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Stephen Shalet

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
27
Toogood, Andy
20
Rahim, Asad
20
Murray, Robert
19
Lissett, Catherine
18
Adams, Judith
17
Darzy, Ken
16
Renehan, Andrew
15
Brennan, Bernadette
15
Gleeson, Helena
14
Clayton, Peter
13
Robertson, WR
13
O'Dwyer, Sarah
12
Mukherjee, Annice
12
Gattamaneni, Rao
11
Howell, Simon

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Publications

TOP 3
Mukherjee A; Shalet S M
The value of IGF1 estimation in adults with GH deficiency.
Koltowska-Häggström Maria; Mattsson Anders F; Shalet Stephen M
Assessment of quality of life in adult patients with GH deficiency: KIMS contribution to clinical practice and pharmacoeconomic evaluations.
Jostel Andreas; Ryder W David J; Shalet Stephen M
The use of thyroid function tests in the diagnosis of hypopituitarism: definition and evaluation of the TSH Index.

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All Publications

2009: Mukherjee A; Shalet S M
The value of IGF1 estimation in adults with GH deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161 Suppl 1():S33-9.
2009: Koltowska-Häggström Maria; Mattsson Anders F; Shalet Stephen M
Assessment of quality of life in adult patients with GH deficiency: KIMS contribution to clinical practice and pharmacoeconomic evaluations.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161 Suppl 1():S51-64.
2009: Jostel Andreas; Ryder W David J; Shalet Stephen M
The use of thyroid function tests in the diagnosis of hypopituitarism: definition and evaluation of the TSH Index.
Clinical endocrinology 2009;71(4):529-34.
2009: Shalet Stephen M
Normal testicular function and spermatogenesis.
Pediatric blood & cancer 2009;53(2):285-8.
2009: Mukherjee A; Helbert M; Ryder W D J; Borrow R; Davis J R E; Shalet S M
Failure of antibody response to polysaccharide antigen in treated panhypopituitary adults.
Clinical and experimental immunology 2009;156(2):271-7.
2009: Berg C A; Pokrajac A; Bidlingmaier M; Strasburger C J; Shalet S M; Trainer P J
Use of a GH receptor antagonist (GHRA) to explore the relationship between GH and IGF-I in adults with severe GH deficiency (GHD).
Clinical endocrinology 2009;70(3):439-45.
2009: Columb Breeda; Smethurst Linda E; Mukherjee Annice; Jostel Andreas; Shalet Stephen M; Murray Robert D
GH sensitivity of GH-deficient adults is dependent on gender but not timing of onset.
Clinical endocrinology 2009;70(2):281-6.
2009: Darzy Ken H; Thorner Michael O; Shalet Stephen M
Cranially irradiated adult cancer survivors may have normal spontaneous GH secretion in the presence of discordant peak GH responses to stimulation tests (compensated GH deficiency).
Clinical endocrinology 2009;70(2):287-93.
2009: Gleeson Helena K; Shalet Stephen M
Effect of aromatizable and unaromatizable androgen replacement in hypogonadal men on GH responsiveness.
Clinical endocrinology 2009;70(1):109-15.
2009: Darzy Ken H; Shalet Stephen M
Hypopituitarism following Radiotherapy Revisited.
Endocrine development 2009;15():1-24.
2009: Darzy Ken H; Shalet Stephen M
Hypopituitarism following radiotherapy.
Pituitary 2009;12(1):40-50.
2008: Anderson Richard A; Weddell Annette; Spoudeas Helen A; Douglas Carolyn; Shalet Stephen M; Levitt Gill; Wallace W Hamish B
Do doctors discuss fertility issues before they treat young patients with cancer?
Human reproduction (Oxford, England) 2008;23(10):2246-51.
2008: Williams Allan J; Robson Helen; Kester Monique H A; van Leeuwen Johannes P T M; Shalet Stephen M; Visser Theo J; Williams Graham R
Iodothyronine deiodinase enzyme activities in bone.
Bone 2008;43(1):126-34.
2008: Karbownik-Lewinska Malgorzata; Kokoszko Agnieszka; Lewandowski Krzysztof C; Shalet Stephen M; Lewinski Andrzej
GH replacement reduces increased lipid peroxidation in GH-deficient adults.
