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Kaj Blennow

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Gunnar Brinkmalm; Oskar Hansson; Francesco Lipari; Marc Mercken; Lennart Minthon; Ulf Andreasson; Maria Bjerke; Kaj Blennow; Philippe Bourgeois; Ann Brinkmalm; Annika Ohrfelt; Stéphane Parent; Rita Persson; Erik Portelius; Henrik Zetterberg; Magdalena Nutu
Soluble amyloid precursor protein α and β in CSF in Alzheimer's disease.
Kaj Blennow; Henrik Zetterberg
The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease.
Guido Alves; Ulf Andreasson; Mona Beyer; Kaj Blennow; Bastiaan R Bloem; George F Borm; Turi O Dalaker; Johannes Lange; Kenn Freddy Pedersen; Ole-Bjørn Tysnes; Henrik Zetterberg; Robert Zivadinov; Dag Aarsland; Jan Petter Larsen
Cerebrospinal fluid amyloid-β and phenotypic heterogeneity in de novo Parkinson's disease.

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All Publications

2013: Gunnar Brinkmalm; Oskar Hansson; Francesco Lipari; Marc Mercken; Lennart Minthon; Ulf Andreasson; Maria Bjerke; Kaj Blennow; Philippe Bourgeois; Ann Brinkmalm; Annika Ohrfelt; Stéphane Parent; Rita Persson; Erik Portelius; Henrik Zetterberg; Magdalena Nutu
Soluble amyloid precursor protein α and β in CSF in Alzheimer's disease.
Brain research 2013;1513():117-26.
2013: Kaj Blennow; Henrik Zetterberg
The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease.
The Medical clinics of North America 2013;97(3):369-76.
2013: Guido Alves; Ulf Andreasson; Mona Beyer; Kaj Blennow; Bastiaan R Bloem; George F Borm; Turi O Dalaker; Johannes Lange; Kenn Freddy Pedersen; Ole-Bjørn Tysnes; Henrik Zetterberg; Robert Zivadinov; Dag Aarsland; Jan Petter Larsen
Cerebrospinal fluid amyloid-β and phenotypic heterogeneity in de novo Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2013;84(5):537-43.
2013: I H G B Ramakers; Marcel Olde Rikkert; Philip scheltens; L M Shaw; Hilkka Soininen; Luiza Spiru; J Q Trojanowski; Marcel M Verbeek; F R J Verhey; Pieter Jelle Visser; Pauline Aalten; Kaj Blennow; Harald Hampel
Anxiety is related to Alzheimer cerebrospinal fluid markers in subjects with mild cognitive impairment.
Psychological medicine 2013;43(5):911-20.
2013: Anna Jeppsson; Kaj Blennow; Henrik Zetterberg; Carsten Wikkelsø
Idiopathic normal-pressure hydrocephalus: pathophysiology and diagnosis by CSF biomarkers.
Neurology 2013;80(15):1385-92.
2013: Steven T DeKosky; Kaj Blennow; Milos D Ikonomovic; Sam Gandy
Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers.
Nature reviews. Neurology 2013;9(4):192-200.
2013: Henrik Zetterberg; Douglas H Smith; Kaj Blennow
Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood.
Nature reviews. Neurology 2013;9(4):201-10.
2013: Hugo Marcel Vanderstichele; Manu Vandijck; Henrik Zetterberg; Kaj Blennow; Andreas Jeromin; Leslie Shaw; Charlotte Teunissen; Sebastiaan Engelborghs
Alzheimer disease biomarker testing in cerebrospinal fluid: a method to harmonize assay platforms in the absence of an absolute reference standard.
Clinical chemistry 2013;59(4):710-2.
2013: Bryan Krastins; Vathany Kulasingam; Kaj Blennow; Gregory Byram; Lewis Couchman; Benoit Coulombe; Bruno Darbouret; Alejandra Garces; Johan Gobom; Urban A Kiernan; Caje Moniz; Dobrin Nedelkov; Randall Nelson; Eric E Niederkofler; Josef Pannee; Joëlle R Pérusse; Scott Peterman; Erik Portelius; Amol Prakash; David A Sarracino; Nabil G Seidah; Jennifer N Sutton; Gouri Vadali; Maryann S Vogelsang; Mary F Lopez
Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum.
Clinical biochemistry 2013;46(6):399-410.
2013: Kristin Augutis; Markus Axelsson; Kaj Blennow; Gunnar Brinkmalm; Mikael K Gustavsson; Jan Lycke; Clas Malmeström; Erik Portelius; Henrik Zetterberg; Ulf Andreasson; Niklas Mattsson
Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2013;19(5):543-52.
2013: Margareta Jernås; Jan Lycke; Clas Malmeström; Intawat Nookaew; Caroline Olsson; Mats Rudemo; Hans Wadenvik; Henrik Zetterberg; Markus Axelsson; Kaj Blennow; Bob Olsson
MS risk genes are transcriptionally regulated in CSF leukocytes at relapse.
Multiple sclerosis (Houndmills, Basingstoke, England) 2013;19(4):403-10.
2013: Stephanie J B Vos; Lars-Olof Wahlund; Robin Wolz; Kaj Blennow; Giovanni B Frisoni; Lutz Froelich; Harald Hampel; Dirk L Knol; Lennart Minthon; Flavio Nobili; Philip scheltens; Hilkka Soininen; Magda Tsolaki; Wiesje van der Flier; Ineke A van Rossum; Frans Verhey; Pieter Jelle Visser
Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.
Neurology 2013;80(12):1124-32.
2013: Richard Dodel; Martin Farlow; Stefan Förster; Jerome Goldstein; Stefan Haag; Michael Jacoby; Judith Alferink; Piero Antuono; Jan-Philipp Bach; Frederik Barkhof; Peter Bartenstein; Kaj Blennow; Katharina Buerger; Isaac Melamed; Markus Otto; Julius Popp; Ralph Richter; Axel Rominger; James Stevens; Stefan Wietek; Jens Wiltfang; Yaroslav Winter; Frank Jessen
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial.
Lancet neurology 2013;12(3):233-43.
2013: Maria C Carrillo; Piotr Lewczuk; Niklas Mattsson; Pankaj Oberoi; Salvatore Salamone; Leslie M Shaw; Holly Soares; Diane Stephenson; Robert Umek; Manu Vandijck; Lisa Bain; Tobias Bittner; Kaj Blennow; Henrik Zetterberg
Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2013;9(2):137-40.
2013: Magdalena Nutu; Stéphane Parent; Erik Portelius; Henrik Zetterberg; Philippe Bourgeois; Radu Constantinescu; Sara Hall; Oskar Hansson; Francesco Lipari; Ulf Andreasson; Kaj Blennow
Aβ1-15/16 as a potential diagnostic marker in neurodegenerative diseases.
Neuromolecular medicine 2013;15(1):169-79.
2013: Joel Jakobsson; Carl Johan Ekman; Anette G M Johansson; Kaj Blennow; Henrik Zetterberg; Mikael Landén
Altered concentrations of amyloid precursor protein metabolites in the cerebrospinal fluid of patients with bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013;38(4):664-72.
2013: Jeffrey Randall; Sten Rubertsson; Henrik Zetterberg; Kaj Blennow; David C Duffy; David R Fournier; Erik Mörtberg; Gail K Provuncher; David H Wilson
Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: results of a pilot study.
Resuscitation 2013;84(3):351-6.
2013: Giovanni B Frisoni; Kaj Blennow
Biomarkers for Alzheimer's: the sequel of an original model.
Lancet neurology 2013;12(2):126-8.
2013: Jan Jessen Krut; Richard W Price; Marie Studahl; Henrik Zetterberg; Kaj Blennow; Paola Cinque; Lars Hagberg; Magnus Gisslen
Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections.
Journal of neurology 2013;260(2):620-6.
2013: Sanna Neselius; Jeffrey Randall; David Wilson; Henrik Zetterberg; Kaj Blennow; Jan Marcusson; Helena Brisby
Olympic boxing is associated with elevated levels of the neuronal protein tau in plasma.
Brain injury : [BI] 2013;27(4):425-33.
2013: Pashtun Shahim; Kaj Blennow; Andrea E Bochem; G Kees Hovingh; Ronald Lautner; Niklas Mattsson; Mohammad Mahdi Motazacker; Henrik Zetterberg
Plasma Amyloid-β in Patients with Tangier Disease.
Journal of Alzheimer's disease : JAD 2013;35(2):307-12.
2013: Annica Sjölander; Eugeen Vanmechelen; Kaj Blennow; Lennart Minthon; Lieve Nuytinck; Staffan Nilsson
Functional mannose-binding lectin haplotype variants are associated with Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;35(1):121-7.
2013: Jonny Daborg; Eric Hanse; Sandra Holmgren; Lennart Minthon; Staffan Nilsson; Marcela Pekna; Ingmar Skoog; Alexandra Abramsson; Ulf Andreasson; Kaj Blennow; Madeleine Zetterberg; Henrik Zetterberg
Complement gene single nucleotide polymorphisms and biomarker endophenotypes of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;35(1):51-7.
2013: Daniel Bremell; Mikael Edsbagge; Ulf Andreasson; Kaj Blennow; Niklas Mattsson; Carsten Wikkelsö; Henrik Zetterberg; Lars Hagberg
Cerebrospinal fluid CXCL13 in Lyme neuroborreliosis and asymptomatic HIV infection.
BMC neurology 2013;13():2.
2013: Bob Olsson; Henrik Zetterberg; Niels Andreasen; Peter Annas; Hans Basun; Kaj Blennow; Joakim Hertze; Kina Höglund; Lars Lannfelt; Lennart Minthon; Katarina Nägga; Mattias Ohlsson; Oskar Hansson
Cerebrospinal fluid levels of heart fatty acid binding protein are elevated prodromally in Alzheimer's disease and vascular dementia.
Journal of Alzheimer's disease : JAD 2013;34(3):673-9.
2013: Josef Pannee; Erik Portelius; Ingrid Zegers; Henrik Zetterberg; Oskar Hansson; Peter Höjrup; Martin Hornshaw; Lennart Minthon; Madalina Oppermann; Alan Atkins; Kaj Blennow; Johan Gobom
A selected reaction monitoring (SRM)-based method for absolute quantification of Aβ38, Aβ40, and Aβ42 in cerebrospinal fluid of Alzheimer's Disease patients and healthy controls.
Journal of Alzheimer's disease : JAD 2013;33(4):1021-32.
2013: B Reinsfelt; Anne Westerlind; H Zetterberg; Kaj Blennow; Sven-Erik Ricksten
Open-heart surgery increases cerebrospinal fluid levels of Alzheimer-associated amyloid β.
Acta anaesthesiologica Scandinavica 2013;57(1):82-8.
2013: Bob Olsson; Henrik Zetterberg; Niels Andreasen; Peter Annas; Hans Basun; Kaj Blennow; Joakim Hertze; Kina Höglund; Lars Lannfelt; Ronald Lautner; Lennart Minthon; Katarina Nägga; Oskar Hansson
Microglial markers are elevated in the prodromal phase of Alzheimer's disease and vascular dementia.
Journal of Alzheimer's disease : JAD 2013;33(1):45-53.
2013: Erik Portelius; Ulla Rüetschi; Ulf Andreasson; Kaj Blennow; Ann Brinkmalm; Gunnar Brinkmalm; Johan Gobom; Mikko Hölttä; Niklas Mattsson; Maria Olsson; Henrik Zetterberg
Mass spectrometric characterization of amyloid-β species in the 7PA2 cell model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33(1):85-93.
2013: Henrik Zetterberg; Kaj Blennow
Cerebrospinal fluid biomarkers for Alzheimer's disease: more to come?
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S361-9.
2012: Kaj Blennow; John Hardy; Henrik Zetterberg
The neuropathology and neurobiology of traumatic brain injury.
Neuron 2012;76(5):886-99.
2012: Niklas Mattsson; Maria Olsson; Charles Vite; Henrik Zetterberg; Ulf Andreasson; Kaj Blennow; Maria Blomqvist; Gunnar Brinkmalm; Johan Gobom; Mikael K Gustavsson; Caroline Hastings; Silva Hecimovic; Marko Kosicek; Martina Malnar; Jan-Eric Månsson; Erik Portelius
Amyloid-β metabolism in Niemann-Pick C disease models and patients.
Metabolic brain disease 2012;27(4):573-85.
2012: Sara Hall; Ulf Andreasson; Kaj Blennow; Frederick Bostrom; Radu Constantinescu; Hilde Decraemer; Widner Håkan; Björn Holmberg; Elisabet Londos; Lennart Minthon; Katarina Någga; Christer Nilsson; Annika Öhrfelt; Yulia Surova; Eugeen Vanmechelen; Henrik Zetterberg; Oskar Hansson
Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders.
Archives of neurology 2012;69(11):1445-52.
2012: Vladimir Coric; Randy Dockens; Howard H Feldman; Chahin Pachai; Gary Pilcher; Erik Portelius; Ralph W Richter; Linda Rollin; Stephen Salloway; Thomas Shiovitz; Holly Soares; Hilkka Soininen; Stephen Thein; Christopher H van Dyck; Charles Albright; Niels Andreasen; Ulf Andreasson; Kaj Blennow; Mark Brody; Susan Colby; Robert M Berman
Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease.
Archives of neurology 2012;69(11):1430-40.
2012: Connie Luk; Nadia Magdalinou; María José Martí; Brit Mollenhauer; Y A L Pijnenburg; Claudia Trenkwalder; John Van Swieten; David R Williams; Henrik Zetterberg; Kaj Blennow; Barbara Borroni; Ana Cámara; Perdita Cheshire; Wan Zheng Chiu; Yaroslau Compta; Radu Constantinescu; Geshanthi Hondhamuni; Andrew J Lees; Rohan de Silva
Development and assessment of sensitive immuno-PCR assays for the quantification of cerebrospinal fluid three- and four-repeat tau isoforms in tauopathies.
Journal of neurochemistry 2012;123(3):396-405.
2012: Ineke A van Rossum; Frans Verhey; Stephanie J B Vos; Lars-Olof Wahlund; Robin Wolz; Frederik Barkhof; Kaj Blennow; Leah Burns; Harald Hampel; Dirk L Knol; Gilbert L'italien; Lennart Minthon; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Charlotte E Teunissen; Magda Tsolaki; Wiesje M van der Flier; Pieter Jelle Visser
Injury markers predict time to dementia in subjects with MCI and amyloid pathology.
Neurology 2012;79(17):1809-16.
2012: Stephanie Vos; Lars-Olof Wahlund; Robin Wolz; Pauline Aalten; Frederik Barkhof; Kaj Blennow; Leah Burns; Harald Hampel; Ron Handels; Dirk Knol; Gilbert L'Italien; Lennart Minthon; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Charlotte E Teunissen; Magda Tsolaki; Wiesje van der Flier; Ineke van Rossum; Frans Verhey; Pieter Jelle Visser
Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI.
Neurobiology of aging 2012;33(10):2272-81.
2012: Johanna Wanngren; Henrik Zetterberg; Kaj Blennow; Jenny Blomqvist; Tomas Borgegård; Anders Juréus; Rebecka Klintenberg; Johan Lundkvist; jan ottervald; Santiago Parpal; Erik Portelius; Susanne Rosqvist; Kia Strömberg; Helena Karlström
Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production.
The Journal of biological chemistry 2012;287(39):32640-50.
2012: Kaj Blennow; Henrik Zetterberg; Anne M Fagan
Fluid biomarkers in Alzheimer disease.
Cold Spring Harbor perspectives in medicine 2012;2(9):a006221.
2012: Niklas Mattsson; Kevin Mills; Josef Pannee; Marianne Ratcliffe; Leslie M Shaw; Adam J Simon; Holly Soares; Charlotte E Teunissen; Robert M Umek; hugo vanderstichele; Marcel M Verbeek; Ingrid Zegers; Henrik Zetterberg; Ulf Andreasson; Maria Bjerke; Marinus A Blankenstein; Kaj Blennow; Robert Bowser; Maria C Carrillo; Johan Gobom; Theresa Heath; Rand Jenkins; Andreas Jeromin; June Kaplow; Daniel Kidd; Omar F Laterza; Andrew Lockhart; Michael P Lunn; Robert L Martone; Erik Portelius
Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42.
Biomarkers in medicine 2012;6(4):409-17.
2012: Niklas Mattsson; Staffan Persson; Leslie M Shaw; Ingrid Zegers; Henrik Zetterberg; Ulf Andreasson; Maria C Carrillo; Kaj Blennow
Proficiency testing programs for Alzheimer's disease cerebrospinal fluid biomarkers.
Biomarkers in medicine 2012;6(4):401-7.
2012: Jonathan W Bartlett; Kaj Blennow; Chris Frost; Niklas Mattsson; Tobias Skillbäck; Henrik Zetterberg; Jonathan M Schott
Determining cut-points for Alzheimer's disease biomarkers: statistical issues, methods and challenges.
Biomarkers in medicine 2012;6(4):391-400.
2012: Björn Reinsfelt; Sven-Erik Ricksten; Kaj Blennow; Johan Fredén-Lindqvist; Henrik Zetterberg; Anne Westerlind
Cerebrospinal fluid markers of brain injury, inflammation, and blood-brain barrier dysfunction in cardiac surgery.
The Annals of thoracic surgery 2012;94(2):549-55.
2012: Kaj Blennow; Michael Grundman; Enchi Liu; Juha O Rinne; Stephen Salloway; Jenny Wei; Henrik Zetterberg; Ronald Black
Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease.
Archives of neurology 2012;69(8):1002-10.
2012: Michael Ewers; Yetunde O Faluyi; Annette Fitzpatrick; Harald Hampel; Oskar Hansson; Lennart Minthon; Susanne Schmitz; Leslie M Shaw; Stefan J Teipel; John Q Trojanowski; Bruno Vellas; Cathal Walsh; Michael Weiner; David Bennett; Kaj Blennow; Katharina Buerger; Bruno Dubois
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Neurobiology of aging 2012;33(8):1599-608.
2012: Bengt Winblad; Niels Andreasen; Kaj Blennow; Thomas Dumortier; Annette Floesser; Georges Imbert; Joens Lundmark; R Paul Maguire; Lennart Minthon; Jean-Marc Orgogozo; Matthias Staufenbiel; Ana Graf
Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study.
Lancet neurology 2012;11(7):597-604.
2012: Sara Landgren; Jan Marcusson; Lennart Minthon; Staffan Nilsson; Mona Seibt Palmér; Ingmar Skoog; Malin von Otter; Anders Wallin; Henrik Zetterberg; Caroline Zetterström; Niels Andreasen; Kaj Blennow; Nenad Bogdanovic; Deborah R Gustafson; Petronella Kettunen
A novel ARC gene polymorphism is associated with reduced risk of Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2012;119(7):833-42.
2012: Marcin Kruczyk; Lennart Minthon; Sindre Rolstad; Anders Wallin; Henrik Zetterberg; Kaj Blennow; Oskar Hansson; Jan Komorowski; Mats Gunnar Andersson
Monte Carlo feature selection and rule-based models to predict Alzheimer's disease in mild cognitive impairment.
Journal of neural transmission (Vienna, Austria : 1996) 2012;119(7):821-31.
2012: Jonny Daborg; Eric Hanse; Oskar Hansson; Ronald Lautner; Lennart Minthon; Marcela Pekna; Ulf Andreasson; Kaj Blennow; Henrik Zetterberg
Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2012;119(7):789-97.
2012: Lidia Glodzik; Yi Li; Pauline McHugh; Pankaj Mehta; Lisa Mosconi; Elizabeth Pirraglia; Kenneth E Rich; Wai Hon Tsui; Schantel Williams; Henrik Zetterberg; Raymond Zinkowski; Fahad Ali; Kaj Blennow; Susan De Santi; Mony J de Leon
Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly.
Neurobiology of aging 2012;33(7):1215-27.
2012: Ingmar Skoog; Kaj Blennow; Sterling C Johnson; Pernille J Olesen; Bo Palmertz; Erin D Bigler
Head size may modify the impact of white matter lesions on dementia.
Neurobiology of aging 2012;33(7):1186-93.
2012: Nunzio Pomara; Domenico Pratico'; Antero S Sarreal; John J Sidtis; Thomas M Wisniewski; Henrik Zetterberg; Davide Bruno; Raymundo T Hernando; Pankaj D Mehta; Jay Nierenberg; Eva Petkova; Kaj Blennow
Lower CSF amyloid beta peptides and higher F2-isoprostanes in cognitively intact elderly individuals with major depressive disorder.
The American journal of psychiatry 2012;169(5):523-30.
2012: Gunnar Brinkmalm; Johan Gobom; Mikael K Gustavsson; Adnan Halim; Göran Larson; Jan-Eric Månsson; Niklas Mattsson; Jonas Nilsson; Rita Persson; Erik Portelius; Ulla Rüetschi; Charles H Vite; Henrik Zetterberg; Annika Öhrfelt; Kaj Blennow; Ann Brinkmalm
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal fluid.
Journal of mass spectrometry : JMS 2012;47(5):591-603.
2012: Davide Bruno; Michael W Lutz; Jay Nierenberg; Nunzio Pomara; James C Ritchie; Henrik Zetterberg; Kaj Blennow
Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants.
Experimental gerontology 2012;47(5):347-52.
2012: Ulf Andreasson; Josef Pannee; Erik Portelius; Henrik Zetterberg; Kaj Blennow
Multiplexing and multivariate analysis in neurodegeneration.
Methods (San Diego, Calif.) 2012;56(4):464-70.
2012: Jessica L Wittnam; Henrik Zetterberg; Kaj Blennow; Hans-Ulrich Demuth; Mikael K Gustavsson; Birgit Koch; Erik Portelius; Stephan Schilling; Oliver Wirths; Thomas A Bayer
Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease.
The Journal of biological chemistry 2012;287(11):8154-62.
2012: Christoffer Rosén; Niels Andreasen; Ulf Andreasson; Kaj Blennow; Jan Marcusson; Niklas Mattsson; Lennart Minthon; Henrik Zetterberg
Cerebrospinal fluid profiles of amyloid β-related biomarkers in Alzheimer's disease.
Neuromolecular medicine 2012;14(1):65-73.
2012: Sofia Movérare-Skrtic; Anders Wallin; Henrik Zetterberg; Kaj Blennow; Oskar Hansson; Jan-Ove Johansson; Per Johansson; Niklas Mattsson; Johan Svensson
Leukocyte telomere length (LTL) is reduced in stable mild cognitive impairment but low LTL is not associated with conversion to Alzheimer's disease: a pilot study.
Experimental gerontology 2012;47(2):179-82.
2012: Anna Bredberg; Johan Gobom; Per Larsson; Ann-Charlotte Almstrand; Kaj Blennow; Anna-Carin Olin; Ekaterina Mirgorodskaya
Exhaled endogenous particles contain lung proteins.
Clinical chemistry 2012;58(2):431-40.
2012: Jaana Gustavsson; Karin Leander; Lauren Lissner; Kirsten Mehlig; Lena Björck; Kaj Blennow; Elisabeth Strandhagen; Dag Steinar Thelle; Henrik Zetterberg; Fredrik Nyberg
Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.
Atherosclerosis 2012;220(2):486-92.
2012: Niklas Mattsson; Forbes D Porter; Nicole M Yanjanin; Henrik Zetterberg; Simona Bianconi; Rao Fu; Jan-Eric Månsson; Kaj Blennow
Miglustat treatment may reduce cerebrospinal fluid levels of the axonal degeneration marker tau in niemann-pick type C.
JIMD reports 2012;3():45-52.
2012: Sara Bromander; Marianne Kristiansson; Henrik Anckarsäter; Rolf Anckarsäter; Kaj Blennow; Henrik Zetterberg; Caroline E Wass
Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study.
