FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Joseph Shaddock

Research Profile

Chemicals & Drugs

Procedures

Physiology

Living Beings

Anatomy

Disorders

Loss of Heterozygosity

Concepts & Ideas

Drug Dose Response Relationship

Co-author Network

Publications

TOP 3
Javed Bhalli; Wei Ding; Vasily N Dobrovolsky; Mason G Pearce; Joseph G Shaddock; Robert H Heflich
Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, Aristolochic acids.
Wei Ding; Daniel R Doerge; Anane Aidoo; Michelle E Bishop; Ching-Wei Chang; John R Latendresse; Mugimane G Manjanatha; Lea P McDaniel; Roberta A Mittelstaedt; Suzanne M Morris; Levan Muskhelishvili; Mason G Pearce; Dayton M Petibone; Joseph G Shaddock; Gene A White; Robert H Heflich
In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
L Patrice McDaniel; Roberta A Mittelstaedt; Joseph G Shaddock; Wei Ding; Vasily N Dobrovolsky; Daniel R Doerge; Robert H Heflich
Genotoxicity of furan in Big Blue rats.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Joseph Shaddock (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Javed Bhalli; Wei Ding; Vasily N Dobrovolsky; Mason G Pearce; Joseph G Shaddock; Robert H Heflich
Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, Aristolochic acids.
Mutation research 2013;753(2):82-92.
2012: Wei Ding; Daniel R Doerge; Anane Aidoo; Michelle E Bishop; Ching-Wei Chang; John R Latendresse; Mugimane G Manjanatha; Lea P McDaniel; Roberta A Mittelstaedt; Suzanne M Morris; Levan Muskhelishvili; Mason G Pearce; Dayton M Petibone; Joseph G Shaddock; Gene A White; Robert H Heflich
In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
Toxicology and applied pharmacology 2012;261(2):164-71.
2012: L Patrice McDaniel; Roberta A Mittelstaedt; Joseph G Shaddock; Wei Ding; Vasily N Dobrovolsky; Daniel R Doerge; Robert H Heflich
Genotoxicity of furan in Big Blue rats.
Mutation research 2012;742(1-2):72-8.
2011: Javed Bhalli; Xuefei Cao; Vasily N Dobrovolsky; Robert H Heflich; Mason G Pearce; Joseph G Shaddock; Hans-Werner Vohr
Report on stage III Pig-a mutation assays using benzo[a]pyrene.
Environmental and molecular mutagenesis 2011;52(9):731-7.
2011: Rahat Ali; Roberta A Mittelstaedt; Joseph G Shaddock; Wei Ding; Javed Bhalli; Qaiser M Khan; Robert H Heflich
Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines.
Mutation research 2011;723(1):58-64.
2010: Nan Mei; Lea P McDaniel; Vasily N Dobrovolsky; Xiaoqing Guo; Joseph G Shaddock; Roberta A Mittelstaedt; Mizuo Azuma; Sharon D Shelton; Lynda J McGarrity; Daniel R Doerge; Robert H Heflich
The genotoxicity of acrylamide and glycidamide in big blue rats.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(2):412-21.
2009: Mugimane G Manjanatha; Sharon D Shelton; Vasily N Dobrovolsky; Joseph G Shaddock; Lynda G McGarrity; Nathan W Twaddle; Martha M Moore; Donald R Mattison; William Slikker; Suzanne M Morris
Evaluation of mutagenic mode of action in Big Blue mice fed methylphenidate for 24 weeks.
Mutation research 2009;680(1-2):43-8.
2009: Linda S Von Tungeln; Mona I Churchwell; Daniel R Doerge; Joseph G Shaddock; Lynda J McGarrity; Robert H Heflich; Gonçalo Gamboa da Costa; M Matilde Marques; Frederick A Beland
DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide.
International journal of cancer. Journal international du cancer 2009;124(9):2006-15.
