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Luis Serrano

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Phenomena

Occupations

Thermodynamics

Chemicals & Drugs

Procedures

Protein Engineering

Disorders

Protein Denaturation

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Co-Publications
Name
15
Blanco, Francisco
11
Lacroix, Emmanuel
11
Rousseau, Frederic
11
Schymkowitz, Joost
11
Stricher, Francois
10
Villegas, Virtudes
9
Avilés, Francesc
9
Beltrao, Pedro
8
Ramírez-Alvarado, M
7
Filimonov, Vladimir
7
Kiel, Christina
7
López de la Paz, Manuela
7
Mateo, Pedro
5
Martínez, Jose
5
Isalan, Mark

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Publications

TOP 3
Encinar J A; Fernandez-Ballester G; Sánchez I E; Hurtado-Gomez E; Stricher F; Beltrao P; Serrano L
ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.
Van der Sloot Almer M; Kiel Christina; Serrano Luis; Stricher Francois
Protein design in biological networks: from manipulating the input to modifying the output.
Vanhee Peter; Stricher Francois; Baeten Lies; Verschueren Erik; Lenaerts Tom; Serrano Luis; Rousseau Frederic; Schymkowitz Joost
Protein-peptide interactions adopt the same structural motifs as monomeric protein folds.

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All Publications

2009: Encinar J A; Fernandez-Ballester G; Sánchez I E; Hurtado-Gomez E; Stricher F; Beltrao P; Serrano L
ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.
Bioinformatics (Oxford, England) 2009;25(18):2418-24.
2009: Van der Sloot Almer M; Kiel Christina; Serrano Luis; Stricher Francois
Protein design in biological networks: from manipulating the input to modifying the output.
Protein engineering, design & selection : PEDS 2009;22(9):537-42.
2009: Vanhee Peter; Stricher Francois; Baeten Lies; Verschueren Erik; Lenaerts Tom; Serrano Luis; Rousseau Frederic; Schymkowitz Joost
Protein-peptide interactions adopt the same structural motifs as monomeric protein folds.
Structure (London, England : 1993) 2009;17(8):1128-36.
2009: Fernandez-Ballester Gregorio; Beltrao Pedro; Gonzalez Jose Manuel; Song Young-Hwa; Wilmanns Matthias; Valencia Alfonso; Serrano Luis
Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.
Journal of molecular biology 2009;388(4):902-16.
2008: Arroyo M; Serrano L; Ansotegui L; Rocandio A M
[Nutritional status and diet quality in a group of school dancers]
Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral 2008;23(6):619.
2008: Redondo Pilar; Prieto Jesús; Muñoz Inés G; Alibés Andreu; Stricher Francois; Serrano Luis; Cabaniols Jean-Pierre; Daboussi Fayza; Arnould Sylvain; Perez Christophe; Duchateau Philippe; Pâques Frédéric; Blanco Francisco J; Montoya Guillermo
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases.
Nature 2008;456(7218):107-11.
2008: Marcaida María José; Prieto Jesús; Redondo Pilar; Nadra Alejandro D; Alibés Andreu; Serrano Luis; Grizot Sylvestre; Duchateau Philippe; Pâques Frédéric; Blanco Francisco J; Montoya Guillermo
Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16888-93.
2008: Esteras-Chopo Alexandra; Morra Giulia; Moroni Elisabetta; Serrano Luis; Lopez de la Paz Manuela; Colombo Giorgio
A molecular dynamics study of the interaction of D-peptide amyloid inhibitors with their target sequence reveals a potential inhibitory pharmacophore conformation.
Journal of molecular biology 2008;383(1):266-80.
2008: Arroyo M; Ansotegui L; Pereira E; Lacerda F; Valador N; Serrano L; Rocandio A Ma
[Body composition assessment and body image perception in a group of University females of the Basque Country]
Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral 2008;23(4):366-72.
2008: Sánchez-Hidalgo Marina; Martínez-Bueno Manuel; Fernández-Escamilla Ana M; Valdivia Eva; Serrano Luis; Maqueda Mercedes
Effect of replacing glutamic residues upon the biological activity and stability of the circular enterocin AS-48.
The Journal of antimicrobial chemotherapy 2008;61(6):1256-65.