Journal of neuroinflammation 2012;9():242.
2012: Johan Mellergård; Bob Olsson; Anders Tisell; Kaj Blennow; Ida Blystad; Charlotte Dahle; Olof Dahlqvist Leinhard; Jan Ernerudh; Anne-Marie Landtblom; Peter Lundberg; Magnus Vrethem
Association between change in normal appearing white matter metabolites and intrathecal inflammation in natalizumab-treated multiple sclerosis.
PloS one 2012;7(9):e44739.
2012: Kina Höglund; Lars Lannfelt; Lennart Minthon; Peter Annas; Ali Aziz; Hans Basun; Kaj Blennow; Anna Bogstedt; Susanne Fabre; Niels Andreasen
Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;32(4):939-47.
2012: Michael Jonsson; Karin Lind; Leonardo Pantoni; Sindre Rolstad; Maria Bjerke; Kaj Blennow; Ake Edman; Alida A Gouw; Domenico Inzitari; Henrik Zetterberg; Anders Wallin
Low cerebrospinal fluid sulfatide predicts progression of white matter lesions: The LADIS study.
Dementia and geriatric cognitive disorders 2012;34(1):61-7.
2012: Mikko Hölttä; Niklas Mattsson; Ekaterina Mirgorodskaya; Henrik Zetterberg; Kaj Blennow; Johan Gobom
Peptidome analysis of cerebrospinal fluid by LC-MALDI MS.
PloS one 2012;7(8):e42555.
2012: Bob Olsson; Henrik Zetterberg; Kina Höglund; Lars Lannfelt; Clas Malmeström; Niels Andreasen; Peter Annas; Hans Basun; Kaj Blennow
Extreme stability of chitotriosidase in cerebrospinal fluid makes it a suitable marker for microglial activation in clinical trials.
Journal of Alzheimer's disease : JAD 2012;32(2):273-6.
2012: Anilkumar Pillai; Nunzio Pomara; Leslie A Saint-Louis; Antero S Sarreal; Henrik Zetterberg; Stephen D Ginsberg; Raymundo T Hernando; Pankaj D Mehta; Jay Nierenberg; Kaj Blennow; Davide Bruno; Peter F Buckley
Plasma BDNF levels vary in relation to body weight in females.
PloS one 2012;7(7):e39358.
2012: Sebastian Palmqvist; Carina Wattmo; Henrik Zetterberg; Kaj Blennow; Joakim Hertze; Elisabet Londos; Lennart Minthon; Ola Hansson
Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study.
PloS one 2012;7(6):e38639.
2012: Erik Stomrud; Henrik Zetterberg; Lennart Minthon; Erik Ryding; Kaj Blennow; Anton Forsberg; Douglas Hägerström; Oskar Hansson; Elisabet Londos
CSF biomarkers correlate with cerebral blood flow on SPECT in healthy elderly.
Dementia and geriatric cognitive disorders 2012;33(2-3):156-63.
2012: Barbara B Bendlin; Alex C Birdsill; Kaj Blennow; Cynthia M Carlsson; Sterling C Johnson; Ozioma C Okonkwo; Luigi Puglielli; Michele L Ries; Howard A Rowley; Andrew L Alexander; Sanjay Asthana; Aparna Sodhi; Auriel A Willette; Henrik Zetterberg; Mark A Sager
CSF T-Tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease.
PloS one 2012;7(6):e37720.
2012: Z Pernber; Kaj Blennow; Nenad Bogdanovic; Jan-Eric Månsson; M Blomqvist
Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2012;33(2-3):174-88.
2012: Erik Portelius; Eric Siemers; Wendy C Sigurdson; Henrik Zetterberg; Ulf Andreasson; Kaj Blennow; Philippe Bourgeois; Robert A Dean; David M Holtzman; Alexandre Marcil; Kwasi G Mawuenyega; Patrick C May; Magdalena Nutu; Steven M Paul; Randall J Bateman
Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;31(2):335-41.
2012: Sanna Neselius; Annette Theodorsson; Henrik Zetterberg; Kaj Blennow; Helena Brisby; Jan Marcusson
CSF-biomarkers in Olympic boxing: diagnosis and effects of repetitive head trauma.
PloS one 2012;7(4):e33606.
2012: Niklas Mattsson; Erik Portelius; Sindre Rolstad; Mats Stridsberg; Anders Wallin; Ulf Andreasson; Kaj Blennow; Mikael Gustavsson; Henrik Zetterberg
Longitudinal cerebrospinal fluid biomarkers over four years in mild cognitive impairment.
Journal of Alzheimer's disease : JAD 2012;30(4):767-78.
2012: Maria Eriksdotter-Jönhagen; Vesna Jelic; Ahmadul Kadir; Göran Lind; Bengt Linderoth; Agneta Nordberg; Ake Seiger; Erik Sundström; Layth Aladellie; Ove Almkvist; Per Almqvist; Niels Andreasen; Kaj Blennow; Nenad Bogdanovic; Lars-Olof Wahlund; Anders Wall; Maria Wiberg; Bengt Winblad; Lars Wahlberg
Encapsulated cell biodelivery of nerve growth factor to the Basal forebrain in patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 2012;33(1):18-28.
2012: Niklas Mattsson; Marc Mercken; Ulf Neumann; Maria Olsson; Ludovic Perrot; Lawrence Rajendran; Henrik Zetterberg; Ulf Andreasson; Kaj Blennow; Herman Borghys; Gunnar Brinkmalm; Deborah Dhuyvetter; Mikael Gustavsson; Laura H Jacobson; Fredrik Jeppsson; Johan Lundkvist; Erik Portelius
BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system.
PloS one 2012;7(2):e31084.
2012: Erik Portelius; Henrik Zetterberg; Ulf Andreasson; Mikael K Gustavsson; Kaj Blennow
Evaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the patient.
Neuro-degenerative diseases 2012;10(1-4):138-40.
2012: Alexander Navarrete Santos; Rolf-Edgar Silber; Andreas Simm; Kaj Blennow; Michael Ewers; Oskar Hansson; Lennart Minthon; David Prvulovic; Harald Hampel
Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;29(1):171-6.
2012: hugo vanderstichele; Dirk Wouters; Mirko Bibl; Sebastiaan Engelborghs; Nathalie Le Bastard; Piotr Lewczuk; Jose Luis Molinuevo; Lucilla Parnetti; Armand Perret-Liaudet; Leslie M Shaw; Charlotte Teunissen; Kaj Blennow
Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(1):65-73.
2012: Oskar Hansson; Kaj Blennow; Deborah R Gustafson; Erik Stomrud; Eugeen Vanmechelen; Henrik Zetterberg; Svante Ostling; Ingmar Skoog
Evaluation of plasma Aβ as predictor of Alzheimer's disease in older individuals without dementia: a population-based study.
Journal of Alzheimer's disease : JAD 2012;28(1):231-8.
2011: Ann Westman-Brinkmalm; Alexandra Abramsson; Kaj Blennow; Gunnar Brinkmalm; Chen Gang; Mikael K Gustavsson; Hermann Heumann; Josef Pannee; Malin von Otter; Henrik Zetterberg
SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration.
Journal of proteomics 2011;75(2):425-34.
2011: Bob Olsson; Henrik Zetterberg; Harald Hampel; Kaj Blennow
Biomarker-based dissection of neurodegenerative diseases.
Progress in neurobiology 2011;95(4):520-34.
2011: Taher Darreh-Shori; Anton Forsberg; Chelenk Kamil; Bengt Långström; Negar Modiri; Hiba Ahmed; Ove Almkvist; Niels Andreasen; Kaj Blennow; Agneta Nordberg
Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo.
Neurobiology of aging 2011;32(12):2320.e15-32.
2011: Lidia Glodzik; Yi Li; Pankaj Mehta; Lisa Mosconi; Elizabeth Pirraglia; Kenneth E Rich; Wai Hon Tsui; Hui Yu Wang; Henrik Zetterberg; Raymond Zinkowski; Kaj Blennow; Susan De Santi; Mony J de Leon
Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders.
Neurobiology of aging 2011;32(12):2131-41.
2011: Annika Ohrfelt; Rita Persson; Dzemila Secic; Eugeen Vanmechelen; Anders Wallin; Dag Aarsland; Kerstin Andersson; Clive G Ballard; Kaj Blennow; Gunnar Brinkmalm; Paul T Francis; Ezra Mulugeta; Henrik Zetterberg; Ann Westman-Brinkmalm
Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method.
Neurochemical research 2011;36(11):2029-42.
2011: D Heister; S Magda; L K McEvoy; Kaj Blennow; J B Brewer
Predicting MCI outcome with clinically available MRI and CSF biomarkers.
Neurology 2011;77(17):1619-28.
2011: Mariann Wall; Henrik Zetterberg; Niklas Mattsson; Kaj Blennow
[Automated cerebrospinal fluid cell count. A valuable contribution to diagnostics of brain diseases].
Läkartidningen 2011;108(40):1972-3.
2011: E Mörtberg; J Nordmark; Kaj Blennow; C Catry; H Decraemer; E Vanmechelen; H Zetterberg; Sten Rubertsson
Plasma tau protein in comatose patients after cardiac arrest treated with therapeutic hypothermia.
Acta anaesthesiologica Scandinavica 2011;55(9):1132-8.
2011: Rahul S Desikan; Dominic Holland; Bradley T Hyman; Linda K McEvoy; J Cooper Roddey; Wesley K Thompson; Paul S Aisen; Kaj Blennow; James B Brewer; Anders M Dale
Amyloid-β associated volume loss occurs only in the presence of phospho-tau.
Annals of neurology 2011;70(4):657-61.
2011: Camilla Hesse; Inger Johansson; Göran Larson; Niklas Mattsson; Henrik Zetterberg; Henrik Anckarsäter; Rolf Anckarsäter; Ulf Andreasson; Kaj Blennow; Daniel Bremell; Lars Hagberg; Adnan Halim; Ammi Grahn
The N-terminal domain of α-dystroglycan, released as a 38 kDa protein, is increased in cerebrospinal fluid in patients with Lyme neuroborreliosis.
Biochemical and biophysical research communications 2011;412(3):494-9.
2011: Angelica Dahlgren; Claudia Fahlke; Lars Oreland; Hanna-Linn Wargelius; Henrik Zetterberg; Ulf Berggren; Kristina J Berglund; Kaj Blennow; Jan Balldin
Do alcohol-dependent individuals with DRD2 A1 allele have an increased risk of relapse? A pilot study.
Alcohol and alcoholism (Oxford, Oxfordshire) 2011;46(5):509-13.
2011: Per Johansson; Fernand Labrie; Niklas Mattsson; Claes Ohlsson; Kaj Blennow; Oskar Hansson; Jan-Ove Johansson; Anders Wallin; Henrik Zetterberg; Johan Svensson
Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women.
Clinical endocrinology 2011;75(3):301-8.
2011: Sara Landgren; Jörgen A Engel; Petri Hyytiä; Henrik Zetterberg; Kaj Blennow; Elisabet Jerlhag
Expression of the gene encoding the ghrelin receptor in rats selected for differential alcohol preference.
Behavioural brain research 2011;221(1):182-8.
2011: Lucilla Parnetti; Vincenzo Talesa; A K Wallin; Henrik Zetterberg; D Chiasserini; C Hüls; L Minthon; M Ohlson; Niels Andreasen; U Andreasson; Kaj Blennow
Changes in CSF acetyl- and butyrylcholinesterase activity after long-term treatment with AChE inhibitors in Alzheimer's disease.
Acta neurologica Scandinavica 2011;124(2):122-9.
2011: Adnan Halim; Göran Larson; Kaj Blennow; Gunnar Brinkmalm; Erik Portelius; Ulla Rüetschi; Ann Westman-Brinkmalm; Henrik Zetterberg; Jonas Nilsson
Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):11848-53.
2011: Philine Schneider; Stefan J Teipel; Olga Uspenskaya; Henrik Zetterberg; Andreas Bergmann; Kaj Blennow; Katharina Buerger; Andrea Ernst; Oskar Hansson; Oliver Hartmann; Lennart Minthon; Hans-Juergen Moeller; Dan Rujescu; Harald Hampel
Antihypertensive therapy is associated with reduced rate of conversion to Alzheimer's disease in midregional proatrial natriuretic peptide stratified subjects with mild cognitive impairment.
Biological psychiatry 2011;70(2):145-51.
2011: Niklas Mattsson; John McAuliffe; Marc Mercken; Abhay Moghekar; José Luis Molinuevo; Thomas J Montine; William Nowatzke; Richard J O'Brien; Markus Otto; George P Paraskevas; Lucilla Parnetti; Staffan Persson; Ronald C. Petersen; David Prvulovic; Robert A Rissman; Elio Scarpini; Johannes Schröder; Leslie M Shaw; Anders Skinningsrud; Brith Skrogstad; Hilkka Soininen; Annette Spreer; Alessandro Stefani; Leda Talib; Charlotte Teunissen; John Q Trojanowski; Hayrettin Tumani; Robert M Umek; Bianca Van Broeck; hugo Marcel vanderstichele; Laszlo Vecsei; Marcel M Verbeek; Manfred Windisch; Henrik Zetterberg; Jing Zhang; Luisella Bocchio-Chiavetto; Maria C Carrillo; Sonia Chalbot; Davide Chiasserini; Els Coart; Neal Cutler; Gunilla Dahlfors; Herman P M de Reus; Stefan Duller; Anne M Fagan; Orestes Forlenza; Giovanni B Frisoni; Douglas Galasko; Daniela Galimberti; Harald Hampel; Aase Handberg; Michael T Heneka; Adrianna Z Herskovits; Sanna-Kaisa Herukka; David M Holtzman; Christian Humpel; Bradley T Hyman; Khalid Iqbal; Mathias Jucker; Stephan A Kaeser; Elmar Kaiser; Elisabeth Kapaki; Daniel Kidd; Peter Klivenyi; Cindy S Knudsen; Markus P Kummer; Piotr Lewczuk; Qiao-Xin Li; Albert Lladó; James Lui; Ralph Martins; Colin L Masters; Ulf Andreasson; Hiroyuki Arai; Sat Dev Batish; Sergio Bernardini; Marinus A Blankenstein; Kaj Blennow
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2011;7(4):386-395.e6.
2011: Taher Darreh-Shori; Chelenk Kamil; Negar Modiri; Hiba Ahmed; Niels Andreasen; Souad Baza; Kaj Blennow; agneta nordberg
The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase.
Neurobiology of aging 2011;32(7):1236-48.
2011: Niklas Mattsson; Shahrzad Tabatabaei; Per Johansson; Oskar Hansson; Ulf Andreasson; Jan-Eric Månsson; Jan-Ove Johansson; Bob Olsson; Anders Wallin; Johan Svensson; Kaj Blennow; Henrik Zetterberg
Cerebrospinal fluid microglial markers in Alzheimer's disease: elevated chitotriosidase activity but lack of diagnostic utility.
Neuromolecular medicine 2011;13(2):151-9.
2011: Alexandra Abramsson; Sara Landgren; Madeleine Zetterberg; Mona Seibt Palmer; Lennart Minthon; Deborah R Gustafson; Ingmar Skoog; Kaj Blennow; Henrik Zetterberg
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Neuromolecular medicine 2011;13(2):160-6.
2011: Nunzio Pomara; Davide Bruno; Jay J Nierenberg; John J Sidtis; Frank T Martiniuk; Pankaj D Mehta; Henrik Zetterberg; Kaj Blennow
TOMM40 poly-T variants and cerebrospinal fluid amyloid beta levels in the elderly.
Neurochemical research 2011;36(6):1124-8.
2011: Thiemo Rudolph; Annica Sjölander; Mona Seibt Palmér; Lennart Minthon; Anders Wallin; Niels Andreasen; Gunnar Tasa; Erkki Juronen; Kaj Blennow; Henrik Zetterberg; Madeleine Zetterberg
Ubiquitin carboxyl-terminal esterase L1 (UCHL1) S18Y polymorphism in patients with cataracts.
Ophthalmic genetics 2011;32(2):75-9.
2011: Erik Portelius; Eric Price; Gunnar Brinkmalm; Mark Stiteler; Maria Olsson; Rita Persson; Ann Westman-Brinkmalm; Henrik Zetterberg; Adam J Simon; Kaj Blennow
A novel pathway for amyloid precursor protein processing.
Neurobiology of aging 2011;32(6):1090-8.
2011: Leslie M Shaw; Eric Siemers; Adam J Simon; Holly Soares; John Q Trojanowski; hugo vanderstichele; Kaj Blennow; Els Coart; Robert A Dean; Michal Figurski; Malgorzata Knapik-Czajka; Virginia M-Y Lee; Piotr Lewczuk; William Potter
Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI.
Acta neuropathologica 2011;121(5):597-609.
2011: Katharina Buerger; Olga Uspenskaya; Oliver Hartmann; Oskar Hansson; Lennart Minthon; Kaj Blennow; Hans-Juergen Moeller; Stefan J Teipel; Andrea Ernst; Andreas Bergmann; Harald Hampel
Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment.
The Journal of clinical psychiatry 2011;72(4):556-63.
2011: Kaj Blennow; M Jonsson; Niels Andreasen; Lars Rosengren; Anders Wallin; P A Hellström; Henrik Zetterberg
No neurochemical evidence of brain injury after blast overpressure by repeated explosions or firing heavy weapons.
Acta neurologica Scandinavica 2011;123(4):245-51.
2011: Svante Ostling; Deborah Gustafson; Kaj Blennow; Anne Börjesson-Hanson; Margda Waern
Psychotic symptoms in a population-based sample of 85-year-old individuals with dementia.
Journal of geriatric psychiatry and neurology 2011;24(1):3-8.
2011: Kaj Blennow
Dementia in 2010: Paving the way for Alzheimer disease drug development.
Nature reviews. Neurology 2011;7(2):65-6.
2011: Ezra Mulugeta; Elisabet Londos; Clive G Ballard; Guido Alves; Henrik Zetterberg; Kaj Blennow; Ragnhild Skogseth; Lennart Minthon; Dag Aarsland
CSF amyloid β38 as a novel diagnostic marker for dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2011;82(2):160-4.
2011: N Mattsson; Henrik Zetterberg; S Bianconi; N M Yanjanin; R Fu; J-E Månsson; F D Porter; Kaj Blennow
Gamma-secretase-dependent amyloid-beta is increased in Niemann-Pick type C: a cross-sectional study.
Neurology 2011;76(4):366-72.
2011: Ronald Lautner; Niklas Mattsson; Bob Olsson; Michael Schöll; Kristin Augutis; Kaj Blennow; Henrik Zetterberg
Biomarkers for microglial activation in Alzheimer's disease.
International journal of Alzheimer's disease 2011;2011():939426.
2011: Hong Jiang; Rena Li; David Prvulovic; Kaj Blennow; Harald Hampel; Anders Wallin; Yong Shen
Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease.
Molecular neurodegeneration 2011;6():69.
2011: Ezra Mulugeta; Ragnhild Skogseth; Henrik Zetterberg; Clive Ballard; Kaj Blennow; Oskar Hansson; Elisabet Londos; Lennart Minthon; Dag Aarsland
Cerebrospinal Fluid Levels of sAPPα and sAPPβ in Lewy Body and Alzheimer's Disease: Clinical and Neurochemical Correlates.
International journal of Alzheimer's disease 2011;2011():495025.
2011: Maria Bjerke; Kaj Blennow; Ake Edman; Anders Wallin; Henrik Zetterberg; Ulf Andreasson
Cerebrospinal fluid matrix metalloproteinases and tissue inhibitor of metalloproteinases in combination with subcortical and cortical biomarkers in vascular dementia and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;27(3):665-76.
2011: Erik Portelius; Ulf Andreasson; Kaj Blennow; Niklas Mattsson; Henrik Zetterberg
Novel aβ isoforms in Alzheimer's disease - their role in diagnosis and treatment.
Current pharmaceutical design 2011;17(25):2594-602.
2011: Sara Landgren; Henrik Zetterberg; Claudia Fahlke; Elisabet Jerlhag; Jan Balldin; Ulf Berggren; Kristina Berglund; Kaj Blennow; Jörgen A Engel
Reward-related genes and personality traits in alcohol-dependent individuals: a pilot case control study.
Neuropsychobiology 2011;64(1):38-46.
2011: Sindre Rolstad; Henrik Zetterberg; Anne Ingeborg Berg; Maria Bjerke; Kaj Blennow; Boo Johansson; Anders Wallin
Amyloid-β₄₂ is associated with cognitive impairment in healthy elderly and subjective cognitive impairment.
Journal of Alzheimer's disease : JAD 2011;26(1):135-42.
2011: Sonia Chalbot; Tormod Fladby; Inge Grundke-Iqbal; Niels Andreasen; Kaj Blennow; Henrik Zetterberg; Khalid Iqbal
Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;25(3):505-15.
2011: Christoffer Rosén; Niklas Mattsson; Per M Johansson; Ulf Andreasson; Anders Wallin; Oskar Hansson; Jan-Ove Johansson; John Lamont; Johan Svensson; Kaj Blennow; Henrik Zetterberg
Discriminatory Analysis of Biochip-Derived Protein Patterns in CSF and Plasma in Neurodegenerative Diseases.
Frontiers in aging neuroscience 2011;3():1.
2011: Tamanna Mustafiz; agneta nordberg; Erik Portelius; Henrik Zetterberg; Kaj Blennow; Mikael K Gustavsson; Mikko Hölttä; Christina Unger Lithner
Characterization of the brain β-amyloid isoform pattern at different ages of Tg2576 mice.
Neuro-degenerative diseases 2011;8(5):352-63.
2011: Anna M Bennet; Kaj Blennow; Ulrika K Eriksson; Margaret Gatz; Mun-Gwan Hong; Nancy L Pedersen; Andrey Alexeyenko; Chandra A Reynolds; Jonathan A Prince
Genetic association of sequence variants near AGER/NOTCH4 and dementia.
Journal of Alzheimer's disease : JAD 2011;24(3):475-84.
2011: Per Johansson; Niklas Mattsson; Anders Wallin; Henrik Zetterberg; Ulf Andreasson; Kaj Blennow; Oskar Hansson; Jan-Ove Johansson; Johan Svensson
Cerebrospinal fluid biomarkers for Alzheimer’s disease: diagnostic performance in a homogeneous mono-center population.
Journal of Alzheimer's disease : JAD 2011;24(3):537-46.
2011: M Andersson; Henrik Zetterberg; Lennart Minthon; Kaj Blennow; Elisabet Londos
The cognitive profile and CSF biomarkers in dementia with Lewy bodies and Parkinson's disease dementia.
International journal of geriatric psychiatry 2011;26(1):100-5.
2011: Abhay Sagare; Rashid Deane; Henrik Zetterberg; Anders Wallin; Kaj Blennow; Berislav V Zlokovic
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24(1):25-34.
2011: Erik Mörtberg; Henrik Zetterberg; Johanna Nordmark; Kaj Blennow; Lars Rosengren; Sten Rubertsson
S-100B is superior to NSE, BDNF and GFAP in predicting outcome of resuscitation from cardiac arrest with hypothermia treatment.
Resuscitation 2011;82(1):26-31.
2010: Annika Thorsell; Maria Bjerke; Johan Gobom; Eva Brunhage; Eugeen Vanmechelen; Niels Andreasen; Oskar Hansson; Lennart Minthon; Henrik Zetterberg; Kaj Blennow
Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease.
Brain research 2010;1362():13-22.
2010: Lisa Mosconi; Lidia Glodzik; Rachel Mistur; Pauline McHugh; Kenneth E Rich; Elizabeth Javier; Schantel Williams; Elizabeth Pirraglia; Susan De Santi; Pankaj D Mehta; Raymond Zinkowski; Kaj Blennow; Domenico Pratico'; Mony J de Leon
Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's.
