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Holger Seltmann

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Anatomy

Chemicals & Drugs

Physiology

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Acne Vulgaris

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Christos Zouboulis; S Angres; Holger Seltmann
Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis.
Evgenia Makrantonaki; Kim Vogel; Sabine Fimmel; Marina Oeff; Holger Seltmann; Christos Zouboulis
Interplay of IGF-I and 17beta-estradiol at age-specific levels in human sebocytes and fibroblasts in vitro.
Edward Pelle; James McCarthy; Holger Seltmann; Xi Huang; Thomas Mammone; Christos Zouboulis; Daniel Maes
Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes.

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All Publications

2011: Christos Zouboulis; S Angres; Holger Seltmann
Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis.
The British journal of dermatology 2011;165(2):269-76.
2008: Evgenia Makrantonaki; Kim Vogel; Sabine Fimmel; Marina Oeff; Holger Seltmann; Christos Zouboulis
Interplay of IGF-I and 17beta-estradiol at age-specific levels in human sebocytes and fibroblasts in vitro.
Experimental gerontology 2008;43(10):939-46.
2008: Edward Pelle; James McCarthy; Holger Seltmann; Xi Huang; Thomas Mammone; Christos Zouboulis; Daniel Maes
Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes.
The Journal of investigative dermatology 2008;128(5):1280-5.
2007: Wesley J Harrison; Jonathan J Bull; Holger Seltmann; Christos Zouboulis; Michael P Philpott
Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytes.
The Journal of investigative dermatology 2007;127(6):1309-17.
2007: Jana Stecová; Wolfgang Mehnert; Tobias Blaschke; Burkhard Kleuser; Ramadurai Sivaramakrishnan; Christos Zouboulis; Holger Seltmann; Hans Christian Korting; Klaus D Kramer; Monika Schäfer-Korting
Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptake.
Pharmaceutical research 2007;24(5):991-1000.
2007: Kristina Seiffert; Holger Seltmann; M Fritsch; Christos Zouboulis
Inhibition of 5alpha-reductase activity in SZ95 sebocytes and HaCaT keratinocytes in vitro.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2007;39(2):141-8.
2006: Qiwei Zhang; Holger Seltmann; Christos Zouboulis; Jeffrey B Travers
Activation of platelet-activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 production.
Experimental dermatology 2006;15(10):769-74.
2006: István Nagy; Andor Pivarcsi; Kornélia Kis; Andrea Koreck; Laszlo Bodai; Andrew McDowell; Holger Seltmann; Sheila Patrick; Christos Zouboulis; Lajos Kemeny
Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes.
Microbes and infection / Institut Pasteur 2006;8(8):2195-205.
2006: Silvia Selleri; Holger Seltmann; Silvia Gariboldi; Yuri F Shirai; Andrea Balsari; Christos Zouboulis; Cristiano Rumio
Doxorubicin-induced alopecia is associated with sebaceous gland degeneration.
The Journal of investigative dermatology 2006;126(4):711-20.
2006: Marina K Oeff; Holger Seltmann; Naoki Hiroi; Aristotelis Nastos; Evgenia Makrantonaki; Stefan R Bornstein; Christos Zouboulis
Differential regulation of Toll-like receptor and CD14 pathways by retinoids and corticosteroids in human sebocytes.
Dermatology (Basel, Switzerland) 2006;213(3):266.
2006: A Winiarska; Nathalie Mandt; Hartwig Kamp; Amir M Hossini; Holger Seltmann; Christos Zouboulis; Ulrike Blume-Peytavi
Effect of 5alpha-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells.
Skin pharmacology and physiology 2006;19(6):311-21.
2006: Qiwei Zhang; Holger Seltmann; Christos Zouboulis; Raymond L Konger
Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells.