2009: Suzanne M Morris; Vasily N Dobrovolsky; Joseph G Shaddock; Roberta A Mittelstaedt; Michelle E Bishop; Mugimane G Manjanatha; Sharon D Shelton; Daniel R Doerge; Nathan C Twaddle; James J Chen; Chien-Ju Lin; Merle Paule; William Slikker; Charlotte E Hotchkiss; Dayton Petibone; James Tucker; Donald R Mattison
The genetic toxicology of methylphenidate hydrochloride in non-human primates.
Mutation research 2009;673(1):59-66.
2009: Vasily N Dobrovolsky; Joseph G Shaddock; Roberta A Mittelstaedt; Mugimane G Manjanatha; Daishiro Miura; Makoto Uchikawa; Donald R Mattison; Suzanne M Morris
Evaluation of Macaca mulatta as a model for genotoxicity studies.
Mutation research 2009;673(1):21-8.
2008: Mugimane G Manjanatha; Sharon D Shelton; Vasily N Dobrovolsky; Joseph G Shaddock; Lynda G McGarrity; Daniel R Doerge; Nathan W Twaddle; Chien-Ju Lin; James J Chen; Donald R Mattison; Suzanne M Morris
Pharmacokinetics, dose-range, and mutagenicity studies of methylphenidate hydrochloride in B6C3F1 mice.
Environmental and molecular mutagenesis 2008;49(8):585-93.
2008: Carrie R Valentine; Heather F Rainey; Jessica M Farrell; Joseph G Shaddock; Vasily N Dobrovolsky; Robert R Delongchamp
Frequency and spectrum of ENU-induced mutation in the Phi X174 transgene in mouse splenic lymphocytes and their significance to spontaneous transgenic rodent mutation frequencies.
Mutagenesis 2008;23(5):383-97.
2007: Sachin V Bendre; Joseph G Shaddock; Vasily N Dobrovolsky; Richard J Albertini; Robert H Heflich
Effect of chronic azathioprine treatment on germ-line transmission of Hprt mutation in mice.
Environmental and molecular mutagenesis 2007;48(9):744-53.
2007: Vasily N Dobrovolsky; Joseph G Shaddock; Roberta A Mittelstaedt; Michelle E Bishop; Sherry M Lewis; Fei W Lee; Anane Aidoo; Julian E A Leakey; June K Dunnick; Robert H Heflich
Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.
Environmental and molecular mutagenesis 2007;48(3-4):270-82.
2007: Linda S Von Tungeln; Lee D Williams; Daniel R Doerge; Joseph G Shaddock; Lynda J McGarrity; Suzanne M Morris; Roberta A Mittelstaedt; Robert H Heflich; Frederick A Beland
Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.
Environmental and molecular mutagenesis 2007;48(3-4):258-69.
2006: Joseph G Shaddock; Vasily N Dobrovolsky; Roberta A Mittelstaedt; Robert H Heflich; Barbara L Parsons
Frequency and types of spontaneous Hprt lymphocyte mutations in Pms2-deficient mice.
Mutation research 2006;595(1-2):69-79.
2005: Sachin V Bendre; Joseph G Shaddock; Ralph E Patton; Vasily N Dobrovolsky; Richard J Albertini; Robert H Heflich
Lymphocyte Hprt mutant frequency and sperm toxicity in C57BL/6 mice treated chronically with Azathioprine.
Mutation research 2005;578(1-2):1-14.
2005: Vasily N Dobrovolsky; Joseph G Shaddock; Robert H Heflich
Analysis of in vivo mutation in the hprt and tk genes of mouse lymphocytes.
Methods in molecular biology (Clifton, N.J.) 2005;291():133-44.
2004: Roberta A Mittelstaedt; Nan Mei; Peggy J Webb; Joseph G Shaddock; Vasily N Dobrovolsky; Lynda J McGarrity; Suzanne M Morris; Tao Chen; Frederick A Beland; Kevin J Greenlees; Robert H Heflich
Genotoxicity of malachite green and leucomalachite green in female Big Blue B6C3F1 mice.
Mutation research 2004;561(1-2):127-38.
2004: Linda S Von Tungeln; Vasily N Dobrovolsky; Michelle E Bishop; Joseph G Shaddock; Robert H Heflich; Frederick A Beland
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine.
Mutagenesis 2004;19(4):307-11.
2004: Roberta A Mittelstaedt; Linda S Von Tungeln; Joseph G Shaddock; Vasily N Dobrovolsky; Frederick A Beland; Robert H Heflich