Biological psychiatry 2010;68(10):913-21.
2010: Kaj Blennow
Biomarkers in Alzheimer's disease drug development.
Nature medicine 2010;16(11):1218-22.
2010: Peder Buchhave; Henrik Zetterberg; Kaj Blennow; Lennart Minthon; Sabina Janciauskiene; Oskar Hansson
Soluble TNF receptors are associated with Aβ metabolism and conversion to dementia in subjects with mild cognitive impairment.
Neurobiology of aging 2010;31(11):1877-84.
2010: Sara Bromander; Rolf Anckarsäter; Bo Ahrén; Marianne Kristiansson; Kaj Blennow; Agneta Holmäng; Henrik Zetterberg; Henrik Anckarsäter; Caroline E Wass
Cerebrospinal fluid insulin during non-neurological surgery.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(10):1167-70.
2010: Guido Alves; Kolbjørn Brønnick; Dag Aarsland; Kaj Blennow; Henrik Zetterberg; Clive G Ballard; Martin Wilhelm Kurz; Ulf Andreasson; Ole-Bjørn Tysnes; Jan Petter Larsen; Ezra Mulugeta
CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study.
Journal of neurology, neurosurgery, and psychiatry 2010;81(10):1080-6.
2010: K Wesnes; Chris Edgar; Niels Andreasen; P Annas; H Basun; Lars Lannfelt; Henrik Zetterberg; Kaj Blennow; L Minthon
Computerized cognition assessment during acetylcholinesterase inhibitor treatment in Alzheimer's disease.
Acta neurologica Scandinavica 2010;122(4):270-7.
2010: Radu Constantinescu; Ulf Andreasson; Susann Li; Vladimir N Podust; Niklas Mattsson; Rolf Anckarsäter; Henrik Anckarsäter; Lars Rosengren; Björn Holmberg; Kaj Blennow; Carsten Wikkelsö; Ulla Rüetschi; Henrik Zetterberg
Proteomic profiling of cerebrospinal fluid in parkinsonian disorders.
Parkinsonism & related disorders 2010;16(8):545-9.
2010: Sara Landgren; Elisabet Jerlhag; Jarmila Hallman; Lars Oreland; Lauren Lissner; Elisabeth Strandhagen; Dag Steinar Thelle; Henrik Zetterberg; Kaj Blennow; Jörgen A Engel
Genetic variation of the ghrelin signaling system in females with severe alcohol dependence.
Alcoholism, clinical and experimental research 2010;34(9):1519-24.
2010: Anders M Fjell; Kristine B Walhovd; Christine Fennema-Notestine; Linda K McEvoy; Donald J Hagler; Dominic Holland; Kaj Blennow; James B Brewer; Anders M Dale
Brain atrophy in healthy aging is related to CSF levels of Aβ1-42.
Cerebral cortex (New York, N.Y. : 1991) 2010;20(9):2069-79.
2010: Malin von Otter; Sara Landgren; Staffan Nilsson; Caroline Lundvall; Lennart Minthon; Nenad Bogdanovic; Niels Andreasen; Deborah R Gustafson; Ingmar Skoog; Anders Wallin; Anna Zettergren; Hans Nissbrandt; Madeleine Zetterberg; Gunnar Tasa; Kaj Blennow; Henrik Zetterberg
Kinesin light chain 1 gene haplotypes in three conformational diseases.
Neuromolecular medicine 2010;12(3):229-36.
2010: Sara Landgren; Mona Seibt Palmér; Ingmar Skoog; Lennart Minthon; Anders Wallin; Niels Andreasen; Madeleine Zetterberg; Kaj Blennow; Henrik Zetterberg
No association of VEGF polymorphims with Alzheimer's disease.
Neuromolecular medicine 2010;12(3):224-8.
2010: Thomas Nilsson; Sara Bromander; Rolf Anckarsäter; Marianne Kristiansson; Anders Forsman; Kaj Blennow; Henrik Zetterberg; Henrik Anckarsäter; Caroline Wass
Neurochemical measures co-vary with personality traits: forensic psychiatric findings replicated in a general population sample.
Psychiatry research 2010;178(3):525-30.
2010: Geert De Meyer; Fred Shapiro; hugo vanderstichele; Eugeen Vanmechelen; Sebastiaan Engelborghs; Peter Paul De Deyn; Els Coart; Oskar Hansson; Lennart Minthon; Henrik Zetterberg; Kaj Blennow; Leslie Shaw; John Q Trojanowski
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people.
Archives of neurology 2010;67(8):949-56.
2010: Erik Portelius; Nenad Bogdanovic; Mikael K Gustavsson; Inga Volkmann; Gunnar Brinkmalm; Henrik Zetterberg; Bengt Winblad; Kaj Blennow
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease.
Acta neuropathologica 2010;120(2):185-93.
2010: Sonia Chalbot; Henrik Zetterberg; Kaj Blennow; Tormod Fladby; Inge Grundke-Iqbal; Khalid Iqbal
Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity: a biomarker of blood-cerebrospinal fluid barrier permeability.
Neuroscience letters 2010;478(3):179-83.
2010: Harald Hampel; Richard Frank; Karl Broich; Stefan J Teipel; Russell G Katz; John Hardy; Karl Herholz; Arun L W Bokde; Frank Jessen; Yvonne C Hoessler; Wendy R Sanhai; Henrik Zetterberg; Janet Woodcock; Kaj Blennow
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.
Nature reviews. Drug discovery 2010;9(7):560-74.
2010: Jonny Daborg; Malin von Otter; Annica Sjölander; Staffan Nilsson; Lennart Minthon; Deborah R Gustafson; Ingmar Skoog; Kaj Blennow; Henrik Zetterberg
Association of the RAGE G82S polymorphism with Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(7):861-7.
2010: Alexandra Abramsson; Ann Westman-Brinkmalm; Josef Pannee; Mikael Gustavsson; Malin von Otter; Kaj Blennow; Gunnar Brinkmalm; Petronella Kettunen; Henrik Zetterberg
Proteomics profiling of single organs from individual adult zebrafish.
Zebrafish 2010;7(2):161-8.
2010: Valgeir Thorvaldsson; Arto Nordlund; Ivar Reinvang; Kaj Blennow; Henrik Zetterberg; Anders Wallin; Boo Johansson
Memory in individuals with mild cognitive impairment in relation to APOE and CSF Abeta42.
International psychogeriatrics / IPA 2010;22(4):598-606.
2010: Harald Hampel; Yong Shen; Dominic M Walsh; Paul Aisen; Les M Shaw; Henrik Zetterberg; John Q Trojanowski; Kaj Blennow
Biological markers of amyloid beta-related mechanisms in Alzheimer's disease.
Experimental neurology 2010;223(2):334-46.
2010: Erik Portelius; Gunnar Brinkmalm; Aijun Tran; Ulf Andreasson; Henrik Zetterberg; Ann Westman-Brinkmalm; Kaj Blennow; Annika Ohrfelt
Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal fluid.
Experimental neurology 2010;223(2):351-8.
2010: D R Gustafson; L Melchior; E Eriksson; V Sundh; Kaj Blennow; I Skoog
The ACE Insertion Deletion polymorphism relates to dementia by metabolic phenotype, APOEepsilon4, and age of dementia onset.
Neurobiology of aging 2010;31(6):910-6.
2010: Chandra A Reynolds; Mun-Gwan Hong; Ulrika K Eriksson; Kaj Blennow; Fredrik Wiklund; Boo Johansson; Bo Malmberg; Stig Berg; Andrey Alexeyenko; Henrik Grönberg; Margaret Gatz; Nancy L Pedersen; Jonathan A Prince
Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.
Human molecular genetics 2010;19(10):2068-78.
2010: Anders Wallin; Kaj Blennow; Henrik Zetterberg; Elisabet Londos; Lennart Minthon; Oskar Hansson
CSF biomarkers predict a more malignant outcome in Alzheimer disease.
Neurology 2010;74(19):1531-7.
2010: John Q Trojanowski; Hugo Vandeerstichele; Magdalena Korecka; Christopher M Clark; Paul S Aisen; Ronald C. Petersen; Kaj Blennow; Holly Soares; Adam Simon; Piotr Lewczuk; Robert Dean; Eric Siemers; William Z Potter; Michael Weiner; Clifford R Jack; William J Jagust; Arthur W Toga; Virginia M-Y Lee; Leslie M Shaw
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(3):230-8.
2010: Niklas Mattsson; Kaj Blennow; Henrik Zetterberg
Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2010;48(5):603-7.
2010: Pia Gudmundsson; Ingmar Skoog; Margda Waern; Kaj Blennow; Henrik Zetterberg; Lars Rosengren; Deborah Gustafson
Is there a CSF biomarker profile related to depression in elderly women?
Psychiatry research 2010;176(2-3):174-8.
2010: Juha O Rinne; David J Brooks; Martin N Rossor; Nick C Fox; Roger Bullock; William E Klunk; Chester A Mathis; Kaj Blennow; Jerome Barakos; Aren A Okello; Sofia Rodriguez Martinez de Liano; Enchi Liu; Martin Koller; Keith M Gregg; Dale Schenk; Ronald Black; Michael Grundman
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study.
Lancet neurology 2010;9(4):363-72.
2010: Jan Balldin; Ulf Berggren; Kristina Berglund; Kaj Blennow; Claudia Fahlke; Henrik Zetterberg
Gamma-glutamyltransferase in alcohol use disorders: Modification of decision limits in relation to treatment goals?
Scandinavian journal of clinical and laboratory investigation 2010;70(2):71-4.
2010: Kajsa Sämgård; Henrik Zetterberg; Kaj Blennow; Oskar Hansson; Lennart Minthon; Elisabet Londos
Cerebrospinal fluid total tau as a marker of Alzheimer's disease intensity.
International journal of geriatric psychiatry 2010;25(4):403-10.
2010: Hans Brunnström; Nina Rawshani; Henrik Zetterberg; Kaj Blennow; Lennart Minthon; Ulla Passant; Elisabet Englund
Cerebrospinal fluid biomarker results in relation to neuropathological dementia diagnoses.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(2):104-9.
2010: Kaj Blennow; Harald Hampel; Michael Weiner; Henrik Zetterberg
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease.
Nature reviews. Neurology 2010;6(3):131-44.
2010: Niklas Mattsson; Karin Sävman; Gustaf Osterlundh; Kaj Blennow; Henrik Zetterberg
Converging molecular pathways in human neural development and degeneration.
Neuroscience research 2010;66(3):330-2.
2010: Michael Jonsson; Henrik Zetterberg; E van Straaten; Karin Lind; Steinar Syversen; Ake Edman; Kaj Blennow; Lars Rosengren; Leonardo Pantoni; D Inzitari; Anders Wallin
Cerebrospinal fluid biomarkers of white matter lesions - cross-sectional results from the LADIS study.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2010;17(3):377-82.
2010: E H Wiig; P Annas; H Basun; Niels Andreasen; Lars Lannfelt; Henrik Zetterberg; Kaj Blennow; L Minthon
The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer's disease.
Acta neurologica Scandinavica 2010;121(3):186-93.
2010: Oskar Hansson; Henrik Zetterberg; Eugeen Vanmechelen; hugo vanderstichele; Ulf Andreasson; Elisabet Londos; Anders Wallin; Lennart Minthon; Kaj Blennow
Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment.
Neurobiology of aging 2010;31(3):357-67.
2010: Henrik Zetterberg; Niklas Mattsson; Les M Shaw; Kaj Blennow
Biochemical markers in Alzheimer's disease clinical trials.
Biomarkers in medicine 2010;4(1):91-8.
2010: Erik Stomrud; Oskar Hansson; Henrik Zetterberg; Kaj Blennow; Lennart Minthon; Elisabet Londos
Correlation of longitudinal cerebrospinal fluid biomarkers with cognitive decline in healthy older adults.
Archives of neurology 2010;67(2):217-23.
2010: Malin von Otter; Sara Landgren; Staffan Nilsson; Madeleine Zetterberg; Dragana Celojevic; Petra Bergström; Lennart Minthon; Nenad Bogdanovic; Niels Andreasen; Deborah R Gustafson; Ingmar Skoog; Anders Wallin; Gunnar Tasa; Kaj Blennow; Michael Nilsson; Ola Hammarsten; Henrik Zetterberg
Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract.
Mechanisms of ageing and development 2010;131(2):105-10.
2010: Chandra A Reynolds; Mun-Gwan Hong; Ulrika K Eriksson; Kaj Blennow; Boo Johansson; Bo Malmberg; Stig Berg; Margaret Gatz; Nancy L Pedersen; Anna M Bennet; Jonathan A Prince
Sequence variation in SORL1 and dementia risk in Swedes.
Neurogenetics 2010;11(1):139-42.
2010: Erik Stomrud; Oskar Hansson; Lennart Minthon; Kaj Blennow; Ingmar Rosén; Elisabet Londos
Slowing of EEG correlates with CSF biomarkers and reduced cognitive speed in elderly with normal cognition over 4 years.
Neurobiology of aging 2010;31(2):215-23.
2010: Mia E Blomqvist; Shane McCarthy; Kaj Blennow; Björn Andersson; Jonathan A Prince
Evaluation of neprilysin sequence variation in relation to CSF β-Amyloid levels and Alzheimer disease risk.
International journal of molecular epidemiology and genetics 2010;1(1):47-52.
2010: Joakim Hertze; Lennart Minthon; Henrik Zetterberg; Eugeen Vanmechelen; Kaj Blennow; Oskar Hansson
Evaluation of CSF biomarkers as predictors of Alzheimer's disease: a clinical follow-up study of 4.7 years.
Journal of Alzheimer's disease : JAD 2010;21(4):1119-28.
2010: Henrik Zetterberg; Niklas Mattsson; Kaj Blennow
Cerebrospinal fluid analysis should be considered in patients with cognitive problems.
International journal of Alzheimer's disease 2010;2010():163065.
2010: Carol Man Gao; Alice Y Yam; Xuemei Wang; Erika Magdangal; Cleo Salisbury; David Peretz; Ronald N Zuckermann; Michael D Connolly; Oskar Hansson; Lennart Minthon; Henrik Zetterberg; Kaj Blennow; Joseph P Fedynyshyn; Sophie Allauzen
Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease.
PloS one 2010;5(12):e15725.
2010: Niels Andreasen; Kaj Blennow; Henrik Zetterberg
Neuroinflammation Screening in Immunotherapy Trials against Alzheimer's Disease.
International journal of Alzheimer's disease 2010;2010():638379.
2010: Henrik Zetterberg; Niklas Mattsson; Kaj Blennow; Bob Olsson
Use of theragnostic markers to select drugs for phase II/III trials for Alzheimer disease.
Alzheimer's research & therapy 2010;2(6):32.
2010: Lucilla Parnetti; Jens Wiltfang; Kaj Blennow
Should CSF Biomarkers Support a Routine Analysis for Early Diagnosis of Alzheimer's Disease?
International journal of Alzheimer's disease 2010;2010():293587.
2010: Johan Sundelöf; Johan Sundström; Oskar Hansson; Maria Eriksdotter-Jönhagen; Vilmantas Giedraitis; Anders Larsson; Malin Degerman-Gunnarsson; Martin Ingelsson; Lennart Minthon; Kaj Blennow; Lena Kilander; Hans Basun; Lars Lannfelt
Higher cathepsin B levels in plasma in Alzheimer's disease compared to healthy controls.
Journal of Alzheimer's disease : JAD 2010;22(4):1223-30.
2010: Davide Chiasserini; Lucilla Parnetti; Ulf Andreasson; Henrik Zetterberg; David Giannandrea; Paolo Calabresi; Kaj Blennow
CSF levels of heart fatty acid binding protein are altered during early phases of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(4):1281-8.
2010: Philipp Spitzer; Hans-Wolfgang Klafki; Kaj Blennow; Luc BUEE; Hermann Esselmann; Sanna-Kaisa Herruka; Connie Jimenez; Peter Klivenyi; Piotr Lewczuk; Juan Manuel Maler; Katrin Markus; Helmut E Meyer; Chris Morris; Thorsten Müller; Markus Otto; Lucilla Parnetti; Hilkka Soininen; Susanna Schraen; Charlotte Teunissen; Laszlo Vecsei; Henrik Zetterberg; Jens Wiltfang
cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases.
International journal of Alzheimer's disease 2010;2010():.
2010: Annica Sjölander; Henrik Zetterberg; Ulf Andreasson; Lennart Minthon; Kaj Blennow
BACE1 gene variants do not influence BACE1 activity, levels of APP or Aβ isoforms in CSF in Alzheimer's disease.
Molecular neurodegeneration 2010;5():37.
2010: Anna M Bennet; Chandra A Reynolds; Margaret Gatz; Kaj Blennow; Nancy L Pedersen; Jonathan A Prince
Pleiotropy in the presence of allelic heterogeneity: alternative genetic models for the influence of APOE on serum LDL, CSF amyloid-β42, and dementia.
Journal of Alzheimer's disease : JAD 2010;22(1):129-34.
2010: Maria Bjerke; Erik Portelius; Lennart Minthon; Anders Wallin; Henrik Anckarsäter; Rolf Anckarsäter; Niels Andreasen; Henrik Zetterberg; Ulf Andreasson; Kaj Blennow
Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid.
International journal of Alzheimer's disease 2010;2010():.
2010: Niklas Mattsson; Henrik Zetterberg; Kaj Blennow
Lessons from Multicenter Studies on CSF Biomarkers for Alzheimer's Disease.
International journal of Alzheimer's disease 2010;2010():.
2010: Per Selnes; Kaj Blennow; Henrik Zetterberg; Ramune Grambaite; Lars Rosengren; Lisbeth Johnsen; Vidar Stenset; Tormod Fladby
Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid.
Cerebrospinal fluid research 2010;7():10.
2010: Erik Portelius; Bianca Van Broeck; Ulf Andreasson; Mikael K Gustavsson; Marc Mercken; Henrik Zetterberg; Herman Borghys; Kaj Blennow
Acute effect on the Aβ isoform pattern in CSF in response to γ-secretase modulator and inhibitor treatment in dogs.
Journal of Alzheimer's disease : JAD 2010;21(3):1005-12.
2010: Niklas Mattsson; Daniel Bremell; Rolf Anckarsäter; Kaj Blennow; Henrik Anckarsäter; Henrik Zetterberg; Lars Hagberg
Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism.
BMC neurology 2010;10():51.
2010: Johan Sundelöf; Johan Sundström; Oskar Hansson; Maria Eriksdotter-Jönhagen; Vilmantas Giedraitis; Anders Larsson; Malin Degerman-Gunnarsson; Martin Ingelsson; Lennart Minthon; Kaj Blennow; Lena Kilander; Hans Basun; Lars Lannfelt
Cystatin C levels are positively correlated with both Abeta42 and tau levels in cerebrospinal fluid in persons with Alzheimer's disease, mild cognitive impairment, and healthy controls.
Journal of Alzheimer's disease : JAD 2010;21(2):471-8.
2010: Henrik Zetterberg; Kristian Tullhög; Oskar Hansson; Lennart Minthon; Elisabet Londos; Kaj Blennow
Low incidence of post-lumbar puncture headache in 1,089 consecutive memory clinic patients.
European neurology 2010;63(6):326-30.
2010: Kaj Blennow; Henrik Zetterberg
Is it time for biomarker-based diagnostic criteria for prodromal Alzheimer's disease?
Alzheimer's research & therapy 2010;2(2):8.
2010: Sindre Rolstad; Arto Nordlund; Carl Eckerström; Marie H Gustavsson; Kaj Blennow; Pernille J Olesen; Henrik Zetterberg; Anders Wallin
High education may offer protection against tauopathy in patients with mild cognitive impairment.
Journal of Alzheimer's disease : JAD 2010;21(1):221-8.
2010: Niklas Mattsson; Per Johansson; Oskar Hansson; Anders Wallin; Jan-Ove Johansson; Ulf Andreasson; Oluf Andersen; Sara Haghighi; Maria Olsson; Mats Stridsberg; Johan Svensson; Kaj Blennow; Henrik Zetterberg
Converging pathways of chromogranin and amyloid metabolism in the brain.
Journal of Alzheimer's disease : JAD 2010;20(4):1039-49.
2010: C Eckerström; U Andreasson; E Olsson; S Rolstad; Kaj Blennow; Henrik Zetterberg; H Malmgren; A Edman; Anders Wallin
Combination of hippocampal volume and cerebrospinal fluid biomarkers improves predictive value in mild cognitive impairment.
Dementia and geriatric cognitive disorders 2010;29(4):294-300.
2010: Erik Portelius; Robert A Dean; Mikael K Gustavsson; Ulf Andreasson; Henrik Zetterberg; Eric Siemers; Kaj Blennow
A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer disease.
Alzheimer's research & therapy 2010;2(2):7.
2010: M Degerman Gunnarsson; Maria Lindau; A Wall; Kaj Blennow; Taher Darreh-Shori; Samar Basu; agneta nordberg; Anders Larsson; Lars Lannfelt; Hans Basun; Lena Kilander
Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study.
Dementia and geriatric cognitive disorders 2010;29(3):204-12.
2010: Madeleine Zetterberg; Annica Sjölander; Malin von Otter; Mona Seibt Palmér; Sara Landgren; Lennart Minthon; Anders Wallin; Niels Andreasen; Kaj Blennow; Henrik Zetterberg
Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease.
Molecular neurodegeneration 2010;5():11.
2010: Malin von Otter; Sara Landgren; Staffan Nilsson; Dragana Celojevic; Petra Bergström; Anna Zettergren; Hans Nissbrandt; Marek Drozdzik; Monika Bialecka; Mateusz Kurzawski; Kaj Blennow; Michael Nilsson; Ola Hammarsten; Henrik Zetterberg
Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.
BMC medical genetics 2010;11():36.
2010: Noel G Faux; Craig W Ritchie; Adam Gunn; Alan Rembach; Andrew Tsatsanis; Justin Bedo; John Edward Harrison; Lars Lannfelt; Kaj Blennow; Henrik Zetterberg; Martin Ingelsson; Colin L Masters; Rudolph E Tanzi; Jeffrey L Cummings; Caroline M Herd; Ashley I Bush
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses.
Journal of Alzheimer's disease : JAD 2010;20(2):509-16.
2010: Erik Portelius; Ulf Andreasson; John M Ringman; Katharina Buerger; Jonny Daborg; Peder Buchhave; Oskar Hansson; Andreas Harmsen; Mikael K Gustavsson; Eric Hanse; Douglas Galasko; Harald Hampel; Kaj Blennow; Henrik Zetterberg
Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease.
Molecular neurodegeneration 2010;5():2.
2010: Christina Gustavson; Caroline Wass; Jan-Eric Mansson; Kaj Blennow; Anders Forsman; Henrik Anckarsater; Thomas Nilsson
Platelet monoamine oxidase B activity did not predict destructive personality traits or violent recidivism: a prospective study in male forensic psychiatric examinees.
Neuropsychobiology 2010;61(2):87-96.
2010: Harald Hampel; Kaj Blennow; Leslie M Shaw; Yvonne C Hoessler; Henrik Zetterberg; John Q Trojanowski
Total and phosphorylated tau protein as biological markers of Alzheimer's disease.
Experimental gerontology 2010;45(1):30-40.
2010: Henrik Zetterberg; Kaj Blennow; Eric Hanse
Amyloid beta and APP as biomarkers for Alzheimer's disease.
Experimental gerontology 2010;45(1):23-9.