Clinical endocrinology 2008;68(6):957-64.
2007: Clayton Peter; Gleeson Helena; Monson John; Popovic Vera; Shalet Stephen M; Christiansen J Sandahl
Growth hormone replacement throughout life: insights into age-related responses to treatment.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2007;17(5):369-82.
2007: Paisley Angela N; Rowles Susannah V; Roberts Margaret E; Webb Susan M; Badia X; Prieto L; Shalet Stephen M; Trainer Peter J
Treatment of acromegaly improves quality of life, measured by AcroQol.
Clinical endocrinology 2007;67(3):358-62.
2007: Renehan Andrew G; Frystyk Jan; Howell Anthony; O'dwyer Sarah T; Shalet Stephen M; Flyvbjerg Allan
The effects of sex steroid replacement therapy on an expanded panel of IGF-related peptides.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2007;17(3):210-9.
2007: Lemos Manuel C; Harding Brian; Shalet Stephen M; Thakker Rajesh V
A novel MEN1 intronic mutation associated with multiple endocrine neoplasia type 1.
Clinical endocrinology 2007;66(5):709-13.
2007: Cilliers Deirdre D; Parveen Rahat; Clayton Peter; Cairns Stephen A; Clarke Sheila; Shalet Stephen M; Black Graeme C M; Newman William G; Clayton-Smith Jill
A new X-linked mental retardation (XLMR) syndrome with late-onset primary testicular failure, short stature and microcephaly maps to Xq25-q26.
European journal of medical genetics 2007;50(3):216-23.
2007: Murray Robert D; Bidlingmaier Martin; Strasburger Christian J; Shalet Stephen M
The diagnosis of partial growth hormone deficiency in adults with a putative insult to the hypothalamo-pituitary axis.
The Journal of clinical endocrinology and metabolism 2007;92(5):1705-9.
2007: Darzy Ken H; Pezzoli Suzan S; Thorner Michael O; Shalet Stephen M
Cranial irradiation and growth hormone neurosecretory dysfunction: a critical appraisal.
The Journal of clinical endocrinology and metabolism 2007;92(5):1666-72.
2007: Attanasio Andrea F; Shalet Stephen M
Growth hormone and the transition from puberty into adulthood.
Endocrinology and metabolism clinics of North America 2007;36(1):187-201.
2007: McNay David E G; Turton James P; Kelberman Daniel; Woods Kathryn S; Brauner Raja; Papadimitriou Anastasios; Keller Eberhard; Keller Alexandra; Haufs Nele; Krude Heiko; Shalet Stephen M; Dattani Mehul T
HESX1 mutations are an uncommon cause of septooptic dysplasia and hypopituitarism.
The Journal of clinical endocrinology and metabolism 2007;92(2):691-7.
2007: Kaushal K; Shalet S M
Defining growth hormone status in adults with hypopituitarism.
Hormone research 2007;68(4):185-94.
2006: Darzy Ken H; Shalet Stephen M
Pathophysiology of radiation-induced growth hormone deficiency: efficacy and safety of GH replacement.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2006;16 Suppl A():S30-40.
2006: Mukherjee A; Ryder W D J; Jöstel A; Shalet S M
Prolactin deficiency is independently associated with reduced insulin-like growth factor I status in severely growth hormone-deficient adults.
The Journal of clinical endocrinology and metabolism 2006;91(7):2520-5.
2006: Molitch Mark E; Clemmons David R; Malozowski Saul; Merriam George R; Shalet Stephen M; Vance Mary Lee; Stephens Patricia A
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline.
The Journal of clinical endocrinology and metabolism 2006;91(5):1621-34.
2006: Woodhouse Linda J; Mukherjee Annice; Shalet Stephen M; Ezzat Shereen
The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults.
Endocrine reviews 2006;27(3):287-317.
2006: Darzy Ken H; Murray Robert D; Gleeson Helena K; Pezzoli Suzan S; Thorner Michael O; Shalet Stephen M
The impact of short-term fasting on the dynamics of 24-hour growth hormone (GH) secretion in patients with severe radiation-induced GH deficiency.
