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Bruce Blazar
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93
Panoskaltsis-Mortari, Angela
65
Taylor, Patricia
45
Vallera, DA
37
Weisdorf, Daniel
33
McGlave, Philip
32
Ramsay, Norma
28
Murphy, William
24
Wagner, John
24
DeFor, Todd
20
Orchard, Paul
20
Miller, Jeffrey
20
Tolar, Jakub
16
Haddad, Imad
15
Kersey, John
14
Serody, Jonathan
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All Publications
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2009: Verneris Michael R; Brunstein Claudio G; Barker Juliet; MacMillan Margaret L; DeFor Todd; McKenna David H; Burke Michael J; Blazar Bruce R; Miller Jeffrey S; McGlave Philip B; Weisdorf Daniel J; Wagner John E
Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units.
Blood 2009;114(19):4293-9.
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2009: June Carl H; Blazar Bruce R; Riley James L
Engineering lymphocyte subsets: tools, trials and tribulations.
Nature reviews. Immunology 2009;9(10):704-16.
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2009: Tolar Jakub; Hippen Keli L; Blazar Bruce R
Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells.
British journal of haematology 2009;147(2):200-6.
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2009: Zhou Qing; Bucher Christoph; Munger Meghan E; Highfill Steven L; Tolar Jakub; Munn David H; Levine Bruce L; Riddle Megan; June Carl H; Vallera Daniel A; Weigel Brenda J; Blazar Bruce R
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia.
Blood 2009;114(18):3793-802.
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2009: Tomblyn Michael B; Arora Mukta; Baker K Scott; Blazar Bruce R; Brunstein Claudio G; Burns Linda J; DeFor Todd E; Dusenbery Kathryn E; Kaufman Dan S; Kersey John H; MacMillan Margaret L; McGlave Philip B; Miller Jeffrey S; Orchard Paul J; Slungaard Arne; Tomblyn Marcie R; Vercellotti Gregory M; Verneris Michael R; Wagner John E; Weisdorf Daniel J
Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(22):3634-41.
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2009: Barrett John; Blazar Bruce R
Genetic trickery--escape of leukemia from immune attack.
The New England journal of medicine 2009;361(5):524-5.
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2009: Highfill Steven L; Kelly Ryan M; O'Shaughnessy Matthew J; Zhou Qing; Xia Lily; Panoskaltsis-Mortari Angela; Taylor Patricia A; Tolar Jakub; Blazar Bruce R
Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming.
Blood 2009;114(3):693-701.
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2009: Wang Huan; Zhang Weiyu; Zhu Chuhong; Bucher Christoph; Blazar Bruce R; Zhang Chunxiang; Chen Jiang-Fan; Linden Joel; Wu Chaodong; Huo Yuqing
Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(7):1046-52.
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2009: Tchorsh-Yutsis Dalit; Hecht Gil; Aronovich Anna; Shezen Elias; Klionsky Yael; Rosen Chava; Bitcover Rivka; Eventov-Friedman Smadar; Katchman Helena; Cohen Sivan; Tal Orna; Milstein Oren; Yagita Hideo; Blazar Bruce R; Reisner Yair
Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression.
Diabetes 2009;58(7):1585-94.
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2009: Riley James L; June Carl H; Blazar Bruce R
Human T regulatory cell therapy: take a billion or so and call me in the morning.
Immunity 2009;30(5):656-65.
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2009: Brunstein Claudio G; Wagner John E; Weisdorf Daniel J; Cooley Sarah; Noreen Harriet; Barker Juliet N; DeFor Todd; Verneris Michael R; Blazar Bruce R; Miller Jeffrey S
Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity.
Blood 2009;113(22):5628-34.
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2009: Ghosh Arnab; Koestner Wolfgang; Hapke Martin; Schlaphoff Verena; Länger Florian; Baumann Rolf; Koenecke Christian; Cornberg Markus; Welte Karl; Blazar Bruce R; Sauer Martin G
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.
Blood 2009;113(18):4440-8.
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2009: Sarantopoulos Stefanie; Stevenson Kristen E; Kim Haesook T; Cutler Corey S; Bhuiya Nazmim S; Schowalter Michael; Ho Vincent T; Alyea Edwin P; Koreth John; Blazar Bruce R; Soiffer Robert J; Antin Joseph H; Ritz Jerome
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease.
Blood 2009;113(16):3865-74.
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2009: O'Shaughnessy M J; Vogtenhuber C; Sun K; Sitcheran R; Baldwin A S; Murphy W J; Dang L; Jaffee B; Palmer E; Serody J S; Blazar B R
Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(3):452-62.
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2009: MacMillan Margaret L; Weisdorf Daniel J; Brunstein Claudio G; Cao Qing; DeFor Todd E; Verneris Michael R; Blazar Bruce R; Wagner John E
Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors.
Blood 2009;113(11):2410-5.
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2009: Macmillan M L; Blazar B R; DeFor T E; Wagner J E
Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial.
Bone marrow transplantation 2009;43(6):447-54.
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2009: Brunstein Claudio G; Cantero Susana; Cao Qing; Majhail Navneet; McClune Brian; Burns Linda J; Tomblyn Marcie; Miller Jeffrey S; Blazar Bruce R; McGlave Philip B; Weisdorf Daniel J; Wagner John E
Promising progression-free survival for patients low and intermediate grade lymphoid malignancies after nonmyeloablative umbilical cord blood transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(2):214-22.
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2009: Gram Kendra; Yang Shuxia; Steiner Marie; Somani Arif; Hawgood Samuel; Blazar Bruce R; Panoskaltsis-Mortari Angela; Haddad Imad Y
Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice.
American journal of physiology. Lung cellular and molecular physiology 2009;296(2):L167-75.
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2009: Carlson Michael J; West Michelle L; Coghill James M; Panoskaltsis-Mortari Angela; Blazar Bruce R; Serody Jonathan S
In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations.
Blood 2009;113(6):1365-74.
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2009: Tolar Jakub; Ishida-Yamamoto Akemi; Riddle Megan; McElmurry Ron T; Osborn Mark; Xia Lily; Lund Troy; Slattery Catherine; Uitto Jouni; Christiano Angela M; Wagner John E; Blazar Bruce R
Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells.
Blood 2009;113(5):1167-74.
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2009: Lund Troy C; Glass Tiffany J; Tolar Jakub; Blazar Bruce R
Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio.
PloS one 2009;4(11):e7688.
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2008: Vogtenhuber Christine; O'Shaughnessy Matthew J; Vignali Dario A A; Blazar Bruce R
Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8767-75.
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2008: Anderson A; Martens C L; Hendrix R; Stempora L L; Miller W P; Hamby K; Russell M; Strobert E; Blazar B R; Pearson T C; Larsen C P; Kean L S
Expanded nonhuman primate tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(11):2252-64.
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2008: Chen Wei; Liang Xueqing; Peterson Amanda J; Munn David H; Blazar Bruce R
The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5396-404.
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2008: Hallett William H D; Ames Erik; Alvarez Maite; Barao Isabel; Taylor Patricia A; Blazar Bruce R; Murphy William J
Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(10):1088-99.
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2008: Tang Qin; Grzywacz Bartosz; Wang Hongbo; Kataria Nandini; Cao Qing; Wagner John E; Blazar Bruce R; Miller Jeffrey S; Verneris Michael R
Umbilical cord blood T cells express multiple natural cytotoxicity receptors after IL-15 stimulation, but only NKp30 is functional.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4507-15.
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2008: Kurtti Timothy J; Mattila Joshua T; Herron Michael J; Felsheim Roderick F; Baldridge Gerald D; Burkhardt Nicole Y; Blazar Bruce R; Hackett Perry B; Meyer Jason M; Munderloh Ulrike G
Transgene expression and silencing in a tick cell line: A model system for functional tick genomics.
Insect biochemistry and molecular biology 2008;38(10):963-8.
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2008: Hippen Keli L; Harker-Murray Paul; Porter Stephen B; Merkel Sarah C; Londer Aryel; Taylor Dawn K; Bina Megan; Panoskaltsis-Mortari Angela; Rubinstein Pablo; Van Rooijen Nico; Golovina Tatiana N; Suhoski Megan M; Miller Jeffrey S; Wagner John E; June Carl H; Riley James L; Blazar Bruce R
Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells.
Blood 2008;112(7):2847-57.
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2008: Taylor Patricia A; Ehrhardt Michael J; Lees Christopher J; Panoskaltsis-Mortari Angela; Krieg Arthur M; Sharpe Arlene H; Murphy William J; Serody Jonathan S; Hemmi Hiroaki; Akira Shizuo; Levy Robert B; Blazar Bruce R
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
Blood 2008;112(8):3508-16.
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2008: Levine John E; Blazar Bruce R; DeFor Todd; Ferrara James L M; Weisdorf Daniel J
Long-term follow-up of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT).
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(9):1017-21.
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2008: Peng Baowei; Ye Peiqing; Blazar Bruce R; Freeman Gordon J; Rawlings David J; Ochs Hans D; Miao Carol H
Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice.
Blood 2008;112(5):1662-72.
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2008: Golovina Tatiana N; Mikheeva Tatiana; Suhoski Megan M; Aqui Nicole A; Tai Victoria C; Shan Xiaochuan; Liu Ronghua; Balcarcel R Robert; Fisher Nancy; Levine Bruce L; Carroll Richard G; Warner Noel; Blazar Bruce R; June Carl H; Riley James L
CD28 costimulation is essential for human T regulatory expansion and function.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2855-68.
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2008: Osborn Mark J; McElmurry Ron T; Peacock Brandon; Tolar Jakub; Blazar Bruce R
Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1459-66.
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2008: Kelly Ryan M; Highfill Steven L; Panoskaltsis-Mortari Angela; Taylor Patricia A; Boyd Richard L; Holländer Georg A; Blazar Bruce R
Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation.
Blood 2008;111(12):5734-44.
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2008: Anderson Britt E; Taylor Patricia A; McNiff Jennifer M; Jain Dhanpat; Demetris Anthony J; Panoskaltsis-Mortari Angela; Ager Ann; Blazar Bruce R; Shlomchik Warren D; Shlomchik Mark J
Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells.
Blood 2008;111(10):5242-51.
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2008: Tian Chaorui; Yuan Xueli; Bagley Jessamyn; Blazar Bruce R; Sayegh Mohamed H; Iacomini John
Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells.
