FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

William Sessa

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Physiology

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Irina M Jaba; Yifeng Jiang; Na Li; Kathleen A Martin; Xenophon Papademetris; William C Sessa; Michael Simons; Albert J Sinusas; Lawrence H Young; Zhen W Zhuang; Daniela Tirziu
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth.
Shira Landskroner-Eiger; Isabelle Moneke; William C Sessa
miRNAs as modulators of angiogenesis.
Won-Kyung Cho; Jack A Elias; Frank J Giordano; Robert J Homer; Yan Huang; Min-Jong Kang; Chang-Min Lee; Patty J Lee; William C Sessa; Terence K Trow; Chun Geun Lee
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of William Sessa (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Irina M Jaba; Yifeng Jiang; Na Li; Kathleen A Martin; Xenophon Papademetris; William C Sessa; Michael Simons; Albert J Sinusas; Lawrence H Young; Zhen W Zhuang; Daniela Tirziu
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth.
The Journal of clinical investigation 2013;123(4):1718-31.
2013: Shira Landskroner-Eiger; Isabelle Moneke; William C Sessa
miRNAs as modulators of angiogenesis.
Cold Spring Harbor perspectives in medicine 2013;3(2):a006643.
2013: Won-Kyung Cho; Jack A Elias; Frank J Giordano; Robert J Homer; Yan Huang; Min-Jong Kang; Chang-Min Lee; Patty J Lee; William C Sessa; Terence K Trow; Chun Geun Lee
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2013;304(2):L112-24.
2013: Julie E Goodwin; Yan Feng; Heino Velazquez; William C Sessa
Endothelial glucocorticoid receptor is required for protection against sepsis.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(1):306-11.
2012: Pei Zhang; Angela Huang; Yan Huang; Manuel Morales-Ruiz; Laura E Niklason; William C Sessa; Barry C Starcher; Frank J Giordano
Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis.
Human gene therapy 2012;23(11):1186-99.
2012: Ethan P Marin; Alberto Davalos; Behrad Derakhshan; Tukiet T Lam; William C Sessa
Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases.
Circulation research 2012;110(10):1336-44.
2012: Jiange Zhang; Yizhun Zhu; Mark Collinge; Themis Kyriakides; Yasha Modi; Ruggero Pardi; William C Sessa; Timur Yarovinsky; Jun Yu; Jeffrey R Bender
Macrophage β2 integrin-mediated, HuR-dependent stabilization of angiogenic factor-encoding mRNAs in inflammatory angiogenesis.
The American journal of pathology 2012;180(4):1751-60.
2012: Pei Zhang; Barry C Starcher; George Tellides; Jacopo Ferruzzi; Frank J Giordano; Angela Huang; Jay D Humphrey; Robert P Mecham; Laura E Niklason; William C Sessa
Inhibition of microRNA-29 enhances elastin levels in cells haploinsufficient for elastin and in bioengineered vessels--brief report.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(3):756-9.
2012: Tai Yi; Deepak A Rao; William C Sessa; George Tellides; Zuzana Tobiasova; Chen Wang; Rafia S Al-Lamki; Alfred L M Bothwell; John R Bradley; Birgit Fogal; Zhengrong Hao; Nancy C Kirkiles-Smith; Sanjay Kulkarni; Jordan S Pober
Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(2):353-60.
2012: Panjamaporn Sangwung; William C Sessa; Yanzhuang Wang; Todd M Greco; Harry Ischiropoulos; Yasuko Iwakiri
Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO.
PloS one 2012;7(2):e31564.
2012: Jun Yu; Xinbo Zhang; Yuanyuan Zhang; Dario C Altieri; Philip M Bauer; Radu Daniel Rudic; William C Sessa
Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling.
PloS one 2012;7(2):e31495.
2011: Susan MacLauchlan; Marcus Parrish; Michael Schleicher; William C Sessa; Jun Yu; Jianmin Zeng; Tara A Asoulin; Paul L Huang; Marie M Krady; Themis R Kyriakides
Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):E1137-45.
2011: William C Sessa
MicroRNA regulation of cardiovascular functions.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(11):2369.
2011: Pascal N Bernatchez; Ethan Marin; Philip M Bauer; Arpeeta Sharma; William C Sessa
A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice.
The Journal of clinical investigation 2011;121(9):3747-55.
2011: Kenneth D Harrison; Andrew Kuo; Mark A Lehrman; Eon Joo Park; Jeffrey S Rush; Ningguo Gao; Charles J Waechter; William C Sessa
Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation.
The EMBO journal 2011;30(12):2490-500.
2011: Sebastian Albinsson; William C Sessa
Can microRNAs control vascular smooth muscle phenotypic modulation and the response to injury?
Physiological genomics 2011;43(10):529-33.
2011: Dahai Zhang; Teruo Utsumi; Hui-Chun Huang; Lili Gao; Panjamaporn Sangwung; Chuhan Chung; Kazunori Shibao; Kohji Okamoto; Koji Yamaguchi; Roberto J Groszmann; Levente Jozsef; Zhengrong Hao; William C Sessa; Yasuko Iwakiri
Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis.
Hepatology (Baltimore, Md.) 2011;53(4):1306-15.
2011: Akihito Muto; Tai Yi; Kenneth D Harrison; Alberto Dávalos; Tiffany T Fancher; Kenneth R Ziegler; Amanda Feigel; Yuka Kondo; Toshiya Nishibe; William C Sessa; Alan Dardik
Eph-B4 prevents venous adaptive remodeling in the adult arterial environment.