The Journal of clinical endocrinology and metabolism 2006;91(3):987-94.
2006: Murray Robert D; Adams Judith E; Shalet Stephen M
A densitometric and morphometric analysis of the skeleton in adults with varying degrees of growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 2006;91(2):432-8.
2006: Shalet Stephen
Adolescents with childhood-onset GHD: how do we get them to peak bone mass?
Hormone research 2006;65 Suppl 2():17-22.
2006: Jostel Andreas; Shalet Stephen M
Prospects for the development of long-acting formulations of human somatropin.
Treatments in endocrinology 2006;5(3):139-45.
2005: Gleeson Helena K; Shalet Stephen M
GH responsiveness varies during the menstrual cycle.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(6):775-9.
2005: Darzy Ken H; Shalet Stephen M
Circadian and stimulated thyrotropin secretion in cranially irradiated adult cancer survivors.
The Journal of clinical endocrinology and metabolism 2005;90(12):6490-7.
2005: Mukherjee Annice; Adams Judith E; Smethurst Linda; Shalet Stephen M
Interdependence of lean body mass and total body water, but not quality of life measures, during low dose GH replacement in GH-deficient adults.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(5):661-8.
2005: Darzy Ken H; Shalet Stephen M
Absence of adrenocorticotropin (ACTH) neurosecretory dysfunction but increased cortisol concentrations and production rates in ACTH-replete adult cancer survivors after cranial irradiation for nonpituitary brain tumors.
The Journal of clinical endocrinology and metabolism 2005;90(9):5217-25.
2005: Turton James P G; Reynaud Rachel; Mehta Ameeta; Torpiano John; Saveanu Alexandru; Woods Kathryn S; Tiulpakov Anatoly; Zdravkovic Vera; Hamilton Jill; Attard-Montalto Simon; Parascandalo Ray; Vella Cecil; Clayton Peter E; Shalet Stephen; Barton John; Brue Thierry; Dattani Mehul T
Novel mutations within the POU1F1 gene associated with variable combined pituitary hormone deficiency.
The Journal of clinical endocrinology and metabolism 2005;90(8):4762-70.
2005: Attanasio Andrea F; Shavrikova Elena P; Blum Werner F; Shalet Stephen M
Quality of life in childhood onset growth hormone-deficient patients in the transition phase from childhood to adulthood.
The Journal of clinical endocrinology and metabolism 2005;90(8):4525-9.
2005: Moore Christopher; Shalet Stephen; Manickam Kathiresan; Willard Terry; Maheshwari Hiralal; Baumann Gerhard
Voice abnormality in adults with congenital and adult-acquired growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 2005;90(7):4128-32.
2005: Renehan Andrew G; Egger Matthias; Minder Christoph; O'Dwyer Sarah T; Shalet Stephen M; Zwahlen Marcel
IGF-I, IGF binding protein-3 and breast cancer risk: comparison of 3 meta-analyses.
International journal of cancer. Journal international du cancer 2005;115(6):1006-7; author reply 1008.
2005: Jostel Andreas; Mukherjee Annice; Hulse Paul A; Shalet Stephen M
Adult growth hormone replacement therapy and neuroimaging surveillance in brain tumour survivors.
Clinical endocrinology 2005;62(6):698-705.
2005: Rowles Susannah V; Prieto L; Badia X; Shalet Steven M; Webb Susan M; Trainer Peter J
Quality of life (QOL) in patients with acromegaly is severely impaired: use of a novel measure of QOL: acromegaly quality of life questionnaire.
The Journal of clinical endocrinology and metabolism 2005;90(6):3337-41.
2005: Jostel Andreas; Mukherjee Annice; Alenfall Jan; Smethurst Linda; Shalet Stephen M
A new sustained-release preparation of human growth hormone and its pharmacokinetic, pharmacodynamic and safety profile.
Clinical endocrinology 2005;62(5):623-7.
2005: Darzy Ken H; Pezzoli Suzan S; Thorner Michael O; Shalet Stephen M
The dynamics of growth hormone (GH) secretion in adult cancer survivors with severe GH deficiency acquired after brain irradiation in childhood for nonpituitary brain tumors: evidence for preserved pulsatility and diurnal variation with increased secretory disorderliness.