Clinical immunology (Orlando, Fla.) 2008;127(2):130-7.
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2008: Panoskaltsis-Mortari Angela; Taylor Patricia A; Riddle Megan J; Shlomchik Mark A; Blazar Bruce R
In situ identification of allospecific B cells using pentamers.
Blood 2008;111(7):3904-5.
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2008: Benedict Chris A; Loewendorf Andrea; Garcia Zacarias; Blazar Bruce R; Janssen Edith M
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4836-47.
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2008: Alderson Kory L; Zhou Qing; Berner Vanessa; Wilkins Danice E C; Weiss Jonathan M; Blazar Bruce R; Welniak Lisbeth A; Wiltrout Robert H; Redelman Doug; Murphy William J
Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):2981-8.
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2008: Huang Xin; Guo Hongfeng; Kang Johnthomas; Choi Suet; Zhou Tom C; Tammana Syam; Lees Christopher J; Li Zhong-Ze; Milone Michael; Levine Bruce L; Tolar Jakub; June Carl H; Scott McIvor R; Wagner John E; Blazar Bruce R; Zhou Xianzheng
Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):580-9.
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2008: Jasperson Lisa K; Bucher Christoph; Panoskaltsis-Mortari Angela; Taylor Patricia A; Mellor Andrew L; Munn David H; Blazar Bruce R
Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality.
Blood 2008;111(6):3257-65.
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2008: Ghosh Arnab; Wolenski Matthias; Klein Christoph; Welte Karl; Blazar Bruce R; Sauer Martin G
Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(2):121-31.
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2008: Anderson Britt E; Zheng Hong; Taylor Patricia A; Matte-Martone Catherine; McNiff Jeniffer M; Jain Dhanpat; Demetris Anthony J; Panoskaltsis-Mortari Angela; Ager Ann; Blazar Bruce R; Shlomchik Mark J; Shlomchik Warren D
Memory T cells in GVHD and GVL.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(1 Suppl 1):19-20.
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2008: Guimond Martin; Leonard Warren J; Spolski Rosanne; Rossi Simona W; Veenstra Rachelle G; Hollander Georg A; Mackall Crystal L; Blazar Bruce R
Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor.
Blood 2008;111(2):969-70.
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2007: Taylor Patricia A; Ehrhardt Michael J; Lees Christopher J; Tolar Jakub; Weigel Brenda J; Panoskaltsis-Mortari Angela; Serody Jonathan S; Brinkmann Volker; Blazar Bruce R
Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD).
Blood 2007;110(9):3480-8.
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2007: Tanaka Katsunori; Albin Monica J; Yuan Xueli; Yamaura Kazuhiro; Habicht Antje; Murayama Takaya; Grimm Martin; Waaga Ana Maria; Ueno Takuya; Padera Robert F; Yagita Hideo; Azuma Miyuki; Shin Tahiro; Blazar Bruce R; Rothstein David M; Sayegh Mohamed H; Najafian Nader
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5204-10.
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2007: Orchard Paul J; Blazar Bruce R; Wagner John; Charnas Lawrence; Krivit William; Tolar Jakub
Hematopoietic cell therapy for metabolic disease.
The Journal of pediatrics 2007;151(4):340-6.
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2007: Flynn Catherine M; Hirsch Betsy; Defor Todd; Barker Juliet N; Miller Jeffrey S; Wagner John E; Blazar Bruce R; Burns Linda J; Macmillan Margaret L; Arora Mukta; Weisdorf Daniel
Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical analysis.
American journal of hematology 2007;82(10):867-72.
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2007: Miller Jeffrey S; Weisdorf Daniel J; Burns Linda J; Slungaard Arne; Wagner John E; Verneris Michael R; Cooley Sarah; Wangen Rosanna; Fautsch Susan K; Nicklow Roby; Defor Todd; Blazar Bruce R
Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone.
Blood 2007;110(7):2761-3.
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2007: Panoskaltsis-Mortari Angela; Tram Kevin V; Price Andrew P; Wendt Christine H; Blazar Bruce R
A new murine model for bronchiolitis obliterans post-bone marrow transplant.
American journal of respiratory and critical care medicine 2007;176(7):713-23.
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2007: Brunstein Claudio G; Barker Juliet N; Weisdorf Daniel J; DeFor Todd E; Miller Jeffrey S; Blazar Bruce R; McGlave Philip B; Wagner John E
Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease.
Blood 2007;110(8):3064-70.
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2007: Sharma Madhav D; Baban Babak; Chandler Phillip; Hou De-Yan; Singh Nagendra; Yagita Hideo; Azuma Miyuki; Blazar Bruce R; Mellor Andrew L; Munn David H
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.
The Journal of clinical investigation 2007;117(9):2570-82.
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2007: Wang Hongbo; Grzywacz Bartosz; Sukovich David; McCullar Valarie; Cao Qing; Lee Alisa B; Blazar Bruce R; Cornfield David N; Miller Jeffrey S; Verneris Michael R
The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations.
Blood 2007;110(5):1530-9.
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2007: Tomblyn M; Burns L J; Blazar B; Wagner J; Lee C; Rogers T; McGlave P; Miller J S; Weisdorf D J
Difficult stem cell mobilization despite adequate CD34+ cell dose predicts shortened progression free and overall survival after autologous HSCT for lymphoma.
Bone marrow transplantation 2007;40(2):111-8.
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2007: Zayed Hatem; Xia Lily; Yerich Anton; Yant Stephen R; Kay Mark A; Puttaraju M; McGarrity Gerard J; Wiest David L; McIvor R Scott; Tolar Jakub; Blazar Bruce R
Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1273-9.
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2007: Seggewiss Ruth; Loré Karin; Guenaga F Javier; Pittaluga Stefania; Mattapallil Joseph; Chow Catherine K; Koup Richard A; Camphausen Kevin; Nason Martha C; Meier-Schellersheim Martin; Donahue Robert E; Blazar Bruce R; Dunbar Cynthia E; Douek Daniel C
Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques.
Blood 2007;110(1):441-9.
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2007: Yun Gong; Tolar Jakub; Yerich Anton K; Marsh Steven G E; Robinson James; Noreen Harriet; Blazar Bruce R; Miller Jeffrey S
A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity.
Clinical immunology (Orlando, Fla.) 2007;123(3):272-80.
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2007: O'Shaughnessy Matthew J; Chen Zong-Ming; Gramaglia Irene; Taylor Patricia A; Panoskaltsis-Mortari Angela; Vogtenhuber Christine; Palmer Ed; Grader-Beck Thomas; Boussiotis Vassiliki A; Blazar Bruce R
Elevation of intracellular cyclic AMP in alloreactive CD4(+) T Cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(5):530-42.
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2007: Rossi Simona W; Jeker Lukas T; Ueno Tomoo; Kuse Sachiyo; Keller Marcel P; Zuklys Saulius; Gudkov Andrei V; Takahama Yousuke; Krenger Werner; Blazar Bruce R; Holländer Georg A
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells.
Blood 2007;109(9):3803-11.
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2007: Tolar Jakub; Wang Xiaohong; Braunlin Elizabeth; McElmurry Ron T; Nakamura Yasuhiro; Bell Scott; Xia Lily; Zhang John; Hu Qingsong; Panoskaltsis-Mortari Angela; Zhang Jianyi; Blazar Bruce R
The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia.
Experimental hematology 2007;35(4):682-90.
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2007: Berner Vanessa; Liu Haiyan; Zhou Qing; Alderson Kory L; Sun Kai; Weiss Jonathan M; Back Timothy C; Longo Dan L; Blazar Bruce R; Wiltrout Robert H; Welniak Lisbeth A; Redelman Doug; Murphy William J
IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy.
Nature medicine 2007;13(3):354-60.
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2007: Min Dullei; Panoskaltsis-Mortari Angela; Kuro-O Makoto; Holländer Georg A; Blazar Bruce R; Weinberg Kenneth I
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging.
Blood 2007;109(6):2529-37.
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2007: Macmillan Margaret L; Couriel Daniel; Weisdorf Daniel J; Schwab Gisela; Havrilla Nancy; Fleming Thomas R; Huang Saling; Roskos Lorin; Slavin Shimon; Shadduck Richard K; Dipersio John; Territo Mary; Pavletic Steve; Linker Charles; Heslop Helen E; Joachim Deeg H; Blazar Bruce R
A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease.
Blood 2007;109(6):2657-62.
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2007: Markova M; Barker J N; Miller J S; Arora M; Wagner J E; Burns L J; MacMillan M L; Douek D; DeFor T; Tan Y; Repka T; Blazar B R; Weisdorf D J
Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial.
Bone marrow transplantation 2007;39(4):193-9.
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2007: Tolar Jakub; Nauta Alma J; Osborn Mark J; Panoskaltsis Mortari Angela; McElmurry Ron T; Bell Scott; Xia Lily; Zhou Ning; Riddle Megan; Schroeder Tania M; Westendorf Jennifer J; McIvor R Scott; Hogendoorn Pancras C W; Szuhai Karoly; Oseth Leann; Hirsch Betsy; Yant Stephen R; Kay Mark A; Peister Alexandra; Prockop Darwin J; Fibbe Willem E; Blazar Bruce R
Sarcoma derived from cultured mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2007;25(2):371-9.
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2007: Taylor Patricia A; Ehrhardt Michael J; Roforth Matthew M; Swedin Jessica M; Panoskaltsis-Mortari Angela; Serody Jonathan S; Blazar Bruce R
Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients.
Blood 2007;109(3):1307-15.
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2007: Serafini Marta; Dylla Scott J; Oki Masayuki; Heremans Yves; Tolar Jakub; Jiang Yuehua; Buckley Shannon M; Pelacho Beatriz; Burns Terry C; Frommer Sarah; Rossi Derrick J; Bryder David; Panoskaltsis-Mortari Angela; O'Shaughnessy Matthew J; Nelson-Holte Molly; Fine Gabriel C; Weissman Irving L; Blazar Bruce R; Verfaillie Catherine M
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.
The Journal of experimental medicine 2007;204(1):129-39.
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2007: Burchill Matthew A; Yang Jianying; Vogtenhuber Christine; Blazar Bruce R; Farrar Michael A
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):280-90.
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2007: Welniak Lisbeth A; Blazar Bruce R; Murphy William J
Immunobiology of allogeneic hematopoietic stem cell transplantation.
Annual review of immunology 2007;25():139-70.
