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Alessandro Sette

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TOP 3
Bianca R Mothé; A Michelle English; Ilka Hoof; Donald F Hunt; Jeffrey Shabanowitz; John Sidney; Scott Southwood; Amanda Wriston; Alessandro Sette
Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles.
Denise M McKinney; Carla Oseroff; Bjoern Peters; Veronique Schulten; Thomas J Scriba; Rafeul Alam; Cecilia S Lindestam Arlehamn; David Broide; Willem A Hanekom; Denise Hinz; John Sidney; Scott Southwood; Randy Taplitz; Robert Wood; Alessandro Sette
A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population.
Boris Engels; David M Kranz; Rebecca B Liu; Stephen C Meredith; Donald A Rowley; David C Binder; Victor H Engelhard; Alessandro Sette; John Sidney; Hans Schreiber
Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.

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2013: Bianca R Mothé; A Michelle English; Ilka Hoof; Donald F Hunt; Jeffrey Shabanowitz; John Sidney; Scott Southwood; Amanda Wriston; Alessandro Sette
Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles.
Immunogenetics 2013;65(5):371-86.
2013: Denise M McKinney; Carla Oseroff; Bjoern Peters; Veronique Schulten; Thomas J Scriba; Rafeul Alam; Cecilia S Lindestam Arlehamn; David Broide; Willem A Hanekom; Denise Hinz; John Sidney; Scott Southwood; Randy Taplitz; Robert Wood; Alessandro Sette
A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population.
Immunogenetics 2013;65(5):357-70.
2013: Boris Engels; David M Kranz; Rebecca B Liu; Stephen C Meredith; Donald A Rowley; David C Binder; Victor H Engelhard; Alessandro Sette; John Sidney; Hans Schreiber
Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.
Cancer cell 2013;23(4):516-26.
2013: Véronique Schulten; Alessandro Sette; John Sidney; Fatima Ferreira; Rapheul Alam; David H Broide; Fatima Ferreira-Briza; Jason A Greenbaum; Howard M Grey; Michael Hauser; Ravi Kolla; Cecilia S Lindestam Arlehamn; Denise M McKinney; Carla Oseroff; Bjoern Peters
Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(9):3459-64.
2013: John Sidney; Scott Southwood; Howard M Grey; Carrie Moore; Carla Oseroff; Clemencia Pinilla; Alessandro Sette
Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2013;Chapter 18():Unit 18.3..
2013: Gianfranco Mamone; Giuseppe Mazzarella; Alessandro Sette; John Sidney; Riccardo Troncone; Francesco Addeo; Salvatore Auricchio; Alessandra Camarca; Olga Fierro; Carmen Gianfrani
Immunogenic peptides can be detected in whole gluten by transamidating highly susceptible glutamine residues: implication in the search for gluten-free cereals.
Journal of agricultural and food chemistry 2013;61(3):747-54.
2013: Andréa Barbosa de Melo; Rafael Dhalia; Ulisses Braga-Neto; Silvia M L Montenegro; Eduardo J M Nascimento; Mathias Oelke; Jonathan P Schneck; Alessandro Sette; John Sidney; Ana Maria Silva; Ernesto Marques
T-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple HLA-I and -II binding motifs.
PLoS neglected tropical diseases 2013;7(1):e1938.
2013: Cecilia S Lindestam Arlehamn; Denise M McKinney; Federico Mele; Bjoern Peters; Federica Sallusto; Anna Gerasimova; Jason A Greenbaum; Howard Grey; Ryan Henderson; Eddie A James; Yohan Kim; William W Kwok; John Sidney; Justine Swann; Randy Taplitz; Alessandro Sette
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS pathogens 2013;9(1):e1003130.
2013: Yohan Kim; Alessandro Sette; Jonathan W Yewdell; Bjoern Peters
Positional bias of MHC class I restricted T-cell epitopes in viral antigens is likely due to a bias in conservation.
PLoS computational biology 2013;9(1):e1002884.
2013: Véronique Schulten; Pandurangan Vijayanand; Rafeul Alam; David Broide; Carla Oseroff; Bjoern Peters; Alessandro Sette
The identification of potentially pathogenic and therapeutic epitopes from common human allergens.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2013;110(1):7-10.
2012: Nima Salimi; Ward Fleri; Bjoern Peters; Alessandro Sette
The immune epitope database: a historical retrospective of the first decade.
Immunology 2012;137(2):117-23.
2012: Carla Oseroff; Bjoern Peters; Federica Sallusto; Rafeul Alam; Tess M Brodie; David H Broide; Jason A Greenbaum; Howard Grey; Ravi Kolla; Denise M McKinney; John Sidney; Scott Southwood; Victoria Tripple; Randi Vita; Alessandro Sette
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):1800-11.
2012: Carla Oseroff; Bjoern Peters; Anna Pomés; David H Broide; Jason Greenbaum; Howard Grey; Ravi Kolla; John Sidney; Victoria Tripple; Robert A Wood; Alessandro Sette
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):679-88.
2012: Yohan Kim; Ole Lund; Claus Lundegaard; Morten Nielsen; Julia V Ponomarenko; Alessandro Sette; Dorjee Tamang; Peng Wang; Zhanyang Zhu; Philip Bourne; Jason Greenbaum; Bjoern Peters
Immune epitope database analysis resource.
Nucleic acids research 2012;40(Web Server issue):W525-30.
2012: Alessandro Sette; John Sidney; Scott Southwood; David Watkins; Nancy A Wilson; Jessica Berry; Kate Bradley; Courtney Dow; William H Hildebrand; Ilka Hoof; Mark G Lewis; Curtis P McMurtrey; Carrie Moore; Bianca R Mothé
A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules.
Immunogenetics 2012;64(6):421-34.
2012: Carrie Moore; Bianca R Mothé; Kate Bradley; A Michelle English; Donald F Hunt; Bernard A P Lafont; Jeffrey Shabanowitz; John Sidney; Scott Southwood; Amanda Wriston; Alessandro Sette
Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301).
Immunogenetics 2012;64(6):461-8.
2012: Kelly P Burke; Jordana Levine; Lin Liu; Supriya Munshaw; William O Osburn; Stuart C Ray; Alessandro Sette; John Sidney; Andrea L Cox
Immunogenicity and cross-reactivity of a representative ancestral sequence in hepatitis C virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):5177-88.
2012: Cecilia S Lindestam Arlehamn; John Sidney; Randy Taplitz; Rhea N Coler; Jason A Greenbaum; Howard Grey; Ryan Henderson; Eddie A James; William W Kwok; Denise M McKinney; Magdalini Moutaftsi; Daniel Park; Bjoern Peters; Alessandro Sette
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):5020-31.
2012: Karin Schreiber; Alessandro Sette; John Sidney; Michael T Spiotto; Ralph R Weichselbaum; Ainhoa Arina; Boris Engels; Theodore G Karrison; Donald A Rowley; Hans Schreiber
Spleen cells from young but not old immunized mice eradicate large established cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(9):2526-33.
2012: Kerrie Vaughan; Yohan Kim; Alessandro Sette
A comparison of epitope repertoires associated with myasthenia gravis in humans and nonhuman hosts.
Autoimmune diseases 2012;2012():403915.
2012: Anthony P Cannella; Philip L Felgner; Eduardo Gotuzzo; Li Liang; Mayuko Saito; Alessandro Sette; Renée M Tsolis; Joseph M Vinetz
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development.
Frontiers in cellular and infection microbiology 2012;2():1.
2012: Matt Maybeno; Bjoern Peters; Anke Redeker; Stephen P Schoenberger; Alessandro Sette; Suzanne P M Welten; Scott M Loughhead; Ramon Arens
Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella.
PloS one 2012;7(8):e43481.
2012: Yohan Kim; Mansun Law; Bjoern Peters; Jason Greenbaum; Kerrie Vaughan; Alessandro Sette
A meta-analysis of the existing knowledge of immunoreactivity against hepatitis C virus (HCV).
PloS one 2012;7(5):e38028.
2012: Kerry Laing; Alessandro Sette; J Sidney; L Dong; D M Koelle
Immunology in the Clinic Review Series; focus on host responses: T cell responses to herpes simplex viruses.
Clinical and experimental immunology 2012;167(1):47-58.
2011: Jason S Reed; RA Rudersdorf; Alessandro Sette; John Sidney; Andrew D Walsh; David Ian Watkins; Wilfried Bardet; Benjamin J Burwitz; Christopher M Eernisse; Jessica Furlott; Chrystal E Glidden; William H Hildebrand; Holly L Kolar; Enrique J León; Nicholas J Maness; Curtis P McMurtrey; David O'Connor; Shari M Piaskowski; Nancy A Wilson
The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infection.
Immunogenetics 2011;63(12):789-807.
2011: Daniela Weiskopf; Lauren E Yauch; Sujan Shresta; John Sidney; Michael A Angelo; Aruna D De Silva; Aravinda M de Silva; Jason A Greenbaum; Howard Grey; Daisy V John; Ravi V Kolla; Bjoern Peters; Alessandro Sette
Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4268-79.
2011: Christoph Neumann-Haefelin; Katja Nitschke; Cesar Oniangue-Ndza; Karen A Power; Laura L Reyor; Julia Schmidt; Alessandro Sette; John Sidney; Robert Thimme; Marco Binder; Stéphane Bressanelli; Célia Caillet-Saguy; Matthew R Henn; Kelsey Hills-Evans; Susan Ingber; Michael W Kemper; Nadine Kersting; Arthur Y Kim; Thomas Kuntzen; Georg M Lauer; Volker Lohmann; Todd M Allen
Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations.
Hepatology (Baltimore, Md.) 2011;54(4):1157-66.
2011: Christoph T Berger; Jason M Brenchley; Daniel C Douek; Nicole Frahm; Musie Ghebremichael; Kari L Hartman; Leah M Henry; Daniel E Kaufmann; Beatriz Mothe; Florencia Pereyra; David A Price; Laura E Ruff; Alessandro Sette; John Sidney; Vanessa Venturi; Bruce D Walker; Christian Brander
High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control.
Journal of virology 2011;85(18):9334-45.
2011: Shahram Salek-Ardakani; Alessandro Sette; Magdalini Moutaftsi; Michael Croft
Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection.
Journal of virology 2011;85(17):9051-9.
2011: Jason Greenbaum; John Sidney; Jolan Chung; Christian Brander; Bjoern Peters; Alessandro Sette
Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes.
Immunogenetics 2011;63(6):325-35.
2011: Scott Southwood; Christopher Solomon; Ilka Hoof; Richard Rudersdorf; John Sidney; Bjoern Peters; Angela Wahl; Oriana Hawkins; William Hildebrand; Bianca R Mothé; Alessandro Sette
Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities.
Immunogenetics 2011;63(5):275-90.
2011: Hua Cong; Ernest J Mui; William H Witola; John Sidney; Jeff Alexander; Alessandro Sette; Ajesh Maewal; Rima McLeod
Towards an immunosense vaccine to prevent toxoplasmosis: protective Toxoplasma gondii epitopes restricted by HLA-A*0201.
Vaccine 2011;29(4):754-62.
2011: Emily Seymour; Alessandro Sette; Rohini Damle; Bjoern Peters
Cost sensitive hierarchical document classification to triage PubMed abstracts for manual curation.
BMC bioinformatics 2011;12():482.
2011: Peng Wang; Alessandro Sette; John Sidney; Bjoern Peters
A computational pipeline to generate MHC binding motifs.
Immunome research 2011;7(2):3.