Analysis of mutations in the Tk gene of Tk(+/-) mice treated as neonates with 3'-azido-3'-deoxythymidine (AZT).
Mutation research 2004;547(1-2):63-9.
2004: Mugimane G Manjanatha; Sharon D Shelton; M Bishop; Joseph G Shaddock; Vasily N Dobrovolsky; Robert H Heflich; Peggy J Webb; Lonnie R Blankenship; Frederick A Beland; Kevin J Greenlees; Sandra J Culp
Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green.
Mutation research 2004;547(1-2):5-18.
2004: Wolfgang W Huber; Candee H Teitel; Brian F Coles; Roberta S King; Frederick W Wiese; Keith R Kaderlik; Daniel A Casciano; Joseph G Shaddock; Gerard J Mulder; Kenneth F Ilett; Fred F Kadlubar
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Environmental and molecular mutagenesis 2004;44(4):265-76.
2004: Carrie R Valentine; Jessica L Raney; Joseph G Shaddock; Vasily N Dobrovolsky; Robert R Delongchamp
In vivo mutation in gene A of splenic lymphocytes from phiX174 transgenic mice.
Environmental and molecular mutagenesis 2004;44(2):128-50.
2003: Vasily N Dobrovolsky; Page B McKinzie; Joseph G Shaddock; Roberta A Mittelstaedt; Robert H Heflich; Barbara L Parsons
Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk(+/-) transgenic mice.
Mutagenesis 2003;18(4):365-70.
2002: Linda S Von Tungeln; L Patrice Hamilton; Vasily N Dobrovolsky; Michelle E Bishop; Joseph G Shaddock; Robert H Heflich; Frederick A Beland
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine.
Carcinogenesis 2002;23(9):1427-32.
2002: Vasily N Dobrovolsky; Joseph G Shaddock; Robert H Heflich
Mutagenicity of gamma-radiation, mitomycin C, and etoposide in the Hprt and Tk genes of Tk(+/-) mice.
Environmental and molecular mutagenesis 2002;39(4):342-7.
2001: Suzanne M Morris; JL Pipkin; WG Hinson; Joseph G Shaddock; William H Tolleson; John F Young; Daniel A Casciano
Decreased in vitro interaction between p53 and nuclear stress proteins in the p53-deficient mouse.
Electrophoresis 2001;22(10):2092-7.
2001: Deborah K Hansen; James B LaBorde; Kelly S Wall; WG Hinson; JL Pipkin; Joseph G Shaddock; Lascelles E Lyn-Cook; John F Young
Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(1):31-41.
2000: Vasily N Dobrovolsky; Joseph G Shaddock; Robert H Heflich
7,12-dimethylbenz[a]anthracene-induced mutation in the Tk gene of Tk(+/-) mice: automated scoring of lymphocyte clones using a fluorescent viability indicator.
Environmental and molecular mutagenesis 2000;36(4):283-91.
1999: Roberta S King; Candee H Teitel; Joseph G Shaddock; Daniel A Casciano; Fred F Kadlubar
Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative.
Cancer letters 1999;143(2):167-71.
1999: JL Pipkin; WG Hinson; John F Young; K L Rowland; Joseph G Shaddock; William H Tolleson; Peter H Duffy; Daniel A Casciano
Induction of stress proteins by electromagnetic fields in cultured HL-60 cells.
Bioelectromagnetics 1999;20(6):347-57.
1999: JL Pipkin; WG Hinson; S J James; Joseph G Shaddock; Lascelles E Lyn-Cook; Ritchie J Feuers; Suzanne M Morris; William H Tolleson; Daniel A Casciano
The relationship of p53 and stress proteins in response to bleomycin and retinoic acid in the p53 heterozygous mouse.
Biochimica et biophysica acta 1999;1450(2):164-76.
1998: Angela J Harris; Joseph G Shaddock; Mugimane G Manjanatha; J A Lisenbey; Daniel A Casciano
Identification of differentially expressed genes in aflatoxin B1-treated cultured primary rat hepatocytes and Fischer 344 rats.
Carcinogenesis 1998;19(8):1451-8.
1997: JL Pipkin; WG Hinson; S J James; Lascelles E Lyn-Cook; Peter H Duffy; Ritchie J Feuers; Joseph G Shaddock; K B Aly; Ronald W Hart; Daniel A Casciano
