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Hitomi Sezaki

Research Profile

Chemicals & Drugs

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Drug Therapy, Combination

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Japan

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TOP 3
Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy with miriplatin for hepatocellular carcinoma patients with chronic renal failure: report of three cases.
Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Tetsuro Kobayashi
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.

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All Publications

2013: Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
Journal of medical virology 2013;85(6):1028-36.
2013: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy with miriplatin for hepatocellular carcinoma patients with chronic renal failure: report of three cases.
Gut and liver 2013;7(2):246-51.
2013: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Tetsuro Kobayashi
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.
Hepatology (Baltimore, Md.) 2013;57(3):964-73.
2013: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Efficacy and anticarcinogenic activity of ribavirin combination therapy for hepatitis C virus-related compensated cirrhosis.
Intervirology 2013;56(1):37-45.
2013: Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C Virus core region and lipid metabolism are associated with hepatocarcinogenesis in nonresponders to interferon plus ribavirin combination therapy.
Intervirology 2013;56(1):13-21.
2012: Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2012;56(6):2134-41.
2012: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.
Journal of medical virology 2012;84(10):1593-9.
2012: Yasuji Arase; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 1b and high viral load.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(10):949-57.
2012: Atsushi Ono; Satoshi Saitou; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients.
Journal of hepatology 2012;57(3):508-14.
2012: Nami Mori; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Hiromitsu Kumada
Determinants of the clinical outcome of patients with severe acute exacerbation of chronic hepatitis B virus infection.
Journal of gastroenterology 2012;47(9):1022-9.
2012: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 2 and high virus load.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(8):750-6.
2012: Makiko Takeyasu; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Long-term interferon monotherapy reduces the risk of HCV-associated hepatocellular carcinoma.
Journal of medical virology 2012;84(8):1199-207.
2012: Fumitaka Suzuki; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Yuzo Miyakawa; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2012;54(4):352-4.
2012: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1.
Journal of medical virology 2012;84(7):1097-105.
2012: Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Hiromitsu Kumada
Long-term efficacy of interferon therapy in patients with chronic hepatitis B virus infection in Japan.
Journal of gastroenterology 2012;47(7):814-22.
2012: Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada; Kaoru Aida; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Tetsuro Kobayashi
Prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhosis with fasting plasma glucose level of <126 mg/dL.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(6):558-63.
2012: Mariko Kobayashi; Norio Akuta; Yasuji Arase; Kazuaki Chayama; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Yuzo Miyakawa; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.
Journal of gastroenterology 2012;47(5):596-605.
2012: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy using miriplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma.
Japanese journal of clinical oncology 2012;42(3):175-82.
2012: Yasuji Arase; Tetsuya Hosaka; Shiun Dong Hsieh; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Naoki Matsumoto; Kyoko Ogawa; Yuki Ohmoto; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Maho Tanabe; Hiroshi Tsuji; Norio Akuta; Kazuhisa Amakawa; Tetsuro Kobayashi
Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(3):264-72.
2012: Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Kazuhisa Amakawa; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yuki Ohmoto; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiroshi Tsuji; Hiromitsu Kumada
Large-scale long-term follow-up study of Japanese patients with non-alcoholic Fatty liver disease for the onset of hepatocellular carcinoma.
The American journal of gastroenterology 2012;107(2):253-61.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Intervirology 2012;55(3):231-41.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromi Yatsuji; Hiromitsu Kumada
Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Intervirology 2012;55(6):417-25.
2011: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Naoki Matsumoto; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
[Transcatheter arterial chemotherapy with miriplatin for patients with hepatocellular carcinoma and chronic renal failure].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(11):1872-8.
2011: Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Highly sensitive AFP-L3% assay is useful for predicting recurrence of hepatocellular carcinoma after curative treatment pre- and postoperatively.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(11):1036-45.
2011: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Naoki Matsumoto; Kyoko Ogawa; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Development rate of chronic kidney disease in hepatitis C virus patients with advanced fibrosis after interferon therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(10):946-54.
2011: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy.
Journal of medical virology 2011;83(6):1016-22.