2010: Ulf Berggren; Claudia Fahlke; Kristina J Berglund; Kathleen Wadell; Henrik Zetterberg; Kaj Blennow; Dag Thelle; Jan Balldin
Dopamine D2 receptor genotype is associated with increased mortality at a 10-year follow-up of alcohol-dependent individuals.
Alcohol and alcoholism (Oxford, Oxfordshire) 2010;45(1):1-5.
2009: Stephen Salloway; R Sperling; Sid Gilman; Nick C Fox; Kaj Blennow; M Raskind; Marwan Sabbagh; Lawrence Honig; Rachelle S Doody; C H van Dyck; R Mulnard; J Barakos; K M Gregg; E Liu; I Lieberburg; Dale Schenk; R Black; M Grundman
A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease.
Neurology 2009;73(24):2061-70.
2009: Désirée Gavhed; Selma Olsson Akefeldt; Gustaf Osterlundh; Evaldas Laurencikas; Lars Hjorth; Kaj Blennow; Lars Rosengren; Jan-Inge Henter
Biomarkers in the cerebrospinal fluid and neurodegeneration in Langerhans cell histiocytosis.
Pediatric blood & cancer 2009;53(7):1264-70.
2009: Sara Landgren; Jörgen A Engel; Malin E Andersson; Arturo Gonzalez-Quintela; Joaquin Campos; Staffan Nilsson; Henrik Zetterberg; Kaj Blennow; Elisabet Jerlhag
Association of nAChR gene haplotypes with heavy alcohol use and body mass.
Brain research 2009;1305 Suppl():S72-9.
2009: Sonia Chalbot; Henrik Zetterberg; Kaj Blennow; Tormod Fladby; Inge Grundke-Iqbal; Khalid Iqbal
Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease.
Clinical chemistry 2009;55(12):2171-9.
2009: Eleonore Rydén; Christian Johansson; Kaj Blennow; Mikael Landén
Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(12):1667-74.
2009: Annica Sjölander; Malin E Andersson; Henrik Zetterberg; Lennart Minthon; Nenad Bogdanovic; Kaj Blennow
Alzheimer's disease: No effect of the CDK5 gene on CSF biomarkers, neuropathology or disease risk.
Molecular medicine reports 2009;2(6):989-92.
2009: Niklas Mattsson; Kaj Blennow; Henrik Zetterberg
CSF biomarkers: pinpointing Alzheimer pathogenesis.
Annals of the New York Academy of Sciences 2009;1180():28-35.
2009: Chandra A Reynolds; Mun-Gwan Hong; Ulrika K Eriksson; Kaj Blennow; Anna M Bennet; Boo Johansson; Bo Malmberg; Stig Berg; Fredrik Wiklund; Margaret Gatz; Nancy L Pedersen; Jonathan A Prince
A survey of ABCA1 sequence variation confirms association with dementia.
Human mutation 2009;30(9):1348-54.
2009: Katharina Buerger; Giovanni B Frisoni; Olga Uspenskaya; Michael Ewers; Henrik Zetterberg; Cristina Geroldi; Giuliano Binetti; Peter Johannsen; Paolo Maria Rossini; Lars-Olof Wahlund; Bruno Vellas; Kaj Blennow; Harald Hampel
Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI).
Experimental gerontology 2009;44(9):579-85.
2009: Ola Philipson; Per Hammarström; K Peter R Nilsson; Erik Portelius; Tommie Olofsson; Martin Ingelsson; Bradley T Hyman; Kaj Blennow; Lars Lannfelt; Hannu Kalimo; Lars N G Nilsson
A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
Neurobiology of aging 2009;30(9):1393-405.
2009: Henrik Zetterberg; Fatih Tanriverdi; Kursad Unluhizarci; Ahmet Selcuklu; Fahrettin Kelestimur; Kaj Blennow
Sustained release of neuron-specific enolase to serum in amateur boxers.
Brain injury : [BI] 2009;23(9):723-6.
2009: Niklas Mattsson; Henrik Zetterberg; Oskar Hansson; Niels Andreasen; Lucilla Parnetti; Michael Jonsson; Sanna-Kaisa Herukka; Wiesje M van der Flier; Marinus A Blankenstein; Michael Ewers; Kenneth Rich; Elmar Kaiser; Marcel Verbeek; Magda Tsolaki; Ezra Mulugeta; Erik Rosén; Dag Aarsland; Pieter Jelle Visser; Johannes Schröder; Jan Marcusson; Mony de Leon; Harald Hampel; Philip scheltens; Tuula Pirttilä; Anders Wallin; Maria Eriksdotter Jönhagen; Lennart Minthon; Bengt Winblad; Kaj Blennow
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.
JAMA : the journal of the American Medical Association 2009;302(4):385-93.
2009: Jakub Kwieciński; Marcin Kłak; Estelle Trysberg; Kaj Blennow; Andrej Tarkowski; Tao Jin
Relationship between elevated cerebrospinal fluid levels of plasminogen activator inhibitor 1 and neuronal destruction in patients with neuropsychiatric systemic lupus erythematosus.
Arthritis and rheumatism 2009;60(7):2094-101.
2009: Pieter Jelle Visser; Frans Verhey; Dirk L Knol; Philip scheltens; Lars-Olof Wahlund; Yvonne Freund-Levi; Magdalini Tsolaki; Lennart Minthon; Asa K Wallin; Harald Hampel; Katharina Bürger; Tuula Pirttila; Hilkka Soininen; Marcel Olde Rikkert; Marcel M Verbeek; Luiza Spiru; Kaj Blennow
Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study.
Lancet neurology 2009;8(7):619-27.
2009: Y Zhang; Elisabet Londos; Lennart Minthon; C Wattmo; Kaj Blennow; H J Liu; Lena Bronge; Peter Aspelin; Lars-Olof Wahlund
Medial temporal lobe atrophy increases the specificity of cerebrospinal fluid biomarkers in Alzheimer disease with minor cerebrovascular changes.
Acta radiologica (Stockholm, Sweden : 1987) 2009;50(6):674-81.
2009: Ulf Berggren; Claudia Fahlke; Kristina J Berglund; Kaj Blennow; Henrik Zetterberg; Jan Balldin
Thrombocytopenia in early alcohol withdrawal is associated with development of delirium tremens or seizures.
Alcohol and alcoholism (Oxford, Oxfordshire) 2009;44(4):382-6.
2009: Dorothea Strozyk; Lenore J Launer; Paul A Adlard; Robert A Cherny; Andrew Tsatsanis; Irene Volitakis; Kaj Blennow; Helen Petrovitch; Lon R White; Ashley I Bush
Zinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluid.
Neurobiology of aging 2009;30(7):1069-77.
2009: Niklas Marklund; Kaj Blennow; Henrik Zetterberg; Elisabeth Ronne-Engström; Per Enblad; Lars Hillered
Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury.
Journal of neurosurgery 2009;110(6):1227-37.
2009: Anders Wallin; Oskar Hansson; Kaj Blennow; Elisabet Londos; Lennart Minthon
Can CSF biomarkers or pre-treatment progression rate predict response to cholinesterase inhibitor treatment in Alzheimer's disease?
International journal of geriatric psychiatry 2009;24(6):638-47.
2009: Henrik Zetterberg; Niels Andreasen; Kaj Blennow
[Biomarkers in cerebrospinal fluid and blood in memory complaints].
Läkartidningen 2009;106(20):1386-9.
2009: Nicolaas Verwey; W M van der Flier; Kaj Blennow; C Clark; S Sokolow; P P De Deyn; Douglas Galasko; Harald Hampel; Tobias Hartmann; E Kapaki; Lars Lannfelt; P D Mehta; L Parnetti; Axel Petzold; T Pirttila; L Saleh; A Skinningsrud; J C V Swieten; M M Verbeek; J Wiltfang; Steven G Younkin; Philip scheltens; Marinus A Blankenstein
A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease.
Annals of clinical biochemistry 2009;46(Pt 3):235-40.
2009: Henrik Zetterberg; Ulf Andreasson; Kaj Blennow
CSF antithrombin III and disruption of the blood-brain barrier.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(13):2302-3; author reply 2303-4.
2009: Lidia Glodzik-Sobanska; Elizabeth Pirraglia; Miroslaw Brys; Susan De Santi; Lisa Mosconi; Kenneth E Rich; Remigiusz Switalski; LA Saint Louis; Martin Sadowski; Frank Martiniuk; Pankaj Mehta; Domenico Pratico'; Raymond Zinkowski; Kaj Blennow; Mony J de Leon
The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.
Neurobiology of aging 2009;30(5):672-81.
2009: Miroslaw Brys; Elizabeth Pirraglia; Kenneth Rich; Sindre Rolstad; Lisa Mosconi; Remigiusz Switalski; Lidia Glodzik-Sobanska; Susan De Santi; Raymond Zinkowski; Pankaj Mehta; Domenico Pratico'; LA Saint Louis; Anders Wallin; Kaj Blennow; Mony J de Leon
Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment.
Neurobiology of aging 2009;30(5):682-90.
2009: Kaj Blennow; Henrik Zetterberg
Use of CSF biomarkers in Alzheimer's disease clinical trials.
The journal of nutrition, health & aging 2009;13(4):358-61.
2009: Leslie M Shaw; hugo vanderstichele; Malgorzata Knapik-Czajka; Christopher M Clark; Paul S Aisen; Ronald C. Petersen; Kaj Blennow; Holly Soares; Adam Simon; Piotr Lewczuk; Robert Dean; Eric Siemers; William Potter; Virginia M-Y Lee; John Q Trojanowski
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.
Annals of neurology 2009;65(4):403-13.
2009: Niklas Mattsson; M Axelsson; S Haghighi; C Malmeström; G Wu; R Anckarsäter; S Sankaranarayanan; U Andreasson; Sten Fredrikson; A Gundersen; L Johnsen; T Fladby; A Tarkowski; E Trysberg; Anders Wallin; H Anckarsäter; J Lycke; Oluf Andersen; A J Simon; Kaj Blennow; Henrik Zetterberg
Reduced cerebrospinal fluid BACE1 activity in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2009;15(4):448-54.
2009: N Mattsson; M Yaong; Lars Rosengren; Kaj Blennow; J-E Månsson; Oluf Andersen; Henrik Zetterberg; S Haghighi; I Zho; Domenico Pratico'
Elevated cerebrospinal fluid levels of prostaglandin E2 and 15-(S)-hydroxyeicosatetraenoic acid in multiple sclerosis.
Journal of internal medicine 2009;265(4):459-64.
2009: Annica Sjölander; Lennart Minthon; Nenad Bogdanovic; Anders Wallin; Henrik Zetterberg; Kaj Blennow
The PPAR-alpha gene in Alzheimer's disease: lack of replication of earlier association.
Neurobiology of aging 2009;30(4):666-8.
2009: Kaj Blennow; Geert De Meyer; Oskar Hansson; L Minthon; Anders Wallin; Henrik Zetterberg; P Lewczuk; hugo vanderstichele; E Vanmechelen; J Kornhuber; J Wiltfang; I Heuser; W Maier; C Luckhaus; E Rüther; M Hüll; H Jahn; H J Gertz; Lutz Froelich; Harald Hampel; R Pernetzki
Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment.
The journal of nutrition, health & aging 2009;13(3):205-8.
2009: Annika Ohrfelt; Pierre Grognet; Niels Andreasen; Anders Wallin; Eugeen Vanmechelen; Kaj Blennow; Henrik Zetterberg
Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?
Neuroscience letters 2009;450(3):332-5.
2009: Oskar Hansson; Peder Buchhave; Henrik Zetterberg; Kaj Blennow; Lennart Minthon; S Warkentin
Combined rCBF and CSF biomarkers predict progression from mild cognitive impairment to Alzheimer's disease.
Neurobiology of aging 2009;30(2):165-73.
2009: Peder Buchhave; Sabina Janciauskiene; Henrik Zetterberg; Kaj Blennow; Lennart Minthon; Oskar Hansson
Elevated plasma levels of soluble CD40 in incipient Alzheimer's disease.
Neuroscience letters 2009;450(1):56-9.
2009: Magnus Gisslen; Jan Krut; Ulf Andreasson; Kaj Blennow; Paola Cinque; Bruce J Brew; Serena Spudich; Lars Hagberg; Lars Rosengren; Richard W Price; Henrik Zetterberg
Amyloid and tau cerebrospinal fluid biomarkers in HIV infection.
BMC neurology 2009;9():63.
2009: Erik Portelius; Bin Zhang; Mikael K Gustavsson; Gunnar Brinkmalm; Ann Westman-Brinkmalm; Henrik Zetterberg; Virginia M-Y Lee; John Q Trojanowski; Kaj Blennow
Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease.
Neuro-degenerative diseases 2009;6(5-6):258-62.
2009: Maria Bjerke; Ulf Andreasson; Sindre Rolstad; Arto Nordlund; Karin Lind; Henrik Zetterberg; Ake Edman; Kaj Blennow; Anders Wallin
Subcortical vascular dementia biomarker pattern in mild cognitive impairment.
Dementia and geriatric cognitive disorders 2009;28(4):348-56.
2009: Fredrik Boström; Oskar Hansson; Kaj Blennow; Lars Gerhardsson; Thomas Lundh; Lennart Minthon; Henrik Zetterberg; Elisabet Londos
Cerebrospinal fluid total tau is associated with shorter survival in dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2009;28(4):314-9.
2009: Lars Gerhardsson; Kaj Blennow; Thomas Lundh; Elisabet Londos; Lennart Minthon
Concentrations of metals, beta-amyloid and tau-markers in cerebrospinal fluid in patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 2009;28(1):88-94.
2009: Kaj Blennow; Henrik Zetterberg
Cerebrospinal fluid biomarkers for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;18(2):413-7.
2009: Lidia Glodzik; Susan De Santi; Kenneth E Rich; Miroslaw Brys; Elizabeth Pirraglia; Rachel Mistur; Remigiusz Switalski; Lisa Mosconi; Martin Sadowski; Henrik Zetterberg; Kaj Blennow; Mony J de Leon
Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology.
Journal of Alzheimer's disease : JAD 2009;18(3):509-13.
2009: Peder Buchhave; Kaj Blennow; Henrik Zetterberg; Erik Stomrud; Elisabet Londos; Niels Andreasen; Lennart Minthon; Oskar Hansson
Longitudinal study of CSF biomarkers in patients with Alzheimer's disease.
PloS one 2009;4(7):e6294.
2009: Elin S Blom; Vilmantas Giedraitis; Henrik Zetterberg; Hiroaki Fukumoto; Kaj Blennow; Bradley T Hyman; Michael C Irizarry; Lars-Olof Wahlund; Lars Lannfelt; Martin Ingelsson
Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype.
Dementia and geriatric cognitive disorders 2009;27(5):458-64.
2009: Ann Westman-Brinkmalm; Ulla Ruetschi; Erik Portelius; Ulf Andreasson; Gunnar Brinkmalm; Gosta Karlsson; Sara Hansson; Henrik Zetterberg; Kaj Blennow
Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases.
Frontiers in bioscience : a journal and virtual library 2009;14():1793-806.
2009: Erik Portelius; Gunnar Brinkmalm; Ai Jun Tran; Henrik Zetterberg; Ann Westman-Brinkmalm; Kaj Blennow
Identification of novel APP/Abeta isoforms in human cerebrospinal fluid.
Neuro-degenerative diseases 2009;6(3):87-94.
2009: Sara F Hansson; Ulf Andréasson; Mariann Wall; Ingmar Skoog; Niels Andreasen; Anders Wallin; Henrik Zetterberg; Kaj Blennow
Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients.
Journal of Alzheimer's disease : JAD 2009;16(2):389-97.
2009: Miroslaw Brys; Lidia Glodzik; Lisa Mosconi; Remigiusz Switalski; Susan De Santi; Elizabeth Pirraglia; Kenneth Rich; Byeong C Kim; Pankaj Mehta; Raymond Zinkowski; Domenico Pratico'; Anders Wallin; Henrik Zetterberg; Wai Hon Tsui; Henry Rusinek; Kaj Blennow; Mony J de Leon
Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(2):351-62.
2009: Pontus Wasling; Jonny Daborg; Ilse Riebe; My Andersson; Erik Portelius; Kaj Blennow; Eric Hanse; Henrik Zetterberg
Synaptic retrogenesis and amyloid-beta in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(1):1-14.
2009: Marie Kalm; Aya Fukuda; Hirotsugu Fukuda; Annika Ohrfelt; Birgitta Lannering; Thomas Björk-Eriksson; Kaj Blennow; Ildikó Márky; Klas Blomgren
Transient inflammation in neurogenic regions after irradiation of the developing brain.
Radiation research 2009;171(1):66-76.
2009: Henrik Zetterberg; David M Alexander; Demetrios A Spandidos; Kaj Blennow
Additional evidence for antagonistic pleiotropic effects of APOE.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009;5(1):75.
2008: Sara Landgren; Elisabet Jerlhag; Henrik Zetterberg; Arturo Gonzalez-Quintela; Joaquin Campos; Ulrica Olofsson; Staffan Nilsson; Kaj Blennow; Jörgen A Engel
Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.
Alcoholism, clinical and experimental research 2008;32(12):2054-61.
2008: Martin Ost; Karin Nylén; Ludwig Z Csajbok; Kaj Blennow; Lars Rosengren; Bengt Nellgård
Apolipoprotein E polymorphism and gender difference in outcome after severe traumatic brain injury.
Acta anaesthesiologica Scandinavica 2008;52(10):1364-9.
2008: Henrik Zetterberg; Johan Jacobsson; Lars Rosengren; Kaj Blennow; Peter M Andersen
Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis.
Journal of the neurological sciences 2008;273(1-2):67-9.
2008: Jin-Moo Lee; Kaj Blennow; Niels Andreasen; Omar Laterza; Vijay Modur; Jitka Olander; Feng Gao; Matt Ohlendorf; Jack H Ladenson
The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients.
Clinical chemistry 2008;54(10):1617-23.
2008: Christin Andersson; Kaj Blennow; Ove Almkvist; Niels Andreasen; Peter Engfeldt; Sven-Erik Johansson; Maria Lindau; Maria Eriksdotter-Jönhagen
Increasing CSF phospho-tau levels during cognitive decline and progression to dementia.
Neurobiology of aging 2008;29(10):1466-73.
2008: Madeleine Zetterberg; Sara Landgren; Malin E Andersson; Mona Seibt Palmér; Deborah R Gustafson; Ingmar Skoog; Lennart Minthon; Dag Steinar Thelle; Anders Wallin; Nenad Bogdanovic; Niels Andreasen; Kaj Blennow; Henrik Zetterberg
Association of complement factor H Y402H gene polymorphism with Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):720-6.
2008: Niklas Mattsson; Ulla Rüetschi; Yolande A L Pijnenburg; Marinus A Blankenstein; Vladimir N Podust; Susann Li; Inger Fagerberg; Lars Rosengren; Kaj Blennow; Henrik Zetterberg
Novel cerebrospinal fluid biomarkers of axonal degeneration in frontotemporal dementia.
Molecular medicine reports 2008;1(5):757-61.
2008: Lars Lannfelt; Kaj Blennow; Henrik Zetterberg; Stellan Batsman; David Ames; John Edward Harrison; Colin L Masters; Steve Targum; Ashley I Bush; Ross Murdoch; Janet Wilson; Craig W Ritchie
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial.
Lancet neurology 2008;7(9):779-86.
2008: Stefan Winblad; J E Månsson; Kaj Blennow; C Jensen; Lena Samuelsson; Christopher Lindberg
Cerebrospinal fluid tau and amyloid beta42 protein in patients with myotonic dystrophy type 1.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(9):947-52.
2008: Henrik Zetterberg; Ulf Andreasson; Oskar Hansson; Guoxin Wu; Sethu Sankaranarayanan; Malin E Andersson; Peder Buchhave; Elisabet Londos; Robert M Umek; Lennart Minthon; Adam J Simon; Kaj Blennow
Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease.
Archives of neurology 2008;65(8):1102-7.
2008: Mun-Gwan Hong; Chandra Reynolds; Margaret Gatz; Boo Johansson; Jennifer C Palmer; Harvest F Gu; Kaj Blennow; Pat Kehoe; Ulf de Faire; Nancy L Pedersen; Jonathan A Prince
Evidence that the gene encoding insulin degrading enzyme influences human lifespan.
Human molecular genetics 2008;17(15):2370-8.
2008: Giovanni B Frisoni; Wouter J P Henneman; Michael Weiner; Philip scheltens; Bruno Vellas; Emma Reynish; Jaroslava Hudecova; Harald Hampel; Katharina Burger; Kaj Blennow; Gunhild Waldemar; Peter Johannsen; Lars-Olof Wahlund; Giancarlo Zito; Paolo M Rossini; Bengt Winblad; Frederik Barkhof
The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(4):255-64.
2008: Arto Nordlund; Sindre Rolstad; Ola Klang; Karin Lind; Mona Pedersen; Kaj Blennow; Ake Edman; Stefan Hansen; Anders Wallin
Episodic memory and speed/attention deficits are associated with Alzheimer-typical CSF abnormalities in MCI.
Journal of the International Neuropsychological Society : JINS 2008;14(4):582-90.
2008: Henrik Zetterberg; U Rüetschi; E Portelius; G Brinkmalm; U Andreasson; Kaj Blennow; A Brinkmalm
Clinical proteomics in neurodegenerative disorders.
Acta neurologica Scandinavica 2008;118(1):1-11.
2008: A H Simonsen; James McGuire; Vladimir N Podust; H Davies; Lennart Minthon; Ingmar Skoog; Niels Andreasen; Anders Wallin; Gunhild Waldemar; Kaj Blennow
Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease.
Neurobiology of aging 2008;29(7):961-8.
2008: Elizabeth H Corder; Kaj Blennow; Jonathan A Prince
Genetic susceptibility sets for Alzheimer's disease identified from diverse candidate loci.
Rejuvenation research 2008;11(3):667-79.
2008: Erik Portelius; Sara F Hansson; Ai Jun Tran; Henrik Zetterberg; Pierre Grognet; Eugeen Vanmechelen; Kina Höglund; Gunnar Brinkmalm; Ann Westman-Brinkmalm; Eckhard Nordhoff; Kaj Blennow; Johan Gobom
Characterization of tau in cerebrospinal fluid using mass spectrometry.
Journal of proteome research 2008;7(5):2114-20.
2008: Michael Ewers; Zhenyu Zhong; Katharina Bürger; Anders Wallin; Kaj Blennow; Stefan J Teipel; Yong Shen; Harald Hampel
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease.
Brain : a journal of neurology 2008;131(Pt 5):1252-8.
2008: Ahmadul Kadir; Niels Andreasen; Ove Almkvist; Anders Wall; Anton Forsberg; Henry Willy Engler; Göran Hagman; Marie Lärksäter; Bengt Winblad; Henrik Zetterberg; Kaj Blennow; Bengt Långström; agneta nordberg
Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease.
Annals of neurology 2008;63(5):621-31.
2008: Igor Klyubin; Vicki Betts; Alfred T Welzel; Kaj Blennow; Henrik Zetterberg; Anders Wallin; Cynthia A Lemere; William K Cullen; Ying Peng; Thomas Wisniewski; Dennis J Selkoe; Roger Anwyl; Dominic M Walsh; Michael J Rowan
Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(16):4231-7.
2008: Erik Portelius; Henrik Zetterberg; Johan Gobom; Ulf Andreasson; Kaj Blennow
Targeted proteomics in Alzheimer's disease: focus on amyloid-beta.
Expert review of proteomics 2008;5(2):225-37.
2008: Karin Nylén; Martin Ost; Ludwig Z Csajbok; I Nilsson; C Hall; Kaj Blennow; Bengt Nellgård; Lars Rosengren
Serum levels of S100B, S100A1B and S100BB are all related to outcome after severe traumatic brain injury.