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2006: Aronovich Anna; Tchorsh Dalit; Katchman Helena; Eventov-Friedman Smadar; Shezen Elias; Martinowitz Uri; Blazar Bruce R; Cohen Sivan; Tal Orna; Reisner Yair
Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19075-80.
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2006: Brenchley Jason M; Price David A; Schacker Timothy W; Asher Tedi E; Silvestri Guido; Rao Srinivas; Kazzaz Zachary; Bornstein Ethan; Lambotte Olivier; Altmann Daniel; Blazar Bruce R; Rodriguez Benigno; Teixeira-Johnson Leia; Landay Alan; Martin Jeffrey N; Hecht Frederick M; Picker Louis J; Lederman Michael M; Deeks Steven G; Douek Daniel C
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
Nature medicine 2006;12(12):1365-71.
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2006: Grzywacz Bartosz; Kataria Nandini; Sikora Magdalena; Oostendorp Robert A; Dzierzak Elaine A; Blazar Bruce R; Miller Jeffrey S; Verneris Michael R
Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.
Blood 2006;108(12):3824-33.
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2006: Blazar Bruce R; Weisdorf Daniel J; Defor Todd; Goldman Anne; Braun Thomas; Silver Samuel; Ferrara James L M
Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).
Blood 2006;108(9):3216-22.
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2006: Weigel Brenda J; Panoskaltsis-Mortari Angela; Diers Miechaleen; Garcia Melissa; Lees Chris; Krieg Arthur M; Chen Wei; Blazar Bruce R
Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses.
Experimental hematology 2006;34(10):1403-12.
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2006: Blaser Bradley W; Schwind Noah R; Karol Seth; Chang Dennis; Shin Samuel; Roychowdhury Sameek; Becknell Brian; Ferketich Amy K; Kusewitt Donna F; Blazar Bruce R; Caligiuri Michael A
Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity.
Blood 2006;108(7):2463-9.
-
2006: Porter Stephen B; Liu Baoling; Rogosheske John; Levine Bruce L; June Carl H; Kohl Virginia K; Wagner John E; Miller Jeffrey S; Blazar Bruce R
Suppressor function of umbilical cord blood-derived CD4+CD25+ T-regulatory cells exposed to graft-versus-host disease drugs.
Transplantation 2006;82(1):23-9.
-
2006: Eventov-Friedman Smadar; Tchorsh Dalit; Katchman Helena; Shezen Elias; Aronovich Anna; Hecht Gil; Dekel Benjamin; Rechavi Gideon; Blazar Bruce R; Feine Ilan; Tal Orna; Freud Enrique; Reisner Yair
Embryonic pig pancreatic tissue transplantation for the treatment of diabetes.
PLoS medicine 2006;3(7):e215.
-
2006: Steiner David; Brunicki Noga; Bachar-Lustig Esther; Taylor Patricia A; Blazar Bruce R; Reisner Yair
Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin.
Experimental hematology 2006;34(6):802-8.
-
2006: Tolar Jakub; O'shaughnessy Matthew J; Panoskaltsis-Mortari Angela; McElmurry Ron T; Bell Scott; Riddle Megan; McIvor R Scott; Yant Stephen R; Kay Mark A; Krause Diane; Verfaillie Catherine M; Blazar Bruce R
Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells.
Blood 2006;107(10):4182-8.
-
2006: Subramanian Indira V; Bui Nguyen Tri Minh; Truskinovsky Alexander M; Tolar Jakub; Blazar Bruce R; Ramakrishnan Sundaram
Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival.
Cancer research 2006;66(8):4319-28.
-
2006: Barao Isabel; Hanash Alan M; Hallett William; Welniak Lisbeth A; Sun Kai; Redelman Doug; Blazar Bruce R; Levy Robert B; Murphy William J
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5460-5.
-
2006: Kharbanda Sandhya; Panoskaltsis-Mortari Angela; Haddad Imad Y; Blazar Bruce R; Orchard Paul J; Cornfield David N; Grewal Satkiran S; Peters Charles; Regelmann Warren E; Milla Carlos E; Baker K Scott
Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(4):430-7.
-
2006: June Carl H; Blazar Bruce R
Clinical application of expanded CD4+25+ cells.
Seminars in immunology 2006;18(2):78-88.
-
2006: Gao Ning; Schwartzberg Pamela; Wilder Julie A; Blazar Bruce R; Yuan Dorothy
B cell induction of IL-13 expression in NK cells: role of CD244 and SLAM-associated protein.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2758-64.
-
2006: Zayed Hatem; McIvor R Scott; Wiest David L; Blazar Bruce R
In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement.
Human gene therapy 2006;17(2):158-66.
-
2006: Steiner David; Brunicki Noga; Blazar Bruce R; Bachar-Lustig Esther; Reisner Yair
Tolerance induction by third-party "off-the-shelf" CD4+CD25+ Treg cells.
Experimental hematology 2006;34(1):66-71.
-
2006: Braunlin Elizabeth; Mackey-Bojack Shannon; Panoskaltsis-Mortari Angela; Berry James M; McElmurry Ron T; Riddle Megan; Sun Li-Yan; Clarke Lorne A; Tolar Jakub; Blazar Bruce R
Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndrome.
Pediatric research 2006;59(1):27-32.
-
2006: Huang Xin; Wilber Andrew C; Bao Lei; Tuong Dong; Tolar Jakub; Orchard Paul J; Levine Bruce L; June Carl H; McIvor R Scott; Blazar Bruce R; Zhou Xianzheng
Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system.
Blood 2006;107(2):483-91.
-
2006: Welniak Lisbeth A; Kuprash Dmitry V; Tumanov Alexei V; Panoskaltsis-Mortari Angela; Blazar Bruce R; Sun Kai; Nedospasov Sergei A; Murphy William J
Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation.
Blood 2006;107(1):410-2.
-
2005: Miller Jeffrey S; Curtsinger Julie; Berthold Melinda; Malvey Kirsten; Bliss Robin L; Le Chap T; Fautsch Susan K; Dudek Arkadiusz Z; Blazar Bruce R; Panoskaltsis-Mortari Angela
Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation.
Clinical immunology (Orlando, Fla.) 2005;117(2):144-51.
-
2005: Li Lequn; Godfrey Wayne R; Porter Stephen B; Ge Ying; June Carle H; Blazar Bruce R; Boussiotis Vassiliki A
CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy.
Blood 2005;106(9):3068-73.
-
2005: Wysocki Christian A; Jiang Qi; Panoskaltsis-Mortari Angela; Taylor Patricia A; McKinnon Karen P; Su Lishan; Blazar Bruce R; Serody Jonathan S
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
Blood 2005;106(9):3300-7.
-
2005: Sun Kai; Wilkins Danice E C; Anver Miriam R; Sayers Thomas J; Panoskaltsis-Mortari Angela; Blazar Bruce R; Welniak Lisbeth A; Murphy William J
Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity.
Blood 2005;106(9):3293-9.
-
2005: Blazar Bruce R; Murphy William J
Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD).
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1461):1747-67.
-
2005: Blazar Bruce R
Manipulating and visualizing T-cell alloresponses.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(9):651-6.
-
2005: Osborn Mark J; Panoskaltsis-Mortari Angela; McElmurry Ron T; Bell Scott K; Vignali Dario A A; Ryan Martin D; Wilber Andrew C; McIvor R Scott; Tolar Jakub; Blazar Bruce R
A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):569-74.
-
2005: Sutherland Jayne S; Goldberg Gabrielle L; Hammett Maree V; Uldrich Adam P; Berzins Stuart P; Heng Tracy S; Blazar Bruce R; Millar Jeremy L; Malin Mark A; Chidgey Ann P; Boyd Richard L
Activation of thymic regeneration in mice and humans following androgen blockade.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2741-53.
-
2005: Zimmerman Zachary; Shatry Alwi; Deyev Vadim; Podack Eckhard; Mammolenti Michele; Blazar Bruce R; Yagita Hideo; Levy Robert B
Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(8):576-86.
-
2005: Quezada Sergio A; Bennett Kathy; Blazar Bruce R; Rudensky Alexander Y; Sakaguchi Shimon; Noelle Randolph J
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):771-9.
-
2005: Tolar Jakub; Osborn Mark; Bell Scott; McElmurry Ron; Xia Lily; Riddle Megan; Panoskaltsis-Mortari Angela; Jiang Yuehua; McIvor R Scott; Contag Christopher H; Yant Stephen R; Kay Mark A; Verfaillie Catherine M; Blazar Bruce R
Real-time in vivo imaging of stem cells following transgenesis by transposition.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(1):42-8.
-
2005: Tan Poh-Lin; Verneris Michael R; Charnas Lawrence R; Reck Samuel J; van Burik Jo-Anne H; Blazar Bruce R
Outcome of CNS and pulmonary enteroviral infections after hematopoietic cell transplantation.
Pediatric blood & cancer 2005;45(1):74-5.
-
2005: Wysocki Christian A; Panoskaltsis-Mortari Angela; Blazar Bruce R; Serody Jonathan S
Leukocyte migration and graft-versus-host disease.
Blood 2005;105(11):4191-9.
-
2005: Wacnik Paul W; Baker Christine M; Herron Michael J; Kren Betsy T; Blazar Bruce R; Wilcox George L; Hordinsky Maria K; Beitz Alvin J; Ericson Marna E
Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors.
Pain 2005;115(1-2):95-106.
-
2005: Shukla Mayank; Yang Shuxia; Milla Carlos; Panoskaltsis-Mortari Angela; Blazar Bruce R; Haddad Imad Y
Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L942-9.
-
2005: Gao Ning; Dang Tam; Dunnick Wesley A; Collins John T; Blazar Bruce R; Yuan Dorothy
Receptors and counterreceptors involved in NK-B cell interactions.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4113-9.
-
2005: Miller Jeffrey S; Soignier Yvette; Panoskaltsis-Mortari Angela; McNearney Sarah A; Yun Gong H; Fautsch Susan K; McKenna David; Le Chap; Defor Todd E; Burns Linda J; Orchard Paul J; Blazar Bruce R; Wagner John E; Slungaard Arne; Weisdorf Daniel J; Okazaki Ian J; McGlave Philip B
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer.
Blood 2005;105(8):3051-7.
-
2005: Taylor Patricia A; Panoskaltsis-Mortari Angela; Freeman Gordon J; Sharpe Arlene H; Noelle Randolph J; Rudensky Alexander Y; Mak Tak W; Serody Jonathan S; Blazar Bruce R
Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).
