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Cinzia Sevignani

Research Profile

Living Beings

Chemicals & Drugs

Procedures

Gene Expression Profiling

Genes & Molecular Sequences

Genes, Tumor Suppressor

Disorders

Physiology

Anatomy

Tumor Cells, Cultured

Co-author Network

Publications

TOP 3
Simona Rossi; Cinzia Sevignani; Stephanie C Nnadi; Linda D Siracusa; George A Calin
Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications.
Raffaele Baffa; Matteo Fassan; Cinzia Sevignani; Aldo Vecchione; Hideshi Ishii; Enrico Giarnieri; Renato V Iozzo; Leonard G Gomella; Carlo M Croce
Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Fedra Gottardo; Chang-gong liu; Manuela Ferracin; George A Calin; Matteo Fassan; Pierfrancesco Bassi; Cinzia Sevignani; Dolores Byrne; Massimo Negrini; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Micro-RNA profiling in kidney and bladder cancers.

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All Publications

2008: Simona Rossi; Cinzia Sevignani; Stephanie C Nnadi; Linda D Siracusa; George A Calin
Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(7-8):526-40.
2008: Raffaele Baffa; Matteo Fassan; Cinzia Sevignani; Aldo Vecchione; Hideshi Ishii; Enrico Giarnieri; Renato V Iozzo; Leonard G Gomella; Carlo M Croce
Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Carcinogenesis 2008;29(4):846-8.
2007: Fedra Gottardo; Chang-gong liu; Manuela Ferracin; George A Calin; Matteo Fassan; Pierfrancesco Bassi; Cinzia Sevignani; Dolores Byrne; Massimo Negrini; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Micro-RNA profiling in kidney and bladder cancers.
Urologic oncology 2007;25(5):387-92.
2007: George A Calin; Chang-gong liu; Manuela Ferracin; Terry Hyslop; Riccardo Spizzo; Cinzia Sevignani; Muller Fabbri; Amelia Cimmino; Eun Joo Lee; Sylwia E Wojcik; Masayoshi Shimizu; Esmerina Tili; Simona Rossi; Cristian Taccioli; Flavia Pichiorri; Xiuping Liu; Simona Zupo; Vlad Herlea; Laura Gramantieri; Roberta Gafà; Hansjuerg Alder; Laura Rassenti; Stefano Volinia; Thomas D Schmittgen; Thomas Kipps; Massimo Negrini; Carlo M Croce
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
Cancer cell 2007;12(3):215-29.
2007: Sai Yendamuri; Francesco Trapasso; Manuela Ferracin; Rossano Cesari; Cinzia Sevignani; Masayoshi Shimizu; Shashi Rattan; Tamotsu Kuroki; Kristoffel R Dumon; Florencia Bullrich; Chang-gong liu; Massimo Negrini; Noel N Williams; Larry R Kaiser; Carlo M Croce; George A Calin
Tumor suppressor functions of ARLTS1 in lung cancers.
Cancer research 2007;67(16):7738-45.
2007: Cinzia Sevignani; George A Calin; Stephanie C Nnadi; Masayoshi Shimizu; Ramana V Davuluri; Terry Hyslop; Peter Demant; Carlo M Croce; Linda D Siracusa
MicroRNA genes are frequently located near mouse cancer susceptibility loci.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8017-22.
2007: Pawel Wlodarski; Cinzia Sevignani; MJ Fernandes; B Calabretta; Krzysztof Wlodarski
Tumor induced by Moloney sarcoma virus causes periosteal osteogenesis engaging osteopontin, fibronectin, stromelysin-1 and tenascin.
Neoplasma 2007;54(2):173-9.
2006: Michael Dews; Asal Homayouni; Duonan Yu; Danielle A. Murphy; Cinzia Sevignani; Erik A Wentzel; Emma E Furth; William M Lee; Greg H Enders; Joshua T Mendell; Andrei Thomas-Tikhonenko
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster.
Nature genetics 2006;38(9):1060-5.
2006: Cinzia Sevignani; George A Calin; Linda D Siracusa; Carlo M Croce
Mammalian microRNAs: a small world for fine-tuning gene expression.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(3):189-202.
2006: nicola zanesi; Rami I Aqeilan; Alessandra Drusco; Mohamed Kaou; Cinzia Sevignani; Stefan Costinean; Laura Bortesi; Gaspare La Rocca; Pavel Koldovsky; Stefano Volinia; Rita Mancini; George A Calin; Charles Scott; yuri pekarsky; Carlo M Croce
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Cancer research 2006;66(2):915-20.
2005: George A Calin; Manuela Ferracin; Amelia Cimmino; Gianpiero Di Leva; Masayoshi Shimizu; Sylwia E Wojcik; Marilena V Iorio; Rosa Visone; Nurettin Ilfer Sever; Muller Fabbri; Rodolfo Iuliano; Tiziana Palumbo; Flavia Pichiorri; Claudia Roldo; Ramiro Garzon; Cinzia Sevignani; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-gong liu; Thomas Kipps; Massimo Negrini; Carlo M Croce