P53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration.
Mechanisms of ageing and development 1997;97(1):15-34.
1996: Mugimane G Manjanatha; J B Chen; Joseph G Shaddock; A J Harris; Sharon D Shelton; Daniel A Casciano
Molecular analysis of lacI mutations in Rat2 cells exposed to 7,12-dimethylbenz[a]anthracene: evidence for DNA sequence and DNA strand biases for mutation.
Mutation research 1996;372(1):53-64.
1996: Joseph G Shaddock; Ming W Chou; Daniel A Casciano
Effects of age and caloric restriction on cell proliferation in hepatocyte cultures from control and hepatectomized Fischer 344 rats.
Mutagenesis 1996;11(3):281-4.
1995: Joseph G Shaddock; Ritchie J Feuers; Ming W Chou; D H Swenson; Daniel A Casciano
Genotoxicity of tacrine in primary hepatocytes isolated from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats.
Mutation research 1995;344(1-2):79-88.
1995: Ming W Chou; Joseph G Shaddock; J Kong; Ronald W Hart; Daniel A Casciano
Effect of dietary restriction on partial hepatectomy-induced liver regeneration of aged F344 rats.
Cancer letters 1995;91(2):191-7.
1993: Joseph G Shaddock; Ritchie J Feuers; Ming W Chou; Daniel A Casciano
Evidence that DNA repair may not be modified by age or chronic caloric restriction.
Mutation research 1993;301(4):261-6.
1993: Joseph G Shaddock; Ritchie J Feuers; Ming W Chou; R A Pegram; Daniel A Casciano
Effects of aging and caloric restriction on the genotoxicity of four carcinogens in the in vitro rat hepatocyte/DNA repair assay.
Mutation research 1993;295(1):19-30.
1992: D W Kelly; C Lee Holder; W A Korfmacher; T A Getek; Jackson Lay; Daniel A Casciano; Joseph G Shaddock; H M Duhart; William Slikker
Metabolism of methapyrilene by Fischer-344 rat and B6C3F1 mouse hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(12):1367-81.
1991: Ming W Chou; R A Pegram; P Gao; S R Hansard; Joseph G Shaddock; Daniel A Casciano
The effects of dietary restriction and aging on in vivo and in vitro binding of aflatoxin B1 to cellular DNA.
Biomedical and environmental sciences : BES 1991;4(1-2):134-43.
1989: Joseph G Shaddock; Robert H Heflich; David C McMillan; Jack A Hinson; Daniel A Casciano
Pretreatment with mixed-function oxidase inducers increases the sensitivity of the hepatocyte/DNA repair assay.
Environmental and molecular mutagenesis 1989;13(4):281-8.
1988: David C McMillan; Joseph G Shaddock; Robert H Heflich; Daniel A Casciano; Jack A Hinson
Evaluation of propanil and its N-oxidized derivatives for genotoxicity in the Salmonella typhimurium reversion, Chinese hamster ovary/hypoxanthine guanine phosphoribosyl transferase, and rat hepatocyte/DNA repair assays.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1988;11(3):429-39.
1988: J D Budroe; H M Schol; Joseph G Shaddock; Daniel A Casciano
Inhibition of 7,12-dimethylbenz[a]anthracene-induced genotoxicity in Chinese hamster ovary cells by retinol and retinoic acid.
Carcinogenesis 1988;9(7):1307-11.
1987: J D Budroe; Joseph G Shaddock; Daniel A Casciano
Modulation of ultraviolet light-, ethyl methanesulfonate-, and 7,12-dimethylbenz[a]anthracene-induced unscheduled DNA synthesis by retinol and retinoic acid in the primary rat hepatocyte.
Environmental and molecular mutagenesis 1987;10(2):129-39.
1984: J D Budroe; Joseph G Shaddock; Daniel A Casciano
A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocyte/DNA repair assay.
Mutation research 1984;135(2):131-7.