Blood 2005;105(8):3372-80.
-
2005: Anderson Britt E; McNiff Jennifer M; Jain Dhanpat; Blazar Bruce R; Shlomchik Warren D; Shlomchik Mark J
Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ.
Blood 2005;105(5):2227-34.
-
2005: Blazar Bruce R; Taylor Patricia A
Regulatory T cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(2 Suppl 2):46-9.
-
2005: Barker Juliet N; Weisdorf Daniel J; DeFor Todd E; Blazar Bruce R; McGlave Philip B; Miller Jeffrey S; Verfaillie Catherine M; Wagner John E
Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy.
Blood 2005;105(3):1343-7.
-
2005: Eikenberry Mark; Bartakova Hana; Defor Todd; Haddad Imad Y; Ramsay Norma K C; Blazar Bruce R; Milla Carlos E; Cornfield David N
Natural history of pulmonary complications in children after bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(1):56-64.
-
2005: Chen Wei; Chan Anissa S H; Dawson Amanda J; Liang Xueqing; Blazar Bruce R; Miller Jeffrey S
FLT3 ligand administration after hematopoietic cell transplantation increases circulating dendritic cell precursors that can be activated by CpG oligodeoxynucleotides to enhance T-cell and natural killer cell function.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(1):23-34.
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2005: Godfrey Wayne R; Spoden Darrin J; Ge Ying G; Baker Seth R; Liu Baoling; Levine Bruce L; June Carl H; Blazar Bruce R; Porter Stephen B
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function.
Blood 2005;105(2):750-8.
-
2005: Gendelman Maria; Halligan Nadine; Komorowski Richard; Logan Brent; Murphy William J; Blazar Bruce R; Pritchard Kirkwood A; Drobyski William R
Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration.
Blood 2005;105(1):428-31.
-
2004: Spielberger Ricardo; Stiff Patrick; Bensinger William; Gentile Teresa; Weisdorf Daniel; Kewalramani Tarun; Shea Thomas; Yanovich Saul; Hansen Keith; Noga Stephen; McCarty John; LeMaistre C Frederick; Sung Eric C; Blazar Bruce R; Elhardt Dieter; Chen Mon-Gy; Emmanouilides Christos
Palifermin for oral mucositis after intensive therapy for hematologic cancers.
The New England journal of medicine 2004;351(25):2590-8.
-
2004: Taylor Patricia A; Panoskaltsis-Mortari Angela; Swedin Jessica M; Lucas Philip J; Gress Ronald E; Levine Bruce L; June Carl H; Serody Jonathan S; Blazar Bruce R
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection.
Blood 2004;104(12):3804-12.
-
2004: Moseman E Ashley; Liang Xueqing; Dawson Amanda J; Panoskaltsis-Mortari Angela; Krieg Arthur M; Liu Yong-Jun; Blazar Bruce R; Chen Wei
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4433-42.
-
2004: Milla Carlos; Yang Shuxia; Cornfield David N; Brennan Marie-Luise; Hazen Stanley L; Panoskaltsis-Mortari Angela; Blazar Bruce R; Haddad Imad Y
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L706-14.
-
2004: Blazar Bruce R; Levy Robert B; Mak Tak W; Panoskaltsis-Mortari Angela; Muta Hiromi; Jones Monica; Roskos Melinda; Serody Jonathan S; Yagita Hideo; Podack Eckhard R; Taylor Patricia A
CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2933-41.
-
2004: Welniak Lisbeth A; Shorts Lynnette; Subleski Jeff; Blazar Bruce R; Wiltrout Robert H; Murphy William J
Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(8):534-9.
-
2004: Solovey Anna; Kollander Rahn; Shet Arun; Milbauer Liming C; Choong Stephana; Panoskaltsis-Mortari Angela; Blazar Bruce R; Kelm Robert J; Hebbel Robert P
Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin.
Blood 2004;104(3):840-6.
-
2004: Wysocki Christian A; Burkett Susan B; Panoskaltsis-Mortari Angela; Kirby Suzanne L; Luster Andrew D; McKinnon Karen; Blazar Bruce R; Serody Jonathan S
Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):845-54.
-
2004: Godfrey Wayne R; Ge Ying G; Spoden Darrin J; Levine Bruce L; June Carl H; Blazar Bruce R; Porter Stephen B
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures.
Blood 2004;104(2):453-61.
-
2004: Sauer Martin G; Ericson Marna E; Weigel Brenda J; Herron Michael J; Panoskaltsis-Mortari Angela; Kren Betsy T; Levine Bruce L; Serody Jon S; June Carl H; Taylor Patricia A; Blazar Bruce R
A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells.
Cancer research 2004;64(11):3914-21.
-
2004: Sun Kai; Welniak Lisbeth A; Panoskaltsis-Mortari Angela; O'Shaughnessy Matthew J; Liu Haiyan; Barao Isabel; Riordan William; Sitcheran Raquel; Wysocki Christian; Serody Jonathan S; Blazar Bruce R; Sayers Thomas J; Murphy William J
Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):8120-5.
-
2004: Panoskaltsis-Mortari Angela; Price Andrew; Hermanson John R; Taras Elizabeth; Lees Chris; Serody Jonathan S; Blazar Bruce R
In vivo imaging of graft-versus-host-disease in mice.
Blood 2004;103(9):3590-8.
-
2004: Kozel Thomas R; Murphy William J; Brandt Suzanne; Blazar Bruce R; Lovchik Julie A; Thorkildson Peter; Percival Ann; Lyons C Rick
mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):5042-7.
-
2004: Chen Wei; Antonenko Svetlana; Sederstrom Joel M; Liang Xueqing; Chan Anissa S H; Kanzler Holger; Blom Bianca; Blazar Bruce R; Liu Yong-Jun
Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors.
Blood 2004;103(7):2547-53.
-
2004: Welniak Lisbeth A; Wang Zhao; Sun Kai; Kuziel William; Anver Miriam R; Blazar Bruce R; Murphy William J
An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease.
Experimental hematology 2004;32(3):318-24.
-
2004: Chiorean Elena G; DeFor Todd E; Weisdorf Daniel J; Blazar Bruce R; McGlave Philip B; Burns Linda J; Brown Charlotte; Miller Jeffrey S
Donor chimerism does not predict response to donor lymphocyte infusion for relapsed chronic myelogenous leukemia after allogeneic hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(3):171-7.
-
2004: Panoskaltsis-Mortari Angela; Hermanson John R; Taras Elizabeth; Wangensteen O Douglas; Charo Israel F; Rollins Barrett J; Blazar Bruce R
Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells.
American journal of physiology. Lung cellular and molecular physiology 2004;286(2):L284-92.
-
2004: Godfrey Wayne R; Krampf Mark R; Taylor Patricia A; Blazar Bruce R
Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation.
Blood 2004;103(3):1158-65.
-
2004: Taylor Patricia A; Lees Christopher J; Fournier Sylvie; Allison James P; Sharpe Arlene H; Blazar Bruce R
B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections].
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):34-9.
-
2004: Wilcox Ryan A; Tamada Koji; Flies Dallas B; Zhu Gefeng; Chapoval Andrei I; Blazar Bruce R; Kast W Martin; Chen Lieping
Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo.
Blood 2004;103(1):177-84.
-
2003: Koh Crystal Y; Ortaldo John R; Blazar Bruce R; Bennett Michael; Murphy William J
NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade.
Blood 2003;102(12):4067-75.
-
2003: Jarvinen Lamis Z; Blazar Bruce R; Adeyi Oyedele A; Strom Terry B; Noelle Randolph J
CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance.
Transplantation 2003;76(9):1375-9.
-
2003: Quezada Sergio A; Fuller Bruce; Jarvinen Lamis Z; Gonzalez Mercedes; Blazar Bruce R; Rudensky Alexander Y; Strom Terry B; Noelle Randolph J
Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation.
Blood 2003;102(5):1920-6.
-
2003: Haddad Imad Y; Milla Carlos; Yang Shuxia; Panoskaltsis-Mortari Angela; Hawgood Samuel; Lacey David L; Blazar Bruce R
Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation.
American journal of physiology. Lung cellular and molecular physiology 2003;285(3):L602-10.
-
2003: Barker Juliet N; Weisdorf Daniel J; DeFor Todd E; Blazar Bruce R; Miller Jeffrey S; Wagner John E
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.
Blood 2003;102(5):1915-9.
-
2003: Weigel Brenda J; Rodeberg David A; Krieg Arthur M; Blazar Bruce R
CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):3105-14.
-
2003: Blazar Bruce R; Carreno Beatriz M; Panoskaltsis-Mortari Angela; Carter Laura; Iwai Yoshiko; Yagita Hideo; Nishimura Hiroyuki; Taylor Patricia A
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1272-7.
-
2003: Pan Yisheng; Luo Bin; Sozen Haken; Kalscheuer Hannes; Blazar Bruce R; Sutherland David E R; Hering Benhard J; Guo Zhiguang
Blockade of the CD40/CD154 pathway enhances T-cell-depleted allogeneic bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy.
Transplantation 2003;76(1):216-24.
-
2003: Burns L J; Weisdorf D J; DeFor T E; Vesole D H; Repka T L; Blazar B R; Burger S R; Panoskaltsis-Mortari A; Keever-Taylor C A; Zhang M-J; Miller J S
IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I/II trial.
Bone marrow transplantation 2003;32(2):177-86.
-
2003: Sayers Thomas J; Brooks Alan D; Koh Crystal Y; Ma Weihong; Seki Naoko; Raziuddin Arati; Blazar Bruce R; Zhang Xia; Elliott Peter J; Murphy William J
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.
Blood 2003;102(1):303-10.
-
2003: Chen Zong-ming; O'Shaughnessy Matthew J; Gramaglia Irene; Panoskaltsis-Mortari Angela; Murphy William J; Narula Satwant; Roncarolo Maria G; Blazar Bruce R
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.
Blood 2003;101(12):5076-83.
-
2003: Blazar Bruce R; Sharpe Arlene H; Chen Andy I; Panoskaltsis-Mortari Angela; Lees Christopher; Akiba Hisaya; Yagita Hideo; Killeen Nigel; Taylor Patricia A
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.
Blood 2003;101(9):3741-8.
