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Sally Serneels

Research Profile

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Kristel Sleegers; Nathalie Brouwers; Sebastian Maurer-Stroh; M A van Es; P Van Damme; P W J van Vught; Julie van der Zee; Sally Serneels; Tim De Pooter; Marleen Van den Broeck; Marc Cruts; J Schymkowitz; Peter De Jonghe; Frederic Rousseau; L H van den Berg; Wim Robberecht; Christine Van Broeckhoven
Progranulin genetic variability contributes to amyotrophic lateral sclerosis.
Nathalie Brouwers; Karen Nuytemans; Julie van der Zee; Ilse Gijselinck; Sebastiaan Engelborghs; Jessie Theuns; Samir Kumar-Singh; Barbara A Pickut; Philippe Pals; Bart Dermaut; Veerle Bogaerts; Tim De Pooter; Sally Serneels; Marleen Van den Broeck; Ivy Cuijt; Maria Mattheijssens; Karin Peeters; Raf Sciot; Jean-Jacques Martin; Patrick Cras; Patrick Santens; Rik Vandenberghe; Peter Paul De Deyn; Marc Cruts; Christine Van Broeckhoven; Kristel Sleegers
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.
Sebastiaan Engelborghs; Kristel Sleegers; Patrick Cras; Nathalie Brouwers; Sally Serneels; Evelyn De Leenheir; Jean-Jacques Martin; Eugeen Vanmechelen; Christine Van Broeckhoven; Peter Paul De Deyn
No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.

