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Kashmira Shah

Research Profile

Chemicals & Drugs

Living Beings

Concepts & Ideas

Anatomy

T-Lymphocytes

Physiology

Ion Channel Gating

Disorders

Genes & Molecular Sequences

Molecular Structure

Procedures

Combinatorial Chemistry Techniques

Co-author Network

Publications

TOP 3
David R Bauman; Lisa C Contino; Jisong Cui; Margarita Garcia-Calvo; Xin Gu; Nancy Kevin; Xiuying Ma; Joe Metzger; Lee-Yuh Pai; Kashmira Shah; Xiaolan Shen; Diane E Shevell; Sloan Stribling; Alan Whitehead; Hratch J Zokian; Sherman T Waddell
Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension.
Milana Maletic; Aaron Leeman; Michael Szymonifka; Steven S Mundt; Hratch J Zokian; Kashmira Shah; Jasminka Dragovic; Kathy Lyons; Rolf Thieringer; Anne H Vosatka; James M Balkovec; Sherman Waddell
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome.
Wanying Sun; Milana Maletic; Steven S Mundt; Kashmira Shah; Hratch Zokian; Kathy Lyons; Sherman T Waddell; James M Balkovec
Substituted phenyl triazoles as selective inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1.

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All Publications

2013: David R Bauman; Lisa C Contino; Jisong Cui; Margarita Garcia-Calvo; Xin Gu; Nancy Kevin; Xiuying Ma; Joe Metzger; Lee-Yuh Pai; Kashmira Shah; Xiaolan Shen; Diane E Shevell; Sloan Stribling; Alan Whitehead; Hratch J Zokian; Sherman T Waddell
Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension.
Bioorganic & medicinal chemistry letters 2013;23(12):3650-3.
2011: Milana Maletic; Aaron Leeman; Michael Szymonifka; Steven S Mundt; Hratch J Zokian; Kashmira Shah; Jasminka Dragovic; Kathy Lyons; Rolf Thieringer; Anne H Vosatka; James M Balkovec; Sherman Waddell
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome.
Bioorganic & medicinal chemistry letters 2011;21(8):2568-72.
2011: Wanying Sun; Milana Maletic; Steven S Mundt; Kashmira Shah; Hratch Zokian; Kathy Lyons; Sherman T Waddell; James M Balkovec
Substituted phenyl triazoles as selective inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1.
Bioorganic & medicinal chemistry letters 2011;21(7):2141-5.
2010: Xia Yang; Larry Peterson; Rolf Thieringer; Joshua L Deignan; Xuping Wang; Jun Zhu; Susanna Wang; Hua Zhong; Serguei Stepaniants; John Beaulaurier; I-Ming Wang; Ray Rosa; Anne-Marie Cumiskey; Jane Ming-Juan Luo; Qi Luo; Kashmira Shah; Jianying Xiao; David Nickle; Andrew Plump; Eric E Schadt; Aldons J Lusis; Pek Yee Lum
Identification and validation of genes affecting aortic lesions in mice.
The Journal of clinical investigation 2010;120(7):2414-22.
2009: Gregory O Voronin; William P Porter; L Alexandra Wickham; Cesaire L Gai; Cordelia G Rasa; Sarah H West; Kashmira Shah
Use of a rigid endoscope to teach urethral catheterization of the female dog.
Lab animal 2009;38(8):271-4.
2008: Yuping Zhu; Steven H Olson; Donald Graham; Gool Patel; Anne Hermanowski-Vosatka; Steven S Mundt; Kashmira Shah; Marty Springer; Rolf Thieringer; Samuel Wright; Jianying Xiao; Hratch Zokian; Jasminka Dragovic; James M Balkovec
Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Bioorganic & medicinal chemistry letters 2008;18(11):3412-6.
2008: Yuping Zhu; Steven H Olson; Anne Hermanowski-Vosatka; Steven S Mundt; Kashmira Shah; Marty Springer; Rolf Thieringer; Samuel Wright; Jianying Xiao; Hratch Zokian; James M Balkovec
4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Bioorganic & medicinal chemistry letters 2008;18(11):3405-11.
2008: Susan D Aster; Donald W Graham; Divya Kharbanda; Gool Patel; Mitree Ponpipom; Gina M Santorelli; Michael J Szymonifka; Steven S Mundt; Kashmira Shah; Martin S Springer; Rolf Thieringer; Anne Hermanowski-Vosatka; Samuel D Wright; Jianying Xiao; Hratch Zokian; James M Balkovec
Bis-aryl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Bioorganic & medicinal chemistry letters 2008;18(9):2799-804.
2007: Ramon E Camacho; Richard Wnek; Paul Fischer; Kashmira Shah; Dennis Zaller; Andrea Woods; Nicola La Monica; Luigi Aurisicchio; Patricia Fitzgerald-Bocarsly; Gloria C Koo