2011: Randi Vita; Laura Zarebski; Emily Seymour; Christoph Steinbeck; Steve Turner; Paula de Matos; Marcus Ennis; Zara Josephs; Bjoern Peters; Alessandro Sette
A Model for Collaborative Curation, The IEDB and ChEBI Curation of Non-peptidic Epitopes.
Immunome research 2011;7(1):1-8.
2011: Julia V Ponomarenko; Nikitas Papangelopoulos; Dirk M Zajonc; Bjoern Peters; Alessandro Sette; Philip Bourne
IEDB-3D: structural data within the immune epitope database.
Nucleic acids research 2011;39(Database issue):D1164-70.
2010: Lauren E Yauch; Tyler R Prestwood; Monica M May; Malika M Morar; Raphaël M Zellweger; Bjoern Peters; Alessandro Sette; Sujan Shresta
CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5405-16.
2010: Alessandro Sette; Rino Rappuoli
Reverse vaccinology: developing vaccines in the era of genomics.
Immunity 2010;33(4):530-41.
2010: John Sidney; Amiyah Steen; Carrie Moore; Sandy Ngo; Jolan Chung; Bjoern Peters; Alessandro Sette
Divergent motifs but overlapping binding repertoires of six HLA-DQ molecules frequently expressed in the worldwide human population.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):4189-98.
2010: Jason Botten; J Lindsay Whitton; Polly Barrowman; John Sidney; Jason K Whitmire; Jeff Alexander; Maya F Kotturi; Alessandro Sette; Michael J Buchmeier
A multivalent vaccination strategy for the prevention of Old World arenavirus infection in humans.
Journal of virology 2010;84(19):9947-56.
2010: Carla Oseroff; John Sidney; Maya F Kotturi; Ravi Kolla; Rafeul Alam; David H Broide; Stephen I Wasserman; Daniela Weiskopf; Denise M McKinney; Jo L Chung; Arnd Petersen; Howard Grey; Bjoern Peters; Alessandro Sette
Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(2):943-55.
2010: Christopher Solomon; Scott Southwood; Ilka Hoof; Richard Rudersdorf; Bjoern Peters; John Sidney; Clemencia Pinilla; Maria Cecilia Garibaldi Marcondes; Binhua Ling; Preston Marx; Alessandro Sette; Bianca R Mothé
The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype.
Immunogenetics 2010;62(7):451-64.
2010: Jason Botten; John Sidney; Bianca R Mothé; Bjoern Peters; Alessandro Sette; Maya F Kotturi
Coverage of related pathogenic species by multivalent and cross-protective vaccine design: arenaviruses as a model system.
Microbiology and molecular biology reviews : MMBR 2010;74(2):157-70.
2010: Tze Guan Tan; Ernest J Mui; Hua Cong; William H Witola; Alexandre Montpetit; Stephen P Muench; John Sidney; Jeff Alexander; Alessandro Sette; Michael E Grigg; Ajesh Maewal; Rima McLeod
Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans.
Vaccine 2010;28(23):3977-89.
2010: Jeff Alexander; Pamuk Bilsel; Marie-France del Guercio; Aleksandra Marinkovic-Petrovic; Scott Southwood; Stephani Stewart; Glenn Ishioka; Maya F Kotturi; Jason Botten; John Sidney; Mark Newman; Alessandro Sette
Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus.
Human immunology 2010;71(5):468-74.
2010: Nima Salimi; Ward Fleri; Bjoern Peters; Alessandro Sette
Design and utilization of epitope-based databases and predictive tools.
Immunogenetics 2010;62(4):185-96.
2010: John Sidney; Amiyah Steen; Carrie Moore; Sandy Ngo; Jolan Chung; Bjoern Peters; Alessandro Sette
Five HLA-DP molecules frequently expressed in the worldwide human population share a common HLA supertypic binding specificity.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2492-503.
2010: Kerrie Vaughan; Jason Greenbaum; Yohan Kim; Randi Vita; Jo Chung; Bjoern Peters; David Broide; Richard Goodman; Howard Grey; Alessandro Sette
Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data.
Journal of allergy 2010;2010():628026.
2010: Hua Cong; Ernest J Mui; William H Witola; John Sidney; Jeff Alexander; Alessandro Sette; Ajesh Maewal; Rima McLeod
Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii.
Immunome research 2010;6():12.
2010: Peng Wang; John Sidney; Yohan Kim; Alessandro Sette; Ole Lund; Morten Nielsen; Bjoern Peters
Peptide binding predictions for HLA DR, DP and DQ molecules.
BMC bioinformatics 2010;11():568.
2010: Jo L Chung; Jian Sun; John Sidney; Alessandro Sette; Bjoern Peters
IMMUNOCAT-a data management system for epitope mapping studies.
Journal of biomedicine & biotechnology 2010;2010():856842.
2010: Maya F Kotturi; Jason Botten; Matt Maybeno; John Sidney; Jean Glenn; Huynh-Hoa Bui; Carla Oseroff; Shane Crotty; Bjoern Peters; Howard Grey; Daniel M Altmann; Michael J Buchmeier; Alessandro Sette
Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.
Immunome research 2010;6():4.
2010: Jason A Greenbaum; Erika Assarsson; Jo L Chung; Steven R Head; Alessandro Sette; Bjoern Peters
TiArA: a virtual appliance for the analysis of Tiling Array data.
PloS one 2010;5(4):e9993.
2010: Hao Zhang; Peng Wang; Nikitas Papangelopoulos; Ying Xu; Alessandro Sette; Philip E Bourne; Ole Lund; Julia Ponomarenko; Morten Nielsen; Bjoern Peters
Limitations of Ab initio predictions of peptide binding to MHC class II molecules.
PloS one 2010;5(2):e9272.
2010: Randi Vita; Laura Zarebski; Jason A Greenbaum; Hussein Emami; Ilka Hoof; Nima Salimi; Rohini Damle; Alessandro Sette; Bjoern Peters
The immune epitope database 2.0.
Nucleic acids research 2010;38(Database issue):D854-62.
2009: Alessandro Sette; Howard Grey; Carla Oseroff; Bjoern Peters; Magdalini Moutaftsi; Shane Crotty; Erika Assarsson; Jay Greenbaum; Yohan Kim; Ravi Kolla; David Tscharke; David Koelle; R Paul Johnson; Janice Blum; Steven Head; John Sidney
Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens.
Vaccine 2009;27 Suppl 6():G21-6.
2009: Juan E Moyron-Quiroz; Megan M McCausland; Robin Kageyama; Alessandro Sette; Shane Crotty
The smallpox vaccine induces an early neutralizing IgM response.
Vaccine 2009;28(1):140-7.
2009: Maya F Kotturi; Jason Botten; John Sidney; Huynh-Hoa Bui; Lori Giancola; Matt Maybeno; Josie Babin; Carla Oseroff; Valerie Pasquetto; Jason A Greenbaum; Bjoern Peters; Joey Ting; Danh Do; Lo Vang; Jeff Alexander; Howard Grey; Michael J Buchmeier; Alessandro Sette
A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.
PLoS pathogens 2009;5(12):e1000695.
2009: Jason A Greenbaum; Maya F Kotturi; Yohan Kim; Carla Oseroff; Kerrie Vaughan; Nima Salimi; Randi Vita; Julia V Ponomarenko; Richard H Scheuermann; Alessandro Sette; Bjoern Peters
Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(48):20365-70.
2009: Stephen R Walsh; Jacqueline Gillis; Björn Peters; Bianca R Mothé; John Sidney; Alessandro Sette; R Paul Johnson
Diverse recognition of conserved orthopoxvirus CD8+ T cell epitopes in vaccinated rhesus macaques.
Vaccine 2009;27(36):4990-5000.
2009: John T Loffredo; John Sidney; Alexander T Bean; Dominic Beal; Wilfried Bardet; Angela Wahl; Oriana E Hawkins; Shari M Piaskowski; Nancy A Wilson; William H Hildebrand; David Ian Watkins; Alessandro Sette
Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7763-75.
2009: William J Muller; Lichun Dong; Adrian Vilalta; Benjamin Byrd; Kai M Wilhelm; Christopher L McClurkan; Michal Margalith; Chao Liu; David Kaslow; John Sidney; Alessandro Sette; David M Koelle
Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection.
The Journal of general virology 2009;90(Pt 5):1153-63.
2009: Lauren E Yauch; Raphaël M Zellweger; Maya F Kotturi; Afrina Qutubuddin; John Sidney; Bjoern Peters; Tyler R Prestwood; Alessandro Sette; Sujan Shresta
A protective role for dengue virus-specific CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4865-73.
2009: Magdalini Moutaftsi; Shahram Salek-Ardakani; Michael Croft; Bjoern Peters; John Sidney; Howard Grey; Alessandro Sette
Correlates of protection efficacy induced by vaccinia virus-specific CD8+ T-cell epitopes in the murine intranasal challenge model.
European journal of immunology 2009;39(3):717-22.
2009: Yohan Kim; John Sidney; Clemencia Pinilla; Alessandro Sette; Bjoern Peters
Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior.
BMC bioinformatics 2009;10():394.
2009: Vince Davies; Kerrie Vaughan; Rohini Damle; Bjoern Peters; Alessandro Sette
Classification of the universe of immune epitope literature: representation and knowledge gaps.
PloS one 2009;4(9):e6948.
2009: Maya F Kotturi; Erika Assarsson; Bjoern Peters; Howard Grey; Carla Oseroff; Valerie Pasquetto; Alessandro Sette
Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
Immunome research 2009;5():3.
2009: Ilka Hoof; Bjoern Peters; John Sidney; Lasse Eggers Pedersen; Alessandro Sette; Ole Lund; Soren Buus; Morten Nielsen
NetMHCpan, a method for MHC class I binding prediction beyond humans.
Immunogenetics 2009;61(1):1-13.
2008: Alleluiah Rutebemberwa; Stuart C Ray; Jacquie Astemborski; Jordana Levine; Lin Liu; Kimberly A Dowd; Shalyn Clute; Changyu Wang; Alan Korman; Alessandro Sette; John Sidney; Drew M Pardoll; Andrea L Cox
High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8215-25.
2008: Shahram Salek-Ardakani; Magdalini Moutaftsi; Shane Crotty; Alessandro Sette; Michael Croft
OX40 drives protective vaccinia virus-specific CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7969-76.
2008: Erika Assarsson; Huynh-Hoa Bui; John Sidney; Qing Zhang; Jean Glenn; Carla Oseroff; Innocent N Mbawuike; Jeff Alexander; Mark J Newman; Howard Grey; Alessandro Sette
Immunomic analysis of the repertoire of T-cell specificities for influenza A virus in humans.
Journal of virology 2008;82(24):12241-51.
2008: Courtney Dow; Carla Oseroff; Bjoern Peters; Courtney Nance-Sotelo; John Sidney; Michael J Buchmeier; Alessandro Sette; Bianca R Mothé
Lymphocytic choriomeningitis virus infection yields overlapping CD4+ and CD8+ T-cell responses.
Journal of virology 2008;82(23):11734-41.
2008: Min Kim; Janette Taylor; John Sidney; Z Mikloska; NJ Bodsworth; Katerina Lagios; Heather Dunckley; Karen Byth-Wilson; Martine Denis; Robert Finlayson; Rajiv Khanna; Alessandro Sette; Anthony L Cunningham
Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6604-15.
2008: Matthias Wölfl; Alleluiah Rutebemberwa; Timothy Mosbruger; Qing Mao; Hong-mei Li; Dale Netski; Stuart C Ray; Drew M Pardoll; John Sidney; Alessandro Sette; Todd Allen; Thomas Kuntzen; Daniel G Kavanagh; Jürgen Kuball; Philip D Greenberg; Andrea L Cox
Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6435-46.