2011: Yasuji Arase; Fumitaka Suzuki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yusuke Kawamura; Naoki Matsumoto; Norio Akuta; Norihisa Imai; Mariko Kobayashi; Hitomi Sezaki; Satoshi Saito; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada; Yuki Ohmoto; Kazuhisa Amakawa; Hiroshi Tsuji; Shiun Dong Hsieh; Tetsurou Kobayashi
Efficacy and safety in sitagliptin therapy for diabetes complicated by chronic liver disease caused by hepatitis C virus.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(6):524-9.
2011: Kenji Ikeda; Masahiro Kobayashi; Yusuke Kawamura; Norihiro Imai; Yuya Seko; Miharu Hirakawa; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Stage progression of small hepatocellular carcinoma after radical therapy: comparisons of radiofrequency ablation and surgery using the Markov model.
Liver international : official journal of the International Association for the Study of the Liver 2011;31(5):692-9.
2011: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saito; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Kazuaki Chayama; Naoyuki Kamatani; Yusuke Nakamura; Yuzo Miyakawa; Hiromitsu Kumada
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Hepatology (Baltimore, Md.) 2011;53(2):415-21.
2011: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients.
Internal medicine (Tokyo, Japan) 2011;50(19):2083-8.
2011: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Previous chemoembolization response after transcatheter arterial chemoembolization (TACE) can predict the anti-tumor effect of subsequent TACE with miriplatin in patients with recurrent hepatocellular carcinoma.
Oncology 2011;80(3-4):188-94.
2011: Yasuji Arase; Fumitaka Suzuki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yusuke Kawamura; Naoki Matsumoto; Norio Akuta; Mariko Kobayashi; Hitomi Sezaki; Satoshi Saito; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada; Yuki Ohmoto; Kazuhisa Amakawa; Hiroshi Tsuji; Shiun Dong Hsieh; Kazuhisa Kato; Maho Tanabe; Kyoko Ogawa; Shigeko Hara; Tetsuro Kobayashi
The development of chronic kidney disease in Japanese patients with non-alcoholic fatty liver disease.
Internal medicine (Tokyo, Japan) 2011;50(10):1081-7.
2010: Kenji Ikeda; Masahiro Kobayashi; Yuya Seko; Norihiro Imai; Miharu Hirakawa; Yusuke Kawamura; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: A retrospective study of hepatitis C virus-related liver cancer.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(12):1168-75.
2010: Tetsuya Hosaka; Fumitaka Suzuki; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(10):1461-70.
2010: Yusuke Kawamura; Kenji Ikeda; Miharu Hirakawa; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
New classification of dynamic computed tomography images predictive of malignant characteristics of hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(10):1006-14.
2010: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; Yusuke Nakamura; Hiromitsu Kumada
Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Hepatology (Baltimore, Md.) 2010;52(2):421-9.
2010: Yoshiyuki Suzuki; Kenji Ikeda; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Fumitaka Suzuki; Satoshi Saitoh; Yasuji Arase; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Association of HLA-DR14 with the treatment response in Japanese patients with autoimmune hepatitis.
Digestive diseases and sciences 2010;55(7):2070-6.
2010: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Efficacy of switching to entecavir monotherapy in Japanese lamivudine-pretreated patients.
Journal of gastroenterology and hepatology 2010;25(5):892-8.
2010: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region of genotype 1b affect very early viral dynamics during treatment with telaprevir, peginterferon, and ribavirin.
Journal of medical virology 2010;82(4):575-82.
2010: Yoshimasa Hashimoto; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saito; Yoshiyuki Suzuki; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Clinical and virological effects of long-term (over 5 years) lamivudine therapy.
Journal of medical virology 2010;82(4):684-91.
2010: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Hitomi Sezaki; Tetsuya Hosaka; Yusuke Kawamura; Hiromi Yatsuji; Miharu Hirakawa; Kenji Ikeda; Shiun Dong Hsieh; Yuki Oomoto; Kazuhisa Amakawa; Hisahito Kato; Tamae Kazawa; Hiroshi Tsuji; Tetsuro Kobayashi; Hiromitsu Kumada
Virus clearance reduces bone fracture in postmenopausal women with osteoporosis and chronic liver disease caused by hepatitis C virus.