2008: Baeten Lies; Reumers Joke; Tur Vicente; Stricher François; Lenaerts Tom; Serrano Luis; Rousseau Frederic; Schymkowitz Joost
Reconstruction of protein backbones from the BriX collection of canonical protein fragments.
PLoS computational biology 2008;4(5):e1000083.
2008: Isalan Mark; Lemerle Caroline; Michalodimitrakis Konstantinos; Horn Carsten; Beltrao Pedro; Raineri Emanuele; Garriga-Canut Mireia; Serrano Luis
Evolvability and hierarchy in rewired bacterial gene networks.
Nature 2008;452(7189):840-5.
2008: Sánchez Ignacio E; Beltrao Pedro; Stricher Francois; Schymkowitz Joost; Ferkinghoff-Borg Jesper; Rousseau Frederic; Serrano Luis
Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.
PLoS computational biology 2008;4(4):e1000052.
2008: Esteras-Chopo Alexandra; Pastor M Teresa; Serrano Luis; López de la Paz Manuela
New strategy for the generation of specific D-peptide amyloid inhibitors.
Journal of molecular biology 2008;377(5):1372-81.
2008: Fajardo-Sanchez Emmanuel; Stricher François; Pâques Frédéric; Isalan Mark; Serrano Luis
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences.
Nucleic acids research 2008;36(7):2163-73.
2008: Tokuriki Nobuhiko; Stricher Francois; Serrano Luis; Tawfik Dan S
How protein stability and new functions trade off.
PLoS computational biology 2008;4(2):e1000002.
2008: Pastor M Teresa; Kümmerer Nico; Schubert Vanessa; Esteras-Chopo Alexandra; Dotti Carlos G; López de la Paz Manuela; Serrano Luis
Amyloid toxicity is independent of polypeptide sequence, length and chirality.
Journal of molecular biology 2008;375(3):695-707.
2008: Lenaerts Tom; Ferkinghoff-Borg Jesper; Stricher Francois; Serrano Luis; Schymkowitz Joost W H; Rousseau Frederic
Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure.
BMC structural biology 2008;8():43.
2008: Kiel Christina; Beltrao Pedro; Serrano Luis
Analyzing protein interaction networks using structural information.
Annual review of biochemistry 2008;77():415-41.
2008: Di Ventura Barbara; Funaya Charlotta; Antony Claude; Knop Michael; Serrano Luis
Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast.
PloS one 2008;3(1):e1507.
2007: Pey Angel L; Stricher Francois; Serrano Luis; Martinez Aurora
Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases.
American journal of human genetics 2007;81(5):1006-24.
2007: Kiel Christina; Foglierini Mathilde; Kuemmerer Nico; Beltrao Pedro; Serrano Luis
A genome-wide Ras-effector interaction network.
Journal of molecular biology 2007;370(5):1020-32.
2007: Beltrao Pedro; Kiel Christina; Serrano Luis
Structures in systems biology.
Current opinion in structural biology 2007;17(3):378-84.
2007: Tokuriki Nobuhiko; Stricher Francois; Schymkowitz Joost; Serrano Luis; Tawfik Dan S
The stability effects of protein mutations appear to be universally distributed.
Journal of molecular biology 2007;369(5):1318-32.
2007: Cerdà-Costa N; Esteras-Chopo A; Avilés F X; Serrano L; Villegas V
Early kinetics of amyloid fibril formation reveals conformational reorganisation of initial aggregates.
Journal of molecular biology 2007;366(4):1351-63.
2007: Beltrao Pedro; Serrano Luis
Specificity and evolvability in eukaryotic protein interaction networks.
PLoS computational biology 2007;3(2):e25.
2007: Pastor M Teresa; Esteras-Chopo Alexandra; Serrano Luis
Hacking the code of amyloid formation: the amyloid stretch hypothesis.
Prion 2007;1(1):9-14.
2006: Di Ventura Barbara; Lemerle Caroline; Michalodimitrakis Konstantinos; Serrano Luis
From in vivo to in silico biology and back.
Nature 2006;443(7111):527-33.
2006: Sánchez I E; Tejero J; Gómez-Moreno C; Medina M; Serrano L
Point mutations in protein globular domains: contributions from function, stability and misfolding.
