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Michael Sendtner

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TOP 3
Matthias Fischer; Patricia Marques Pereira; Bettina Holtmann; Christian M Simon; Andre Hanauer; Martin Heisenberg; Michael Sendtner
P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons.
Thorsten Trimbuch; Prateep Beed; Johannes Vogt; Sebastian Schuchmann; Nikolaus Maier; Michael Kintscher; Jörg Breustedt; Markus Schuelke; Nora Streu; Olga Kieselmann; Irene Brunk; Gregor Laube; Ulf Strauss; Arne Battefeld; Hagen Wende; Carmen Birchmeier; Stefan Wiese; Michael Sendtner; Hiroshi Kawabe; Mika Kishimoto-Suga; Nils Brose; Jan Baumgart; Beate Geist; Junken Aoki; Nicolai E Savaskan; Anja U Bräuer; Jerold Chun; Olaf Ninnemann; Dietmar Schmitz; Robert Nitsch
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.
Matthias Fischer; Thomas Raabe; Martin Heisenberg; Michael Sendtner
Drosophila RSK negatively regulates bouton number at the neuromuscular junction.

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All Publications

2009: Matthias Fischer; Patricia Marques Pereira; Bettina Holtmann; Christian M Simon; Andre Hanauer; Martin Heisenberg; Michael Sendtner
P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons.
Molecular and cellular neurosciences 2009;42(2):134-41.
2009: Thorsten Trimbuch; Prateep Beed; Johannes Vogt; Sebastian Schuchmann; Nikolaus Maier; Michael Kintscher; Jörg Breustedt; Markus Schuelke; Nora Streu; Olga Kieselmann; Irene Brunk; Gregor Laube; Ulf Strauss; Arne Battefeld; Hagen Wende; Carmen Birchmeier; Stefan Wiese; Michael Sendtner; Hiroshi Kawabe; Mika Kishimoto-Suga; Nils Brose; Jan Baumgart; Beate Geist; Junken Aoki; Nicolai E Savaskan; Anja U Bräuer; Jerold Chun; Olaf Ninnemann; Dietmar Schmitz; Robert Nitsch
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.
Cell 2009;138(6):1222-35.
2009: Matthias Fischer; Thomas Raabe; Martin Heisenberg; Michael Sendtner
Drosophila RSK negatively regulates bouton number at the neuromuscular junction.
Developmental neurobiology 2009;69(4):212-20.
2009: Michael Sendtner
Stem cells: Tailor-made diseased neurons.
Nature 2009;457(7227):269-70.
2008: Koen Poesen; Diether Lambrechts; Philip Van Damme; Joke Dhondt; Florian Bender; Nicolas Frank; Elke Bogaert; Bart Claes; Line Heylen; An Verheyen; Katrien Raes; Marc Tjwa; Ulf Eriksson; Masabumi Shibuya; Rony Nuydens; Ludo Van Den Bosch; Theo F Meert; Rudi D'Hooge; Michael Sendtner; Wim Robberecht; Peter Carmeliet
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(42):10451-9.
2008: Eva M Lang; Nicholas Schlegel; Karlheinz Reiners; Gunther O Hofmann; Michael Sendtner; Esther Asan
Single-dose application of CNTF and BDNF improves remyelination of regenerating nerve fibers after C7 ventral root avulsion and replantation.
Journal of neurotrauma 2008;25(4):384-400.
2008: Ralf A Linker; Niels Kruse; Stephanie Israel; Tao Wei; S Seubert; Anja Hombach; Bettina Holtmann; Fred Luhder; Richard M Ransohoff; Michael Sendtner; Ralf Gold
Leukemia inhibitory factor deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2204-13.
2008: Dominik Brors; Stefan Hansen; Robert Mlynski; Stefan Volkenstein; Christoph Aletsee; Michael Sendtner; Allen F Ryan; Stefan Dazert
Spiral ganglion outgrowth and hearing development in p75-deficient mice.
Audiology & neuro-otology 2008;13(6):388-95.