Characterization of the NOD/scid-[Tg]DR1 mouse expressing HLA-DRB1*01 transgene: a model of SCID-hu mouse for vaccine development.
Experimental hematology 2007;35(8):1219-30.
2005: Xin Gu; Jasminka Dragovic; Gloria C Koo; Sam L Koprak; Cheryl LeGrand; Steven S Mundt; Kashmira Shah; Martin S Springer; Eugene Y Tan; Rolf Thieringer; Anne Hermanowski-Vosatka; Hratch J Zokian; James M Balkovec; Sherman T Waddell
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11beta-HSD1: novel therapeutic agents for the treatment of metabolic syndrome.
Bioorganic & medicinal chemistry letters 2005;15(23):5266-9.
2005: Anne Hermanowski-Vosatka; James M Balkovec; Kang Cheng; Howard Y Chen; Melba Hernandez; Gloria C Koo; Cheryl B Le Grand; Zhihua Li; Joseph M Metzger; Steven S Mundt; Heather Noonan; Christian N Nunes; Steven H Olson; Bill Pikounis; Ning Ren; Nancy Robertson; James M Schaeffer; Kashmira Shah; Martin S Springer; Alison M Strack; Matthias Strowski; Kenneth Wu; Tsueiju Wu; Jianying Xiao; Bei B Zhang; Samuel D Wright; Rolf Thieringer
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.
The Journal of experimental medicine 2005;202(4):517-27.
2005: Jianming Bao; Shouwu Miao; Frank Kayser; Andrew Kotliar; Robert K Baker; George A Doss; John P Felix; Randal M Bugianesi; Robert S Slaughter; Gregory J Kaczorowski; Maria L Garcia; Sookhee N Ha; Laurie A Castonguay; Gloria C Koo; Kashmira Shah; Martin S Springer; Mary Jo Staruch; William H Parsons; Kathleen M Rupprecht
Potent Kv1.3 inhibitors from correolide-modification of the C18 position.
Bioorganic & medicinal chemistry letters 2005;15(2):447-51.
2004: Ramon E Camacho; Richard Wnek; Kashmira Shah; Dennis Zaller; Richard J O'Reilly; Nancy Collins; Patricia Fitzgerald-Bocarsly; Gloria C Koo
Intra-thymic/splenic engraftment of human T cells in HLA-DR1 transgenic NOD/scid mice.
Cellular immunology 2004;232(1-2):86-95.
2003: George A Doherty; Ginger X Yang; Edite Borges; Sharon Tong; Ermengilda McCauley; Kelly M Treonz; Gail Van Riper; Stephen G Pacholok; Qian Si; Gloria C Koo; Kashmira Shah; Richard A Mumford; William K Hagmann
N-isonicotinoyl-(L)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists.
Bioorganic & medicinal chemistry letters 2003;13(11):1891-5.
2003: Gloria C Koo; Kashmira Shah; Gloria J F Ding; Jianying Xiao; Richard Wnek; George Doherty; Xin Chun Tong; R Blake Pepinsky; Ko-Chung Lin; William K Hagmann; Douglas W Kawka; Irwin I Singer
A small molecule very late antigen-4 antagonist can inhibit ovalbumin-induced lung inflammation.
American journal of respiratory and critical care medicine 2003;167(10):1400-9.
2003: Shouwu Miao; Jianming Bao; Maria L Garcia; Joung L Goulet; Xingfang J Hong; Gregory J Kaczorowski; Frank Kayser; Gloria C Koo; Andrew Kotliar; william Schmalhofer; Kashmira Shah; Peter J Sinclair; Robert S Slaughter; Martin S Springer; Mary Jo Staruch; Nancy N Tsou; Frederick Wong; William H Parsons; Kathleen M Rupprecht
Benzamide derivatives as blockers of Kv1.3 ion channel.
Bioorganic & medicinal chemistry letters 2003;13(6):1161-4.
2003: Kashmira Shah; J Tom Blake; Christopher Huang; Paul Fischer; Gloria C Koo
Immunosuppressive effects of a Kv1.3 inhibitor.
Cellular immunology 2003;221(2):100-6.
1999: Gloria C Koo; JT Blake; Kashmira Shah; Mary Jo Staruch; Francis J Dumont; Denise Wunderler; Manuel Sanchez; Owen B McManus; A Sirotina-Meisher; P Fischer; R C Boltz; Michael A Goetz; R Baker; Jianming Bao; Frank Kayser; Kathleen M Rupprecht; William H Parsons; X C Tong; I E Ita; James V Pivnichny; S Vincent; P Cunningham; Donald F Hora; William P Feeney; Gregory J Kaczorowski
Correolide and derivatives are novel immunosuppressants blocking the lymphocyte Kv1.3 potassium channels.
Cellular immunology 1999;197(2):99-107.
1997: Gloria C Koo; JT Blake; A Talento; M Nguyen; S Lin; A Sirotina; Kashmira Shah; K Mulvany; Donald F Hora; P Cunningham; Denise Wunderler; Owen B McManus; Robert S Slaughter; Randal M Bugianesi; J Felix; M Garcia; J Williamson; Gregory J Kaczorowski; NH Sigal; Martin S Springer; William P Feeney
Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5120-8.