Acta neurochirurgica 2008;150(3):221-7; discussion 227.
2008: Harald Hampel; Katharina Bürger; Stefan J Teipel; Arun Bokde; Henrik Zetterberg; Kaj Blennow
Core candidate neurochemical and imaging biomarkers of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(1):38-48.
2008: Henrik Zetterberg; Kaj Blennow
Biological CSF markers of Alzheimer's disease.
Handbook of clinical neurology 2008;89():261-8.
2008: Peder Buchhave; Erik Stomrud; S Warkentin; Kaj Blennow; Lennart Minthon; Oskar Hansson
Cube copying test in combination with rCBF or CSF A beta 42 predicts development of Alzheimer's disease.
Dementia and geriatric cognitive disorders 2008;25(6):544-52.
2008: Mats Tullberg; Kaj Blennow; Jan-Eric Månsson; Pam Fredman; Magnus Tisell; Carsten Wikkelsö
Cerebrospinal fluid markers before and after shunting in patients with secondary and idiopathic normal pressure hydrocephalus.
Cerebrospinal fluid research 2008;5():9.
2008: K Höglund; Oskar Hansson; P Buchhave; Henrik Zetterberg; P Lewczuk; E Londos; Kaj Blennow; L Minthon; J Wiltfang
Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides.
Neuro-degenerative diseases 2008;5(5):268-76.
2008: R Anckarsäter; Henrik Zetterberg; J-E Månsson; Kaj Blennow; Henrik Anckarsäter
Non-neurological surgery results in a neurochemical stress response.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(3):397-9.
2007: Michael Ewers; Katharina Buerger; Stefan J Teipel; Philip scheltens; J Schröder; Raymond Zinkowski; Femke H Bouwman; Peter Schönknecht; Niki S M Schoonenboom; Niels Andreasen; Anders Wallin; John DeBernardis; Daniel Kerkman; Bernhard Heindl; Kaj Blennow; Harald Hampel
Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI.
Neurology 2007;69(24):2205-12.
2007: D R Gustafson; C Karlsson; Ingmar Skoog; L Rosengren; L Lissner; Kaj Blennow
Mid-life adiposity factors relate to blood-brain barrier integrity in late life.
Journal of internal medicine 2007;262(6):643-50.
2007: Niklas Mattsson; Ulla Rüetschi; Vladimir N Podust; Mats Stridsberg; Susann Li; Oluf Andersen; Sara Haghighi; Kaj Blennow; Henrik Zetterberg
Cerebrospinal fluid concentrations of peptides derived from chromogranin B and secretogranin II are decreased in multiple sclerosis.
Journal of neurochemistry 2007;103(5):1932-9.
2007: Henrik Zetterberg; Johan Jacobsson; L Rosengren; Kaj Blennow; Peter M Andersen
Cerebrospinal fluid neurofilament light levels in amyotrophic lateral sclerosis: impact of SOD1 genotype.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(12):1329-33.
2007: Henrik Zetterberg; Mona Pedersen; Karin Lind; Maria Svensson; Sindre Rolstad; Carl Eckerström; Steinar Syversen; Ulla-Britt Mattsson; Christina Ysander; Niklas Mattsson; Arto Nordlund; hugo vanderstichele; Eugeen Vanmechelen; Michael Jonsson; Ake Edman; Kaj Blennow; Anders Wallin
Intra-individual stability of CSF biomarkers for Alzheimer's disease over two years.
Journal of Alzheimer's disease : JAD 2007;12(3):255-60.
2007: Sandip Ray; Markus Britschgi; Charles Herbert; Yoshiko Takeda-Uchimura; Adam Boxer; Kaj Blennow; Leah F Friedman; Douglas Galasko; Marek Jutel; Anna Karydas; Jeffrey A Kaye; Jerzy Leszek; Bruce L Miller; Lennart Minthon; Joseph F Quinn; Gil Rabinovici; William H Robinson; Marwan Sabbagh; Yuen T So; D Larry Sparks; Massimo Tabaton; Jared R Tinklenberg; Jerome A Yesavage; Robert Tibshirani; Tony Wyss-Coray
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins.
Nature medicine 2007;13(11):1359-62.
2007: Erik Portelius; Ai Jun Tran; Ulf Andreasson; Rita Persson; Gunnar Brinkmalm; Henrik Zetterberg; Kaj Blennow; Ann Westman-Brinkmalm
Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry.
Journal of proteome research 2007;6(11):4433-9.
2007: Aina Agren-Wilsson; Annika Lekman; W Sjöberg; Lars Rosengren; Kaj Blennow; A Tommy Bergenheim; Jan Malm
CSF biomarkers in the evaluation of idiopathic normal pressure hydrocephalus.
Acta neurologica Scandinavica 2007;116(5):333-9.
2007: Henrietta M Nielsen; Lennart Minthon; Elisabet Londos; Kaj Blennow; Elena Miranda; J Perez; Damian C Crowther; David A Lomas; Sabina Janciauskiene
Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies.
Neurology 2007;69(16):1569-79.
2007: Pia Gudmundsson; Ingmar Skoog; Margda Waern; Kaj Blennow; Sigurdur Pálsson; Lars Rosengren; Deborah Gustafson
The relationship between cerebrospinal fluid biomarkers and depression in elderly women.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007;15(10):832-8.
2007: Rolf Anckarsäter; Henrik Zetterberg; Kaj Blennow; Henrik Anckarsäter
Association between thyroid hormone levels and monoaminergic neurotransmission during surgery.
Psychoneuroendocrinology 2007;32(8-10):1138-43.
2007: Henrik Zetterberg; Michael Jonsson; Abdullah Rasulzada; Cornel Popa; Ewa Styrud; Max Albert Hietala; Lars Rosengren; Anders Wallin; Kaj Blennow
No neurochemical evidence for brain injury caused by heading in soccer.
British journal of sports medicine 2007;41(9):574-7.
2007: Malin E Andersson; Annica Sjölander; Niels Andreasen; Lennart Minthon; Oskar Hansson; Nenad Bogdanovic; Christina Jern; Katarina Jood; Anders Wallin; Kaj Blennow; Henrik Zetterberg
Kinesin gene variability may affect tau phosphorylation in early Alzheimer's disease.
International journal of molecular medicine 2007;20(2):233-9.
2007: Sara F Hansson; Anja Hviid Simonsen; Henrik Zetterberg; Oluf Andersen; Sara Haghighi; Inger Fagerberg; Ulf Andréasson; Ann Westman-Brinkmalm; Anders Wallin; Ulla Rüetschi; Kaj Blennow
Cystatin C in cerebrospinal fluid and multiple sclerosis.
Annals of neurology 2007;62(2):193-6; discussion 205.
2007: Linda Paulson; Peter Martin; Elisabeth Ljung; Kaj Blennow; Pia Davidsson
Proteome analysis after co-administration of clozapine or haloperidol to MK-801-treated rats.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(7):885-91.
2007: Ulf Andreasson; Erik Portelius; Malin E Andersson; Kaj Blennow; Henrik Zetterberg
Aspects of beta-amyloid as a biomarker for Alzheimer's disease.
Biomarkers in medicine 2007;1(1):59-78.
2007: Madeleine Zetterberg; Gunnar Tasa; Mona Palmér; Erkki Juronen; Egle Toover; Kaj Blennow; Henrik Zetterberg
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.
Ophthalmic genetics 2007;28(2):47-50.
2007: Zhenyu Zhong; Michael Ewers; Stefan J Teipel; Katharina Bürger; Anders Wallin; Kaj Blennow; Ping He; Carrie McAllister; Harald Hampel; Yong Shen
Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.
Archives of general psychiatry 2007;64(6):718-26.
2007: Madeleine Zetterberg; Gunnar Tasa; Mona Palmér; Erkki Juronen; Pait Teesalu; Kaj Blennow; Henrik Zetterberg
Apolipoprotein E polymorphisms in patients with primary open-angle glaucoma.
American journal of ophthalmology 2007;143(6):1059-60.
2007: M Salud García-Ayllón; María-Ximena Silveyra; Niels Andreasen; Stephen Brimijoin; Kaj Blennow; Javier Sáez-Valero
Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease.
Journal of neurochemistry 2007;101(6):1701-11.
2007: Henrik Zetterberg; Max Albert Hietala; Anders Wallin; Kaj Blennow
[Guidelines for brain concussion in sports--how are they to be applied in boxing?].
Läkartidningen 2007;104(22):1715; author reply 1715-6.
2007: Kaj Blennow; Henrik Zetterberg; Lennart Minthon; Lars Lannfelt; Stig Strid; Peter Annas; Hans Basun; Niels Andreasen
Longitudinal stability of CSF biomarkers in Alzheimer's disease.
Neuroscience letters 2007;419(1):18-22.
2007: Hidenaga Yamamori; Sabiha Khatoon; Inge Grundke-Iqbal; Kaj Blennow; Michael Ewers; Harald Hampel; Khalid Iqbal
Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification.
Neuroscience letters 2007;418(2):186-9.
2007: Ulf Berggren; Matts Eriksson; Claudia Fahlke; Kaj Blennow; Jan Balldin
Different effects of smoking or use of smokeless tobacco on platelet MAO-B activity in type 1 alcohol-dependent subjects.
Alcohol and alcoholism (Oxford, Oxfordshire) 2007;42(3):267-71.
2007: Karin Nylén; Ludwig Z Csajbok; Martin Ost; Anas Rashid; Kaj Blennow; Bengt Nellgård; Lars Rosengren
Serum glial fibrillary acidic protein is related to focal brain injury and outcome after aneurysmal subarachnoid hemorrhage.
Stroke; a journal of cerebral circulation 2007;38(5):1489-94.
2007: Deborah R Gustafson; Ingmar Skoog; Lars Rosengren; Henrik Zetterberg; Kaj Blennow
Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older women.
Journal of neurology, neurosurgery, and psychiatry 2007;78(5):461-4.
2007: R Anckarsäter; N Vasic; L Jidéus; Marianne Kristiansson; Henrik Zetterberg; Kaj Blennow; Henrik Anckarsäter
Cerebrospinal fluid protein reactions during non-neurological surgery.
Acta neurologica Scandinavica 2007;115(4):254-9.
2007: Niklas Mattsson; Sara Haghighi; Oluf Andersen; Yuemang Yao; Lars Rosengren; Kaj Blennow; Domenico Pratico'; Henrik Zetterberg
Elevated cerebrospinal fluid F2-isoprostane levels indicating oxidative stress in healthy siblings of multiple sclerosis patients.
Neuroscience letters 2007;414(3):233-6.
2007: Mats Tullberg; Kaj Blennow; Jan-Eric Månsson; Pam Fredman; Magnus Tisell; Carsten Wikkelsö
Ventricular cerebrospinal fluid neurofilament protein levels decrease in parallel with white matter pathology after shunt surgery in normal pressure hydrocephalus.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(3):248-54.
2007: Anja Hviid Simonsen; James McGuire; Oskar Hansson; Henrik Zetterberg; Vladimir N Podust; Huw A Davies; Gunhild Waldemar; Lennart Minthon; Kaj Blennow
Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment.
Archives of neurology 2007;64(3):366-70.
2007: Mony J de Leon; Lisa Mosconi; Kaj Blennow; Susan Desanti; Raymond Zinkowski; Pankaj D Mehta; Domenico Pratico'; Wai Hon Tsui; LA Saint Louis; L Sobanska; Miroslaw Brys; Yongsheng Li; Kenneth Rich; J Rinne; Henry Rusinek
Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease.
Annals of the New York Academy of Sciences 2007;1097():114-45.
2007: Hillevi Englund; Göran Annerén; Jan Gustafsson; Ulrika Wester; Jens Wiltfang; Lars Lannfelt; Kaj Blennow; Kina Höglund
Increase in beta-amyloid levels in cerebrospinal fluid of children with Down syndrome.
Dementia and geriatric cognitive disorders 2007;24(5):369-74.
2007: Malin E Andersson; Madeleine Zetterberg; Gunnar Tasa; Mona Seibt-Palmér; Erkki Juronen; Pait Teesalu; Kaj Blennow; Henrik Zetterberg
Variability in the kinesin light chain 1 gene may influence risk of age-related cataract.
Molecular vision 2007;13():993-6.
2007: Erik Stomrud; Oskar Hansson; Kaj Blennow; Lennart Minthon; Elisabet Londos
Cerebrospinal fluid biomarkers predict decline in subjective cognitive function over 3 years in healthy elderly.
Dementia and geriatric cognitive disorders 2007;24(2):118-24.
2007: Kina Höglund; Kaj Blennow
Effect of HMG-CoA reductase inhibitors on beta-amyloid peptide levels: implications for Alzheimer's disease.
CNS drugs 2007;21(6):449-62.
2007: Oskar Hansson; Henrik Zetterberg; Peder Buchhave; Ulf Andreasson; Elisabet Londos; Lennart Minthon; Kaj Blennow
Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment.
Dementia and geriatric cognitive disorders 2007;23(5):316-20.
2007: Anja Hviid Simonsen; S F Hansson; U Ruetschi; James McGuire; Vladimir N Podust; Huw A Davies; P Mehta; Gunhild Waldemar; Henrik Zetterberg; Niels Andreasen; Anders Wallin; Kaj Blennow
Amyloid beta1-40 quantification in CSF: comparison between chromatographic and immunochemical methods.
Dementia and geriatric cognitive disorders 2007;23(4):246-50.
2007: Annika Thorsell; Erik Portelius; Kaj Blennow; Ann Westman-Brinkmalm
Evaluation of sample fractionation using micro-scale liquid-phase isoelectric focusing on mass spectrometric identification and quantitation of proteins in a SILAC experiment.
Rapid communications in mass spectrometry : RCM 2007;21(5):771-8.
2007: Christin Andersson; Kaj Blennow; Sven-Erik Johansson; Ove Almkvist; Peter Engfeldt; Maria Lindau; Maria Eriksdotter-Jönhagen
Differential CSF biomarker levels in APOE-epsilon4-positive and -negative patients with memory impairment.
Dementia and geriatric cognitive disorders 2007;23(2):87-95.
2006: Erik Portelius; Henrik Zetterberg; Ulf Andreasson; Gunnar Brinkmalm; Niels Andreasen; Anders Wallin; Ann Westman-Brinkmalm; Kaj Blennow
An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid.
Neuroscience letters 2006;409(3):215-9.
2006: Martin Ost; Karin Nylén; Ludwig Z Csajbok; A Olsson Ohrfelt; Mats Tullberg; Carsten Wikkelsö; P Nellgård; Lars Rosengren; Kaj Blennow; Bengt Nellgård
Initial CSF total tau correlates with 1-year outcome in patients with traumatic brain injury.
Neurology 2006;67(9):1600-4.
2006: Henrik Zetterberg; Max Albert Hietala; Michael Jonsson; Niels Andreasen; Ewa Styrud; Ingvar Karlsson; Ake Edman; Cornel Popa; Abdullah Rasulzada; Lars-Olof Wahlund; Pankaj D Mehta; Lars Rosengren; Kaj Blennow; Anders Wallin
Neurochemical aftermath of amateur boxing.
Archives of neurology 2006;63(9):1277-80.
2006: Ulf Berggren; Claudia Fahlke; Erik Aronsson; Aikaterini Karanti; Matts Eriksson; Kaj Blennow; Dag Steinar Thelle; Henrik Zetterberg; Jan Balldin
The taqI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small.
Alcohol and alcoholism (Oxford, Oxfordshire) 2006;41(5):479-85.
2006: Karin Nylén; Ludwig Z Csajbok; Martin Ost; A Rashid; Jan-Erik Karlsson; Kaj Blennow; Bengt Nellgård; Lars Rosengren
CSF -neurofilament correlates with outcome after aneurysmal subarachnoid hemorrhage.
Neuroscience letters 2006;404(1-2):132-6.
2006: Charley A Merrill; Michael Jonsson; Lennart Minthon; Hasse Ejnell; Hans C-son Silander; Kaj Blennow; Mats Karlsson; Arto Nordlund; Sindre Rolstad; Siegbert Warkentin; Elinor Ben-Menachem; Magnus Sjögren
Vagus nerve stimulation in patients with Alzheimer's disease: Additional follow-up results of a pilot study through 1 year.
The Journal of clinical psychiatry 2006;67(8):1171-8.
2006: Henrik Zetterberg; Kaj Blennow
Plasma Abeta in Alzheimer's disease--up or down?
Lancet neurology 2006;5(8):638-9.
2006: Kaj Blennow; Mony J de Leon; Henrik Zetterberg
Alzheimer's disease.
Lancet 2006;368(9533):387-403.
2006: Kaj Blennow; Henrik Zetterberg
Pinpointing plaques with PIB.
Nature medicine 2006;12(7):753-4; discussion 754.
2006: Matthias Riemenschneider; Kaj Blennow; Stefan Wagenpfeil; Niels Andreasen; Jonathan A Prince; Simon Laws; hans förstl; Alexander Kurz
The cathepsin D rs17571 polymorphism: effects on CSF tau concentrations in Alzheimer disease.
Human mutation 2006;27(6):532-7.
2006: A-M Nilselid; Pia Davidsson; Katarina Nägga; Niels Andreasen; Pam Fredman; Kaj Blennow
Clusterin in cerebrospinal fluid: analysis of carbohydrates and quantification of native and glycosylated forms.
Neurochemistry international 2006;48(8):718-28.
2006: Erik Portelius; Ann Westman-Brinkmalm; Henrik Zetterberg; Kaj Blennow
Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry.
Journal of proteome research 2006;5(4):1010-6.
2006: Oskar Hansson; Henrik Zetterberg; Peder Buchhave; Elisabet Londos; Kaj Blennow; Lennart Minthon
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study.
Lancet neurology 2006;5(3):228-34.
2006: Mia E-L Blomqvist; Chandra Reynolds; Hagit Katzov; Lars Feuk; Niels Andreasen; Nenad Bogdanovic; Kaj Blennow; Anthony J Brookes; Jonathan A Prince
Towards compendia of negative genetic association studies: an example for Alzheimer disease.
Human genetics 2006;119(1-2):29-37.
2006: Karin Nylén; Martin Ost; Ludwig Z Csajbok; I Nilsson; Kaj Blennow; Bengt Nellgård; Lars Rosengren
Increased serum-GFAP in patients with severe traumatic brain injury is related to outcome.
Journal of the neurological sciences 2006;240(1-2):85-91.
2006: hugo vanderstichele; Karen De Vreese; Kaj Blennow; Niels Andreasen; C J M Sindic; Adrian Ivanoiu; Harald Hampel; Katharina Bürger; Lucilla Parnetti; Alessia Lanari; Alessandro Padovani; Monica DiLuca; Miriam Bläser; Annika Ohrfelt Olsson; Hans Pottel; Frank Hulstaert; Eugeen Vanmechelen
Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2006;44(12):1472-80.
2006: Lars-Magnus Andersson; Lars Hagberg; Lars Rosengren; Dietmar Fuchs; Kaj Blennow; Magnus Gisslen
Normalisation of cerebrospinal fluid biomarkers parallels improvement of neurological symptoms following HAART in HIV dementia--case report.
BMC infectious diseases 2006;6():141.
2006: Kina Höglund; Anders Wallin; Kaj Blennow
Effect of statins on beta-amyloid metabolism in humans: potential importance for the development of senile plaques in Alzheimer's disease.
Acta neurologica Scandinavica. Supplementum 2006;185():87-92.
2006: M Kivipelto; A Solomon; Kaj Blennow; A G Olsson; Bengt Winblad
The new cholesterol controversy - a little bit of history repeating?
Acta neurologica Scandinavica. Supplementum 2006;185():1-2.
2006: Michelle M Mielke; Peter P Zandi; Kaj Blennow; Deborah Gustafson; Magnus Sjögren; Lars Rosengren; Ingmar Skoog
Low serum potassium in mid life associated with decreased cerebrospinal fluid Abeta42 in late life.
Alzheimer disease and associated disorders 2006;20(1):30-6.
2006: Anders Wallin; Kaj Blennow; Niels Andreasen; Lennart Minthon
CSF biomarkers for Alzheimer's Disease: levels of beta-amyloid, tau, phosphorylated tau relate to clinical symptoms and survival.
Dementia and geriatric cognitive disorders 2006;21(3):131-8.
2006: Hagit Katzov; Anna M Bennet; Kina Höglund; Björn Wiman; Dieter Lütjohann; Anthony J Brookes; Niels Andreasen; Kaj Blennow; Ulf de Faire; Jonathan A Prince
Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-beta 1-42 and plasma apolipoprotein levels.
Journal of human genetics 2006;51(3):171-9.
2006: Katharina Buerger; Markus Otto; Stefan J Teipel; Raymond Zinkowski; Kaj Blennow; John DeBernardis; Daniel Kerkman; Johannes Schröder; Peter Schönknecht; Lukas Cepek; Cheryl McCulloch; Hans-Jürgen Möller; Jens Wiltfang; Hans A Kretzschmar; Harald Hampel
Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease.
Neurobiology of aging 2006;27(1):10-5.
2005: Katharina Buerger; Stefan J Teipel; Raymond Zinkowski; Trey Sunderland; Niels Andreasen; Kaj Blennow; Michael Ewers; John DeBernardis; Yong Shen; Daniel Kerkman; Yansheng Du; Harald Hampel
Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment.
Neuroscience letters 2005;391(1-2):48-50.
2005: Linda K Nilsson; Klas R Linderholm; Göran Engberg; L Paulson; Kaj Blennow; Leif Lindström; Conny Nordin; A Karanti; P Persson; Sophie Erhardt
Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia.
Schizophrenia research 2005;80(2-3):315-22.
2005: Lars-Olof Wahlund; Ove Almkvist; Kaj Blennow; Knut Engedahl; Aki Johansson; Gunhild Waldemar; Henrike Wolf
Evidence-based evaluation of magnetic resonance imaging as a diagnostic tool in dementia workup.
Topics in magnetic resonance imaging : TMRI 2005;16(6):427-37.
2005: Kaj Blennow; Annica Johansson; Henrik Zetterberg
Diagnostic value of 14-3-3beta immunoblot and T-tau/P-tau ratio in clinically suspected Creutzfeldt-Jakob disease.
International journal of molecular medicine 2005;16(6):1147-9.
2005: Ulla Rüetschi; Henrik Zetterberg; Vladimir N Podust; Johan Gottfries; Susann Li; Anja Hviid Simonsen; James McGuire; Mats Karlsson; Lars Rymo; Huw Davies; Lennart Minthon; Kaj Blennow
Identification of CSF biomarkers for frontotemporal dementia using SELDI-TOF.
Experimental neurology 2005;196(2):273-81.
2005: Katharina Buerger; Michael Ewers; Niels Andreasen; Raymond Zinkowski; K Ishiguro; Eugeen Vanmechelen; Stefan J Teipel; Christian Graz; Kaj Blennow; Harald Hampel
Phosphorylated tau predicts rate of cognitive decline in MCI subjects: a comparative CSF study.
Neurology 2005;65(9):1502-3.
2005: Bruce J Brew; Louise Pemberton; Kaj Blennow; Anders Wallin; L Hagberg
CSF amyloid beta42 and tau levels correlate with AIDS dementia complex.
Neurology 2005;65(9):1490-2.
2005: Madeleine Zetterberg; Gunnar Tasa; Jonathan A Prince; Mona Palmér; Erkki Juronen; Siiri Veromann; Pait Teesalu; Jan-Olof Karlsson; Kaj Blennow; Henrik Zetterberg
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with cataract.
American journal of ophthalmology 2005;140(5):932-4.
