FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Galina Selivanova

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Genes, p53

Disorders

Anatomy

Physiology

Phenomena

Protein Binding

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Stephen D Smith; Minna Thullberg; Wenjie Bao; Tânia D F Costa; Martin Enge; Behxhet Gashi; Helene Olofsson; Galina Selivanova; Staffan Strömblad
Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo.
Joanna Zawacka-Pankau; Martin Enge; Angela Gluch; Vera V Grinkevich; Sabine Hünten; Alexander Kel; Hai Li; Fedor Nikulenkov; Galina Selivanova
Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer.
Hai Li; Clemens Spinnler; Laszlo Szekely; Andrea Anichini; Ennio Carbone; Martin Enge; Cinzia Garofalo; Klas Kärre; Tadepally Lakshmikanth; Galina Selivanova
Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Galina Selivanova (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Stephen D Smith; Minna Thullberg; Wenjie Bao; Tânia D F Costa; Martin Enge; Behxhet Gashi; Helene Olofsson; Galina Selivanova; Staffan Strömblad
Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo.
The Journal of biological chemistry 2012;287(35):29336-47.
2011: Joanna Zawacka-Pankau; Martin Enge; Angela Gluch; Vera V Grinkevich; Sabine Hünten; Alexander Kel; Hai Li; Fedor Nikulenkov; Galina Selivanova
Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer.
The Journal of biological chemistry 2011;286(48):41600-15.
2011: Hai Li; Clemens Spinnler; Laszlo Szekely; Andrea Anichini; Ennio Carbone; Martin Enge; Cinzia Garofalo; Klas Kärre; Tadepally Lakshmikanth; Galina Selivanova
Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.
Cell cycle (Georgetown, Tex.) 2011;10(19):3346-58.
2011: Roza Zandi; Galina Selivanova; Camilla Laulund Christensen; Thomas Alexander Gerds; Berthe Marie Willumsen; Hans Skovgaard Poulsen
PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(9):2830-41.
2011: Wenjie Bao; Ming Chen; Xu Zhao; Ravjiv Kumar; Clemens Spinnler; Minna Thullberg; Natalia Issaeva; Galina Selivanova; Staffan Strömblad
PRIMA-1Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo.
Cell cycle (Georgetown, Tex.) 2011;10(2):301-7.
2010: Carolyn Y Zhao; Vera V Grinkevich; Fedor Nikulenkov; Wenjie Bao; Galina Selivanova
Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.
Cell cycle (Georgetown, Tex.) 2010;9(9):1847-55.
2010: Carolyn Ying Zhao; Laszlo Szekely; Wenjie Bao; Galina Selivanova
Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation.
Cancer research 2010;70(8):3372-81.
2010: Galina Selivanova
Therapeutic targeting of p53 by small molecules.
Seminars in cancer biology 2010;20(1):46-56.
2009: Galina Selivanova; Johanna Ivaska
Integrins and mutant p53 on the road to metastasis.
Cell 2009;139(7):1220-2.
2009: Elisabeth Hedström; Sofi Eriksson; Joanna Zawacka-Pankau; Elias Arnér; Galina Selivanova
p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.
Cell cycle (Georgetown, Tex.) 2009;8(21):3576-83.
2009: Vera V Grinkevich; Fedor Nikulenkov; Yao Shi; Martin Enge; Wenjie Bao; Alena Maljukova; Angela Gluch; Alexander Kel; Olle Sangfelt; Galina Selivanova
Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.
Cancer cell 2009;15(5):441-53.
2009: Martin Enge; Wenjie Bao; Elisabeth Hedström; Stephen P Jackson; Abdeladim Moumen; Galina Selivanova
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53.
Cancer cell 2009;15(3):171-83.
2009: Elisabeth Hedström; Natalia Issaeva; Martin Enge; Galina Selivanova
Tumor-specific induction of apoptosis by a p53-reactivating compound.
Experimental cell research 2009;315(3):451-61.
2008: Joanna Zawacka-Pankau; Justyna Krachulec; Ireneusz Grulkowski; Krzysztof Piotr Bielawski; Galina Selivanova
The p53-mediated cytotoxicity of photodynamic therapy of cancer: recent advances.
Toxicology and applied pharmacology 2008;232(3):487-97.
2008: Hareth Nahi; Galina Selivanova; S Lehmann; Lars Möllgård; S Bengtzen; H Concha; A Svensson; Klas G Wiman; Mats Merup; Christer Paul
Mutated and non-mutated TP53 as targets in the treatment of leukaemia.
British journal of haematology 2008;141(4):445-53.