2008: R Vita; Bjoern Peters; Alessandro Sette
The curation guidelines of the immune epitope database and analysis resource.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):1066-70.
2008: Milton Jr. Maciel; SRINIVASAN KELLATHUR; Priya R Chikhlikar; Rafael Dhalia; John Sidney; Alessandro Sette; Thomas J August; Ernesto Marques
Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB/c (H2d) mice model.
Virology 2008;378(1):105-17.
2008: Maya F Kotturi; Iain Scott; Tom Wolfe; Bjoern Peters; John Sidney; Hilde Cheroutre; Matthias G von Herrath; Michael J Buchmeier; Howard Grey; Alessandro Sette
Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):2124-33.
2008: Qing Zhang; Peng Wang; Yohan Kim; Pernille Haste-Andersen; John Beaver; Philip Bourne; Huynh-Hoa Bui; Soren Buus; Sune Frankild; Jason Greenbaum; Ole Lund; Claus Lundegaard; Morten Nielsen; Julia V Ponomarenko; Alessandro Sette; Zhanyang Zhu; Bjoern Peters
Immune epitope database analysis resource (IEDB-AR).
Nucleic acids research 2008;36(Web Server issue):W513-8.
2008: Joel D Ernst; David M Lewinsohn; Samuel Behar; Martin Blythe; Larry S Schlesinger; Hardy Kornfeld; Alessandro Sette
Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database.
Tuberculosis (Edinburgh, Scotland) 2008;88(4):366-70.
2008: Alessandro Sette; Magdalini Moutaftsi; Juan Moyron-Quiroz; Megan M McCausland; D Huw Davies; Robert J Johnston; Bjoern Peters; Mohammed Rafii-El-Idrissi Benhnia; Julia Hoffmann; Hua-Poo Su; Kavita Singh; David N Garboczi; Steven Head; Howard Grey; Philip L Felgner; Shane Crotty
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.
Immunity 2008;28(6):847-58.
2008: Carla Oseroff; Bjoern Peters; Valerie Pasquetto; Magdalini Moutaftsi; John Sidney; Vijay Panchanathan; David C Tscharke; Bernard Maillere; Howard Grey; Alessandro Sette
Dissociation between epitope hierarchy and immunoprevalence in CD8 responses to vaccinia virus western reserve.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7193-202.
2008: Nicholas J Maness; Levi J Yant; Chungwon Chung; John T Loffredo; Thomas C Friedrich; Shari M Piaskowski; Jessica Furlott; Gemma E May; Taeko Soma; Enrique J León; Nancy A Wilson; Helen Piontkivska; Austin Hughes; John Sidney; Alessandro Sette; David Ian Watkins
Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques.
Journal of virology 2008;82(11):5245-54.
2008: Arne Schneidewind; Mark Alan Brockman; John Sidney; Yaoyu E Wang; Huabiao Chen; Todd J Suscovich; Bin Li; Rahma I Adam; Rachel L Allgaier; Bianca R Mothé; Thomas Kuntzen; Cesar Oniangue-Ndza; Alicja Trocha; Xu G Yu; Christian Brander; Alessandro Sette; Bruce D Walker; Todd M Allen
Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.
Journal of virology 2008;82(11):5594-605.
2008: Ramon Arens; Peng Wang; John Sidney; Andrea Loewendorf; Alessandro Sette; Stephen P Schoenberger; Bjoern Peters; Chris A Benedict
Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6472-6.
2008: Giuseppe Mazzarella; Rosita Stefanile; Alessandra Camarca; Paolo Giliberti; Elena Cosentini; Caterina Marano; Gaetano Iaquinto; Nicola Giardullo; Salvatore Auricchio; Alessandro Sette; Riccardo Troncone; Carmen Gianfrani
Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis.
Gastroenterology 2008;134(4):1017-27.
2008: Peng Wang; John Sidney; Courtney Dow; Bianca R Mothé; Alessandro Sette; Bjoern Peters
A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach.
PLoS computational biology 2008;4(4):e1000048.
2008: Mohammed Rafii-El-Idrissi Benhnia; Megan M McCausland; Hua-Poo Su; Kavita Singh; Julia Hoffmann; D Huw Davies; Philip L Felgner; Steven Head; Alessandro Sette; David N Garboczi; Shane Crotty
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine.
Journal of virology 2008;82(7):3751-68.
2008: Erika Assarsson; Jason A Greenbaum; Magnus Sundström; Lana Schaffer; Jennifer A Hammond; Valerie Pasquetto; Carla Oseroff; R Curtis Hendrickson; Elliot J Lefkowitz; David C Tscharke; John Sidney; Howard Grey; Steven R Head; Bjoern Peters; Alessandro Sette
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2140-5.
2008: Elin Bergseng; John Sidney; Alessandro Sette; Ludvig M Sollid
Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules.
Human immunology 2008;69(2):94-100.
2008: Laura Zarebski; Kerrie Vaughan; John Sidney; Bjoern Peters; Howard Grey; Kim D Janda; Arturo Casadevall; Alessandro Sette
Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.
Expert review of vaccines 2008;7(1):55-74.
2008: Julia V Ponomarenko; Huynh-Hoa Bui; Wei Li; Nicholas Fusseder; Philip Bourne; Alessandro Sette; Bjoern Peters
ElliPro: a new structure-based tool for the prediction of antibody epitopes.
BMC bioinformatics 2008;9():514.
2008: María G Alvarez; Miriam Postan; D Brent Weatherly; María C Albareda; John Sidney; Alessandro Sette; Carina Olivera; Alejandro H Armenti; Rick L Tarleton; Susana A Laucella
HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.
PLoS neglected tropical diseases 2008;2(9):e288.
2008: Morten Nielsen; Claus Lundegaard; Thomas Blicher; Bjoern Peters; Alessandro Sette; Sune Justesen; Soren Buus; Ole Lund
Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan.
PLoS computational biology 2008;4(7):e1000107.
2008: Anne Burgevin; Loredana Saveanu; Yohan Kim; Emilie Barilleau; Maya Kotturi; Alessandro Sette; Peter van Endert; Bjoern Peters
A detailed analysis of the murine TAP transporter substrate specificity.
PloS one 2008;3(6):e2402.
2008: John Sidney; Erika Assarsson; Carrie Moore; Sandy Ngo; Clemencia Pinilla; Alessandro Sette; Bjoern Peters
Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries.
Immunome research 2008;4():2.
2008: Erik Depla; Annegret Van der Aa; Brian D Livingston; Claire Crimi; Koen Allosery; Veronique De Brabandere; Jonathan Krakover; Sidharta Murthy; Manley Huang; Scott Power; Lilia Babé; Carol Dahlberg; Denise McKinney; Alessandro Sette; Scott Southwood; Ramilla Philip; Mark J Newman; Lydie Meheus
Rational design of a multiepitope vaccine encoding T-lymphocyte epitopes for treatment of chronic hepatitis B virus infections.
Journal of virology 2008;82(1):435-50.
2007: Nicholas J Maness; Laura E Valentine; Gemma E May; Jason Reed; Shari M Piaskowski; Taeko Soma; Jessica Furlott; Eva G Rakasz; Thomas C Friedrich; David A Price; Emma Gostick; Austin Hughes; John Sidney; Alessandro Sette; Nancy A Wilson; David Ian Watkins
AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape.
The Journal of experimental medicine 2007;204(11):2505-12.
2007: Nicole Frahm; Karina Yusim; Todd J Suscovich; Sharon Adams; John Sidney; Peter T Hraber; Hannah S Hewitt; Caitlyn H Linde; Daniel G Kavanagh; Tonia Woodberry; Leah M Henry; Kellie Faircloth; Jennifer Listgarten; Carl Kadie; Nebojsa Jojic; Kaori Sango; Nancy V Brown; Eunice Pae; M Tauheed Zaman; Florian Bihl; Ashok Khatri; Mina John; Simon Mallal; Francesco M Marincola; Bruce D Walker; Alessandro Sette; David Heckerman; Bette T Korber; Christian Brander
Extensive HLA class I allele promiscuity among viral CTL epitopes.
European journal of immunology 2007;37(9):2419-33.
2007: Bianca R Mothé; Barbara S Stewart; Carla Oseroff; Huynh-Hoa Bui; Stephanie Stogiera; Zacarias Garcia; Courtney Dow; Maria P Rodriguez-Carreno; Maya F Kotturi; Valerie Pasquetto; Jason Botten; Shane Crotty; edith janssen; Michael J Buchmeier; Alessandro Sette
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):1058-67.
2007: Erika Assarsson; John Sidney; Carla Oseroff; Valerie Pasquetto; Huynh-Hoa Bui; Nicole Frahm; Christian Brander; Bjoern Peters; Howard Grey; Alessandro Sette
A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7890-901.
2007: Magdalini Moutaftsi; Huynh-Hoa Bui; Bjoern Peters; John Sidney; Shahram Salek-Ardakani; Carla Oseroff; Valerie Pasquetto; Shane Crotty; Michael Croft; Elliot J Lefkowitz; Howard Grey; Alessandro Sette
Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6814-20.
2007: Bjoern Peters; Alessandro Sette
Integrating epitope data into the emerging web of biomedical knowledge resources.
Nature reviews. Immunology 2007;7(6):485-90.
2007: Lichen Jing; Tiana M Chong; Benjamin Byrd; Christopher L McClurkan; Jay Huang; Brian T Story; Karissa M Dunkley; Lydia Aldaz-Carroll; Roselyn J Eisenberg; Gary H Cohen; William W Kwok; Alessandro Sette; David M Koelle
Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6374-86.
2007: Maya F Kotturi; Bjoern Peters; Fernando Buendia-Laysa; John Sidney; Carla Oseroff; Jason Botten; Howard Grey; Michael J Buchmeier; Alessandro Sette
The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus.
Journal of virology 2007;81(10):4928-40.
2007: Jason A Greenbaum; Pernille Haste Andersen; Martin Blythe; Huynh-Hoa Bui; Raul E Cachau; James Crowe; Matthew Davies; A S Kolaskar; Ole Lund; Sherrie Morrison; Brendan Mumey; Yanay Ofran; Jean-Luc Pellequer; Clemencia Pinilla; Julia V Ponomarenko; Gajendra PS Raghava; Marc H V van Regenmortel; Erwin L Roggen; Alessandro Sette; Avner Schlessinger; johannes söllner; Martin Zand; Bjoern Peters
Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools.
Journal of molecular recognition : JMR 2007;20(2):75-82.
2007: Carlota Dobaño; A McTague; Alessandro Sette; Stephen L Hoffman; William O Rogers; Denise L Doolan
Mutating the anchor residues associated with MHC binding inhibits and deviates CD8+ T cell mediated protective immunity against malaria.
Molecular immunology 2007;44(9):2235-48.
2007: Jason Botten; J Lindsay Whitton; Polly Barrowman; John Sidney; Jason K Whitmire; Jeff Alexander; Joey P C Ting; Huynh-Hoa Bui; Alessandro Sette; Michael J Buchmeier
HLA-A2-restricted protection against lethal lymphocytic choriomeningitis.
Journal of virology 2007;81(5):2307-17.
2007: Alessandro Sette; Bjoern Peters
Immune epitope mapping in the post-genomic era: lessons for vaccine development.
Current opinion in immunology 2007;19(1):106-10.
2007: Huynh-Hoa Bui; Bjoern Peters; Erika Assarsson; Innocent N Mbawuike; Alessandro Sette
Ab and T cell epitopes of influenza A virus, knowledge and opportunities.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(1):246-51.
