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Jacob Selhub

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Ligi Paul; Per Magne Ueland; Jacob Selhub
Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation.
Youjin Je; Jung Eun Lee; Jing Ma; Jeffrey Meyerhardt; Bernard Rosner; Jacob Selhub; Xuehong Zhang; Eunyoung Cho; Charles S Fuchs; Edward Giovannucci
Prediagnostic plasma vitamin B6 (pyridoxal 5'-phosphate) and survival in patients with colorectal cancer.
Hongmei Nan; Ligi Paul; Bernard Rosner; Jacob Selhub; Kana Wu; Charles S Fuchs; Edward L Giovannucci; Eunyoung Cho
Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.

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All Publications

2013: Ligi Paul; Per Magne Ueland; Jacob Selhub
Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation.
Nutrition reviews 2013;71(4):239-44.
2013: Youjin Je; Jung Eun Lee; Jing Ma; Jeffrey Meyerhardt; Bernard Rosner; Jacob Selhub; Xuehong Zhang; Eunyoung Cho; Charles S Fuchs; Edward Giovannucci
Prediagnostic plasma vitamin B6 (pyridoxal 5'-phosphate) and survival in patients with colorectal cancer.
Cancer causes & control : CCC 2013;24(4):719-29.
2013: Hongmei Nan; Ligi Paul; Bernard Rosner; Jacob Selhub; Kana Wu; Charles S Fuchs; Edward L Giovannucci; Eunyoung Cho
Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.
PloS one 2013;8(4):e59455.
2013: Leonie G Mikael; Ligi Paul; Liyuan Deng; Jacob Selhub; Rima Rozen
Moderately high intake of folic acid has a negative impact on mouse embryonic development.
Birth defects research. Part A, Clinical and molecular teratology 2013;97(1):47-52.
2012: Manuela A Orjuela; Ligi Paul; Marco A Ramirez-Ortiz; Jacob Selhub; Ida H Suen; Lourdes Cabrera-Muñoz; Jia Chen; Silvia Diaz-Carreño; Xinhua Liu; Aurora Medina-Sanson; Fabiola Mejia-Rodriguez; M Veronica Ponce-Castañeda
Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake.
Cancer 2012;118(23):5912-9.
2012: Yiqing Song; Nancy R Cook; Edward Giovannucci; I-Min Lee; JoAnn E Manson; Ligi Paul; Jacob Selhub; Shumin M Zhang
Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma.
Journal of the National Cancer Institute 2012;104(20):1562-75.
2012: Martha Savaria Morris; Jacob Selhub; Paul F Jacques
Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study.
Journal of the American Geriatrics Society 2012;60(8):1457-64.
2012: Denish Moorthy; José M Ordovás; Laurence D Parnell; Inga Peter; Irwin H Rosenberg; Tammy M Scott; Jacob Selhub; Jimmy W Crott; John Griffith; Chao-Qiang Lai; Katherine L Tucker; Aron Troen
Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults.
The Journal of nutrition 2012;142(8):1554-60.
2012: Lydia Sakakeeny; Emelia J Benjamin; Yoram Bujanover; Joao D Fontes; Paul F Jacques; Martin Obin; Ronenn Roubenoff; Jacob Selhub
Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults.
The Journal of nutrition 2012;142(7):1280-5.
2012: David Mischoulon; Andrew A Nierenberg; George I Papakostas; Jacob Selhub; Albert S Yeung; Jonathan E Alpert; Lee Baer; Alisabet J Clain; Christina M Dording; Amy H Farabaugh; Dan V Iosifescu; Judith Katz; Stefania Lamon-Fava; Maurizio Fava
Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment.
CNS spectrums 2012;17(2):76-86.
2012: Aleksandra Pikula; Jacob Selhub; Geoffrey H Toffler; Ramachandran S Vasan; Thomas J Wang; Philip A Wolf; Rhoda Au; Alexa Beiser; Stéphanie Debette; Charles DeCarli; Jayandra J Himali; Carlos S Kase; Margaret Kelly-Hayes; James B Meigs; Sudha Seshadri
Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
Circulation 2012;125(17):2100-7.
2012: Jung Eun Lee; Jing Ma; Jacob Selhub; Meir J Stampfer; Esther K Wei; Walter C Willett; Charles S Fuchs; David J Hunter; I-Min Lee; Edward Giovannucci
Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies.
Cancer causes & control : CCC 2012;23(4):537-45.
2012: Summer S Han; Philip S Rosenberg; Jacob Selhub; Laura Y Sue; Sonja I Berndt; Laurie A Burdette; Regina G Ziegler
Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012;21(3):417-27.
2012: Aron Troen; Daniel E Weiner; Gerard Dallal; Kristen E D'Anci; Beverly Dobson; Paul F Jacques; Andrew S Levey; Denish Moorthy; Gail Rogers; Irwin H Rosenberg; Tammy M Scott; Jacob Selhub
Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT).
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2012;22(2):268-76.e1-3.
2012: Giuseppina T Russo; Francesco Squadrito; Maria Francesca Stagno; E Alessi; Domenica Altavilla; Alessandra Bitto; Domenico Cucinotta; Annalisa Giandalia; Letteria Minutoli; Elisabetta L Romeo; Jacob Selhub
Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.
Journal of nutrition and metabolism 2012;2012():132056.
2011: Ji Zhang; Guylaine Bouchard; Diane E Handy; Joseph Loscalzo; Jacob Selhub; Yufang Wang; Martin C Carey
Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice.
Hepatology (Baltimore, Md.) 2011;54(2):697-706.
2011: Jacob Selhub; Ligi Paul
Folic acid fortification: why not vitamin B12 also?
BioFactors (Oxford, England) 2011;37(4):269-71.
2011: Renee Kalmbach; Ligi Paul; Jacob Selhub
Determination of unmetabolized folic acid in human plasma using affinity HPLC.
The American journal of clinical nutrition 2011;94(1):343S-347S.
2011: Loïc Le Marchand; Hansong Wang; Jacob Selhub; Thomas M Vogt; Lance Yokochi; Robert Decker
Association of plasma vitamin B6 with risk of colorectal adenoma in a multiethnic case-control study.
Cancer causes & control : CCC 2011;22(6):929-36.
2011: Gwen Murphy; Jin-Hu Fan; Steven D Mark; Sanford M Dawsey; Jacob Selhub; Jianbing Wang; Philip R Taylor; You-Lin Qiao; Christian C Abnet
Prospective study of serum cysteine levels and oesophageal and gastric cancers in China.
Gut 2011;60(5):618-23.
2011: Fernando Sempértegui; Bertha Estrella; Katherine L Tucker; Davidson H Hamer; Ximena Narvaez; Mercy Sempértegui; Jeffrey K Griffiths; Sabrina E Noel; Gerard Dallal; Jacob Selhub; Simin Nikbin Meydani
Metabolic syndrome in the elderly living in marginal peri-urban communities in Quito, Ecuador.
Public health nutrition 2011;14(5):758-67.
2011: Andrew G Bostom; Myra A Carpenter; John W Kusek; Andrew S Levey; Lawrence Hunsicker; Marc A Pfeffer; Jacob Selhub; Paul F Jacques; Edward Cole; Lisa Gravens-Mueller; Andrew A House; Clifton Kew; Joyce L McKenney; Alvaro Pacheco-Silva; Todd Pesavento; John Pirsch; Stephen Smith; Scott Solomon; Matthew R Weir
Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial.