Journal of molecular biology 2006;363(2):422-32.
2006: Fernández-Escamilla Ana M; Ventura Salvador; Serrano Luis; Jiménez M Angeles
Design and NMR conformational study of a beta-sheet peptide based on Betanova and WW domains.
Protein science : a publication of the Protein Society 2006;15(10):2278-89.
2006: Rousseau Frederic; Schymkowitz Joost; Serrano Luis
Protein aggregation and amyloidosis: confusion of the kinds?
Current opinion in structural biology 2006;16(1):118-26.
2006: Arnould Sylvain; Chames Patrick; Perez Christophe; Lacroix Emmanuel; Duclert Aymeric; Epinat Jean-Charles; Stricher François; Petit Anne-Sophie; Patin Amélie; Guillier Sophie; Rolland Sandra; Prieto Jesús; Blanco Francisco J; Bravo Jerónimo; Montoya Guillermo; Serrano Luis; Duchateau Philippe; Pâques Frédéric
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets.
Journal of molecular biology 2006;355(3):443-58.
2006: Kiel Christina; Serrano Luis
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes.
Journal of molecular biology 2006;355(4):821-44.
2006: Santori Maria Isabel; Gonzalez Cayetano; Serrano Luis; Isalan Mark
Localized transfection with magnetic beads coated with PCR products and other nucleic acids.
Nature protocols 2006;1(2):526-31.
2006: Dublanche Yann; Michalodimitrakis Konstantinos; Kümmerer Nico; Foglierini Mathilde; Serrano Luis
Noise in transcription negative feedback loops: simulation and experimental analysis.
Molecular systems biology 2006;2():41.
2005: Neduva Victor; Linding Rune; Su-Angrand Isabelle; Stark Alexander; de Masi Federico; Gibson Toby J; Lewis Joe; Serrano Luis; Russell Robert B
Systematic discovery of new recognition peptides mediating protein interaction networks.
PLoS biology 2005;3(12):e405.
2005: Esteras-Chopo Alexandra; Serrano Luis; López de la Paz Manuela
The amyloid stretch hypothesis: recruiting proteins toward the dark side.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16672-7.
2005: Beltrao Pedro; Serrano Luis
Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions.
PLoS computational biology 2005;1(3):e26.
2005: Schymkowitz Joost W H; Rousseau Frederic; Martins Ivo C; Ferkinghoff-Borg Jesper; Stricher Francois; Serrano Luis
Prediction of water and metal binding sites and their affinities by using the Fold-X force field.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10147-52.
2005: Schymkowitz Joost; Borg Jesper; Stricher Francois; Nys Robby; Rousseau Frederic; Serrano Luis
The FoldX web server: an online force field.
Nucleic acids research 2005;33(Web Server issue):W382-8.
2005: López de la Paz Manuela; de Mori Giacomo M S; Serrano Luis; Colombo Giorgio
Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations.
Journal of molecular biology 2005;349(3):583-96.
2005: Bork Peer; Serrano Luis
Towards cellular systems in 4D.
Cell 2005;121(4):507-9.
2005: Kiel Christina; Wohlgemuth Sabine; Rousseau Frederic; Schymkowitz Joost; Ferkinghoff-Borg Jesper; Wittinghofer Fred; Serrano Luis
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations.
Journal of molecular biology 2005;348(3):759-75.
2005: Wohlgemuth Sabine; Kiel Christina; Krämer Astrid; Serrano Luis; Wittinghofer Fred; Herrmann Christian
Recognizing and defining true Ras binding domains I: biochemical analysis.
Journal of molecular biology 2005;348(3):741-58.
2005: Lemerle Caroline; Di Ventura Barbara; Serrano Luis
Space as the final frontier in stochastic simulations of biological systems.
FEBS letters 2005;579(8):1789-94.
2005: Isalan Mark; Lemerle Caroline; Serrano Luis
Engineering gene networks to emulate Drosophila embryonic pattern formation.
PLoS biology 2005;3(3):e64.
2005: Isalan Mark; Santori Maria Isabel; Gonzalez Cayetano; Serrano Luis
Localized transfection on arrays of magnetic beads coated with PCR products.
Nature methods 2005;2(2):113-8.