2007: John T Loffredo; Thomas C Friedrich; Enrique J León; Jason J Stephany; Denise S Rodrigues; Sean P Spencer; Alexander T Bean; Dominic Beal; Benjamin J Burwitz; Richard A Rudersdorf; Lyle T Wallace; Shari M Piaskowski; Gemma E May; John Sidney; Emma Gostick; Nancy A Wilson; David A Price; Esper Kallas; Helen Piontkivska; Austin Hughes; Alessandro Sette; David Ian Watkins
CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.
PloS one 2007;2(11):e1152.
2007: Huynh-Hoa Bui; John Sidney; Wei Li; Nicolas Fusseder; Alessandro Sette
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines.
BMC bioinformatics 2007;8():361.
2007: Morten Nielsen; Claus Lundegaard; Thomas Blicher; Kasper Lamberth; Mikkel Harndahl; Sune Justesen; Gustav Røder; Bjoern Peters; Alessandro Sette; Ole Lund; Soren Buus
NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence.
PloS one 2007;2(8):e796.
2007: Huynh-Hoa Bui; Jason Botten; Nicolas Fusseder; Valerie Pasquetto; Bianca R Mothe; Michael J Buchmeier; Alessandro Sette
Protein sequence database for pathogenic arenaviruses.
Immunome research 2007;3():1.
2006: Jason Botten; Jeff Alexander; Valerie Pasquetto; John Sidney; Polly Barrowman; Joey Ting; Bjoern Peters; Scott Southwood; Barbara Stewart; Maria P Rodriguez-Carreno; Bianca R Mothe; J Lindsay Whitton; Alessandro Sette; Michael J Buchmeier
Identification of protective Lassa virus epitopes that are restricted by HLA-A2.
Journal of virology 2006;80(17):8351-61.
2006: John Sidney; Shinichi Asabe; Bjoern Peters; Kelly-Anne Purton; Josan Chung; Timothy J Pencille; Robert Purcell; Christopher M Walker; Francis V Chisari; Alessandro Sette
Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules.
Immunogenetics 2006;58(7):559-70.
2006: Mathias Lichterfeld; Katie L Williams; Stanley K Mui; Shivani S Shah; Bianca R Mothe; Alessandro Sette; Arthur Kim; Mary N Johnston; Nicole C Burgett; Nicole Frahm; Daniel Cohen; Christian Brander; Eric S Rosenberg; Bruce D Walker; Marcus Altfeld; Xu G Yu
T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily.
International immunology 2006;18(7):1179-88.
2006: Magdalini Moutaftsi; Bjoern Peters; Valerie Pasquetto; David C Tscharke; John Sidney; Huynh-Hoa Bui; Howard Grey; Alessandro Sette
A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.
Nature biotechnology 2006;24(7):817-9.
2006: Bjoern Peters; Huynh-Hoa Bui; Sune Frankild; Morten Nielson; Claus Lundegaard; Emrah Kostem; Derek Basch; Kasper Lamberth; Mikkel Harndahl; Ward Fleri; Stephen S Wilson; John Sidney; Ole Lund; Soren Buus; Alessandro Sette
A community resource benchmarking predictions of peptide binding to MHC-I molecules.
PLoS computational biology 2006;2(6):e65.
2006: Florian Bihl; Nicole Frahm; Loriana Di Giammarino; John Sidney; Mina John; Karina Yusim; Tonia Woodberry; Kaori Sango; Hannah S Hewitt; Leah Henry; Caitlyn H Linde; John V Chisholm; Tauheed M Zaman; Eunice Pae; Simon Mallal; Bruce D Walker; Alessandro Sette; Bette T Korber; David Heckerman; Christian Brander
Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4094-101.
2006: Randi Vita; Kerrie Vaughan; Laura Zarebski; Nima Salimi; Ward Fleri; Howard Grey; Muthuraman Sathiamurthy; John Mokili; Huynh-Hoa Bui; Philip Bourne; Julia V Ponomarenko; romulo de castro; Russell K Chan; John Sidney; Stephen S Wilson; Scott Douglas Stewart; Scott Way; Bjoern Peters; Alessandro Sette
Curation of complex, context-dependent immunological data.
BMC bioinformatics 2006;7():341.
2006: Huynh-Hoa Bui; John Sidney; Kenny Dinh; Scott Southwood; Mark J Newman; Alessandro Sette
Predicting population coverage of T-cell epitope-based diagnostics and vaccines.
BMC bioinformatics 2006;7():153.
2005: Caroline L Smith; Mirza Fareed; Valerie Pasquetto; David C Tscharke; Michael J Palmowski; P Rod Dunbar; Alessandro Sette; Adrian L Harris; Vincenzo Cerundolo
Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):8431-7.
2005: John T Loffredo; John Sidney; Shari M Piaskowski; Andrew Szymanski; Jessica Furlott; Richard Rudersdorf; Jason Reed; Bjoern Peters; Heather D Hickman-Miller; Wilfried Bardet; William M Rehrauer; David O'Connor; Nancy A Wilson; William H Hildebrand; Alessandro Sette; David Ian Watkins
The high frequency Indian rhesus macaque MHC class I molecule, Mamu-B*01, does not appear to be involved in CD8+ T lymphocyte responses to SIVmac239.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5986-97.
2005: Bjoern Peters; Huynh-Hoa Bui; John Sidney; Z Weng; John T Loffredo; David Ian Watkins; Bianca R Mothé; Alessandro Sette
A computational resource for the prediction of peptide binding to Indian rhesus macaque MHC class I molecules.
Vaccine 2005;23(45):5212-24.
2005: Valerie Pasquetto; Huynh-Hoa Bui; Rielle Giannino; Cindy Banh; Mirza Fareed; John Sidney; Carla Oseroff; David C Tscharke; Kari Irvine; Jack R Bennink; Bjoern Peters; Scott Southwood; Vincenzo Cerundolo; Howard Grey; jon yewdell; Alessandro Sette
HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):5504-15.
2005: Carla Oseroff; FERDYNAND KOS; Huynh-Hoa Bui; Bjoern Peters; Valerie Pasquetto; Jean Glenn; Tara Palmore; John Sidney; David C Tscharke; Jack R Bennink; Scott Southwood; Howard Grey; jon yewdell; Alessandro Sette
HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13980-5.
2005: Muthuraman Sathiamurthy; Bjoern Peters; Huynh-Hoa Bui; John Sidney; John Mokili; Stephen S Wilson; Ward Fleri; Deborah L McGuinness; Philip Bourne; Alessandro Sette
An ontology for immune epitopes: application to the design of a broad scope database of immune reactivities.
Immunome research 2005;1(1):2.
2005: julian schulze zur wiesch; Georg M Lauer; Cheryl L Day; Arthur Y Kim; Kei Ouchi; Jared E Duncan; Alysse Wurcel; Joerg Timm; Andrea M Jones; Bianca R Mothe; Todd M Allen; Barbara McGovern; Lia L Lewis-Ximenez; John Sidney; Alessandro Sette; Raymond T Chung; Bruce D Walker
Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3603-13.
2005: John Sidney; Scott Southwood; Alessandro Sette
Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires.
Immunogenetics 2005;57(6):393-408.
2005: Bjoern Peters; John Sidney; Phil Bourne; Huynh-Hoa Bui; Soren Buus; Grace Doh; Ward Fleri; Mitch Kronenberg; Ralph Kubo; Ole Lund; David Nemazee; Julia V Ponomarenko; Muthuraman Sathiamurthy; Stephen P Schoenberger; Scott Douglas Stewart; Pamela Surko; Scott Way; Steve Wilson; Alessandro Sette
The design and implementation of the immune epitope database and analysis resource.
Immunogenetics 2005;57(5):326-36.
2005: Huynh-Hoa Bui; John Sidney; Bjoern Peters; Muthuraman Sathiamurthy; Asabe Sinichi; Kelly-Anne Purton; Bianca R Mothé; Francis V Chisari; David Ian Watkins; Alessandro Sette
Automated generation and evaluation of specific MHC binding predictive tools: ARB matrix applications.
Immunogenetics 2005;57(5):304-14.
2005: Marcus Altfeld; Todd M Allen; Elizabeth T Kalife; Nicole Frahm; Marylyn M Addo; Bianca R Mothe; Almas Rathod; Laura L Reyor; Jason Harlow; Xu G Yu; Beth Perkins; Loren K Robinson; John Sidney; Galit Alter; Mathias Lichterfeld; Alessandro Sette; Eric S Rosenberg; Philip J R Goulder; Christian Brander; Bruce D Walker
The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.
Journal of virology 2005;79(8):5000-5.
2005: Alessandro Sette; John Sidney; Huynh-Hoa Bui; Marie-France del Guercio; Jeff Alexander; John T Loffredo; David Ian Watkins; Bianca R Mothé
Characterization of the peptide-binding specificity of Mamu-A*11 results in the identification of SIV-derived epitopes and interspecies cross-reactivity.
Immunogenetics 2005;57(1-2):53-68.
2005: Shabnam Tangri; Bianca R Mothé; Julie Eisenbraun; John Sidney; Scott Southwood; Kristen Briggs; John Zinckgraf; Pamuk Bilsel; Mark Newman; Robert W Chesnut; Cynthia Licalsi; Alessandro Sette
Rationally engineered therapeutic proteins with reduced immunogenicity.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3187-96.
2005: Bjoern Peters; John Sidney; Phil Bourne; Huynh-Hoa Bui; Soren Buus; Grace Doh; Ward Fleri; Mitch Kronenberg; Ralph Kubo; Ole Lund; David Nemazee; Julia V Ponomarenko; Muthuraman Sathiamurthy; Stephen P Schoenberger; Scott Douglas Stewart; Pamela Surko; Scott Way; Steve Wilson; Alessandro Sette
The immune epitope database and analysis resource: from vision to blueprint.
PLoS biology 2005;3(3):e91.
2005: Alessandro Sette; Ward Fleri; Bjoern Peters; Muthuraman Sathiamurthy; Huynh-Hoa Bui; Stephen Wilson
A roadmap for the immunomics of category A-C pathogens.
Immunity 2005;22(2):155-61.
2005: Bjoern Peters; Alessandro Sette
Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method.
BMC bioinformatics 2005;6():132.
2004: John T Loffredo; John Sidney; Christina Wojewoda; Elizabeth J Dodds; Matthew R Reynolds; Gnankang Napoé; Bianca R Mothé; David O'Connor; Nancy A Wilson; David Ian Watkins; Alessandro Sette
Identification of seventeen new simian immunodeficiency virus-derived CD8+ T cell epitopes restricted by the high frequency molecule, Mamu-A*02, and potential escape from CTL recognition.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5064-76.
2004: Denise McKinney; Rhonda Skvoretz; Brian D Livingston; Cara C Wilson; Michelle Anders; Robert W Chesnut; Alessandro Sette; Max Essex; Vladimir Novitsky; Mark J Newman
Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1941-50.
2004: Todd M Allen; Marcus Altfeld; Xu G Yu; Kristin M O'Sullivan; Mathias Lichterfeld; Sylvie Le Gall; Mina John; Bianca R Mothe; Paul K Lee; Elizabeth T Kalife; Daniel E Cohen; Kenneth A Freedberg; Daryld Strick; Mary N Johnston; Alessandro Sette; Eric S Rosenberg; Simon Mallal; Philip J R Goulder; Christian Brander; Bruce D Walker
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.
Journal of virology 2004;78(13):7069-78.
2004: Jeff Alexander; Marie-France del Guercio; Barbara Frame; Ajesh Maewal; Alessandro Sette; Moon H Nahm; Mark J Newman
Development of experimental carbohydrate-conjugate vaccines composed of Streptococcus pneumoniae capsular polysaccharides and the universal helper T-lymphocyte epitope (PADRE).
