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David Blask

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Robert T Dauchy; Lynell M Dupepe; Sheena L Gauthreaux; John P Hanifin; Steven M Hill; Michael R Jablonski; Lulu Mao; Tara G Ooms; Benjamin Warfield; Melissa A Wren; Victoria P Belancio; George C Brainard; Erin M Dauchy; David E Blask
Effects of Spectral Transmittance through Standard Laboratory Cages on Circadian Metabolism and Physiology in Nude Rats.
Lulu Mao; Bin Shan; Lauren M Slakey; Shulin Xiang; Lin Yuan; David E Blask; George C Brainard; Erin M Dauchy; Robert T Dauchy; Tamika T Duplessis; Tripp Frasch; John P Hanifin; Steven M Hill
Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β.
Shulin Xiang; Lin Yuan; Gary W Hoyle; Frank Jones; Lulu Mao; David E Blask; Geetika Chakravarty; Robert T Dauchy; Tamika Duplessis; Tripp Frasch; Steven M Hill
Impaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5.

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All Publications

2013: Robert T Dauchy; Lynell M Dupepe; Sheena L Gauthreaux; John P Hanifin; Steven M Hill; Michael R Jablonski; Lulu Mao; Tara G Ooms; Benjamin Warfield; Melissa A Wren; Victoria P Belancio; George C Brainard; Erin M Dauchy; David E Blask
Effects of Spectral Transmittance through Standard Laboratory Cages on Circadian Metabolism and Physiology in Nude Rats.
Journal of the American Association for Laboratory Animal Science : JAALAS 2013;52(2):146-56.
2012: Lulu Mao; Bin Shan; Lauren M Slakey; Shulin Xiang; Lin Yuan; David E Blask; George C Brainard; Erin M Dauchy; Robert T Dauchy; Tamika T Duplessis; Tripp Frasch; John P Hanifin; Steven M Hill
Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β.
Molecular endocrinology (Baltimore, Md.) 2012;26(11):1808-20.
2012: Shulin Xiang; Lin Yuan; Gary W Hoyle; Frank Jones; Lulu Mao; David E Blask; Geetika Chakravarty; Robert T Dauchy; Tamika Duplessis; Tripp Frasch; Steven M Hill
Impaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5.
Journal of pineal research 2012;53(3):307-18.
2012: Jens Peter Bonde; Harry J de Koning; Johnni Hansen; Mikko Härmä; Helge Kjuus; Henrik A Kolstad; Sigurd Mikkelsen; Morten Møller; Jørn Olsen; Jørgen H Olsen; Eva S Schernhammer; Richard G Stevens; David E Blask; Torbjörn Akerstedt
Work at night and breast cancer--report on evidence-based options for preventive actions.
Scandinavian journal of work, environment & health 2012;38(4):380-90.
2012: Robert T Dauchy; Steven M Hill; Lulu Mao; Victoria P Belancio; Erin M Dauchy; David E Blask
A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats.
Comparative medicine 2012;62(2):99-108.
2011: David E Blask; Erin Dauchy; Robert T Dauchy; Tamika Duplessis; Steven M Hill; Lulu Mao; Shulin Xiang; Lin Yuan; Leonard A Sauer
Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night.
Journal of pineal research 2011;51(3):259-69.
2011: Steven M Hill; Lulu Mao; Shulin Xiang; Lin Yuan; David E Blask; Erin M Dauchy; Robert T Dauchy; Tripp Frasch; Tamika Duplesis
Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer.
Journal of mammary gland biology and neoplasia 2011;16(3):235-45.
2011: Robert T Dauchy; Lynell M Dupepe; Tara G Ooms; Erin M Dauchy; Cody R Hill; Lulu Mao; Victoria P Belancio; Lauren M Slakey; Steven M Hill; David E Blask
Eliminating animal facility light-at-night contamination and its effect on circadian regulation of rodent physiology, tumor growth, and metabolism: a challenge in the relocation of a cancer research laboratory.
Journal of the American Association for Laboratory Animal Science : JAALAS 2011;50(3):326-36.
2011: Steven M Hill; Chi Cheng; Lin Yuan; Lulu Mao; Ralf JOckers; Bob Dauchy; Tripp Frasch; David E Blask
Declining melatonin levels and MT1 receptor expression in aging rats is associated with enhanced mammary tumor growth and decreased sensitivity to melatonin.
Breast cancer research and treatment 2011;127(1):91-8.
2011: Jinghai Wu; Robert T Dauchy; Paul C Tirrell; Steven S Wu; Darin T Lynch; Potjana Jitawatanarat; Christine M Burrington; Erin M Dauchy; David E Blask; Michael Greene
Light at night activates IGF-1R/PDK1 signaling and accelerates tumor growth in human breast cancer xenografts.