Circulation 2011;123(16):1763-70.
2011: Marion Dietrich; Paul F Jacques; Joseph F Polak; Michelle J Keyes; Michael J Pencina; Jane C Evans; Philip A Wolf; Jacob Selhub; Ramachandran S Vasan; Ralph B D'Agostino
Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2011;20(2):155-61.
2011: Laura Pickell; Katharine Brown; Deqiang Li; Xiao-Ling Wang; Liyuan Deng; Qing Wu; Jacob Selhub; Li Luo; Loydie Jerome-Majewska; Rima Rozen
High intake of folic acid disrupts embryonic development in mice.
Birth defects research. Part A, Clinical and molecular teratology 2011;91(1):8-19.
2010: Jacob Selhub; Aron Troen; Irwin H Rosenberg
B vitamins and the aging brain.
Nutrition reviews 2010;68 Suppl 2():S112-8.
2010: Caroline S Fox; Philimon Gona; Martin G Larson; Jacob Selhub; Geoffrey Tofler; Shih-Jen Hwang; James B Meigs; Daniel Levy; Thomas J Wang; Paul F Jacques; Emelia J Benjamin; Ramachandran S Vasan
A multi-marker approach to predict incident CKD and microalbuminuria.
Journal of the American Society of Nephrology : JASN 2010;21(12):2143-9.
2010: Raghava S Velagaleti; Philimon Gona; Martin G Larson; Thomas J Wang; Daniel Levy; Emelia J Benjamin; Jacob Selhub; Paul F Jacques; James B Meigs; Geoffrey H Tofler; Ramachandran S Vasan
Multimarker approach for the prediction of heart failure incidence in the community.
Circulation 2010;122(17):1700-6.
2010: Todd M Gibson; Stephanie J Weinstein; Susan T Mayne; Ruth M Pfeiffer; Jacob Selhub; Philip R Taylor; Jarmo Virtamo; Demetrius Albanes; Rachael Stolzenberg-Solomon
A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma.
Cancer causes & control : CCC 2010;21(7):1061-9.
2010: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
The American journal of clinical nutrition 2010;91(6):1733-44.
2010: John H Page; Jing Ma; Stephanie E Chiuve; Meir J Stampfer; Jacob Selhub; JoAnn E Manson; Eric B Rimm
Plasma total cysteine and total homocysteine and risk of myocardial infarction in women: a prospective study.
American heart journal 2010;159(4):599-604.
2010: Jennifer Lin; I-Min Lee; Yiqing Song; Nancy R Cook; Jacob Selhub; JoAnn E Manson; Julie E Buring; Shumin M Zhang
Plasma homocysteine and cysteine and risk of breast cancer in women.
Cancer research 2010;70(6):2397-405.
2010: Renate B Schnabel; Martin G Larson; Jennifer F Yamamoto; Lisa M Sullivan; Michael J Pencina; James B Meigs; Geoffrey H Tofler; Jacob Selhub; Paul F Jacques; Philip A Wolf; Jared W Magnani; Patrick T Ellinor; Thomas J Wang; Daniel Levy; Ramachandran S Vasan; Emelia J Benjamin
Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community.
Circulation 2010;121(2):200-7.
2010: Aditi Hazra; Jacob Selhub; Wei-Hsun Chao; Per Magne Ueland; David J Hunter; John A Baron
Uracil misincorporation into DNA and folic acid supplementation.
The American journal of clinical nutrition 2010;91(1):160-5.
2010: Martha Savaria Morris; Lydia Sakakeeny; Paul F Jacques; Mary Frances Picciano; Jacob Selhub
Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status.
The Journal of nutrition 2010;140(1):103-10.
2009: Kana Wu; Elizabeth A Platz; Walter C Willett; Charles S Fuchs; Jacob Selhub; Bernard A Rosner; David J Hunter; Edward Giovannucci
A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma.
The American journal of clinical nutrition 2009;90(6):1623-31.
2009: Aditi Hazra; Peter Kraft; Ross Lazarus; Constance Chen; STEPHEN CHANOCK; Paul Jacques; Jacob Selhub; David J Hunter
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
Human molecular genetics 2009;18(23):4677-87.
2009: Stephanie J Weinstein; Katrina Mackrain; Rachael Stolzenberg-Solomon; Jacob Selhub; Jarmo Virtamo; Demetrius Albanes
Serum creatinine and prostate cancer risk in a prospective study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(10):2643-9.
2009: John H Page; Jing Ma; Stephanie E Chiuve; Meir J Stampfer; Jacob Selhub; JoAnn E Manson; Eric B Rimm
Plasma vitamin B(6) and risk of myocardial infarction in women.
Circulation 2009;120(8):649-55.
2009: Ligi Paul; Marco Cattaneo; Armando D'Angelo; Francesca Sampietro; Isabella Fermo; Cristina Razzari; Gessica Fontana; Nindra Eugene; Paul F Jacques; Jacob Selhub
Telomere length in peripheral blood mononuclear cells is associated with folate status in men.
The Journal of nutrition 2009;139(7):1273-8.
2009: Helmut B Heseker; Joel B Mason; Jacob Selhub; Irwin H Rosenberg; Paul F Jacques
Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid.
The British journal of nutrition 2009;102(2):173-80.
2009: Jacob Joseph; Michael J Pencina; Thomas J Wang; Laura Hayes; Geoffrey H Tofler; Paul Jacques; Jacob Selhub; Daniel Levy; Ralph B D'Agostino; Emelia Benjamin; Ramachandran S Vasan
Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community.
Journal of hypertension 2009;27(6):1317-24.
2009: M Fayfman; Jingbo Niu; Yu Qing Zhang; David T Felson; Burton Sack; Piran Aliabadi; Jacob Selhub; David J Hunter
The relation of plasma homocysteine to radiographic knee osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(6):766-71.
2009: Jung Eun Lee; Haojie Li; Edward Giovannucci; I-Min Lee; Jacob Selhub; Meir Stampfer; Jing Ma
Prospective study of plasma vitamin B6 and risk of colorectal cancer in men.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(4):1197-202.
2009: Howard N Hodis; Wendy Mack; Laurie Dustin; Peter R Mahrer; Stanley P Azen; Robert Detrano; Jacob Selhub; Petar Alaupovic; Chao-ran Liu; Ci-hua Liu; Juliana Hwang; AG Wilcox; Robert H Selzer
High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial.
Stroke; a journal of cerebral circulation 2009;40(3):730-6.
2009: Jacob Selhub; Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
The American journal of clinical nutrition 2009;89(2):702S-6S.
2009: Wolfgang Lieb; Martin G Larson; Emelia Benjamin; Xiaoyan Yin; Geoffrey H Tofler; Jacob Selhub; Paul F Jacques; Thomas J Wang; Joseph A Vita; Daniel Levy; Ramachandran S Vasan; Gary F Mitchell
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study.
Circulation 2009;119(1):37-43.
2009: María Achón; Elena Alonso-Aperte; Gregorio Varela-Moreiras; Jacob Selhub
Mild methionine excess does not affect thymidylate synthesis or inflammation markers expression in human aortic endothelial cells.
Annals of nutrition & metabolism 2009;54(1):28-34.
2009: Davidson H Hamer; Fernando Sempértegui; Bertha Estrella; Katherine L Tucker; Alicia Rodríguez; Josefina Egas; Gerard Dallal; Jacob Selhub; Jeffrey Griffiths; Simin Nikbin Meydani
Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians.
