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Terrence Blaschke

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Concepts & Ideas

Drug Dose-Response Relationship

Anatomy

Veins
Hand

Disorders

Chemicals & Drugs

Physiology

Pharmacokinetics

Activities & Behaviors

Patient Compliance

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Co-Publications
Name
37
Hoffman, Brian
12
Sheiner, Lewis
9
Tangphao, O
9
Kastrissios, H
9
Chalon, S
7
Moreno, HJ
5
Abiose, Ademola
4
Aweeka, Francesca
4
Verotta, Davide
4
Washington, Carla
3
Rosenkranz, Susan
3
Urae, A
3
Chan, Jonah
3
Cooke, John
2
Chao, Nelson

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Publications

TOP 3
Blaschke Terrence F
Variable adherence to prescribed dosing regimens for protease inhibitors: scope and outcomes.
Abiose Ademola K; Aronow Wilbert S; Moreno Heitor; Nair Chandra K; Blaschke Terrence F; Hoffman Brian B
Increased vascular alpha1-adrenergic sensitivity in patients with renal failure: receiving recombinant erythropoeitin.
Kshirsagar Smita A; Blaschke Terrence F; Sheiner Lewis B; Krygowski M; Acosta Edward P; Verotta Davide
Improving data reliability using a non-compliance detection method versus using pharmacokinetic criteria.