2005: Reumers Joke; Schymkowitz Joost; Ferkinghoff-Borg Jesper; Stricher Francois; Serrano Luis; Rousseau Frederic
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs.
Nucleic acids research 2005;33(Database issue):D527-32.
2004: Cobos Eva S; Pisabarro M Teresa; Vega M Cristina; Lacroix Emmanuel; Serrano Luis; Ruiz-Sanz Javier; Martinez Jose C
A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains.
Journal of molecular biology 2004;342(1):355-65.
2004: Linding Rune; Schymkowitz Joost; Rousseau Frederic; Diella Francesca; Serrano Luis
A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins.
Journal of molecular biology 2004;342(1):345-53.
2004: Kiel Christina; Serrano Luis; Herrmann Christian
A detailed thermodynamic analysis of ras/effector complex interfaces.
Journal of molecular biology 2004;340(5):1039-58.
2004: Ventura Salvador; Serrano Luis
Designing proteins from the inside out.
Proteins 2004;56(1):1-10.
2004: Ander M; Beltrao P; Di Ventura B; Ferkinghoff-Borg J; Foglierini M; Kaplan A; Lemerle C; Tomás-Oliveira I; Serrano L
SmartCell, a framework to simulate cellular processes that combines stochastic approximation with diffusion and localisation: analysis of simple networks.
Systems biology 2004;1(1):129-38.
2004: Ventura Salvador; Zurdo Jesús; Narayanan Saravanakumar; Parreño Matilde; Mangues Ramón; Reif Bernd; Chiti Fabrizio; Giannoni Elisa; Dobson Christopher M; Aviles Francesc X; Serrano Luis
Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7258-63.
2004: Aloy Patrick; Böttcher Bettina; Ceulemans Hugo; Leutwein Christina; Mellwig Christian; Fischer Susanne; Gavin Anne-Claude; Bork Peer; Superti-Furga Giulio; Serrano Luis; Russell Robert B
Structure-based assembly of protein complexes in yeast.
Science (New York, N.Y.) 2004;303(5666):2026-9.
2004: Fernández-Escamilla A M; Cheung M S; Vega M C; Wilmanns M; Onuchic J N; Serrano L
Solvation in protein folding analysis: combination of theoretical and experimental approaches.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2834-9.
2004: López de la Paz Manuela; Serrano Luis
Sequence determinants of amyloid fibril formation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):87-92.
2003: Villanueva Josep; Villegas Virtudes; Querol Enrique; Avilés Francesc X; Serrano Luis
Monitoring disappearance of monomers and generation of resistance to proteolysis during the formation of the activation domain of human procarboxypeptidase A2 (ADA2h) amyloid fibrils by matrix-assisted laser-desorption ionization-time-of-flight-MS.
The Biochemical journal 2003;374(Pt 2):489-95.
2003: Villanueva Josep; Yanes Oscar; Querol Enrique; Serrano Luis; Aviles Francesc X
Identification of protein ligands in complex biological samples using intensity-fading MALDI-TOF mass spectrometry.
Analytical chemistry 2003;75(14):3385-95.
2003: Villanueva Josep; Fernández-Ballester Gregorio; Querol Enrique; Aviles Francesc X; Serrano Luis
Ligand screening by exoproteolysis and mass spectrometry in combination with computer modelling.
Journal of molecular biology 2003;330(5):1039-48.
2003: Spagnolo Laura; Ventura Salvador; Serrano Luis
Folding specificity induced by loop stiffness.
Protein science : a publication of the Protein Society 2003;12(7):1473-82.
2003: Viguera Ana-Rosa; Serrano Luis
Hydrogen-exchange stability analysis of Bergerac-Src homology 3 variants allows the characterization of a folding intermediate in equilibrium.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5730-5.
2003: Cobos Eva S; Filimonov Vladimir V; Vega Maria Cristina; Mateo Pedro L; Serrano Luis; Martínez Jose C
A thermodynamic and kinetic analysis of the folding pathway of an SH3 domain entropically stabilised by a redesigned hydrophobic core.
Journal of molecular biology 2003;328(1):221-33.
2003: Jiménez M Angeles; Villegas Virtudes; Santoro Jorge; Serrano Luis; Vendrell Josep; Avilés Francesc X; Rico Manuel
NMR solution structure of the activation domain of human procarboxypeptidase A2.