Journal of medical virology 2010;82(3):390-5.
2010: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Yusuke Kawamura; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Hiromitsu Kumada
Correlation of YMDD mutation and breakthrough hepatitis with hepatitis B virus DNA and serum ALT during lamivudine treatment.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(2):125-34.
2010: Tetsuya Hosaka; Fumitaka Suzuki; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yastuji; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Development of HCC in patients receiving adefovir dipivoxil for lamivudine-resistant hepatitis B virus mutants.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(2):145-52.
2010: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Naoki Matsumoto; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 2 and high virus load.
Internal medicine (Tokyo, Japan) 2010;49(11):965-70.
2010: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 1b and high virus load.
Internal medicine (Tokyo, Japan) 2010;49(11):957-63.
2010: Norio Akuta; Fumitaka Suzuki; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Extending combination therapy with peginterferon plus ribavirin for genotype 2 chronic hepatitis C virological responders: a pilot study of 7 cases.
Intervirology 2010;53(3):188-92.
2010: Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Influence of amino-acid polymorphism in the core protein on progression of liver disease in patients infected with hepatitis C virus genotype 1b.
Journal of medical virology 2010;82(1):41-8.
2010: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Hiromi Yatsuji; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Hiromitsu Kumada
Sustained virological response in a patient with chronic hepatitis C treated by monotherapy with the NS3-4A protease inhibitor telaprevir.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2010;47(1):76-8.
2009: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(11):1056-63.
2009: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada; Tetsuro Kobayashi
Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C.
Journal of medical virology 2009;81(9):1584-90.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.
Journal of medical virology 2009;81(6):1032-9.
2009: Hitomi Sezaki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Poor response to pegylated interferon and ribavirin in older women infected with hepatitis C virus of genotype 1b in high viral loads.
Digestive diseases and sciences 2009;54(6):1317-24.
2009: Kenji Ikeda; Yasuji Arase; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Necessities of interferon therapy in elderly patients with chronic hepatitis C.
The American journal of medicine 2009;122(5):479-86.
2009: Daisuke Morihara; Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Hiromi Saneto; Hiromi Yatuji; Tetuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitu Kumada
Effectiveness of combination therapy of splenectomy and long-term interferon in patients with hepatitis C virus-related cirrhosis and thrombocytopenia.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(5):439-47.
2009: Tetsuya Hosaka; Kenji Ikeda; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
Predictive factors of advanced recurrence after curative resection of small hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(5):736-42.
2009: Yusuke Kawamura; Kenji Ikeda; Miharu Hirakawa; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Efficacy of platinum analogue for advanced hepatocellular carcinoma unresponsive to transcatheter arterial chemoembolization with epirubicin.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(4):346-54.
2009: Yoshiyuki Suzuki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Efficacy of entecavir treatment for lamivudine-resistant hepatitis B over 3 years: histological improvement or entecavir resistance?
Journal of gastroenterology and hepatology 2009;24(3):429-35.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
A matched case-controlled study of 48 and 72 weeks of peginterferon plus ribavirin combination therapy in patients infected with HCV genotype 1b in Japan: amino acid substitutions in HCV core region as predictor of sustained virological response.
Journal of medical virology 2009;81(3):452-8.
2009: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Kenji Ikeda; Hiromitsu Kumada
Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C.
Hepatology (Baltimore, Md.) 2009;49(3):739-44.
2009: Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma.
Cancer 2009;115(3):571-80.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 2a high viral load and virological response to interferon-ribavirin combination therapy.
Intervirology 2009;52(6):301-9.
2009: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
The efficacy of interferon-beta monotherapy for elderly patients with type C hepatitis of genotype 2.
Internal medicine (Tokyo, Japan) 2009;48(16):1337-42.
2009: Suguru Ogura; Norio Akuta; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological and biochemical features in elderly HCV patients with hepatocellular carcinoma: amino acid substitutions in HCV core region as predictor of mortality after first treatment.
Intervirology 2009;52(4):179-88.