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All Publications

2008: Blaschke Terrence F
Variable adherence to prescribed dosing regimens for protease inhibitors: scope and outcomes.
Current opinion in HIV and AIDS 2008;3(6):603-7.
2007: Abiose Ademola K; Aronow Wilbert S; Moreno Heitor; Nair Chandra K; Blaschke Terrence F; Hoffman Brian B
Increased vascular alpha1-adrenergic sensitivity in patients with renal failure: receiving recombinant erythropoeitin.
American journal of therapeutics 2007;14(5):427-34.
2007: Kshirsagar Smita A; Blaschke Terrence F; Sheiner Lewis B; Krygowski M; Acosta Edward P; Verotta Davide
Improving data reliability using a non-compliance detection method versus using pharmacokinetic criteria.
Journal of pharmacokinetics and pharmacodynamics 2007;34(1):35-55.
2006: Motoya T; Thevanayagam L N; Blaschke T F; Au S; Stone J A; Jayewardene A L; Chi J; Aweeka F T
Characterization of nelfinavir binding to plasma proteins and the lack of drug displacement interactions.
HIV medicine 2006;7(2):122-8.
2004: Gandhi Monica; Aweeka Francesca; Greenblatt Ruth M; Blaschke Terrence F
Sex differences in pharmacokinetics and pharmacodynamics.
Annual review of pharmacology and toxicology 2004;44():499-523.
2003: Boffito Marta; Back David J; Blaschke Terrence F; Rowland Malcolm; Bertz Richard J; Gerber John G; Miller Veronica
Protein binding in antiretroviral therapies.
AIDS research and human retroviruses 2003;19(9):825-35.
2003: Washington Carla B; Flexner Charles; Sheiner Lewis B; Rosenkranz Susan L; Segal Yoninah; Aberg Judith A; Blaschke Terrence F;
Effect of simultaneous versus staggered dosing on pharmacokinetic interactions of protease inhibitors.
Clinical pharmacology and therapeutics 2003;73(5):406-16.
2002: Lu Jian-Feng; Blaschke Terrence F; Flexner Charles; Rosenkranz Susan L; Sheiner Lewis B;
Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1455-61.
2002: Fichtenbaum Carl J; Gerber John G; Rosenkranz Susan L; Segal Yoninah; Aberg Judith A; Blaschke Terrence; Alston Beverly; Fang Fang; Kosel Bradley; Aweeka Francesca;
Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047.
AIDS (London, England) 2002;16(4):569-77.
2002: Herforth Claudia; Stone Judith A; Jayewardene Anura L; Blaschke Terrence F; Fang Fang; Motoya Toshiro; Aweeka Francesca T
Determination of nelfinavir free drug concentrations in plasma by equilibrium dialysis and liquid chromatography/tandem mass spectrometry: important factors for method optimization.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(2):185-95.
2000: Washington C B; Wiltshire H R; Man M; Moy T; Harris S R; Worth E; Weigl P; Liang Z; Hall D; Marriott L; Blaschke T F
The disposition of saquinavir in normal and P-glycoprotein deficient mice, rats, and in cultured cells.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(9):1058-62.
2000: Chalon S; Moreno H; Benowitz N L; Hoffman B B; Blaschke T F
Nicotine impairs endothelium-dependent dilatation in human veins in vivo.
Clinical pharmacology and therapeutics 2000;67(4):391-7.
2000: Chan J R; Böger R H; Bode-Böger S M; Tangphao O; Tsao P S; Blaschke T F; Cooke J P
Asymmetric dimethylarginine increases mononuclear cell adhesiveness in hypercholesterolemic humans.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):1040-6.
2000: Zhang L; Gorset W; Washington C B; Blaschke T F; Kroetz D L; Giacomini K M
Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(3):329-34.
2000: Duchna H W; Guilleminault C; Stoohs R A; Faul J L; Moreno H; Hoffman B B; Blaschke T F
Vascular reactivity in obstructive sleep apnea syndrome.
American journal of respiratory and critical care medicine 2000;161(1):187-91.
1999: Tangphao O; Chalon S; Moreno H J; Abiose A K; Blaschke T F; Hoffman B B
Heparin-induced vasodilation in human hand veins.
Clinical pharmacology and therapeutics 1999;66(3):232-8.
1999: Tangphao O; Grossmann M; Chalon S; Hoffman B B; Blaschke T F
Pharmacokinetics of intravenous and oral L-arginine in normal volunteers.
British journal of clinical pharmacology 1999;47(3):261-6.
1999: Chalon S; Moreno H; Hoffman B B; Blaschke T F
Angiotensin-converting enzyme inhibition improves venous endothelial dysfunction in chronic smokers.
Clinical pharmacology and therapeutics 1999;65(3):295-303.
1999: Tangphao O; Chalon S; Moreno H; Hoffman B B; Blaschke T F
Pharmacokinetics of L-arginine during chronic administration to patients with hypercholesterolaemia.
Clinical science (London, England : 1979) 1999;96(2):199-207.
1999: Chalon S; Tejura B; Moreno H; Urae A; Blaschke T F; Hoffman B B
Role of nitric oxide in isoprenaline and sodium nitroprusside-induced relaxation in human hand veins.
British journal of clinical pharmacology 1999;47(1):91-8.
1999: Chalon S; Bedarida G V; Moreno H; Tejura B; Urae A; Hoffman B B; Blaschke T F
Inhibition of angiotensin-converting enzyme in human hand veins.
Clinical pharmacology and therapeutics 1999;65(1):58-65.
1999: Tangphao O; Chalon S; Coulston A M; Moreno H; Chan J R; Cooke J P; Hoffman B B; Blaschke T F
L-arginine and nitric oxide-related compounds in plasma: comparison of normal and arginine-free diets in a 24-h crossover study.