Cancer research 2011;71(7):2622-31.
2010: Robert T Dauchy; Erin M Dauchy; Robert P Tirrell; Cody R Hill; Leslie K Davidson; Michael Greene; Paul C Tirrell; Jinghai Wu; Leonard A Sauer; David E Blask
Dark-phase light contamination disrupts circadian rhythms in plasma measures of endocrine physiology and metabolism in rats.
Comparative medicine 2010;60(5):348-56.
2009: David E Blask; Robert T Dauchy; George C Brainard; John P Hanifin
Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women.
Integrative cancer therapies 2009;8(4):347-53.
2009: Robert T Dauchy; David E Blask; Erin M Dauchy; Leslie K Davidson; Paul C Tirrell; Michael Greene; Robert P Tirrell; Cody R Hill; Leonard A Sauer
Antineoplastic effects of melatonin on a rare malignancy of mesenchymal origin: melatonin receptor-mediated inhibition of signal transduction, linoleic acid metabolism and growth in tissue-isolated human leiomyosarcoma xenografts.
Journal of pineal research 2009;47(1):32-42.
2009: David E Blask
Melatonin, sleep disturbance and cancer risk.
Sleep medicine reviews 2009;13(4):257-64.
2007: Leonard A Sauer; David E Blask; Robert T Dauchy
Dietary factors and growth and metabolism in experimental tumors.
The Journal of nutritional biochemistry 2007;18(10):637-49.
2007: Richard G Stevens; David E Blask; George C Brainard; Johnni Hansen; Steven W Lockley; Ignacio Provencio; Mark S Rea; Leslie Reinlib
Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases.
Environmental health perspectives 2007;115(9):1357-62.
2007: Robert T Dauchy; Erin M Dauchy; Leslie K Davidson; Jean A Krause; Darin T Lynch; Paul C Tirrell; Robert P Tirrell; Leonard A Sauer; Peter Van der Riet; David E Blask
Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids.
Comparative medicine 2007;57(4):377-82.
2007: Lawrence Berk; Brian Berkey; tyvin rich; William J M Hrushesky; David E Blask; Michael Gallagher; Mahesh Kudrimoti; Ronald C McGarry; John Suh; Minesh Mehta
Randomized phase II trial of high-dose melatonin and radiation therapy for RPA class 2 patients with brain metastases (RTOG 0119).
International journal of radiation oncology, biology, physics 2007;68(3):852-7.
2006: Erin M Dauchy; Robert T Dauchy; Leslie K Davidson; Darin T Lynch; Jean A Krause; Lia M Blue; Leonard A Sauer; David E Blask
Human cancer xenograft perfusion in situ in rats: a new perfusion system that minimizes delivery time and maintains normal tissue physiology and responsiveness to growth-inhibitory agents.
Journal of the American Association for Laboratory Animal Science : JAALAS 2006;45(3):38-44.
2006: Samar A Jasser; David E Blask; George C Brainard
Light during darkness and cancer: relationships in circadian photoreception and tumor biology.
Cancer causes & control : CCC 2006;17(4):515-23.
2006: Laura C Smith; Erin M Dauchy; Robert T Dauchy; Leonard A Sauer; David E Blask; Leslie K Davidson; Jean A Krause; Darin T Lynch
Dietary fish oil deactivates a growth-promoting signaling pathway in hepatoma 7288CTC in Buffalo rats.
Nutrition and cancer 2006;56(2):204-13.
2005: David E Blask; George C Brainard; Robert T Dauchy; John P Hanifin; Leslie K Davidson; Jean A Krause; Leonard A Sauer; Moises A Rivera-Bermudez; Margarita L Dubocovich; Samar A Jasser; Darin T Lynch; Mark D Rollag; Frederick Zalatan
Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats.
Cancer research 2005;65(23):11174-84.
2005: Leonard A Sauer; Robert T Dauchy; David E Blask; Jean A Krause; Leslie K Davidson; Erin M Dauchy
Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway.
The Journal of nutrition 2005;135(9):2124-9.
2005: David E Blask; Robert T Dauchy; Leonard A Sauer
Putting cancer to sleep at night: the neuroendocrine/circadian melatonin signal.
Endocrine 2005;27(2):179-88.
2004: Leonard A Sauer; Robert T Dauchy; David E Blask; Jean A Krause; Leslie K Davidson; Erin M Dauchy; Kevin J Welham; Keith Coupland
Conjugated linoleic acid isomers and trans fatty acids inhibit fatty acid transport in hepatoma 7288CTC and inguinal fat pads in Buffalo rats.
The Journal of nutrition 2004;134(8):1989-97.