-
2003: Panoskaltsis-Mortari Angela; Hermanson John R; Taras Elizabeth; Wangensteen O Douglas; Serody Jonathan S; Blazar Bruce R
Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1 alpha (CCL3) after allogeneic BMT in mice.
Blood 2003;101(9):3714-21.
-
2003: Guo Zhiguang; Wu Tao; Sozen Hakan; Pan Yisheng; Heuss Neal; Kalscheuer Hannes; Sutherland David E R; Blazar Bruce R; Hering Bernhard J
A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic NOD mice.
Transplantation 2003;75(7):909-15.
-
2003: Prlic Martin; Blazar Bruce R; Farrar Michael A; Jameson Stephen C
In vivo survival and homeostatic proliferation of natural killer cells.
The Journal of experimental medicine 2003;197(8):967-76.
-
2003: Murphy William J; Welniak Lisbeth; Back Timothy; Hixon Julie; Subleski Jeff; Seki Naoko; Wigginton Jon M; Wilson Susan E; Blazar Bruce R; Malyguine Anatoli M; Sayers Thomas J; Wiltrout Robert H
Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2727-33.
-
2002: Weigel Brenda J; Nath Narender; Taylor Patricia A; Panoskaltsis-Mortari Angela; Chen Wei; Krieg Arthur M; Brasel Kenneth; Blazar Bruce R
Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses.
Blood 2002;100(12):4169-76.
-
2002: Waldschmidt Thomas J; Panoskaltsis-Mortari Angela; McElmurry Ronald T; Tygrett Lorraine T; Taylor Patricia A; Blazar Bruce R
Abnormal T cell-dependent B-cell responses in SCID mice receiving allogeneic bone marrow in utero. Severe combined immune deficiency.
Blood 2002;100(13):4557-64.
-
2002: Harmala Lisa A E; Ingulli Elizabeth G; Curtsinger Julie M; Lucido Michelle M; Schmidt Clint S; Weigel Brenda J; Blazar Bruce R; Mescher Matthew F; Pennell Christopher A
The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5622-9.
-
2002: Gonzalez Mercedes; Quezada Sergio A; Blazar Bruce R; Panoskaltsis-Mortari Angela; Rudensky Alexander Y; Noelle Randolph J
The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5581-9.
-
2002: Antin Joseph H; Weisdorf Daniel; Neuberg Donna; Nicklow Roberta; Clouthier Shawn; Lee Stephanie J; Alyea Edwin; McGarigle Carol; Blazar Bruce R; Sonis Stephen; Soiffer Robert J; Ferrara James L M
Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation.
Blood 2002;100(10):3479-82.
-
2002: Davies Stella M; Ruggieri Loredana; DeFor Todd; Wagner John E; Weisdorf Daniel J; Miller Jeffrey S; Velardi Andrea; Blazar Bruce R
Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.
Blood 2002;100(10):3825-7.
-
2002: Taylor Patricia A; Lees Christopher J; Wilson Jessica M; Ehrhardt Michael J; Campbell Matthew T; Noelle Randolph J; Blazar Bruce R
Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions.
Blood 2002;100(9):3400-7.
-
2002: Yang Shuxia; Milla Carlos; Panoskaltsis-Mortari Angela; Hawgood Samuel; Blazar Bruce R; Haddad Imad Y
Surfactant protein A decreases lung injury and mortality after murine marrow transplantation.
American journal of respiratory cell and molecular biology 2002;27(3):297-305.
-
2002: Wagner John E; Barker Juliet N; DeFor Todd E; Baker K Scott; Blazar Bruce R; Eide Cindy; Goldman Anne; Kersey John; Krivit William; MacMillan Margaret L; Orchard Paul J; Peters Charles; Weisdorf Daniel J; Ramsay Norma K C; Davies Stella M
Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival.
Blood 2002;100(5):1611-8.
-
2002: Rossi Simona; Blazar Bruce R; Farrell Catherine L; Danilenko Dimitry M; Lacey David L; Weinberg Kenneth I; Krenger Werner; Holländer Georg A
Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease.
Blood 2002;100(2):682-91.
-
2002: Taylor Patricia A; Friedman Thea M; Korngold Robert; Noelle Randolph J; Blazar Bruce R
Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell.
Blood 2002;99(12):4601-9.
-
2002: Min Dullei; Taylor Patricia A; Panoskaltsis-Mortari Angela; Chung Brile; Danilenko Dimitry M; Farrell Catherine; Lacey David L; Blazar Bruce R; Weinberg Kenneth I
Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation.
Blood 2002;99(12):4592-600.
-
2002: Yang Shuxia; Panoskaltsis-Mortari Angela; Shukla Mayank; Blazar Bruce R; Haddad Imad Y
Exuberant inflammation in nicotinamide adenine dinucleotide phosphate-oxidase-deficient mice after allogeneic marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5840-7.
-
2002: Orchard Paul J; Blazar Bruce R; Burger Scott; Levine Bruce; Basso Lisa; Nelson David M K; Gordon Keith; McIvor R Scott; Wagner John E; Miller Jeffrey S
Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor.
Human gene therapy 2002;13(8):979-88.
-
2002: Taylor Patricia A; Lees Christopher J; Blazar Bruce R
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality.
Blood 2002;99(10):3493-9.
-
2002: Battaglia Manuela; Blazar Bruce R; Roncarolo Maria-Grazia
The puzzling world of murine T regulatory cells.
Microbes and infection / Institut Pasteur 2002;4(5):559-66.
-
2002: LaBelle James L; Hanke Carrie A; Blazar Bruce R; Truitt Robert L
Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia.
Blood 2002;99(6):2146-53.
-
2002: Jin Ni; Chen Wei; Blazar Bruce R; Ramakrishnan S; Vallera Daniel A
Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor--immunotoxin target gene.
Human gene therapy 2002;13(4):497-508.
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2002: Taylor Patricia A; McElmurry Ronald T; Lees Christopher J; Harrison David E; Blazar Bruce R
Allogenic fetal liver cells have a distinct competitive engraftment advantage over adult bone marrow cells when infused into fetal as compared with adult severe combined immunodeficient recipients.
Blood 2002;99(5):1870-2.
-
2002: Tamada Koji; Tamura Hideto; Flies Dallas; Fu Yang-Xin; Celis Esteban; Pease Larry R; Blazar Bruce R; Chen Lieping
Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease.
The Journal of clinical investigation 2002;109(4):549-57.
-
2002: Johnson Bryon D; Taylor Patricia A; Stankowski Marja C; Talib Sohel; Hearst John E; Blazar Bruce R
Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(11):581-7.
-
2002: MacMillan Margaret L; Weisdorf Daniel J; Wagner John E; DeFor Todd E; Burns Linda J; Ramsay Norma K C; Davies Stella M; Blazar Bruce R
Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(7):387-94.
-
2002: Hixon Julie A; Anver Miriam R; Blazar Bruce R; Panoskaltsis-Mortari Angela; Wiltrout Robert H; Murphy William J
Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(6):316-25.
-
2002: MacMillan Margaret L; Weisdorf Daniel J; Davies Stella M; DeFor Todd E; Burns Linda J; Ramsay Norma K C; Wagner John E; Blazar Bruce R
Early antithymocyte globulin therapy improves survival in patients with steroid-resistant acute graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(1):40-6.
-
2002: Koh Crystal Y; Raziuddin Arati; Welniak Lisbeth A; Blazar Bruce R; Bennett Michael; Murphy William J
NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(1):17-25.
-
2001: Prlic M; Blazar B R; Khoruts A; Zell T; Jameson S C
Homeostatic expansion occurs independently of costimulatory signals.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5664-8.
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2001: Ziegler T R; Panoskaltsus-Mortari A; Gu L H; Jonas C R; Farrell C L; Lacey D L; Jones D P; Blazar B R
Regulation of glutathione redox status in lung and liver by conditioning regimens and keratinocyte growth factor in murine allogeneic bone marrow transplantation.
Transplantation 2001;72(8):1354-62.
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2001: Deeg H J; Blazar B R; Bolwell B J; Long G D; Schuening F; Cunningham J; Rifkin R M; Abhyankar S; Briggs A D; Burt R; Lipani J; Roskos L K; White J M; Havrilla N; Schwab G; Heslop H E
Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL.
Blood 2001;98(7):2052-8.
-
2001: Yang S; Porter V A; Cornfield D N; Milla C; Panoskaltsis-Mortari A; Blazar B R; Haddad I Y
Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L922-30.
-
2001: Blazar B R; Lindberg F P; Ingulli E; Panoskaltsis-Mortari A; Oldenborg P A; Iizuka K; Yokoyama W M; Taylor P A
CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells.
The Journal of experimental medicine 2001;194(4):541-9.
-
2001: Blazar B R; Krieg A M; Taylor P A
Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients.
Blood 2001;98(4):1217-25.
-
2001: Taylor P A; Lees C J; Waldmann H; Noelle R J; Blazar B R
Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions.
Blood 2001;98(2):467-74.
-
2001: Taylor P A; Noelle R J; Blazar B R
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade.
The Journal of experimental medicine 2001;193(11):1311-8.
-
2001: Yang S; Milla C; Panoskaltsis-Mortari A; Ingbar D H; Blazar B R; Haddad I Y
Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice.
American journal of respiratory cell and molecular biology 2001;24(5):527-36.
-
2001: Koh C Y; Blazar B R; George T; Welniak L A; Capitini C M; Raziuddin A; Murphy W J; Bennett M
Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo.
Blood 2001;97(10):3132-7.
-
2001: Pawlowska A B; Hashino S; McKenna H; Weigel B J; Taylor P A; Blazar B R
In vitro tumor-pulsed or in vivo Flt3 ligand-generated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-transplanted mice.
Blood 2001;97(5):1474-82.
-
2001: Blazar B R; Kwon B S; Panoskaltsis-Mortari A; Kwak K B; Peschon J J; Taylor P A
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3174-83.
-
2001: Panoskaltsis-Mortari A; Hermanson J R; Haddad I Y; Wangensteen O D; Blazar B R
Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(7):368-77.
-
2001: Arora M; Wagner J E; Davies S M; Blazar B R; Defor T; Enright H; Miller W J; Weisdorf D F
Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(5):265-73.
-
2001: Hixon J A; Blazar B R; Anver M R; Wiltrout R H; Murphy W J
Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(3):136-43.
-
2000: Panoskaltsis-Mortari A; Taylor P A; Rubin J S; Uren A; Welniak L A; Murphy W J; Farrell C L; Lacey D L; Blazar B R
Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury.