2005: Khalid Iqbal; Michael Flory; Sabiha Khatoon; Hilkka Soininen; Tuula Pirttila; Maarit Lehtovirta; Irina Alafuzoff; Kaj Blennow; Niels Andreasen; Eugeen Vanmechelen; Inge Grundke-Iqbal
Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers.
Annals of neurology 2005;58(5):748-57.
2005: Kaj Blennow; Cornel Popa; Abdullah Rasulzada; Lennart Minthon; Anders Wallin; Henrik Zetterberg
[There is a strong evidence that professional boxing results in chronic brain damage. The more head punches during a boxer's career, the bigger is the risk].
Läkartidningen 2005;102(36):2468-70, 2472-5.
2005: Kaj Blennow
CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatment.
Expert review of molecular diagnostics 2005;5(5):661-72.
2005: hugo vanderstichele; Geert De Meyer; Niels Andreasen; Vesna Kostanjevecki; Anders Wallin; Annika Olsson; Kaj Blennow; Eugeen Vanmechelen
Amino-truncated beta-amyloid42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment.
Clinical chemistry 2005;51(9):1650-60.
2005: Kina Höglund; Steinar Syversen; Piotr Lewczuk; Anders Wallin; Jens Wiltfang; Kaj Blennow
Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;164(2):205-14.
2005: Henrik Anckarsäter; Anders Forsman; Kaj Blennow
Increased CSF/serum albumin ratio: a recurrent finding in violent offenders.
Acta neurologica Scandinavica 2005;112(1):48-50.
2005: Mia E-L Blomqvist; Katy Chalmers; Niels Andreasen; Nenad Bogdanovic; Gordon K Wilcock; Nigel J Cairns; Lars Feuk; Anthony J Brookes; Seth Love; Kaj Blennow; Pat Kehoe; Jonathan A Prince
Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
Neurobiology of aging 2005;26(6):795-802.
2005: Niels Andreasen; Kaj Blennow
CSF biomarkers for mild cognitive impairment and early Alzheimer's disease.
Clinical neurology and neurosurgery 2005;107(3):165-73.
2005: Henrik Zetterberg; Anna-Lena Hammarin; Petra Nilsson; Elsa Andersson; Börje Lind; Kaj Blennow
[New investigations in suspected Creutzfeldt-Jakob disease. Analysis of 14-3-3 protein and T-tau in cerebrospinal fluid for safer diagnosis].
Läkartidningen 2005;102(12-13):956-8, 960-1.
2005: Annika Olsson; hugo vanderstichele; Niels Andreasen; Geert De Meyer; Anders Wallin; Björn Holmberg; Lars Rosengren; Eugeen Vanmechelen; Kaj Blennow
Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology.
Clinical chemistry 2005;51(2):336-45.
2005: Annica Johansson; Henrik Zetterberg; Anna Zettergren; Hans Nissbrandt; Kaj Blennow
TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.
Neuro-degenerative diseases 2005;2(1):28-35.
2005: Ann Westman-Brinkmalm; Gösta Karlsson; Lena M Brive; Kristina Hedberg-Fogel; Rita Persson; Hasse Karlsson; Rolf Ekman; Kaj Blennow
Analysis of proteins from a glioma cell line by using micro-scale solution isoelectric focusing in combination with liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 2005;19(24):3651-8.
2005: Annica Johansson; Henrik Zetterberg; Harald Hampel; Katharina Buerger; Jonathan A Prince; Lennart Minthon; Lars-Olof Wahlund; Kaj Blennow
Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2005;20(6):367-74.
2005: Magnus Sjögren; Kaj Blennow
The link between cholesterol and Alzheimer's disease.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2005;6(2):85-97.
2005: Jens Wiltfang; Piotr Lewczuk; Peter Riederer; Edna Grünblatt; Christoph Hock; Philip scheltens; Harald Hampel; hugo vanderstichele; Khalid Iqbal; Douglas Galasko; Lars Lannfelt; Markus Otto; Hermann Esselmann; Andreas Wolfram Henkel; Johannes Kornhuber; Kaj Blennow
Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2005;6(2):69-84.
2005: K Hoglund; K M Thelen; Steinar Syversen; M Sjogren; K von Bergmann; Anders Wallin; Eugeen Vanmechelen; hugo vanderstichele; D Lutjohann; Kaj Blennow
The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 2005;19(5-6):256-65.
2005: Katarina Nagga; Jorge Garcia; Henrik Zetterberg; Kaj Blennow; Johan Gottfries; Jan Marcusson
Evaluation of factors of importance for clinical dementia diagnosis.
Dementia and geriatric cognitive disorders 2005;19(5-6):289-98.
2005: Marie Molander-Melin; Kaj Blennow; Nenad Bogdanovic; Birgitta Dellheden; Jan-Eric Månsson; Pam Fredman
Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains.
Journal of neurochemistry 2005;92(1):171-82.
2004: Harald Hampel; Kaj Blennow
CSF tau and β-amyloid as biomarkers for mild cognitive impairment.
Dialogues in clinical neuroscience 2004;6(4):379-90.
2004: Henrik Zetterberg; Kaj Blennow
Elevated total tau/phospho-tau ratio in autopsy-proven Creutzfeldt-Jakob disease with negative 14-3-3 test results.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2004;25(5):301-2.
2004: Henrik Soderstrom; Kaj Blennow; Anders Forsman; Jyrki Liesivuori; Sirpa Pennanen; J Tiihonen
A controlled study of tryptophan and cortisol in violent offenders.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(12):1605-10.
2004: Elisabeth Strandhagen; Henrik Zetterberg; Nibia Aires; Mona Palmér; Lars Rymo; Kaj Blennow; Dag Steinar Thelle
The apolipoprotein E polymorphism and the cholesterol-raising effect of coffee.
Lipids in health and disease 2004;3():26.
2004: Linda Paulson; Peter Martin; Elisabeth Ljung; Kaj Blennow; Pia Davidsson
Effects on rat thalamic proteome by acute and subchronic MK-801-treatment.
European journal of pharmacology 2004;505(1-3):103-9.
2004: Hagit Katzov; Anna M Bennet; Pat Kehoe; Björn Wiman; Margaret Gatz; Kaj Blennow; Boris Lenhard; Nancy L Pedersen; Ulf de Faire; Jonathan A Prince
A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity.
Human molecular genetics 2004;13(21):2647-57.
2004: Henrik Zetterberg; Niels Andreasen; Kaj Blennow
Increased cerebrospinal fluid levels of transforming growth factor-beta1 in Alzheimer's disease.
Neuroscience letters 2004;367(2):194-6.
2004: Bengt Winblad; K Palmer; Miia Kivipelto; Vesna Jelic; Laura Fratiglioni; Lars-Olof Wahlund; agneta nordberg; Lars Bäckman; Marilyn S Albert; O Almkvist; Hiroyuki Arai; Hans Basun; Kaj Blennow; Mony J de Leon; Charles DeCarli; Timo Erkinjuntti; Ezio Giacobini; C Graff; John Hardy; C Jack; A Jorm; K Ritchie; C.M. Duijn; P Visser; Ronald C. Petersen
Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.
Journal of internal medicine 2004;256(3):240-6.
2004: Kaj Blennow
CSF biomarkers for mild cognitive impairment.
Journal of internal medicine 2004;256(3):224-34.
2004: Magnus Sjögren; S Folkesson; Kaj Blennow; Elisabeth Tarkowski
Increased intrathecal inflammatory activity in frontotemporal dementia: pathophysiological implications.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1107-11.
2004: Annika Olsson; Ludwig Z Csajbok; Martin Ost; Kina Höglund; Karin Nylén; Lars Rosengren; Bengt Nellgård; Kaj Blennow
Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury.
Journal of neurology 2004;251(7):870-6.
2004: Andrea Schmitt; Katrin Wilczek; Kaj Blennow; Athanasios Maras; Alexander Jatzko; Georg A Petroianu; Dieter F Braus; Wagner F Gattaz
Altered thalamic membrane phospholipids in schizophrenia: a postmortem study.
Biological psychiatry 2004;56(1):41-5.
2004: Henrik Ryberg; Ann-Sofi Söderling; Pia Davidsson; Kaj Blennow; Kenneth Caidahl; Henrik Ryberg
Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimer's disease.
Neurochemistry international 2004;45(1):57-62.
2004: Harald Hampel; Stefan J Teipel; T Fuchsberger; Niels Andreasen; J Wiltfang; M Otto; Yong Shen; Richard Dodel; Yansheng Du; Martin R Farlow; Hans-Jürgen Möller; Kaj Blennow; Katharina Buerger
Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment.
Molecular psychiatry 2004;9(7):705-10.
2004: Jonathan A Prince; Henrik Zetterberg; Niels Andreasen; Jan Marcusson; Kaj Blennow
APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.
Neurology 2004;62(11):2116-8.
2004: Elisabeth Strandhagen; Henrik Zetterberg; Nibia Aires; Mona Palmér; Lars Rymo; Kaj Blennow; Sverre Landaas; Dag Steinar Thelle
The methylenetetrahydrofolate reductase C677T polymorphism is a major determinant of coffee-induced increase of plasma homocysteine: a randomized placebo controlled study.
International journal of molecular medicine 2004;13(6):811-5.
2004: Mia E-L Blomqvist; Peter A Silburn; Daniel D Buchanan; Niels Andreasen; Kaj Blennow; Nancy L Pedersen; Anthony J Brookes; George D Mellick; Jonathan A Prince
Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease.
Neurogenetics 2004;5(2):115-9.
2004: Madeleine Zetterberg; Henrik Zetterberg; Mona Palmér; Lars Rymo; Kaj Blennow; Gunnar Tasa; Erkki Juronen; Siiri Veromann; Pait Teesalu; J-O Karlsson; K Höglund
Apolipoprotein E polymorphism in patients with cataract.
The British journal of ophthalmology 2004;88(5):716-8.
2004: Björn Regland; L Abrahamsson; Kaj Blennow; B Grenfeldt; Carl-Gerhard Gottfries
CSF-methionine is elevated in psychotic patients.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(5):631-40.
2004: Annica Johansson; Hagit Katzov; Henrik Zetterberg; Lars Feuk; Boo Johansson; Nenad Bogdanovic; Niels Andreasen; Boris Lenhard; Anthony J Brookes; Nancy L Pedersen; Kaj Blennow; Jonathan A Prince
Variants of CYP46A1 may interact with age and APOE to influence CSF Abeta42 levels in Alzheimer's disease.
Human genetics 2004;114(6):581-7.
2004: Kaj Blennow
Cerebrospinal fluid protein biomarkers for Alzheimer's disease.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(2):213-25.
2004: Mia E-L Blomqvist; Niels Andreasen; Nenad Bogdanovic; Kaj Blennow; Anthony J Brookes; Jonathan A Prince
Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease.
Neuroscience letters 2004;358(3):220-2.
2004: Hagit Katzov; Katy Chalmers; Juni Palmgren; Niels Andreasen; Boo Johansson; Nigel J Cairns; Margaret Gatz; Gordon K Wilcock; Seth Love; Nancy L Pedersen; Anthony J Brookes; Kaj Blennow; Pat Kehoe; Jonathan A Prince
Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.
Human mutation 2004;23(4):358-67.
2004: Pat Kehoe; Hagit Katzov; Niels Andreasen; Margaret Gatz; Gordon K Wilcock; Nigel J Cairns; Juni Palmgren; Ulf de Faire; Anthony J Brookes; Nancy L Pedersen; Kaj Blennow; Jonathan A Prince
Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease.
Human genetics 2004;114(5):478-83.
2004: Kina Höglund; Olov Wiklund; hugo vanderstichele; Oliver Eikenberg; Eugeen Vanmechelen; Kaj Blennow
Plasma levels of beta-amyloid(1-40), beta-amyloid(1-42), and total beta-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins.
Archives of neurology 2004;61(3):333-7.
2004: Linda Paulson; Peter Martin; Carol L Nilsson; Elisabeth Ljung; Ann Westman-Brinkmalm; Kaj Blennow; Pia Davidsson
Comparative proteome analysis of thalamus in MK-801-treated rats.
Proteomics 2004;4(3):819-25.
2004: Harald Hampel; A Mitchell; Kaj Blennow; R A Frank; Sylvia Brettschneider; Lars Weller; Hans-Jürgen Möller
Core biological marker candidates of Alzheimer's disease - perspectives for diagnosis, prediction of outcome and reflection of biological activity.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(3):247-72.
2004: Eleftherios P Diamandis; Andreas Scorilas; Tadaaki Kishi; Kaj Blennow; Liu-Ying Luo; Antoninus Soosaipillai; Alfred W Rademaker; Magnus Sjogren
Altered kallikrein 7 and 10 concentrations in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia.
Clinical biochemistry 2004;37(3):230-7.
2004: Kaj Blennow; Bengt Nellgård
Amyloid beta 1-42 and tau in cerebrospinal fluid after severe traumatic brain injury.
Neurology 2004;62(1):159; author reply 159-60.
2004: Estelle Trysberg; Kaj Blennow; Olof Zachrisson; Andrej Tarkowski
Intrathecal levels of matrix metalloproteinases in systemic lupus erythematosus with central nervous system engagement.
Arthritis research & therapy 2004;6(6):R551-6.
2004: Estelle Trysberg; Kina Höglund; Elisabet Svenungsson; Kaj Blennow; Andrej Tarkowski
Decreased levels of soluble amyloid beta-protein precursor and beta-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus.
Arthritis research & therapy 2004;6(2):R129-36.
2004: Andrew McCaddon; Kaj Blennow; Peter Hudson; Alan Hughes; Joan Barber; Rob Gray; Gareth Davies; John Williams; Jennifer Duguid; Alwyn Lloyd; Steve Tandy; Marge Everall; Howard Cattell; Anne McCaddon; Dick Ellis; Mona Palmer; Nenad Bogdanovic; Carl-Gerhard Gottfries; Henrik Zetterberg; Lars Rymo; Björn Regland
Transcobalamin polymorphism and serum holo-transcobalamin in relation to Alzheimer's disease.
Dementia and geriatric cognitive disorders 2004;17(3):215-21.
2004: Harald Hampel; Katharina Buerger; Raymond Zinkowski; Stefan J Teipel; Alexander Goernitz; Niels Andreasen; Magnus Sjoegren; John DeBernardis; Daniel Kerkman; Koichi Ishiguro; Hideto Ohno; Eugeen Vanmechelen; hugo vanderstichele; Cheryl McCulloch; Hans-Jurgen Moller; Peter Davies; Kaj Blennow
Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.
Archives of general psychiatry 2004;61(1):95-102.
2004: Magnus Tisell; Mats Tullberg; Jan-Eric Månsson; Pam Fredman; Kaj Blennow; Carsten Wikkelsø
Differences in cerebrospinal fluid dynamics do not affect the levels of biochemical markers in ventricular CSF from patients with aqueductal stenosis and idiopathic normal pressure hydrocephalus.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2004;11(1):17-23.
2003: R Yhede; Kaj Blennow; Anders Forsman; Henrik Soderstrom
The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans.
Journal of neural transmission (Vienna, Austria : 1996) 2003;110(12):1369-73.
2003: Henrik Zetterberg; Lars-Olof Wahlund; Kaj Blennow
Cerebrospinal fluid markers for prediction of Alzheimer's disease.
Neuroscience letters 2003;352(1):67-9.
2003: Jonathan A Prince; Lars Feuk; Harvest F Gu; Boo Johansson; Margaret Gatz; Kaj Blennow; Anthony J Brookes
Genetic variation in a haplotype block spanning IDE influences Alzheimer disease.
Human mutation 2003;22(5):363-71.
2003: Maja Puchades; Sara Folkesson Hansson; Carol L Nilsson; Niels Andreasen; Kaj Blennow; Pia Davidsson
Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease.
Brain research. Molecular brain research 2003;118(1-2):140-6.
2003: Anders Johansson; Anders Larsson; Ingela Nygren; Kaj Blennow; Håkan Askmark
Increased serum and cerebrospinal fluid FGF-2 levels in amyotrophic lateral sclerosis.
Neuroreport 2003;14(14):1867-9.
2003: Niels Andreasen; Magnus Sjögren; Kaj Blennow
CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta42.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2003;4(4):147-55.
2003: Kaj Blennow; Harald Hampel
CSF markers for incipient Alzheimer's disease.
Lancet neurology 2003;2(10):605-13.
2003: Annika Olsson; Kina Höglund; Magnus Sjögren; Niels Andreasen; Lennart Minthon; Lars Lannfelt; Katharina Buerger; Hans-Jürgen Möller; Harald Hampel; Pia Davidsson; Kaj Blennow
Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients.
Experimental neurology 2003;183(1):74-80.
2003: Elisabeth Tarkowski; Niels Andreasen; Andrej Tarkowski; Kaj Blennow
Intrathecal inflammation precedes development of Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2003;74(9):1200-5.
2003: Henrik Zetterberg; Alexandros Zafiropoulos; Demetrios A Spandidos; Lars Rymo; Kaj Blennow
Gene-gene interaction between fetal MTHFR 677C>T and transcobalamin 776C>G polymorphisms in human spontaneous abortion.
Human reproduction (Oxford, England) 2003;18(9):1948-50.
2003: Elisabeth Tarkowski; Ann Marie Liljeroth; Lennart Minthon; Andrej Tarkowski; Anders Wallin; Kaj Blennow
Cerebral pattern of pro- and anti-inflammatory cytokines in dementias.
Brain research bulletin 2003;61(3):255-60.
2003: Kaj Blennow; Eugeen Vanmechelen
CSF markers for pathogenic processes in Alzheimer's disease: diagnostic implications and use in clinical neurochemistry.
Brain research bulletin 2003;61(3):235-42.
2003: Deborah Gustafson; Elisabet Rothenberg; Kaj Blennow; Bertil Steen; Ingmar Skoog
An 18-year follow-up of overweight and risk of Alzheimer disease.
Archives of internal medicine 2003;163(13):1524-8.
2003: Pia Davidsson; A Brinkmalm; Gösta Karlsson; Rita Persson; Maria Lindbjer; Maja Puchades; S Folkesson; Linda Paulson; Annika Dahl; Lars Rymo; Jerzy Silberring; Rolf Ekman; Kaj Blennow
Clinical mass spectrometry in neuroscience. Proteomics and peptidomics.
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(5):681-8.
2003: Henrik Zetterberg; Ebba Nexö; Björn Regland; Lennart Minthon; Roberta Boson; Mona Palmér; Lars Rymo; Kaj Blennow
The transcobalamin (TC) codon 259 genetic polymorphism influences holo-TC concentration in cerebrospinal fluid from patients with Alzheimer disease.
Clinical chemistry 2003;49(7):1195-8.
2003: Henrik Soderstrom; Kaj Blennow; Anna-Kari Sjodin; Anders Forsman
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
Journal of neurology, neurosurgery, and psychiatry 2003;74(7):918-21.
2003: Magnus Sjögren; Niels Andreasen; Kaj Blennow
Advances in the detection of Alzheimer's disease-use of cerebrospinal fluid biomarkers.
Clinica chimica acta; international journal of clinical chemistry 2003;332(1-2):1-10.
2003: Javier Sáez-Valero; Lisa R Fodero; M Sjögren; Niels Andreasen; Serena Amici; Virgilio Gallai; hugo vanderstichele; E Vanmechelen; Lucilla Parnetti; Kaj Blennow; David Small
Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease.
Journal of neuroscience research 2003;72(4):520-6.
2003: Henrik Zetterberg; Mona Palmér; Cecilia Boreström; Lars Rymo; Kaj Blennow
The transcobalamin codon 259 polymorphism should be designated 776C>G, not 775G>C.
Blood 2003;101(9):3749-50; author reply 3750-1.
2003: Pat Kehoe; Hagit Katzov; Lars Feuk; Anna M Bennet; Boo Johansson; Björn Wiman; Ulf de Faire; Nigel J Cairns; Gordon K Wilcock; Anthony J Brookes; Kaj Blennow; Jonathan A Prince
Haplotypes extending across ACE are associated with Alzheimer's disease.
Human molecular genetics 2003;12(8):859-67.
2003: Annica Johansson; Harald Hampel; Frank Faltraco; Katharina Buerger; Lennart Minthon; Nenad Bogdanovic; M Sjögren; Henrik Zetterberg; L Forsell; L Lilius; Lars-Olof Wahlund; Lars Rymo; Jonathan A Prince; Kaj Blennow
Increased frequency of a new polymorphism in the cell division cycle 2 (cdc2) gene in patients with Alzheimer's disease and frontotemporal dementia.
Neuroscience letters 2003;340(1):69-73.
2003: Javier Sáez-Valero; Mercedes Costell; Magnus Sjögren; Niels Andreasen; Kaj Blennow; Juan M Luque
Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer's disease.
Journal of neuroscience research 2003;72(1):132-6.
2003: Lars-Olof Wahlund; Kaj Blennow
Cerebrospinal fluid biomarkers for disease stage and intensity in cognitively impaired patients.
Neuroscience letters 2003;339(2):99-102.
2003: E Stefanova; Kaj Blennow; Ove Almkvist; Ewa Hellström-Lindahl; agneta nordberg
Cerebral glucose metabolism, cerebrospinal fluid-beta-amyloid1-42 (CSF-Abeta42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients.
Neuroscience letters 2003;338(2):159-63.
2003: Dorothea Strozyk; Kaj Blennow; Lon R White; Lenore J Launer
CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study.
Neurology 2003;60(4):652-6.
2003: Linda Paulson; Peter Martin; Anders Persson; Carol L Nilsson; Elisabeth Ljung; Ann Westman-Brinkmalm; Peter S Eriksson; Kaj Blennow; Pia Davidsson
Comparative genome- and proteome analysis of cerebral cortex from MK-801-treated rats.
Journal of neuroscience research 2003;71(4):526-33.
2003: Anders Hamberger; Ying-Lai Huang; Hong Zhu; Feng Bao; Mei Ding; Kaj Blennow; Annika Olsson; Hans-Arne Hansson; David C Viano; Kenneth G Haglid
Redistribution of neurofilaments and accumulation of beta-amyloid protein after brain injury by rotational acceleration of the head.
Journal of neurotrauma 2003;20(2):169-78.
2003: Björn Holmberg; Bo Johnels; Kaj Blennow; Lars Rosengren
Cerebrospinal fluid Abeta42 is reduced in multiple system atrophy but normal in Parkinson's disease and progressive supranuclear palsy.
Movement disorders : official journal of the Movement Disorder Society 2003;18(2):186-90.
2003: Anders Wallin; Magnus Sjögren; Kaj Blennow; Pia Davidsson
Decreased cerebrospinal fluid acetylcholinesterase in patients with subcortical ischemic vascular dementia.
Dementia and geriatric cognitive disorders 2003;16(4):200-7.
2003: Martin Lehmann; Björn Regland; Kaj Blennow; Carl-Gerhard Gottfries
Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment.
Dementia and geriatric cognitive disorders 2003;16(3):145-50.
2003: Yong-Xin Sun; Lennart Minthon; Anders Wallmark; Siegbert Warkentin; Kaj Blennow; Sabina Janciauskiene
Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 2003;16(3):136-44.
2003: Annika Olsson; Eugeen Vanmechelen; hugo vanderstichele; Pia Davidsson; Kaj Blennow
Unaltered plasma levels of beta-amyloid(1-40) and beta-amyloid(1-42) upon stimulation of human platelets.
Dementia and geriatric cognitive disorders 2003;16(2):93-7.
2003: Magnus Sjögren; Kina Gustafsson; Steinar Syversen; Annika Olsson; Ake Edman; Pia Davidsson; Anders Wallin; Kaj Blennow
Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein.
Dementia and geriatric cognitive disorders 2003;16(1):25-30.