The Journal of experimental medicine 2011;208(3):561-75.
2011: Sebastian Albinsson; Athanasia Skoura; Jun Yu; Annarita DiLorenzo; Carlos Fernández-Hernando; Stefan Offermanns; Joseph M Miano; William C Sessa
Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function.
PloS one 2011;6(4):e18869.
2010: Ethan P Marin; Gilbert W Moeckel; Rafia S Al-Lamki; John Bradley; Qingshang Yan; Tong Wang; Paulette L Wright; Jun Yu; William C Sessa
Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells.
The American journal of pathology 2010;177(6):2765-73.
2010: Paulette L Wright; Jun Yu; Y P Peter Di; Robert J Homer; Geoffrey L Chupp; Jack A Elias; Lauren Cohn; William C Sessa
Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.
The Journal of experimental medicine 2010;207(12):2595-607.
2010: Naoki Terasaka; Marit Westerterp; Joris Koetsveld; Carlos Fernández-Hernando; Laurent Yvan-Charvet; Nan Wang; William C Sessa; Alan R Tall
ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(11):2219-25.
2010: Alberto Dávalos; Carlos Fernández-Hernando; Grzegorz Sowa; Derakhshan Behrad; Michelle I Lin; Ji Y Lee; Hongyu Zhao; Ruiyan Luo; Christopher M Colangelo; William C Sessa
Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells.
Molecular & cellular proteomics : MCP 2010;9(10):2109-24.
2010: Adam S Lazorchak; Dou Liu; Valeria Facchinetti; Annarita Di Lorenzo; William C Sessa; David G Schatz; Bing Su
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.
Molecular cell 2010;39(3):433-43.
2010: William C Sessa
A new way to lower blood pressure: pass the chili peppers please!
Cell metabolism 2010;12(2):109-10.
2010: Carlos Fernández-Hernando; Jun Yu; Alberto Dávalos; Jay Prendergast; William C Sessa
Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice.
The American journal of pathology 2010;177(2):998-1003.
2010: Sebastian Albinsson; Yajaira Suarez; Athanasia Skoura; Stefan Offermanns; Joseph M Miano; William C Sessa
MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(6):1118-26.
2010: John H Chidlow; William C Sessa
Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation.
Cardiovascular research 2010;86(2):219-25.
2009: Carlos Fernández-Hernando; Levente József; Deborah Jenkins; Annarita Di Lorenzo; William C Sessa
Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(12):2033-40.
2009: Jun Yu; Carlos Fernández-Hernando; Yajaira Suarez; Michael Schleicher; Zhengrong Hao; Paulette L Wright; Annarita DiLorenzo; Themis R Kyriakides; William C Sessa
Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17511-6.
2009: Kenneth D Harrison; Robert Qing Miao; Carlos Fernandez-Hernándo; Yajaira Suárez; Alberto Dávalos; William C Sessa
Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking.
Cell metabolism 2009;10(3):208-18.
2009: Pascal N Bernatchez; Arpeeta Sharma; Pinar Kodaman; William C Sessa
Myoferlin is critical for endocytosis in endothelial cells.
American journal of physiology. Cell physiology 2009;297(3):C484-92.
2009: Annarita Di Lorenzo; Carlos Fernández-Hernando; Giuseppe Cirino; William C Sessa
Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14552-7.
2009: Lawrence W Dobrucki; Donald P Dione; Leszek Kalinowski; Donald P Dione; Marivi Mendizabal; Jun Yu; Xenophon Papademetris; William C Sessa; Albert J Sinusas
Serial noninvasive targeted imaging of peripheral angiogenesis: validation and application of a semiautomated quantitative approach.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(8):1356-63.
2009: William C Sessa
Molecular control of blood flow and angiogenesis: role of nitric oxide.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():35-7.
2009: Carlos Fernández-Hernando; Jun Yu; Yajaira Suárez; Christoph Rahner; Alberto Dávalos; Miguel A Lasunción; William C Sessa
Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis.
Cell metabolism 2009;10(1):48-54.
2009: Yajaira Suárez; William C Sessa
MicroRNAs as novel regulators of angiogenesis.
Circulation research 2009;104(4):442-54.
2009: Michael Schleicher; Jun Yu; Takahisa Murata; Berhad Derakhshan; Dimitriy Atochin; Li Qian; Satoshi Kashiwagi; Annarita Di Lorenzo; Kenneth D Harrison; Paul L Huang; William C Sessa
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
Science signaling 2009;2(82):ra41.
2008: Yajaira Suárez; Carlos Fernández-Hernando; Jun Yu; Scott A Gerber; Kenneth D Harrison; Jordan S Pober; M Luisa Iruela-Arispe; Matthias Merkenschlager; William C Sessa
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14082-7.
2008: Marie M Krady; Jianmin Zeng; Jun Yu; Susan MacLauchlan; Eleni A Skokos; Weiming Tian; Paul Bornstein; William C Sessa; Themis R Kyriakides
Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis.
The American journal of pathology 2008;173(3):879-91.
2008: Elena Tourkina; Mathieu Richard; Pal Gööz; Michael Bonner; Jaspreet Pannu; Russell A Harley; Pascal N Bernatchez; William C Sessa; Richard M Silver; Stanley Hoffman
Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo.
American journal of physiology. Lung cellular and molecular physiology 2008;294(5):L843-61.