Protein science : a publication of the Protein Society 2003;12(2):296-305.
2002: Schymkowitz Joost W H; Rousseau Frederic; Serrano Luis
Surfing on protein folding energy landscapes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):15846-8.
2002: López De La Paz Manuela; Goldie Kenneth; Zurdo Jesús; Lacroix Emmanuel; Dobson Christopher M; Hoenger Andreas; Serrano Luis
De novo designed peptide-based amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16052-7.
2002: Ventura Salvador; Lacroix Emmanuel; Serrano Luis
Insights into the origin of the tendency of the PI3-SH3 domain to form amyloid fibrils.
Journal of molecular biology 2002;322(5):1147-58.
2002: Villanueva Josep; Villegas Virtudes; Querol Enrique; Avilés Francesc X; Serrano Luis
Protein secondary structure and stability determined by combining exoproteolysis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Journal of mass spectrometry : JMS 2002;37(9):974-84.
2002: Mendes Joaquim; Guerois Raphael; Serrano Luis
Energy estimation in protein design.
Current opinion in structural biology 2002;12(4):441-6.
2002: Guerois Raphael; Nielsen Jens Erik; Serrano Luis
Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations.
Journal of molecular biology 2002;320(2):369-87.
2002: Ventura Salvador; Vega Maria Cristina; Lacroix Emmanuel; Angrand Isabelle; Spagnolo Laura; Serrano Luis
Conformational strain in the hydrophobic core and its implications for protein folding and design.
Nature structural biology 2002;9(6):485-93.
2002: Viguera Ana Rosa; Vega Cristina; Serrano Luis
Unspecific hydrophobic stabilization of folding transition states.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5349-54.
2002: Petukhov Michael; Uegaki Koichi; Yumoto Noboru; Serrano Luis
Amino acid intrinsic alpha-helical propensities III: positional dependence at several positions of C terminus.
Protein science : a publication of the Protein Society 2002;11(4):766-77.
2002: Pastor Maria Teresa; López de la Paz Manuela; Lacroix Emmanuel; Serrano Luis; Pérez-Payá Enrique
Combinatorial approaches: a new tool to search for highly structured beta-hairpin peptides.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):614-9.
2001: Angrand I; Serrano L; Lacroix E
Computer-assisted re-design of spectrin SH3 residue clusters.
Biomolecular engineering 2001;18(3):125-34.
2001: López de la Paz M; Lacroix E; Ramírez-Alvarado M; Serrano L
Computer-aided design of beta-sheet peptides.
Journal of molecular biology 2001;312(1):229-46.
2001: Ramírez-Alvarado M; Blanco F J; Serrano L
Elongation of the BH8 beta-hairpin peptide: Electrostatic interactions in beta-hairpin formation and stability.
Protein science : a publication of the Protein Society 2001;10(7):1381-92.
2001: Fisinger S; Serrano L; Lacroix E
Computational estimation of specific side chain interaction energies in alpha helices.
Protein science : a publication of the Protein Society 2001;10(4):809-18.
2001: Guerois R; Serrano L
Protein design based on folding models.
Current opinion in structural biology 2001;11(1):101-6.
2001: Berisio R; Viguera A; Serrano L; Wilmanns M
Atomic resolution structure of a mutant of the spectrin SH3 domain.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 2):337-40.
2000: Vega M C; Martínez J C; Serrano L
Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot.
Protein science : a publication of the Protein Society 2000;9(12):2322-8.
2000: Westerholm-Parvinen A; Vernos I; Serrano L
Kinesin subfamily UNC104 contains a FHA domain: boundaries and physicochemical characterization.
FEBS letters 2000;486(3):285-90.
2000: Solà M; López-Hernández E; Cronet P; Lacroix E; Serrano L; Coll M; Párraga A
Towards understanding a molecular switch mechanism: thermodynamic and crystallographic studies of the signal transduction protein CheY.
Journal of molecular biology 2000;303(2):213-25.
2000: Fernández A M; Villegas V; Martínez J C; Van Nuland N A; Conejero-Lara F; Avilés F X; Serrano L; Filimonov V V; Mateo P L
Thermodynamic analysis of helix-engineered forms of the activation domain of human procarboxypeptidase A2.
