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Mariangela Serra

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Katsuhiko Sekimata; Kentaro Hatano; Mikako Ogawa; Junichiro Abe; Yasuhiro Magata; Giovanni Biggio; Mariangela Serra; Valentino Laquintana; Nunzio Denora; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso; Kengo Ito
Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors.
Mariangela Serra; Maria Giuseppina Pisu; Maria Cristina Mostallino; Enrico Sanna; Giovanni Biggio
Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function.
Carola Eva; Paolo Mele; Devis Collura; Antonella Nai; Maria Giuseppina Pisu; Mariangela Serra; Giovanni Biggio
Modulation of neuropeptide Y and Y1 receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y1R/LacZ transgenic mice.

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2008: Katsuhiko Sekimata; Kentaro Hatano; Mikako Ogawa; Junichiro Abe; Yasuhiro Magata; Giovanni Biggio; Mariangela Serra; Valentino Laquintana; Nunzio Denora; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso; Kengo Ito
Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors.
Nuclear medicine and biology 2008;35(3):327-34.
2008: Mariangela Serra; Maria Giuseppina Pisu; Maria Cristina Mostallino; Enrico Sanna; Giovanni Biggio
Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function.
Brain research reviews 2008;57(2):520-30.
2008: Carola Eva; Paolo Mele; Devis Collura; Antonella Nai; Maria Giuseppina Pisu; Mariangela Serra; Giovanni Biggio
Modulation of neuropeptide Y and Y1 receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y1R/LacZ transgenic mice.
Journal of neurochemistry 2008;104(4):1043-54.
2007: Giovanni Biggio; Alessandra Concas; Paolo Follesa; Enrico Sanna; Mariangela Serra
Stress, ethanol, and neuroactive steroids.
Pharmacology & therapeutics 2007;116(1):140-71.
2007: Valentino Laquintana; Nunzio Denora; Angela Lopedota; Hiromi Suzuki; Makoto Sawada; Mariangela Serra; Giovanni Biggio; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso
N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization.
Bioconjugate chemistry 2007;18(5):1397-407.
2007: Alessandra Falchi; Barbara Battetta; Fabrizio Sanna; Marco Piludu; Valeria Sogos; Mariangela Serra; Marta Melis; Marirosa Putzolu; Giacomo Diaz
Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands.
Neuropharmacology 2007;53(2):318-29.
2007: Nunzio Denora; Valentino Laquintana; Angela Lopedota; Mariangela Serra; Laura Dazzi; Giovanni Biggio; Dhananjay Pal; Laura jane Jolliffe; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso
Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.
Pharmaceutical research 2007;24(7):1309-24.
2007: Mariangela Serra; Enrico Sanna; Maria Cristina Mostallino; Giovanni Biggio
Social isolation stress and neuroactive steroids.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2007;17(1):1-11.
2006: Carola Eva; Mariangela Serra; Paolo Mele; GianCarlo Panzica; Alessandra Oberto
Physiology and gene regulation of the brain NPY Y1 receptor.
Frontiers in neuroendocrinology 2006;27(3):308-39.
2006: Maria Giuseppina Pisu; Ivan Floris; Elisabetta Maciocco; Mariangela Serra; Giovanni Biggio
Anticipation and consumption of food each increase the concentration of neuroactive steroids in rat brain and plasma.
Pharmacology, biochemistry, and behavior 2006;85(1):76-81.
2006: maria carolina hardoy; Mariangela Serra; Mauro Giovanni Carta; Paolo Contu; Maria Giuseppina Pisu; Giovanni Biggio
Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder.
Journal of clinical psychopharmacology 2006;26(4):379-84.
2006: Carola Eva; Alessandra Oberto; Paolo Mele; Mariangela Serra; Giovanni Biggio
Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala.
Pharmacology, biochemistry, and behavior 2006;84(4):568-80.
2006: Mariangela Serra; Maria Cristina Mostallino; Giuseppe Talani; Maria Giuseppina Pisu; Mario Carta; Maria Luisa Mura; Ivan Floris; Elisabetta Maciocco; Enrico Sanna; Giovanni Biggio
Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function.
