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Vincent Seutin

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Sebastien Dilly; Cédric Lamy; Fabian Philippart; Sylvie Poncin; Vincent Seutin; Dirk Snyders; Jean-François Liégeois
The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels.
Kumar Venkatesan; Philippe Alix; Melissa Doupagne; Alice Marquet; Isabelle Niespodziany; Bernard Rogister; Vincent Seutin
Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.
Stanislav Koulchitsky; Etienne Quertemont; Corinne Charlier; Benjamin De Backer; Vincent Seutin
Differential effects of cocaine on dopamine neuron firing in awake and anesthetized rats.

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2013: Sebastien Dilly; Cédric Lamy; Fabian Philippart; Sylvie Poncin; Vincent Seutin; Dirk Snyders; Jean-François Liégeois
The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels.
Biochemical pharmacology 2013;85(4):560-9.
2012: Kumar Venkatesan; Philippe Alix; Melissa Doupagne; Alice Marquet; Isabelle Niespodziany; Bernard Rogister; Vincent Seutin
Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.
Journal of neuroscience research 2012;90(12):2317-27.
2012: Stanislav Koulchitsky; Etienne Quertemont; Corinne Charlier; Benjamin De Backer; Vincent Seutin
Differential effects of cocaine on dopamine neuron firing in awake and anesthetized rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(7):1559-71.
2012: Sebastien Dilly; Cédric Lamy; Jean-François Liégeois; Sylvie Poncin; Vincent Seutin
[Physiology, pharmacology and modelling of potassium channels: focus on SK channels].
Médecine sciences : M/S 2012;28(4):395-402.
2012: Guillaume Drion; Alessio Franci; Vincent Seutin; Rodolphe Sepulchre
A novel phase portrait for neuronal excitability.
PloS one 2012;7(8):e41806.
2011: Eduard Badarau; Sebastien Dilly; Fabien Dufour; Sylvie Poncin; Vincent Seutin; Jean-François Liégeois
Synthesis and radioligand binding studies of bis-(8-isopropyl-isoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels.
Bioorganic & medicinal chemistry letters 2011;21(22):6756-9.
2011: Kate L Weatherall; Vincent Seutin; Jean-François Liégeois; Neil V Marrion
Crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of small-conductance calcium-activated potassium (SK) channels.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(45):18494-9.
2011: Sebastien Dilly; Cédric Lamy; Jean-François Liégeois; Neil V Marrion; Vincent Seutin
Ion-channel modulators: more diversity than previously thought.
Chembiochem : a European journal of chemical biology 2011;12(12):1808-12.
2011: Rafal M Kaminski; Zhanyan Fu; Kumar Venkatesan; Manuela Mazzuferi; Karine Leclercq; Vincent Seutin; Stefano Vicini
11-Deoxycortisol impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.
Neuropharmacology 2011;60(7-8):1098-108.
2011: Guillaume Drion; Laurent Massotte; Rodolphe Sepulchre; Vincent Seutin
How modeling can reconcile apparently discrepant experimental results: the case of pacemaking in dopaminergic neurons.
PLoS computational biology 2011;7(5):e1002050.
2010: Cédric Lamy; Jacqueline Scuvée-Moreau; Sébastien Dilly; Jean-François Liégeois; Vincent Seutin
The sigma agonist 1,3-di-o-tolyl-guanidine directly blocks SK channels in dopaminergic neurons and in cell lines.
European journal of pharmacology 2010;641(1):23-8.
2010: Cédric Lamy; Samuel J Goodchild; Kate L Weatherall; David E Jane; Jean-François Liégeois; Vincent Seutin; Neil V Marrion
Allosteric block of KCa2 channels by apamin.
The Journal of biological chemistry 2010;285(35):27067-77.
2010: Vincent Seutin; Dominique Engel
Differences in Na+ conductance density and Na+ channel functional properties between dopamine and GABA neurons of the rat substantia nigra.
Journal of neurophysiology 2010;103(6):3099-114.
2010: Guillaume Drion; Maxime Bonjean; Olivier Waroux; Jacqueline Scuvée-Moreau; Jean-François Liégeois; Terrence J Sejnowski; Rodolphe Sepulchre; Vincent Seutin
M-type channels selectively control bursting in rat dopaminergic neurons.
The European journal of neuroscience 2010;31(5):827-35.
2009: Samuel J Goodchild; Cedric Lamy; Vincent Seutin; Neil V Marrion
Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues.
The Journal of general physiology 2009;134(4):295-308.
2008: Nathalie Rouchet; Olivier Waroux; Cédric Lamy; Laurent Massotte; Jacqueline Scuvée-Moreau; Jean-François Liégeois; Vincent Seutin
SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons.
The European journal of neuroscience 2008;28(6):1108-15.