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia.
The New England journal of medicine 2005;353(17):1793-801.
2005: nicola zanesi; Rita Mancini; Cinzia Sevignani; Aldo Vecchione; Mohamed Kaou; Mauro Valtieri; George A Calin; yuri pekarsky; James R Gnarra; Carlo M Croce; Kay Huebner
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
Cancer research 2005;65(15):6576-82.
2005: Manuela Sarti; Cinzia Sevignani; George A Calin; Rami I Aqeilan; Masayoshi Shimizu; Francesca Pentimalli; Maria Cristina Picchio; Andrew Godwin; Anne Rosenberg; Alessandra Drusco; Massimo Negrini; Carlo M Croce
Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):806-13.
2004: Aldo Vecchione; Cinzia Sevignani; Enrico Giarnieri; nicola zanesi; Hideshi Ishii; Rossano Cesari; Louise Y Y Fong; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
Inactivation of the FHIT gene favors bladder cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7607-12.
2004: George A Calin; Chang-gong liu; Cinzia Sevignani; Manuela Ferracin; Nadia Felli; Calin Dan Dumitru; Masayoshi Shimizu; Amelia Cimmino; Simona Zupo; Mariella Dono; Marie L Dell'Aquila; Hansjuerg Alder; Laura Rassenti; Thomas Kipps; Florencia Bullrich; Massimo Negrini; Carlo M Croce
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11755-60.
2004: Chang-gong liu; George A Calin; Brian Meloon; Nir Gamliel; Cinzia Sevignani; Manuela Ferracin; Calin Dan Dumitru; Masayoshi Shimizu; Simona Zupo; Mariella Dono; Hansjuerg Alder; Florencia Bullrich; Massimo Negrini; Carlo M Croce
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9740-4.
2004: Andrei Thomas-Tikhonenko; Isabelle Viard-Leveugle; Michael Dews; Philippe Wehrli; Cinzia Sevignani; Duonan Yu; Stacey Ricci; Wafik S El-Deiry; Bruce Aronow; Gürkan Kaya; Jean-Hilaire Saurat; Lars E French
Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo.
Cancer research 2004;64(9):3126-36.
2004: George A Calin; Cinzia Sevignani; Calin Dan Dumitru; Terry Hyslop; Evan Noch; Sai Yendamuri; Masayoshi Shimizu; Shashi Rattan; Florencia Bullrich; Massimo Negrini; Carlo M Croce
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2999-3004.
2003: Cinzia Sevignani; George A Calin; Rossano Cesari; Manuela Sarti; Hideshi Ishii; Sai Yendamuri; Aldo Vecchione; Francesco Trapasso; Carlo M Croce
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
Cancer research 2003;63(6):1183-7.
2002: Bruce C Turner; Michelle Ottey; Drazen Zimonjic; Magdalena B Potoczek; Walter W Hauck; Ed Pequignot; Catherine L Keck-Waggoner; Cinzia Sevignani; C Marcelo Aldaz; Peter McCue; Juan P Palazzo; Kay Huebner; Nicholas C Popescu
The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.
Cancer research 2002;62(14):4054-60.
2001: Christopher A Hunter; Duonan Yu; Michael S Gee; CV Ngo; Cinzia Sevignani; Michael H Goldschmidt; Tatyana V Golovkina; S Evans; W F Lee; Andrei Thomas-Tikhonenko
Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):5878-81.
2000: M Cervellera; G Raschella; Giorgia Santilli; Barbara Tanno; Andrea Ventura; Camillo Mancini; Cinzia Sevignani; Bruno Calabretta; A Sala
Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB.
The Journal of biological chemistry 2000;275(28):21055-60.
2000: A Janz; Cinzia Sevignani; K Kenyon; CV Ngo; Andrei Thomas-Tikhonenko
Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA.
Nucleic acids research 2000;28(11):2268-75.
1999: Cinzia Sevignani; A Cranston; Renato V Iozzo; Richard Fishel; Bruno Calabretta
Spontaneous and mutagen-induced transformation of primary cultures of Msh2-/- p53-/- colonocytes.
Cancer research 1999;59(23):5882-6.
1998: Cinzia Sevignani; Pawel Wlodarski; J Kirillova; W E Mercer; K G Danielson; Renato V Iozzo; Bruno Calabretta
Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene.
The Journal of clinical investigation 1998;101(8):1572-80.
1998: Pawel Wlodarski; Mariusz A Wasik; Mariusz Z Ratajczak; Cinzia Sevignani; Grazyna Hoser; Jerzy Kawiak; Alan M Gewirtz; Bruno Calabretta; Tomasz Skorski
Role of p53 in hematopoietic recovery after cytotoxic treatment.
Blood 1998;91(8):2998-3006.