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Martin Semmelhack

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Publications

TOP 3
Lark J Perez; Bonnie L Bassler; Karolina Brook; Paul Marano; Wai-Leung Ng; Martin F Semmelhack
Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response.
Karthik Sambanthamoorthy; Martin F Semmelhack; Rudolph E Sloup; Joshua M Smith; Eric E Kim; Matthew B Neiditch; Vijay Parashar; Christopher M Waters
Identification of small molecules that antagonize diguanylate cyclase enzymes to inhibit biofilm formation.
Wai-Leung Ng; Lark Perez; Martin F Semmelhack; JP Cong; Bonnie L Bassler
Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.

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All Publications

2012: Lark J Perez; Bonnie L Bassler; Karolina Brook; Paul Marano; Wai-Leung Ng; Martin F Semmelhack
Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response.
Journal of medicinal chemistry 2012;55(22):9669-81.
2012: Karthik Sambanthamoorthy; Martin F Semmelhack; Rudolph E Sloup; Joshua M Smith; Eric E Kim; Matthew B Neiditch; Vijay Parashar; Christopher M Waters
Identification of small molecules that antagonize diguanylate cyclase enzymes to inhibit biofilm formation.
Antimicrobial agents and chemotherapy 2012;56(10):5202-11.
2012: Wai-Leung Ng; Lark Perez; Martin F Semmelhack; JP Cong; Bonnie L Bassler
Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.
PLoS pathogens 2012;8(6):e1002767.
2011: Megan E Bolitho; Matthew J Koch; Wai-Leung Ng; Lark J Perez; Bonnie L Bassler; Martin F Semmelhack
Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit.
Bioorganic & medicinal chemistry 2011;19(22):6906-18.
2011: Karthik Sambanthamoorthy; Martin F Semmelhack; Ankush A Gokhale; Weiwei Lao; Ilsoon Lee; Matthew B Neiditch; Vijay Parashar; Christopher M Waters
Identification of a novel benzimidazole that inhibits bacterial biofilm formation in a broad-spectrum manner.
Antimicrobial agents and chemotherapy 2011;55(9):4369-78.
2011: João C Marques; Pedro Lamosa; Caitlin Russell; Rita Ventura; Christopher Maycock; Martin F Semmelhack; Stephen T Miller; Karina B Xavier
Processing the interspecies quorum-sensing signal autoinducer-2 (AI-2): characterization of phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerization by LsrG protein.
The Journal of biological chemistry 2011;286(20):18331-43.
2011: Yunzhou Wei; Lark J Perez; Wai-Leung Ng; Martin F Semmelhack; Bonnie L Bassler
Mechanism of Vibrio cholerae autoinducer-1 biosynthesis.
ACS chemical biology 2011;6(4):356-65.
2011: Wai-Leung Ng; Lark J Perez; Yunzhou Wei; Christina Kraml; Martin F Semmelhack; Bonnie L Bassler
Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems.
Molecular microbiology 2011;79(6):1407-17.
2011: Charles E Cowles; Yongfeng Li; Martin F Semmelhack; Ileana M Cristea; Thomas J Silhavy
The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli.
Molecular microbiology 2011;79(5):1168-81.
2011: Vitali Stanevich; Li Jiang; Kenneth A Satyshur; Yongfeng Li; Philip Jeffrey; Zhu Li; Patrick Menden; Martin F Semmelhack; Yongna Xing
The structural basis for tight control of PP2A methylation and function by LCMT-1.
Molecular cell 2011;41(3):331-42.
2010: Wai-Leung Ng; Yunzhou Wei; Lark J Perez; JP Cong; Tao Long; Matthew Koch; Martin F Semmelhack; Ned S Wingreen; Bonnie L Bassler
Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(12):5575-80.
2009: Robert C Kelly; Megan E Bolitho; Douglas A Higgins; Wenyun Lu; Wai-Leung Ng; Philip Jeffrey; Joshua D Rabinowitz; Martin F Semmelhack; Frederick M Hughson; Bonnie L Bassler
The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Nature chemical biology 2009;5(12):891-5.
2007: Douglas A Higgins; Megan E Pomianek; Christina M Kraml; Ronald K Taylor; Martin F Semmelhack; Bonnie L Bassler
The major Vibrio cholerae autoinducer and its role in virulence factor production.
Nature 2007;450(7171):883-6.
2007: Bethany A Rader; Shawn R Campagna; Martin F Semmelhack; Bonnie L Bassler; Karen Guillemin
The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori.
Journal of bacteriology 2007;189(17):6109-17.
2007: Megan E Pomianek; Martin F Semmelhack
Making bacteria behave: new agonists and antagonists of quorum sensing.
ACS chemical biology 2007;2(5):293-5.
2007: Karina B Xavier; Stephen T Miller; Wenyun Lu; Jeong Hwan Kim; Joshua Rabinowitz; István Pelczer; Martin F Semmelhack; Bonnie L Bassler
Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria.
ACS chemical biology 2007;2(2):128-36.
2006: Martin F Semmelhack; Richard J Hooley; Christina M Kraml
Synthesis of plakortone B and analogs.
Organic letters 2006;8(23):5203-6.
2006: Alexander Rickard; Robert J Palmer; David S Blehert; Shawn R Campagna; Martin F Semmelhack; Paul G Egland; Bonnie L Bassler; Paul E Kolenbrander
Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.
Molecular microbiology 2006;60(6):1446-56.
2005: Martin F Semmelhack; Anatoly Chlenov; Douglas M Ho
Accelerated arene ligand exchange in the (Arene)Cr(CO)2L series.
Journal of the American Chemical Society 2005;127(21):7759-73.
2005: Martin F Semmelhack; Shawn R Campagna; Michael J Federle; Bonnie L Bassler
An expeditious synthesis of DPD and boron binding studies.
Organic letters 2005;7(4):569-72.
2004: Stephen T Miller; Karina B Xavier; Shawn R Campagna; Michiko E Taga; Martin F Semmelhack; Bonnie L Bassler; Frederick M Hughson
Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2.
Molecular cell 2004;15(5):677-87.
2004: Martin F Semmelhack; Shawn R Campagna; Charlotte Hwa; Michael J Federle; Bonnie L Bassler
Boron binding with the quorum sensing signal AI-2 and analogues.
Organic letters 2004;6(15):2635-7.
2003: Martin F Semmelhack; Lingyun Wu; Robert A Pascal; Douglas M Ho
Conformational control in activation of an enediyne.
Journal of the American Chemical Society 2003;125(35):10496-7.
2002: Rachael A Kipp; Martin A Case; Aislyn D Wist; Catherine M Cresson; Maria Carrell; Erin Griner; Arun Wiita; Philip A Albiniak; Jijie Chai; Yigong Shi; Martin F Semmelhack; George L McLendon
Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners.
Biochemistry 2002;41(23):7344-9.
2001: Martin F Semmelhack; A Chlenov; L Wu; D Ho
Accelerated arene ligand exchange in areneCr(CO(3)) complexes.
Journal of the American Chemical Society 2001;123(34):8438-9.
2001: Martin F Semmelhack; Yu Jiang; D Ho
Synthesis of the amino sugar from C-1027.
Organic letters 2001;3(15):2403-6.