Journal of neurochemistry 2006;98(1):122-33.
2006: Paolo Follesa; Francesca Biggio; Giuseppe Talani; Luca Murru; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Neurosteroids, GABAA receptors, and ethanol dependence.
Psychopharmacology 2006;186(3):267-80.
2005: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Giovanni Biggio
Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat.
Stress (Amsterdam, Netherlands) 2005;8(4):259-64.
2005: Enrico Sanna; Fabio Busonero; Giuseppe Talani; Maria Cristina Mostallino; Maria Luisa Mura; Maria Giuseppina Pisu; Elisabetta Maciocco; Mariangela Serra; Giovanni Biggio
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates.
European journal of pharmacology 2005;519(1-2):31-42.
2005: Giuseppe Trapani; Valentino Laquintana; Nunzio Denora; Adriana Trapani; Angela Lopedota; Andrea Latrofa; Massimo Franco; Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands.
Journal of medicinal chemistry 2005;48(1):292-305.
2004: Enrico Sanna; Giuseppe Talani; Fabio Busonero; Maria Giuseppina Pisu; Robert H Purdy; Mariangela Serra; Giovanni Biggio
Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6521-30.
2004: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Stefano Floris; Emanuela Cannas; Alessandra Mossa; Giuseppe Trapani; Andrea Latrofa; Robert H Purdy; Giovanni Biggio
Social isolation increases the response of peripheral benzodiazepine receptors in the rat.
Neurochemistry international 2004;45(1):141-8.
2004: Paolo Mele; Alessandra Oberto; Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Giovanni Biggio; Carola Eva
Increased expression of the gene for the Y1 receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y1R/LacZ transgenic mice in response to restraint stress.
Journal of neurochemistry 2004;89(6):1471-8.
2004: Carola Eva; Paolo Mele; Alessandra Oberto; GianCarlo Panzica; Maria Giuseppina Pisu; Mariangela Serra
Neuroanatomical and pharmacological evidence for a functional interaction between GABAergic and NPY-Y1 transmission in the amygdala of Y1R/LacZ transgenic mice.
Critical reviews in neurobiology 2004;16(1-2):33-41.
2004: Giuseppe Trapani; Annalisa Cutrignelli; Andrea Latrofa; Massimo Franco; Mariangela Serra; Maria Giuseppina Pisu; Giovanni Biggio; Gaetano Liso
Valproic acid-hydrophilic cyclodextrin complexes and valproic acid-solid dispersions: evaluation of their potential pharmaceutical use.
Drug development and industrial pharmacy 2004;30(1):53-64.
2003: Cosimo Altomare; Giuseppe Trapani; Andrea Latrofa; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(1):17-26.
2003: Giuseppe Trapani; Valentino Laquintana; Andrea Latrofa; Jianguo Ma; Karin Reed; Mariangela Serra; Giovanni Biggio; Gaetano Liso; James M Gallo
Peripheral benzodiazepine receptor ligand-melphalan conjugates for potential selective drug delivery to brain tumors.
Bioconjugate chemistry 2003;14(4):830-9.
2003: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Valeria Cara; Robert H Purdy; Giovanni Biggio
Social isolation-induced increase in the sensitivity of rats to the steroidogenic effect of ethanol.
Journal of neurochemistry 2003;85(1):257-63.
2003: Giuseppe Trapani; Andrea Latrofa; Massimo Franco; Antonio Carrieri; Saverio Cellamare; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(3-4):231-40.
2002: Laura Dazzi; Mariangela Serra; Emanuele Seu; Giulia Cherchi; Maria Giuseppina Pisu; Robert H Purdy; Giovanni Biggio
Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride.
Journal of neurochemistry 2002;83(5):1103-9.
2002: Alessandra Oberto; Mariangela Serra; Maria Giuseppina Pisu; Giovanni Biggio; Carola Eva
Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery.
Journal of neurochemistry 2002;82(5):1272-81.
2002: Mariangela Serra; M Giuseppina Pisul; Laura Dazzi; Robert H Purdy; Giovanni Biggio
Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine.
Journal of psychopharmacology (Oxford, England) 2002;16(2):133-8.