2009: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Yuzo Miyakawa; Hiromitsu Kumada
Development of hepatocellular carcinoma in elderly patients with chronic hepatitis C with or without elevated aspartate and alanine aminotransferase levels.
Scandinavian journal of gastroenterology 2009;44(8):975-83.
2009: Hitomi Sezaki; Fumitaka Suzuki; Norio Akuta; Hiromi Yatsuji; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
An open pilot study exploring the efficacy of fluvastatin, pegylated interferon and ribavirin in patients with hepatitis C virus genotype 1b in high viral loads.
Intervirology 2009;52(1):43-8.
2009: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Combination therapy of peginterferon and ribavirin for chronic hepatitis C patients with genotype 1b and low-virus load.
Internal medicine (Tokyo, Japan) 2009;48(5):253-8.
2008: Mariko Kobayashi; Kenji Ikeda; Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Masahiro Kobayashi; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Change of hepatitis B virus genotypes in acute and chronic infections in Japan.
Journal of medical virology 2008;80(11):1880-4.
2008: Yusuke Kawamura; Kenji Ikeda; Yasuji Arase; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Diabetes mellitus worsens the recurrence rate after potentially curative therapy in patients with hepatocellular carcinoma associated with nonviral hepatitis.
Journal of gastroenterology and hepatology 2008;23(11):1739-46.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Hiromitsu Kumada
Hepatitis C virus enhances incidence of idiopathic pulmonary fibrosis.
World journal of gastroenterology : WJG 2008;14(38):5880-6.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Satoshi Saito; Kenji Ikeda; Hiromitsu Kumada
Potential of laparoscopy in chronic liver disease with hepatitis B and C viruses.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(9):877-85.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy of low-dose intermittent interferon-alpha monotherapy in patients infected with hepatitis C virus genotype 1b who were predicted or failed to respond to pegylated interferon plus ribavirin combination therapy.
Journal of medical virology 2008;80(8):1363-9.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma.
Journal of medical virology 2008;80(8):1354-62.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada
Prolonged-efficacy of bisphosphonate in postmenopausal women with osteoporosis and chronic liver disease.
Journal of medical virology 2008;80(7):1302-7.
2008: Hiromi Yatsuji; Fumitaka Suzuki; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Satomi Iwasaki; Mariko Kobayashi; Hiromitsu Kumada
Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up.
Journal of hepatology 2008;48(6):923-31.
2008: Miharu Hirakawa; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
New ablation procedure for a radiofrequency liver tissue coagulation system using an expandable needle.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(2):214-9.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological response and hepatocarcinogenesis in lamivudine-resistant hepatitis B virus genotype C patients treated with lamivudine plus adefovir dipivoxil.
Intervirology 2008;51(6):385-93.
2008: Miharu Hirakawa; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Lipiodol and dye at the site of ablation decreases during RFA.
Intervirology 2008;51(5):362-8.
2008: Yoshio Katamura; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Hiromi Yatsuji; Norihiro Nomura; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saito; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Natural human interferon beta plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus and a high viral load.
Internal medicine (Tokyo, Japan) 2008;47(21):1827-34.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
The efficacy of 24-week interferon monotherapy for type C liver cirrhosis in Japanese patients with genotype 1b and low virus load.
Intervirology 2008;51(4):265-9.
2008: Miharu Hirakawa; Kenji Ikeda; Yasuji Arase; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Hepatocarcinogenesis following HCV RNA eradication by interferon in chronic hepatitis patients.
Internal medicine (Tokyo, Japan) 2008;47(19):1637-43.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Suitable treatment period in patients with virological response during combination therapy of peginterferon and ribavirin for chronic hepatitis C.
Internal medicine (Tokyo, Japan) 2008;47(14):1301-7.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
The efficacy of short-term interferon-beta therapy for type C cirrhotic patients with genotype 2a and low virus load.
Internal medicine (Tokyo, Japan) 2008;47(12):1085-90.
2008: Yusuke Kawamura; Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Mariko Kobayashi; Hiromitsu Kumada
The efficacy of short-term interferon-beta therapy for chronic hepatitis C patients with low virus load.