2007: Alexandra Matzke; Vardanush Sargsyan; Bettina Holtmann; Gayane Aramuni; Esther Asan; Michael Sendtner; Giuseppina Pace; Norma Howells; Weiqi Zhang; Helmut Ponta; Véronique Orian-Rousseau
Haploinsufficiency of c-Met in cd44-/- mice identifies a collaboration of CD44 and c-Met in vivo.
Molecular and cellular biology 2007;27(24):8797-806.
2007: Stefan Wiese; Sibylle Jablonka; Bettina Holtmann; Nadiya Orel; Rithwick Rajagopal; Moses V Chao; Michael Sendtner
Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17210-5.
2007: Sibylle Jablonka; Marcus Beck; Barbara Dorothea Lechner; Christine Mayer; Michael Sendtner
Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy.
The Journal of cell biology 2007;179(1):139-49.
2007: Silke Schreiner; François Cossais; Kerstin Fischer; Stefanie Scholz; Michael R Bösl; Bettina Holtmann; Michael Sendtner; Michael Wegner
Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages.
Development (Cambridge, England) 2007;134(18):3271-81.
2007: Dalia Kasperaviciute; Mike E Weale; Kevin V Shianna; Gareth T Banks; Claire L Simpson; Valerie K Hansen; Martin R Turner; Christopher Shaw; Ammar Al-Chalabi; Hardev S Pall; Emily F Goodall; Karen E Morrison; Richard W Orrell; Marcus Beck; Sibylle Jablonka; Michael Sendtner; Alice Brockington; Paul Geoffrey Ince; Judith Hartley; Hannah Nixon; Pamela J Shaw; Giampietro Schiavo; Nicholas W Wood; David B Goldstein; Elizabeth M C Fisher
Large-scale pathways-based association study in amyotrophic lateral sclerosis.
Brain : a journal of neurology 2007;130(Pt 9):2292-301.
2007: Tania Aguado; Eva Romero; Krisztina Monory; Javier Palazuelos; Michael Sendtner; Giovanni Marsicano; Beat Lutz; Manuel Guzmán; Ismael Galve-Roperh
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.
The Journal of biological chemistry 2007;282(33):23892-8.
2007: Marcus Beck; Michael Sendtner; Klaus V Toyka
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
Muscle & nerve 2007;36(1):111-4.
2007: Florian L P Bender; Matthias Fischer; Natalja Funk; Nadiya Orel; Axel Rethwilm; Michael Sendtner
High-efficiency gene transfer into cultured embryonic motoneurons using recombinant lentiviruses.
Histochemistry and cell biology 2007;127(4):439-48.
2007: Alexandra A Blak; Thorsten Naserke; Jonna Saarimäki-Vire; Paula Peltopuro; Mario Giraldo-Velasquez; Daniela Vogt Weisenhorn; Nilima Prakash; Michael Sendtner; Juha Partanen; Wolfgang Wurst
Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain.
Developmental biology 2007;303(1):231-43.
2007: Karin Frebel; Stefan Wiese; Natalja Funk; Dirk Pühringer; Michael Sendtner
Differential modulation of neurite growth by the S- and the L-forms of bag1, a co-chaperone of Hsp70.
Neuro-degenerative diseases 2007;4(2-3):261-9.
2006: Yasuhiro Ito; Stefan Wiese; Natalja Funk; Alexandra Chittka; wilfried rossoll; Heike Bömmel; Kazuhiko Watabe; Michael Wegner; Michael Sendtner
Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7871-6.
2006: Guillaume Chevrel; Reinhard Hohlfeld; Michael Sendtner
The role of neurotrophins in muscle under physiological and pathological conditions.
Muscle & nerve 2006;33(4):462-76.
2006: Stephan Oberle; Andreas Schober; Verena Meyer; Bettina Holtmann; Christopher Henderson; Michael Sendtner; Klaus Unsicker
Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(6):1823-32.
2006: Sibylle Jablonka; Kathrin Karle; Beatice Sandner; Catia Andreassi; Katja von Au; Michael Sendtner
Distinct and overlapping alterations in motor and sensory neurons in a mouse model of spinal muscular atrophy.
Human molecular genetics 2006;15(3):511-8.
2006: Michael Sendtner
Damaging secretions: chromogranins team up with mutant SOD1.
Nature neuroscience 2006;9(1):12-4.
