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Kenneth Setchell

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
19
Heubi, James
15
Lephart, Edwin
10
Crosignani, Andrea
10
Zimmer-Nechemias, Linda
9
Lund, Trent
9
Podda, Mauro
8
Rodrigues, Cecília
8
Brown, Nadine
7
Battezzati, Pier Maria
6
Clerici, Carlo
6
Morelli, Antonio
5
Kren, Betsy
5
Russell, David
5
Steer, Clifford
5
Thigpen, Julius

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Publications

TOP 3
Setchell Kenneth D R; Zhao Xueheng; Shoaf Susan E; Ragland Karen
The pharmacokinetics of S-(-)equol administered as SE5-OH tablets to healthy postmenopausal women.
Gonzales Emmanuel; Gerhardt Marie F; Fabre Monique; Setchell Kenneth D R; Davit-Spraul Anne; Vincent Isabelle; Heubi James E; Bernard Olivier; Jacquemin Emmanuel
Oral cholic acid for hereditary defects of primary bile acid synthesis: a safe and effective long-term therapy.
Messina Mark; Watanabe Shaw; Setchell Kenneth D R
Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment.

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All Publications

2009: Setchell Kenneth D R; Zhao Xueheng; Shoaf Susan E; Ragland Karen
The pharmacokinetics of S-(-)equol administered as SE5-OH tablets to healthy postmenopausal women.
The Journal of nutrition 2009;139(11):2037-43.
2009: Gonzales Emmanuel; Gerhardt Marie F; Fabre Monique; Setchell Kenneth D R; Davit-Spraul Anne; Vincent Isabelle; Heubi James E; Bernard Olivier; Jacquemin Emmanuel
Oral cholic acid for hereditary defects of primary bile acid synthesis: a safe and effective long-term therapy.
Gastroenterology 2009;137(4):1310-1320.e1-3.
2009: Messina Mark; Watanabe Shaw; Setchell Kenneth D R
Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment.
The Journal of nutrition 2009;139(4):796S-802S.
2009: Gleason Carey E; Carlsson Cynthia M; Barnet Jodi H; Meade Sarah A; Setchell Kenneth D R; Atwood Craig S; Johnson Sterling C; Ries Michele L; Asthana Sanjay
A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.
Age and ageing 2009;38(1):86-93.
2008: Frankenberg Tamara; Miloh Tamir; Chen Frank Y; Ananthanarayanan Meena; Sun An-Qiang; Balasubramaniyan Natarajan; Arias Irwin; Setchell Kenneth D R; Suchy Frederick J; Shneider Benjamin L
The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.
Hepatology (Baltimore, Md.) 2008;48(6):1896-905.
2008: Legg Russell L; Tolman Jessica R; Lovinger Cameron T; Lephart Edwin D; Setchell Kenneth D R; Christensen Merrill J
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.
Reproductive biology and endocrinology : RB&E 2008;6():57.
2007: Thigpen Julius E; Setchell Kenneth D R; Padilla-Banks Elizabeth; Haseman Joseph K; Saunders Hannah E; Caviness Gordon F; Kissling Grace E; Grant Mary G; Forsythe Diane B
Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague-Dawley rats.
Environmental health perspectives 2007;115(12):1717-26.
2007: Thomas Emily K; Cancelas Jose A; Chae Hee-Don; Cox Adrienne D; Keller Patricia J; Perrotti Danilo; Neviani Paolo; Druker Brian J; Setchell Kenneth D R; Zheng Yi; Harris Chad E; Williams David A
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease.
Cancer cell 2007;12(5):467-78.
2007: Clerici Carlo; Setchell Kenneth D R; Battezzati Pier Maria; Pirro Matteo; Giuliano Vittorio; Asciutti Stefania; Castellani Danilo; Nardi Elisabetta; Sabatino Giuseppe; Orlandi Stefano; Baldoni Monia; Morelli Olivia; Mannarino Elmo; Morelli Antonio
Pasta naturally enriched with isoflavone aglycons from soy germ reduces serum lipids and improves markers of cardiovascular risk.
The Journal of nutrition 2007;137(10):2270-8.
2007: Heubi James E; Setchell Kenneth D R; Bove Kevin E
Inborn errors of bile acid metabolism.
Seminars in liver disease 2007;27(3):282-94.
