrin, CCK-A receptor, and CCK-B/gastrin receptor gene expressions in gastric cancer.
Cancer letters 1996;106(2):257-62.
1996: Kubota A; Yamada Y; Kagimoto S; Seino S; Seino Y
Effector coupling of somatostatin receptor subtypes on human endocrine tumors.
Metabolism: clinical and experimental 1996;45(8 Suppl 1):42-5.
1996: Kato S; Ishida H; Tsuura Y; Tsuji K; Nishimura M; Horie M; Taminato T; Ikehara S; Odaka H; Ikeda I; Okada Y; Seino Y
Alterations in basal and glucose-stimulated voltage-dependent Ca2+ channel activities in pancreatic beta cells of non-insulin-dependent diabetes mellitus GK rats.
The Journal of clinical investigation 1996;97(11):2417-25.
1996: Yamada Y; Seino Y
[Somatostatin and its receptors]
Nippon rinsho. Japanese journal of clinical medicine 1996;54(4):1109-14.
1996: Yasuda K; Seino Y
[Gastric inhibitory polypeptide (GIP) and GIP receptor (GIPR)]
Nippon rinsho. Japanese journal of clinical medicine 1996;54(4):1078-82.
1996: Miyamoto K; Ogura Y; Nishiwaki H; Matsuda N; Honda Y; Kato S; Ishida H; Seino Y
Evaluation of retinal microcirculatory alterations in the Goto-Kakizaki rat. A spontaneous model of non-insulin-dependent diabetes.
Investigative ophthalmology & visual science 1996;37(5):898-905.
1996: Inomoto T; Tanaka A; Awane M; Kanai M; Shinohara H; Hatano S; Sato S; Gomi T; Masuda K; Someya Y; Honda K; Seino Y; Yamaoka Y
Changes in glucose transporter 2 and carbohydrate-metabolizing enzymes in the liver during cold preservation and warm ischemia.
Transplantation 1996;61(6):869-74.
1996: Fujita J; Tsuda K; Seno M; Obayashi H; Fukui I; Seino Y
Elevated erythrocyte sodium-lithium countertransport activity correlates with increased intracellular sodium and free calcium-ion concentration in type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(1):53-8.
1995: Suzuki K; Ishida H; Sugimoto C; Taguchi Y; Matsuda H; Nosaka K; Someya Y; Kadowaki S; Seino Y
The urinary concentration of sialic acid is increased in non-insulin-dependent diabetic patients with microangiopathy: a possible useful marker for diabetic microangiopathy.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(12):1092-6.
1995: Kato S; Ishida H; Tsuura Y; Seino Y
Altered functions of ion channels in diabetic beta cells.
Obesity research 1995;3 Suppl 5():637S-638S.
1995: Yamada Y; Hayami T; Nakamura K; Kaisaki P J; Someya Y; Wang C Z; Seino S; Seino Y
Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA.
Genomics 1995;29(3):773-6.
1995: Okamoto Y; Ishida H; Tsuura Y; Yasuda K; Kato S; Matsubara H; Nishimura M; Mizuno N; Ikeda H; Seino Y
Hyperresponse in calcium-induced insulin release from electrically permeabilized pancreatic islets of diabetics GK rats and its defective augmentation by glucose.
Diabetologia 1995;38(7):772-8.
1995: Tsuda K; Seino Y
[Genetic syndrome with obesity]
Nippon rinsho. Japanese journal of clinical medicine 1995;53 Suppl():436-40.
1995: Yamada Y; Masuda K; Li Q; Ihara Y; Kubota A; Miura T; Nakamura K; Fujii Y; Seino S; Seino Y
The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.
Genomics 1995;27(2):312-9.
1995: Seino Y; Ishida H
Diabetic osteopenia: pathophysiology and clinical aspects.
Diabetes/metabolism reviews 1995;11(1):21-35.
1995: Seino Y
[Pancreatic polypeptide (PP)]
Nippon rinsho. Japanese journal of clinical medicine 1995;53 Su Pt 2():648-50.
1995: Ihara Y; Yamada Y; Fujii Y; Gonoi T; Yano H; Yasuda K; Inagaki N; Seino Y; Seino S
Molecular diversity and functional characterization of voltage-dependent calcium channels (CACN4) expressed in pancreatic beta-cells.
Molecular endocrinology (Baltimore, Md.) 1995;9(1):121-30.