2005: Fanie Barnabé-Heider; Julie A Wasylnka; Karl J L Fernandes; Christian Porsche; Michael Sendtner; David R Kaplan; Freda D Miller
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.
Neuron 2005;48(2):253-65.
2005: Rudolf Götz; Stefan Wiese; Shinichi Takayama; Guadalupe Camarero; wilfried rossoll; Ulrich Schweizer; Jakob Troppmair; Sibylle Jablonka; Bettina Holtmann; John C Reed; Ulf R Rapp; Michael Sendtner
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.
Nature neuroscience 2005;8(9):1169-78.
2005: Eva M Lang; N Schlegel; Michael Sendtner; Esther Asan
Effects of root replantation and neurotrophic factor treatment on long-term motoneuron survival and axonal regeneration after C7 spinal root avulsion.
Experimental neurology 2005;194(2):341-54.
2005: Ralf A Linker; Michael Sendtner; Ralf Gold
Mechanisms of axonal degeneration in EAE--lessons from CNTF and MHC I knockout mice.
Journal of the neurological sciences 2005;233(1-2):167-72.
2005: Eva M Lang; Esther Asan; Nikolaus Plesnila; Gunther O Hofmann; Michael Sendtner
Motoneuron survival after C7 nerve root avulsion and replantation in the adult rabbit: effects of local ciliary neurotrophic factor and brain-derived neurotrophic factor application.
Plastic and reconstructive surgery 2005;115(7):2042-50.
2005: Bettina Holtmann; Stefan Wiese; Mohtashem Samsam; Katja Grohmann; Diane Pennica; Rudolf Martini; Michael Sendtner
Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(7):1778-87.
2005: Friedrich Metzger; Nadine Klapproth; Anna Kulik; Michael Sendtner; Klaus Ballanyi
Optical assessment of motoneuron function in a "twenty-four-hour" acute spinal cord slice model from fetal rats.
Journal of neuroscience methods 2005;141(2):309-20.
2005: Glen B Banks; Refik Kanjhan; Stefan Wiese; Matthias Kneussel; Loke M Wong; Gregory O'Sullivan; Michael Sendtner; Mark C Bellingham; Heinrich Betz; Peter G Noakes
Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(5):1249-59.
2005: Tobias Langenhan; Michael Sendtner; Bettina Holtmann; P Carroll; Esther Asan
Ciliary neurotrophic factor-immunoreactivity in olfactory sensory neurons.
Neuroscience 2005;134(4):1179-94.
2004: Matthias Hartmann; Tanja Brigadski; Kai S Erdmann; Bettina Holtmann; Michael Sendtner; Frank Narz; Volkmar Lessmann
Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor.
Journal of cell science 2004;117(Pt 24):5803-14.
2004: Katja Grohmann; wilfried rossoll; Igor Kobsar; Bettina Holtmann; Sibylle Jablonka; Carsten Wessig; Gisela Stoltenburg-Didinger; Utz Fischer; Christoph Hübner; Rudolf Martini; Michael Sendtner
Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1).
Human molecular genetics 2004;13(18):2031-42.
2004: Andreas Fischer; Nina Schumacher; Manfred Maier; Michael Sendtner; Manfred Gessler
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development.
Genes & development 2004;18(8):901-11.
2004: Mirko Hekman; Stefan Wiese; Renate Metz; Stefan Albert; Jakob Troppmair; Joachim Nickel; Michael Sendtner; Ulf R Rapp
Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites.
The Journal of biological chemistry 2004;279(14):14074-86.
2004: Alexandra Chittka; Juan Carlos Arevalo; Maria Rodriguez-Guzman; Pilar Pérez; Moses V Chao; Michael Sendtner
The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.
The Journal of cell biology 2004;164(7):985-96.
2004: Sibylle Jablonka; Stefan Wiese; Michael Sendtner
Axonal defects in mouse models of motoneuron disease.
Journal of neurobiology 2004;58(2):272-86.
2004: Stefan Wiese; M Beck; Christoph Karch; Michael Sendtner
Signalling mechanisms for survival of lesioned motoneurons.
Acta neurochirurgica. Supplement 2004;89():21-35.