2002: Laura Dazzi; Mariangela Serra; Giovanni Vacca; Stefania Ladu; Andrea Latrofa; Giuseppe Trapani; Giovanni Biggio
Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output.
Brain research 2002;932(1-2):135-9.
2001: Maria Giuseppina Pisu; G Papi; Patrizia Porcu; Giuseppe Trapani; Andrea Latrofa; Giovanni Biggio; Mariangela Serra
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.
European journal of pharmacology 2001;432(2-3):129-34.
2001: Paolo Follesa; Alessandra Concas; Patrizia Porcu; Enrico Sanna; Mariangela Serra; Maria Cristina Mostallino; Robert H Purdy; Giovanni Biggio
Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone.
Brain research. Brain research reviews 2001;37(1-3):81-90.
2001: Mariangela Serra; Maria Giuseppina Pisu; M Muggironi; V Parodo; G Papi; R Sari; Laura Dazzi; Francesca Spiga; Robert H Purdy; Giovanni Biggio
Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain.
Psychopharmacology 2001;158(1):48-54.
2001: G Ferrara; Mariangela Serra; Francesca Zammaretti; Maria Giuseppina Pisu; GianCarlo Panzica; Giovanni Biggio; Carola Eva
Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone.
Journal of neurochemistry 2001;79(2):417-25.
2001: Laura Dazzi; Mariangela Serra; Francesca Spiga; Maria Giuseppina Pisu; J David Jentsch; Giovanni Biggio
Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2001;11(5):343-9.
2001: Massimo Franco; Giuseppe Trapani; Andrea Latrofa; C Tullio; M R Provenzano; Mariangela Serra; M Muggironi; Giovanni Biggio; Gaetano Liso
Dissolution properties and anticonvulsant activity of phenytoin-polyethylene glycol 6000 and -polyvinylpyrrolidone K-30 solid dispersions.
International journal of pharmaceutics 2001;225(1-2):63-73.
2001: Laura Dazzi; Giovanni Vacca; Stefania Ladu; Maria Giuseppina Pisu; Mariangela Serra; Giovanni Biggio
Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142.
Neuropharmacology 2001;41(2):229-37.
2001: Andrea Latrofa; Giuseppe Trapani; Massimo Franco; Mariangela Serra; M Muggironi; F P Fanizzi; Annalisa Cutrignelli; Gaetano Liso
Complexation of phenytoin with some hydrophilic cyclodextrins: effect on aqueous solubility, dissolution rate, and anticonvulsant activity in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2001;52(1):65-73.
2001: Luisa Savini; Luisa Chiasserini; Cesare Pellerano; Giovanni Biggio; Elisabetta Maciocco; Mariangela Serra; N Cinone; Antonio Carrieri; Cosimo Altomare; Angelo Carotti
High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure-activity relationships and comparative molecular field analysis of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 2001;9(2):431-44.
2001: Maria Luisa Barbaccia; Mariangela Serra; Robert H Purdy; Giovanni Biggio
Stress and neuroactive steroids.
International review of neurobiology 2001;46():243-72.
2000: Mariangela Serra; M Littera; Maria Giuseppina Pisu; M Muggironi; Robert H Purdy; Giovanni Biggio
Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine.
Neuropharmacology 2000;39(12):2448-56.
2000: Mariangela Serra; Maria Giuseppina Pisu; M Littera; G Papi; Enrico Sanna; Federica Tuveri; L Usala; Robert H Purdy; Giovanni Biggio
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Journal of neurochemistry 2000;75(2):732-40.
2000: Paolo Follesa; Mariangela Serra; E Cagetti; Maria Giuseppina Pisu; S Porta; Stefano Floris; Federico Massa; Enrico Sanna; Giovanni Biggio
Allopregnanolone synthesis in cerebellar granule cells: roles in regulation of GABA(A) receptor expression and function during progesterone treatment and withdrawal.
Molecular pharmacology 2000;57(6):1262-70.
2000: Alessandra Concas; Patrizia Porcu; Cristiana Sogliano; Mariangela Serra; Robert H Purdy; Giovanni Biggio
Caffeine-induced increases in the brain and plasma concentrations of neuroactive steroids in the rat.