2007: Shea Heidi C; Head Daphne D; Setchell Kenneth D R; Russell David W
Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11526-33.
2006: Setchell Kenneth D R; Cole Sidney J
Method of defining equol-producer status and its frequency among vegetarians.
The Journal of nutrition 2006;136(8):2188-93.
2006: Setchell Kenneth D R; Heubi James E
Defects in bile acid biosynthesis--diagnosis and treatment.
Journal of pediatric gastroenterology and nutrition 2006;43 Suppl 1():S17-22.
2006: Clerici Carlo; Castellani Danilo; Asciutti Stefania; Pellicciari Roberto; Setchell Kenneth D R; O'Connell Nancy C; Sadeghpour Bahman; Camaioni Emidio; Fiorucci Stefano; Renga Barbara; Nardi Elisabetta; Sabatino Giuseppe; Clementi Mattia; Giuliano Vittorio; Baldoni Monia; Orlandi Stefano; Mazzocchi Alessandro; Morelli Antonio; Morelli Olivia
3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats.
Toxicology and applied pharmacology 2006;214(2):199-208.
2006: Setchell Kenneth D R
Assessing risks and benefits of genistein and soy.
Environmental health perspectives 2006;114(6):A332-3.
2006: Gardner Paul R; Gardner Anne M; Brashear Wayne T; Suzuki Tomohiko; Hvitved Angela N; Setchell Kenneth D R; Olson John S
Hemoglobins dioxygenate nitric oxide with high fidelity.
Journal of inorganic biochemistry 2006;100(4):542-50.
2006: Woollett L A; Wang Y; Buckley D D; Yao L; Chin S; Granholm N; Jones P J H; Setchell K D R; Tso P; Heubi J E
Micellar solubilisation of cholesterol is essential for absorption in humans.
Gut 2006;55(2):197-204.
2006: Cassidy Aedin; Brown Jonathan E; Hawdon Anne; Faughnan Marian S; King Laurence J; Millward Joe; Zimmer-Nechemias Linda; Wolfe Brian; Setchell Kenneth D R
Factors affecting the bioavailability of soy isoflavones in humans after ingestion of physiologically relevant levels from different soy foods.
The Journal of nutrition 2006;136(1):45-51.
2005: Waters Paula J; Khashu Minesh; Lillquist Yolanda; Senger Christof; Mattman Andre; Demos Michelle; Setchell Kenneth; Rupar Anthony; Scott Patrick; Blau Nenad; Vallance Hilary D
Neonatal hyperphenylalaninemia, perinatal hemochromatosis, and renal tubulopathy: a unique patient or a novel metabolic disorder?
Molecular genetics and metabolism 2005;86 Suppl 1():S148-52.
2005: Puglielli Luigi; Friedlich Avi L; Setchell Kenneth D R; Nagano Seiichi; Opazo Carlos; Cherny Robert A; Barnham Kevin J; Wade John D; Melov Simon; Kovacs Dora M; Bush Ashley I
Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.
The Journal of clinical investigation 2005;115(9):2556-63.
2005: Stephenson T J; Setchell K D R; Kendall C W C; Jenkins D J A; Anderson J W; Fanti P
Effect of soy protein-rich diet on renal function in young adults with insulin-dependent diabetes mellitus.
Clinical nephrology 2005;64(1):1-11.
2005: Donovan J M; Von Bergmann K; Setchell K D R; Isaacsohn J; Pappu A S; Illingworth D R; Olson T; Burke S K
Effects of colesevelam HC1 on sterol and bile acid excretion in patients with type IIa hypercholesterolemia.
Digestive diseases and sciences 2005;50(7):1232-8.
2005: Setchell Kenneth D R; Clerici Carlo; Lephart Edwin D; Cole Sidney J; Heenan Claire; Castellani Danilo; Wolfe Brian E; Nechemias-Zimmer Linda; Brown Nadine M; Lund Trent D; Handa Robert J; Heubi James E
S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora.
The American journal of clinical nutrition 2005;81(5):1072-9.
2005: Lephart Edwin D; Setchell Kenneth D R; Lund Trent D
Phytoestrogens: hormonal action and brain plasticity.
Brain research bulletin 2005;65(3):193-8.
