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Naeem Shafqat

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Naeem Shafqat; Frank von Delft; Joao R C Muniz; Udo Oppermann; Evangelos Papagrigoriou; Ewa S Pilka; Wyatt W Yue
Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.
Apirat Chaikuad; Anthony R Clarke; Jan Frayne; Udo Oppermann; Naeem Shafqat; Ruby Al-Mokhtar; R Leo Brady; Gus Cameron; Wyatt W Yue
Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.
Anton Simeonov; Adam Yasgar; Carleen Klumpp; Wei Zheng; Naeem Shafqat; Udo Oppermann; Christopher P Austin; James Inglese
Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification.

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All Publications

2013: Naeem Shafqat; Frank von Delft; Joao R C Muniz; Udo Oppermann; Evangelos Papagrigoriou; Ewa S Pilka; Wyatt W Yue
Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.
The Biochemical journal 2013;452(1):27-36.
2011: Apirat Chaikuad; Anthony R Clarke; Jan Frayne; Udo Oppermann; Naeem Shafqat; Ruby Al-Mokhtar; R Leo Brady; Gus Cameron; Wyatt W Yue
Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.
The Biochemical journal 2011;435(2):401-9.
2007: Anton Simeonov; Adam Yasgar; Carleen Klumpp; Wei Zheng; Naeem Shafqat; Udo Oppermann; Christopher P Austin; James Inglese
Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification.
Assay and drug development technologies 2007;5(6):815-24.
2006: Naeem Shafqat; Jawed Shafqat; G Eissner; Hanns-Ulrich Marschall; K Tryggvason; U Eriksson; F Gabrielli; H Lardy; Hans Jörnvall; Udo Oppermann
Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.
Cellular and molecular life sciences : CMLS 2006;63(10):1205-13.
2006: Malin Hult; Naeem Shafqat; Björn Elleby; Doreen Mitschke; Stefan Svensson; Margareta Forsgren; Tjeerd Barf; Jerk Vallgårda; Lars Abrahmsen; Udo Oppermann
Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
Molecular and cellular endocrinology 2006;248(1-2):26-33.
2004: Malin Hult; Björn Elleby; Naeem Shafqat; Stefan Svensson; A Rane; Hans Jörnvall; Lars Abrahmsen; Udo Oppermann
Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism.
Cellular and molecular life sciences : CMLS 2004;61(7-8):992-9.
2003: Naeem Shafqat; Hanns-Ulrich Marschall; Charlotta Filling; erik Nordling; Xiao-Qiu Wu; Lars Björk; Johan Thyberg; Eva Mårtensson; Samina Salim; Hans Jörnvall; Udo Oppermann
Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD.
The Biochemical journal 2003;376(Pt 1):49-60.
2003: Udo Oppermann; Charlotta Filling; Malin Hult; Naeem Shafqat; Xiaoqiu Wu; Monica Lindh; Jawed Shafqat; erik Nordling; Yvonne Kallberg; Bengt Persson; Hans Jörnvall
Short-chain dehydrogenases/reductases (SDR): the 2002 update.
Chemico-biological interactions 2003;143-144():247-53.
2003: Naeem Shafqat; Björn Elleby; Stefan Svensson; Jawed Shafqat; Hans Jörnvall; Lars Abrahmsen; Udo Oppermann
Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species.
The Journal of biological chemistry 2003;278(3):2030-5.
2001: Charlotta Filling; Xiaoqiu Wu; Naeem Shafqat; Malin Hult; Eva Mårtensson; Jawed Shafqat; Udo Oppermann
Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases.
Molecular and cellular endocrinology 2001;171(1-2):99-101.