Pharmacology, biochemistry, and behavior 2000;66(1):39-45.
1999: Giuseppe Trapani; Massimo Franco; Andrea Latrofa; L Ricciardi; A Carotti; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies.
Journal of medicinal chemistry 1999;42(19):3934-41.
1999: Mariangela Serra; Laura Dazzi; M Caddeo; Costantino Floris; Giovanni Biggio
Reversal by flunarizine of the decrease in hippocampal acetylcholine release in pentylenetetrazole-kindled rats.
Biochemical pharmacology 1999;58(1):145-9.
1999: Paolo Follesa; A Tarantino; Stefano Floris; A Mallei; S Porta; G Tuligi; E Cagetti; M Caddeo; A Mura; Mariangela Serra; Giovanni Biggio
Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling.
Brain research. Molecular brain research 1999;70(1):1-8.
1999: Mariangela Serra; P Madau; M F Chessa; M Caddeo; Enrico Sanna; Giuseppe Trapani; M Franco; Gaetano Liso; Robert H Purdy; Maria Luisa Barbaccia; Giovanni Biggio
2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.
British journal of pharmacology 1999;127(1):177-87.
1999: Mariangela Serra; Alessandra Concas; Maria Cristina Mostallino; M F Chessa; Massimo Stomati; Felice Petraglia; A R Genazzani; Giovanni Biggio
Antagonism by pivagabine of stress-induced changes in GABAA receptor function and corticotropin-releasing factor concentrations in rat brain.
Psychoneuroendocrinology 1999;24(3):269-84.
1999: Enrico Sanna; Costantino Motzo; M Usala; Mariangela Serra; Laura Dazzi; Elisabetta Maciocco; Giuseppe Trapani; Andrea Latrofa; Gaetano Liso; Giovanni Biggio
Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties.
British journal of pharmacology 1999;126(6):1444-54.
1998: Maria Luisa Barbaccia; Alessandra Concas; Mariangela Serra; Giovanni Biggio
Stress and neurosteroids in adult and aged rats.
Experimental gerontology 1998;33(7-8):697-712.
1997: Laura Dazzi; Mariangela Serra; M L Porceddu; A Sanna; M F Chessa; Giovanni Biggio
Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of freely moving rats by PTZ-induced kindling.
Synapse (New York, N.Y.) 1997;26(4):351-8.
1997: Mariangela Serra; R Cuccu; Carmen Ghiani; Maria Giuseppina Pisu; A Murgia; Giovanni Biggio
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam.
Neurochemical research 1997;22(6):693-7.
1997: Costantino Motzo; M L Porceddu; Laura Dazzi; A Sanna; Mariangela Serra; Giovanni Biggio
Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil.
Psychopharmacology 1997;131(1):34-9.
1997: Mariangela Serra; Laura Dazzi; Maria Giuseppina Pisu; E Cagetti; Giovanni Biggio
Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats.
Brain research 1997;751(1):175-9.
1997: Mariangela Serra; Laura Dazzi; E Cagetti; M F Chessa; Maria Giuseppina Pisu; A Sanna; Giovanni Biggio
Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats.
Journal of neurochemistry 1997;68(1):313-8.
1996: Giuseppe Trapani; Massimo Franco; Andrea Latrofa; Angelo Carotti; S Cellamare; Mariangela Serra; Carmen Ghiani; G Tuligi; Giovanni Biggio; Gaetano Liso
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents.
The Journal of pharmacy and pharmacology 1996;48(8):834-40.
1996: Carmen Ghiani; G Tuligi; Elisabetta Maciocco; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Biochemical pharmacology 1996;51(11):1527-34.
1996: Mariangela Serra; Carmen Ghiani; Elisabetta Maciocco; Maria Giuseppina Pisu; G Tuligi; M L Porceddu; G Giggio
Failure of chronic treatment with abecarnil to induce contigent and noncontingent tolerance in pentylenetetrazol-kindled rats.
Epilepsia 1996;37(4):332-5.
1995: Mariangela Serra; Carmen Ghiani; Costantino Motzo; M L Porceddu; Giovanni Biggio
Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam.