2003: wilfried rossoll; Sibylle Jablonka; Catia Andreassi; Ann-Kathrin Kröning; Kathrin Karle; Umrao R Monani; Michael Sendtner
Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons.
The Journal of cell biology 2003;163(4):801-12.
2003: Sibylle Jablonka; Michael Sendtner
Molecular and cellular basis of spinal muscular atrophy.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2003;4(3):144-9.
2003: Thomas Naumann; Oliver Schnell; Qixia Zhi; Matthias Kirsch; Klaus Oliver Schubert; Michael Sendtner; Hans-Dieter Hofmann
Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection.
Brain pathology (Zurich, Switzerland) 2003;13(3):309-21.
2003: Kliment P Gatzinsky; Bettina Holtmann; Babak Daraie; Claes-Henric Berthold; Michael Sendtner
Early onset of degenerative changes at nodes of Ranvier in alpha-motor axons of Cntf null (-/-) mutant mice.
Glia 2003;42(4):340-9.
2003: Lutz Schomburg; Ulrich Schweizer; Bettina Holtmann; Leopold Flohé; Michael Sendtner; Josef Köhrle
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues.
The Biochemical journal 2003;370(Pt 2):397-402.
2003: Umrao R Monani; Matthew T Pastore; Tatiana O Gavrilina; Sibylle Jablonka; Thanh T Le; Catia Andreassi; Jennifer M DiCocco; Christian L Lorson; Elliot J Androphy; Michael Sendtner; Michael Podell; Arthur H M Burghes
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.
The Journal of cell biology 2003;160(1):41-52.
2003: Esther Asan; Tobias Langenhan; Bettina Holtmann; H Bock; Michael Sendtner; P Carroll
Ciliary neurotrophic factor in the olfactory bulb of rats and mice.
Neuroscience 2003;120(1):99-112.
2002: Heike Bommel; Gang Xie; wilfried rossoll; Stefan Wiese; Sibylle Jablonka; Thomas Boehm; Michael Sendtner
Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease.
The Journal of cell biology 2002;159(4):563-9.
2002: Hans Thoenen; Michael Sendtner
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches.
Nature neuroscience 2002;5 Suppl():1046-50.
2002: Sibylle Jablonka; Bettina Holtmann; Gunter Meister; Michael Bandilla; wilfried rossoll; Utz Fischer; Michael Sendtner
Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10126-31.
2002: Ralf A Linker; Mathias Mäurer; Stefanie Gaupp; Rudolf Martini; Bettina Holtmann; Ralf Giess; Peter Rieckmann; Hans Lassmann; Klaus V Toyka; Michael Sendtner; Ralf Gold
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation.
Nature medicine 2002;8(6):620-4.
2002: Ralf Giess; Bettina Holtmann; Massimiliano Braga; Tiemo Grimm; Bertram Müller-Myhsok; Klaus V Toyka; Michael Sendtner
Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene.
American journal of human genetics 2002;70(5):1277-86.
2002: Ralf Giess; Mathias Mäurer; Ralf A Linker; Ralf Gold; Monika Warmuth-Metz; Klaus V Toyka; Michael Sendtner; Peter Rieckmann
Association of a null mutation in the CNTF gene with early onset of multiple sclerosis.
Archives of neurology 2002;59(3):407-9.
2002: Ulrich Schweizer; Jennifer Gunnersen; Christoph Karch; Stefan Wiese; Bettina Holtmann; Kiyoshi Takeda; Shizuo Akira; Michael Sendtner
Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult.
The Journal of cell biology 2002;156(2):287-97.
2002: Andreas Fischer; Cornelia Leimeister; Christoph Winkler; Nina Schumacher; Barbara Klamt; Harun Elmasri; Christian Steidl; Manfred Maier; Klaus-Peter Knobeloch; Kerstin Amann; Armin Helisch; Michael Sendtner; Manfred Gessler
Hey bHLH factors in cardiovascular development.
Cold Spring Harbor symposia on quantitative biology 2002;67():63-70.
2002: wilfried rossoll; Ann-Kathrin Kröning; Uta-Maria Ohndorf; Clemens Steegborn; Sibylle Jablonka; Michael Sendtner
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?