2003: Niels Andreasen; Eugeen Vanmechelen; hugo vanderstichele; Pia Davidsson; Kaj Blennow
Cerebrospinal fluid levels of total-tau, phospho-tau and A beta 42 predicts development of Alzheimer's disease in patients with mild cognitive impairment.
Acta neurologica Scandinavica. Supplementum 2003;179():47-51.
2003: Ingmar Skoog; Pia Davidsson; O Aevarsson; hugo vanderstichele; Eugeen Vanmechelen; Kaj Blennow
Cerebrospinal fluid beta-amyloid 42 is reduced before the onset of sporadic dementia: a population-based study in 85-year-olds.
Dementia and geriatric cognitive disorders 2003;15(3):169-76.
2003: Lars Feuk; Jonathan A Prince; Kaj Blennow; Anthony J Brookes
Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease.
Human mutation 2003;21(1):53-60.
2002: Pia Davidsson; Magnus Sjögren; Niels Andreasen; Maria Lindbjer; Carol L Nilsson; Ann Westman-Brinkmalm; Kaj Blennow
Studies of the pathophysiological mechanisms in frontotemporal dementia by proteome analysis of CSF proteins.
Brain research. Molecular brain research 2002;109(1-2):128-33.
2002: Henrik Zetterberg; Björn Regland; Mona Palmér; Lars Rymo; Alexandros Zafiropoulos; Demetrios A Arvanitis; Demetrios A Spandidos; Kaj Blennow
The transcobalamin codon 259 polymorphism influences the risk of human spontaneous abortion.
Human reproduction (Oxford, England) 2002;17(12):3033-6.
2002: Henrik Zetterberg; Antonio Coppola; Armando D'Angelo; Mona Palmér; Lars Rymo; Kaj Blennow
No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyperhomocysteinemia in thrombotic disease.
Thrombosis research 2002;108(2-3):127-31.
2002: Ulf Berggren; Matts Eriksson; Claudia Fahlke; Kaj Blennow; Jan Balldin
Platelet monoamine oxidase B in family history positive and family history negative type 1 alcohol-dependent subjects.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(6):577-80.
2002: Lucilla Parnetti; Serena Amici; Alessia Lanari; C Romani; Cinzia Antognelli; Niels Andreasen; L Minthon; P Davidsson; Hans Pottel; Kaj Blennow; Virgilio Gallai
Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2002;23 Suppl 2():S95-6.
2002: Katharina Buerger; Stefan J Teipel; Raymond Zinkowski; Kaj Blennow; Hiroyuki Arai; Rolf Engel; Klaus Hofmann-Kiefer; Cheryl McCulloch; U Ptok; Reinhard Heun; Niels Andreasen; John DeBernardis; Daniel Kerkman; H- J Moeller; Peter Davies; Harald Hampel
CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects.
Neurology 2002;59(4):627-9.
2002: Katharina Buerger; Raymond Zinkowski; Stefan J Teipel; Tero Tapiola; Hiroyuki Arai; Kaj Blennow; Niels Andreasen; Klaus Hofmann-Kiefer; John DeBernardis; Daniel Kerkman; Cheryl McCulloch; Russell Kohnken; Frank Padberg; Tuula Pirttilä; Mark B Schapiro; Stanley I Rapoport; Hans-Jürgen Möller; Peter Davies; Harald Hampel
Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.
Archives of neurology 2002;59(8):1267-72.
2002: Niels Andreasen; Kaj Blennow
Beta-amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease.
Peptides 2002;23(7):1205-14.
2002: Ulf Berggren; Matts Eriksson; Claudia Fahlke; Kaj Blennow; Anders Sundkler; Jan Balldin
Platelet monoamine oxidase-B activity in type 1 alcohol-dependent subjects in sustained full remission.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(4):340-3.
2002: Henrik Zetterberg; Mona Palmér; Anne Ricksten; Judes Poirier; Lars Palmqvist; Lars Rymo; Alexandros Zafiropoulos; Demetrios A Arvanitis; Demetrios A Spandidos; Kaj Blennow
Influence of the apolipoprotein E epsilon4 allele on human embryonic development.
Neuroscience letters 2002;324(3):189-92.
2002: Magnus Sjögren; Kaj Blennow
[A new putative principle for diagnosis of Creutzfeldt-Jakob disease].
Läkartidningen 2002;99(21):2382-4.
2002: Mikael Landén; Pia Davidsson; Carl-Gerhard Gottfries; Jan-Eric Månsson; Kaj Blennow
Reduction of the synaptophysin level but normal levels of glycerophospholipids in the gyrus cinguli in schizophrenia.
Schizophrenia research 2002;55(1-2):83-8.
2002: Pia Davidsson; Ann Westman-Brinkmalm; Carol L Nilsson; Maria Lindbjer; Linda Paulson; Niels Andreasen; Magnus Sjögren; Kaj Blennow
Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients.
Neuroreport 2002;13(5):611-5.
2002: Elisabeth Tarkowski; Razao Issa; Magnus Sjögren; Anders Wallin; Kaj Blennow; Andrej Tarkowski; Pat Kumar
Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia.
Neurobiology of aging 2002;23(2):237-43.
2002: Henrik Zetterberg; Björn Regland; Mona Palmér; Anne Ricksten; Lars Palmqvist; Lars Rymo; Demetrios A Arvanitis; Demetrios A Spandidos; Kaj Blennow
Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos.
European journal of human genetics : EJHG 2002;10(2):113-8.
2002: Pia Davidsson; S Folkesson; M Christiansson; Maria Lindbjer; B Dellheden; Kaj Blennow; Ann Westman-Brinkmalm
Identification of proteins in human cerebrospinal fluid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation mass spectrometry.
Rapid communications in mass spectrometry : RCM 2002;16(22):2083-8.
2002: Magnus Sjögren; Carsten Wikkelsö; Svante Ostling; Anders Wallin; Kaj Blennow
Biological correlates of clinical subgroups of Alzheimer's disease.
Dementia and geriatric cognitive disorders 2002;14(4):191-7.
2002: Katarina Nägga; Johan Gottfries; Kaj Blennow; Jan Marcusson
Cerebrospinal fluid phospho-tau, total tau and beta-amyloid(1-42) in the differentiation between Alzheimer's disease and vascular dementia.
Dementia and geriatric cognitive disorders 2002;14(4):183-90.
2002: Aleksander A Mathé; Hans Agren; Anders Wallin; Kaj Blennow
Calcitonin gene-related peptide and calcitonin in the CSF of patients with dementia and depression: possible disease markers.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(1):41-8.
2002: Magnus Sjögren; Pia Davidsson; Anders Wallin; Ann-Kathrine Granérus; Eva Grundström; Håkan Askmark; Eugeen Vanmechelen; Kaj Blennow
Decreased CSF-beta-amyloid 42 in Alzheimer's disease and amyotrophic lateral sclerosis may reflect mismetabolism of beta-amyloid induced by disparate mechanisms.
Dementia and geriatric cognitive disorders 2002;13(2):112-8.
2002: Ingrid Sundman-Eriksson; Kaj Blennow; Pia Davidsson; Anna-Karin Dandenell; Jan Marcusson
Increased [(3)H]tiagabine binding to GAT-1 in the cingulate cortex in schizophrenia.
Neuropsychobiology 2002;45(1):7-11.
2001: Carol L Nilsson; A Brinkmalm; L Minthon; Kaj Blennow; Rolf Ekman
Processing of neuropeptide Y, galanin, and somatostatin in the cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia.
Peptides 2001;22(12):2105-12.
2001: Andrew McCaddon; Kaj Blennow; Peter Hudson; Björn Regland; Diane Hill
Transcobalamin polymorphism and homocysteine.
Blood 2001;98(12):3497-9.
2001: M Sjögren; Magnus Gisslen; Eugeen Vanmechelen; Kaj Blennow
Low cerebrospinal fluid beta-amyloid 42 in patients with acute bacterial meningitis and normalization after treatment.
Neuroscience letters 2001;314(1-2):33-6.
2001: Sophie Erhardt; Kaj Blennow; Conny Nordin; Elisabeth Skogh; Leif Lindström; Göran Engberg
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia.
Neuroscience letters 2001;313(1-2):96-8.
2001: Magnus Sjögren; M Blomberg; Michael Jonsson; Lars-Olof Wahlund; Ake Edman; Karin Lind; Lars Rosengren; Kaj Blennow; Anders Wallin
Neurofilament protein in cerebrospinal fluid: a marker of white matter changes.
Journal of neuroscience research 2001;66(3):510-6.
2001: Björn Regland; W Lehmann; I Abedini; Kaj Blennow; Michael Jonsson; Ingvar Karlsson; Magnus Sjögren; Anders Wallin; M Xilinas; Carl-Gerhard Gottfries
Treatment of Alzheimer's disease with clioquinol.
Dementia and geriatric cognitive disorders 2001;12(6):408-14.
2001: Eugeen Vanmechelen; hugo vanderstichele; Frank Hulstaert; Niels Andreasen; L Minthon; Bengt Winblad; P Davidsson; Kaj Blennow
Cerebrospinal fluid tau and beta-amyloid(1-42) in dementia disorders.
Mechanisms of ageing and development 2001;122(16):2005-11.
2001: M Sjögren; hugo vanderstichele; Hans Agren; Olof Zachrisson; Mikael Edsbagge; Carsten Wikkelsø; Ingmar Skoog; Anders Wallin; Lars-Olof Wahlund; J Marcusson; Katarina Nägga; Niels Andreasen; P Davidsson; Eugeen Vanmechelen; Kaj Blennow
Tau and Abeta42 in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values.
Clinical chemistry 2001;47(10):1776-81.
2001: Niels Andreasen; Johan Gottfries; Eugeen Vanmechelen; hugo vanderstichele; P Davidson; Kaj Blennow; L Rosengren; K Blennow
Evaluation of CSF biomarkers for axonal and neuronal degeneration, gliosis, and beta-amyloid metabolism in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2001;71(4):557-8.
2001: Elisabeth Tarkowski; Ann Marie Liljeroth; Lennart Minthon; Kaj Blennow
Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2001;12(5):314-7.
2001: Kaj Blennow; E Vanmechelen; Harald Hampel
CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease.
Molecular neurobiology 2001;24(1-3):87-97.
2001: Magnus Sjögren; Pia Davidsson; Johan Gottfries; hugo vanderstichele; Ake Edman; Eugeen Vanmechelen; Anders Wallin; Kaj Blennow
The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process.
Dementia and geriatric cognitive disorders 2001;12(4):257-64.
2001: Pia Davidsson; Nenad Bogdanovic; Lars Lannfelt; Kaj Blennow
Reduced expression of amyloid precursor protein, presenilin-1 and rab3a in cortical brain regions in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2001;12(4):243-50.
2001: Jonathan A Prince; Lars Feuk; Sarah L Sawyer; Johan Gottfries; Anne Ricksten; Katarina Nägga; Nenad Bogdanovic; Kaj Blennow; Anthony J Brookes
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.
European journal of human genetics : EJHG 2001;9(6):437-44.
2001: Kaj Blennow; B Lind; E Andersson; Niels Andreasen
[CSF-analyses in clinical diagnosis of Creutzfeldt-Jakob disease. A literature review and three cases from routine clinical practice].
Läkartidningen 2001;98(20):2446-51.
2001: M Eriksson; Ulf Berggren; Kaj Blennow; Claudia Fahlke; Jan Balldin
Further investigation of citalopram on alcohol consumption in heavy drinkers: responsiveness possibly linked to the DRD2 A2/A2 genotype.
Alcohol (Fayetteville, N.Y.) 2001;24(1):15-23.
2001: C Hesse; Carol L Nilsson; Kaj Blennow; Pia Davidsson
Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry.
Electrophoresis 2001;22(9):1834-7.
2001: Magnus Sjögren; Pia Davidsson; Mats Tullberg; Lennart Minthon; Anders Wallin; Carsten Wikkelso; Ann-Kathrine Granérus; hugo vanderstichele; Eugeen Vanmechelen; Kaj Blennow
Both total and phosphorylated tau are increased in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2001;70(5):624-30.
2001: S F Fabre; Charlotte Forsell; Matti Viitanen; M Sjögren; Anders Wallin; Kaj Blennow; M Blomberg; C Andersen; Lars-Olof Wahlund; Lars Lannfelt
Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations.
Experimental neurology 2001;168(2):413-8.
2001: Pia Davidsson; Kaj Blennow; Niels Andreasen; B Eriksson; Lennart Minthon; C Hesse
Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease.
Neuroscience letters 2001;300(3):157-60.
2001: Pia Davidsson; Linda Paulson; C Hesse; Kaj Blennow; Carol L Nilsson
Proteome studies of human cerebrospinal fluid and brain tissue using a preparative two-dimensional electrophoresis approach prior to mass spectrometry.
Proteomics 2001;1(3):444-52.
2001: Niels Andreasen; Lennart Minthon; Pia Davidsson; Eugeen Vanmechelen; hugo vanderstichele; Bengt Winblad; Kaj Blennow
Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice.
Archives of neurology 2001;58(3):373-9.
2001: Elisabeth Tarkowski; Anders Wallin; Björn Regland; Kaj Blennow; Andrej Tarkowski
Local and systemic GM-CSF increase in Alzheimer's disease and vascular dementia.
Acta neurologica Scandinavica 2001;103(3):166-74.
2001: C Hesse; L Rosengren; Niels Andreasen; Pia Davidsson; hugo vanderstichele; Eugeen Vanmechelen; Kaj Blennow
Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke.
Neuroscience letters 2001;297(3):187-90.
2001: Johan Gottfries; Kaj Blennow; M W Lehmann; Björn Regland; Carl-Gerhard Gottfries
One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis.
Journal of geriatric psychiatry and neurology 2001;14(3):109-14.
2001: Henrik Soderstrom; Kaj Blennow; A Manhem; Anders Forsman
CSF studies in violent offenders. II. Blood-brain barrier dysfunction without concurrent inflammation or structure degeneration.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(7):879-86.
2001: Henrik Soderstrom; Kaj Blennow; A Manhem; Anders Forsman
CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(7):869-78.
2001: Magnus Sjögren; C Hesse; Hans Basun; G Köl; H Thostrup; Lena Kilander; Jan Marcusson; Ake Edman; Anders Wallin; Ingvar Karlsson; M Troell; G Wachtmaister; A Ekdahl; Hasse Olofsson; A Sandström; Niels Andreasen; Lennart Minthon; Kaj Blennow
Tacrine and rate of progression in Alzheimer's disease--relation to ApoE allele genotype.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(4):451-8.
2001: B Robertsson; Kaj Blennow; Görel Bråne; Ake Edman; Ingvar Karlsson; Anders Wallin; Carl-Gerhard Gottfries
Hyperactivity in the hypothalamic-pituitary-adrenal axis in demented patients with delirium.
International clinical psychopharmacology 2001;16(1):39-47.
2001: Jonathan A Prince; Lars Feuk; W Mathias Howell; Magnus Jobs; T Emahazion; Kaj Blennow; Anthony J Brookes
Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation.
Genome research 2001;11(1):152-62.
2001: V Chamoun; A Zeman; Kaj Blennow; P Fredman; Anders Wallin; Geoff Keir; Gavin Giovannoni; Edward J Thompson
Haptoglobins as markers of blood-CSF barrier dysfunction: the findings in normal CSF.
Journal of the neurological sciences 2001;182(2):117-21.
2000: hugo vanderstichele; E Van Kerschaver; C Hesse; Pia Davidsson; M A Buyse; Niels Andreasen; L Minthon; Anders Wallin; Kaj Blennow; Eugeen Vanmechelen
Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2000;7(4):245-58.
2000: C Hesse; L Rosengren; Eugeen Vanmechelen; hugo vanderstichele; C Jensen; Pia Davidsson; Kaj Blennow
Cerebrospinal fluid markers for Alzheimer's disease evaluated after acute ischemic stroke.
Journal of Alzheimer's disease : JAD 2000;2(3-4):199-206.
2000: Elisabeth Tarkowski; A Ringqvist; Kaj Blennow; Anders Wallin; Ake Wennmalm
Intrathecal release of nitric oxide in Alzheimer's disease and vascular dementia.
Dementia and geriatric cognitive disorders 2000;11(6):322-6.
2000: Olof Zachrisson; Jan Balldin; R Ekman; Ole Naesh; Lars Rosengren; Hans Agren; Kaj Blennow
No evident neuronal damage after electroconvulsive therapy.
Psychiatry research 2000;96(2):157-65.
2000: M Eriksson; Ulf Berggren; Kaj Blennow; Claudia Fahlke; J E Månsson; Jan Balldin
Alcoholics with the dopamine receptor DRD2 A1 allele have lower platelet monoamine oxidase-B activity than those with the A2 allele: a preliminary study.
Alcohol and alcoholism (Oxford, Oxfordshire) 2000;35(5):493-8.
2000: Mats Tullberg; Jan-Eric Månsson; Pam Fredman; Annika Lekman; Kaj Blennow; R Ekman; Lars Rosengren; Magnus Tisell; Carsten Wikkelsø
CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy.
Journal of neurology, neurosurgery, and psychiatry 2000;69(1):74-81.
2000: Elisabeth Tarkowski; Ann Marie Liljeroth; A Nilsson; Anne Ricksten; Pia Davidsson; Lennart Minthon; Kaj Blennow
TNF gene polymorphism and its relation to intracerebral production of TNFalpha and TNFbeta in AD.
Neurology 2000;54(11):2077-81.
2000: Eva Grundström; Dan Lindholm; A Johansson; Kaj Blennow; Håkan Askmark
GDNF but not BDNF is increased in cerebrospinal fluid in amyotrophic lateral sclerosis.
Neuroreport 2000;11(8):1781-3.
2000: Magnus Sjögren; Lars Rosengren; Lennart Minthon; Pia Davidsson; Kaj Blennow; Anders Wallin
Cytoskeleton proteins in CSF distinguish frontotemporal dementia from AD.
Neurology 2000;54(10):1960-4.
2000: Eugeen Vanmechelen; hugo vanderstichele; Pia Davidsson; E Van Kerschaver; B Van Der Perre; M Sjögren; Niels Andreasen; Kaj Blennow
Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization.
Neuroscience letters 2000;285(1):49-52.
2000: C Hesse; H Larsson; Pam Fredman; Lennart Minthon; Niels Andreasen; Pia Davidsson; Kaj Blennow
Measurement of apolipoprotein E (apoE) in cerebrospinal fluid.
Neurochemical research 2000;25(4):511-7.
2000: JA Prince; Jaanus Harro; Kaj Blennow; Carl-Gerhard Gottfries; Lars Oreland
Putamen mitochondrial energy metabolism is highly correlated to emotional and intellectual impairment in schizophrenics.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(3):284-92.
2000: Kaj Blennow; Lennart Minthon; Anders Wallin
[New discoveries on Alzheimer disease: new biochemical markers can hopefully improve diagnosis].
Läkartidningen 2000;97(1-2):6-10.
2000: Nenad Bogdanovic; P Davidsson; Inga Volkmann; Bengt Winblad; Kaj Blennow
Growth-associated protein GAP-43 in the frontal cortex and in the hippocampus in Alzheimer's disease: an immunohistochemical and quantitative study.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(4):463-78.
2000: Anders Wallin; Magnus Sjögren; Ake Edman; Kaj Blennow; Björn Regland
Symptoms, vascular risk factors and blood-brain barrier function in relation to CT white-matter changes in dementia.
European neurology 2000;44(4):229-35.
2000: M Sjögren; Lennart Minthon; Pia Davidsson; A Clarberg; hugo vanderstichele; Eugeen Vanmechelen; Anders Wallin; Kaj Blennow
CSF levels of tau, beta-amyloid(1-42) and GAP-43 in frontotemporal dementia, other types of dementia and normal aging.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(5):563-79.
2000: Kaj Blennow; N Bogdanovic; Markus Heilig; B Grenfeldt; Ingvar Karlsson; Pia Davidsson
Reduction of the synaptic protein rab3a in the thalamus and connecting brain regions in post-mortem schizophrenic brains.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(8-9):1085-97.
2000: Kaj Blennow; Anne Ricksten; Jonathan A Prince; Anthony J Brookes; T Emahazion; Carina Wasslavik; Nenad Bogdanovic; Niels Andreasen; Stellan Båtsman; Jan Marcusson; Katarina Nägga; Anders Wallin; Björn Regland; Hasse Olofsson; C Hesse; Pia Davidsson; Lennart Minthon; A Jansson; Lars Palmqvist; Lars Rymo
No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(8-9):1065-79.
1999: Mikael Landén; Pia Davidsson; Carl-Gerhard Gottfries; B Grenfeldt; Mats Stridsberg; Kaj Blennow
Reduction of the small synaptic vesicle protein synaptophysin but not the large dense core chromogranins in the left thalamus of subjects with schizophrenia.
Biological psychiatry 1999;46(12):1698-702.
1999: L Andersson; Kaj Blennow; Dietmar Fuchs; Bo Svennerholm; Magnus Gisslen
Increased cerebrospinal fluid protein tau concentration in neuro-AIDS.
Journal of the neurological sciences 1999;171(2):92-6.
1999: Pia Davidsson; Johan Gottfries; N Bogdanovic; R Ekman; Ingvar Karlsson; Carl-Gerhard Gottfries; Kaj Blennow
The synaptic-vesicle-specific proteins rab3a and synaptophysin are reduced in thalamus and related cortical brain regions in schizophrenic brains.
Schizophrenia research 1999;40(1):23-9.
1999: C Hesse; Nenad Bogdanovic; Pia Davidsson; Kaj Blennow
A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease.
Dementia and geriatric cognitive disorders 1999;10(6):452-9.
1999: Niels Andreasen; Lennart Minthon; A Clarberg; Pia Davidsson; Johan Gottfries; Eugeen Vanmechelen; hugo vanderstichele; Bengt Winblad; Kaj Blennow
Sensitivity, specificity, and stability of CSF-tau in AD in a community-based patient sample.
Neurology 1999;53(7):1488-94.
1999: Anders Wallin; Kaj Blennow; Lars Rosengren
Cerebrospinal fluid markers of pathogenetic processes in vascular dementia, with special reference to the subcortical subtype.
Alzheimer disease and associated disorders 1999;13 Suppl 3():S102-5.
1999: Niels Andreasen; Lennart Minthon; Eugeen Vanmechelen; hugo vanderstichele; Pia Davidsson; Bengt Winblad; Kaj Blennow
Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment.
Neuroscience letters 1999;273(1):5-8.
1999: Gunnar Engström; Christer Alling; Kaj Blennow; Göran Regnéll; Lil Träskman-Bendz
Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;9(5):399-405.
1999: JA Prince; Kaj Blennow; Carl-Gerhard Gottfries; Ingvar Karlsson; Lars Oreland
Mitochondrial function is differentially altered in the basal ganglia of chronic schizophrenics.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(3):372-9.
1999: Kaj Blennow; N Bogdanovic; Carl-Gerhard Gottfries; Pia Davidsson
The growth-associated protein GAP-43 is increased in the hippocampus and in the gyrus cinguli in schizophrenia.
Journal of molecular neuroscience : MN 1999;13(1-2):101-9.
1999: Elisabeth Tarkowski; Kaj Blennow; Anders Wallin; Andrej Tarkowski
Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia.
Journal of clinical immunology 1999;19(4):223-30.
1999: Björn Regland; Kaj Blennow; T Germgård; A C Koch-Schmidt; Carl-Gerhard Gottfries
The role of the polymorphic genes apolipoprotein E and methylene- tetrahydrofolate reductase in the development of dementia of the Alzheimer type.
Dementia and geriatric cognitive disorders 1999;10(4):245-51.