2005: Setchell K D R; Galzigna L; O'Connell N; Brunetti G; Tauschel H-D
Bioequivalence of a new liquid formulation of ursodeoxycholic acid (Ursofalk suspension) and Ursofalk capsules measured by plasma pharmacokinetics and biliary enrichment.
Alimentary pharmacology & therapeutics 2005;21(6):709-21.
2005: Setchell Kenneth D R; Brzezinski Amnon; Brown Nadine M; Desai Pankaj B; Melhem Murad; Meredith Trevor; Zimmer-Nechimias Linda; Wolfe Brian; Cohen Yoram; Blatt Yoav
Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women.
Journal of agricultural and food chemistry 2005;53(6):1938-44.
2005: Bu Lihong; Setchell Kenneth D R; Lephart Edwin D
Influences of dietary soy isoflavones on metabolism but not nociception and stress hormone responses in ovariectomized female rats.
Reproductive biology and endocrinology : RB&E 2005;3():58.
2004: Lephart Edwin D; Porter James P; Hedges Dawson W; Lund Trent D; Setchell Kenneth D R
Phytoestrogens: implications in neurovascular research.
Current neurovascular research 2004;1(5):455-64.
2004: Lydeking-Olsen Eva; Beck-Jensen Jens-Erik; Setchell Kenneth D R; Holm-Jensen Trine
Soymilk or progesterone for prevention of bone loss--a 2 year randomized, placebo-controlled trial.
European journal of nutrition 2004;43(4):246-57.
2004: Bove Kevin E; Heubi James E; Balistreri William F; Setchell Kenneth D R
Bile acid synthetic defects and liver disease: a comprehensive review.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004;7(4):315-34.
2004: Vilca Melendez Hector; Rela Mohamed; Setchell Kenneth D R; Murphy Gerard M; Heaton Nigel D
Bile acids analysis: a tool to assess graft function in human liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2004;17(6):286-92.
2004: Smith Jeffery L; Lewindon Peter J; Hoskins Anita C; Pereira Tamara N; Setchell Kenneth D R; O'Connell Nancy C; Shepherd Ross W; Ramm Grant A
Endogenous ursodeoxycholic acid and cholic acid in liver disease due to cystic fibrosis.
Hepatology (Baltimore, Md.) 2004;39(6):1673-82.
2004: Erdman John W; Badger Thomas M; Lampe Johanna W; Setchell Kenneth D R; Messina Mark
Not all soy products are created equal: caution needed in interpretation of research results.
The Journal of nutrition 2004;134(5):1229S-1233S.
2004: Messina Mark; Erdman John; Setchell Kenneth D R
Introduction to and perspectives from the Fifth International Symposium on the Role of Soy in Preventing and Treating Chronic Disease.
The Journal of nutrition 2004;134(5):1205S-1206S.
2004: Lund Trent D; Munson Daniel J; Haldy Megan E; Setchell Kenneth D R; Lephart Edwin D; Handa Robert J
Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback.
Biology of reproduction 2004;70(4):1188-95.
2004: Lephart Edwin D; Setchell Kenneth D R; Handa Robert J; Lund Trent D
Behavioral effects of endocrine-disrupting substances: phytoestrogens.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2004;45(4):443-54.
2004: Thigpen Julius E; Setchell Kenneth D R; Saunders H E; Haseman J K; Grant M G; Forsythe D B
Selecting the appropriate rodent diet for endocrine disruptor research and testing studies.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2004;45(4):401-16.
2003: Thigpen Julius E; Haseman Joseph K; Saunders Hannah E; Setchell Kenneth D R; Grant Mary G; Forsythe Diane B
Dietary phytoestrogens accelerate the time of vaginal opening in immature CD-1 mice.
Comparative medicine 2003;53(6):607-15.
2003: Nallani Srikanth C; Glauser Tracy A; Hariparsad Niresh; Setchell Kenneth; Buckley Donna J; Buckley Arthur R; Desai Pankaj B
Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.
Epilepsia 2003;44(12):1521-8.
2003: Kritchevsky David; Tepper Shirley A; Czarnecki Susanne K; Wolfe Brian; Setchell Kenneth D R
Serum and aortic levels of phytosterols in rabbits fed sitosterol or sitostanol ester preparations.
Lipids 2003;38(11):1115-8.