Vaccine 2004;22(19):2362-7.
2004: Daniel E Kaufmann; Paul M Bailey; John Sidney; Bradford Wagner; Philip J Norris; Mary N Johnston; Lisa A Cosimi; Marylyn M Addo; Mathias Lichterfeld; Marcus Altfeld; Nicole Frahm; Christian Brander; Alessandro Sette; Bruce D Walker; Eric S Rosenberg
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.
Journal of virology 2004;78(9):4463-77.
2004: Silvia Vertuani; Alessandro Sette; John Sidney; Scott Southwood; John Fikes; Elissa Keogh; Jan Alvar Lindencrona; Glenn Ishioka; Jelena Levitskaya; Rolf Kiessling
Improved immunogenicity of an immunodominant epitope of the HER-2/neu protooncogene by alterations of MHC contact residues.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3501-8.
2004: Thomas C Friedrich; Elizabeth J Dodds; Levi J Yant; Lara Vojnov; Richard Rudersdorf; Candice Cullen; David T Evans; Ronald C Desrosiers; Bianca R Mothé; John Sidney; Alessandro Sette; Kevin Kunstman; Steven Wolinsky; Michael Piatak; Jeffrey D Lifson; Austin Hughes; Nancy Wilson; David O'Connor; David Ian Watkins
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Nature medicine 2004;10(3):275-81.
2004: Alessandro Sette
The immune epitope database and analysis resource: from vision to blueprint.
Genome informatics. International Conference on Genome Informatics 2004;15(2):299.
2003: John Sidney; Scott Southwood; Valerie Pasquetto; Alessandro Sette
Simultaneous prediction of binding capacity for multiple molecules of the HLA B44 supertype.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5964-74.
2003: Cara C Wilson; Denise McKinney; Michelle Anders; Samantha MaWhinney; Jeri Forster; Claire Crimi; Scott Southwood; Alessandro Sette; Robert W Chesnut; Mark J Newman; Brian D Livingston
Development of a DNA vaccine designed to induce cytotoxic T lymphocyte responses to multiple conserved epitopes in HIV-1.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5611-23.
2003: Denise L Doolan; Joao C Aguiar; Walter R Weiss; Alessandro Sette; Philip L Felgner; D P Regis; P Quinones-Casas; J R Yates; Peter L Blair; Thomas L Richie; Stephen L Hoffman; Daniel J Carucci
Utilization of genomic sequence information to develop malaria vaccines.
The Journal of experimental biology 2003;206(Pt 21):3789-802.
2003: Robbert van der Most; Kaja Murali-Krishna; J Gibson Lanier; E John Wherry; Maryann T Puglielli; Joseph N Blattman; Alessandro Sette; Rafi Ahmed
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation.
Virology 2003;315(1):93-102.
2003: Denise L Doolan; Scott Southwood; Daniel A Freilich; John Sidney; Norma L Graber; Lori Shatney; Lolita Bebris; Laurence Florens; Carlota Dobano; Adam A Witney; Ettore Appella; Stephen L Hoffman; John R Yates; Daniel J Carucci; Alessandro Sette
Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9952-7.
2003: Alessandro Sette; John Fikes
Epitope-based vaccines: an update on epitope identification, vaccine design and delivery.
Current opinion in immunology 2003;15(4):461-70.
2003: Emanual Maverakis; Jonathan Beech; David B Stevens; Akio Ametani; Laurent Brossay; Peter van den Elzen; Richard Mendoza; Quoc Thai; Luis H Macias; Doug Ethell; Celia W Campagnoni; Anthony T Campagnoni; Alessandro Sette; Eli E Sercarz
Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5342-7.
2003: Alessandro Sette; John Sidney; Brian D Livingston; John Dzuris; Claire Crimi; Christopher M Walker; Scott Southwood; Edward J Collins; Austin Hughes
Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution.
Immunogenetics 2003;54(12):830-41.
2003: Eli Boritz; Brent E Palmer; Brian D Livingston; Alessandro Sette; Cara C Wilson
Diverse repertoire of HIV-1 p24-specific, IFN-gamma-producing CD4+ T cell clones following immune reconstitution on highly active antiretroviral therapy.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):1106-16.
2002: Yutaka Horiguchi; Ikuei Nukaya; Kazuhide Okazawa; Ichiro Kawashima; John Fikes; Alessandro Sette; Masaaki Tachibana; Kazutoh Takesako; Masaru Murai
Screening of HLA-A24-restricted epitope peptides from prostate-specific membrane antigen that induce specific antitumor cytotoxic T lymphocytes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3885-92.
2002: Shabnam Tangri; Cynthia Licalsi; John Sidney; Alessandro Sette
Rationally engineered proteins or antibodies with absent or reduced immunogenicity.
Current medicinal chemistry 2002;9(24):2191-9.
2002: John Sidney; Marie-France del Guercio; Scott Southwood; Alessandro Sette
The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5098-108.
2002: Thorsten U Vogel; Thomas C Friedrich; David O'Connor; William M Rehrauer; Elizabeth J Dodds; Heather D Hickman; William H Hildebrand; John Sidney; Alessandro Sette; Austin Hughes; Helen Horton; Kathy Vielhuber; Richard Rudersdorf; Ivna P De Souza; Matthew R Reynolds; Todd M Allen; Nancy Wilson; David Ian Watkins
Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?
Journal of virology 2002;76(22):11623-36.
2002: Todd M Allen; Peicheng Jing; Briana Calore; Helen Horton; David O'Connor; Tomas Hanke; Marian Piekarczyk; Richard Ruddersdorf; Bianca R Mothé; Carol Emerson; Nancy Wilson; Jeffrey D Lifson; Igor M Belyakov; Jay A Berzofsky; Chenxi Wang; David Allison; David C Montefiori; Ronald C Desrosiers; Steven Wolinsky; Kevin Kunstman; John D Altman; Alessandro Sette; Andrew J McMichael; David Ian Watkins
Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.
Journal of virology 2002;76(20):10507-11.
2002: Kazuhiro Kakimi; Masanori Isogawa; Josan Chung; Alessandro Sette; Francis V Chisari
Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections.
Journal of virology 2002;76(17):8609-20.
2002: Bianca R Mothé; John Sidney; John Dzuris; Max E Liebl; Sarah Fuenger; David Ian Watkins; Alessandro Sette
Characterization of the peptide-binding specificity of Mamu-B*17 and identification of Mamu-B*17-restricted epitopes derived from simian immunodeficiency virus proteins.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):210-9.
2002: Jeff Alexander; Carla Oseroff; Carol Dahlberg; Mingsheng Qin; Glenn Ishioka; Melanie Beebe; John Fikes; Mark Newman; Robert W Chesnut; Phillip A Morton; Kam Fok; Ettore Appella; Alessandro Sette
A decaepitope polypeptide primes for multiple CD8+ IFN-gamma and Th lymphocyte responses: evaluation of multiepitope polypeptides as a mode for vaccine delivery.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6189-98.
2002: Alessandro Sette; Mark Newman; Brian D Livingston; Denise McKinney; John Sidney; Glenn Ishioka; Shabnam Tangri; Jeff Alexander; John Fikes; Robert W Chesnut
Optimizing vaccine design for cellular processing, MHC binding and TCR recognition.
Tissue antigens 2002;59(6):443-51.
2002: Mark J Newman; Brian D Livingston; Denise McKinney; Robert W Chesnut; Alessandro Sette
T-lymphocyte epitope identification and their use in vaccine development for HIV-1.
Frontiers in bioscience : a journal and virtual library 2002;7():d1503-15.
2002: Brian D Livingston; Claire Crimi; Mark Newman; Yuichiro Higashimoto; Ettore Appella; John Sidney; Alessandro Sette
A rational strategy to design multiepitope immunogens based on multiple Th lymphocyte epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5499-506.
2002: Todd M Allen; Lorenzo Mortara; Bianca R Mothé; Max E Liebl; Peicheng Jing; Briana Calore; Marian Piekarczyk; Richard Ruddersdorf; David O'Connor; X Wang; Chenxi Wang; David Allison; John D Altman; Alessandro Sette; Ronald C Desrosiers; Gerd Sutter; David Ian Watkins
Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication.
Journal of virology 2002;76(8):4108-12.
2002: Alessandro Sette; Elissa Keogh; Glenn Ishioka; John Sidney; Shabnam Tangri; Brian D Livingston; Denise McKinney; Mark Newman; Robert W Chesnut; John Fikes
Epitope identification and vaccine design for cancer immunotherapy.
Current opinion in investigational drugs (London, England : 2000) 2002;3(1):132-9.
2001: AL Erickson; Y Kimura; S Igarashi; J Eichelberger; Michael Houghton; John Sidney; Denise McKinney; Alessandro Sette; Austin Hughes; Christopher M Walker
The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.
Immunity 2001;15(6):883-95.
2001: John Sidney; Scott Southwood; Dean L Mann; M A Fernandez-Vina; Mark J Newman; Alessandro Sette
Majority of peptides binding HLA-A*0201 with high affinity crossreact with other A2-supertype molecules.
Human immunology 2001;62(11):1200-16.
2001: John Dzuris; John Sidney; Helen Horton; R Correa; D Carter; Robert W Chesnut; David Ian Watkins; Alessandro Sette
Molecular determinants of peptide binding to two common rhesus macaque major histocompatibility complex class II molecules.
Journal of virology 2001;75(22):10958-68.
2001: Shabnam Tangri; Glenn Ishioka; X Huang; John Sidney; Scott Southwood; John Fikes; Alessandro Sette
Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide.
The Journal of experimental medicine 2001;194(6):833-46.
2001: Brian D Livingston; Mark Newman; Claire Crimi; Denise McKinney; Robert W Chesnut; Alessandro Sette
Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines.
Vaccine 2001;19(32):4652-60.
2001: Alessandro Sette; Brian D Livingston; Denise McKinney; Ettore Appella; John Fikes; John Sidney; Mark Newman; Robert W Chesnut
The development of multi-epitope vaccines: epitope identification, vaccine design and clinical evaluation.
Biologicals : journal of the International Association of Biological Standardization 2001;29(3-4):271-6.
2001: Elissa Keogh; John Fikes; Scott Southwood; E Celis; Robert W Chesnut; Alessandro Sette
Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):787-96.
2001: Christian Brander; P O'Connor; Todd J Suscovich; Norman Jones; Y Lee; Dean H Kedes; Don Ganem; J Martin; Dennis H Osmond; S Southwood; Alessandro Sette; Bruce D Walker; David T Scadden
Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein.
The Journal of infectious diseases 2001;184(2):119-26.
2001: Glenn Ishioka; John Fikes; Mingsheng Qin; C Gianfrani; Robert W Chesnut; Larry E Kahn; Philip R Streeter; Susan L Woulfe; Alessandro Sette
Dendritic cells generated in vivo by a chimeric hematopoietic growth factor, progenipoietin-4, demonstrate potent immunological function.
Vaccine 2001;19(27):3710-9.
2001: Maryann T Puglielli; AJ Zajac; Robbert van der Most; John Dzuris; Alessandro Sette; John D Altman; Rafi Ahmed
In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb.
Journal of virology 2001;75(11):5099-107.
2001: Cara C Wilson; B Palmer; Scott Southwood; John Sidney; Y Higashimoto; Ettore Appella; Robert W Chesnut; Alessandro Sette; Brian D Livingston
Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes.
Journal of virology 2001;75(9):4195-207.
2001: Robert Thimme; KM Chang; Janell Pemberton; Alessandro Sette; Francis V Chisari
Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51.
Journal of virology 2001;75(8):3984-7.