1995: Masuda K; Okamoto Y; Tsuura Y; Kato S; Miura T; Tsuda K; Horikoshi H; Ishida H; Seino Y
Effects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide.
Diabetologia 1995;38(1):24-30.
1994: Yasuda K; Inagaki N; Yamada Y; Kubota A; Seino S; Seino Y
Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells: its structure and functional properties.
Biochemical and biophysical research communications 1994;205(3):1556-62.
1994: Tsuura Y; Ishida H; Hayashi S; Sakamoto K; Horie M; Seino Y
Nitric oxide opens ATP-sensitive K+ channels through suppression of phosphofructokinase activity and inhibits glucose-induced insulin release in pancreatic beta cells.
The Journal of general physiology 1994;104(6):1079-98.
1994: Tsuura Y; Ishida H; Okamoto Y; Kato S; Horie M; Ikeda H; Seino Y
Reduced sensitivity of dihydroxyacetone on ATP-sensitive K+ channels of pancreatic beta cells in GK rats.
Diabetologia 1994;37(11):1082-7.
1994: Kato S; Ishida H; Tsuura Y; Okamoto Y; Tsuji K; Horie M; Okada Y; Seino Y
Increased calcium-channel currents of pancreatic beta cells in neonatally streptozocin-induced diabetic rats.
Metabolism: clinical and experimental 1994;43(11):1395-400.
1994: Yasuda K; Seino Y
[Candidate gene approach in Japanese NIDDM: liver/pancreatic beta cell type glucose transporter (GLUT2)]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2693-6.
1994: Seino Y; Yamada Y
[Heterogeneity in pathogenesis of NIDDM and recent advances in research of diabetogenic genes]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2686-92.
1994: Masuda K; Li Q; Yamada Y; Seino Y
[The alpha 1 subunit of voltage-dependent calcium channel expressed in pancreatic beta cells]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2593-8.
1994: Miura T; Yamada Y; Someya Y; Kubota A; Seino Y
[The detection of GLUT2 gene mutation by polymerase-chain reaction single stranded conformation polymorphism (PCR-SSCP) method]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2568-71.
1994: Someya Y; Fukumoto H; Seino Y
[Organization of the human GLUT2 gene and regulation of the GLUT2 gene expression]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(10):2562-7.
1994: Seino Y; Imura H
Endocrine disorders and diabetes in Japan.
Diabetes research and clinical practice 1994;24 Suppl():S129-33.
1994: Kubota A; Yamada Y; Kagimoto S; Yasuda K; Someya Y; Ihara Y; Okamoto Y; Kozasa T; Seino S; Seino Y
Multiple effector coupling of somatostatin receptor subtype SSTR1.
Biochemical and biophysical research communications 1994;204(1):176-86.
1994: Fujita J; Tsuda K; Seno M; Obayashi H; Fukui I; Seino Y
Erythrocyte sodium-lithium countertransport activity as a marker of predisposition to hypertension and diabetic nephropathy in NIDDM.
Diabetes care 1994;17(9):977-82.
1994: Li Q; Yamada Y; Yasuda K; Ihara Y; Okamoto Y; Kaisaki P J; Watanabe R; Ikeda H; Tsuda K; Seino Y
A cloned rat CD38-homologous protein and its expression in pancreatic islets.
Biochemical and biophysical research communications 1994;202(1):629-36.
1994: Kagimoto S; Yamada Y; Kubota A; Someya Y; Ihara Y; Yasuda K; Kozasa T; Imura H; Seino S; Seino Y
Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein.
Biochemical and biophysical research communications 1994;202(2):1188-95.
1994: Kubota A; Yamada Y; Kagimoto S; Shimatsu A; Imamura M; Tsuda K; Imura H; Seino S; Seino Y
Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors.
The Journal of clinical investigation 1994;93(3):1321-5.
1994: Masuda K; Yano H; Miura T; Morimoto M; Kitano N; Seino Y
Hind III site causing Proinsulin Kyoto and Pst I site polymorphism of the insulin gene in Japanese: its lack of association with either IDDM or NIDDM.
Endocrine journal 1994;41(1):71-4.
1994: Takagi H; Tanihara H; Seino Y; Yoshimura N
Characterization of glucose transporter in cultured human retinal pigment epithelial cells: gene expression and effect of growth factors.
Investigative ophthalmology & visual science 1994;35(1):170-7.