Pharmacology, biochemistry, and behavior 1995;52(2):249-54.
1995: Laura Dazzi; Costantino Motzo; G Maira; A Sanna; Mariangela Serra; Giovanni Biggio
Enhancement of acetylcholine release by flumazenil in the hippocampus of rats chronically treated with diazepam but not with imidazenil or abecarnil.
Psychopharmacology 1995;121(2):180-5.
1995: Laura Dazzi; Costantino Motzo; Assunta Imperato; Mariangela Serra; Gian Luigi Gessa; Giovanni Biggio
Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators.
The Journal of pharmacology and experimental therapeutics 1995;273(1):241-7.
1995: T Cuccheddu; Stefano Floris; Mariangela Serra; M L Porceddu; Enrico Sanna; Giovanni Biggio
Proconflict effect of carbon dioxide inhalation in rats.
Life sciences 1995;56(16):PL321-4.
1994: Mariangela Serra; Carmen Ghiani; S Spano; Giovanni Biggio
Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain.
European journal of pharmacology 1994;265(3):185-8.
1994: Alessandra Concas; Mariangela Serra; G Santoro; Elisabetta Maciocco; T Cuccheddu; Giovanni Biggio
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(3):294-300.
1994: Assunta Imperato; Laura Dazzi; Mariangela Serra; Gian Luigi Gessa; Giovanni Biggio
Differential effects of abecarnil on basal release of acetylcholine and dopamine in the rat brain.
European journal of pharmacology 1994;261(1-2):205-8.
1994: Mariangela Serra; Carmen Ghiani; Costantino Motzo; M L Porceddu; Giovanni Biggio
Long-term treatment with abecarnil fails to induce tolerance in mice.
European journal of pharmacology 1994;259(1):1-6.
1994: Mariangela Serra; Carmen Ghiani; Costantino Motzo; T Cuccheddu; Stefano Floris; P Giusti; Giovanni Biggio
Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.
The Journal of pharmacology and experimental therapeutics 1994;269(1):32-8.
1994: Mariangela Serra; Carmen Ghiani; M C Foddi; Costantino Motzo; Giovanni Biggio
NMDA receptor function is enhanced in the hippocampus of aged rats.
Neurochemical research 1994;19(4):483-7.
1994: Carmen Ghiani; Mariangela Serra; Costantino Motzo; P Giusti; T Cuccheddu; M L Porceddu; Giovanni Biggio
Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice.
European journal of pharmacology 1994;254(3):299-302.
1993: Enrico Sanna; Mariangela Serra; A Cossu; Giancarlo Colombo; Paolo Follesa; T Cuccheddu; Alessandra Concas; Giovanni Biggio
Chronic ethanol intoxication induces differential effects on GABAA and NMDA receptor function in the rat brain.
Alcoholism, clinical and experimental research 1993;17(1):115-23.
1993: Mariangela Serra; Carmen Ghiani; Costantino Motzo; Giovanni Biggio
Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.
Psychopharmacology series 1993;11():62-78.
1992: Mariangela Serra; M C Foddi; Carmen Ghiani; Maria Antonietta Melis; Costantino Motzo; Alessandra Concas; Enrico Sanna; Giovanni Biggio
Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1360-8.
1992: Enrico Sanna; T Cuccheddu; Mariangela Serra; Alessandra Concas; Giovanni Biggio
Carbon dioxide inhalation reduces the function of GABAA receptors in the rat brain.
European journal of pharmacology 1992;216(3):457-8.
1992: Giovanni Biggio; M Cibin; Marco Diana; Fabio Fadda; Santo Davide Ferrara; L Gallimberti; Gian Luigi Gessa; Giampaolo Mereu; Zvani L Rossetti; Mariangela Serra
Suppression of voluntary alcohol intake in rats and alcoholics by gamma-hydroxybutyric acid: a non-GABAergic mechanism.
Advances in biochemical psychopharmacology 1992;47():281-8.
1992: Enrico Sanna; Mariangela Serra; A Cossu; Giancarlo Colombo; Paolo Follesa; Giovanni Biggio
GABAA and NMDA receptor function during chronic administration of ethanol.