Human molecular genetics 2002;11(1):93-105.
2001: BW Jordan; D Dinev; V LeMellay; Jakob Troppmair; R Gotz; L Wixler; Michael Sendtner; Stephan Ludwig; Ulf R Rapp
Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death.
The Journal of biological chemistry 2001;276(43):39985-9.
2001: Michael Sendtner
Molecular mechanisms in spinal muscular atrophy: models and perspectives.
Current opinion in neurology 2001;14(5):629-34.
2001: Katja Grohmann; Markus Schuelke; Alexander Diers; K Hoffmann; B Lucke; C Adams; Enrico Bertini; H Leonhardt-Horti; Francesco Muntoni; Robert Ouvrier; A Pfeufer; Rainer Rossi; Lionel Van Maldergem; Jo Wilmshurst; Thomas F Wienker; Michael Sendtner; Sabine Rudnik-Schöneborn; Klaus Zerres; Christoph Hübner
Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1.
Nature genetics 2001;29(1):75-7.
2001: M Beck; Christoph Karch; Stefan Wiese; Michael Sendtner
Motoneuron cell death and neurotrophic factors: basic models for development of new therapeutic strategies in ALS.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2001;2 Suppl 1():S55-68.
2001: Sibylle Jablonka; M Bandilla; Stefan Wiese; D Bühler; B Wirth; Michael Sendtner; Utz Fischer
Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy.
Human molecular genetics 2001;10(5):497-505.
2001: Ronald W Oppenheim; Stefan Wiese; David Prevette; M Armanini; S Wang; Lucien J Houenou; Bettina Holtmann; R Gotz; Diane Pennica; Michael Sendtner
Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(4):1283-91.
2001: Stefan Wiese; G Pei; Christoph Karch; Jakob Troppmair; Bettina Holtmann; Ulf R Rapp; Michael Sendtner
Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons.
Nature neuroscience 2001;4(2):137-42.
2001: Stefan Dazert; Christoph Aletsee; Dominik Brors; Claude Gravel; Michael Sendtner; A Ryan
In vivo adenoviral transduction of the neonatal rat cochlea and middle ear.
Hearing research 2001;151(1-2):30-40.
2000: Hiroshi Nishimune; Sophie Vasseur; Stefan Wiese; M C Birling; Bettina Holtmann; Michael Sendtner; Juan L Iovanna; Christopher E Henderson
Reg-2 is a motoneuron neurotrophic factor and a signalling intermediate in the CNTF survival pathway.
Nature cell biology 2000;2(12):906-14.
2000: Rudolf Götz; Christoph Karch; M R Digby; Jakob Troppmair; Ulf R Rapp; Michael Sendtner
The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells.
Human molecular genetics 2000;9(17):2479-89.
2000: Daniel D Coovert; Thanh T Le; Glenn E Morris; Nguyen Thi Man; M Kralewski; Michael Sendtner; Arthur H M Burghes
Does the survival motor neuron protein (SMN) interact with Bcl-2?
Journal of medical genetics 2000;37(7):536-9.
2000: Michael Sendtner; G Pei; M Beck; Ulrich Schweizer; Stefan Wiese
Developmental motoneuron cell death and neurotrophic factors.
Cell and tissue research 2000;301(1):71-84.
2000: G Ochs; Richard D Penn; M York; Ralf Giess; Marcus Beck; Jörg-Christian Tonn; J Haigh; E Malta; M Traub; Michael Sendtner; Klaus V Toyka
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2000;1(3):201-6.
2000: Sibylle Jablonka; wilfried rossoll; B Schrank; Michael Sendtner
The role of SMN in spinal muscular atrophy.
Journal of neurology 2000;247 Suppl 1():I37-42.
2000: Ralf Giess; M Beck; R Goetz; Roger M Nitsch; Klaus V Toyka; Michael Sendtner
Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis.
Neurology 2000;54(4):1003-5.
2000: Sibylle Jablonka; B Schrank; M Kralewski; wilfried rossoll; Michael Sendtner
Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III.
Human molecular genetics 2000;9(3):341-6.