2001: Anita Kumar; Sanjai Kumar; Thong P Le; Scott Southwood; John Sidney; Joe Cohen; Alessandro Sette; Stephen L Hoffman
HLA-A*01-restricted cytotoxic T-lymphocyte epitope from the Plasmodium falciparum circumsporozoite protein.
Infection and immunity 2001;69(4):2766-71.
2001: JA Urvater; Heather D Hickman; John Dzuris; Kiley R Prilliman; Todd M Allen; K J Schwartz; DF Lorentzen; C Shufflebotham; Edward J Collins; Donald L Neiffer; B Raphael; William H Hildebrand; Alessandro Sette; David Ian Watkins
Gorillas with spondyloarthropathies express an MHC class I molecule with only limited sequence similarity to HLA-B27 that binds peptides with arginine at P2.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3334-44.
2001: Marcus Altfeld; Brian D Livingston; N Reshamwala; Phuong Thi Nguyen; Marylyn M Addo; AK Shea; M Newman; John Fikes; John Sidney; PA Wentworth; Robert W Chesnut; Robert L Eldridge; Eric S Rosenberg; Gregory Robbins; Christian Brander; PE Sax; SL Boswell; Theresa Flynn; Susan Buchbinder; Philip J R Goulder; Bruce D Walker; Alessandro Sette; Spyros A Kalams
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif.
Journal of virology 2001;75(3):1301-11.
2001: Alessandro Sette; Carla Oseroff; John Sidney; J Alexander; Robert W Chesnut; Kazuhiro Kakimi; Luca G Guidotti; Francis V Chisari
Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):1389-97.
2001: Hajime Tanaka; Tatsuhiko Tsunoda; Ikuei Nukaya; Alessandro Sette; Kenji Matsuda; Yasukazu Umano; Hiroki Yamaue; Kazutoh Takesako; Hiroshi Tanimura
Mapping the HLA-A24-restricted T-cell epitope peptide from a tumour-associated antigen HER2 / neu: possible immunotherapy for colorectal carcinomas.
British journal of cancer 2001;84(1):94-9.
2001: Todd M Allen; Bianca R Mothé; John Sidney; Peicheng Jing; John Dzuris; Max E Liebl; Thorsten U Vogel; David O'Connor; X Wang; M C Wussow; J A Thomson; John D Altman; David Ian Watkins; Alessandro Sette
CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing.
Journal of virology 2001;75(2):738-49.
2000: John Sidney; John Dzuris; M J Newman; R P Johnson; A Kaur; K Amitinder; C M Walker; E Appella; Bianca R Mothe; David Ian Watkins; Alessandro Sette
Definition of the Mamu A*01 peptide binding specificity: application to the identification of wild-type and optimized ligands from simian immunodeficiency virus regulatory proteins.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6387-99.
2000: Emanual Maverakis; R Mendoza; Scott Southwood; Claudia Raja Gabaglia; Sara R Abromson-Leeman; Anthony T Campagnoni; Alessandro Sette; Eli E Sercarz
Immunogenicity of self antigens is unrelated to MHC-binding affinity: T-cell determinant structure of Golli-MBP in the BALB/c mouse.
Journal of autoimmunity 2000;15(3):315-22.
2000: Denise McKinney; AL Erickson; Christopher M Walker; R Thimme; F V Chisari; John Sidney; Alessandro Sette
Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4414-22.
2000: Victor Levitsky; D Liu; Scott Southwood; Jelena Levitskaya; Alessandro Sette; Maria Masucci
Supermotif peptide binding and degeneracy of MHC: peptide recognition in an EBV peptide-specific CTL response with highly restricted TCR usage.
Human immunology 2000;61(10):972-84.
2000: Todd M Allen; David O'Connor; Peicheng Jing; John Dzuris; Bianca R Mothé; Thorsten U Vogel; E Dunphy; Max E Liebl; C Emerson; Nancy Wilson; Kevin Kunstman; X Wang; David Allison; Austin Hughes; Ronald C Desrosiers; John D Altman; Steven Wolinsky; Alessandro Sette; David Ian Watkins
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
Nature 2000;407(6802):386-90.
2000: David T Evans; Peicheng Jing; Todd M Allen; David O'Connor; Helen Horton; J E Venham; Marian Piekarczyk; John Dzuris; M Dykhuzen; Jacque Mitchen; RA Rudersdorf; C. David Pauza; Alessandro Sette; Ronald E Bontrop; R DeMars; David Ian Watkins
Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression.
Journal of virology 2000;74(16):7400-10.
2000: Denise L Doolan; Scott Southwood; Robert W Chesnut; Ettore Appella; E Gomez; A Richards; Y I Higashimoto; Ajesh Maewal; John Sidney; Robert A Gramzinski; Carl Mason; D Koech; Stephen L Hoffman; Alessandro Sette
HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):1123-37.
2000: Todd M Allen; Thorsten U Vogel; Deborah H Fuller; Bianca R Mothé; SR Steffen; Jonathan Boyson; Tim Shipley; J Fuller; T Hanke; Alessandro Sette; John D Altman; Bernard Moss; A J McMichael; David Ian Watkins
Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4968-78.
2000: C Gianfrani; Carla Oseroff; John Sidney; Robert W Chesnut; Alessandro Sette
Human memory CTL response specific for influenza A virus is broad and multispecific.
Human immunology 2000;61(5):438-52.
2000: Denise McKinney; R Skvoretz; Mingsheng Qin; Glenn Ishioka; Alessandro Sette
Characterization of an in situ IFN-gamma ELISA assay which is able to detect specific peptide responses from freshly isolated splenocytes induced by DNA minigene immunization.
Journal of immunological methods 2000;237(1-2):105-17.
2000: Matthias G von Herrath; DP Berger; Dirk Homann; T Tishon; Alessandro Sette; Michael B A Oldstone
Vaccination to treat persistent viral infection.
Virology 2000;268(2):411-9.
2000: Joyce T Tan; Jason K Whitmire; Kaja Murali-Krishna; Rafi Ahmed; John D Altman; Robert S Mittler; Alessandro Sette; Thomas C Pearson; Christian P Larsen
4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2320-5.
2000: Jeff Alexander; Marie-France del Guercio; Ajesh Maewal; L Qiao; John Fikes; Robert W Chesnut; J Paulson; D R Bundle; S DeFrees; Alessandro Sette
Linear PADRE T helper epitope and carbohydrate B cell epitope conjugates induce specific high titer IgG antibody responses.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1625-33.
2000: John Dzuris; John Sidney; E Appella; Robert W Chesnut; David Ian Watkins; Alessandro Sette
Conserved MHC class I peptide binding motif between humans and rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):283-91.
1999: Alessandro Sette; J Sidney
Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism.
Immunogenetics 1999;50(3-4):201-12.
1999: Brian D Livingston; Claire Crimi; John Fikes; Robert W Chesnut; John Sidney; Alessandro Sette
Immunization with the HBV core 18-27 epitope elicits CTL responses in humans expressing different HLA-A2 supertype molecules.
Human immunology 1999;60(11):1013-7.
1999: David T Evans; David O'Connor; Peicheng Jing; John Dzuris; John Sidney; J da Silva; Todd M Allen; Helen Horton; J E Venham; RA Rudersdorf; T Vogel; C. David Pauza; Ronald E Bontrop; R DeMars; Alessandro Sette; Austin Hughes; David Ian Watkins
Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.
Nature medicine 1999;5(11):1270-6.
1999: Kamal D Moudgil; Scott Southwood; Akio Ametani; K Kim; Alessandro Sette; Eli E Sercarz
The self-directed T cell repertoire against mouse lysozyme reflects the influence of the hierarchy of its own determinants and can be engaged by a foreign lysozyme.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4232-7.
1999: J Gibson Lanier; MJ Newman; E M Lee; Alessandro Sette; Rafi Ahmed
Peptide vaccination using nonionic block copolymers induces protective anti-viral CTL responses.
Vaccine 1999;18(5-6):549-57.
1999: M Furchner; AL Erickson; T Allen; David Ian Watkins; Alessandro Sette; Philip R Johnson; Christopher M Walker
The simian immunodeficiency virus envelope glycoprotein contains two epitopes presented by the Mamu-A*01 class I molecule.
Journal of virology 1999;73(10):8035-9.
1999: Glenn Ishioka; John Fikes; G Hermanson; Brian D Livingston; Claire Crimi; Mingsheng Qin; Marie-France del Guercio; Carla Oseroff; Carol Dahlberg; Jeff Alexander; Robert W Chesnut; Alessandro Sette
Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):3915-25.
1999: E D Franke; Stephen L Hoffman; John B Sacci; Ruobing Wang; Yupin Charoenvit; E Appella; Robert W Chesnut; J Alexander; M F Del Guercio; Alessandro Sette
Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites.
Vaccine 1999;17(9-10):1201-5.
1999: Brian D Livingston; Jeff Alexander; Claire Crimi; Carla Oseroff; E Celis; K Daly; Luca G Guidotti; Francis V Chisari; John Fikes; Robert W Chesnut; Alessandro Sette
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):3088-95.
1999: Ikuo Tsunoda; Alessandro Sette; Robert S Fujinami; Carla Oseroff; J Ruppert; Carol Dahlberg; Scott Southwood; T Arrhenius; Li-Qing Kuang; RT Kubo; Robert W Chesnut; Glenn Ishioka
Lipopeptide particles as the immunologically active component of CTL inducing vaccines.
Vaccine 1999;17(7-8):675-85.
1999: Ichiro Kawashima; V Tsai; Scott Southwood; Kazutoh Takesako; Alessandro Sette; E Celis
Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells.
Cancer research 1999;59(2):431-5.
1999: K M Chang; Norbert H Gruener; Scott Southwood; John Sidney; G R Pape; Francis V Chisari; Alessandro Sette
Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1156-64.
1999: Ikuei Nukaya; M Yasumoto; T Iwasaki; M Ideno; Alessandro Sette; E Celis; Kazutoh Takesako; I Kato
Identification of HLA-A24 epitope peptides of carcinoembryonic antigen which induce tumor-reactive cytotoxic T lymphocyte.
International journal of cancer. Journal international du cancer 1999;80(1):92-7.
1998: Jeff Alexander; Marie-France del Guercio; John Fikes; Robert W Chesnut; Francis V Chisari; K M Chang; Ettore Appella; Alessandro Sette
Recognition of a novel naturally processed, A2 restricted, HCV-NS4 epitope triggers IFN-gamma release in absence of detectable cytopathicity.
Human immunology 1998;59(12):776-82.
1998: Ichiro Kawashima; V Tsai; Scott Southwood; Kazutoh Takesako; E Celis; Alessandro Sette
Identification of gp100-derived, melanoma-specific cytotoxic T-lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells.
International journal of cancer. Journal international du cancer 1998;78(4):518-24.
1998: U Zügel; Rongfang Wang; G Shih; Alessandro Sette; Jeff Alexander; Howard Grey
Termination of peripheral tolerance to a T cell epitope by heteroclitic antigen analogues.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1705-9.
1998: Alessandro Sette; John Sidney
HLA supertypes and supermotifs: a functional perspective on HLA polymorphism.
Current opinion in immunology 1998;10(4):478-82.
1998: David J D Sourdive; Kaja Murali-Krishna; John D Altman; AJ Zajac; Jason K Whitmire; Christophe Pannetier; Philippe Kourilsky; Brian D Evavold; Alessandro Sette; Rafi Ahmed
Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection.
The Journal of experimental medicine 1998;188(1):71-82.
1998: Todd M Allen; John Sidney; M F del Guercio; R L Glickman; Gary L Lensmeyer; D A Wiebe; R DeMars; C. David Pauza; R P Johnson; Alessandro Sette; David Ian Watkins
Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6062-71.