2003: Kurbegov Amethyst C; Setchell Kenneth D R; Haas Joel E; Mierau Gary W; Narkewicz Michael; Bancroft John D; Karrer Frederick; Sokol Ronald J
Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile.
Gastroenterology 2003;125(4):1227-34.
2003: Setchell Kenneth D R; Lydeking-Olsen Eva
Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies.
The American journal of clinical nutrition 2003;78(3 Suppl):593S-609S.
2003: Setchell Kenneth D R; Cole Sidney J
Variations in isoflavone levels in soy foods and soy protein isolates and issues related to isoflavone databases and food labeling.
Journal of agricultural and food chemistry 2003;51(14):4146-55.
2003: Lephart E D; Rhees R W; Setchell K D R; Bu L H; Lund T D
Estrogens and phytoestrogens: brain plasticity of sexually dimorphic brain volumes.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):299-309.
2003: Cheng Jeffrey B; Jacquemin Emmanuel; Gerhardt Marie; Nazer Hisham; Cresteil Danièle; Heubi James E; Setchell Kenneth D R; Russell David W
Molecular genetics of 3beta-hydroxy-Delta5-C27-steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis and liver disease.
The Journal of clinical endocrinology and metabolism 2003;88(4):1833-41.
2003: Setchell Kenneth D R; Brown Nadine Maynard; Desai Pankaj B; Zimmer-Nechimias Linda; Wolfe Brian; Jakate Abhijeet S; Creutzinger Vivian; Heubi James E
Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes.
The Journal of nutrition 2003;133(4):1027-35.
2003: Setchell Kenneth D R; Faughnan Marian S; Avades Tony; Zimmer-Nechemias Linda; Brown Nadine M; Wolfe Brian E; Brashear Wayne T; Desai Panjak; Oldfield Mark F; Botting Nigel P; Cassidy Aedin
Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women.
The American journal of clinical nutrition 2003;77(2):411-9.
2003: Setchell Kenneth D R; Heubi James E; Bove Kevin E; O'Connell Nancy C; Brewsaugh Tracy; Steinberg Steven J; Moser Ann; Squires Robert H
Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy.
Gastroenterology 2003;124(1):217-32.
2003: Colombo Carla; Setchell Kenneth D R; Crosignani Andrea; Biffi Arianna; O'Connell Nancy; Agosti Massimo; Marini Antonio
Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs.
Biology of the neonate 2003;83(1):36-41.
2002: Setchell Kenneth D R; Brown Nadine M; Lydeking-Olsen Eva
The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones.
The Journal of nutrition 2002;132(12):3577-84.
2002: Heubi James E; Wiechmann David A; Creutzinger Vivian; Setchell Kenneth D R; Squires Robert; Couser Robert; Rhodes Philip
Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease.
The Journal of pediatrics 2002;141(2):237-42.
2002: Setchell Kenneth D R; Brown Nadine M; Zimmer-Nechemias Linda; Brashear Wayne T; Wolfe Brian E; Kirschner Abby S; Heubi James E
Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability.
The American journal of clinical nutrition 2002;76(2):447-53.
2002: Nicholls Jill; Lasley Bill L; Nakajima Steven T; Setchell Kenneth D R; Schneeman Barbara O
Effects of soy consumption on gonadotropin secretion and acute pituitary responses to gonadotropin-releasing hormone in women.
The Journal of nutrition 2002;132(4):708-14.
2002: Yao Lihang; Heubi James E; Buckley Donna D; Fierra Humberto; Setchell Kenneth D R; Granholm Norman A; Tso Patrick; Hui David Y; Woollett Laura A
Separation of micelles and vesicles within lumenal aspirates from healthy humans: solubilization of cholesterol after a meal.
Journal of lipid research 2002;43(4):654-60.
2002: Lephart Edwin D; West Timothy W; Weber K Scott; Rhees Reuben W; Setchell Kenneth D R; Adlercreutz Herman; Lund Trent D
Neurobehavioral effects of dietary soy phytoestrogens.
Neurotoxicology and teratology 2002;24(1):5-16.
2001: Setchell K D
Soy isoflavones--benefits and risks from nature's selective estrogen receptor modulators (SERMs).
Journal of the American College of Nutrition 2001;20(5 Suppl):354S-362S; discussion 381S-383S.