The Journal of clinical endocrinology and metabolism 2005;90(5):2794-803.
2005: Renehan Andrew G; Shalet Stephen M
Diabetes, insulin therapy, and colorectal cancer.
BMJ (Clinical research ed.) 2005;330(7491):551-2.
2005: Renehan Andrew G; Painter John E; Bell G Duncan; Rowland Roger S; O'Dwyer Sarah T; Shalet Stephen M
Determination of large bowel length and loop complexity in patients with acromegaly undergoing screening colonoscopy.
Clinical endocrinology 2005;62(3):323-30.
2005: Mukherjee A; Tolhurst-Cleaver S; Ryder W D J; Smethurst L; Shalet S M
The characteristics of quality of life impairment in adult growth hormone (GH)-deficient survivors of cancer and their response to GH replacement therapy.
The Journal of clinical endocrinology and metabolism 2005;90(3):1542-9.
2005: Clayton P E; Cuneo R C; Juul A; Monson J P; Shalet S M; Tauber M;
Consensus statement on the management of the GH-treated adolescent in the transition to adult care.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(2):165-70.
2005: Murray Robert D; Shalet Stephen M
Insulin sensitivity is impaired in adults with varying degrees of GH deficiency.
Clinical endocrinology 2005;62(2):182-8.
2005: Brennan Bernadette M D; Mughal Zulf; Roberts Stephen A; Ward Kate; Shalet Stephen M; Eden Tim O B; Will Andrew M; Stevens Richard F; Adams Judith E
Bone mineral density in childhood survivors of acute lymphoblastic leukemia treated without cranial irradiation.
The Journal of clinical endocrinology and metabolism 2005;90(2):689-94.
2005: Gleeson Helena K; Lissett Catherine A; Shalet Stephen M
Insulin-like growth factor-I response to a single bolus of growth hormone is increased in obesity.
The Journal of clinical endocrinology and metabolism 2005;90(2):1061-7.
2005: Darzy Ken H; Shalet Stephen M
Hypopituitarism as a consequence of brain tumours and radiotherapy.
Pituitary 2005;8(3-4):203-11.
2005: Clayton Peter E; Shalet Stephen M
Difficulties in patient management associated with the transition period.
Hormone research 2005;64 Suppl 2():74-5.
2005: Darzy K H; Shalet S M
Hypopituitarism after cranial irradiation.
Journal of endocrinological investigation 2005;28(5 Suppl):78-87.
2005: Howell S J; Shalet S M
Spermatogenesis after cancer treatment: damage and recovery.
Journal of the National Cancer Institute. Monographs 2005;(34):12-7.
2004: Gleeson H K; Shalet S M
The impact of cancer therapy on the endocrine system in survivors of childhood brain tumours.
Endocrine-related cancer 2004;11(4):589-602.
2004: Attanasio Andrea F; Shavrikova Elena; Blum Werner F; Cromer Morris; Child Christopher J; Paskova Magdalena; Lebl Jan; Chipman John J; Shalet Stephen M;
Continued growth hormone (GH) treatment after final height is necessary to complete somatic development in childhood-onset GH-deficient patients.
The Journal of clinical endocrinology and metabolism 2004;89(10):4857-62.
2004: Renehan A G; Atkin W S; O'dwyer S T; Shalet S M
The effect of cigarette smoking use and cessation on serum insulin-like growth factors.
British journal of cancer 2004;91(8):1525-31.
2004: Eyden Brian; Radford John; Shalet Stephen M; Thomas Non; Brison Daniel R; Lieberman Brian A
Ultrastructural preservation of ovarian cortical tissue cryopreserved in dimethylsulfoxide for subsequent transplantation into young female cancer patients.
Ultrastructural pathology 2004;28(4):239-45.
2004: Shalet S M
Growth hormone outgrows growth.
Clinical endocrinology 2004;61(1):1-9.