The Journal of nutrition 2009;139(1):113-9.
2008: Aron Troen; Wei-Hsun Chao; Natalia Crivello; Kristen E D'Anci; Barbara Shukitt-Hale; Don E Smith; Jacob Selhub; Irwin H Rosenberg
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.
The Journal of nutrition 2008;138(12):2502-9.
2008: Renee D Kalmbach; Silvina F Choumenkovitch; Aron Troen; Paul F Jacques; Ralph D'Agostino; Jacob Selhub
A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate.
The Journal of nutrition 2008;138(12):2323-7.
2008: Peter W F Wilson; Michael Pencina; Paul Jacques; Jacob Selhub; Ralph D'Agostino; Christopher J O'Donnell
C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study.
Circulation. Cardiovascular quality and outcomes 2008;1(2):92-7.
2008: Stephanie J Weinstein; Demetrius Albanes; Jacob Selhub; Barry I Graubard; Unhee Lim; Philip R Taylor; Jarmo Virtamo; Rachael Stolzenberg-Solomon
One-carbon metabolism biomarkers and risk of colon and rectal cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(11):3233-40.
2008: Aditi Hazra; Peter Kraft; Jacob Selhub; Edward L Giovannucci; Gilles Thomas; Robert N Hoover; STEPHEN CHANOCK; David J Hunter
Common variants of FUT2 are associated with plasma vitamin B12 levels.
Nature genetics 2008;40(10):1160-2.
2008: Renee D Kalmbach; Silvina F Choumenkovitch; Aron Troen; Ralph D'Agostino; Paul F Jacques; Jacob Selhub
Circulating folic acid in plasma: relation to folic acid fortification.
The American journal of clinical nutrition 2008;88(3):763-8.
2008: Aron Troen; Melissa Shea-Budgell; Barbara Shukitt-Hale; Donald E Smith; Jacob Selhub; Irwin H Rosenberg
B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12474-9.
2008: Brian M Wolpin; Esther K Wei; Kimmie Ng; Jeffrey A Meyerhardt; Jennifer A Chan; Jacob Selhub; Edward L Giovannucci; Charlie S Fuchs
Prediagnostic plasma folate and the risk of death in patients with colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(19):3222-8.
2008: Jacob Selhub; Irwin H Rosenberg
Public health significance of supplementation or fortification of grain products with folic acid.
Food and nutrition bulletin 2008;29(2 Suppl):S173-6.
2008: Jacob Selhub
Public health significance of elevated homocysteine.
Food and nutrition bulletin 2008;29(2 Suppl):S116-25.
2008: Jacob Selhub; Paul F Jacques; Gerard Dallal; Silvina Choumenkovitch; Gail Rogers
The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status.
Food and nutrition bulletin 2008;29(2 Suppl):S67-73.
2008: Robert R McLean; Paul F Jacques; Jacob Selhub; Lisa Fredman; Katherine L Tucker; Elizabeth J Samelson; Douglas P Kiel; L Adrienne Cupples; Marian T Hannan
Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women.
The Journal of clinical endocrinology and metabolism 2008;93(6):2206-12.
2008: Sudha Seshadri; Philip A Wolf; Alexa Beiser; Jacob Selhub; Rhoda Au; Paul F Jacques; Mitsuhiro Yoshita; Irwin H Rosenberg; Ralph B D'Agostino; Charles DeCarli
Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.
Archives of neurology 2008;65(5):642-9.
2008: Martha Savaria Morris; Mary Frances Picciano; Paul F Jacques; Jacob Selhub
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004.
The American journal of clinical nutrition 2008;87(5):1446-54.
2008: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Correspondence: will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?
Pediatric research 2008;63(4):450; author reply 450-1.
2008: Jennifer Lin; I-Min Lee; Nancy R Cook; Jacob Selhub; JoAnn E Manson; Julie E Buring; Shumin M Zhang
Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women.
The American journal of clinical nutrition 2008;87(3):734-43.
2007: Jacob Selhub; Martha Savaria Morris; Paul F Jacques
In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19995-20000.
2007: Jennifer Lin; JoAnn E Manson; Jacob Selhub; Julie E Buring; Shumin M Zhang
Plasma cysteinylglycine levels and breast cancer risk in women.
Cancer research 2007;67(23):11123-7.
2007: Senada Arabelovic; Gina Sam; Gerard Dallal; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg; Ronenn Roubenoff
Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis.
Journal of the American College of Nutrition 2007;26(5):453-5.
2007: Erik Ingelsson; Michael J Pencina; Geoffrey H Tofler; Emelia Benjamin; Katherine J Lanier; Paul F Jacques; Caroline S Fox; James B Meigs; Daniel Levy; Martin G Larson; Jacob Selhub; Ralph B D'Agostino; Thomas J Wang; Ramachandran S Vasan
Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.
Circulation 2007;116(9):984-92.
2007: Joel B Mason; Aaron Dickstein; Paul F Jacques; Paul Haggarty; Jacob Selhub; Gerard Dallal; Irwin H Rosenberg
A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(7):1325-9.
2007: Daniel Levy; Shih-Jen Hwang; Atilla Kayalar; Emelia Benjamin; Ramachandran S Vasan; Helen Parise; Martin G Larson; Thomas J Wang; Jacob Selhub; Paul F Jacques; Joseph A Vita; Michelle J Keyes; Gary F Mitchell
Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study.
Circulation 2007;115(24):3079-85.
2007: Aron Troen; Emily E French; Jessica F Roberts; Jacob Selhub; Jose Ordovas; Laurence D Parnell; Chao-Qiang Lai
Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet.
Age (Dordrecht, Netherlands) 2007;29(1):29-39.
2007: Thomas J Wang; Philimon Gona; Martin G Larson; Daniel Levy; Emelia Benjamin; Geoffrey H Tofler; Paul F Jacques; James B Meigs; Nader Rifai; Jacob Selhub; Sander J Robins; Christopher Newton-Cheh; Ramachandran S Vasan
Multiple biomarkers and the risk of incident hypertension.
Hypertension 2007;49(3):432-8.
2007: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.
The American journal of clinical nutrition 2007;85(1):193-200.
2006: Thomas J Wang; Philimon Gona; Martin G Larson; Geoffrey H Tofler; Daniel Levy; Christopher Newton-Cheh; Paul F Jacques; Nader Rifai; Jacob Selhub; Sander J Robins; Emelia Benjamin; Ralph B D'Agostino; Ramachandran S Vasan
Multiple biomarkers for the prediction of first major cardiovascular events and death.
The New England journal of medicine 2006;355(25):2631-9.
2006: Rosalia Póo-Prieto; David B Haytowitz; Joanne M Holden; Gail Rogers; Silvina F Choumenkovitch; Paul F Jacques; Jacob Selhub
Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products.
The Journal of nutrition 2006;136(12):3079-83.
2006: Karin J A Lievers; Leo A J Kluijtmans; Henk J Blom; Peter W Wilson; Jacob Selhub; Jose Ordovas
Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study.
European journal of human genetics : EJHG 2006;14(10):1125-9.
2006: Aron Troen; Barbara Shukitt-Hale; Wei-Hsun Chao; Bina Albuquerque; Donald E Smith; Jacob Selhub; Jacob Rosenberg
The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice.
Journal of Alzheimer's disease : JAD 2006;9(4):381-92.
2006: Montserrat C Anguera; Martha S Field; Cheryll Perry; Haifa Ghandour; En-Pei Chiang; Jacob Selhub; Barry Shane; Patrick J Stover
Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase.