2000: Umrao R Monani; Michael Sendtner; Daniel D Coovert; DONALD PARSONS; Catia Andreassi; Thanh T Le; Sibylle Jablonka; B Schrank; wilfried rossoll; W Rossol; Thomas W Prior; Glenn E Morris; Arthur H M Burghes
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Human molecular genetics 2000;9(3):333-9.
2000: Friedrich Metzger; Anna Kulik; Michael Sendtner; Klaus Ballanyi
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Journal of neurophysiology 2000;83(1):50-9.
1999: Stefan Wiese; M R Digby; Jennifer Gunnersen; Rudolf Götz; G Pei; Bettina Holtmann; John W Lowenthal; Michael Sendtner
The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons.
Nature neuroscience 1999;2(11):978-83.
1999: Bettina Holtmann; Jürgen Zielasek; Klaus V Toyka; Michael Sendtner
Comparative analysis of motoneuron loss and functional deficits in PMN mice: implications for human motoneuron disease.
Journal of the neurological sciences 1999;169(1-2):140-7.
1999: Ralf Giess; I Tanasescu; Thomas Steck; Michael Sendtner
Leukaemia inhibitory factor gene mutations in infertile women.
Molecular human reproduction 1999;5(6):581-6.
1999: Stefan Wiese; Friedrich Metzger; Bettina Holtmann; Michael Sendtner
The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons.
The European journal of neuroscience 1999;11(5):1668-76.
1999: Stefan Wiese; Friedrich Metzger; Bettina Holtmann; Michael Sendtner
Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration.
Acta neurochirurgica. Supplement 1999;73():31-9.
1998: Michel Cayouette; Darren Behn; Michael Sendtner; Pierre Lachapelle; Claude Gravel
Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9282-93.
1998: Friedrich Metzger; Stefan Wiese; Michael Sendtner
Effect of glutamate on dendritic growth in embryonic rat motoneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(5):1735-42.
1998: Ralf Giess; R Goetz; B Schrank; G Ochs; Michael Sendtner; Klaus V Toyka
Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease.
Muscle & nerve 1998;21(2):236-8.
1997: Michael Sendtner; Rudolf Götz; Bettina Holtmann; Hans Thoenen
Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(18):6999-7006.
1997: B Schrank; Rudolf Götz; Jennifer Gunnersen; J M Ure; Klaus V Toyka; A G Smith; Michael Sendtner
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9920-5.
1997: Claude Gravel; Rudolf Götz; A Lorrain; Michael Sendtner
Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons.
Nature medicine 1997;3(7):765-70.
1996: F Dittrich; G Ochs; A Grosse-Wilde; U Berweiler; Q Yan; J A Miller; Klaus V Toyka; Michael Sendtner
Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons.
Experimental neurology 1996;141(2):225-39.
1996: Ralf Gold; Jürgen Zielasek; J M Schröder; B Sellhaus; Jesse Cedarbaum; Hans-Peter Hartung; Michael Sendtner; Klaus V Toyka
Treatment with ciliary neurotrophic factor does not improve regeneration in experimental autoimmune neuritis of the Lewis rat.
Muscle & nerve 1996;19(9):1177-80.
1996: Michael Sendtner; Bettina Holtmann; R A Hughes
The response of motoneurons to neurotrophins.
Neurochemical research 1996;21(7):831-41.
1996: T M Michaelidis; Michael Sendtner; J D Cooper; M S Airaksinen; Bettina Holtmann; M Meyer; H Thoenen
Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development.
Neuron 1996;17(1):75-89.
1996: Michael Sendtner; Rudolf Götz; Bettina Holtmann; J L Escary; Y Masu; P Carroll; E Wolf; Gottfried Brem; P Brület; H Thoenen
Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF.
Current biology : CB 1996;6(6):686-94.
1996: Michael Sendtner
Neurotrophic factors for experimental treatment of motoneuron disease.
Progress in brain research 1996;109():365-71.
1996: Ben A Barres; J F Burne; Bettina Holtmann; H Thoenen; Michael Sendtner; Martin Raff
Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation.
Molecular and cellular neurosciences 1996;8(2-3):146-56.
1995: O Griesbeck; A S Parsadanian; Michael Sendtner; H Thoenen
Expression of neurotrophins in skeletal muscle: quantitative comparison and significance for motoneuron survival and maintenance of function.