1999: Z Z Guan; X Zhang; Kaj Blennow; agneta nordberg
Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain.
Neuroreport 1999;10(8):1779-82.
1999: Mikael Landén; B Grenfeldt; Pia Davidsson; Mats Stridsberg; Björn Regland; Carl-Gerhard Gottfries; Kaj Blennow
Reduction of chromogranin A and B but not C in the cerebrospinal fluid in subjects with schizophrenia.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;9(4):311-5.
1999: Niels Andreasen; C Hesse; Pia Davidsson; Lennart Minthon; Anders Wallin; Bengt Winblad; hugo vanderstichele; Eugeen Vanmechelen; Kaj Blennow
Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.
Archives of neurology 1999;56(6):673-80.
1999: Frank Hulstaert; Kaj Blennow; Adrian Ivanoiu; H C Schoonderwaldt; Matthias Riemenschneider; P P De Deyn; C Bancher; Patrick cras; J Wiltfang; Pankaj D Mehta; Khalid Iqbal; Hans Pottel; Eugeen Vanmechelen; hugo vanderstichele
Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF.
Neurology 1999;52(8):1555-62.
1999: Carol L Nilsson; Maja Puchades; A Westman; Kaj Blennow; Pia Davidsson
Identification of proteins in a human pleural exudate using two-dimensional preparative liquid-phase electrophoresis and matrix-assisted laser desorption/ionization mass spectrometry.
Electrophoresis 1999;20(4-5):860-5.
1999: Lars Rosengren; Jan-Erik Karlsson; Magnus Sjögren; Kaj Blennow; Anders Wallin
Neurofilament protein levels in CSF are increased in dementia.
Neurology 1999;52(5):1090-3.
1999: Pia Davidsson; Maja Puchades; Kaj Blennow
Identification of synaptic vesicle, pre- and postsynaptic proteins in human cerebrospinal fluid using liquid-phase isoelectric focusing.
Electrophoresis 1999;20(3):431-7.
1999: Pia Davidsson; A Westman; Maja Puchades; Carol L Nilsson; Kaj Blennow
Characterization of proteins from human cerebrospinal fluid by a combination of preparative two-dimensional liquid-phase electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Analytical chemistry 1999;71(3):642-7.
1999: Maja Puchades; A Westman; Kaj Blennow; Pia Davidsson
Analysis of intact proteins from cerebrospinal fluid by matrix-assisted laser desorption/ionization mass spectrometry after two-dimensional liquid-phase electrophoresis.
Rapid communications in mass spectrometry : RCM 1999;13(24):2450-5.
1999: Maja Puchades; A Westman; Kaj Blennow; Pia Davidsson
Removal of sodium dodecyl sulfate from protein samples prior to matrix-assisted laser desorption/ionization mass spectrometry.
Rapid communications in mass spectrometry : RCM 1999;13(5):344-9.
1999: Niels Andreasen; Kaj Blennow; C Sjödin; Bengt Winblad; K Svärdsudd
Prevalence and incidence of clinically diagnosed memory impairments in a geographically defined general population in Sweden. The Piteå Dementia Project.
Neuroepidemiology 1999;18(3):144-55.
1998: Ingmar Skoog; J Marcusson; Kaj Blennow
Dementia. It's getting better all the time.
Lancet 1998;352 Suppl 4():SIV4.
1998: A M Lidström; Nenad Bogdanovic; C Hesse; Inga Volkman; Pia Davidsson; Kaj Blennow
Clusterin (apolipoprotein J) protein levels are increased in hippocampus and in frontal cortex in Alzheimer's disease.
Experimental neurology 1998;154(2):511-21.
1998: Magnus Sjögren; L Minthon; U Passant; Kaj Blennow; Anders Wallin
Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease.
Neurobiology of aging 1998;19(5):379-84.
1998: Ingmar Skoog; Anders Wallin; Pam Fredman; C Hesse; O Aevarsson; Ingvar Karlsson; Carl-Gerhard Gottfries; Kaj Blennow
A population study on blood-brain barrier function in 85-year-olds: relation to Alzheimer's disease and vascular dementia.
Neurology 1998;50(4):966-71.
1998: Pia Davidsson; Kaj Blennow
Neurochemical dissection of synaptic pathology in Alzheimer's disease.
International psychogeriatrics / IPA 1998;10(1):11-23.
1998: Niels Andreasen; Eugeen Vanmechelen; André Van de Voorde; Pia Davidsson; C Hesse; S Tarvonen; Ismo Räihä; Leif B Sourander; Bengt Winblad; Kaj Blennow
Cerebrospinal fluid tau protein as a biochemical marker for Alzheimer's disease: a community based follow up study.
Journal of neurology, neurosurgery, and psychiatry 1998;64(3):298-305.
1998: C Nilsson; A Westman; Kaj Blennow; Rolf Ekman
Processing of neuropeptide Y and somatostatin in human cerebrospinal fluid as monitored by radioimmunoassay and mass spectrometry.
Peptides 1998;19(7):1137-46.
1998: Kaj Blennow; Eugeen Vanmechelen
Combination of the different biological markers for increasing specificity of in vivo Alzheimer's testing.
Journal of neural transmission. Supplementum 1998;53():223-35.
1998: B Robertsson; Kaj Blennow; Carl-Gerhard Gottfries; Anders Wallin
Delirium in dementia.
International journal of geriatric psychiatry 1998;13(1):49-56.
1998: Ingmar Skoog; C Hesse; O Aevarsson; Sten Landahl; J Wahlström; Pam Fredman; Kaj Blennow
A population study of apoE genotype at the age of 85: relation to dementia, cerebrovascular disease, and mortality.
Journal of neurology, neurosurgery, and psychiatry 1998;64(1):37-43.
1997: Belén Arranz; Kaj Blennow; A Eriksson; J E Månsson; J Marcusson
Serotonergic, noradrenergic, and dopaminergic measures in suicide brains.
Biological psychiatry 1997;41(10):1000-9.
1997: S Tarvonen-Schröder; Kaj Blennow; Annika Lekman; Pam Fredman; Ismo Räihä; Leif B Sourander
Gangliosides and sulfatide in cerebrospinal fluid in leukoaraiosis.
Dementia and geriatric cognitive disorders 1997;8(3):174-9.
1997: Lennart Minthon; C Hesse; M Sjögren; E Englund; Lars Gustafson; Kaj Blennow
The apolipoprotein E epsilon4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease.
Neuroscience letters 1997;226(1):65-7.
1997: Ingmar Skoog; C Hesse; Pam Fredman; L A Andreasson; B Palmertz; Kaj Blennow
Apolipoprotein E in cerebrospinal fluid in 85-year-old subjects. Relation to dementia, apolipoprotein E polymorphism, cerebral atrophy, and white matter lesions.
Archives of neurology 1997;54(3):267-72.
1997: Pia Davidsson; R Ekman; Kaj Blennow
A new procedure for detecting brain-specific proteins in cerebrospinal fluid.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(6-7):711-20.
1997: LE Augustinsson; Kaj Blennow; Christian Blomstrand; Görel Bråne; R Ekman; Pam Fredman; Ingvar Karlsson; M Kihlgren; W Lehmann; Annika Lekman; Jan-Eric Månsson; I Ramström; Anders Wallin; Carsten Wikkelsö; Carl-Gerhard Gottfries; Lars Svennerholm
Intracerebroventricular administration of GM1 ganglioside to presenile Alzheimer patients.
Dementia and geriatric cognitive disorders 1997;8(1):26-33.
1996: Anders Wallin; Ake Edman; Kaj Blennow; Carl-Gerhard Gottfries; Ingvar Karlsson; Björn Regland; Magnus Sjögren
Stepwise comparative status analysis (STEP): a tool for identification of regional brain syndromes in dementia.
Journal of geriatric psychiatry and neurology 1996;9(4):185-99.
1996: Mikael Landén; A Thorsell; Anders Wallin; Kaj Blennow
The apolipoprotein E allele epsilon 4 does not correlate with the number of senile plaques or neurofibrillary tangles in patients with Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1996;61(4):352-6.
1996: Kaj Blennow; P Davidsson; Carl-Gerhard Gottfries; R Ekman; Markus Heilig
Synaptic degeneration in thalamus in schizophrenia.
Lancet 1996;348(9028):692-3.
1996: Mikael Landén; C Hesse; Pam Fredman; Björn Regland; Anders Wallin; Kaj Blennow
Apolipoprotein E in cerebrospinal fluid from patients with Alzheimer's disease and other forms of dementia is reduced but without any correlation to the apoE4 isoform.
Dementia (Basel, Switzerland) 1996;7(5):273-8.
1996: Anders Wallin; Kaj Blennow; Lars Rosengren
Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia.
Dementia (Basel, Switzerland) 1996;7(5):267-72.
1996: L Bayard-Burfield; Christer Alling; Kaj Blennow; SA Jönsson; Lil Träskman-Bendz
Impairment of the blood-CSF barrier in suicide attempters.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1996;6(3):195-9.
1996: U Strömbom; M Krotkiewski; Kaj Blennow; J E Månsson; R Ekman; P Björntorp
The concentrations of monoamine metabolites and neuropeptides in the cerebrospinal fluid of obese women with different body fat distribution.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1996;20(4):361-8.
1996: Markus Heilig; J E Månsson; Kaj Blennow
Cerebrospinal fluid monoamine metabolites and atmospheric pressure.
Biological psychiatry 1996;39(4):299-301.
1996: Pia Davidsson; R Jahn; J Bergquist; R Ekman; Kaj Blennow
Synaptotagmin, a synaptic vesicle protein, is present in human cerebrospinal fluid: a new biochemical marker for synaptic pathology in Alzheimer disease?
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1996;27(2):195-210.
1996: Anders Wallin; Kaj Blennow; A Edman; J E Månsson
Decreased lumbar cerebrospinal fluid levels of monoamine metabolites in vascular dementia.
International psychogeriatrics / IPA 1996;8(3):425-36.
1996: Belén Arranz; Kaj Blennow; R Ekman; A Eriksson; J E Månsson; Jan Marcusson
Brain monoaminergic and neuropeptidergic variations in human aging.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(1-2):101-15.
1996: Kaj Blennow; Richard Frank Cowburn
The neurochemistry of Alzheimer's disease.
Acta neurologica Scandinavica. Supplementum 1996;168():77-86.
1996: Kaj Blennow; Ingmar Skoog; Anders Wallin; Carsten Wikkelsö; P Fredman
Immunoglobulin M in cerebrospinal fluid: reference values derived from 111 healthy individuals 18-88 years of age.
European neurology 1996;36(4):201-5.
1996: Kaj Blennow; Nenad Bogdanovic; Irina Alafuzoff; R Ekman; Pia Davidsson
Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(5):603-18.
1996: Anders Wallin; Kaj Blennow
Clinical subgroups of the Alzheimer syndrome.
Acta neurologica Scandinavica. Supplementum 1996;165():51-7.
1996: C Nilsson; G Karlsson; Kaj Blennow; Markus Heilig; R Ekman
Differences in the neuropeptide Y-like immunoreactivity of the plasma and platelets of human volunteers and depressed patients.
Peptides 1996;17(3):359-62.
1995: Ingmar Skoog; Eugeen Vanmechelen; L A Andreasson; B Palmertz; Pia Davidsson; C Hesse; Kaj Blennow
A population-based study of tau protein and ubiquitin in cerebrospinal fluid in 85-year-olds: relation to severity of dementia and cerebral atrophy, but not to the apolipoprotein E4 allele.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(4):433-42.
1995: Kaj Blennow; Anders Wallin; Hans Agren; C Spenger; J Siegfried; Eugeen Vanmechelen
Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;26(3):231-45.
1995: Jan-Olof Karlsson; Kaj Blennow; I Janson; Klas Blomgren; Ingvar Karlsson; Björn Regland; Anders Wallin; Carl-Gerhard Gottfries
Increased proteolytic activity in lymphocytes from patients with early onset Alzheimer's disease.
Neurobiology of aging 1995;16(6):901-6.
1995: Kaj Blennow; Pia Davidsson; Anders Wallin; R Ekman
Chromogranin A in cerebrospinal fluid: a biochemical marker for synaptic degeneration in Alzheimer's disease?
Dementia (Basel, Switzerland) 1995;6(6):306-11.
1995: Markus Heilig; Magnus Sjögren; Kaj Blennow; R Ekman; Anders Wallin
Cerebrospinal fluid neuropeptides in Alzheimer's disease and vascular dementia.
Biological psychiatry 1995;38(4):210-6.
1995: Kaj Blennow; Anders Wallin; J K Chong
Cerebrospinal fluid 'neuronal thread protein' comes from serum by passage over the blood-brain barrier.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(2):187-93.
1995: Johan Gottfries; Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries
Diagnosis of dementias using partial least squares discriminant analysis.
Dementia (Basel, Switzerland) 1995;6(2):83-8.
1995: Kaj Blennow; Pam Fredman
Detection of cerebrospinal fluid leakage by isoelectric focusing on polyacrylamide gels with silver staining using the PhastSystem.
Acta neurochirurgica 1995;136(3-4):135-9.
1994: Kaj Blennow; C Hesse; P Fredman
Cerebrospinal fluid apolipoprotein E is reduced in Alzheimer's disease.
Neuroreport 1994;5(18):2534-6.
1994: E Josefsson; J E Månsson; Kaj Blennow; Andrej Tarkowski
Immunomodulating and anti-inflammatory properties of the sympatholytic compound 6-hydroxydopamine.
Journal of neuroimmunology 1994;55(2):161-9.
1994: Carl-Gerhard Gottfries; Jan Balldin; Kaj Blennow; G Bråne; Ingvar Karlsson; Björn Regland; Anders Wallin
Regulation of the hypothalamic-pituitary-adrenal axis in dementia disorders.
Annals of the New York Academy of Sciences 1994;746():336-43; discussion 343-4.
1994: Jan Balldin; Kaj Blennow; G Bråne; Carl-Gerhard Gottfries; Ingvar Karlsson; Björn Regland; Anders Wallin
Relationship between mental impairment and HPA axis activity in dementia disorders.
Dementia (Basel, Switzerland) 1994;5(5):252-6.
1994: Anders Wallin; Kaj Blennow
The clinical diagnosis of vascular dementia.
Dementia (Basel, Switzerland) 1994;5(3-4):181-4.
1994: Carl-Gerhard Gottfries; Kaj Blennow; Ingvar Karlsson; Anders Wallin
The neurochemistry of vascular dementia.
Dementia (Basel, Switzerland) 1994;5(3-4):163-7.
1994: K M Mattila; Tuula Pirttilä; Kaj Blennow; Anders Wallin; Matti Viitanen; H Frey
Altered blood-brain-barrier function in Alzheimer's disease?
Acta neurologica Scandinavica 1994;89(3):192-8.
1994: Kaj Blennow; P Fredman; Anders Wallin; Carl-Gerhard Gottfries; H Frey; T Pirttilä; Ingmar Skoog; Carsten Wikkelsö; L Svennerholm
Formulas for the quantitation of intrathecal IgG production. Their validity in the presence of blood-brain barrier damage and their utility in multiple sclerosis.
Journal of the neurological sciences 1994;121(1):90-6.
1994: Kaj Blennow; Pia Davidsson; Anders Wallin; Carl-Gerhard Gottfries; Lars Svennerholm
Ubiquitin in cerebrospinal fluid in Alzheimer's disease and vascular dementia.
International psychogeriatrics / IPA 1994;6(1):13-22; discussion 59-60.
1994: Carl-Gerhard Gottfries; Jan Balldin; Kaj Blennow; G Bråne; Ingvar Karlsson; Björn Regland; Anders Wallin
Hypothalamic dysfunction in dementia.
Journal of neural transmission. Supplementum 1994;43():203-9.
1994: Kaj Blennow; Anders Wallin; R Ekman
Neuron specific enolase in cerebrospinal fluid: a biochemical marker for neuronal degeneration in dementia disorders?
Journal of neural transmission. Parkinson's disease and dementia section 1994;8(3):183-91.
1993: Kaj Blennow; Anders Wallin; O Häger
Low frequency of post-lumbar puncture headache in demented patients.
Acta neurologica Scandinavica 1993;88(3):221-3.
1993: Anders Wallin; Kaj Blennow
Heterogeneity of vascular dementia: mechanisms and subgroups.
Journal of geriatric psychiatry and neurology 1993;6(3):177-88.
1993: Kerstin Landin; Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries
Low blood pressure and blood glucose levels in Alzheimer's disease. Evidence for a hypometabolic disorder?
Journal of internal medicine 1993;233(4):357-63.
1993: Anders Wallin; Kaj Blennow
[The concept of dementia--does it enlighten or confuse?].
Läkartidningen 1993;90(13):1235-6.
1993: Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries; Ingvar Karlsson; J E Månsson; Ingmar Skoog; Carsten Wikkelsö; Lars Svennerholm
Cerebrospinal fluid monoamine metabolites in 114 healthy individuals 18-88 years of age.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1993;3(1):55-61.
1993: Kaj Blennow; P Fredman; Anders Wallin; Carl-Gerhard Gottfries; Ingmar Skoog; Carsten Wikkelsö; Lars Svennerholm
Protein analysis in cerebrospinal fluid. III. Relation to blood-cerebrospinal fluid barrier function for formulas for quantitative determination of intrathecal IgG production.
European neurology 1993;33(2):134-42.
1993: Kaj Blennow; P Fredman; Anders Wallin; Carl-Gerhard Gottfries; Ingvar Karlsson; G Långström; Ingmar Skoog; Lars Svennerholm; Carsten Wikkelsö
Protein analysis in cerebrospinal fluid. II. Reference values derived from healthy individuals 18-88 years of age.
European neurology 1993;33(2):129-33.
1993: Kaj Blennow; P Fredman; Anders Wallin; Carl-Gerhard Gottfries; G Långström; Lars Svennerholm
Protein analyses in cerebrospinal fluid. I. Influence of concentration gradients for proteins on cerebrospinal fluid/serum albumin ratio.
European neurology 1993;33(2):126-8.
1993: Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries; J E Månsson; Lars Svennerholm
Concentration gradients for monoamine metabolites in lumbar cerebrospinal fluid.
Journal of neural transmission. Parkinson's disease and dementia section 1993;5(1):5-15.
1992: Kaj Blennow; Pia Davidsson; Anders Wallin; Pam Fredman; Carl-Gerhard Gottfries; Jan-Eric Månsson; Lars Svennerholm
Differences in cerebrospinal fluid gangliosides between "probable Alzheimer's disease" and normal aging.
Aging (Milan, Italy) 1992;4(4):301-6.
1992: Kaj Blennow; Anders Wallin
Clinical heterogeneity of probable Alzheimer's disease.
Journal of geriatric psychiatry and neurology 1992;5(2):106-13.
1992: Björn Regland; L Abrahamsson; Kaj Blennow; Carl-Gerhard Gottfries; Anders Wallin
Vitamin B12 in CSF: reduced CSF/serum B12 ratio in demented men.
Acta neurologica Scandinavica 1992;85(4):276-81.
1992: Pam Fredman; Anders Wallin; Kaj Blennow; Pia Davidsson; Carl-Gerhard Gottfries; Lars Svennerholm
Sulfatide as a biochemical marker in cerebrospinal fluid of patients with vascular dementia.
Acta neurologica Scandinavica 1992;85(2):103-6.
1992: Anders Wallin; Kaj Blennow
Clinical diagnosis of Alzheimer's disease by primary care physicians and specialists.
Acta neurologica Scandinavica. Supplementum 1992;139():26-31.
1992: Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries; Annika Lekman; Ingvar Karlsson; Ingmar Skoog; Lars Svennerholm
Significance of decreased lumbar CSF levels of HVA and 5-HIAA in Alzheimer's disease.
Neurobiology of aging 1992;13(1):107-13.
1991: Kaj Blennow; Pia Davidsson; Anders Wallin; Pam Fredman; Carl-Gerhard Gottfries; Ingvar Karlsson; Jan-Eric Månsson; Lars Svennerholm
Gangliosides in cerebrospinal fluid in 'probable Alzheimer's disease'.
Archives of neurology 1991;48(10):1032-5.
1991: R Prior; U Mönning; U Schreiter-Gasser; Andreas Weidemann; Kaj Blennow; Carl-Gerhard Gottfries; Colin L Masters; Konrad Beyreuther
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Neuroscience letters 1991;124(1):69-73.
1991: Kaj Blennow; Anders Wallin; C Uhlemann; Carl-Gerhard Gottfries
White-matter lesions on CT in Alzheimer patients: relation to clinical symptomatology and vascular factors.
Acta neurologica Scandinavica 1991;83(3):187-93.
1991: Anders Wallin; Kaj Blennow
Pathogenetic basis of vascular dementia.
Alzheimer disease and associated disorders 1991;5(2):91-102.
1990: Kaj Blennow; Anders Wallin; Carl-Gerhard Gottfries
Confusional symptomatology distinguishes early- and late-onset Alzheimer's disease.
Aging (Milan, Italy) 1990;2(4):395-401.
1990: Kaj Blennow; Anders Wallin; P Fredman; Carl-Gerhard Gottfries; Ingvar Karlsson; Lars Svennerholm
Intrathecal synthesis of immunoglobulins in patients with Alzheimer's disease.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1990;1(1):79-81.
1990: E Nilsson; Irina Alafuzoff; Kaj Blennow; Klas Blomgren; C M Hall; I Janson; Ingvar Karlsson; Anders Wallin; Carl-Gerhard Gottfries; Jan-Olof Karlsson
Calpain and calpastatin in normal and Alzheimer-degenerated human brain tissue.
Neurobiology of aging 1990;11(4):425-31.
1990: Kaj Blennow; Anders Wallin; Pam Fredman; Ingvar Karlsson; Carl-Gerhard Gottfries; Lars Svennerholm
Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors.
Acta neurologica Scandinavica 1990;81(4):323-6.
1990: Anders Wallin; Kaj Blennow; Pam Fredman; Carl-Gerhard Gottfries; Ingvar Karlsson; Lars Svennerholm
Blood brain barrier function in vascular dementia.
Acta neurologica Scandinavica 1990;81(4):318-22.
1990: Anders Wallin; Kaj Blennow; Pam Fredman; Carl-Gerhard Gottfries; Ingvar Karlsson; Lars Svennerholm
Intrathecal synthesis of immunoglobulin G in vascular dementia.
Acta neurologica Scandinavica 1990;81(2):168-72.
1990: Kaj Blennow; Anders Wallin; Pia Davidsson; P Fredman; Carl-Gerhard Gottfries; Lars Svennerholm
Intra-blood-brain-barrier synthesis of immunoglobulins in patients with dementia of the Alzheimer type.
Alzheimer disease and associated disorders 1990;4(2):79-86.
1990: Lars Svennerholm; Carl-Gerhard Gottfries; Kaj Blennow; Pam Fredman; Ingvar Karlsson; Jan-Eric Månsson; G Toffano; Anders Wallin
Parenteral administration of GM1 ganglioside to presenile Alzheimer patients.
Acta neurologica Scandinavica 1990;81(1):48-53.
1989: Anders Wallin; Kaj Blennow; C Uhlemann; G Långström; Carl-Gerhard Gottfries
White matter low attenuation on computed tomography in Alzheimer's disease and vascular dementia--diagnostic and pathogenetic aspects.
Acta neurologica Scandinavica 1989;80(6):518-23.
1989: G Bråne; Carl-Gerhard Gottfries; Kaj Blennow; Ingvar Karlsson; Annika Lekman; L Parnetti; Lars Svennerholm; Anders Wallin
Monoamine metabolites in cerebrospinal fluid and behavioral ratings in patients with early and late onset of Alzheimer dementia.
Alzheimer disease and associated disorders 1989;3(3):148-56.