Advances in biochemical psychopharmacology 1992;47():317-24.
1992: Alessandra Concas; Mariangela Serra; Enrico Sanna; S Pepitoni; M P Mascia; Giovanni Biggio
Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs.
Epilepsy research. Supplement 1992;8():77-85.
1992: Alessandra Concas; G Santoro; M P Mascia; Mariangela Serra; Enrico Sanna; Giovanni Biggio
The action of the general anesthetic propofol on GABAA receptors.
Advances in biochemical psychopharmacology 1992;47():349-63.
1991: Alessandra Concas; G Santoro; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Brain research 1991;542(2):225-32.
1991: Enrico Sanna; Alessandra Concas; Mariangela Serra; G Santoro; Giovanni Biggio
Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel.
The Journal of pharmacology and experimental therapeutics 1991;256(3):922-8.
1991: Alessandra Concas; M P Mascia; Enrico Sanna; G Santoro; Mariangela Serra; Giovanni Biggio
"In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(3):296-300.
1991: Mariangela Serra; Enrico Sanna; Alessandra Concas; C Foddi; Giovanni Biggio
Foot-shock stress enhances the increase of [35S]TBPS binding in the rat cerebral cortex and the convulsions induced by isoniazid.
Neurochemical research 1991;16(1):17-22.
1991: Mariangela Serra; Enrico Sanna; C Foddi; Alessandra Concas; Giovanni Biggio
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex.
Psychopharmacology 1991;104(3):351-5.
1991: Giovanni Biggio; Enrico Sanna; Mariangela Serra; G P Serra; Alessandra Concas
"In vivo" inhibition of GABAergic transmission increases 35S-TBPS binding in the rat brain.
Advances in experimental medicine and biology 1991;287():391-404.
1990: Alessandra Concas; G Santoro; M P Mascia; Mariangela Serra; Enrico Sanna; Giovanni Biggio
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;55(6):2135-8.
1990: Enrico Sanna; Alessandra Concas; Mariangela Serra; Giovanni Biggio
Enhancement of GABA-dependent chloride channel by "in vivo" administration of ethanol.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():91-2.
1990: Alessandra Concas; Enrico Sanna; M P Mascia; Mariangela Serra; Giovanni Biggio
Diazepam enhances bicuculline-induced increase of t-[35S]butylbicyclophosphorothionate binding in unwashed membrane preparations from rat cerebral cortex.
Neuroscience letters 1990;112(1):87-91.
1990: Enrico Sanna; Alessandra Concas; Mariangela Serra; Giovanni Biggio
In vivo administration of ethanol enhances the function of the gamma-aminobutyric acid-dependent chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;54(2):696-8.
1990: Alessandra Concas; Enrico Sanna; Mariangela Serra; M P Mascia; V Santoro; Giovanni Biggio
"Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors.
Advances in biochemical psychopharmacology 1990;46():89-108.
1989: Enrico Sanna; Mariangela Serra; S Pepitoni; Giovanni Biggio
Dramatic increase in nigral t-[35S]butylbicyclophosphorothionate binding sites elicited by the degeneration of the striato-nigral GABAergic pathway: reversal by diazepam.
Brain research 1989;501(1):144-9.
1989: Mariangela Serra; Enrico Sanna; Giovanni Biggio
Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex.
European journal of pharmacology 1989;164(2):385-8.
1989: Giovanni Biggio; Alessandra Concas; Maria G Corda; Mariangela Serra
Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors.
European journal of pharmacology 1989;161(2-3):173-80.
1988: Alessandra Concas; Mariangela Serra; T Atsoggiu; Giovanni Biggio
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Journal of neurochemistry 1988;51(6):1868-76.
1988: Alessandra Concas; Mariangela Serra; Maria G Corda; Giovanni Biggio
Changes of 36Cl- flux and 35S-TBPS binding induced by stress and gabaergic drugs.
Advances in biochemical psychopharmacology 1988;45():227-46.
1988: Alessandra Concas; Mariangela Serra; T Atsoggiu
[Effect of stress on the function of chloride channels associated with the GABA receptor complex].
Annali dell'Istituto superiore di sanità 1988;24(4):551-4.