The Journal of biological chemistry 2006;281(27):18335-42.
2006: Jacob Selhub
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
The Journal of nutrition 2006;136(6 Suppl):1726S-1730S.
2006: Tammy M Scott; Inga Peter; Katherine L Tucker; Lisa Arsenault; Peter Bergethon; Rafeeque Bhadelia; Jennifer Buell; Lauren Collins; John F Dashe; John Griffith; Patricia L Hibberd; Drew Leins; Timothy Liu; Jose Ordovas; Samuel Patz; Lori Lyn Price; Wei Qiao Qiu; Mark J Sarnak; Jacob Selhub; Lauren Smaldone; Carey Wagner; Lixia Wang; Daniel Weiner; Jacqueline Yee; Irwin Rosenberg; MARSHAL FOLSTEIN
The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population.
International journal of geriatric psychiatry 2006;21(6):519-28.
2006: Eunyoung Cho; Steven H Zeisel; Paul Jacques; Jacob Selhub; Lauren Dougherty; GRaham Colditz; Walter C Willett
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
The American journal of clinical nutrition 2006;83(4):905-11.
2006: Vandana Menon; Mark J Sarnak; Tom Greene; Xuelei Wang; Arema A Pereira; Gerald J Beck; John W Kusek; Jacob Selhub; Allan J Collins; Andrew S Levey; Michael G Shlipak
Relationship between homocysteine and mortality in chronic kidney disease.
Circulation 2006;113(12):1572-7.
2006: Aron Troen; Breeana Mitchell; Bess Sorensen; Mark H Wener; Abbey Johnston; Brent Wood; Jacob Selhub; Anne McTiernan; Yutaka Yasui; Evrim Oral; John D Potter; Cornelia M Ulrich
Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women.
The Journal of nutrition 2006;136(1):189-94.
2005: Allon N Friedman; Lawrence G Hunsicker; Jacob Selhub; Andrew G Bostom
Total plasma homocysteine and arteriosclerotic outcomes in type 2 diabetes with nephropathy.
Journal of the American Society of Nephrology : JASN 2005;16(11):3397-402.
2005: Merrill F Elias; Lisa M Sullivan; Ralph B D'Agostino; Penelope K Elias; Paul F Jacques; Jacob Selhub; Sudha Seshadri; Rhoda Au; Alexa Beiser; Philip A Wolf
Homocysteine and cognitive performance in the Framingham offspring study: age is important.
American journal of epidemiology 2005;162(7):644-53.
2005: Unhee Lim; Kun Peng; Barry Shane; Patrick J Stover; Augusto A Litonjua; Scott Weiss; J Michael Gaziano; Robert L Strawderman; Farbod Raiszadeh; Jacob Selhub; Katherine L Tucker; Patricia A Cassano
Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.
The Journal of nutrition 2005;135(8):1989-94.
2005: Allon N Friedman; Lawrence G Hunsicker; Jacob Selhub; Andrew G Bostom
C-reactive protein as a predictor of total arteriosclerotic outcomes in type 2 diabetic nephropathy.
Kidney international 2005;68(2):773-8.
2005: Martha Savaria Morris; Paul F Jacques; Jacob Selhub
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans.
Bone 2005;37(2):234-42.
2005: Vincent T Ramaekers; Sheldon P Rothenberg; Jeffrey M Sequeira; Thomas Opladen; Nenad Blau; Edward V Quadros; Jacob Selhub
Autoantibodies to folate receptors in the cerebral folate deficiency syndrome.
The New England journal of medicine 2005;352(19):1985-91.
2005: Esther K Wei; Edward Giovannucci; Jacob Selhub; Charlie S Fuchs; Susan E Hankinson; Jing Ma
Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women.
Journal of the National Cancer Institute 2005;97(9):684-92.
2005: Steven R Davis; Eoin P Quinlivan; Karla P Shelnutt; Haifa Ghandour; Antonieta Capdevila; Bonnie S Coats; Conrad Wagner; Barry Shane; Jacob Selhub; Lynn B Bailey; Jonathan J Shuster; Peter W Stacpoole; Jesse F Gregory
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
The Journal of nutrition 2005;135(5):1045-50.
2005: Steven R Davis; Eoin P Quinlivan; Karla P Shelnutt; David R Maneval; Haifa Ghandour; Antonieta Capdevila; Bonnie S Coats; Conrad Wagner; Jacob Selhub; Lynn B Bailey; Jonathan J Shuster; Peter W Stacpoole; Jesse F Gregory
The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women.
The Journal of nutrition 2005;135(5):1040-4.
2005: Vandana Menon; Xuelei Wang; Tom Greene; Gerald J Beck; John W Kusek; Jacob Selhub; Andrew S Levey; Mark J Sarnak
Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins.
Kidney international 2005;67(4):1539-46.
2005: Eoin P Quinlivan; Steven R Davis; Karla P Shelnutt; George N Henderson; Haifa Ghandour; Barry Shane; Jacob Selhub; Lynn B Bailey; Peter W Stacpoole; Jesse F Gregory
Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides.
The Journal of nutrition 2005;135(3):389-96.
2005: Ofer Spiegelstein; Amy Gould; Bogdan Wlodarczyk; Marlene Tsie; Xiufen Lu; Chris Le; Aron Troen; Jacob Selhub; Jorge A Piedrahita; J Michael Salbaum; Claudia Kappen; Stepan Melnyk; Jill James; Richard Finnell
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.
Toxicology and applied pharmacology 2005;203(1):18-26.
2005: Deborah M Kado; Arun S Karlamangla; Mei-Hua Huang; Aron Troen; John W Rowe; Jacob Selhub; Teresa Seeman
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
The American journal of medicine 2005;118(2):161-7.
2005: Ofer Spiegelstein; Aron Troen; S Jill James; X Chris Le; Xiufen Lu; Stepan Melnyk; Jacob Selhub; Richard H Finnell
Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice.
Environmental toxicology and pharmacology 2005;19(1):1-7.
2005: En-Pei Chiang; Jacob Selhub; Pamela J Bagley; Gerard Dallal; Ronenn Roubenoff
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis.
Arthritis research & therapy 2005;7(6):R1404-11.
2005: En-Pei Chiang; Donald E Smith; Jacob Selhub; Gerard Dallal; Yi-Cheng Wang; Ronenn Roubenoff
Inflammation causes tissue-specific depletion of vitamin B6.
Arthritis research & therapy 2005;7(6):R1254-62.
2005: Katherine L Tucker; Marian T Hannan; Ning Qiao; Paul F Jacques; Jacob Selhub; L Adrienne Cupples; Douglas P Kiel
Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(1):152-8.
2004: Iris Shai; Meir J Stampfer; Jing Ma; JoAnn E Manson; Susan E Hankinson; Carolyn C Cannuscio; Jacob Selhub; Gary Curhan; Eric B Rimm
Homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors.
Atherosclerosis 2004;177(2):375-81.
2004: Haifa Ghandour; Zhoutao Chen; Jacob Selhub; Rima Rozen
Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates.
The Journal of nutrition 2004;134(11):2975-8.
2004: Jia Chen; Charles Kyte; Martin Valcin; Wendy Chan; James G Wetmur; Jacob Selhub; David J Hunter; Jing Ma
Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study.
International journal of cancer. Journal international du cancer 2004;110(4):617-20.