Blood 2000;96(13):4350-6.
-
2000: Yang S; Panoskaltsis-Mortari A; Ingbar D H; Matalon S; Zhu S; Resnik E R; Farrell C L; Lacey D L; Blazar B R; Haddad I Y
Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice.
American journal of respiratory and critical care medicine 2000;162(5):1884-90.
-
2000: Blazar B R; Lees C J; Martin P J; Noelle R J; Kwon B; Murphy W; Taylor P A
Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):4901-9.
-
2000: Baker K S; Bostrom B; DeFor T; Ramsay N K; Woods W G; Blazar B R
Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia.
Bone marrow transplantation 2000;26(6):607-14.
-
2000: Panoskaltsis-Mortari A; Strieter R M; Hermanson J R; Fegeding K V; Murphy W J; Farrell C L; Lacey D L; Blazar B R
Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation.
Blood 2000;96(3):834-9.
-
2000: Sayers T J; Brooks A D; Seki N; Smyth M J; Yagita H; Blazar B R; Malyguine A M
T cell lysis of murine renal cancer: multiple signaling pathways for cell death via Fas.
Journal of leukocyte biology 2000;68(1):81-6.
-
2000: Panoskaltsis-Mortari A; Ingbar D H; Jung P; Haddad I Y; Bitterman P B; Wangensteen O D; Farrell C L; Lacey D L; Blazar B R
KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT.
American journal of physiology. Lung cellular and molecular physiology 2000;278(5):L988-99.
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2000: Weisdorf D J; DeFor T; Nichol J; Panoskaltsis-Mortari A; Blazar B R
Thrombopoietic cytokines in relation to platelet recovery after bone marrow transplantation.
Bone marrow transplantation 2000;25(7):711-5.
-
2000: Vallera D A; Jin N; Baldrica J M; Panoskaltsis-Mortari A; Chen S Y; Blazar B R
Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.
Cancer research 2000;60(4):976-84.
-
2000: Taylor P A; Panoskaltsis-Mortari A; Noelle R J; Blazar B R
Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):612-22.
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1999: Zeller J C; Panoskaltsis-Mortari A; Murphy W J; Ruscetti F W; Narula S; Roncarolo M G; Blazar B R
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3684-91.
-
1999: Vallera D A; Seo S Y; Panoskaltsis-Mortari A; Griffin J D; Blazar B R
Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice.
Protein engineering 1999;12(9):779-85.
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1999: Haddad I Y; Panoskaltsis-Mortari A; Ingbar D H; Resnik E R; Yang S; Farrell C L; Lacey D L; Cornfield D N; Blazar B R
Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice.
The American journal of physiology 1999;277(2 Pt 1):L391-400.
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1999: Haddad I Y; Ingbar D H; Panoskaltsis-Mortari A; Blazar B R
Activated alveolar macrophage-derived nitric oxide predicts the development of lung damage after marrow transplantation in mice.
Chest 1999;116(1 Suppl):37S.
-
1999: Baker K S; Roncarolo M G; Peters C; Bigler M; DeFor T; Blazar B R
High spontaneous IL-10 production in unrelated bone marrow transplant recipients is associated with fewer transplant-related complications and early deaths.
Bone marrow transplantation 1999;23(11):1123-9.
-
1999: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Sharpe A H; Vallera D A
Opposing roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in murine recipients of MHC disparate T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6368-77.
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1999: Haddad I Y; Panoskaltsis-Mortari A; Ingbar D H; Yang S; Milla C E; Blazar B R
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation.
American journal of respiratory cell and molecular biology 1999;20(6):1125-35.
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1999: Buhlmann J E; Gonzalez M; Ginther B; Panoskaltsis-Mortari A; Blazar B R; Greiner D L; Rossini A A; Flavell R; Noelle R J
Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4373-6.
-
1998: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Yagita H; Bromberg J S; Vallera D A
A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation.
Blood 1998;92(11):4453-63.
-
1998: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Narula S K; Smith S R; Roncarolo M G; Vallera D A
Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease.
Transplantation 1998;66(9):1220-9.
-
1998: Panoskaltsis-Mortari A; Lacey D L; Vallera D A; Blazar B R
Keratinocyte growth factor administered before conditioning ameliorates graft-versus-host disease after allogeneic bone marrow transplantation in mice.
Blood 1998;92(10):3960-7.
-
1998: Blazar B R; Taylor P A; McElmurry R; Tian L; Panoskaltsis-Mortari A; Lam S; Lees C; Waldschmidt T; Vallera D A
Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via In utero or postnatal transfer.
Blood 1998;92(10):3949-59.
-
1998: Murphy W J; Welniak L A; Taub D D; Wiltrout R H; Taylor P A; Vallera D A; Kopf M; Young H; Longo D L; Blazar B R
Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice.
The Journal of clinical investigation 1998;102(9):1742-8.
-
1998: Panoskaltsis-Mortari A; Egeler R M; Yaeger T M; Yoneji S; Schmitz L; Lilly F; Nesbit M E; Blazar B R
Genetic and immunological parameters governing in vivo susceptibility/resistance to retrovirally induced murine malignant histiocytosis.
Journal of leukocyte biology 1998;64(4):441-50.
-
1998: Blazar B R; Taylor P A; Noelle R J; Vallera D A
CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses.
The Journal of clinical investigation 1998;102(3):473-82.
-
1998: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Vallera D A
Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production of Th1 or Th1 cytotoxic cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5355-65.
-
1997: Blazar B R; Jenkins M K; Taylor P A; White J; Panoskaltsis-Mortari A; Korngold R; Vallera D A
Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5821-33.
-
1997: Pawlowska A B; Blazar B R; Angelucci E; Baronciani D; Shu X O; Bostrom B
Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia.
Bone marrow transplantation 1997;20(11):915-20.
-
1997: Weisdorf D; Miller J; Verfaillie C; Burns L; Wagner J; Blazar B; Davies S; Miller W; Hannan P; Steinbuch M; Ramsay N; McGlave P
Cytokine-primed bone marrow stem cells vs. peripheral blood stem cells for autologous transplantation: a randomized comparison of GM-CSF vs. G-CSF.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1997;3(4):217-23.
-
1997: Miller J S; Tessmer-Tuck J; Blake N; Lund J; Scott A; Blazar B R; Orchard P J
Endogenous IL-2 production by natural killer cells maintains cytotoxic and proliferative capacity following retroviral-mediated gene transfer.
Experimental hematology 1997;25(11):1140-8.
-
1997: Blazar B R; Taylor P A; Boyer M W; Panoskaltsis-Mortari A; Allison J P; Vallera D A
CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3460-73.
-
1997: Vallera D A; Panoskaltsis-Mortari A; Blazar B R
Renal dysfunction accounts for the dose limiting toxicity of DT390anti-CD3sFv, a potential new recombinant anti-GVHD immunotoxin.
Protein engineering 1997;10(9):1071-6.
-
1997: Panoskaltsis-Mortari A; Taylor P A; Yaeger T M; Wangensteen O D; Bitterman P B; Ingbar D H; Vallera D A; Blazar B R
The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide.
The Journal of clinical investigation 1997;100(5):1015-27.
-
1997: Blazar B R; Taylor P A; Vallera D A
CD4+ and CD8+ T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients.
Transplantation 1997;64(4):571-6.
-
1997: Blazar B R; Korngold R; Vallera D A
Recent advances in graft-versus-host disease (GVHD) prevention.
Immunological reviews 1997;157():79-109.
-
1997: Boyer M W; Vallera D A; Taylor P A; Gray G S; Katsanis E; Gorden K; Orchard P J; Blazar B R
The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.
Blood 1997;89(9):3477-85.
-
1997: Miller J S; Tessmer-Tuck J; Pierson B A; Weisdorf D; McGlave P; Blazar B R; Katsanis E; Verfaillie C; Lebkowski J; Radford J; Burns L J
Low dose subcutaneous interleukin-2 after autologous transplantation generates sustained in vivo natural killer cell activity.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1997;3(1):34-44.
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1997: Davies S M; Wagner J E; Defor T; Blazar B R; Katsanis E; Kersey J H; Orchard P J; McGlave P B; Weisdorf D J; Ramsay N K
Unrelated donor bone marrow transplantation for children and adolescents with aplastic anaemia or myelodysplasia.
British journal of haematology 1997;96(4):749-56.
-
1997: Weisdorf D J; Verfaille C M; Miller W J; Blazar B R; Perry E; Shu X O; Daniels K; Hannan P; Ramsay N K; Kersey J H; McGlave P B
Autologous bone marrow versus non-mobilized peripheral blood stem cell transplantation for lymphoid malignancies: a prospective, comparative trial.
American journal of hematology 1997;54(3):202-8.
-
1997: Davies S M; Wagner J E; Shu X O; Blazar B R; Katsanis E; Orchard P J; Kersey J H; Dusenbery K E; Weisdorf D J; McGlave P B; Ramsay N K
Unrelated donor bone marrow transplantation for children with acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(2):557-65.
-
1997: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Buhlman J; Xu J; Flavell R A; Korngold R; Noelle R; Vallera D A
Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):29-39.
-
1996: Davies S M; Wagner J E; Weisdorf D J; Shu X O; Blazar B R; Enright H; McGlave P B; Ramsay N K
Unrelated donor bone marrow transplantation for hematological malignancies-current status.
Leukemia & lymphoma 1996;23(3-4):221-6.
-
1996: Blazar B R; Sharpe A H; Taylor P A; Panoskaltsis-Mortari A; Gray G S; Korngold R; Vallera D A
Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3250-9.
-
1996: Dusenbery K E; Steinbuch M; McGlave P B; Ramsay N K; Blazar B R; Neglia J P; Litz C; Kersey J H; Woods W G
Autologous bone marrow transplantation in acute myeloid leukemia: the University of Minnesota experience.
International journal of radiation oncology, biology, physics 1996;36(2):335-43.
-
1996: Vallera D A; Taylor P A; Widmer M B; Blazar B R
Interleukin-1 alpha-mediated promotion of long-term alloengraftment and short-term neutrophil expansion does not require the presence of either donor or host T cells.
Transplantation 1996;62(5):636-42.
-
1996: Katsanis E; Xu Z; Panoskaltsis-Mortari A; Weisdorf D J; Widmer M B; Blazar B R
IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice.