2001: Lund T D; Rhees R W; Setchell K D; Lephart E D
Altered sexually dimorphic nucleus of the preoptic area (SDN-POA) volume in adult Long-Evans rats by dietary soy phytoestrogens.
Brain research 2001;914(1-2):92-9.
2001: Scheiber M D; Liu J H; Subbiah M T; Rebar R W; Setchell K D
Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women.
Menopause (New York, N.Y.) 2001;8(5):384-92.
2001: Weber K S; Setchell K D; Stocco D M; Lephart E D
Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats.
The Journal of endocrinology 2001;170(3):591-9.
2001: Brown N M; Setchell K D
Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones.
Laboratory investigation; a journal of technical methods and pathology 2001;81(5):735-47.
2001: Setchell K D; Brown N M; Desai P; Zimmer-Nechemias L; Wolfe B E; Brashear W T; Kirschner A S; Cassidy A; Heubi J E
Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements.
The Journal of nutrition 2001;131(4 Suppl):1362S-75S.
2001: Weber K S; Setchell K D; Lephart E D
Maternal and perinatal brain aromatase: effects of dietary soy phytoestrogens.
Brain research. Developmental brain research 2001;126(2):217-21.
2001: Lund T D; West T W; Tian L Y; Bu L H; Simmons D L; Setchell K D; Adlercreutz H; Lephart E D
Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens.
BMC neuroscience 2001;2():20.
2000: Lephart E D; Thompson J M; Setchell K D; Adlercreutz H; Weber K S
Phytoestrogens decrease brain calcium-binding proteins but do not alter hypothalamic androgen metabolizing enzymes in adult male rats.
Brain research 2000;859(1):123-31.
2000: Setchell K D
Absorption and metabolism of soy isoflavones-from food to dietary supplements and adults to infants.
The Journal of nutrition 2000;130(3):654S-5S.
2000: Bove K E; Daugherty C C; Tyson W; Mierau G; Heubi J E; Balistreri W F; Setchell K D
Bile acid synthetic defects and liver disease.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2000;3(1):1-16.
1999: Shertzer H G; Puga A; Chang C; Smith P; Nebert D W; Setchell K D; Dalton T P
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones.
Chemico-biological interactions 1999;123(1):31-49.
1999: Thigpen J E; Setchell K D; Ahlmark K B; Locklear J; Spahr T; Caviness G F; Goelz M F; Haseman J K; Newbold R R; Forsythe D B
Phytoestrogen content of purified, open- and closed-formula laboratory animal diets.
Laboratory animal science 1999;49(5):530-6.
1999: Weber K S; Jacobson N A; Setchell K D; Lephart E D
Brain aromatase and 5alpha-reductase, regulatory behaviors and testosterone levels in adult rats on phytoestrogen diets.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;221(2):131-5.
1999: Thigpen J E; Setchell K D; Goelz M F; Forsythe D B
The phytoestrogen content of rodent diets.
Environmental health perspectives 1999;107(4):A182-3.
1999: Setchell K D; Cassidy A
Dietary isoflavones: biological effects and relevance to human health.
The Journal of nutrition 1999;129(3):758S-767S.
1999: Invernizzi P; Setchell K D; Crosignani A; Battezzati P M; Larghi A; O'Connell N C; Podda M
Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine-conjugated species in patients with primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1999;29(2):320-7.
1998: Setchell K D; Zimmer-Nechemias L; Cai J; Heubi J E
Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life.
The American journal of clinical nutrition 1998;68(6 Suppl):1453S-1461S.
1998: Setchell K D
Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones.
The American journal of clinical nutrition 1998;68(6 Suppl):1333S-1346S.
1998: Setchell K D; Schwarz M; O'Connell N C; Lund E G; Davis D L; Lathe R; Thompson H R; Weslie Tyson R; Sokol R J; Russell D W
Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.
The Journal of clinical investigation 1998;102(9):1690-703.
1997: Messina M; Barnes S; Setchell K D
Phyto-oestrogens and breast cancer.
Lancet 1997;350(9083):971-2.
1997: Invernizzi P; Salzman A L; Szabó C; Ueta I; O'Connor M; Setchell K D
Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo.
The American journal of physiology 1997;273(1 Pt 1):G131-8.
1997: Setchell K D; Zimmer-Nechemias L; Cai J; Heubi J E
Exposure of infants to phyto-oestrogens from soy-based infant formula.