2007: Fatemeh Pak; Amos R Mwakigonja; Parviz Kokhaei; Nahid Hosseinzadeh; Pawan Pyakurel; Ephata Kaaya; Gordana Bogdanovic; Galina Selivanova; Peter Biberfeld
Kaposi's sarcoma herpesvirus load in biopsies of cutaneous and oral Kaposi's sarcoma lesions.
European journal of cancer (Oxford, England : 1990) 2007;43(12):1877-82.
2007: Galina Selivanova; Klas G Wiman
Reactivation of mutant p53: molecular mechanisms and therapeutic potential.
Oncogene 2007;26(15):2243-54.
2007: T Liu; C Laurell; Galina Selivanova; J Lundeberg; Peter Nilsson; Klas G Wiman
Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis.
Cell death and differentiation 2007;14(3):411-21.
2007: Joanna Zawacka-Pankau; Natalia Issaeva; Shakil Hossain; Aladdin Pramanik; Galina Selivanova; Anna J Podhajska
Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner.
The Journal of biological chemistry 2007;282(4):2466-72.
2006: Andrei L Okorokov; Michael B Sherman; Celia Plisson; Vera Grinkevich; Kristmundur Sigmundsson; Galina Selivanova; Jo Milner; Elena V Orlova
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.
The EMBO journal 2006;25(21):5191-200.
2006: Hareth Nahi; Mats Merup; S Lehmann; S Bengtzen; L Möllgård; Galina Selivanova; Klas G Wiman; Christer Paul
PRIMA-1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion.
British journal of haematology 2006;132(2):230-6.
2005: Vladimir Bykov; Natalia Issaeva; Nicole Zache; Alexandre Shilov; Monica Hultcrantz; Jan Bergman; Galina Selivanova; Klas G Wiman
Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.
The Journal of biological chemistry 2005;280(34):30384-91.
2005: Vladimir Bykov; Nicole Zache; Helene Stridh; Jacob Westman; Jan Bergman; Galina Selivanova; Klas G Wiman
PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.
Oncogene 2005;24(21):3484-91.
2005: Igor Y Belyaev; Lena Hillert; Marina Protopopova; Christoffer Tamm; Lars O G Malmgren; Bertil R R Persson; Galina Selivanova; Mats Harms-Ringdahl
915 MHz microwaves and 50 Hz magnetic field affect chromatin conformation and 53BP1 foci in human lymphocytes from hypersensitive and healthy persons.
Bioelectromagnetics 2005;26(3):173-84.
2005: Jesper Torudd; Marina Protopopova; Ruslan Sarimov; Jonas Nygren; Stefan Eriksson; Eva Marková; Miroslav Chovanec; Galina Selivanova; Igor Y Belyaev
Dose-response for radiation-induced apoptosis, residual 53BP1 foci and DNA-loop relaxation in human lymphocytes.
International journal of radiation biology 2005;81(2):125-38.
2005: Fatemeh Pak; Pawan Pyakural; Parviz Kokhaei; Ephata Kaaya; Ali Akbar Pourfathollah; Galina Selivanova; Peter Biberfeld
HHV-8/KSHV during the development of Kaposi's sarcoma: evaluation by polymerase chain reaction and immunohistochemistry.
Journal of cutaneous pathology 2005;32(1):21-7.
2004: Natalia Issaeva; Przemyslaw Bozko; Martin Enge; Marina Protopopova; Lisette G G C Verhoef; Maria Masucci; Aladdin Pramanik; Galina Selivanova
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.
Nature medicine 2004;10(12):1321-8.
2004: Hareth Nahi; S Lehmann; L Mollgard; S Bengtzen; Galina Selivanova; Klas G Wiman; Christer Paul; Mats Merup
Effects of PRIMA-1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion.
British journal of haematology 2004;127(3):285-91.
2004: Galina Selivanova
p53: fighting cancer.
Current cancer drug targets 2004;4(5):385-402.
2004: Galina Selivanova; Alan Fersht
Rescue of the p53 tumor suppressor by a rationally designed molecule.
Discovery medicine 2004;4(20):28-30.
2003: Natalia Issaeva; Assaf Friedler; Przemyslaw Bozko; Klas G Wiman; Alan Fersht; Galina Selivanova
Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13303-7.
2003: Marina Protopopova; Galina Selivanova
Inhibition of p53 activity in vitro and in living cells by a synthetic peptide derived from its core domain.
Cell cycle (Georgetown, Tex.) 2003;2(6):592-5.
2003: Vladimir Bykov; Galina Selivanova; Klas G Wiman
Small molecules that reactivate mutant p53.
European journal of cancer (Oxford, England : 1990) 2003;39(13):1828-34.
2002: Vladimir Bykov; Natalia Issaeva; Galina Selivanova; Klas G Wiman
Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.
Carcinogenesis 2002;23(12):2011-8.
2002: Thomas M Rippin; Vladimir Bykov; Stefan M V Freund; Galina Selivanova; Klas G Wiman; Alan Fersht
Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.
Oncogene 2002;21(14):2119-29.
2002: Jekaterina Erenpreisa; Andrey Ivanov; Mark Cragg; Galina Selivanova; Timothy M Illidge
Nuclear envelope-limited chromatin sheets are part of mitotic death.
Histochemistry and cell biology 2002;117(3):243-55.
2002: Vladimir Bykov; Natalia Issaeva; Alexandre Shilov; Monica Hultcrantz; Elena Pugacheva; Peter Chumakov; Jan Bergman; Klas G Wiman; Galina Selivanova
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.
Nature medicine 2002;8(3):282-8.
2002: Stijn Heessen; Ainars Leonchiks; Natalia Issaeva; Anatoly Sharipo; Galina Selivanova; Maria Masucci; Nico P Dantuma
Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1532-7.
2002: Galina Selivanova
p53 induction as an indicator of DNA damage.
Methods in molecular biology (Clifton, N.J.) 2002;203():279-88.
2001: Jacob Falck; Claudia Lukas; Marina Protopopova; Jiri Lukas; Galina Selivanova; Jiri Bartek
Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.
Oncogene 2001;20(39):5503-10.
2001: Marie Henriksson; Galina Selivanova; M Lindström; Klas G Wiman
Inactivation of Myc-induced p53-dependent apoptosis in human tumors.
Apoptosis : an international journal on programmed cell death 2001;6(1-2):133-7.
2000: Dawei Xu; Q Wang; Astrid Gruber; Magnus Björkholm; Z Chen; A Zaid; Galina Selivanova; C Peterson; Klas G Wiman; P Pisa
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells.
Oncogene 2000;19(45):5123-33.
2000: S B Zotchev; Marina Protopopova; Galina Selivanova
p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core.
Nucleic acids research 2000;28(20):4005-12.
2000: Jekaterina Erenpreisa; Andrey Ivanov; G Dekena; A Vitina; R Krampe; Talivaldis Freivalds; Galina Selivanova; HI Roach
Arrest in metaphase and anatomy of mitotic catastrophe: mild heat shock in two human osteosarcoma cell lines.
Cell biology international 2000;24(2):61-70.
1999: Charlotte Asker; Klas G Wiman; Galina Selivanova
p53-induced apoptosis as a safeguard against cancer.
Biochemical and biophysical research communications 1999;265(1):1-6.
1999: Galina Selivanova; L Ryabchenko; E Jansson; V Iotsova; Klas G Wiman
Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.
Molecular and cellular biology 1999;19(5):3395-402.
1998: Galina Selivanova; T Kawasaki; L Ryabchenko; Klas G Wiman
Reactivation of mutant p53: a new strategy for cancer therapy.
Seminars in cancer biology 1998;8(5):369-78.
1997: Galina Selivanova; V Iotsova; I Okan; Michael Fritsche; M Ström; B Groner; R C Grafström; Klas G Wiman
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain.
Nature medicine 1997;3(6):632-8.
1996: Galina Selivanova; V Iotsova; E Kiseleva; M Ström; Georgy Bakalkin; Roland C Grafström; Klas G Wiman
The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.
Nucleic acids research 1996;24(18):3560-7.
1995: Laszlo Szekely; Katja Pokrovskaja; W Q Jiang; Galina Selivanova; M Löwbeer; NR Ringertz; Klas G Wiman; George Klein
Resting B-cells, EBV-infected B-blasts and established lymphoblastoid cell lines differ in their Rb, p53 and EBNA-5 expression patterns.
Oncogene 1995;10(9):1869-74.
1995: Georgy Bakalkin; Galina Selivanova; Tatiana Yakovleva; E Kiseleva; Elena Kashuba; Kristinn Magnusson; Laszlo Szekely; George Klein; Lars Terenius; Klas G Wiman
p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain.
Nucleic acids research 1995;23(3):362-9.
1995: Galina Selivanova; Klas G Wiman
p53: a cell cycle regulator activated by DNA damage.
Advances in cancer research 1995;66():143-80.
1994: Georgy Bakalkin; Tatiana Yakovleva; Galina Selivanova; Kristinn Magnusson; Laszlo Szekely; E Kiseleva; George Klein; Lars Terenius; Klas G Wiman
p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):413-7.
1993: Laszlo Szekely; Galina Selivanova; Kristinn Magnusson; George Klein; Klas G Wiman
EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5455-9.