Vascular medicine (London, England) 1999;4(1):27-32.
1998: Kastrissios H; Suárez J R; Hammer S; Katzenstein D; Blaschke T F
The extent of non-adherence in a large AIDS clinical trial using plasma dideoxynucleoside concentrations as a marker.
AIDS (London, England) 1998;12(17):2305-11.
1998: Kastrissios H; Suárez J R; Katzenstein D; Girard P; Sheiner L B; Blaschke T F
Characterizing patterns of drug-taking behavior with a multiple drug regimen in an AIDS clinical trial.
AIDS (London, England) 1998;12(17):2295-303.
1998: Washington C B; Duran G E; Man M C; Sikic B I; Blaschke T F
Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;19(3):203-9.
1998: Böger R H; Bode-Böger S M; Szuba A; Tsao P S; Chan J R; Tangphao O; Blaschke T F; Cooke J P
Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia.
Circulation 1998;98(18):1842-7.
1998: Girard P; Blaschke T F; Kastrissios H; Sheiner L B
A Markov mixed effect regression model for drug compliance.
Statistics in medicine 1998;17(20):2313-33.
1998: Moreno H; Chalon S; Urae A; Tangphao O; Abiose A K; Hoffman B B; Blaschke T F
Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation.
The American journal of physiology 1998;275(3 Pt 2):H1040-5.
1997: Vanhove G F; Gries J M; Verotta D; Sheiner L B; Coombs R; Collier A C; Blaschke T F
Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy.
Antimicrobial agents and chemotherapy 1997;41(11):2433-8.
1997: Vanhove G F; Kastrissios H; Gries J M; Verotta D; Park K; Collier A C; Squires K; Sheiner L B; Blaschke T F
Pharmacokinetics of saquinavir, zidovudine, and zalcitabine in combination therapy.
Antimicrobial agents and chemotherapy 1997;41(11):2428-32.
1997: Park K; Verotta D; Blaschke T F; Sheiner L B
A semiparametric method for describing noisy population pharmacokinetic data.
Journal of pharmacokinetics and biopharmaceutics 1997;25(5):615-42.
1997: Abiose A K; Grossmann M; Tangphao O; Hoffman B B; Blaschke T F
Chloroquine-induced venodilation in human hand veins.
Clinical pharmacology and therapeutics 1997;61(6):677-83.
1997: Kastrissios H; Blaschke T F
Medication compliance as a feature in drug development.
Annual review of pharmacology and toxicology 1997;37():451-75.
1996: Grossmann M; Abiose A; Tangphao O; Blaschke T F; Hoffman B B
Morphine-induced venodilation in humans.
Clinical pharmacology and therapeutics 1996;60(5):554-60.
1996: Girard P; Sheiner L B; Kastrissios H; Blaschke T F
Do we need full compliance data for population pharmacokinetic analysis?
Journal of pharmacokinetics and biopharmaceutics 1996;24(3):265-82.
1996: Kastrissios H; Flowers N T; Blaschke T F
Introducing medical students to medication noncompliance.
Clinical pharmacology and therapeutics 1996;59(5):577-82.
1996: Blaschke T F; Skinner M H
The clinical pharmacokinetics of rifabutin.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;22 Suppl 1():S15-21; discussion S21-2.
1996: Kastrissios H; Chao N J; Blaschke T F
Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients.
Cancer chemotherapy and pharmacology 1996;38(5):425-30.
1995: Bedarida G; Bushell E; Blaschke T F; Hoffman B B
H1- and H2-histamine receptor-mediated vasodilation varies with aging in humans.
Clinical pharmacology and therapeutics 1995;58(1):73-80.
1995: Chao N J; Kastrissios H; Long G D; Negrin R S; Horning S J; Wong R M; Blaschke T F; Blume K G
A new preparatory regimen for autologous bone marrow transplantation for patients with lymphoma.
Cancer 1995;75(6):1354-9.
1995: Ford G A; Dachman W D; Blaschke T F; Hoffman B B
Effect of aging on beta 2-adrenergic receptor-stimulated flux of K+, PO4, FFA, and glycerol in human forearms.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(1):172-8.
1994: Dachman W D; Bedarida G; Blaschke T F; Hoffman B B
Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes.
The Journal of allergy and clinical immunology 1994;93(3):606-14.
1994: Bedarida G V; Kim D; Blaschke T F; Hoffman B B
Characterization of an inhibitor of nitric oxide synthase in human-hand veins.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1994;26(2):109-12.
1993: Bedarida G V; Bushell E; Haefeli W E; Blaschke T F; Hoffman B B
Responsiveness to bradykinin in veins of hypercholesterolemic humans.
Circulation 1993;88(6):2754-61.
1993: Bedarida G; Kim D; Blaschke T F; Hoffman B B
Venodilation in Raynaud's disease.
Lancet 1993;342(8885):1451-4.
1993: Sale M; Sheiner L B; Volberding P; Blaschke T F
Zidovudine response relationships in early human immunodeficiency virus infection.
Clinical pharmacology and therapeutics 1993;54(5):556-66.
1993: Lenert L A; Markowitz D R; Blaschke T F
Primum non nocere? Valuing of the risk of drug toxicity in therapeutic decision making.
Clinical pharmacology and therapeutics 1993;53(3):285-91.
1993: Dachman W D; Ford G A; Blaschke T F; Hoffman B B
Mechanism of bradykinin-induced venodilation in humans.
Journal of cardiovascular pharmacology 1993;21(2):241-8.
1992: Haefeli W E; Gumbleton M; Benet L Z; Hoffman B B; Blaschke T F
Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins.
Clinical pharmacology and therapeutics 1992;52(6):590-6.
1992: Vincent J; Kongpatanakul S; Blaschke T F; Hoffman B B