Transplantation 1996;62(6):872-5.
-
1996: Vallera D A; Panoskaltsis-Mortari A; Jost C; Ramakrishnan S; Eide C R; Kreitman R J; Nicholls P J; Pennell C; Blazar B R
Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.
Blood 1996;88(6):2342-53.
-
1996: Chan C H; Blazar B R; Greenfield L; Kreitman R J; Vallera D A
Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells.
Blood 1996;88(4):1445-56.
-
1996: Ochs L A; Blazar B R; Roy J; Rest E B; Weisdorf D J
Cytokine expression in human cutaneous chronic graft-versus-host disease.
Bone marrow transplantation 1996;17(6):1085-92.
-
1996: Blazar B R; Taylor P A; Bluestone J A; Vallera D A
Murine gamma/delta-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens.
Blood 1996;87(10):4463-72.
-
1996: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Sehgal S; Vallera D A
In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A.
Blood 1996;87(9):4001-9.
-
1996: Orchard P J; Katsanis E; Boyer M; May C; McIvor R S; Blazar B R
Interleukin-2 secretion by transduced and unselected BDL-2 lymphoma results in increased survival in mice with previously established disseminated disease.
Cancer biotherapy & radiopharmaceuticals 1996;11(2):155-64.
-
1996: Bausero M A; Panoskaltsis-Mortari A; Blazar B R; Katsanis E
Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-gamma.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(2):113-24.
-
1996: Katsanis E; Bausero M A; Panoskaltsis-Mortari A; Dancisak B B; Xu Z; Orchard P J; Davis C G; Blazar B R
Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity.
Cancer gene therapy 1996;3(2):75-82.
-
1996: Blazar B R; Roopenian D C; Taylor P A; Christianson G J; Panoskaltsis-Mortari A; Vallera D A
Lack of GVHD across classical, single minor histocompatibiliTy (miH) locus barriers in mice.
Transplantation 1996;61(4):619-24.
-
1996: Chiang K Y; Weisdorf D J; Davies S M; Enright H; Kersey J H; McGlave P B; Miller W; Ramsay N K; Steinbuch M; Wagner J E; Blazar B R
Outcome of second bone marrow transplantation following a uniform conditioning regimen as therapy for malignant relapse.
Bone marrow transplantation 1996;17(1):39-42.
-
1996: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Barrett T A; Bluestone J A; Vallera D A
Lethal murine graft-versus-host disease induced by donor gamma/delta expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens.
Blood 1996;87(2):827-37.
-
1995: Vallera D A; Taylor P A; Vannice J L; Panoskaltsis-Mortari A; Blazar B R
Interleukin-1 or tumor necrosis factor-alpha antagonists do not inhibit graft-versus-host disease induced across the major histocompatibility barrier in mice.
Transplantation 1995;60(11):1371-4.
-
1995: Blazar B R; Brennan C A; Broxmeyer H E; Shultz L D; Vallera D A
Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo.
Experimental hematology 1995;23(13):1397-406.
-
1995: Vallera D A; Taylor P A; Panoskaltsis-Mortari A; Blazar B R
Therapy for ongoing graft-versus-host disease induced across the major or minor histocompatibility barrier in mice with anti-CD3F(ab')2-ricin toxin A chain immunotoxin.
Blood 1995;86(11):4367-75.
-
1995: Blazar B R; Taylor P A; Vallera D A
In utero transfer of adult bone marrow cells into recipients with severe combined immunodeficiency disorder yields lymphoid progeny with T- and B-cell functional capabilities.
Blood 1995;86(11):4353-66.
-
1995: Chan C H; Blazar B R; Eide C R; Kreitman R J; Vallera D A
A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells.
Blood 1995;86(7):2732-40.
-
1995: Roy J; Blazar B R; Ochs L; Weisdorf D J
The tissue expression of cytokines in human acute cutaneous graft-versus-host disease.
Transplantation 1995;60(4):343-8.
-
1995: Davies S M; Shu X O; Blazar B R; Filipovich A H; Kersey J H; Krivit W; McCullough J; Miller W J; Ramsay N K; Segall M
Unrelated donor bone marrow transplantation: influence of HLA A and B incompatibility on outcome.
Blood 1995;86(4):1636-42.
-
1995: Orchard P J; McIvor R S; Singh H A; Blazar B R
GM-CSF-induced internal autocrine proliferation occurs in a compartment outside of the endoplasmic reticulum.
Experimental hematology 1995;23(7):573-82.
-
1995: Bhatia R; McGlave P B; Dewald G W; Blazar B R; Verfaillie C M
Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: role of malignant stromal macrophages.
Blood 1995;85(12):3636-45.
-
1995: Boyer M W; Orchard P J; Gorden K B; Anderson P M; Mclvor R S; Blazar B R
Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia.
Blood 1995;85(9):2498-506.
-
1995: Blazar B R; Taylor P A; Panoskaltsis-Mortari A; Gray G S; Vallera D A
Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts.
Blood 1995;85(9):2607-18.
-
1995: Katsanis E; Xu Z; Bausero M A; Dancisak B B; Gorden K B; Davis G; Gray G S; Orchard P J; Blazar B R
B7-1 expression decreases tumorigenicity and induces partial systemic immunity to murine neuroblastoma deficient in major histocompatibility complex and costimulatory molecules.
Cancer gene therapy 1995;2(1):39-46.
-
1995: Blazar B R; Taylor P A; Smith S; Vallera D A
Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts.
Blood 1995;85(3):842-51.
-
1995: Dusenbery K E; Daniels K A; McClure J S; McGlave P B; Ramsay N K; Blazar B R; Neglia J P; Kersey J H; Woods W G
Randomized comparison of cyclophosphamide-total body irradiation versus busulfan-cyclophosphamide conditioning in autologous bone marrow transplantation for acute myeloid leukemia.
International journal of radiation oncology, biology, physics 1995;31(1):119-28.
-
1994: Blazar B R; Taylor P A; Gray G S; Vallera D A
The role of T cell subsets in regulating the in vivo efficacy of CTLA4-Ig in preventing graft-versus-host disease in recipients of fully MHC or multiple minor histocompatibility-disparate donor inocula.
Transplantation 1994;58(12):1422-6.
-
1994: Katsanis E; Xu Z; Anderson P M; Dancisak B B; Bausero M A; Weisdorf D J; Blazar B R; Ochoa A C
Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of effector cells with potent anti-lymphoma activity.
Bone marrow transplantation 1994;14(4):563-72.
-
1994: Weisdorf D; Katsanis E; Verfaillie C; Ramsay N K; Haake R; Garrison L; Blazar B R
Interleukin-1 alpha administered after autologous transplantation: a phase I/II clinical trial.
Blood 1994;84(6):2044-9.
-
1994: Hings I M; Severson R; Filipovich A H; Blazar B R; Kersey J H; Ramsay N K; McGlave P B; Weisdorf D J
Treatment of moderate and severe acute GVHD after allogeneic bone marrow transplantation.
Transplantation 1994;58(4):437-42.
-
1994: Blazar B R; Taylor P A; Fitzsimmons W E; Vallera D A
FK506 inhibits graft-versus-host disease and bone marrow graft rejection in murine recipients of MHC disparate donor grafts by interfering with mature peripheral T cell expansion post-transplantation.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1836-46.
-
1994: Davies S M; Weisdorf D J; Haake R J; Kersey J H; McGlave P B; Ramsay N K; Blazar B R
Second infusion of bone marrow for treatment of graft failure after allogeneic bone marrow transplantation.
Bone marrow transplantation 1994;14(1):73-7.
-
1994: Blazar B R; Taylor P A; Linsley P S; Vallera D A
In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice.
Blood 1994;83(12):3815-25.
-
1994: Lane P H; Mauer S M; Blazar B R; Ramsay N K; Kashtan C E
Outcome of dialysis for acute renal failure in pediatric bone marrow transplant patients.
Bone marrow transplantation 1994;13(5):613-7.
-
1994: Katsanis E; Weisdorf D J; Xu Z; Dancisak B B; Halet M L; Blazar B R
Infusions of interleukin-1 alpha after autologous transplantation for Hodgkin's disease and non-Hodgkin's lymphoma induce effector cells with antilymphoma cytolytic activity.
Journal of clinical immunology 1994;14(3):205-11.
-
1994: Blazar B R; Taylor P A; Vallera D A
In vivo or in vitro anti-CD3 epsilon chain monoclonal antibody therapy for the prevention of lethal murine graft-versus-host disease across the major histocompatibility barrier in mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3665-74.
-
1994: Ochs L A; Miller W J; Filipovich A H; Haake R J; McGlave P B; Blazar B R; Ramsay N K; Kersey J H; Weisdorf D J
Predictive factors for chronic graft-versus-host disease after histocompatible sibling donor bone marrow transplantation.
Bone marrow transplantation 1994;13(4):455-60.
-
1994: Katsanis E; Blazar B R; Bausero M A; Gunther R; Anderson P M
Retroperitoneal inoculation of murine neuroblastoma results in a reliable model for evaluation of the antitumor immune response.
Journal of pediatric surgery 1994;29(4):538-42.
-
1994: Katsanis E; Orchard P J; Bausero M A; Gorden K B; McIvor R S; Blazar B R
Interleukin-2 gene transfer into murine neuroblastoma decreases tumorigenicity and enhances systemic immunity causing regression of preestablished retroperitoneal tumors.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;15(2):81-90.
-
1994: Katsanis E; Bausero M A; Xu H; Orchard P J; Xu Z; McIvor R S; Brian A A; Blazar B R
Transfection of the mouse ICAM-1 gene into murine neuroblastoma enhances susceptibility to lysis, reduces in vivo tumorigenicity and decreases ICAM-2-dependent killing.
Cancer immunology, immunotherapy : CII 1994;38(2):135-41.
-
1994: Blazar B R; Taylor P A; Sehgal S N; Vallera D A
Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow.
Blood 1994;83(2):600-9.
-
1994: Davies S M; Ramsay N K; Haake R J; Kersey J H; Weisdorf D J; McGlave P B; Blazar B R
Comparison of engraftment in recipients of matched sibling of unrelated donor marrow allografts.
Bone marrow transplantation 1994;13(1):51-7.
-
1993: Weisdorf D; Filipovich A; McGlave P; Ramsay N; Kersey J; Miller W; Blazar B
Combination graft-versus-host disease prophylaxis using immunotoxin (anti-CD5-RTA [Xomazyme-CD5]) plus methotrexate and cyclosporine or prednisone after unrelated donor marrow transplantation.