European journal of biochemistry / FEBS 2000;267(19):5891-9.
2000: Villegas V; Zurdo J; Filimonov V V; Avilés F X; Dobson C M; Serrano L
Protein engineering as a strategy to avoid formation of amyloid fibrils.
Protein science : a publication of the Protein Society 2000;9(9):1700-8.
2000: Kortemme T; Kelly M J; Kay L E; Forman-Kay J; Serrano L
Similarities between the spectrin SH3 domain denatured state and its folding transition state.
Journal of molecular biology 2000;297(5):1217-29.
1999: Martínez J C; Serrano L
The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved.
Nature structural biology 1999;6(11):1010-6.
1999: Petukhov M; Uegaki K; Yumoto N; Yoshikawa S; Serrano L
Position dependence of amino acid intrinsic helical propensities II: non-charged polar residues: Ser, Thr, Asn, and Gln.
Protein science : a publication of the Protein Society 1999;8(10):2144-50.
1999: Petukhov M; Cregut D; Soares C M; Serrano L
Local water bridges and protein conformational stability.
Protein science : a publication of the Protein Society 1999;8(10):1982-9.
1999: Cregut D; Civera C; Macias M J; Wallon G; Serrano L
A tale of two secondary structure elements: when a beta-hairpin becomes an alpha-helix.
Journal of molecular biology 1999;292(2):389-401.
1999: Viguera A R; Serrano L
Stable proline box motif at the N-terminal end of alpha-helices.
Protein science : a publication of the Protein Society 1999;8(9):1733-42.
1999: Lacroix E; Kortemme T; Lopez de la Paz M; Serrano L
The design of linear peptides that fold as monomeric beta-sheet structures.
Current opinion in structural biology 1999;9(4):487-93.
1999: Domingues H; Cregut D; Sebald W; Oschkinat H; Serrano L
Rational design of a GCN4-derived mimetic of interleukin-4.
Nature structural biology 1999;6(7):652-6.
1999: Filimonov V V; Azuaga A I; Viguera A R; Serrano L; Mateo P L
A thermodynamic analysis of a family of small globular proteins: SH3 domains.
Biophysical chemistry 1999;77(2-3):195-208.
1999: Cregut D; Serrano L
Molecular dynamics as a tool to detect protein foldability. A mutant of domain B1 of protein G with non-native secondary structure propensities.
Protein science : a publication of the Protein Society 1999;8(2):271-82.
1999: Ramírez-Alvarado M; Kortemme T; Blanco F J; Serrano L
Beta-hairpin and beta-sheet formation in designed linear peptides.
Bioorganic & medicinal chemistry 1999;7(1):93-103.
1999: Martínez J C; Viguera A R; Berisio R; Wilmanns M; Mateo P L; Filimonov V V; Serrano L
Thermodynamic analysis of alpha-spectrin SH3 and two of its circular permutants with different loop lengths: discerning the reasons for rapid folding in proteins.
Biochemistry 1999;38(2):549-59.
1999: Blanco F J; Angrand I; Serrano L
Exploring the conformational properties of the sequence space between two proteins with different folds: an experimental study.
Journal of molecular biology 1999;285(2):741-53.
1998: Lacroix E; Viguera A R; Serrano L
Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters.
Journal of molecular biology 1998;284(1):173-91.
1998: Villegas V; Martínez J C; Avilés F X; Serrano L
Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain.
Journal of molecular biology 1998;283(5):1027-36.
1998: Martinez J C; Pisabarro M T; Serrano L
Obligatory steps in protein folding and the conformational diversity of the transition state.
Nature structural biology 1998;5(8):721-9.
1998: Kortemme T; Ramírez-Alvarado M; Serrano L
Design of a 20-amino acid, three-stranded beta-sheet protein.
Science (New York, N.Y.) 1998;281(5374):253-6.
1998: Petukhov M; Muñoz V; Yumoto N; Yoshikawa S; Serrano L
Position dependence of non-polar amino acid intrinsic helical propensities.
Journal of molecular biology 1998;278(1):279-89.
1998: Blanco F; Ramírez-Alvarado M; Serrano L
Formation and stability of beta-hairpin structures in polypeptides.
Current opinion in structural biology 1998;8(1):107-11.