2004: Robert R McLean; Paul F Jacques; Jacob Selhub; Katherine L Tucker; Elizabeth J Samelson; Kerry E Broe; Marian T Hannan; L Adrienne Cupples; Douglas P Kiel
Homocysteine as a predictive factor for hip fracture in older persons.
The New England journal of medicine 2004;350(20):2042-9.
2004: Katherine L Tucker; Beth Olson; Peter Bakun; Gerard Dallal; Jacob Selhub; Irwin H Rosenberg
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
The American journal of clinical nutrition 2004;79(5):805-11.
2004: Tahzeeba Hossain; Irwin Rosenberg; Jacob Selhub; Ganesh Kishore; Roger N Beachy; Karel Schubert
Enhancement of folates in plants through metabolic engineering.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):5158-63.
2004: Sang-Woon Choi; Simonetta Friso; Haifa Ghandour; Pamela J Bagley; Jacob Selhub; Joel B Mason
Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium.
The Journal of nutrition 2004;134(4):750-5.
2004: Robert R McLean; David Karasik; Jacob Selhub; Katherine L Tucker; Jose Ordovas; Giuseppina T Russo; L Adrienne Cupples; Paul F Jacques; Douglas P Kiel
Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(3):410-8.
2004: Johan Sundström; Lisa Sullivan; Jacob Selhub; Emelia Benjamin; Ralph B D'Agostino; Paul F Jacques; Irwin H Rosenberg; Daniel Levy; Peter W F Wilson; Ramachandran S Vasan
Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study.
European heart journal 2004;25(6):523-30.
2004: Allon N Friedman; Lawrence G Hunsicker; Jacob Selhub; Andrew G Bostom
Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy.
Atherosclerosis 2004;172(1):121-5.
2003: Aron Troen; Esther Lutgens; Donald E Smith; Irwin H Rosenberg; Jacob Selhub
The atherogenic effect of excess methionine intake.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15089-94.
2003: Johan Sundström; Lisa Sullivan; Ralph B D'Agostino; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg; Peter W F Wilson; Daniel Levy; Ramachandran S Vasan
Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study.
Hypertension 2003;42(6):1100-5.
2003: Ofer Spiegelstein; Xiufen Lu; X Chris Le; Aron Troen; Jacob Selhub; Stepan Melnyk; S Jill James; Richard Finnell
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.
Toxicology letters 2003;145(2):167-74.
2003: Shumin M Zhang; Walter C Willett; Jacob Selhub; JoAnn E Manson; GRaham Colditz; Susan E Hankinson
A prospective study of plasma total cysteine and risk of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(11 Pt 1):1188-93.
2003: Giuseppina T Russo; Simonetta Friso; Paul F Jacques; Gail Rogers; Domenico Cucinotta; Peter W F Wilson; Jose Ordovas; Irwin H Rosenberg; Jacob Selhub
Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort.
The Journal of nutrition 2003;133(11):3416-21.
2003: Jia Chen; David J Hunter; Meir J Stampfer; Charles Kyte; Wendy Chan; James G Wetmur; Rebecca Mosig; Jacob Selhub; Jing Ma
Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(10):958-62.
2003: Lori Lathrop Stern; Barry Shane; Pamela J Bagley; Marie Nadeau; Vivian Shih; Jacob Selhub
Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.
The Journal of nutrition 2003;133(9):2716-20.
2003: Montserrat C Anguera; Jae Rin Suh; Haifa Ghandour; Ilya M Nasrallah; Jacob Selhub; Patrick J Stover
Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation.
The Journal of biological chemistry 2003;278(32):29856-62.
2003: Aviva Must; Paul F Jacques; Gail Rogers; Irwin H Rosenberg; Jacob Selhub
Serum total homocysteine concentrations in children and adolescents: results from the third National Health and Nutrition Examination Survey (NHANES III).
The Journal of nutrition 2003;133(8):2643-9.
2003: Mi Kyung Kim; Jose Ordovas; Jacob Selhub; HANNIA CAMPOS
B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica.
Journal of the American College of Nutrition 2003;22(3):224-31.
2003: En-Pei Chiang; Pamela J Bagley; Ronenn Roubenoff; Marie Nadeau; Jacob Selhub
Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status.
The Journal of nutrition 2003;133(4):1056-9.
2003: Ramachandran S Vasan; Alexa Beiser; Ralph B D'Agostino; Daniel Levy; Jacob Selhub; Paul F Jacques; Irwin H Rosenberg; Peter W F Wilson
Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction.
JAMA : the journal of the American Medical Association 2003;289(10):1251-7.
2003: Shumin M Zhang; Walter C Willett; Jacob Selhub; David J Hunter; Edward L Giovannucci; Michelle D Holmes; GRaham Colditz; Susan E Hankinson
Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.
Journal of the National Cancer Institute 2003;95(5):373-80.
2003: En-Pei Chiang; Pamela J Bagley; Jacob Selhub; Marie Nadeau; Ronenn Roubenoff
Abnormal vitamin B(6) status is associated with severity of symptoms in patients with rheumatoid arthritis.
The American journal of medicine 2003;114(4):283-7.
2003: Martha Savaria Morris; Maurizio Fava; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Depression and folate status in the US Population.
Psychotherapy and psychosomatics 2003;72(2):80-7.
2003: Allon N Friedman; Andrew G Bostom; Priscilla Laliberty; Jacob Selhub; Douglas Shemin
The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: a randomized, controlled study.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2003;41(2):442-6.
2003: Paul F Jacques; Andrew G Bostom; Jacob Selhub; Sharron Rich; R Curtis Ellison; John H Eckfeldt; Roy A Gravel; Rima Rozen
Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.
Atherosclerosis 2003;166(1):49-55.
2002: Alayne G Ronnenberg; Marlene B Goldman; Dafang Chen; Iain W Aitken; Walter C Willett; Jacob Selhub; Xiping Xu
Preconception homocysteine and B vitamin status and birth outcomes in Chinese women.
The American journal of clinical nutrition 2002;76(6):1385-91.
2002: Haifa Ghandour; Pamela J Bagley; Douglas Shemin; Natalie Hsu; Paul F Jacques; Lance D Dworkin; Andrew G Bostom; Jacob Selhub
Distribution of plasma folate forms in hemodialysis patients receiving high daily doses of L-folinic or folic acid.
Kidney international 2002;62(6):2246-9.
2002: Deborah M Kado; Alexander Bucur; Jacob Selhub; John W Rowe; Teresa Seeman
Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging.
The American journal of medicine 2002;113(7):537-42.
2002: Geoffrey H Tofler; Ralph B D'Agostino; Paul F Jacques; Andrew G Bostom; Peter W F Wilson; Izabella Lipinska; Murray A Mittleman; Jacob Selhub
Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk.
Thrombosis and haemostasis 2002;88(5):799-804.
2002: Mark J Sarnak; Shin-Ru Wang; Gerald J Beck; John W Kusek; Jacob Selhub; Tom Greene; Andrew S Levey
Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;40(5):932-9.
2002: Allon N Friedman; Lawrence G Hunsicker; Jacob Selhub; Andrew G Bostom
Proteinuria as a predictor of total plasma homocysteine levels in type 2 diabetic nephropathy.
Diabetes care 2002;25(11):2037-41.
2002: Simonetta Friso; Sang-Woon Choi; Gregory G Dolnikowski; Jacob Selhub
A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry.
Analytical chemistry 2002;74(17):4526-31.
2002: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Elevated serum methylmalonic acid concentrations are common among elderly Americans.