1993: Tsuji K; Taminato T; Ishida H; Okamoto Y; Tsuura Y; Kato S; Kurose T; Okada Y; Imura H; Seino Y
Selective impairment of the cytoplasmic Ca2+ response to glucose in pancreatic beta cells of streptozocin-induced non-insulin-dependent diabetic rats.
Metabolism: clinical and experimental 1993;42(11):1424-8.
1993: Tsuura Y; Ishida H; Okamoto Y; Kato S; Sakamoto K; Horie M; Ikeda H; Okada Y; Seino Y
Glucose sensitivity of ATP-sensitive K+ channels is impaired in beta-cells of the GK rat. A new genetic model of NIDDM.
Diabetes 1993;42(10):1446-53.
1993: Hayashi S; Horie M; Tsuura Y; Ishida H; Okada Y; Seino Y; Sasayama S
Disopyramide blocks pancreatic ATP-sensitive K+ channels and enhances insulin release.
The American journal of physiology 1993;265(2 Pt 1):C337-42.
1993: Someya Y; Inagaki N; Maekawa T; Seino Y; Ishii S
Two 3',5'-cyclic-adenosine monophosphate response elements in the promoter region of the human gastric inhibitory polypeptide gene.
FEBS letters 1993;317(1-2):67-73.
1993: Takeshita N; Ishida H; Yamamoto T; Koh G; Kurose T; Tsuji K; Okamoto Y; Ikeda H; Seino Y
Circulating levels and bone contents of bone gamma-carboxyglutamic acid-containing protein in rat models of non-insulin-dependent diabetes mellitus.
Acta endocrinologica 1993;128(1):69-73.
1993: Seino Y; Yamamoto T; Inoue K; Imamura M; Kadowaki S; Kojima H; Fujikawa J; Imura H
Abnormal facilitative glucose transporter gene expression in human islet cell tumors.
The Journal of clinical endocrinology and metabolism 1993;76(1):75-8.
1993: Gu X H; Kurose T; Kato S; Masuda K; Tsuda K; Ishida H; Seino Y
Suppressive effect of GABA on insulin secretion from the pancreatic beta-cells in the rat.
Life sciences 1993;52(8):687-94.
1992: Okamoto Y; Ishida H; Taminato T; Tsuji K; Kurose T; Tsuura Y; Kato S; Imura H; Seino Y
Role of cytosolic Ca2+ in impaired sensitivity to glucose of rat pancreatic islets exposed to high glucose in vitro.
Diabetes 1992;41(12):1555-61.
1992: Yamada Y; Reisine T; Law S F; Ihara Y; Kubota A; Kagimoto S; Seino M; Seino Y; Bell G I; Seino S
Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2136-42.
1992: Kurose T; Tsuda K; Ishida H; Tsuji K; Okamoto Y; Tsuura Y; Kato S; Usami M; Imura H; Seino Y
Glucagon, insulin and somatostatin secretion in response to sympathetic neural activation in streptozotocin-induced diabetic rats. A study with the isolated perfused rat pancreas in vitro.
Diabetologia 1992;35(11):1035-41.
1992: Tsuura Y; Ishida H; Okamoto Y; Tsuji K; Kurose T; Horie M; Imura H; Okada Y; Seino Y
Impaired glucose sensitivity of ATP-sensitive K+ channels in pancreatic beta-cells in streptozotocin-induced NIDDM rats.
Diabetes 1992;41(7):861-5.
1992: Ishida H; Seino Y; Takeshita N; Kurose T; Tsuji K; Okamoto Y; Someya Y; Hara K; Akiyama Y; Imura H
Effect of pancreas transplantation on decreased levels of circulating bone gamma-carboxyglutamic acid-containing protein and osteopenia in rats with streptozotocin-induced diabetes.
Acta endocrinologica 1992;127(1):81-5.
1992: Yano H; Kitano N; Morimoto M; Polonsky K S; Imura H; Seino Y
A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto).
The Journal of clinical investigation 1992;89(6):1902-7.
1992: Seino Y; Yamamoto T; Koh G
Insulin and glucose transporter gene expression in obesity and diabetes.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;200(2):210-3.
1992: Inagaki N; Maekawa T; Sudo T; Ishii S; Seino Y; Imura H
c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(3):1045-9.
1992: Yasuda K; Yamada Y; Inagaki N; Yano H; Okamoto Y; Tsuji K; Fukumoto H; Imura H; Seino S; Seino Y
Expression of GLUT1 and GLUT2 glucose transporter isoforms in rat islets of Langerhans and their regulation by glucose.
Diabetes 1992;41(1):76-81.
