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Jameel Shah

Research Profile

Chemicals & Drugs

Phenomena

Phosphorylation

Disorders

Tuberous Sclerosis

Physiology

Anatomy

Living Beings

Mouse
Rats

Co-author Network

Publications

TOP 3
Zhiyong Wang; O Jameel Shah; Tony Hunter
The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
O Jameel Shah; Xiaoyu Lin; Leiming Li; Xiaoli Huang; Junling Li; Mark G Anderson; Hua Tang; Luis E Rodriguez; Scott E Warder; Shaun McLoughlin; Jun Chen; Joann Palma; Keith B Glaser; Cherrie Donawho; Stephen W Fesik; Yu Shen
Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.
O Jameel Shah; Tony Hunter
Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.

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All Publications

2012: Zhiyong Wang; O Jameel Shah; Tony Hunter
The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
PloS one 2012;7(7):e36961.
2010: O Jameel Shah; Xiaoyu Lin; Leiming Li; Xiaoli Huang; Junling Li; Mark G Anderson; Hua Tang; Luis E Rodriguez; Scott E Warder; Shaun McLoughlin; Jun Chen; Joann Palma; Keith B Glaser; Cherrie Donawho; Stephen W Fesik; Yu Shen
Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(28):12634-9.
2006: O Jameel Shah; Tony Hunter
Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.
Molecular and cellular biology 2006;26(17):6425-34.
2005: O Jameel Shah; Tony Hunter
Tuberous sclerosis and insulin resistance. Unlikely bedfellows reveal a TORrid affair.
Cell cycle (Georgetown, Tex.) 2005;4(1):46-51.
2004: O Jameel Shah; Zhiyong Wang; Tony Hunter
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.
Current biology : CB 2004;14(18):1650-6.
2004: O Jameel Shah; Tony Hunter
Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex.
The Journal of biological chemistry 2004;279(20):20816-23.
2003: O Jameel Shah; Sourav Ghosh; Tony Hunter
Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2.
The Journal of biological chemistry 2003;278(18):16433-42.
2002: O Jameel Shah; Scot R Kimball; Leonard S Jefferson
The Src-family tyrosine kinase inhibitor PP1 interferes with the activation of ribosomal protein S6 kinases.
The Biochemical journal 2002;366(Pt 1):57-62.
2002: O Jameel Shah; Jorge A Iniguez-Lluhi; Angela Romanelli; Scot R Kimball; Leonard S Jefferson
The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K.
The Journal of biological chemistry 2002;277(4):2525-33.
2000: O Jameel Shah; Joshua C Anthony; Scot R Kimball; Leonard S Jefferson
Glucocorticoids oppose translational control by leucine in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2000;279(5):E1185-90.
2000: O Jameel Shah; Joshua C Anthony; Scot R Kimball; Leonard S Jefferson
4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle.
American journal of physiology. Endocrinology and metabolism 2000;279(4):E715-29.
2000: O Jameel Shah; Scot R Kimball; Leonard S Jefferson
Glucocorticoids abate p70(S6k) and eIF4E function in L6 skeletal myoblasts.
American journal of physiology. Endocrinology and metabolism 2000;279(1):E74-82.
2000: O Jameel Shah; Scot R Kimball; Leonard S Jefferson
Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids.
The Biochemical journal 2000;347(Pt 2):389-97.
2000: O Jameel Shah; Scot R Kimball; Leonard S Jefferson
Acute attenuation of translation initiation and protein synthesis by glucocorticoids in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2000;278(1):E76-82.
1999: O Jameel Shah; David Antonetti; Scot R Kimball; Leonard S Jefferson
Leucine, glutamine, and tyrosine reciprocally modulate the translation initiation factors eIF4F and eIF2B in perfused rat liver.
The Journal of biological chemistry 1999;274(51):36168-75.