2008: Michael Schleicher; Benjamin R Shepherd; Yajaira Suarez; Carlos Fernandez-Hernando; Jun Yu; Yong Pan; Lisette Acevedo; Gerald S Shadel; William C Sessa
Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence.
The Journal of cell biology 2008;180(1):101-12.
2008: Robert Qing Miao; Jason Fontana; David J Fulton; Michelle I Lin; Kenneth D Harrison; William C Sessa
Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(1):105-11.
2007: Carlos Fernández-Hernando; Eric Ackah; Jun Yu; Yajaira Suárez; Takahisa Murata; Yasuko Iwakiri; Jay Prendergast; Robert Qing Miao; Morris J Birnbaum; William C Sessa
Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease.
Cell metabolism 2007;6(6):446-57.
2007: Pascal N Bernatchez; Lisette Acevedo; Carlos Fernandez-Hernando; Takahisa Murata; Cécile Chalouni; Jiae Kim; Hediye Erdjument-Bromage; Vijay Shah; Jean-Philippe Gratton; Elizabeth McNally; Paul Tempst; William C Sessa
Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.
The Journal of biological chemistry 2007;282(42):30745-53.
2007: Lei Li; Koji Hisamoto; Kyung Hee Kim; M Page Haynes; Philip M Bauer; Archana Sanjay; Mark Collinge; Roland Baron; William C Sessa; Jeffrey R Bender
Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16468-73.
2007: Jordan S Pober; William C Sessa
Evolving functions of endothelial cells in inflammation.
Nature reviews. Immunology 2007;7(10):803-15.
2007: Takahisa Murata; Michelle I Lin; Yan Huang; Jun Yu; Philip M Bauer; Frank J Giordano; William C Sessa
Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.
The Journal of experimental medicine 2007;204(10):2373-82.
2007: Dmitriy N Atochin; Annie Wang; Victor W T Liu; Jeffrey D Critchlow; Ana Paula V Dantas; Robin C Looft-Wilson; Takahisa Murata; Salvatore Salomone; Hwa Kyoung Shin; Cenk Ayata; Michael A Moskowitz; Thomas Michel; William C Sessa; Paul L Huang
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
The Journal of clinical investigation 2007;117(7):1961-7.
2007: Fabio A Kudo; Akihito Muto; Stephen P Maloney; Jose M Pimiento; Sonia Bergaya; Tamara N Fitzgerald; Tormod S Westvik; Jared C Frattini; Christopher K Breuer; Charles H Cha; Toshiya Nishibe; George Tellides; William C Sessa; Alan Dardik
Venous identity is lost but arterial identity is not gained during vein graft adaptation.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1562-71.
2007: Takahisa Murata; Michelle I Lin; Radu V Stan; Philip M Bauer; Jun Yu; William C Sessa
Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells.
The Journal of biological chemistry 2007;282(22):16631-43.
2007: Yajaira Suárez; Carlos Fernández-Hernando; Jordan S Pober; William C Sessa
Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells.
Circulation research 2007;100(8):1164-73.
2007: Jacek J Paszkowiak; Stephen P Maloney; Fabio A Kudo; Akihito Muto; Desarom Teso; Reuben C Rutland; Tormod S Westvik; Jose M Pimiento; George Tellides; William C Sessa; Alan Dardik
Evidence supporting changes in Nogo-B levels as a marker of neointimal expansion but not adaptive arterial remodeling.
Vascular pharmacology 2007;46(4):293-301.
2007: Michelle I Lin; Jun Yu; Takahisa Murata; William C Sessa
Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth.
Cancer research 2007;67(6):2849-56.
2007: Haifeng Zhang; Yan Luo; Wei Zhang; Yun He; Shengchuan Dai; Rong Zhang; Yan Huang; Pascal N Bernatchez; Frank J Giordano; Gerald Shadel; William C Sessa; Wang Min
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions.
The American journal of pathology 2007;170(3):1108-20.
2007: Ethan Marin; William C Sessa
Role of endothelial-derived nitric oxide in hypertension and renal disease.
Current opinion in nephrology and hypertension 2007;16(2):105-10.
2006: Yasuko Iwakiri; Ayano Satoh; Suvro Chatterjee; Derek Toomre; Cecile M Chalouni; David J Fulton; Roberto J Groszmann; Vijay H Shah; William C Sessa
Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19777-82.
2006: Dianhong Luo; Yan Luo; Yun He; Haifeng Zhang; Rong Zhang; Xianghong Li; Wawrzyniec L Dobrucki; Al J Sinusas; William C Sessa; Wang Min
Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis.
The American journal of pathology 2006;169(5):1886-98.
2006: Yun He; Yan Luo; Shibo Tang; Iiro Rajantie; Petri Salven; Matthias Heil; Rong Zhang; Dianhong Luo; Xianghong Li; Hongbo Chi; Jun Yu; Peter Carmeliet; Wolfgang Schaper; Albert J Sinusas; William C Sessa; Kari Alitalo; Wang Min
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis.
The Journal of clinical investigation 2006;116(9):2344-55.
2006: Carlos Fernández-Hernando; Masaki Fukata; Pascal N Bernatchez; Yuko Fukata; Michelle I Lin; David S Bredt; William C Sessa
Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase.
The Journal of cell biology 2006;174(3):369-77.
2006: Robert Qing Miao; Yuan Gao; Kenneth D Harrison; Jay Prendergast; Lisette Acevedo; Jun Yu; Fenghua Hu; Stephen M Strittmatter; William C Sessa
Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):10997-1002.