1991: Seino Y; Ishida H
The pathophysiology and etiology of diabetic osteopenia.
Japanese journal of medicine 1991;30(6):624-6.
1991: Seino Y; Ishida H
[Diabetes mellitus and its complications in Japan. The pathophysiology and etiology of diabetic osteopenia]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1991;80(9):1446-50.
1991: Yamamoto T; Fukumoto H; Koh G; Yano H; Yasuda K; Masuda K; Ikeda H; Imura H; Seino Y
Liver and muscle-fat type glucose transporter gene expression in obese and diabetic rats.
Biochemical and biophysical research communications 1991;175(3):995-1002.
1991: Imura H; Kuzuya H; Seino Y
[MHC class II antigen and other genes in NIDDM]
Nippon rinsho. Japanese journal of clinical medicine 1991;49 Suppl():531-6.
1991: Yano H; Seino Y; Inagaki N; Hinokio Y; Yamamoto T; Yasuda K; Masuda K; Someya Y; Imura H
Tissue distribution and species difference of the brain type glucose transporter (GLUT3).
Biochemical and biophysical research communications 1991;174(2):470-7.
1990: Imura H; Seino Y; Fukumoto H
[Glucose transporters]
Nippon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():39-47.
1990: Tsuda K; Seino Y
[Secondary diabetes]
Nippon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():203-8.
1990: Seino Y; Yano H; Inagaki N
[Gastrointestinal hormones in diabetes mellitus]
Nippon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():113-9.
1990: Koh G; Seino Y; Usami M; Matsuo T; Ikeda H; Yamamoto T; Tsuda K; Taminato T; Imura H
Importance of imparied insulin-gene expression in occurrence of diabetes in obese rats.
Diabetes 1990;39(9):1050-6.
1990: Yamamoto T; Seino Y; Fukumoto H; Koh G; Yano H; Inagaki N; Yamada Y; Inoue K; Manabe T; Imura H
Over-expression of facilitative glucose transporter genes in human cancer.
Biochemical and biophysical research communications 1990;170(1):223-30.
1990: Yano H; Seino Y
[Motilin--structure and tissue specific expression of the human motilin gene and motilin receptor]
Nippon rinsho. Japanese journal of clinical medicine 1990;48(5):1005-10.
1990: Yamada Y; Seino Y; Takeda J; Fukumoto H; Yano H; Inagaki N; Fukuda Y; Seino S; Imura H
Increase in liver glucose transporter mRNA levels during rat liver regeneration.
Biochemical and biophysical research communications 1990;168(3):1274-9.
1990: Seino Y
[Plasma pancreatic polypeptide assay and the clinical significance]
Nippon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():40-2.
1990: Kurose T; Seino Y; Nishi S; Tsuji K; Taminato T; Tsuda K; Imura H
Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion.
The American journal of physiology 1990;258(1 Pt 1):E220-7.
1989: Inagaki N; Seino Y; Takeda J; Yano H; Yamada Y; Bell G I; Eddy R L; Fukushima Y; Byers M G; Shows T B
Gastric inhibitory polypeptide: structure and chromosomal localization of the human gene.
Molecular endocrinology (Baltimore, Md.) 1989;3(6):1014-21.
1989: Yano H; Seino Y; Fujita J; Yamada Y; Inagaki N; Takeda J; Bell G I; Eddy R L; Fan Y S; Byers M G
Exon-intron organization, expression, and chromosomal localization of the human motilin gene.
FEBS letters 1989;249(2):248-52.
1989: Takeda J; Ishii S; Seino Y; Imamoto F; Imura H
Negative regulation of human insulin gene expression by the 5'-flanking region in non-pancreatic cells.
FEBS letters 1989;247(1):41-5.
1989: Koh G; Seino Y; Takeda J; Fukumoto H; Kurose T; Tsuji K; Tsuda K; Taminato T; Imura H
Short term effects of glucose and arginine on the preproinsulin messenger ribonucleic acid level in the perfused rat pancreas: comparison with insulin secretion.
Endocrinology 1989;124(2):707-11.
1989: Takeshita N; Seino Y; Ishida H; Seino Y; Tanaka H; Tsutsumi C; Ogata K; Kiyohara K; Kato H; Nozawa M
Increased circulating levels of gamma-carboxyglutamic acid-containing protein and decreased bone mass in children on anticonvulsant therapy.
Calcified tissue international 1989;44(2):80-5.