Lancet 1997;350(9070):23-7.
1997: Setchell K D; Rodrigues C M; Clerici C; Solinas A; Morelli A; Gartung C; Boyer J
Bile acid concentrations in human and rat liver tissue and in hepatocyte nuclei.
Gastroenterology 1997;112(1):226-35.
1996: Schwarz M; Lund E G; Setchell K D; Kayden H J; Zerwekh J E; Björkhem I; Herz J; Russell D W
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.
The Journal of biological chemistry 1996;271(30):18024-31.
1996: Clerici C; Setchell K D; O'Connell N; Gentili G; Rusticali G; Aversa F; Balo' S; Modesto R; Morselli-Labate A M; Martelli M; Morelli A
Effect of ursodeoxycholic acid on hypertransaminasaemia and bile acid composition in patients undergoing bone marrow transplantation--a double-blind randomized control study.
The Italian journal of gastroenterology 1996;28(4):191-8.
1996: Crosignani A; Setchell K D; Invernizzi P; Larghi A; Rodrigues C M; Podda M
Clinical pharmacokinetics of therapeutic bile acids.
Clinical pharmacokinetics 1996;30(5):333-58.
1996: Crosignani A; Battezzati P M; Setchell K D; Invernizzi P; Covini G; Zuin M; Podda M
Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response study.
Digestive diseases and sciences 1996;41(4):809-15.
1996: Rodrigues C M; Kren B T; Steer C J; Setchell K D
Formation of delta 22-bile acids in rats is not gender specific and occurs in the peroxisome.
Journal of lipid research 1996;37(3):540-50.
1996: Setchell K D; Rodrigues C M; Podda M; Crosignani A
Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis.
Gut 1996;38(3):439-46.
1996: Rodrigues C M; Setchell K D
Performance characteristics of reversed-phase bonded silica cartridges for serum bile acid extraction.
Biomedical chromatography : BMC 1996;10(1):1-5.
1995: Kren B T; Rodrigues C M; Setchell K D; Steer C J
Posttranscriptional regulation of mRNA levels in rat liver associated with deoxycholic acid feeding.
The American journal of physiology 1995;269(6 Pt 1):G961-73.
1995: Rodrigues C M; Kren B T; Steer C J; Setchell K D
The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation.
Gastroenterology 1995;109(6):1835-44.
1995: Rodrigues C M; Kren B T; Steer C J; Setchell K D
Tauroursodeoxycholate increases rat liver ursodeoxycholate levels and limits lithocholate formation better than ursodeoxycholate.
Gastroenterology 1995;109(2):564-72.
1995: Setchell K D; Yamashita H; Rodrigues C M; O'Connell N C; Kren B T; Steer C J
delta 22-Ursodeoxycholic acid, a unique metabolite of administered ursodeoxycholic acid in rats, indicating partial beta-oxidation as a major pathway for bile acid metabolism.
Biochemistry 1995;34(13):4169-78.
1994: Dumaswala R; Berkowitz D; Setchell K D; Heubi J E
Effect of fasting on the enterohepatic circulation of bile acids in rats.
The American journal of physiology 1994;267(5 Pt 1):G836-42.
1993: Clerici C; Gentili G; Dozzini G; Distrutti E; Solinas A; Vedovelli A; Pelli M A; Bragetti P; Setchell K; Morelli A
[Chronic therapy with ursodeoxycholic acid in a child with Alagille syndrome]
La Pediatria medica e chirurgica : Medical and surgical pediatrics 1993;15(5):521-3.
1993: Dumaswala R; Setchell K D; Moyer M S; Suchy F J
An anion exchanger mediates bile acid transport across the placental microvillous membrane.
The American journal of physiology 1993;264(6 Pt 1):G1016-23.
1992: Colombo C; Crosignani A; Assaisso M; Battezzati P M; Podda M; Giunta A; Zimmer-Nechemias L; Setchell K D
Ursodeoxycholic acid therapy in cystic fibrosis-associated liver disease: a dose-response study.
Hepatology (Baltimore, Md.) 1992;16(4):924-30.
1992: Heubi J E; O'Connell N C; Setchell K D
Ileal resection/dysfunction in childhood predisposes to lithogenic bile only after puberty.
Gastroenterology 1992;103(2):636-40.
1992: Russell D W; Setchell K D
Bile acid biosynthesis.