2006: Vineet Bhandari; Rayman Choo-Wing; Svetlana Chapoval; Chun Geun Lee; C Tang; Yoon-Keun Kim; Bing Ma; Peter Baluk; Michelle I Lin; Donald M McDonald; Robert J Homer; William C Sessa; Jack A Elias
Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):11021-6.
2006: Jun Yu; Sonia Bergaya; Takahisa Murata; Ilkay F Alp; Michael P Bauer; Michelle I Lin; Marek Drab; Teymuras V Kurzchalia; Radu V Stan; William C Sessa
Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels.
The Journal of clinical investigation 2006;116(5):1284-91.
2006: Juan G Abraldes; Yasuko Iwakiri; Mauricio R Loureiro-Silva; Omar Haq; William C Sessa; Roberto J Groszmann
Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(5):G980-7.
2006: Jun Yu; Li Lei; Yuxin Liang; Linda Hinh; Reed P Hickey; Yan Huang; Dinggang Liu; Jennifer L Yeh; Edward J Rebar; Casey Case; Kaye Spratt; William C Sessa; Frank J Giordano
An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):479-81.
2005: Jun Yu; Ebo D deMuinck; Zhenwu Zhuang; Mary Drinane; Katalin Kauser; Gabor M Rubanyi; Hu Sheng Qian; Takahisa Murata; Bruno Escalante; William C Sessa
Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10999-1004.
2005: Eric Ackah; Jun Yu; Stefan Zoellner; Yasuko Iwakiri; Carsten Skurk; Rei Shibata; Noriyuki Ouchi; Rachael Easton; Gennaro Galasso; Morris J Birnbaum; Kenneth Walsh; William C Sessa
Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.
The Journal of clinical investigation 2005;115(8):2119-27.
2005: Rong Zhang; Dianhong Luo; Robert Miao; Lanfang Bai; Qingyuan Ge; William C Sessa; Wang Min
Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis.
Oncogene 2005;24(24):3954-63.
2005: William C Sessa
Regulation of endothelial derived nitric oxide in health and disease.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():15-8.
2005: Mariarosaria Bucci; Fiorentina Roviezzo; Inmaculada Posadas; Jun Yu; Luca Parente; William C Sessa; Louis J Ignarro; Giuseppe Cirino
Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):904-8.
2005: Pascal N Bernatchez; Philip M Bauer; Jun Yu; Jay Prendergast; Pingnian He; William C Sessa
Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):761-6.
2005: Philip M Bauer; Jun Yu; Yan Chen; Reed Hickey; Pascal N Bernatchez; Robin C Looft-Wilson; Yan Huang; Frank Giordano; Radu V Stan; William C Sessa
Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):204-9.
2004: Michelle I Lin; William C Sessa
Antiangiogenic therapy: creating a unique "window" of opportunity.
Cancer cell 2004;6(6):529-31.
2004: Kian Peng Koh; Yinong Wang; Tai Yi; Adam Shiao; Marc I Lorber; William C Sessa; George Tellides; Jordan S Pober
T cell-mediated vascular dysfunction of human allografts results from IFN-gamma dysregulation of NO synthase.
The Journal of clinical investigation 2004;114(6):846-56.
2004: David J Fulton; Roger Babbitt; Stefan Zoellner; Jason Fontana; Lisette Acevedo; Timothy J McCabe; Yasuko Iwakiri; William C Sessa
Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release.
The Journal of biological chemistry 2004;279(29):30349-57.
2004: Jean-Philippe Gratton; Pascal N Bernatchez; William C Sessa
Caveolae and caveolins in the cardiovascular system.
Circulation research 2004;94(11):1408-17.
2004: William C Sessa
eNOS at a glance.
Journal of cell science 2004;117(Pt 12):2427-9.
2004: Lisette Acevedo; Jun Yu; Hediye Erdjument-Bromage; Robert Qing Miao; Ji-Eun Kim; David J Fulton; Paul Tempst; Stephen M Strittmatter; William C Sessa
A new role for Nogo as a regulator of vascular remodeling.
Nature medicine 2004;10(4):382-8.
2004: Mariarosaria Bucci; Fiorentina Roviezzo; Vincenzo Brancaleone; Michelle I Lin; Annarita Di Lorenzo; Carla Cicala; Aldo Pinto; William C Sessa; Silvana Farneti; Stefano Fiorucci; Giuseppe Cirino
Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):721-6.
2004: Yinong Wang; William R Burns; Paul C Y Tang; Tai Yi; Jeffrey S Schechner; Hans-Günter Zerwes; William C Sessa; Marc I Lorber; Jordan S Pober; George Tellides
Interferon-gamma plays a nonredundant role in mediating T cell-dependent outward vascular remodeling of allogeneic human coronary arteries.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(3):606-8.
2004: Geoffrey W Payne; Joseph A Madri; William C Sessa; Steven S Segal
Histamine inhibits conducted vasodilation through endothelium-derived NO production in arterioles of mouse skeletal muscle.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):280-6.
2004: Andreas Papapetropoulos; David J Fulton; Michelle I Lin; Jason Fontana; Timothy J McCabe; Stefan Zoellner; Guillermo García-Cardeña; Zongmin Zhou; Jean-Philippe Gratton; William C Sessa
Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein.
Molecular pharmacology 2004;65(2):407-15.