The Journal of nutrition 2002;132(9):2799-803.
2002: Silvina F Choumenkovitch; Jacob Selhub; Peter W F Wilson; Jeanne I Rader; Irwin H Rosenberg; Paul F Jacques
Folic acid intake from fortification in United States exceeds predictions.
The Journal of nutrition 2002;132(9):2792-8.
2002: Pamela Tran; Francois Hiou-Tim; Phyllis Frosst; Suzanne Lussier-Cacan; Pamela Bagley; Jacob Selhub; Teodoro Bottiglieri; Rima Rozen
The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr.
Molecular genetics and metabolism 2002;76(4):297-304.
2002: Silvina F Choumenkovitch; Jacob Selhub; Pamela J Bagley; Nobuyo Maeda; Marie Nadeau; Donald E Smith; Sang-Woon Choi
In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific.
The Journal of nutrition 2002;132(8):2157-60.
2002: Alayne G Ronnenberg; Marlene B Goldman; Dafang Chen; Iain W Aitken; Walter C Willett; Jacob Selhub; Xiping Xu
Preconception folate and vitamin B(6) status and clinical spontaneous abortion in Chinese women.
Obstetrics and gynecology 2002;100(1):107-13.
2002: Jia Chen; Jing Ma; Meir J Stampfer; Caroline Palomeque; Jacob Selhub; David J Hunter
Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer.
Pharmacogenetics 2002;12(4):339-42.
2002: Haifa Ghandour; Bi-Fong Lin; Sang-Woon Choi; Joel B Mason; Jacob Selhub
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
The Journal of nutrition 2002;132(6):1357-60.
2002: Carolina Vargas-Martinez; Jose Ordovas; Peter W Wilson; Jacob Selhub
The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort.
The Journal of nutrition 2002;132(6):1176-9.
2002: Jennifer M Burgoon; Jacob Selhub; Marie Nadeau; Thomas W Sadler
Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model.
Teratology 2002;65(5):219-27.
2002: Simonetta Friso; Sang-Woon Choi; Domenico Girelli; Joel B Mason; Gregory G Dolnikowski; Pamela J Bagley; Oliviero Olivieri; Paul F Jacques; Irwin H Rosenberg; Roberto Corrocher; Jacob Selhub
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5606-11.
2002: Allon N Friedman; Irwin H Rosenberg; Jacob Selhub; Andrew S Levey; Andrew G Bostom
Hyperhomocysteinemia in renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(4):308-13.
2002: Andrew G Bostom; Paul F Jacques; Gintaras Liaugaudas; Gail Rogers; Irwin H Rosenberg; Jacob Selhub
Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):488-91.
2002: Sudha Seshadri; Alexa Beiser; Jacob Selhub; Paul F Jacques; Irwin H Rosenberg; Ralph B D'Agostino; Peter W F Wilson; Philip A Wolf
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.
The New England journal of medicine 2002;346(7):476-83.
2002: Paul F Jacques; Renee Kalmbach; Pamela J Bagley; Giuseppina T Russo; Gail Rogers; Peter W F Wilson; Irwin H Rosenberg; Jacob Selhub
The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.
The Journal of nutrition 2002;132(2):283-8.
2002: Allon N Friedman; Andrew G Bostom; Andrew S Levey; Irwin H Rosenberg; Jacob Selhub; Andreas Pierratos
Plasma total homocysteine levels among patients undergoing nocturnal versus standard hemodialysis.
Journal of the American Society of Nephrology : JASN 2002;13(1):265-8.
2001: Manning Feinleib; S A Beresford; B A Bowman; J L Mills; Jeanne I Rader; Jacob Selhub; Elizabeth A Yetley
Folate fortification for the prevention of birth defects: case study.
American journal of epidemiology 2001;154(12 Suppl):S60-9.
2001: Jia Chen; Jing Ma; Meir J Stampfer; L M Hines; Jacob Selhub; David J Hunter
Alcohol dehydrogenase 3 genotype is not predictive for risk of colorectal cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(12):1303-4.
2001: Silvina F Choumenkovitch; Paul F Jacques; Marie Nadeau; Peter W F Wilson; Irwin H Rosenberg; Jacob Selhub
Folic acid fortification increases red blood cell folate concentrations in the Framingham study.
The Journal of nutrition 2001;131(12):3277-80.
2001: Andrew G Bostom; Florian Kronenberg; Paul F Jacques; Erich Kuen; E Ritz; Paul König; Günter Kraatz; Karl Lhotta; J F Mann; G A Müller; Ulrich Neyer; Werner Riegel; V Schwenger; Peter Riegler; Jacob Selhub
Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate.
Atherosclerosis 2001;159(1):219-23.
2001: Douglas Shemin; Andrew G Bostom; Jacob Selhub
Treatment of hyperhomocysteinemia in end-stage renal disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;38(4 Suppl 1):S91-4.
2001: Allon N Friedman; Andrew G Bostom; Jacob Selhub; Andrew S Levey; Irwin H Rosenberg
The kidney and homocysteine metabolism.
Journal of the American Society of Nephrology : JASN 2001;12(10):2181-9.
2001: Andrew G Bostom; Jacob Selhub; Paul F Jacques; Irwin H Rosenberg
Power Shortage: clinical trials testing the "homocysteine hypothesis" against a background of folic acid-fortified cereal grain flour.
Annals of internal medicine 2001;135(2):133-7.
2001: S Friso; Paul F Jacques; Peter W F Wilson; Irwin H Rosenberg; Jacob Selhub
Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels.
Circulation 2001;103(23):2788-91.
2001: Ilan S Weisberg; P F Jacques; Jacob Selhub; A G Bostom; Zhoutao Chen; R Curtis Ellison; J H Eckfeldt; Rima Rozen
The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine.
Atherosclerosis 2001;156(2):409-15.
2001: Andrew G Bostom; Florian Kronenberg; Reginald Y Gohh; V Schwenger; Erich Kuen; Paul König; Günter Kraatz; Karl Lhotta; J F Mann; G A Müller; Ulrich Neyer; Werner Riegel; Peter Riegler; E Ritz; Jacob Selhub
Chronic renal transplantation: a model for the hyperhomocysteinemia of renal insufficiency.
Atherosclerosis 2001;156(1):227-30.
2001: Gintaras Liaugaudas; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg; Andrew G Bostom
Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):849-51.
2001: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey.
The American journal of clinical nutrition 2001;73(5):927-33.
2001: Martha Savaria Morris; A G Bostom; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey.
Atherosclerosis 2001;155(1):195-200.
2001: Zhoutao Chen; Andrew C Karaplis; S L Ackerman; Igor P Pogribny; Stepan Melnyk; Suzanne Lussier-Cacan; Moy Fong Chen; Aditya Pai; S W John; R S Smith; Teodoro Bottiglieri; P Bagley; Jacob Selhub; M A Rudnicki; S Jill James; Rima Rozen
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.
Human molecular genetics 2001;10(5):433-43.
2001: Jia Chen; Meir J Stampfer; Jing Ma; Jacob Selhub; M R Malinow; Charles H Hennekens; David J Hunter
Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction.
Atherosclerosis 2001;154(3):667-72.
2001: Andrew G Bostom; Douglas Shemin; Reginald Y Gohh; AJ Beaulieu; Pamela J Bagley; Z A Massy; Paul F Jacques; Lance D Dworkin; Jacob Selhub
Treatment of hyperhomocysteinemia in hemodialysis patients and renal transplant recipients.