1988: Kosaki A; Kuzuya H; Yoshimasa Y; Yamada K; Okamoto M; Nishimura H; Kakehi T; Takeda J; Seino Y; Imura H
Regulation of glucose-transporter gene expression by insulin in cultured human fibroblasts.
Diabetes 1988;37(11):1583-6.
1988: Ishida H; Seino Y; Taminato T; Usami M; Takeshita N; Seino Y; Tsutsumi C; Moriuchi S; Akiyama Y; Hara K
Circulating levels and bone contents of bone gamma-carboxyglutamic acid-containing protein are decreased in streptozocin-induced diabetes. Possible marker for diabetic osteopenia.
Diabetes 1988;37(6):702-6.
1988: Seno M; Seino Y; Taminato T; Tsuda K; Kitano N; Takeda J; Fukumoto H; Koh G; Imura H
Comparative effect of somatostatin-14 and somatostatin-28 on glucagon-induced glycogenolysis from the perfused rat liver.
Metabolism: clinical and experimental 1988;37(6):587-90.
1988: Kitano N; Taminato T; Ida T; Seno M; Seino Y; Matsukura S; Kuno S; Imura H
Detection of antibodies against wheat germ agglutinin bound glycoproteins on the islet-cell membrane.
Diabetic medicine : a journal of the British Diabetic Association 1988;5(2):139-44.
1988: Seno M; Tsuda K; Kitano N; Takeda J; Fukumoto H; Koh G; Imura H; Taminato T; Seino Y
Degradation and conversion of somatostatin in normal and diabetic rats in vivo and in vitro.
Canadian journal of physiology and pharmacology 1988;66(1):55-60.
1988: Usami M; Seino Y; Taminato T; Seno M; Koh G; Ohno M; Ikeda M; Imura H
Effect of DG5128 on epinephrine and glucagon induced glucose output from the isolated perfused rat liver.
Life sciences 1988;42(2):129-36.
1988: Kurose T; Seino Y; Ishida H; Tsuji K; Fukumoto H; Koh G; Takeda J; Kitano N; Inagaki N; Tsuda K
Effect of vitamin D on gastrin and gastric somatostatin secretion from the isolated perfused rat stomach.
Life sciences 1988;42(20):1995-2001.
1987: Seino Y; Tanaka K; Takeda J; Takahashi H; Mitani T; Kurono M; Kayano T; Koh G; Fukumoto H; Yano H
Sequence of an intestinal cDNA encoding human motilin precursor.
FEBS letters 1987;223(1):74-6.
1987: Takeda J; Seino Y; Tanaka K; Fukumoto H; Kayano T; Takahashi H; Mitani T; Kurono M; Suzuki T; Tobe T
Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7005-8.
1987: Nishi S; Seino Y; Kitano N; Seno M; Tsuji K; Kurose T; Taminato T; Tsuda K; Yanaihara C; Yanaihara N
Effects of naloxone on basal and vagus nerve-induced secretions of GRP, gastrin, and somatostatin from the isolated perfused rat stomach.
Life sciences 1987;41(15):1787-93.
1986: Fukumoto H; Seino Y; Koh G; Takeda J; Tsuji K; Kurose T; Kitano N; Tsuda K; Taminato T; Imura H
Effects of oral glucose administration on preproinsulin mRNA in rats in vivo.
Biochemical and biophysical research communications 1986;141(3):1201-6.
1985: Shima M; Seino Y; Tanaka Y; Yabuuchi H; Tsutsumi C; Moriuchi S
Bone gamma-carboxyglutamic acid containing protein in the perinatal period.
Acta paediatrica Scandinavica 1985;74(5):674-7.
1985: Ishida H; Seino Y; Nishi S; Kitano N; Seno M; Taminato T; Matsukura S; Ishizuka S; Imura H
Effects of insulin on altered mineral and vitamin D metabolism in streptozotocin-induced diabetes.
Acta endocrinologica 1985;108(2):231-6.
1985: Seno M; Seino Y; Takemura Y; Nishi S; Ishida H; Kitano N; Imura H; Taminato T; Matsukura S
Comparison of somatostatin-28 and somatostatin-14 clearance by the perfused rat liver.
Canadian journal of physiology and pharmacology 1985;63(1):62-7.
1984: Kurose T; Seino Y; Ishida H; Fujita J; Taminato T; Matsukura M; Imura H
Successful treatment of metastatic glucagonoma with dacarbazine.
Lancet 1984;1(8377):621-2.

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