2004: Randeva Harpal S; Lewandowski Krzysztof C; Komorowski Jan; Murray Robert D; O'Callaghan Chris J; Hillhouse Edward W; Stepien Henryk; Shalet Stephen M
Growth hormone replacement decreases plasma levels of matrix metalloproteinases (2 and 9) and vascular endothelial growth factor in growth hormone-deficient individuals.
Circulation 2004;109(20):2405-10.
2004: Renehan Andrew G; Zwahlen Marcel; Minder Christoph; O'Dwyer Sarah T; Shalet Stephen M; Egger Matthias
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis.
Lancet 2004;363(9418):1346-53.
2004: Murray Robert D; Adams Judith E; Shalet Stephen M
Adults with partial growth hormone deficiency have an adverse body composition.
The Journal of clinical endocrinology and metabolism 2004;89(4):1586-91.
2004: Mukherjee A; Murray R D; Teasdale G M; Shalet S M
Acquired prolactin deficiency (APD) after treatment for Cushing's disease is a reliable marker of irreversible severe GHD but does not reflect disease status.
Clinical endocrinology 2004;60(4):476-83.
2004: Murray Robert D; Columb Breeda; Adams Judith E; Shalet Stephen M
Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly.
The Journal of clinical endocrinology and metabolism 2004;89(3):1124-30.
2004: Gleeson Helena K; Gattamaneni H R; Smethurst Linda; Brennan Bernadette M; Shalet Stephen M
Reassessment of growth hormone status is required at final height in children treated with growth hormone replacement after radiation therapy.
The Journal of clinical endocrinology and metabolism 2004;89(2):662-6.
2004: Lissett Catherine A; Gleeson Helena; Shalet Stephen M
The insulin-like growth factor I generation test in adults.
Hormone research 2004;62 Suppl 1():44-9.
2004: Shalet S
Stepping into adulthood: the transition period.
Hormone research 2004;62 Suppl 4():15-22.
2004: Mukherjee Annice; Murray Robert D; Shalet Stephen M
Impact of growth hormone status on body composition and the skeleton.
Hormone research 2004;62 Suppl 3():35-41.
2003: Lissett Catherine A; Jönsson Peter; Monson John P; Shalet Stephen M;
Determinants of IGF-I status in a large cohort of growth hormone-deficient (GHD) subjects: the role of timing of onset of GHD.
Clinical endocrinology 2003;59(6):773-8.
2003: Mukherjee Annice; Murray Robert D; Columb Breeda; Gleeson Helena K; Shalet Stephen M
Acquired prolactin deficiency indicates severe hypopituitarism in patients with disease of the hypothalamic-pituitary axis.
Clinical endocrinology 2003;59(6):743-8.
2003: Mukherjee Annice; Monson John P; Jönsson Peter J; Trainer Peter J; Shalet Stephen M;
Seeking the optimal target range for insulin-like growth factor I during the treatment of adult growth hormone disorders.
The Journal of clinical endocrinology and metabolism 2003;88(12):5865-70.
2003: Renehan Andrew G; Jones Jenny; O'Dwyer Sarah T; Shalet Stephen M
Determination of IGF-I, IGF-II, IGFBP-2, and IGFBP-3 levels in serum and plasma: comparisons using the Bland-Altman method.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2003;13(6):341-6.
2003: Renehan A G; O'Connell J; O'Halloran D; Shanahan F; Potten C S; O'Dwyer S T; Shalet S M
Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(11-12):712-25.
2003: Lewandowski Krzysztof C; Murray Robert D; Drzewoski J; O'Callaghan Chris J; Czupryniak L; Hillhouse Edward W; Shalet Stephen M; Randeva Harpal S
Plasma total homocysteine concentrations in adults with growth hormone (GH) deficiency: effects of GH replacement.
Molecular genetics and metabolism 2003;80(3):330-7.
2003: Clemmons David R; Chihara Kazuo; Freda Pamela U; Ho Ken K Y; Klibanski Anne; Melmed Shlomo; Shalet Stephen M; Strasburger Christian J; Trainer Peter J; Thorner Michael O
Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm.
The Journal of clinical endocrinology and metabolism 2003;88(10):4759-67.
2003: Lissett Catherine A; Shalet Stephen M
The impact of dose and route of estrogen administration on the somatotropic axis in normal women.