2008: Amaury Graulich; Cédric Lamy; Livia Alleva; Sébastien Dilly; Philippe CHAVATTE; Johan Wouters; Vincent Seutin; Jean-François Liégeois
Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers.
Bioorganic & medicinal chemistry letters 2008;18(11):3440-5.
2008: André J Scheen; Vincent Seutin; Luc F Van Gaal
[Endocannabinoid system in the brain...and elsewhere].
Revue médicale de Liège 2008;63(5-6):364-71.
2008: R Phan-Ba; Jacqueline Scuvée-Moreau; Vincent Seutin
[Pharmacological strategies in the modulation of central nervous system activity].
Revue médicale de Liège 2008;63(5-6):238-44.
2008: Henrik H Hansen; Olivier Waroux; Vincent Seutin; Thomas J Jentsch; Susana Aznar; Jens D Mikkelsen
Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS.
The Journal of physiology 2008;586(7):1823-32.
2007: C Defraiteur; Alain Plenevaux; Jacqueline Scuvée-Moreau; N Rouchet; D Goblet; André Luxen; Vincent Seutin
Characterization of 4-(2-hydroxyphenyl)-1-[2'-[N-(2''-pyridinyl)-p-fluorobenzamido]ethyl]piperazine (p-DMPPF) as a new potent 5-HT1A antagonist.
British journal of pharmacology 2007;152(6):952-8.
2007: Amaury Graulich; Sebastien Dilly; Amaury Farce; Jacqueline Scuvée-Moreau; Olivier Waroux; Cédric Lamy; Philippe CHAVATTE; Vincent Seutin; Jean-François Liégeois
Synthesis and radioligand binding studies of bis-isoquinolinium derivatives as small conductance Ca(2+)-activated K(+) channel blockers.
Journal of medicinal chemistry 2007;50(21):5070-5.
2007: Vincent Seutin; Jean-François Liégeois
SK channels are on the move.
British journal of pharmacology 2007;151(5):568-70.
2007: Charles Karangwa; Virginie Esters; Monique Tits; Arlette Minet; André Boland; Vincent Seutin; Alfred Noirfalise; Luc Angenot; Thierry Grisar; Agnès Foidart
Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: effects of a new natural convulsive agent.
Toxicon : official journal of the International Society on Toxinology 2007;49(8):1109-19.
2007: Laurence Ris; Brigitte Capron; Coralie Sclavons; Jean-François Liégeois; Vincent Seutin; Emile Godaux
Metaplastic effect of apamin on LTP and paired-pulse facilitation.
Learning & memory (Cold Spring Harbor, N.Y.) 2007;14(6):390-9.
2006: Amaury Graulich; Jacqueline Scuvée-Moreau; Livia Alleva; Cédric Lamy; Olivier Waroux; Vincent Seutin; Jean-François Liégeois
Synthesis and radioligand binding studies of methoxylated 1,2,3,4-tetrahydroisoquinolinium derivatives as ligands of the apamin-sensitive Ca2+-activated K+ channels.
Journal of medicinal chemistry 2006;49(24):7208-14.
2006: Henrik H Hansen; Christina Ebbesen; Claus Mathiesen; Pia Weikop; Lars Christian B Rønn; Olivier Waroux; Jacqueline Scuvée-Moreau; Vincent Seutin; Jens D Mikkelsen
The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1006-19.
2005: Sebastien Dilly; Amaury Graulich; Amaury Farce; Vincent Seutin; Jean-Francois Liegeois; Philippe CHAVATTE
Identification of a pharmacophore of SKCa channel blockers.
Journal of enzyme inhibition and medicinal chemistry 2005;20(6):517-23.
2005: Olivier Waroux; Laurent Massotte; Livia Alleva; Amaury Graulich; Elizabeth Thomas; Jean-François Liégeois; Jacqueline Scuvée-Moreau; Vincent Seutin
SK channels control the firing pattern of midbrain dopaminergic neurons in vivo.
The European journal of neuroscience 2005;22(12):3111-21.
2005: Vincent Seutin
Dopaminergic neurones: much more than dopamine?
British journal of pharmacology 2005;146(2):167-9.
2005: Amaury Graulich; Jacqueline Scuvée-Moreau; Vincent Seutin; Jean-François Liégeois
Synthesis and radioligand binding studies of C-5- and C-8-substituted 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK channel blockers related to N-methyl-laudanosine and N-methyl-noscapine.
Journal of medicinal chemistry 2005;48(15):4972-82.
2005: Antoine Adamantidis; Elizabeth Thomas; Agnès Foidart; Amélie Tyhon; Bernard Coumans; Arlette Minet; Ezio Tirelli; Vincent Seutin; Thierry Grisar; Bernard Lakaye
Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function.