Bone marrow transplantation 1993;12(5):531-6.
-
1993: Blazar B R; Taylor P A; Snover D C; Sehgal S N; Vallera D A
Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(10):5726-41.
-
1993: Kersey J; Filipovich A; McGlave P; Woods W; Weisdorf D; Neglia J; Dusenbery K; Blazar B; Nesbit M; Ramsay N
Donor and host influences in bone marrow transplantation for immunodeficiency disease and leukemia.
Seminars in hematology 1993;30(4 Suppl 4):105-8; discussion 109.
-
1993: Vallera D A; Taylor P A; Aukerman S L; Blazar B R
Antitumor protection from the murine T-cell leukemia/lymphoma EL4 by the continuous subcutaneous coadministration of recombinant macrophage-colony stimulating factor and interleukin-2.
Cancer research 1993;53(18):4273-80.
-
1993: Howson-Jan K; Matloub Y H; Vallera D A; Blazar B R
In utero engraftment of fully H-2-incompatible versus congenic adult bone marrow transferred into nonanemic or anemic murine fetal recipients.
Transplantation 1993;56(3):709-16.
-
1993: Orchard P J; Detrick R A; Gorden K; Dunbar C E; Vallera D A; Taylor P; McIvor R S; Blazar B R
Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.
Experimental hematology 1993;21(9):1245-54.
-
1993: Blazar B R; Taylor P A; Sehgal S N; Vallera D A
Rapamycin prolongs survival of murine recipients of fully allogeneic donor grafts when administered during the graft-versus-host disease process.
Annals of the New York Academy of Sciences 1993;685():73-85.
-
1993: Weisdorf D J; Anderson P M; Blazar B R; Uckun F M; Kersey J H; Ramsay N K
Interleukin 2 immediately after autologous bone marrow transplantation for acute lymphoblastic leukemia--a phase I study.
Transplantation 1993;55(1):61-6.
-
1993: Blazar B R; Taylor P A; Snover D C; Bluestone J A; Vallera D A
Nonmitogenic anti-CD3F(ab')2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(1):265-77.
-
1993: Blazar B R; Taylor P A; Vallera D A
In vivo T-cell receptor ligation facilitates alloengraftment and prevents lethal graft-versus-host disease (GVHD) in mice.
Bone marrow transplantation 1993;12 Suppl 3():S38-40.
-
1992: Blazar B R; Widmer M B; Taylor P A; Vallera D A
Promotion of murine marrow alloengraftment and hematopoietic recovery across the major histocompatibility barrier by administration of recombinant human interleukin-1 alpha.
Blood 1992;80(6):1614-22.
-
1992: Roy J; McGlave P B; Filipovich A H; Miller W J; Blazar B R; Ramsay N K; Kersey J H; Weisdorf D J
Acute graft-versus-host disease following unrelated donor marrow transplantation: failure of conventional therapy.
Bone marrow transplantation 1992;10(1):77-82.
-
1992: Vallera D A; Carroll S F; Brief S; Blazar B R
Anti-CD3 immunotoxin prevents low-dose STZ/interferon-induced autoimmune diabetes in mouse.
Diabetes 1992;41(4):457-64.
-
1992: Blazar B R; Aukerman S L; Vallera D A
Effect of recombinant human macrophage colony-stimulating factor in irradiated murine recipients of T-cell-depleted allogeneic or non-depleted syngeneic bone marrow transplants.
Blood 1992;79(6):1636-42.
-
1992: Orchard P J; Dahl N; Aukerman S L; Blazar B R; Key L L
Circulating macrophage colony-stimulating factor is not reduced in malignant osteopetrosis.
Experimental hematology 1992;20(1):103-5.
-
1991: Warwick A; Ferrieri P; Burke B; Blazar B R
Presumptive invasive Chrysosporium infection in a bone marrow transplant recipient.
Bone marrow transplantation 1991;8(4):319-22.
-
1991: Blazar B R; Hirsch R; Gress R E; Carroll S F; Vallera D A
In vivo administration of anti-CD3 monoclonal antibodies or immunotoxins in murine recipients of allogeneic T cell-depleted marrow for the promotion of engraftment.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(5):1492-503.
-
1991: Weisdorf D; Hakke R; Blazar B; Miller W; McGlave P; Ramsay N; Kersey J; Filipovich A
Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation.
Transplantation 1991;51(6):1197-203.
-
1991: Vallera D A; Schmidberger H; Buchsbaum D J; Everson P; Snover D C; Blazar B R
Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of established graft-versus-host disease induced across the major histocompatibility barrier.
Cancer research 1991;51(7):1891-7.
-
1991: Schmidberger H; Buchsbaum D J; Blazar B R; Everson P; Vallera D A
Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of the T cell lymphoma EL4.
Cancer research 1991;51(7):1883-90.
-
1991: Vallera D A; Carroll S F; Snover D C; Carlson G J; Blazar B R
Toxicity and efficacy of anti-T-cell ricin toxin A chain immunotoxins in a murine model of established graft-versus-host disease induced across the major histocompatibility barrier.
Blood 1991;77(1):182-94.
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1991: Katsanis E; Bausero M A; Ochoa A C; Loeffler C M; Blazar B R; Leonard A S; Anderson P M
Importance in timing of cyclophosphamide on the enhancement of interleukin-2-induced cytolysis.
Cancer immunology, immunotherapy : CII 1991;34(2):74-8.
-
1990: Filipovich A H; Vallera D; McGlave P; Polich D; Gajl-Peczalska K; Haake R; Lasky L; Blazar B; Ramsay N K; Kersey J
T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation. The correlation between residual CD5 negative T cells and subsequent graft-versus-host disease.
Transplantation 1990;50(3):410-5.
-
1990: Blazar B R; Filipovich A H
Identification of transfused blood cells in children with severe combined immunodeficiency syndrome by analysis of multiple cell lineages using restriction fragment length polymorphisms.
Bone marrow transplantation 1990;5(5):327-33.
-
1990: Weisdorf D; Haake R; Blazar B; Miller W; McGlave P; Ramsay N; Kersey J; Filipovich A
Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome.
Blood 1990;75(4):1024-30.
-
1990: Blazar B R; Thiele D L; Vallera D A
Pretreatment of murine donor grafts with L-leucyl-L-leucine methyl ester: elimination of graft-versus-host disease without detrimental effects on engraftment.
Blood 1990;75(3):798-805.
-
1989: Blazar B R; Widmer M B; Cosman D; Sassenfeld H M; Vallera D A
Improved survival and leukocyte reconstitution without detrimental effects on engraftment in murine recipients of human recombinant granulocyte colony-stimulating factor after transplantation of T-cell-depleted histoincompatible bone marrow.
Blood 1989;74(6):2264-9.
-
1989: Vallera D A; Blazar B R
T cell depletion for graft-versus-host-disease prophylaxis. A perspective on engraftment in mice and humans.
Transplantation 1989;47(5):751-60.
-
1989: Weisdorf D; Arthur D; Rank J; Blazar B; Gajl-Peczalska K; Snover D
Gastric recurrence of acute lymphoblastic leukaemia mimicking graft-versus-host disease.
British journal of haematology 1989;71(4):559-61.
-
1989: Lasky L C; Van Buren N; Weisdorf D J; Filipovich A; McGlave P; Kersey J H; McCullough J; Ramsay N K; Blazar B R
Successful allogeneic cryopreserved marrow transplantation.
Transfusion 1989;29(2):182-4.
-
1989: Blazar B R; Kersey J H; McGlave P B; Vallera D A; Lasky L C; Haake R J; Bostrom B; Weisdorf D R; Epstein C; Ramsay N K
In vivo administration of recombinant human granulocyte/macrophage colony-stimulating factor in acute lymphoblastic leukemia patients receiving purged autografts.
Blood 1989;73(3):849-57.
-
1989: Anderson P M; Blazar B R; Bach F H; Ochoa A C
Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(4):1383-94.
-
1988: Vallera D A; Blazar B R
Depressed leukocyte reconstitution and engraftment in murine recipients of T cell-depleted histoincompatible marrow pretreated with interleukin 3.
Transplantation 1988;46(4):616-20.
-
1988: Blazar B R; Widmer M B; Soderling C C; Gillis S; Vallera D A
Enhanced survival but reduced engraftment in murine recipients of recombinant granulocyte/macrophage colony-stimulating factor following transplantation of T-cell-depleted histoincompatible bone marrow.
Blood 1988;72(4):1148-54.
-
1988: Blazar B R; Widmer M B; Kersey J H; Ramsay N K; McGlave P B; Urdal D L; Gillis S; Henney C; Vallera D A
Recombinant granulocyte/macrophage-colony stimulating factor in human and murine bone marrow transplantation.
Behring Institute Mitteilungen 1988;(83):170-80.
-
1988: Blazar B R; Soderling C C; Robison L L; Vallera D A
Short-course total-lymphoid irradiation combined with total-body irradiation to facilitate engraftment of T cell-depleted marrow across a major histocompatibility barrier in mice.
Transplantation 1988;46(2):324-7.
-
1988: Blazar B R; Soderling C C; Koo G C; Vallera D A
Absence of a facilitory role for NK 1.1-positive donor cells in engraftment across a major histocompatibility barrier in mice.
Transplantation 1988;45(5):876-83.
-
1988: Shapiro R S; McClain K; Frizzera G; Gajl-Peczalska K J; Kersey J H; Blazar B R; Arthur D C; Patton D F; Greenberg J S; Burke B
Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation.
Blood 1988;71(5):1234-43.
-
1988: Blazar B R; Widmer M B; Soderling C C; Urdal D L; Gillis S; Robison L L; Vallera D A
Augmentation of donor bone marrow engraftment in histoincompatible murine recipients by granulocyte/macrophage colony-stimulating factor.
Blood 1988;71(2):320-8.
-
1987: McGlave P; Scott E; Ramsay N; Arthur D; Blazar B; McCullough J; Kersey J
Unrelated donor bone marrow transplantation therapy for chronic myelogenous leukemia.
Blood 1987;70(3):877-81.
-
1987: Filipovich A H; Vallera D A; Youle R J; Haake R; Blazar B R; Arthur D; Neville D M; Ramsay N K; McGlave P; Kersey J H
Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow.
Transplantation 1987;44(1):62-9.
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