Internal medicine (Tokyo, Japan) 2008;47(5):355-60.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Efficacy in patients with dose reduction in combination therapy of peginterferon and ribavirin for chronic hepatitis C.
Intervirology 2008;51(1):1-6.
2008: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Changes in viral loads of lamivudine-resistant mutants during entecavir therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(2):132-40.
2007: Yusuke Kawamura; Kenji Ikeda; Yasuji Arase; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Viral elimination reduces incidence of malignant lymphoma in patients with hepatitis C.
The American journal of medicine 2007;120(12):1034-41.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictors of viral kinetics to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Journal of medical virology 2007;79(11):1686-95.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2007;46(5):1357-64.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Interferon-induced prolonged biochemical response reduces hepatocarcinogenesis in hepatitis C virus infection.
Journal of medical virology 2007;79(10):1485-90.
2007: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Hiromi Yatsuji; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Loss of hepatitis B surface antigen from the serum of patients with chronic hepatitis treated with lamivudine.
Journal of medical virology 2007;79(10):1472-7.
2007: Eiko Hasegawa; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy and anticarcinogenic activity of interferon for hepatitis C virus-related compensated cirrhosis in patients with genotype 1b low viral load or genotype 2.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(10):793-800.
2007: Hitomi Sezaki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Evaluation of long-term biochemical responses to combination therapy of interferon plus ribavirin in those infected with hepatitis C virus genotype 1b and high baseline viral load.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(10):787-92.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Comparison of interferon and lamivudine treatment in Japanese patients with HBeAg positive chronic hepatitis B.
Journal of medical virology 2007;79(9):1286-92.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Masahiro Kobayashi; Hiromitsu Kumada
Prolonged-interferon therapy reduces hepatocarcinogenesis in aged-patients with chronic hepatitis C.
Journal of medical virology 2007;79(8):1095-102.
2007: Yuichi Torisu; Kenji Ikeda; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yusuke Kawamura; Hiromi Yatsuji; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Diabetes mellitus increases the risk of hepatocarcinogenesis in patients with alcoholic cirrhosis: A preliminary report.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(7):517-23.
2007: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Yusuke Kawamura; Tetsuya Hosaka; Mariko Kobayashi; Kenji Ikeda; Masahiro Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Selection of a virus strain resistant to entecavir in a nucleoside-naive patient with hepatitis B of genotype H.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;39(2):149-52.
2007: Tomokazu Kawaoka; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Yasuji Arase; Hitomi Sezaki; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Efficacy of lamivudine therapy in elderly patients with chronic hepatitis B infection.
Journal of gastroenterology 2007;42(5):395-401.
2007: Tetsuya Hosaka; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Factors associated with the virological response of lamivudine-resistant hepatitis B virus during combination therapy with adefovir dipivoxil plus lamivudine.
Journal of gastroenterology 2007;42(5):368-74.
2007: Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Randomized controlled trial for the efficacy of hepatic arterial occlusion during radiofrequency ablation for small hepatocellular carcinoma--direct ablative effects and a long-term outcome.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(3):353-9.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholesterol levels.
Journal of hepatology 2007;46(3):403-10.
2007: Norio Chihara; Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Masahiro Kobayashi; Sachiyo Watahiki; Kenji Ikeda; Hiromitsu Kumada
Prolonged hepatitis after acute infection with genotype H hepatitis B virus.
Internal medicine (Tokyo, Japan) 2007;46(22):1847-51.
2007: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Side effects of combination therapy of peginterferon and ribavirin for chronic hepatitis-C.
Internal medicine (Tokyo, Japan) 2007;46(22):1827-32.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Prediction of response to pegylated interferon and ribavirin in hepatitis C by polymorphisms in the viral core protein and very early dynamics of viremia.
Intervirology 2007;50(5):361-8.
2007: Yasuji Arase; Kenji Ikeda; Yoshiyuki Suzuki; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Serum KL-6 level is elevated in chronic hepatitis C patients with combination therapy of pegylated interferon and ribavirin.
Internal medicine (Tokyo, Japan) 2007;46(15):1155-60.