The Journal of investigative dermatology 2006;126(1):42-8.
2005: Philippe Georgel; Karine Crozat; Xavier Lauth; Evgenia Makrantonaki; Holger Seltmann; Sosathya Sovath; Kasper Hoebe; Xin Du; Sophie Rutschmann; Zhengfan Jiang; Timothy Bigby; Victor Nizet; Christos Zouboulis; Bruce Beutler
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.
Infection and immunity 2005;73(8):4512-21.
2003: WenChieh Chen; Chao-Chun Yang; Hamm-Ming Sheu; Holger Seltmann; Christos Zouboulis
Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes.
The Journal of investigative dermatology 2003;121(3):441-7.
2003: Henry Fechner; Xiaomin Wang; M Srour; Ulrike Siemetzki; Holger Seltmann; Andreas P Sutter; Hans Scherübl; Christos Zouboulis; Rainer Schwaab; Wolfgang Hillen; Heinz-Peter Schultheiss; Wolfgang Poller
A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication.
Gene therapy 2003;10(19):1680-90.
2003: Anna Wróbel; Holger Seltmann; Sabine Fimmel; Karin Müller-Decker; Miki Tsukada; Birgit Bogdanoff; Nathalie Mandt; Ulrike Blume-Peytavi; Constantin E Orfanos; Christos Zouboulis
Differentiation and apoptosis in human immortalized sebocytes.
The Journal of investigative dermatology 2003;120(2):175-81.
2002: Mariangela Marques; Yong Pei; Michael D Southall; John M Johnston; Hiroyuki Arai; Junken Aoki; Takao Inoue; Holger Seltmann; Christos Zouboulis; Jeffrey B Travers
Identification of platelet-activating factor acetylhydrolase II in human skin.
The Journal of investigative dermatology 2002;119(4):913-9.
2002: Miki Tsukada; Mandy Schröder; Holger Seltmann; Constantin E Orfanos; Christos Zouboulis
High albumin levels restrict the kinetics of 13-cis retinoic acid uptake and intracellular isomerization to all-trans retinoic acid and inhibit its anti-proliferative effect on SZ95 sebocytes.
The Journal of investigative dermatology 2002;119(1):182-5.
2002: Christos Zouboulis; Holger Seltmann; Naoki Hiroi; WenChieh Chen; Maggie Young; Marina K Oeff; Werner A Scherbaum; Constantin E Orfanos; Samuel M McCann; Stefan R Bornstein
Corticotropin-releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7148-53.
2002: Markus Böhm; Meinhard Schiller; Sonja Ständer; Holger Seltmann; Zhuo Li; Thomas Brzoska; Dieter Metze; Helgi B Schiöth; Anna Skottner; Kristina Seiffert; Christos Zouboulis; Thomas A Luger
Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ.
The Journal of investigative dermatology 2002;118(3):533-9.
2000: W C Chen; JO Sass; Holger Seltmann; Heinz Nau; Constantin E Orfanos; Christos Zouboulis
Biological effects and metabolism of 9-cis-retinoic acid and its metabolite 9,13-di-cis-retinoic acid in HaCaT keratinocytes in vitro: comparison with all-trans-retinoic acid.
Archives of dermatological research 2000;292(12):612-20.
1999: Christos Zouboulis; Holger Seltmann; H Neitzel; Constantin E Orfanos
Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95).
The Journal of investigative dermatology 1999;113(6):1011-20.
1999: Christos Zouboulis; Holger Seltmann; JO Sass; Ralph Rühl; Claudia Plum; U Hettmannsperger; Ulrike Blume-Peytavi; Heinz Nau; Constantin E Orfanos
Retinoid signaling by all-trans retinoic acid and all-trans retinoyl-beta-D-glucuronide is attenuated by simultaneous exposure of human keratinocytes to retinol.
The Journal of investigative dermatology 1999;112(2):157-64.
1998: Christos Zouboulis; L Xia; H Akamatsu; Holger Seltmann; M Fritsch; S Hornemann; Ralph Rühl; WenChieh Chen; Heinz Nau; Constantin E Orfanos
The human sebocyte culture model provides new insights into development and management of seborrhoea and acne.
Dermatology (Basel, Switzerland) 1998;196(1):21-31.