The European journal of neuroscience 2005;21(10):2837-44.
2005: Amaury Graulich; F Mercier; Jacqueline Scuvée-Moreau; Vincent Seutin; Jean-François Liégeois
Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers.
Bioorganic & medicinal chemistry 2005;13(4):1201-9.
2005: P Malchair; L Van Overmeire; André Boland; Eric Salmon; Luc A Pierard; Vincent Seutin
[Coenzyme Q10: biochemistry, pathophysiology of its deficiency and potential benefit of an increased intake].
Revue médicale de Liège 2005;60(1):45-51.
2004: Charlotte Cornil; Vincent Seutin; Patrick Motte; Jacques Balthazart
Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica).
Brain research 2004;1029(2):224-40.
2004: Jacqueline Scuvée-Moreau; André Boland; Amaury Graulich; Lionel Van Overmeire; Dieter D'hoedt; Fabienne Graulich-Lorge; Elizabeth Thomas; Aude Abras; Martin Stocker; Jean-François Liégeois; Vincent Seutin
Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices.
British journal of pharmacology 2004;143(6):753-64.
2003: André Boland; Jean Gérardy; Danielle Mossay; Vincent Seutin
Pre- and post-treatment with pirlindole and dehydropirlindole protects cultured brain cells against nitric oxide-induced death.
European journal of pharmacology 2003;466(1-2):21-30.
2003: Jean-François Liégeois; F Mercier; Amaury Graulich; F Graulich-Lorge; Jacqueline Scuvée-Moreau; Vincent Seutin
Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry.
Current medicinal chemistry 2003;10(8):625-47.
2003: Vincent Seutin
[Effects of nicotine and cannabinoids on the central nervous system].
Revue médicale de Liège 2003;58(1):19-21.
2002: Charlotte Cornil; Jacques Balthazart; Patrick Motte; Laurent Massotte; Vincent Seutin
Dopamine activates noradrenergic receptors in the preoptic area.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(21):9320-30.
2002: Jacqueline Scuvee-Moreau; Jean-François Liegeois; Laurent Massotte; Vincent Seutin
Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels.
The Journal of pharmacology and experimental therapeutics 2002;302(3):1176-83.
2002: André Boland; D Delapierre; Danielle Mossay; Albert Dresse; Vincent Seutin
Effect of intermittent and continuous exposure to electromagnetic fields on cultured hippocampal cells.
Bioelectromagnetics 2002;23(2):97-105.
2002: André Boland; J Gérardy; Danielle Mossay; D Delapierre; Vincent Seutin
Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition.
British journal of pharmacology 2002;135(3):713-20.
2001: Jacqueline Scuvée-Moreau; Vincent Seutin
[Recent progress in the pharmacology of hypnotics and anxiolytics].
Revue médicale de Liège 2001;56(3):159-64.
2001: Vincent Seutin; Laurent Massotte; M F Renette; Albert Dresse
Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons.
Neuroreport 2001;12(2):255-8.
2000: Joseph Géczy; Jacques Bruhwyler; Jacqueline Scuvée-Moreau; Vincent Seutin; H Masset; J C Van Heugen; Albert Dresse; C Lejeune; Emmanuel Decamp; Lajos Szente; József Szejtli; Jean-François Liégeois
The inclusion of fluoxetine into gamma-cyclodextrin increases its bioavailability: behavioral, electrophysiological and pharmacokinetic studies.
Psychopharmacology 2000;151(4):328-34.
2000: Vincent Seutin; F Mkahli; Laurent Massotte; Albert Dresse
Calcium release from internal stores is required for the generation of spontaneous hyperpolarizations in dopaminergic neurons of neonatal rats.
Journal of neurophysiology 2000;83(1):192-7.
1999: Jean-François Liégeois; Vincent Seutin; Jacqueline Scuvée-Moreau; Albert Dresse; Jacques Bruhwyler; Joseph Géczy; Jacques Delarge; Jacques Damas
Effects of JL 3, a putative antidepressant, on rat noradrenergic and serotonergic systems.
European journal of pharmacology 1999;386(2-3):211-6.
1999: Vincent Seutin; Steven W Johnson
Recent advances in the pharmacology of quaternary salts of bicuculline.
Trends in pharmacological sciences 1999;20(7):268-70.
1998: Vincent Seutin; Laurent Massotte; Jacqueline Scuvée-Moreau; Albert Dresse
Spontaneous apamin-sensitive hyperpolarizations in dopaminergic neurons of neonatal rats.
Journal of neurophysiology 1998;80(6):3361-4.
1998: Jacqueline Scuvée-Moreau; Vincent Seutin; Albert Dresse
A quantitative pharmacological study of the cholinergic depolarization of hippocampal pyramidal cells in rat brain slices.