2003: Richard D Minshall; William C Sessa; Radu V Stan; Richard G W Anderson; Asrar B Malik
Caveolin regulation of endothelial function.
American journal of physiology. Lung cellular and molecular physiology 2003;285(6):L1179-83.
2003: Michelle I Lin; David J Fulton; Roger Babbitt; Ingrid Fleming; Rudi Busse; Kirkwood A Pritchard; William C Sessa
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production.
The Journal of biological chemistry 2003;278(45):44719-26.
2003: Ming-Hung Tsai; Yasuko Iwakiri; Gregory W Cadelina; William C Sessa; Roberto J Groszmann
Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats.
Gastroenterology 2003;125(5):1452-61.
2003: Yong BOO; George P Sorescu; Philip M Bauer; David J Fulton; Bruce E Kemp; David G Harrison; William C Sessa; Hanjoong Jo
Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase.
Free radical biology & medicine 2003;35(7):729-41.
2003: Geoffrey W Payne; Joseph A Madri; William C Sessa; Steven S Segal
Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice.
American journal of physiology. Heart and circulatory physiology 2003;285(2):H493-8.
2003: Jean-Philippe Gratton; Michelle I Lin; Jun Yu; Erik D Weiss; Zao Li Jiang; Todd A Fairchild; Yasuko Iwakiri; Roberto J Groszmann; Kevin P Claffey; Yung Chi Cheng; William C Sessa
Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice.
Cancer cell 2003;4(1):31-9.
2003: Grzegorz Sowa; Marc Pypaert; David J Fulton; William C Sessa
The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6511-6.
2003: Philip M Bauer; David J Fulton; Yong BOO; George P Sorescu; Bruce E Kemp; Hanjoong Jo; William C Sessa
Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase.
The Journal of biological chemistry 2003;278(17):14841-9.
2003: Jean-Philippe Gratton; Jun Yu; Jason W Griffith; Roger Babbitt; Ramona S Scotland; Reed Hickey; Frank J Giordano; William C Sessa
Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo.
Nature medicine 2003;9(3):357-62.
2003: M Page Haynes; Lei Li; Diviya Sinha; Kerry S Russell; Koji Hisamoto; Roland Baron; Mark Collinge; William C Sessa; Jeffrey R Bender
Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen.
The Journal of biological chemistry 2003;278(4):2118-23.
2002: Yasuko Iwakiri; Gregory W Cadelina; William C Sessa; Roberto J Groszmann
Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(5):G1074-81.
2002: Claudio Napoli; Eric Ackah; Filomena de Nigris; Piero Del Soldato; Francesco P D'Armiento; Emanuele Crimi; Mario Condorelli; William C Sessa
Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12467-70.
2002: Olivier Blanc-Brude; Jun Yu; Hector Simosa; Michael S Conte; William C Sessa; Dario C Altieri
Inhibitor of apoptosis protein survivin regulates vascular injury.
Nature medicine 2002;8(9):987-94.
2002: Jun Yu; Radu Daniel Rudic; William C Sessa
Nitric oxide-releasing aspirin decreases vascular injury by reducing inflammation and promoting apoptosis.
Laboratory investigation; a journal of technical methods and pathology 2002;82(7):825-32.
2002: Yasuko Iwakiri; Ming-Hung Tsai; Timothy J McCabe; Jean-Philippe Gratton; David J Fulton; Roberto J Groszmann; William C Sessa
Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H2084-90.
2002: Ramona S Scotland; Manuel Morales-Ruiz; Yan Chen; Jun Yu; Radu Daniel Rudic; David J Fulton; Jean-Philippe Gratton; William C Sessa
Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion.
Circulation research 2002;90(8):904-10.
2002: Jason Fontana; David J Fulton; Yan Chen; Todd A Fairchild; Timothy J McCabe; Naoya Fujita; Takashi Tsuruo; William C Sessa
Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release.
Circulation research 2002;90(8):866-73.
2002: Masahiko Akiyama; Daihiko Eguchi; Deborah Weiler; Timothy O'Brien; Imre Kovesdi; Ramona S Scotland; William C Sessa; Zvonimir S Katusic
Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries.
Stroke; a journal of cerebral circulation 2002;33(4):1071-6.
2002: David J Fulton; Jason Fontana; Grzegorz Sowa; Jean-Philippe Gratton; Michelle Lin; Kai-Xun Li; Belinda Michell; Bruce E Kemp; David M Rodman; William C Sessa
Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme.
The Journal of biological chemistry 2002;277(6):4277-84.
2001: David J Fulton; Jean-Philippe Gratton; William C Sessa
Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?
The Journal of pharmacology and experimental therapeutics 2001;299(3):818-24.
2001: Grzegorz Sowa; Marc Pypaert; William C Sessa
Distinction between signaling mechanisms in lipid rafts vs. caveolae.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):14072-7.
2001: Jean-Philippe Gratton; Manuel Morales-Ruiz; Yasuko Kureishi; David J Fulton; Kenneth Walsh; William C Sessa
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.
The Journal of biological chemistry 2001;276(32):30359-65.
2001: Todd A Fairchild; David J Fulton; J T Fontana; Jean-Philippe Gratton; Timothy J McCabe; William C Sessa
Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)-->Asp variant of human endothelial nitric-oxide synthase.
The Journal of biological chemistry 2001;276(28):26674-9.
2001: Manuel Morales-Ruiz; Meng-Jer Lee; S Zöllner; Jean-Philippe Gratton; Ramona S Scotland; I Shiojima; Kenneth Walsh; T Hla; William C Sessa
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells.