2004: Robert T Dauchy; Erin M Dauchy; Leonard A Sauer; David E Blask; Leslie K Davidson; Jean A Krause; Darin T Lynch
Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid.
Cancer letters 2004;209(1):7-15.
2004: William J M Hrushesky; David E Blask
Re: Melatonin and breast cancer: a prospective study.
Journal of the National Cancer Institute 2004;96(11):888-9.
2004: David E Blask; Robert T Dauchy; Leonard A Sauer; Jean A Krause
Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin.
Carcinogenesis 2004;25(6):951-60.
2003: Frederick D Reynolds; Robert Dauchy; David E Blask; Patrick A Dietz; Darin Lynch; Randall Zuckerman
The pineal gland hormone melatonin improves survival in a rat model of sepsis/shock induced by zymosan A.
Surgery 2003;134(3):474-9.
2003: David E Blask; Robert T Dauchy; Leonard A Sauer; Jean A Krause; George C Brainard
Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression.
Breast cancer research and treatment 2003;79(3):313-20.
2003: Robert T Dauchy; David E Blask; Leonard A Sauer
A new surgical technique for perfusion of the epididymal fat pad in situ in rats.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 2003;42(3):39-43.
2003: Robert T Dauchy; David E Blask; Leonard A Sauer; Leslie K Davidson; Jean A Krause; Laura C Smith; Erin M Dauchy
Physiologic melatonin concentration, omega-3 fatty acids, and conjugated linoleic acid inhibit fatty acid transport in rodent hind limb skeletal muscle in vivo.
Comparative medicine 2003;53(2):186-90.
2002: David E Blask; Robert T Dauchy; Leonard A Sauer; Jean A Krause; George C Brainard
Light during darkness, melatonin suppression and cancer progression.
Neuro endocrinology letters 2002;23 Suppl 2():52-6.
2002: David E Blask; Leonard A Sauer; Robert T Dauchy
Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy.
Current topics in medicinal chemistry 2002;2(2):113-32.
2001: Frederick Zalatan; Jean A Krause; David E Blask
Inhibition of isoproterenol-induced lipolysis in rat inguinal adipocytes in vitro by physiological melatonin via a receptor-mediated mechanism.
Endocrinology 2001;142(9):3783-90.
2001: Leonard A Sauer; Robert T Dauchy; David E Blask
Polyunsaturated fatty acids, melatonin, and cancer prevention.
Biochemical pharmacology 2001;61(12):1455-62.
2001: Leonard A Sauer; Robert T Dauchy; David E Blask
Melatonin inhibits fatty acid transport in inguinal fat pads of hepatoma 7288CTC-bearing and normal Buffalo rats via receptor-mediated signal transduction.
Life sciences 2001;68(25):2835-44.
2000: Leonard A Sauer; Robert T Dauchy; David E Blask
Mechanism for the antitumor and anticachectic effects of n-3 fatty acids.
Cancer research 2000;60(18):5289-95.
2000: Robert T Dauchy; David E Blask; Leonard A Sauer
Preparation of the inguinal fat pad for perfusion in situ in the rat: a surgical technique that preserves continuous blood flow.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 2000;39(5):29-33.
1999: Robert T Dauchy; David E Blask; Leonard A Sauer; George C Brainard; Jean A Krause
Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism.
Cancer letters 1999;144(2):131-6.
1999: David E Blask; Leonard A Sauer; Robert T Dauchy; EW Holowachuk; Mary S Ruhoff; H S Kopff
Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events.
Cancer research 1999;59(18):4693-701.
1999: Leonard A Sauer; Robert T Dauchy; David E Blask; B J Armstrong; S Scalici
13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo.
Cancer research 1999;59(18):4688-92.
1999: David E Blask; Leonard A Sauer; Robert T Dauchy; EW Holowachuk; Mary S Ruhoff
New insights into melatonin regulation of cancer growth.
Advances in experimental medicine and biology 1999;460():337-43.
1999: David E Blask; Leonard A Sauer; Robert T Dauchy; EW Holowachuk; Mary S Ruhoff
New actions of melatonin on tumor metabolism and growth.
Biological signals and receptors 1999;8(1-2):49-55.
1997: Robert T Dauchy; Leonard A Sauer; David E Blask; G M Vaughan
Light contamination during the dark phase in "photoperiodically controlled" animal rooms: effect on tumor growth and metabolism in rats.
Laboratory animal science 1997;47(5):511-8.
1997: Leonard A Sauer; Robert T Dauchy; David E Blask
Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats.
The Journal of nutrition 1997;127(7):1412-21.
1997: David E Blask; S T Wilson; Frederick Zalatan
Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway.
Cancer research 1997;57(10):1909-14.