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All Publications

2008: Kristel Sleegers; Nathalie Brouwers; Sebastian Maurer-Stroh; M A van Es; P Van Damme; P W J van Vught; Julie van der Zee; Sally Serneels; Tim De Pooter; Marleen Van den Broeck; Marc Cruts; J Schymkowitz; Peter De Jonghe; Frederic Rousseau; L H van den Berg; Wim Robberecht; Christine Van Broeckhoven
Progranulin genetic variability contributes to amyotrophic lateral sclerosis.
Neurology 2008;71(4):253-9.
2007: Nathalie Brouwers; Karen Nuytemans; Julie van der Zee; Ilse Gijselinck; Sebastiaan Engelborghs; Jessie Theuns; Samir Kumar-Singh; Barbara A Pickut; Philippe Pals; Bart Dermaut; Veerle Bogaerts; Tim De Pooter; Sally Serneels; Marleen Van den Broeck; Ivy Cuijt; Maria Mattheijssens; Karin Peeters; Raf Sciot; Jean-Jacques Martin; Patrick Cras; Patrick Santens; Rik Vandenberghe; Peter Paul De Deyn; Marc Cruts; Christine Van Broeckhoven; Kristel Sleegers
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.
Archives of neurology 2007;64(10):1436-46.
2007: Sebastiaan Engelborghs; Kristel Sleegers; Patrick Cras; Nathalie Brouwers; Sally Serneels; Evelyn De Leenheir; Jean-Jacques Martin; Eugeen Vanmechelen; Christine Van Broeckhoven; Peter Paul De Deyn
No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.
Brain : a journal of neurology 2007;130(Pt 9):2320-6.
2006: Nathalie Brouwers; Kristel Sleegers; Sebastiaan Engelborghs; Veerle Bogaerts; Sally Serneels; Kenan Kamali; Ellen Corsmit; Evelyn De Leenheir; Jean-Jacques Martin; Peter Paul De Deyn; Christine Van Broeckhoven; Jessie Theuns
Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease.
Brain : a journal of neurology 2006;129(Pt 11):2984-91.
2005: Nathalie Verpoorten; Kristien Verhoeven; Stefan Weckx; An Jacobs; Sally Serneels; Jurgen Del-Favero; Chantal Ceuterick; Dirk R Van Bockstaele; Zwi N Berneman; Ludo Van Den Bosch; Wim Robberecht; Lucilla Nobbio; Angelo Schenone; Eric Dessaud; Odile deLapeyrière; Danny Huylebroeck; An Zwijsen; Peter De Jonghe; Vincent Timmerman
Synaptopodin and 4 novel genes identified in primary sensory neurons.
Molecular and cellular neurosciences 2005;30(3):316-25.
2005: Samir Kumar-Singh; Daniel Pirici; Eileen McGowan; Sally Serneels; Chantal Ceuterick; John Hardy; karen duff; dennis dickson; Christine Van Broeckhoven
Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls.
The American journal of pathology 2005;167(2):527-43.
2003: Sebastiaan Engelborghs; Bart Dermaut; Johan Goeman; Jos Saerens; Peter Mariën; Barbara A Pickut; Marleen Van den Broeck; Sally Serneels; Marc Cruts; Christine Van Broeckhoven; Peter Paul De Deyn
Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects.
Journal of neurology, neurosurgery, and psychiatry 2003;74(8):1148-51.
2002: Samir Kumar-Singh; Ann Julliams; Rony Nuydens; Chantal Ceuterick; Christine Labeur; Sally Serneels; Krist'l Vennekens; Peter Van Osta; Hugo Geerts; Bart De Strooper; Christine Van Broeckhoven
In vitro studies of Flemish, Dutch, and wild-type beta-amyloid provide evidence for two-staged neurotoxicity.
Neurobiology of disease 2002;11(2):330-40.
2002: Samir Kumar-Singh; Patrick Cras; Rong Wang; John M Kros; John C van Swieten; Ursula Lübke; Chantal Ceuterick; Sally Serneels; Krist'l Vennekens; Jean-Pierre Timmermans; Eric Van Marck; Jean-Jacques Martin; C.M. Duijn; Christine Van Broeckhoven
Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric.
The American journal of pathology 2002;161(2):507-20.
2002: Gerwin Roks; Marc Cruts; Jeanine J Houwing-Duistermaat; Bart Dermaut; Sally Serneels; L M Havekes; Albert Hofman; Monique Breteler; Christine Van Broeckhoven; C.M. Duijn
Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study.
American journal of medical genetics 2002;114(5):570-3.
2001: Bart Dermaut; Gerwin Roks; Jessie Theuns; Rosa Rademakers; Jeanine J Houwing-Duistermaat; Sally Serneels; Albert Hofman; Monique Breteler; Marc Cruts; Christine Van Broeckhoven; C.M. Duijn
Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's disease.
Journal of neurology 2001;248(11):935-9.
2001: Chris De Jonghe; Cary Esselens; Samir Kumar-Singh; Katleen Craessaerts; Sally Serneels; F Checler; Willem ANNAERT; Christine Van Broeckhoven; Bart De Strooper
Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.
Human molecular genetics 2001;10(16):1665-71.
2001: Martine Jacquier; D Arango; E Villareal; O Torres; M L Serrano; Marc Cruts; P Montañes; C Cano; M N Rodriguez; Sally Serneels; Christine Van Broeckhoven
APOE epsilon4 and Alzheimer's disease: positive association in a Colombian clinical series and review of the Latin-American studies.
Arquivos de neuro-psiquiatria 2001;59(1):11-7.
2000: Jessie Theuns; Jurgen Del-Favero; Bart Dermaut; C.M. Duijn; Hubert Backhovens; Marleen Van den Broeck; Sally Serneels; Ellen Corsmit; Christine Van Broeckhoven; Marc Cruts
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression.
Human molecular genetics 2000;9(3):325-31.
1999: Gerwin Roks; Bart Dermaut; Peter Heutink; Ann Julliams; Hubert Backhovens; M Van de Broeck; Sally Serneels; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn; Marc Cruts
Mutation screening of the tau gene in patients with early-onset Alzheimer's disease.
Neuroscience letters 1999;277(2):137-9.
1999: C.M. Duijn; Marc Cruts; Jessie Theuns; G Van Gassen; Hubert Backhovens; Marleen Van den Broeck; A Wehnert; Sally Serneels; Albert Hofman; Christine Van Broeckhoven
Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease in a population-based sample.
European journal of human genetics : EJHG 1999;7(7):801-6.
1998: Marc Cruts; C.M. Duijn; Hubert Backhovens; Marleen Van den Broeck; A Wehnert; Sally Serneels; R Sherrington; Michael Hutton; John Hardy; Peter St George-Hyslop; Albert Hofman; Christine Van Broeckhoven
Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease.
Human molecular genetics 1998;7(1):43-51.