Archives of physiology and biochemistry 1998;105(4):365-72.
1997: Vincent Seutin; Jacqueline Scuvée-Moreau; Albert Dresse
Evidence for a non-GABAergic action of quaternary salts of bicuculline on dopaminergic neurones.
Neuropharmacology 1997;36(11-12):1653-7.
1997: Jacqueline Scuvée-Moreau; Vincent Seutin; Bernard Vrijens; Bernard Pirotte; Pascal de Tullio; Laurent Massotte; A Albert; Jacques Delarge; Albert Dresse
Effect of potassium channel openers on the firing rate of hippocampal pyramidal cells and A10 dopaminergic neurons in vitro.
Archives of physiology and biochemistry 1997;105(5):421-8.
1997: Steven W Johnson; Vincent Seutin
Bicuculline methiodide potentiates NMDA-dependent burst firing in rat dopamine neurons by blocking apamin-sensitive Ca2+-activated K+ currents.
Neuroscience letters 1997;231(1):13-6.
1996: Vincent Seutin; Ke-Zhong Shen; R A North; Steven W Johnson
Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons.
Neuroscience 1996;71(3):709-19.
1995: Vincent Seutin; Jacqueline Scuvée-Moreau; Laurent Massotte; Albert Dresse
Hydrogen peroxide hyperpolarizes rat CA1 pyramidal neurons by inducing an increase in potassium conductance.
Brain research 1995;683(2):275-8.
1994: Vincent Seutin; Steven W Johnson; R A North
Effect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons.
Neuroscience 1994;58(1):201-6.
1994: Albert Dresse; D Marechal; J Scuvee-Moreau; Vincent Seutin
Towards a pharmacological approach of Alzheimer's disease based on the molecular biology of the amyloid precursor protein (APP).
Life sciences 1994;55(25-26):2179-87.
1993: Vincent Seutin; Steven W Johnson; R A North
Apamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons.
Brain research 1993;630(1-2):341-4.
1992: Steven W Johnson; Vincent Seutin; R A North
Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump.
Science (New York, N.Y.) 1992;258(5082):665-7.
1992: Paul Verbanck; Vincent Seutin; Laurent Massotte; Albert Dresse
Differential effects of picrotoxin and RO 15-1788 on high and low ethanol concentrations on rat locus coeruleus in vitro.
European journal of pharmacology 1992;211(1):15-21.
1991: Paul Verbanck; Vincent Seutin; Laurent Massotte; Albert Dresse
Yohimbine can induce ethanol tolerance in an in vitro preparation of rat locus coeruleus.
Alcoholism, clinical and experimental research 1991;15(6):1036-9.
1991: Vincent Seutin; Paul Verbanck; Laurent Massotte; Albert Dresse
Acute amphetamine-induced subsensitivity of A10 dopamine autoreceptors in vitro.
Brain research 1991;558(1):141-4.
1990: Vincent Seutin; Jacqueline Scuvée-Moreau; I Giesbers; Laurent Massotte; Albert Dresse
Effect of BHT 920 on monoaminergic neurons of the rat brain: an electrophysiological in vivo and in vitro study.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(5):502-7.
1990: Paul Verbanck; Vincent Seutin; Albert Dresse; J Scuvée; Laurent Massotte; I Giesbers; Charles Kornreich
Electrophysiological effects of ethanol on monoaminergic neurons: an in vivo and in vitro study.
Alcoholism, clinical and experimental research 1990;14(5):728-35.
1990: Vincent Seutin; Paul Verbanck; Laurent Massotte; Albert Dresse
Evidence for the presence of N-methyl-D-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study.
Brain research 1990;514(1):147-50.
1990: Vincent Seutin; Nathalie Franchimont; Laurent Massotte; Albert Dresse
Comparison of the effect of morphine on locus coeruleus noradrenergic and ventral tegmental area dopaminergic neurons in vitro.
Life sciences 1990;46(25):1879-85.
1990: Vincent Seutin; Albert Dresse
[Electrophysiological aspects of the properties of potentially addictive drugs].
Acta psychiatrica Belgica 1990;90(1):37-45.
1989: Vincent Seutin; Laurent Massotte; Albert Dresse
Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro.
Neuropharmacology 1989;28(9):949-54.
1989: Vincent Seutin; Paul Verbanck; Laurent Massotte; Albert Dresse
Galanin decreases the activity of locus coeruleus neurons in vitro.
European journal of pharmacology 1989;164(2):373-6.
1988: Albert Dresse; Jacqueline Scuvée-Moreau; Vincent Seutin
Action of rilmenidine on locus ceruleus and dorsal raphe cells in vivo and in vitro.
The American journal of cardiology 1988;61(7):32D-34D.