1998: Carla Oseroff; Alessandro Sette; PA Wentworth; E Celis; Ajesh Maewal; Carol Dahlberg; John Fikes; RT Kubo; Robert W Chesnut; Howard Grey; Jeff Alexander
Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses.
Vaccine 1998;16(8):823-33.
1998: Scott Southwood; John Sidney; A Kondo; Marie-France del Guercio; Ettore Appella; S Hoffman; RT Kubo; Robert W Chesnut; Howard Grey; Alessandro Sette
Several common HLA-DR types share largely overlapping peptide binding repertoires.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3363-73.
1998: Robbert van der Most; Kaja Murali-Krishna; J L Whitton; Carla Oseroff; J Alexander; Scott Southwood; John Sidney; Robert W Chesnut; Alessandro Sette; Rafi Ahmed
Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice.
Virology 1998;240(1):158-67.
1998: Ichiro Kawashima; S J Hudson; V Tsai; Scott Southwood; Kazutoh Takesako; Ettore Appella; Alessandro Sette; E Celis
The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors.
Human immunology 1998;59(1):1-14.
1998: V Tsai; Ichiro Kawashima; Elissa Keogh; K Daly; Alessandro Sette; E Celis
In vitro immunization and expansion of antigen-specific cytotoxic T lymphocytes for adoptive immunotherapy using peptide-pulsed dendritic cells.
Critical reviews in immunology 1998;18(1-2):65-75.
1997: Jeff Alexander; Carla Oseroff; John Sidney; PA Wentworth; E Keogh; G Hermanson; Francis V Chisari; RT Kubo; Howard Grey; Alessandro Sette
Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4753-61.
1997: John Sidney; Marie-France del Guercio; Scott Southwood; G Hermanson; Ajesh Maewal; Ettore Appella; Alessandro Sette
The HLA-A*0207 peptide binding repertoire is limited to a subset of the A*0201 repertoire.
Human immunology 1997;58(1):12-20.
1997: KM Chang; B Rehermann; J G McHutchison; C Pasquinelli; Scott Southwood; Alessandro Sette; Francis V Chisari
Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.
The Journal of clinical investigation 1997;100(9):2376-85.
1997: Lindsay B Nicholson; A Murtaza; B P Hafler; Alessandro Sette; Vijay K Kuchroo
A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9279-84.
1997: S C Threlkeld; PA Wentworth; Spyros A Kalams; BM Wilkes; DJ Ruhl; Elissa Keogh; John Sidney; Scott Southwood; Bruce D Walker; Alessandro Sette
Degenerate and promiscuous recognition by CTL of peptides presented by the MHC class I A3-like superfamily: implications for vaccine development.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1648-57.
1997: R Bertoni; J Sidney; P Fowler; R W Chesnut; Francis V Chisari; Alessandro Sette
Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis.
The Journal of clinical investigation 1997;100(3):503-13.
1997: Brian D Livingston; Claire Crimi; Howard Grey; Glenn Ishioka; Francis V Chisari; John Fikes; H Grey; Robert W Chesnut; Alessandro Sette
The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1383-92.
1997: Denise L Doolan; Stephen L Hoffman; Scott Southwood; PA Wentworth; John Sidney; Robert W Chesnut; Elissa Keogh; E Appella; T B Nutman; A A Lal; Daniel M Gordon; James OLOO; Alessandro Sette
Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles.
Immunity 1997;7(1):97-112.
1997: J Kim; Alessandro Sette; S Rodda; Scott Southwood; Peter Allan Sieling; V Mehra; J D Ohmen; J Oliveros; Ettore Appella; Y Higashimoto; Thomas H Rea; Barry R Bloom; Robert L Modlin
Determinants of T cell reactivity to the Mycobacterium leprae GroES homologue.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):335-43.
1997: Robbert van der Most; R J Concepcion; Carla Oseroff; J Alexander; Scott Southwood; John Sidney; Robert W Chesnut; Rafi Ahmed; Alessandro Sette
Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.
Journal of virology 1997;71(7):5110-4.
1997: Marie-France del Guercio; Jeff Alexander; RT Kubo; T Arrhenius; Ajesh Maewal; Ettore Appella; Stephen L Hoffman; T Jones; D Valmori; K Sakaguchi; Howard Grey; Alessandro Sette
Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo.
Vaccine 1997;15(4):441-8.
1997: V Tsai; Scott Southwood; John Sidney; K Sakaguchi; Y Kawakami; Ettore Appella; Alessandro Sette; E Celis
Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1796-802.
1997: A Kondo; John Sidney; Scott Southwood; Marie-France del Guercio; Ettore Appella; H Sakamoto; Howard Grey; E Celis; Robert W Chesnut; RT Kubo; Alessandro Sette
Two distinct HLA-A*0101-specific submotifs illustrate alternative peptide binding modes.
Immunogenetics 1997;45(4):249-58.
1996: Lara J Ausubel; C K Kwan; Alessandro Sette; Vijay K Kuchroo; David A Hafler
Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15317-22.
1996: Antonella Vitiello; L Yuan; Robert W Chesnut; John Sidney; Scott Southwood; P Farness; MR Jackson; PA Peterson; Alessandro Sette
Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5555-62.
1996: Robbert van der Most; Alessandro Sette; Carla Oseroff; J Alexander; Kaja Murali-Krishna; L L Lau; Scott Southwood; John Sidney; Robert W Chesnut; M Matloubian; Rafi Ahmed
Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5543-54.
1996: John Sidney; Scott Southwood; Marie-France del Guercio; Howard Grey; Robert W Chesnut; RT Kubo; Alessandro Sette
Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3480-90.
1996: F di Marzo Veronese; D Arnott; Vincenzo Barnaba; D J Loftus; K Sakaguchi; Craig Thompson; S Salemi; C Mastroianni; Alessandro Sette; J Shabanowitz; D F Hunt; Ettore Appella
Autoreactive cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected subjects.
The Journal of experimental medicine 1996;183(6):2509-16.
1996: PA Wentworth; Alessandro Sette; E Celis; John Sidney; Scott Southwood; Claire Crimi; S Stitely; Elissa Keogh; N C Wong; Brian D Livingston; D Alazard; Antonella Vitiello; Howard Grey; Francis V Chisari; Robert W Chesnut; John Fikes
Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome.
International immunology 1996;8(5):651-9.
1996: M Bocchia; T Korontsvit; Q Xu; S Mackinnon; SY Yang; Alessandro Sette; David A Scheinberg
Specific human cellular immunity to bcr-abl oncogene-derived peptides.
Blood 1996;87(9):3587-92.
1996: John Sidney; Howard Grey; Scott Southwood; E Celis; PA Wentworth; Marie-France del Guercio; RT Kubo; Robert W Chesnut; Alessandro Sette
Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules.
Human immunology 1996;45(2):79-93.
1996: Maaike E Ressing; WJ van Driel; E Celis; Alessandro Sette; M P Brandt; M Hartman; J D Anholts; G M Th Schreuder; W B ter Harmsel; Gert Jan Fleuren; Baptist J Trimbos; W Martin Kast; Cornelis J M Melief
Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.
Cancer research 1996;56(3):582-8.
1996: Judith Greer; Raymond A Sobel; Alessandro Sette; S Southwood; Marjorie B Lees; Vijay K Kuchroo
Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(1):371-9.
1996: PA Wentworth; Antonella Vitiello; John Sidney; Elissa Keogh; Robert W Chesnut; Howard Grey; Alessandro Sette
Differences and similarities in the A2.1-restricted cytotoxic T cell repertoire in humans and human leukocyte antigen-transgenic mice.
European journal of immunology 1996;26(1):97-101.
1995: A Kondo; John Sidney; Scott Southwood; Marie-France del Guercio; Ettore Appella; H Sakamoto; E Celis; Howard Grey; Robert W Chesnut; RT Kubo; Alessandro Sette
Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4307-12.
1995: N K Nanda; K K Arzoo; H M Geysen; Alessandro Sette; Eli E Sercarz
Recognition of multiple peptide cores by a single T cell receptor.
The Journal of experimental medicine 1995;182(2):531-9.
1995: Silva Markovic-Plese; H Fukaura; J Zhang; A al-Sabbagh; S Southwood; Alessandro Sette; Vijay K Kuchroo; David A Hafler
T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):982-92.
1995: Benjamin Wizel; R Houghten; P Church; John A Tine; David Lanar; D M Gordon; W Ripley Ballou; Alessandro Sette; Stephen L Hoffman
HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):766-75.
1995: PA Wentworth; E Celis; Claire Crimi; S Stitely; L Hale; V Tsai; H M Serra; Marie-France del Guercio; Brian D Livingston; D Alazard; John Fikes; RT Kubo; Howard Grey; Robert W Chesnut; Francis V Chisari; Alessandro Sette
In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides.
Molecular immunology 1995;32(9):603-12.
1995: Ram Raj Singh; V Kumar; Fanny M Ebling; Scott Southwood; Alessandro Sette; Eli E Sercarz; Bevra H Hahn
T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus.
The Journal of experimental medicine 1995;181(6):2017-27.
1995: Maaike E Ressing; Alessandro Sette; RM Brandt; J Ruppert; PA Wentworth; M Hartman; Carla Oseroff; Howard Grey; Cornelis J M Melief; W Martin Kast
Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5934-43.
1995: M Bocchia; PA Wentworth; Scott Southwood; John Sidney; K McGraw; David A Scheinberg; Alessandro Sette
Specific binding of leukemia oncogene fusion protein peptides to HLA class I molecules.
Blood 1995;85(10):2680-4.
1995: Per Höllsberg; W E Weber; F Dangond; V Batra; Alessandro Sette; David A Hafler
Differential activation of proliferation and cytotoxicity in human T-cell lymphotropic virus type I Tax-specific CD8 T cells by an altered peptide ligand.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):4036-40.
1995: M Battegay; John Fikes; A M Di Bisceglie; PA Wentworth; Alessandro Sette; E Celis; W M Ching; Arash Grakoui; C M Rice; K Kurokohchi
Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules.
Journal of virology 1995;69(4):2462-70.
1995: A Windhagen; C Scholz; Per Höllsberg; Hikoaki Fukaura; Alessandro Sette; David A Hafler
Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand.
Immunity 1995;2(4):373-80.
1995: B Rehermann; P Fowler; John Sidney; J Person; Allan Redeker; M Brown; Bernard Moss; Alessandro Sette; Francis V Chisari
The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis.
The Journal of experimental medicine 1995;181(3):1047-58.
1995: Marie-France del Guercio; John Sidney; G Hermanson; C Perez; Howard Grey; RT Kubo; Alessandro Sette
Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):685-93.
1995: Jeff Alexander; J Ruppert; Dawne M Page; S M Hedrick; A Franco; Glenn Ishioka; Howard Grey; Alessandro Sette
Antigen analogs as therapeutic agents.
Advances in experimental medicine and biology 1995;386():109-18.
1995: J Ruppert; A Franco; Jeff Alexander; K Snoke; Glenn Ishioka; Dawne M Page; Stephen M Hedrick; L Adorini; Howard Grey; Alessandro Sette
MHC blocking peptides and T-cell receptor antagonists: novel paths to selective immunosuppression?
Chemical immunology 1995;60():61-78.
1995: Robert W Chesnut; Alessandro Sette; E Celis; PA Wentworth; RT Kubo; J Alexander; Glenn Ishioka; Antonella Vitiello; Howard Grey
Design and testing of peptide-based cytotoxic T-cell-mediated immunotherapeutics to treat infectious diseases and cancer.