1998: Lacroix E; Viguera A R; Serrano L
Reading protein sequences backwards.
Folding & design 1998;3(2):79-85.
1997: Ramírez-Alvarado M; Blanco F J; Niemann H; Serrano L
Role of beta-turn residues in beta-hairpin formation and stability in designed peptides.
Journal of molecular biology 1997;273(4):898-912.
1997: Viguera A R; Serrano L
Loop length, intramolecular diffusion and protein folding.
Nature structural biology 1997;4(11):939-46.
1997: Lacroix E; Bruix M; López-Hernández E; Serrano L; Rico M
Amide hydrogen exchange and internal dynamics in the chemotactic protein CheY from Escherichia coli.
Journal of molecular biology 1997;271(3):472-87.
1997: Blanco F J; Ortiz A R; Serrano L
1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure.
Journal of biomolecular NMR 1997;9(4):347-57.
1997: Prieto J; Wilmans M; Jiménez M A; Rico M; Serrano L
Non-native local interactions in protein folding and stability: introducing a helical tendency in the all beta-sheet alpha-spectrin SH3 domain.
Journal of molecular biology 1997;268(4):760-78.
1997: López-Hernández E; Cronet P; Serrano L; Muñoz V
Folding kinetics of Che Y mutants with enhanced native alpha-helix propensities.
Journal of molecular biology 1997;266(3):610-20.
1997: Ramírez-Alvarado M; Serrano L; Blanco F J
Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: secondary structure propensities are not conserved in proteins with the same fold.
Protein science : a publication of the Protein Society 1997;6(1):162-74.
1997: Blanco F J; Ortiz A R; Serrano L
Role of a nonnative interaction in the folding of the protein G B1 domain as inferred from the conformational analysis of the alpha-helix fragment.
Folding & design 1997;2(2):123-33.
1997: Viguera A R; Villegas V; Avilés F X; Serrano L
Favourable native-like helical local interactions can accelerate protein folding.
Folding & design 1997;2(1):23-33.
1996: Viguera A R; Serrano L; Wilmanns M
Different folding transition states may result in the same native structure.
Nature structural biology 1996;3(10):874-80.
1996: Pisabarro M T; Serrano L
Rational design of specific high-affinity peptide ligands for the Abl-SH3 domain.
Biochemistry 1996;35(33):10634-40.
1996: Ramírez-Alvarado M; Blanco F J; Serrano L
De novo design and structural analysis of a model beta-hairpin peptide system.
Nature structural biology 1996;3(7):604-12.
1996: Bellsolell L; Cronet P; Majolero M; Serrano L; Coll M
The three-dimensional structure of two mutants of the signal transduction protein CheY suggest its molecular activation mechanism.
Journal of molecular biology 1996;257(1):116-28.
1996: Viguera A R; Jiménez M A; Rico M; Serrano L
Conformational analysis of peptides corresponding to beta-hairpins and a beta-sheet that represent the entire sequence of the alpha-spectrin SH3 domain.
Journal of molecular biology 1996;255(3):507-21.
1996: Muñoz V; Serrano L
Local versus nonlocal interactions in protein folding and stability--an experimentalist's point of view.
Folding & design 1996;1(4):R71-7.
1996: Muñoz V; Cronet P; López-Hernández E; Serrano L
Analysis of the effect of local interactions on protein stability.
Folding & design 1996;1(3):167-78.
1996: López-Hernández E; Serrano L
Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2.
Folding & design 1996;1(1):43-55.
1996: Villegas V; Viguera A R; Avilés F X; Serrano L
Stabilization of proteins by rational design of alpha-helix stability using helix/coil transition theory.
Folding & design 1996;1(1):29-34.
1995: Muñoz V; Serrano L
Analysis of i,i+5 and i,i+8 hydrophobic interactions in a helical model peptide bearing the hydrophobic staple motif.
Biochemistry 1995;34(46):15301-6.
1995: Villegas V; Azuaga A; Catasús L; Reverter D; Mateo P L; Avilés F X; Serrano L
Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2.
Biochemistry 1995;34(46):15105-10.
1995: Muñoz V; Blanco F J; Serrano L
The distribution of alpha-helix propensity along the polypeptide chain is not conserved in proteins from the same family.
Protein science : a publication of the Protein Society 1995;4(8):1577-86.