2007: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Junko Sato; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Long-term presence of HBV in the sera of chronic hepatitis B patients with HBsAg seroclearance.
Intervirology 2007;50(3):161-5.
2006: Takashi Someya; Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: a pilot study of patients with hepatitis B virus-related cirrhosis.
Journal of gastroenterology 2006;41(12):1206-13.
2006: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitsu Kumada
Long-term outcome of HBV carriers with negative HBe antigen and normal aminotransferase.
The American journal of medicine 2006;119(11):977-85.
2006: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Satomi Iwasaki; Junko Sato; Sachiyo Watahiki; Yuzo Miyakawa; Hiromitsu Kumada
Response to long-term lamivudine treatment in patients infected with hepatitis B virus genotypes A, B, and C.
Journal of medical virology 2006;78(10):1276-83.
2006: Kiminori Uka; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy of interferon monotherapy in young adult patients with chronic hepatitis C virus infection.
Journal of gastroenterology 2006;41(5):470-5.
2006: Masahiro Kobayashi; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Yuzo Miyakawa; Hiromitsu Kumada
Natural history of compensated cirrhosis in the Child-Pugh class A compared between 490 patients with hepatitis C and 167 with B virus infections.
Journal of medical virology 2006;78(4):459-65.
2006: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitsu Kumada
A long-term glycyrrhizin injection therapy reduces hepatocellular carcinogenesis rate in patients with interferon-resistant active chronic hepatitis C: a cohort study of 1249 patients.
Digestive diseases and sciences 2006;51(3):603-9.
2006: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Yasuji Arase; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Junko Satoh; Sachiyo Watahiki; Hiromitsu Kumada
Clinical and virological features of non-breakthrough and severe exacerbation due to lamivudine-resistant hepatitis B virus mutants.
Journal of medical virology 2006;78(3):341-52.
2006: Masahiro Kobayashi; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
Dysplastic nodules frequently develop into hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis.
Cancer 2006;106(3):636-47.
2006: Hitomi Sezaki; Fumitaka Suzuki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Long-term follow-up of HBeAg-positive young adult Japanese patients treated with corticosteroid withdrawal therapy for chronic hepatitis B.
Intervirology 2006;49(6):339-45.
2006: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Yoshiyuki Suzuki; Fumitaka Suzuki; Norio Akuta; Yasuji Arase; Hiromitsu Kumada
Origin of neovascular structure in an early stage of hepatocellular carcinoma: study of alpha-smooth muscle actin immunohistochemistry in serial thin sections of surgically resected cancer.
Journal of gastroenterology and hepatology 2006;21(1 Pt 1):183-90.
2006: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Long-term outcome after hepatitis B surface antigen seroclearance in patients with chronic hepatitis B.
The American journal of medicine 2006;119(1):71.e9-16.
2006: Norio Akuta; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Sachiyo Watahiki; Junko Sato; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load.
Journal of medical virology 2006;78(1):83-90.
2006: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Anticarcinogenic impact of interferon on patients with chronic hepatitis C: a large-scale long-term study in a single center.
Intervirology 2006;49(1-2):82-90.
2005: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Yoshiyuki Suzuki; Fumitaka Suzuki; Norio Akuta; Yasuji Arase; Hiromitsu Kumada; Masamichi Matsuda; Masaji Hashimoto; Goro Watanabe
Cost-effectiveness of radiofrequency ablation and surgical therapy for small hepatocellular carcinoma of 3cm or less in diameter.
Hepatology research : the official journal of the Japan Society of Hepatology 2005;33(3):241-9.
2005: Yusuke Kawamura; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Determinants of serum ALT normalization after phlebotomy in patients with chronic hepatitis C infection.
Journal of gastroenterology 2005;40(9):901-6.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Long-term follow-up of interferon monotherapy in 454 consecutive naive patients infected with hepatitis C virus: multi-course interferon therapy may reduce the risk of hepatocellular carcinoma and increase survival.
Scandinavian journal of gastroenterology 2005;40(6):688-96.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Masahiro Kobayashi; Hiromitsu Kumada
Hepatocyte steatosis is an important predictor of response to interferon (IFN) monotherapy in Japanese patients infected with HCV genotype 2a: Virological features of IFN-resistant cases with hepatocyte steatosis.