Pharmaceutical biotechnology 1995;6():847-74.
1995: Howard Grey; J Ruppert; Antonella Vitiello; John Sidney; W Martin Kast; RT Kubo; Alessandro Sette
Class I MHC-peptide interactions: structural requirements and functional implications.
Cancer surveys 1995;22():37-49.
1994: Alessandro Sette; Antonella Vitiello; B Reherman; P Fowler; R Nayersina; W Martin Kast; Cornelis J M Melief; Carla Oseroff; L Yuan; J Ruppert; John Sidney; Marie-France del Guercio; Scott Southwood; RT Kubo; Robert W Chesnut; Howard Grey; Francis V Chisari
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5586-92.
1994: Jeff Alexander; John Sidney; Scott Southwood; J Ruppert; Carla Oseroff; Ajesh Maewal; K Snoke; H M Serra; RT Kubo; Alessandro Sette
Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides.
Immunity 1994;1(9):751-61.
1994: E Celis; John Fikes; PA Wentworth; John Sidney; Scott Southwood; Ajesh Maewal; Marie-France del Guercio; Alessandro Sette; Brian D Livingston
Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles.
Molecular immunology 1994;31(18):1423-30.
1994: Vijay K Kuchroo; Judith Greer; D Kaul; Glenn Ishioka; A Franco; Alessandro Sette; Raymond A Sobel; Marjorie B Lees
A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):3326-36.
1994: Alessandro Sette; John Sidney; Marie-France del Guercio; Scott Southwood; J Ruppert; Carol Dahlberg; Howard Grey; RT Kubo
Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays.
Molecular immunology 1994;31(11):813-22.
1994: J Ruppert; RT Kubo; John Sidney; Howard Grey; Alessandro Sette
Class I MHC-peptide interaction: structural and functional aspects.
Behring Institute Mitteilungen 1994;(94):48-60.
1994: Annemieke Geluk; Krista E van Meijgaarden; Scott Southwood; Carla Oseroff; Jan Wouter Drijfhout; René R P De Vries; Tom H M Ottenhoff; Alessandro Sette
HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):5742-8.
1994: Glenn Ishioka; L Adorini; J C Guery; F C Gaeta; R LaFond; Jeff Alexander; M F Powell; Alessandro Sette; Howard Grey
Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4310-9.
1994: John Sidney; Carla Oseroff; Marie-France del Guercio; Scott Southwood; J I Krieger; Glenn Ishioka; K Sakaguchi; E Appella; Alessandro Sette
Definition of a DQ3.1-specific binding motif.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4516-25.
1994: Dawne M Page; Jeff Alexander; K Snoke; E Appella; Alessandro Sette; Stephen M Hedrick; Howard Grey
Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4057-61.
1994: R T Kubo; Alessandro Sette; Howard Grey; Ettore Appella; K Sakaguchi; N Z Zhu; D Arnott; N Sherman; J Shabanowitz; H Michel
Definition of specific peptide motifs for four major HLA-A alleles.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3913-24.
1994: W Martin Kast; RM Brandt; J Sidney; Jan Wouter Drijfhout; R T Kubo; Howard Grey; Cornelis J M Melief; Alessandro Sette
Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3904-12.
1994: A Franco; Scott Southwood; T Arrhenius; V K Kuchroo; Howard Grey; Alessandro Sette; Glenn Ishioka
T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis.
European journal of immunology 1994;24(4):940-6.
1994: E Celis; V Tsai; Claire Crimi; R DeMars; PA Wentworth; Robert W Chesnut; Howard Grey; Alessandro Sette; H M Serra
Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2105-9.
1994: Jeff Alexander; J Ruppert; K Snoke; Alessandro Sette
TCR antagonism and T cell tolerance can be independently induced in a DR-restricted, hemagglutinin-specific T cell clone.
International immunology 1994;6(3):363-7.
1994: Alessandro Sette; Jeff Alexander; J Ruppert; K Snoke; A Franco; Glenn Ishioka; Howard Grey
Antigen analogs/MHC complexes as specific T cell receptor antagonists.
Annual review of immunology 1994;12():413-31.
1993: K Snoke; J Alexander; A Franco; L Smith; J V Brawley; Patrick Concannon; Howard Grey; Alessandro Sette; PA Wentworth
The inhibition of different T cell lines specific for the same antigen with TCR antagonist peptides.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6815-21.
1993: H M Serra; Claire Crimi; Alessandro Sette; E Celis
Fine restriction analysis and inhibition of antigen recognition in HLA-DQ-restricted T cells by major histocompatibility complex blockers and T cell receptor antagonists.
European journal of immunology 1993;23(11):2967-71.
1993: Alessandro Sette; John Sidney; Carla Oseroff; Marie-France del Guercio; Scott Southwood; T Arrhenius; M F Powell; S M Colón; F C Gaeta; Howard Grey
HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3163-70.
1993: J Ruppert; John Sidney; E Celis; RT Kubo; Howard Grey; Alessandro Sette
Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules.
Cell 1993;74(5):929-37.
1993: M F Powell; T Stewart; Laszlo Otvos; L Urge; F C Gaeta; Alessandro Sette; T Arrhenius; D Thomson; K Soda; S M Colon
Peptide stability in drug development. II. Effect of single amino acid substitution and glycosylation on peptide reactivity in human serum.
Pharmaceutical research 1993;10(9):1268-73.
1993: Alessandro Sette; John Sidney; F C Gaeta; E Appella; S M Colón; Marie-France del Guercio; J C Guéry; L Adorini
MHC class II molecules bind indiscriminately self and non-self peptide homologs: effect on the immunogenicity of non-self peptides.
International immunology 1993;5(6):631-8.
1993: J Ruppert; Jeff Alexander; K Snoke; M Coggeshall; E Herbert; D McKenzie; Howard Grey; Alessandro Sette
Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2671-5.
1993: Howard Grey; Jeff Alexander; K Snoke; Alessandro Sette; J Ruppert
Antigen analogues as antagonists of the T cell receptor.
Clinical and experimental rheumatology 1993;11 Suppl 8():S47-50.
1993: Alessandro Sette; R DeMars; Howard Grey; Carla Oseroff; Scott Southwood; Ettore Appella; RT Kubo; D F Hunt
Isolation and characterization of naturally processed peptides bound by class II molecules and peptides presented by normal and mutant antigen-presenting cells.
Chemical immunology 1993;57():152-65.
1993: Glenn Ishioka; A G Lamont; D Thomson; N Bulbow; F C Gaeta; Alessandro Sette; Howard Grey
Major histocompatibility complex class II association and induction of T cell responses by carbohydrates and glycopeptides.
Springer seminars in immunopathology 1993;15(2-3):293-302.
1992: John Sidney; Carla Oseroff; Scott Southwood; M Wall; Glenn Ishioka; F Koning; Alessandro Sette
DRB1*0301 molecules recognize a structural motif distinct from the one recognized by most DR beta 1 alleles.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2634-40.
1992: M F Powell; Howard Grey; F Gaeta; Alessandro Sette; S Colón
Peptide stability in drug development: a comparison of peptide reactivity in different biological media.
Journal of pharmaceutical sciences 1992;81(8):731-5.
1992: M Wall; Scott Southwood; John Sidney; Carla Oseroff; M F del Guericio; A G Lamont; S M Colón; T Arrhenius; F C Gaeta; Alessandro Sette
High affinity for class II molecules as a necessary but not sufficient characteristic of encephalitogenic determinants.
International immunology 1992;4(7):773-7.
1992: Glenn Ishioka; A G Lamont; D Thomson; N Bulbow; F C Gaeta; Alessandro Sette; Howard Grey
MHC interaction and T cell recognition of carbohydrates and glycopeptides.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2446-51.
1992: M T De Magistris; Jeff Alexander; M Coggeshall; A Altman; F C Gaeta; Howard Grey; Alessandro Sette
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor.
Cell 1992;68(4):625-34.
1992: Alessandro Sette; Scott Southwood; D O'Sullivan; F C Gaeta; John Sidney; Howard Grey
Effect of pH on MHC class II-peptide interactions.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(3):844-51.
1991: Alessandro Sette; Antonella Vitiello; P Farness; J Furze; John Sidney; J M Claverie; Howard Grey; R Chesnut
Random association between the peptide repertoire of A2.1 class I and several different DR class II molecules.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):3893-900.
1991: S Demotz; Alessandro Sette; K Sakaguchi; R Buchner; E Appella; Howard Grey
Self peptide requirement for class II major histocompatibility complex allorecognition.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8730-4.
1991: Alessandro Sette; D O'Sullivan; J I Krieger; R W Karr; A G Lamont; Howard Grey
MHC-antigen-T cell interactions: an overview.
Seminars in immunology 1991;3(4):195-202.
1991: T Pedrazzini; Alessandro Sette; M Albertson; Howard Grey
Free ligand-induced dissociation of MHC-antigen complexes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(10):3496-501.
1991: D O'Sullivan; John Sidney; Marie-France del Guercio; S M Colón; Alessandro Sette
Truncation analysis of several DR binding epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1240-6.
1990: D O'Sullivan; John Sidney; E Appella; L Walker; L Phillips; S M Colón; C Miles; Robert W Chesnut; Alessandro Sette
Characterization of the specificity of peptide binding to four DR haplotypes.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1799-808.
1990: Alessandro Sette; John Sidney; M Albertson; C Miles; S M Colón; T Pedrazzini; A G Lamont; Howard Grey
A novel approach to the generation of high affinity class II-binding peptides.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1809-13.
1990: A G Lamont; Alessandro Sette; R Fujinami; S M Colón; C Miles; Howard Grey
Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1687-93.
1990: A G Lamont; M F Powell; S M Colón; C Miles; Howard Grey; Alessandro Sette
The use of peptide analogs with improved stability and MHC binding capacity to inhibit antigen presentation in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2493-8.
1990: A G Lamont; Alessandro Sette; Howard Grey
Inhibition of antigen presentation in vitro and in vivo by MHC antagonist peptides.
International reviews of immunology 1990;6(1):49-59.
1989: Alessandro Sette; L Adorini; E Appella; S M Colón; C Miles; S Tanaka; C Ehrhardt; G Doria; Z A Nagy; Soren Buus
Structural requirements for the interaction between peptide antigens and I-Ed molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(10):3289-94.
1989: Alessandro Sette; A Lamont; Soren Buus; S M Colon; C Miles; Howard Grey
Effect of conformational propensity of peptide antigens in their interaction with MHC class II molecules. Failure to document the importance of regular secondary structures.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1268-73.
1989: Alessandro Sette; L Adorini; S M Colon; Soren Buus; Howard Grey
Capacity of intact proteins to bind to MHC class II molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1265-7.
1989: Howard Grey; Soren Buus; S Colon; C Miles; Alessandro Sette
Structural requirements and biological significance of interactions between peptides and the major histocompatibility complex.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1989;323(1217):545-52.
1989: E B Schaeffer; Alessandro Sette; D L Johnson; M C Bekoff; J A Smith; Howard Grey; Soren Buus
Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4649-53.
1989: Alessandro Sette; Soren Buus; E Appella; J A Smith; R Chesnut; C Miles; S M Colon; Howard Grey
Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3296-300.
1989: Howard Grey; S Demotz; Soren Buus; Alessandro Sette
Studies on the nature of physiologically processed antigen and on the conformation of peptides required for interaction with MHC.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():393-9.
1989: Alessandro Sette; Soren Buus; S Colon; C Miles; Howard Grey
Structural analysis of peptides capable of binding to more than one Ia antigen.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(1):35-40.
1988: Alessandro Sette; Soren Buus; S Colon; C Miles; Howard Grey
I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(1):45-8.