Kidney international. Supplement 2001;78():S246-52.
2001: Angelito Yango; Douglas Shemin; N Hsu; Paul F Jacques; Lance D Dworkin; Jacob Selhub; Andrew G Bostom
Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Kidney international 2001;59(1):324-7.
2000: Martha Savaria Morris; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub; Barbara A Bowman; Elaine W Gunter; J D Wright; C L Johnson
Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III.
The Journal of nutrition 2000;130(12):3073-6.
2000: L L Stern; Pamela J Bagley; I H Rosenberg; Jacob Selhub
Conversion of 5-formyltetrahydrofolic acid to 5-methyltetrahydrofolic acid is unimpaired in folate-adequate persons homozygous for the C677T mutation in the methylenetetrahydrofolate reductase gene.
The Journal of nutrition 2000;130(9):2238-42.
2000: L L Stern; J B Mason; Jacob Selhub; Sang-Woon Choi
Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(8):849-53.
2000: Martha Savaria Morris; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey.
American journal of epidemiology 2000;152(2):140-8.
2000: Andrew G Bostom; Douglas Shemin; Pamela J Bagley; Z A Massy; A Zanabli; K Christopher; P Spiegel; Paul F Jacques; Lance D Dworkin; Jacob Selhub
Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Circulation 2000;101(24):2829-32.
2000: Andrew G Bostom; Douglas Shemin; Reginald Y Gohh; AJ Beaulieu; Paul F Jacques; Lance D Dworkin; Jacob Selhub
Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients.
Transplantation 2000;69(10):2128-31.
2000: Felix Stickel; Sang-Woon Choi; Y I Kim; Pamela J Bagley; Helmut K Seitz; R M Russell; Jacob Selhub; Joel B Mason
Effect of chronic alcohol consumption on total plasma homocysteine level in rats.
Alcoholism, clinical and experimental research 2000;24(3):259-64.
2000: Jacob Selhub; L C Bagley; Joshua Miller; Irwin H Rosenberg
B vitamins, homocysteine, and neurocognitive function in the elderly.
The American journal of clinical nutrition 2000;71(2):614S-620S.
2000: Jacob Selhub; Paul F Jacques; Andrew G Bostom; Peter W F Wilson; Irwin H Rosenberg
Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification.
Public health reviews 2000;28(1-4):117-45.
1999: AJ Beaulieu; Reginald Y Gohh; H Han; D Hakas; Paul F Jacques; Jacob Selhub; Andrew G Bostom
Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(12):2918-21.
1999: Andrew G Bostom; Irwin H Rosenberg; H Silbershatz; Paul F Jacques; Jacob Selhub; R B D'Agostino; Peter W F Wilson; Philip A Wolf
Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study.
Annals of internal medicine 1999;131(5):352-5.
1999: Jacob Selhub; Paul F Jacques; Irwin H Rosenberg; Gail Rogers; Barbara A Bowman; Elaine W Gunter; J D Wright; C L Johnson
Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations.
Annals of internal medicine 1999;131(5):331-9.
1999: Andrew G Bostom; L Bausserman; Paul F Jacques; Gintaras Liaugaudas; Jacob Selhub; Irwin H Rosenberg
Cystatin C as a determinant of fasting plasma total homocysteine levels in coronary artery disease patients with normal serum creatinine.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(9):2241-4.
1999: AJ Beaulieu; K L Lapane; Reginald Y Gohh; Jacob Selhub; Anthony P Monaco; Lance D Dworkin; Irwin H Rosenberg; Andrew G Bostom
Short-term reproducibility of total homocysteine determinations in stable renal transplant recipients.
Transplantation proceedings 1999;31(5):2121-3.
1999: Andrew G Bostom; Reginald Y Gohh; AJ Beaulieu; H Han; Paul F Jacques; Jacob Selhub; Lance D Dworkin; Irwin H Rosenberg
Determinants of fasting plasma total homocysteine levels among chronic stable renal transplant recipients.
Transplantation 1999;68(2):257-61.
1999: Andrew G Bostom; Reginald Y Gohh; Gintaras Liaugaudas; AJ Beaulieu; H Han; Paul F Jacques; Lance D Dworkin; Irwin H Rosenberg; Jacob Selhub
Prevalence of mild fasting hyperhomocysteinemia in renal transplant versus coronary artery disease patients after fortification of cereal grain flour with folic acid.
Atherosclerosis 1999;145(1):221-4.
1999: Paul F Jacques; Jacob Selhub; A G Bostom; Peter W F Wilson; Irwin H Rosenberg
The effect of folic acid fortification on plasma folate and total homocysteine concentrations.
The New England journal of medicine 1999;340(19):1449-54.
1999: Paul F Jacques; Irwin H Rosenberg; Gail Rogers; Jacob Selhub; Barbara A Bowman; Elaine W Gunter; J D Wright; C L Johnson
Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey.
The American journal of clinical nutrition 1999;69(3):482-9.
1999: Jacob Selhub
Homocysteine metabolism.
Annual review of nutrition 1999;19():217-46.
1999: Andrew G Bostom; Reginald Y Gohh; L Bausserman; D Hakas; Paul F Jacques; Jacob Selhub; Lance D Dworkin; Irwin H Rosenberg
Serum cystatin C as a determinant of fasting total homocysteine levels in renal transplant recipients with a normal serum creatinine.
Journal of the American Society of Nephrology : JASN 1999;10(1):164-6.
1998: E Seyoum; Jacob Selhub
Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action.
The Journal of nutrition 1998;128(11):1956-60.
1998: P J Bagley; Jacob Selhub
A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13217-20.
1998: Jacob Selhub; A D'Angelo
Relationship between homocysteine and thrombotic disease.
The American journal of the medical sciences 1998;316(2):129-41.
1998: Andrew G Bostom; Douglas Shemin; Reginald Y Gohh; P Verhoef; Marie Nadeau; L A Bianchi; B J Hopkins-Garcia; Paul F Jacques; Jacob Selhub; Lance D Dworkin; Irwin H Rosenberg
Lower fasting total plasma homocysteine levels in stable renal transplant recipients versus maintenance dialysis patients.
Transplantation proceedings 1998;30(1):160-2.
1997: Andrew G Bostom; Reginald Y Gohh; AJ Beaulieu; Marie Nadeau; A L Hume; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Treatment of hyperhomocysteinemia in renal transplant recipients. A randomized, placebo-controlled trial.
Annals of internal medicine 1997;127(12):1089-92.
1997: Andrew G Bostom; Douglas Shemin; P Verhoef; Marie Nadeau; Paul F Jacques; Jacob Selhub; Lance D Dworkin; Irwin H Rosenberg
Elevated fasting total plasma homocysteine levels and cardiovascular disease outcomes in maintenance dialysis patients. A prospective study.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2554-8.
1997: Andrew G Bostom; Reginald Y Gohh; M Y Tsai; B J Hopkins-Garcia; Marie Nadeau; L A Bianchi; Paul F Jacques; Irwin H Rosenberg; Jacob Selhub
Excess prevalence of fasting and postmethionine-loading hyperhomocysteinemia in stable renal transplant recipients.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):1894-900.
1997: Jacob Selhub; A D'Angelo
Hyperhomocysteinemia and thrombosis: acquired conditions.
Thrombosis and haemostasis 1997;78(1):527-31.