The Journal of biological chemistry 2001;276(22):19672-7.
2001: Mehdi Mesri; Manuel Morales-Ruiz; EJ Ackermann; C F Bennett; Jordan S Pober; William C Sessa; Dario C Altieri
Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.
The American journal of pathology 2001;158(5):1757-65.
2000: Mariarosaria Bucci; Jean-Philippe Gratton; Radu Daniel Rudic; Lisette Acevedo; Fiorentina Roviezzo; Giuseppe Cirino; William C Sessa
In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation.
Nature medicine 2000;6(12):1362-7.
2000: M Page Haynes; Diviya Sinha; Kerry S Russell; Mark Collinge; David J Fulton; Manuel Morales-Ruiz; William C Sessa; Jeffrey R Bender
Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells.
Circulation research 2000;87(8):677-82.
2000: Yasuko Kureishi; Z Luo; Ichiro Shiojima; Ann Bialik; David J Fulton; D J Lefer; William C Sessa; Kenneth Walsh
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.
Nature medicine 2000;6(9):1004-10.
2000: Mariarosaria Bucci; Fiorentina Roviezzo; Carla Cicala; William C Sessa; Giuseppe Cirino
Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo.
British journal of pharmacology 2000;131(1):13-6.
2000: Z Luo; Y Fujio; Yasuko Kureishi; Radu Daniel Rudic; G Daumerie; David J Fulton; William C Sessa; Kenneth Walsh
Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo.
The Journal of clinical investigation 2000;106(4):493-9.
2000: Jean-Philippe Gratton; Jason Fontana; Daniel S O'Connor; Guillermo García-Cardeña; Timothy J McCabe; William C Sessa
Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.
The Journal of biological chemistry 2000;275(29):22268-72.
2000: Radu Daniel Rudic; Mariarosaria Bucci; David J Fulton; Steven S Segal; William C Sessa
Temporal events underlying arterial remodeling after chronic flow reduction in mice: correlation of structural changes with a deficit in basal nitric oxide synthesis.
Circulation research 2000;86(11):1160-6.
2000: Manuel Morales-Ruiz; David J Fulton; Grzegorz Sowa; Lucia R Languino; Y Fujio; Kenneth Walsh; William C Sessa
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt.
Circulation research 2000;86(8):892-6.
2000: Andreas Papapetropoulos; David J Fulton; Keyvan Mahboubi; R G Kalb; Daniel S O'Connor; F Li; Dario C Altieri; William C Sessa
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway.
The Journal of biological chemistry 2000;275(13):9102-5.
2000: Timothy J McCabe; David J Fulton; Linda Roman; William C Sessa
Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation.
The Journal of biological chemistry 2000;275(9):6123-8.
2000: Kerry S Russell; M Page Haynes; Teresa Caulin-Glaser; J Rosneck; William C Sessa; Jeffrey R Bender
Estrogen stimulates heat shock protein 90 binding to endothelial nitric oxide synthase in human vascular endothelial cells. Effects on calcium sensitivity and NO release.
The Journal of biological chemistry 2000;275(7):5026-30.
2000: David J Fulton; Andreas Papapetropoulos; X Zhang; John D Catravas; T H Hintze; William C Sessa
Quantification of eNOS mRNA in the canine cardiac vasculature by competitive PCR.
American journal of physiology. Heart and circulatory physiology 2000;278(2):H658-65.
2000: J E Hungerford; William C Sessa; Steven S Segal
Vasomotor control in arterioles of the mouse cremaster muscle.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(1):197-207.
1999: V Shah; M Toruner; F Haddad; Gregory W Cadelina; Andreas Papapetropoulos; K Choo; William C Sessa; Roberto J Groszmann
Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat.
Gastroenterology 1999;117(5):1222-8.
1999: Steven S Segal; S E Brett; William C Sessa
Codistribution of NOS and caveolin throughout peripheral vasculature and skeletal muscle of hamsters.
The American journal of physiology 1999;277(3 Pt 2):H1167-77.
1999: Andreas Papapetropoulos; Radu Daniel Rudic; William C Sessa
Molecular control of nitric oxide synthases in the cardiovascular system.
Cardiovascular research 1999;43(3):509-20.
1999: Grzegorz Sowa; Jian Liu; Andreas Papapetropoulos; M Rex-Haffner; Thomas E Hughes; William C Sessa
Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion.
The Journal of biological chemistry 1999;274(32):22524-31.
1999: V Shah; Reiner Wiest; Guillermo García-Cardeña; Gregory W Cadelina; Roberto J Groszmann; William C Sessa
Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension.
The American journal of physiology 1999;277(2 Pt 1):G463-8.
1999: David J Fulton; Jean-Philippe Gratton; Timothy J McCabe; Jason Fontana; Y Fujio; K Walsh; T F Franke; Andreas Papapetropoulos; William C Sessa
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt.
Nature 1999;399(6736):597-601.
1999: Reiner Wiest; V Shah; William C Sessa; Roberto J Groszmann
NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats.
The American journal of physiology 1999;276(4 Pt 1):G1043-51.
1999: Radu Daniel Rudic; William C Sessa
Nitric oxide in endothelial dysfunction and vascular remodeling: clinical correlates and experimental links.
American journal of human genetics 1999;64(3):673-7.