1995: Viguera A R; Serrano L
Experimental analysis of the Schellman motif.
Journal of molecular biology 1995;251(1):150-60.
1995: López-Hernández E; Serrano L
Empirical correlation for the replacement of Ala by Gly: importance of amino acid secondary intrinsic propensities.
Proteins 1995;22(4):340-9.
1995: Viguera A R; Serrano L
Side-chain interactions between sulfur-containing amino acids and phenylalanine in alpha-helices.
Biochemistry 1995;34(27):8771-9.
1995: Cronet P; Bellsolell L; Sander C; Coll M; Serrano L
Investigating the structural determinants of the p21-like triphosphate and Mg2+ binding site.
Journal of molecular biology 1995;249(3):654-64.
1995: Muñoz V; Blanco F J; Serrano L
The hydrophobic-staple motif and a role for loop-residues in alpha-helix stability and protein folding.
Nature structural biology 1995;2(5):380-5.
1995: Viguera A R; Blanco F J; Serrano L
The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
Journal of molecular biology 1995;247(4):670-81.
1995: Muñoz V; Serrano L; Jiménez M A; Rico M
Structural analysis of peptides encompassing all alpha-helices of three alpha/beta parallel proteins: Che-Y, flavodoxin and P21-ras: implications for alpha-helix stability and the folding of alpha/beta parallel proteins.
Journal of molecular biology 1995;247(4):648-69.
1995: Muñoz V; Serrano L
Elucidating the folding problem of helical peptides using empirical parameters. III. Temperature and pH dependence.
Journal of molecular biology 1995;245(3):297-308.
1995: Muñoz V; Serrano L
Elucidating the folding problem of helical peptides using empirical parameters. II. Helix macrodipole effects and rational modification of the helical content of natural peptides.
Journal of molecular biology 1995;245(3):275-96.
1994: Muñoz V; Serrano L
Intrinsic secondary structure propensities of the amino acids, using statistical phi-psi matrices: comparison with experimental scales.
Proteins 1994;20(4):301-11.
1994: Pisabarro M T; Ortiz A R; Viguera A R; Gago F; Serrano L
Molecular modeling of the interaction of polyproline-based peptides with the Abl-SH3 domain: rational modification of the interaction.
Protein engineering 1994;7(12):1455-62.
1994: Pisabarro M T; Ortiz A R; Serrano L; Wade R C
Homology modeling of the Abl-SH3 domain.
Proteins 1994;20(3):203-15.
1994: Viguera A R; Arrondo J L; Musacchio A; Saraste M; Serrano L
Characterization of the interaction of natural proline-rich peptides with five different SH3 domains.
Biochemistry 1994;33(36):10925-33.
1994: Jiménez M A; Muñoz V; Rico M; Serrano L
Helix stop and start signals in peptides and proteins. The capping box does not necessarily prevent helix elongation.
Journal of molecular biology 1994;242(4):487-96.
1994: Blanco F J; Rivas G; Serrano L
A short linear peptide that folds into a native stable beta-hairpin in aqueous solution.
Nature structural biology 1994;1(9):584-90.
1994: Muñoz V; Serrano L
Elucidating the folding problem of helical peptides using empirical parameters.
Nature structural biology 1994;1(6):399-409.
1994: Muñoz V; Lopez E M; Jager M; Serrano L
Kinetic characterization of the chemotactic protein from Escherichia coli, CheY. Kinetic analysis of the inverse hydrophobic effect.
Biochemistry 1994;33(19):5858-66.
1994: Bellsolell L; Prieto J; Serrano L; Coll M
Magnesium binding to the bacterial chemotaxis protein CheY results in large conformational changes involving its functional surface.
Journal of molecular biology 1994;238(4):489-95.
1994: Viguera A R; Martínez J C; Filimonov V V; Mateo P L; Serrano L
Thermodynamic and kinetic analysis of the SH3 domain of spectrin shows a two-state folding transition.
Biochemistry 1994;33(8):2142-50.
1993: Filimonov V V; Prieto J; Martinez J C; Bruix M; Mateo P L; Serrano L
Thermodynamic analysis of the chemotactic protein from Escherichia coli, CheY.
Biochemistry 1993;32(47):12906-21.

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