Journal of neuroscience research 1995;42(1):21-33.
1994: Michael Sendtner; H Thoenen
Neurodegenerative disease. Oxidative stress and motorneuron disease.
Current biology : CB 1994;4(11):1036-9.
1994: Michael Sendtner; P Carroll; Bettina Holtmann; R A Hughes; H Thoenen
Ciliary neurotrophic factor.
Journal of neurobiology 1994;25(11):1436-53.
1994: Michael Sendtner; F Dittrich; R A Hughes; H Thoenen
Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications.
Journal of the neurological sciences 1994;124 Suppl():77-83.
1994: F Dittrich; H Thoenen; Michael Sendtner
Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat.
Annals of neurology 1994;35(2):151-63.
1993: R A Hughes; Michael Sendtner; H Thoenen
Members of several gene families influence survival of rat motoneurons in vitro and in vivo.
Journal of neuroscience research 1993;36(6):663-71.
1993: P Carroll; Michael Sendtner; M Meyer; H Thoenen
Rat ciliary neurotrophic factor (CNTF): gene structure and regulation of mRNA levels in glial cell cultures.
Glia 1993;9(3):176-87.
1993: Y Masu; E Wolf; Bettina Holtmann; Michael Sendtner; Gottfried Brem; H Thoenen
Disruption of the CNTF gene results in motor neuron degeneration.
Nature 1993;365(6441):27-32.
1993: Ben A Barres; MD Jacobson; R Schmid; Michael Sendtner; Martin Raff
Does oligodendrocyte survival depend on axons?
Current biology : CB 1993;3(8):489-97.
1993: R A Hughes; Michael Sendtner; mitchell goldfarb; Dan Lindholm; H Thoenen
Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons.
Neuron 1993;10(3):369-77.
1992: Michael Sendtner; Bettina Holtmann; Roland W Kolbeck; H Thoenen; Yves-Alain Barde
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section.
Nature 1992;360(6406):757-9.
1992: Michael Sendtner; H Schmalbruch; K A Stöckli; P Carroll; G W Kreutzberg; H Thoenen
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy.
Nature 1992;358(6386):502-4.
1992: Michael Sendtner; K A Stöckli; H Thoenen
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration.
The Journal of cell biology 1992;118(1):139-48.
1991: K A Stöckli; L E Lillien; M Näher-Noé; G Breitfeld; R A Hughes; Martin Raff; H Thoenen; Michael Sendtner
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain.
The Journal of cell biology 1991;115(2):447-59.
1991: Michael Sendtner; Y Arakawa; K A Stöckli; G W Kreutzberg; H Thoenen
Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival.
Journal of cell science. Supplement 1991;15():103-9.
1990: Y Arakawa; Michael Sendtner; H Thoenen
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(11):3507-15.
1990: L E Lillien; Michael Sendtner; Martin Raff
Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development.
The Journal of cell biology 1990;111(2):635-44.
1990: Michael Sendtner; G W Kreutzberg; H Thoenen
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.
Nature 1990;345(6274):440-1.
1989: K A Stöckli; F Lottspeich; Michael Sendtner; P Masiakowski; P Carroll; Rudolf Götz; Dan Lindholm; H Thoenen
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor.
Nature 1989;342(6252):920-3.
1989: S Saadat; Michael Sendtner; Hermann Rohrer
Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture.
The Journal of cell biology 1989;108(5):1807-16.
1989: Uwe Ernsberger; Michael Sendtner; Hermann Rohrer
Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor.
Neuron 1989;2(3):1275-84.
1988: S M Hughes; L E Lillien; Martin Raff; Hermann Rohrer; Michael Sendtner
Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture.
Nature 1988;335(6185):70-3.
1988: L E Lillien; Michael Sendtner; Hermann Rohrer; S M Hughes; Martin Raff
Type-2 astrocyte development in rat brain cultures is initiated by a CNTF-like protein produced by type-1 astrocytes.
Neuron 1988;1(6):485-94.
1988: Michael Sendtner; H Gnahn; Arun R. Wakade; H Thoenen
Is activation of the Na+K+ pump necessary for NGF-mediated neuronal survival?
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(2):458-62.