Biochemistry 1992;31(20):4737-49.
1992: Setchell K D; Bragetti P; Zimmer-Nechemias L; Daugherty C; Pelli M A; Vaccaro R; Gentili G; Distrutti E; Dozzini G; Morelli A
Oral bile acid treatment and the patient with Zellweger syndrome.
Hepatology (Baltimore, Md.) 1992;15(2):198-207.
1991: Crosignani A; Podda M; Battezzati P M; Bertolini E; Zuin M; Watson D; Setchell K D
Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration.
Hepatology (Baltimore, Md.) 1991;14(6):1000-7.
1991: Watson D; Setchell K D; Ross R
Analysis of vitamin D and its metabolites using thermospray liquid chromatography/mass spectrometry.
Biomedical chromatography : BMC 1991;5(4):153-60.
1991: Crosignani A; Podda M; Bertolini E; Battezzati P M; Zuin M; Setchell K D
Failure of ursodeoxycholic acid to prevent a cholestatic episode in a patient with benign recurrent intrahepatic cholestasis: a study of bile acid metabolism.
Hepatology (Baltimore, Md.) 1991;13(6):1076-83.
1991: Crosignani A; Battezzati P M; Setchell K D; Camisasca M; Bertolini E; Roda A; Zuin M; Podda M
Effects of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis: a dose-response study.
Hepatology (Baltimore, Md.) 1991;13(2):339-44.
1990: Colombo C; Setchell K D; Podda M; Crosignani A; Roda A; Curcio L; Ronchi M; Giunta A
Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis.
The Journal of pediatrics 1990;117(3):482-9.
1990: Nakagawa M; Colombo C; Setchell K D
Comprehensive study of the biliary bile acid composition of patients with cystic fibrosis and associated liver disease before and after UDCA administration.
Hepatology (Baltimore, Md.) 1990;12(2):322-34.
1990: Nakagawa M; Setchell K D
Bile acid metabolism in early life: studies of amniotic fluid.
Journal of lipid research 1990;31(6):1089-98.
1989: Barbuch R J; Coutant J E; Welsh M B; Setchell K D
The use of thermospray liquid chromatography/tandem mass spectrometry for the class identification and structural verification of phytoestrogens in soy protein preparations.
Biomedical & environmental mass spectrometry 1989;18(11):973-7.
1989: Setchell K D; Vestal C H
Thermospray ionization liquid chromatography-mass spectrometry: a new and highly specific technique for the analysis of bile acids.
Journal of lipid research 1989;30(9):1459-69.
1989: Dumaswala R; Setchell K D; Zimmer-Nechemias L; Iida T; Goto J; Nambara T
Identification of 3 alpha,4 beta,7 alpha-trihydroxy-5 beta-cholanoic acid in human bile: reflection of a new pathway in bile acid metabolism in humans.
Journal of lipid research 1989;30(6):847-56.
1988: Setchell K D; Suchy F J; Welsh M B; Zimmer-Nechemias L; Heubi J; Balistreri W F
Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesis.
The Journal of clinical investigation 1988;82(6):2148-57.
1988: Setchell K D; Dumaswala R; Colombo C; Ronchi M
Hepatic bile acid metabolism during early development revealed from the analysis of human fetal gallbladder bile.
The Journal of biological chemistry 1988;263(32):16637-44.
1988: Gosselin S J; Loudy D L; Tarr M J; Balistreri W F; Setchell K D; Johnston J O; Kramer L W; Dresser B L
Veno-occlusive disease of the liver in captive cheetah.
Veterinary pathology 1988;25(1):48-57.
1987: Setchell K D; Gosselin S J; Welsh M B; Johnston J O; Balistreri W F; Kramer L W; Dresser B L; Tarr M J
Dietary estrogens--a probable cause of infertility and liver disease in captive cheetahs.
Gastroenterology 1987;93(2):225-33.
1987: Setchell K D; Welsh M B; Lim C K
High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical and thermospray mass spectrometric detection.
Journal of chromatography 1987;386():315-23.
1987: Setchell K D; Welsh M B; Klooster M J; Balistreri W F; Lim C K
Rapid high-performance liquid chromatography assay for salivary and serum caffeine following an oral load. An indicator of liver function.
Journal of chromatography 1987;385():267-74.

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