1999: Andreas Papapetropoulos; Guillermo García-Cardeña; T J Dengler; P C Maisonpierre; George D Yancopoulos; William C Sessa
Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors.
Laboratory investigation; a journal of technical methods and pathology 1999;79(2):213-23.
1998: M Rocío Sierra-Honigmann; Anjali K Nath; C Murakami; Guillermo García-Cardeña; Andreas Papapetropoulos; William C Sessa; Lisa A Madge; Jeffrey S Schechner; M B Schwabb; Peter J Polverini; Jaime Flores-Riveros
Biological action of leptin as an angiogenic factor.
Science (New York, N.Y.) 1998;281(5383):1683-6.
1998: Guillermo García-Cardeña; R Fan; V Shah; R Sorrentino; Giuseppe Cirino; Andreas Papapetropoulos; William C Sessa
Dynamic activation of endothelial nitric oxide synthase by Hsp90.
Nature 1998;392(6678):821-4.
1998: Andreas Papapetropoulos; P Piccardoni; Giuseppe Cirino; Mariarosaria Bucci; R Sorrentino; C Cicala; K Johnson; Venetia Zachariou; William C Sessa; Dario C Altieri
Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4738-42.
1998: LE Olsson; Marcia A Wheeler; William C Sessa; Robert M Weiss
Bladder instillation and intraperitoneal injection of Escherichia coli lipopolysaccharide up-regulate cytokines and iNOS in rat urinary bladder.
The Journal of pharmacology and experimental therapeutics 1998;284(3):1203-8.
1998: Radu Daniel Rudic; Edward Shesely; Nobuyo Maeda; Oliver Smithies; Steven S Segal; William C Sessa
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
The Journal of clinical investigation 1998;101(4):731-6.
1998: Amy S Woodard; Guillermo García-Cardeña; M Leong; Joseph A Madri; William C Sessa; Lucia R Languino
The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration.
Journal of cell science 1998;111 ( Pt 4)():469-78.
1998: V Shah; Guillermo García-Cardeña; William C Sessa; Roberto J Groszmann
The hepatic circulation in health and disease: report of a single-topic symposium.
Hepatology (Baltimore, Md.) 1998;27(1):279-88.
1997: Andreas Papapetropoulos; Guillermo García-Cardeña; Joseph A Madri; William C Sessa
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.
The Journal of clinical investigation 1997;100(12):3131-9.
1997: V Shah; F G Haddad; Guillermo García-Cardeña; J A Frangos; Albert Mennone; Roberto J Groszmann; William C Sessa
Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids.
The Journal of clinical investigation 1997;100(11):2923-30.
1997: Teresa Caulin-Glaser; Guillermo García-Cardeña; Philip M Sarrel; William C Sessa; Jeffrey R Bender
17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization.
Circulation research 1997;81(5):885-92.
1997: Guillermo García-Cardeña; Pavel Martasek; Bettie Sue Masters; P M Skidd; J Couet; Shengwen Li; M P Lisanti; William C Sessa
Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo.
The Journal of biological chemistry 1997;272(41):25437-40.
1997: Jian Liu; Thomas E Hughes; William C Sessa
The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study.
The Journal of cell biology 1997;137(7):1525-35.
1997: Andreas Papapetropoulos; K M Desai; Radu Daniel Rudic; B Mayer; Rong Zhang; M P Ruiz-Torres; Guillermo García-Cardeña; Joseph A Madri; William C Sessa
Nitric oxide synthase inhibitors attenuate transforming-growth-factor-beta 1-stimulated capillary organization in vitro.
The American journal of pathology 1997;150(5):1835-44.
1997: Marcia A Wheeler; S D Smith; Guillermo García-Cardeña; C F Nathan; Robert M Weiss; William C Sessa
Bacterial infection induces nitric oxide synthase in human neutrophils.
The Journal of clinical investigation 1997;99(1):110-6.
1996: SD Smith; Marcia A Wheeler; R Zhang; E D Weiss; M I Lorber; William C Sessa; Robert M Weiss
Nitric oxide synthase induction with renal transplant rejection or infection.
Kidney international 1996;50(6):2088-93.
1996: Edward Shesely; Nobuyo Maeda; Hyung-Suk Kim; K M Desai; John Krege; Victor E Laubach; P A Sherman; William C Sessa; Oliver Smithies
Elevated blood pressures in mice lacking endothelial nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13176-81.
1996: Guillermo García-Cardeña; R Fan; David F Stern; J Liu; William C Sessa
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1.
The Journal of biological chemistry 1996;271(44):27237-40.
1996: J Liu; Guillermo García-Cardeña; William C Sessa
Palmitoylation of endothelial nitric oxide synthase is necessary for optimal stimulated release of nitric oxide: implications for caveolae localization.
Biochemistry 1996;35(41):13277-81.
1996: Guillermo García-Cardeña; Phil Oh; J Liu; Jan Schnitzer; William C Sessa
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6448-53.
1996: Pavel Martasek; Q Liu; J Liu; Linda Roman; Steven S Gross; William C Sessa; Bettie Sue Masters
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.
Biochemical and biophysical research communications 1996;219(2):359-65.
1995: J Liu; Guillermo García-Cardeña; William C Sessa
Biosynthesis and palmitoylation of endothelial nitric oxide synthase: mutagenesis of palmitoylation sites, cysteines-15 and/or -26, argues against depalmitoylation-induced translocation of the enzyme.
Biochemistry 1995;34(38):12333-40.