Desensitization of nitrate-induced venodilation: reversal with oral N-acetylcysteine in humans.
Journal of cardiovascular pharmacology 1992;20(6):907-12.
1992: Vincent J; Dachman W; Blaschke T F; Hoffman B B
Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans.
The Journal of clinical investigation 1992;90(5):1763-8.
1992: Dachman W D; Ford G A; Hoffman B B; Blaschke T F
Bradykinin-induced venodilation is not impaired with aging in humans.
Journal of gerontology 1992;47(5):M166-70.
1992: Lenert L A; Klostermann H; Coleman R W; Lurie J; Blaschke T F
Practical computer-assisted dosing for aminoglycoside antibiotics.
Antimicrobial agents and chemotherapy 1992;36(6):1230-5.
1992: Vincent J; Blaschke T F; Hoffman B B
Desensitization of beta-adrenoceptor- and prostaglandin E1 receptor-mediated human vascular smooth muscle relaxation.
Journal of cardiovascular pharmacology 1992;19(3):447-52.
1992: Lenert L A; Lurie J; Sheiner L B; Coleman R; Klostermann H; Blaschke T F
Advanced computer programs for drug dosing that combine pharmacokinetic and symbolic modeling of patients.
Computers and biomedical research, an international journal 1992;25(1):29-42.
1992: Eichler H G; Blaschke T F; Kraemer F B; Ford G A; Blöchl-Daum B; Hoffman B B
Responsiveness of superficial hand veins to alpha-adrenoceptor agonists in insulin-dependent diabetic patients.
Clinical science (London, England : 1979) 1992;82(2):163-8.
1992: Vincent J; Blaschke T F; Hoffman B B
Vascular reactivity to phenylephrine and angiotensin II: comparison of direct venous and systemic vascular responses.
Clinical pharmacology and therapeutics 1992;51(1):68-75.
1992: Ford G A; Hoffman B B; Blaschke T F
Beta adrenergically mediated cardiac chronotropic and vascular smooth muscle responses during propranolol therapy and withdrawal in young and elderly persons.
Journal of gerontology 1992;47(1):M22-6.
1992: Ford G A; Hoffman B B; Vestal R E; Blaschke T F
Age-related changes in adenosine and beta-adrenoceptor responsiveness of vascular smooth muscle in man.
British journal of clinical pharmacology 1992;33(1):83-7.
1991: Ford G A; Katzir D; Blaschke T F; Hoffman B B
Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension.
Clinical pharmacology and therapeutics 1991;50(2):192-8.
1990: Leemann T D; Blaschke T F
Semi-quantitative simulation for reasoning about physiological models of drug kinetics and effects.
Schweizerische medizinische Wochenschrift 1990;120(49):1849-52.
1990: Eichler H G; Blaschke T F; Hoffman B B
Decreased responsiveness of superficial hand veins to phenylephrine in black normotensive males.
Journal of cardiovascular pharmacology 1990;16(2):177-81.
1990: Blaschke T F
Research and the American Society for Clinical Pharmacology and Therapeutics.
Clinical pharmacology and therapeutics 1990;47(2):270-2.
1990: Ford G A; Hoffman B B; Blaschke T F
Effect of temazepam on blood pressure regulation in healthy elderly subjects.
British journal of clinical pharmacology 1990;29(1):61-7.
1989: Blaschke T F
Clinical pharmacology comes of age.
Clinical pharmacology and therapeutics 1989;46(5):485-8.
1989: Lenert L; Sheiner L; Blaschke T
Improving drug dosing in hospitalized patients: automated modeling of pharmacokinetics for individualization of drug dosage regimens.
Computer methods and programs in biomedicine 1989;30(2-3):169-76.
1989: Hiremath A N; Hoffman B B; Blaschke T F
Responsiveness of peripheral veins to transdermal and sublingual nitroglycerin in healthy male volunteers.
Journal of cardiovascular pharmacology 1989;14(4):534-41.
1989: Atiba J O; Blaschke T F; Wilkinson G R
Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine.
British journal of clinical pharmacology 1989;28(2):161-5.
1989: Skinner M H; Hsieh M; Torseth J; Pauloin D; Bhatia G; Harkonen S; Merigan T C; Blaschke T F
Pharmacokinetics of rifabutin.
Antimicrobial agents and chemotherapy 1989;33(8):1237-41.
1989: Torseth J; Bhatia G; Harkonen S; Child C; Skinner M; Robinson W S; Blaschke T F; Merigan T C
Evaluation of the antiviral effect of rifabutin in AIDS-related complex.
The Journal of infectious diseases 1989;159(6):1115-8.
1989: Eichler H G; Eichler I; Lewiston N; Blaschke T F; Hoffman B B
Responsiveness of superficial hand veins to adrenergic stimuli in patients with cystic fibrosis.
Clinical science (London, England : 1979) 1989;76(3):283-7.
1989: Eichler H G; Ford G A; Blaschke T F; Swislocki A; Hoffman B B
Responsiveness of superficial hand veins to phenylephrine in essential hypertension. Alpha adrenergic blockade during prazosin therapy.
The Journal of clinical investigation 1989;83(1):108-12.
1988: Ford G A; Eichler H G; Hoffman B B; Blaschke T F
Venous responsiveness to atrial natriuretic factor in man.
British journal of clinical pharmacology 1988;26(6):797-9.
1987: Eichler H G; Hiremath A; Katzir D; Blaschke T F; Hoffman B B
Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans.
Clinical pharmacology and therapeutics 1987;42(5):521-4.
1987: Anderson J E; Morris R E; Blaschke T F
Ketoconazole potentiates cyclosporine immunosuppression and toxicity in mice.
Transplantation proceedings 1987;19(1 Pt 2):1267-8.

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