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Harriet Seward

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Harriet E Seward; Jaswir Kaur; Roanne Denton; Frederick W Muskett; Mark Pfuhl; Clive R Bagshaw
Halide and proton binding kinetics of yellow fluorescent protein variants.
Harriet E Seward; Clive R Bagshaw
The photochemistry of fluorescent proteins: implications for their biological applications.
Hazel M Girvan; Helen S Toogood; Rachael E Littleford; Harriet E Seward; W Ewen Smith; Idorenyin S Ekanem; David Leys; Myles R Cheesman; Andrew W Munro
Novel haem co-ordination variants of flavocytochrome P450BM3.

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All Publications

2013: Harriet E Seward; Jaswir Kaur; Roanne Denton; Frederick W Muskett; Mark Pfuhl; Clive R Bagshaw
Halide and proton binding kinetics of yellow fluorescent protein variants.
Biochemistry 2013;52(14):2482-91.
2009: Harriet E Seward; Clive R Bagshaw
The photochemistry of fluorescent proteins: implications for their biological applications.
Chemical Society reviews 2009;38(10):2842-51.
2009: Hazel M Girvan; Helen S Toogood; Rachael E Littleford; Harriet E Seward; W Ewen Smith; Idorenyin S Ekanem; David Leys; Myles R Cheesman; Andrew W Munro
Novel haem co-ordination variants of flavocytochrome P450BM3.
The Biochemical journal 2009;417(1):65-76.
2008: Kirsty J McLean; Paul Carroll; D Geraint Lewis; Adrian J Dunford; Harriet E Seward; Rajasekhar Neeli; Myles R Cheesman; Laurent Marsollier; Philip Douglas; W Ewen Smith; Ida Rosenkrands; Stewart T Cole; David Leys; Tanya Parish; Andrew W Munro
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
The Journal of biological chemistry 2008;283(48):33406-16.
2008: Nishma Chauhan; Jaswir Basran; Igor Efimov; Dimitri A Svistunenko; Harriet E Seward; Peter C E Moody; Emma Lloyd Raven
The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenase.
Biochemistry 2008;47(16):4761-9.
2007: Xinghua Shi; Jaswir Basran; Harriet E Seward; William Childs; Clive R Bagshaw; Steven G Boxer
Anomalous negative fluorescence anisotropy in yellow fluorescent protein (YFP 10C): quantitative analysis of FRET in YFP dimers.
Biochemistry 2007;46(50):14403-17.
2007: Adrian J Dunford; Kirsty J McLean; Muna Sabri; Harriet E Seward; Derren J Heyes; Nigel S Scrutton; Andrew W Munro
Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1. Analysis of CO complexation reactions and reversibility of the P450/P420 equilibrium.
The Journal of biological chemistry 2007;282(34):24816-24.
2007: Hazel M Girvan; Harriet E Seward; Helen S Toogood; Myles R Cheesman; David Leys; Andrew W Munro
Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
The Journal of biological chemistry 2007;282(1):564-72.
2006: Harriet E Seward; Anna Roujeinikova; Kirsty J McLean; Andrew W Munro; David Leys
Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.
The Journal of biological chemistry 2006;281(51):39437-43.
2006: Kirsty J McLean; Adrian J Dunford; Muna Sabri; Rajasekhar Neeli; Hazel M Girvan; Philip R Balding; David Leys; Harriet E Seward; Ker R Marshall; Andrew W Munro
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.
Biochemical Society transactions 2006;34(Pt 6):1178-82.
2006: Wei Zeng; Harriet E Seward; András Málnási-Csizmadia; Stuart Wakelin; Robert J Woolley; Gurpreet S Cheema; Jaswir Basran; Trushar R Patel; Arthur J Rowe; Clive R Bagshaw
Resonance energy transfer between green fluorescent protein variants: complexities revealed with myosin fusion proteins.
Biochemistry 2006;45(35):10482-91.
2006: Sandip K Badyal; M Gordon Joyce; Katherine H Sharp; Harriet E Seward; Martin Mewies; Jaswir Basran; Isabel K Macdonald; Peter C E Moody; Emma Lloyd Raven
Conformational mobility in the active site of a heme peroxidase.
The Journal of biological chemistry 2006;281(34):24512-20.
2006: Kirsty J McLean; Ashley J Warman; Harriet E Seward; Ker R Marshall; Hazel M Girvan; Myles R Cheesman; Michael R Waterman; Andrew W Munro
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.
Biochemistry 2006;45(27):8427-43.
2005: Harriet E Seward; Hazel M Girvan; Andrew W Munro
Cytochrome P450s: creating novel ligand sets.
Dalton transactions (Cambridge, England : 2003) 2005;(21):3419-26.
2005: Nektaria D Papadopoulou; Martin Mewies; Kirsty J McLean; Harriet E Seward; Dimitri A Svistunenko; Andrew W Munro; Emma Lloyd Raven
Redox and spectroscopic properties of human indoleamine 2,3-dioxygenase and a His303Ala variant: implications for catalysis.
Biochemistry 2005;44(43):14318-28.
2005: Ashley J Warman; Olivier Roitel; Rajasekhar Neeli; Hazel M Girvan; Harriet E Seward; S A Murray; Kirsty J McLean; M Gordon Joyce; Helen S Toogood; R A Holt; David Leys; Nigel S Scrutton; Andrew W Munro
Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme.
Biochemical Society transactions 2005;33(Pt 4):747-53.
2004: Luca Quaroni; Harriet E Seward; Kirsty J McLean; Hazel M Girvan; Tobias W B Ost; Michael A Noble; Sharon M Kelly; Nicholas C Price; Myles R Cheesman; W Ewen Smith; Andrew W Munro
Interaction of nitric oxide with cytochrome P450 BM3.
Biochemistry 2004;43(51):16416-31.
2004: Thomas A Clarke; Victoria Dennison; Harriet E Seward; Bénédicte Burlat; Jeffrey A Cole; Andrew M Hemmings; David J Richardson
Purification and spectropotentiometric characterization of Escherichia coli NrfB, a decaheme homodimer that transfers electrons to the decaheme periplasmic nitrite reductase complex.
The Journal of biological chemistry 2004;279(40):41333-9.
2003: Neesha Patel; Harriet E Seward; Agneta Svensson; Stephen J Gurman; Andrew J Thomson; Emma Lloyd Raven
Exploiting the conformational flexibility of leghemoglobin: a framework for examination of heme protein axial ligation.
Archives of biochemistry and biophysics 2003;418(2):197-204.
2003: Katy E Pitts; Paul S Dobbin; Francisca Reyes-Ramirez; Andrew J Thomson; David J Richardson; Harriet E Seward
Characterization of the Shewanella oneidensis MR-1 decaheme cytochrome MtrA: expression in Escherichia coli confers the ability to reduce soluble Fe(III) chelates.
The Journal of biological chemistry 2003;278(30):27758-65.
2002: Vicki A Bamford; Hayley C Angove; Harriet E Seward; Andrew J Thomson; Jeffrey A Cole; Julea N Butt; Andrew M Hemmings; David J Richardson
Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli.
Biochemistry 2002;41(9):2921-31.
1997: Clive S Butler; Harriet E Seward; C Greenwood; Andrew J Thomson
Fast cytochrome bo from Escherichia coli binds two molecules of nitric oxide at CuB.
Biochemistry 1997;36(51):16259-66.