1995: M A Awolesi; William C Sessa; Bauer E Sumpio
Cyclic strain upregulates nitric oxide synthase in cultured bovine aortic endothelial cells.
The Journal of clinical investigation 1995;96(3):1449-54.
1995: William C Sessa; Guillermo García-Cardeña; J Liu; A Keh; Jennifer Pollock; J Bradley; S Thiru; I M Braverman; K M Desai
The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide.
The Journal of biological chemistry 1995;270(30):17641-4.
1995: R Zhang; W Min; William C Sessa
Functional analysis of the human endothelial nitric oxide synthase promoter. Sp1 and GATA factors are necessary for basal transcription in endothelial cells.
The Journal of biological chemistry 1995;270(25):15320-6.
1994: M A Awolesi; M D Widmann; William C Sessa; Bauer E Sumpio
Cyclic strain increases endothelial nitric oxide synthase activity.
Surgery 1994;116(2):439-44; discussion 444-5.
1994: P Rosenkranz-Weiss; William C Sessa; S Milstien; S Kaufman; C A Watson; Jordan S Pober
Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.
The Journal of clinical investigation 1994;93(5):2236-43.
1994: William C Sessa
The nitric oxide synthase family of proteins.
Journal of vascular research 1994;31(3):131-43.
1994: J Liu; William C Sessa
Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase.
The Journal of biological chemistry 1994;269(16):11691-4.
1993: Bruno A Escalante; K Omata; William C Sessa; S G Lee; John R Falck; Michal L Schwartzman
20-hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries.
European journal of pharmacology 1993;235(1):1-7.
1992: M Hecker; I Siegle; H Macarthur; William C Sessa; JR Vane
Role of intracellular thiols in release of EDRF from cultured endothelial cells.
The American journal of physiology 1992;262(3 Pt 2):H888-96.
1991: K M Desai; A Zembowicz; William C Sessa; JR Vane
Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11490-4.
1991: A Zembowicz; M Hecker; H Macarthur; William C Sessa; JR Vane
Nitric oxide and another potent vasodilator are formed from NG-hydroxy-L-arginine by cultured endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11172-6.
1991: Vincenzo Mollace; Daniela Salvemini; William C Sessa; JR Vane
Inhibition of human platelet aggregation by endothelium-derived relaxing factor, sodium nitroprusside or iloprost is potentiated by captopril and reduced thiols.
The Journal of pharmacology and experimental therapeutics 1991;258(3):820-3.
1991: P J Pagano; L Lin; William C Sessa; Alberto Nasjletti
Arachidonic acid elicits endothelium-dependent release from the rabbit aorta of a constrictor prostanoid resembling prostaglandin endoperoxides.
Circulation research 1991;69(2):396-405.
1991: K M Desai; William C Sessa; JR Vane
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid.
Nature 1991;351(6326):477-9.
1991: William C Sessa; S Kaw; M Hecker; JR Vane
The biosynthesis of endothelin-1 by human polymorphonuclear leukocytes.
Biochemical and biophysical research communications 1991;174(2):613-8.
1991: William C Sessa; S Kaw; A Zembowicz; E Anggård; M Hecker; JR Vane
Human polymorphonuclear leukocytes generate and degrade endothelin-1 by two distinct neutral proteases.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S34-8.
1990: William C Sessa; Perry V Halushka; A Okwu; Alberto Nasjletti
Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone.
Circulation research 1990;67(6):1562-9.
1990: M Hecker; William C Sessa; H J Harris; E E Anggård; JR Vane
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8612-6.
1990: William C Sessa; M Hecker; J A Mitchell; JR Vane
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8607-11.
1990: T A Swierkosz; J A Mitchell; William C Sessa; M Hecker; JR Vane
L-glutamine inhibits the release of endothelium-derived relaxing factor from the rabbit aorta.
Biochemical and biophysical research communications 1990;172(1):143-8.
1990: M Hecker; J A Mitchell; T A Swierkosz; William C Sessa; JR Vane
Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells.
British journal of pharmacology 1990;101(2):237-9.
1990: Bruno A Escalante; William C Sessa; John R Falck; P Yadagiri; Michal L Schwartzman
Cytochrome P450-dependent arachidonic acid metabolites, 19- and 20-hydroxyeicosatetraenoic acids, enhance sodium-potassium ATPase activity in vascular smooth muscle.
Journal of cardiovascular pharmacology 1990;16(3):438-43.
1990: William C Sessa; K M Mullane
Release of a neutrophil-derived vasoconstrictor agent which augments platelet-induced contractions of blood vessels in vitro.
British journal of pharmacology 1990;99(3):553-9.
1990: William C Sessa; Alberto Nasjletti
Dexamethasone selectively attenuates prostanoid-induced vasoconstrictor responses in vitro.
Circulation research 1990;66(2):383-8.
1989: William C Sessa; Nader G Abraham; Bruno A Escalante; Michal L Schwartzman
Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats.
Journal of hypertension 1989;7(1):37-42.
1989: Bruno A Escalante; William C Sessa; John R Falck; P Yadagiri; Michal L Schwartzman
Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase.
The Journal of pharmacology and experimental therapeutics 1989;248(1):229-32.
1987: K Mullane; M A Hatala; R Kraemer; William C Sessa; W Westlin
Myocardial salvage induced by REV-5901: an inhibitor and antagonist of the leukotrienes.
Journal of cardiovascular pharmacology 1987;10(4):398-406.