1997: Ronenn Roubenoff; P Dellaripa; Marie Nadeau; Leslie W Abad; B A Muldoon; Jacob Selhub; Irwin H Rosenberg
Abnormal homocysteine metabolism in rheumatoid arthritis.
Arthritis and rheumatism 1997;40(4):718-22.
1997: Paul M Ridker; Charles H Hennekens; Jacob Selhub; JP Miletich; M R Malinow; Meir J Stampfer
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism.
Circulation 1997;95(7):1777-82.
1997: Benedicte Christensen; Phyllis Frosst; Suzanne Lussier-Cacan; Jacob Selhub; Philippe Goyette; David S Rosenblatt; Jacques Genest; Rima Rozen
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(3):569-73.
1997: Y I Kim; Igor P Pogribny; AG Basnakian; Joshua Miller; Jacob Selhub; S Jill James; J B Mason
Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene.
The American journal of clinical nutrition 1997;65(1):46-52.
1996: Katherine L Tucker; B Mahnken; Peter W F Wilson; P Jacques; Jacob Selhub
Folic acid fortification of the food supply. Potential benefits and risks for the elderly population.
JAMA : the journal of the American Medical Association 1996;276(23):1879-85.
1996: J Ma; Meir J Stampfer; Charles H Hennekens; Phyllis Frosst; Jacob Selhub; J Horsford; M Rene Malinow; Walter C Willett; Rima Rozen
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians.
Circulation 1996;94(10):2410-6.
1996: Andrew G Bostom; Douglas Shemin; Kate L Lapane; P Sutherland; Marie Nadeau; P W Wilson; D Yoburn; L Bausserman; G Tofler; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Hyperhomocysteinemia, hyperfibrinogenemia, and lipoprotein (a) excess in maintenance dialysis patients: a matched case-control study.
Atherosclerosis 1996;125(1):91-101.
1996: Andrew G Bostom; Douglas Shemin; Kate L Lapane; Marie Nadeau; P Sutherland; J Chan; R Rozen; D Yoburn; Paul F Jacques; Jacob Selhub; Irwin H Rosenberg
Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients.
Atherosclerosis 1996;123(1-2):193-202.
1996: Andrew G Bostom; Douglas Shemin; D Yoburn; D H Fisher; Marie Nadeau; Jacob Selhub
Lack of effect of oral N-acetylcysteine on the acute dialysis-related lowering of total plasma homocysteine in hemodialysis patients.
Atherosclerosis 1996;120(1-2):241-4.
1996: Marília Cravo; LM Glória; Jacob Selhub; M R Nadeau; M E Camilo; M P Resende; J N Cardoso; C Nobre Leitão; FC Mira
Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status.
The American journal of clinical nutrition 1996;63(2):220-4.
1996: Andrew G Bostom; Douglas Shemin; Kate L Lapane; A L Hume; D Yoburn; Marie Nadeau; A Bendich; Jacob Selhub; Irwin H Rosenberg
High dose-B-vitamin treatment of hyperhomocysteinemia in dialysis patients.
Kidney international 1996;49(1):147-52.
1996: Paul F Jacques; Andrew G Bostom; R R Williams; R C Ellison; J H Eckfeldt; Irwin H Rosenberg; Jacob Selhub; R Rozen
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.
Circulation 1996;93(1):7-9.
1995: Andrew G Bostom; Paul F Jacques; Marie Nadeau; R R Williams; R C Ellison; Jacob Selhub
Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: initial results from the NHLBI Family Heart Study.
Atherosclerosis 1995;116(1):147-51.
1995: Young-In Kim; J K Christman; James C Fleet; Marília Cravo; R N Salomon; D Smith; Jose Ordovas; Jacob Selhub; J B Mason
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
The American journal of clinical nutrition 1995;61(5):1083-90.
1995: Andrew G Bostom; Douglas Shemin; Marie Nadeau; V Shih; S P Stabler; R H Allen; Jacob Selhub
Short term betaine therapy fails to lower elevated fasting total plasma homocysteine concentrations in hemodialysis patients maintained on chronic folic acid supplementation.
Atherosclerosis 1995;113(1):129-32.
1995: R Roubenoff; Ronenn Roubenoff; Jacob Selhub; Marie Nadeau; Joseph Cannon; L M Freeman; C A Dinarello; Irwin H Rosenberg
Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation.
Arthritis and rheumatism 1995;38(1):105-9.
1994: Andrew G Bostom; Lisa R Yanek; A L Hume; C B Eaton; W McQuade; Marie Nadeau; G Perrone; Paul F Jacques; Jacob Selhub
High dose ascorbate supplementation fails to affect plasma homocyst(e)ine levels in patients with coronary heart disease.
Atherosclerosis 1994;111(2):267-70.
1994: Young-In Kim; Joshua Miller; Kerry-Ann da Costa; M Nadeau; D Smith; Jacob Selhub; Steven H Zeisel; J B Mason
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver.
The Journal of nutrition 1994;124(11):2197-203.
1994: Marília Cravo; P Fidalgo; A Dias Pereira; Antonio Oliveira; Paula Chaves; Jacob Selhub; J B Mason; FC Mira; C N Leitao
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1994;3(6):473-9.
1994: N Hidiroglou; M E Camilo; Harriet C Beckenhauer; Dean J Tuma; Anthony J Barak; P F Nixon; Jacob Selhub
Effect of chronic alcohol ingestion on hepatic folate distribution in the rat.
Biochemical pharmacology 1994;47(9):1561-6.
1994: Joshua Miller; M R Nadeau; J Smith; D Smith; Jacob Selhub
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
The Biochemical journal 1994;298 ( Pt 2)():415-9.
1993: Anthony J Barak; Harriet C Beckenhauer; N Hidiroglou; M E Camilo; Jacob Selhub; Dean J Tuma
The relationship of ethanol feeding to the methyl folate trap.
Alcohol (Fayetteville, N.Y.) 1993;10(6):495-7.
1993: Andrew G Bostom; C B Eaton; Lisa R Yanek; W McQuade; J Catalfamo; Jacob Selhub
Elevations in total plasma homocysteine in premature coronary artery, cerebrovascular and peripheral vascular disease.
Atherosclerosis 1993;102(1):121-4.
1992: Marília Cravo; J B Mason; Y Dayal; M Hutchinson; D Smith; Jacob Selhub; I H Rosenberg
Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats.
Cancer research 1992;52(18):5002-6.
1992: Joshua Miller; Judy D Ribaya-Mercado; Robert M Russell; D C Shepard; F D Morrow; E F Cochary; JA Sadowski; S N Gershoff; Jacob Selhub
Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations.
The American journal of clinical nutrition 1992;55(6):1154-60.
1992: G Varela-Moreiras; Jacob Selhub
Long-term folate deficiency alters folate content and distribution differentially in rat tissues.
The Journal of nutrition 1992;122(4):986-91.
1992: Jacob Selhub; Joshua Miller
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
The American journal of clinical nutrition 1992;55(1):131-8.
1991: Marília Cravo; J B Mason; Jacob Selhub; I H Rosenberg
Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium.
The American journal of clinical nutrition 1991;53(6):1450-54.
1990: J B Mason; R Shoda; M Haskell; Jacob Selhub; I H Rosenberg
Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine.
Biochimica et biophysica acta 1990;1024(2):331-5.
1990: D Fell; Jacob Selhub
Disruption of thymidylate synthesis and glycine-serine interconversion by L-methionine and L-homocystine in Raji cells.
Biochimica et biophysica acta 1990;1033(1):80-4.