Journal of medical virology 2005;75(4):550-8.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Favorable efficacy of long-term lamivudine therapy in patients with chronic hepatitis B: an 8-year follow-up study.
Journal of medical virology 2005;75(4):491-8.
2005: Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Fumitaka Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Lamivudine monotherapy for spontaneous severe acute exacerbation of chronic hepatitis B.
Journal of gastroenterology and hepatology 2005;20(3):426-32.
2005: Nobuhiko Hiraga; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Marie Matsuda; Sachiyo Watabiki; Junko Satoh; Hiromitsu Kumada
Clinical and virological characteristics of untreated patients with chronic hepatitis C who develop serum alanine aminotransferase flare-up.
Journal of medical virology 2005;75(2):240-8.
2005: Norio Akuta; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Sachiyo Watahiki; Junko Sato; Marie Matsuda; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.
Intervirology 2005;48(6):372-80.
2005: Norio Akuta; Fumitaka Suzuki; Mariko Kobayashi; Marie Matsuda; Junko Sato; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological and biochemical relapse after discontinuation of lamivudine monotherapy for chronic hepatitis B in Japan: comparison with breakthrough hepatitis during long-term treatment.
Intervirology 2005;48(2-3):174-82.
2005: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Hiromitsu Kumada
Significance of serum ribavirin concentration in combination therapy of interferon and ribavirin for chronic hepatitis C.
Intervirology 2005;48(2-3):138-44.
2005: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Satoshi Saitoh; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Hepatitis B virus-related hepatocellular carcinogenesis and its prevention.
Intervirology 2005;48(1):29-38.
2004: Hiromi Ooga; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Junko Satoh; Hiromitsu Kumada
Efficacy of lamivudine treatment in Japanese patients with hepatitis B virus-related cirrhosis.
Journal of gastroenterology 2004;39(11):1078-84.
2004: Fumitaka Suzuki; Yasuji Arase; Norio Akuta; Akihito Tsubota; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Marie Matsuda; Junko Satoh; Hiromitsu Kumada
Efficacy of 6-month interferon therapy in chronic hepatitis B virus infection in Japan.
Journal of gastroenterology 2004;39(10):969-74.
2004: Hitomi Sezaki; Mariko Kobayashi; Tetsuya Hosaka; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Kimiko Takagi; Junko Sato; Hiromitsu Kumada
Hepatocellular carcinoma in noncirrhotic young adult patients with chronic hepatitis B viral infection.
Journal of gastroenterology 2004;39(6):550-6.
2004: Akihito Tsubota; Yasuji Arase; Fumitaka Suzuki; Mariko Kobayashi; Marie Matsuda; Junko Sato; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Severe acute exacerbation of liver disease may reduce or delay emergence of YMDD motif mutants in long-term lamivudine therapy for hepatitis B e antigen-positive chronic hepatitis B.
Journal of medical virology 2004;73(1):7-12.
2004: Tetsuya Hosaka; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Hitomi Sezaki; Norio Akuta; Akihito Tsubota; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.
Intervirology 2004;47(6):362-9.
2004: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Interferon therapy for 2 years or longer reduces the incidence of hepatocarcinogenesis in patients with chronic hepatitis C viral infection.
Intervirology 2004;47(6):355-61.
2004: Yasuji Arase; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Masahiro Kobayashi; Hitomi Sezaki; Kenji Ikeda; Hiromitsu Kumada
Sustained negativity for HCV-RNA over 24 or more months by long-term interferon therapy correlates with eradication of HCV in patients with hepatitis C virus genotype 1b and high viral load.
Intervirology 2004;47(1):19-25.
2003: Hitomi Sezaki; Yasuji Arase; Akihito Tsubota; Yoshiyuki Suzuki; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Kenji Ikeda; Hiromitsu Kumada
Type C-chronic hepatitis patients who had autoimmune phenomenon and developed jaundice during interferon therapy.
Journal of gastroenterology 2003;38(5):493-500.