The Journal of clinical endocrinology and metabolism 2003;88(10):4668-72.
2003: Abdul Shakoor S K; Shalet S M
Effects of GH replacement on metabolism and physical performance in GH deficient adults.
Journal of endocrinological investigation 2003;26(9):911-8.
2003: Shalet Stephen M; Shavrikova Elena; Cromer Morris; Child Christopher J; Keller Eberhard; Zapletalová Jirina; Moshang Thomas; Blum Werner F; Chipman John J; Quigley Charmian A; Attanasio Andrea F
Effect of growth hormone (GH) treatment on bone in postpubertal GH-deficient patients: a 2-year randomized, controlled, dose-ranging study.
The Journal of clinical endocrinology and metabolism 2003;88(9):4124-9.
2003: Mukherjee Annice; Shalet Stephen M
Growth hormone replacement therapy (GHRT) in children and adolescents: skeletal impact.
Medical and pediatric oncology 2003;41(3):235-42.
2003: Gleeson Helena K; Stoeter Rachel; Ogilvy-Stuart Amanda L; Gattamaneni H R; Brennan Bernadette M; Shalet Stephen M
Improvements in final height over 25 years in growth hormone (GH)-deficient childhood survivors of brain tumors receiving GH replacement.
The Journal of clinical endocrinology and metabolism 2003;88(8):3682-9.
2003: Mukherjee Annice; Attanasio Andrea F; Shalet Stephen M
Skeletal requirements for optimal growth hormone replacement in the transitional years.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2003;13 Suppl A():S130-5.
2003: Lissett Catherine A; Shalet Stephen M
The insulin-like growth factor-I generation test: peripheral responsiveness to growth hormone is not decreased with ageing.
Clinical endocrinology 2003;58(2):238-45.
2003: Carakushansky Mauri; Whatmore Andrew J; Clayton Peter E; Shalet Stephen M; Gleeson Helena K; Price David A; Levine Michael A; Salvatori Roberto
A new missense mutation in the growth hormone-releasing hormone receptor gene in familial isolated GH deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(1):25-30.
2003: Darzy K H; Aimaretti G; Wieringa G; Gattamaneni H Rao; Ghigo E; Shalet S M
The usefulness of the combined growth hormone (GH)-releasing hormone and arginine stimulation test in the diagnosis of radiation-induced GH deficiency is dependent on the post-irradiation time interval.
The Journal of clinical endocrinology and metabolism 2003;88(1):95-102.
2003: Darzy K H; Shalet S M
Radiation-induced growth hormone deficiency.
Hormone research 2003;59 Suppl 1():1-11.
2002: Robson H; Meyer S; Shalet S M; Anderson E; Roberts S; Eden O B
Platinum agents in the treatment of osteosarcoma: efficacy of cisplatin vs. carboplatin in human osteosarcoma cell lines.
Medical and pediatric oncology 2002;39(6):573-80.
2002: Siebler T; Robson H; Shalet S M; Williams G R
Dexamethasone inhibits and thyroid hormone promotes differentiation of mouse chondrogenic ATDC5 cells.
Bone 2002;31(4):457-64.
2002: Murray R D; Shalet S M
Adult growth hormone replacement: lessons learned and future direction.
The Journal of clinical endocrinology and metabolism 2002;87(10):4427-8.
2002: Howell S J; Shalet S M
Effect of cancer therapy on pituitary-testicular axis.
International journal of andrology 2002;25(5):269-76.
2002: Gilchrist F J; Murray R D; Shalet S M
The effect of long-term untreated growth hormone deficiency (GHD) and 9 years of GH replacement on the quality of life (QoL) of GH-deficient adults.
Clinical endocrinology 2002;57(3):363-70.
2002: Howell Simon J; Shalet Stephen M
Fertility preservation and management of gonadal failure associated with lymphoma therapy.
Current oncology reports 2002;4(5):443-52.
2002: Robson Helen; Siebler Thomas; Shalet Stephen M; Williams Graham R
Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth.
Pediatric research 2002;52(2):137-47.
2002: Patel L; Cooper C D; Quinton N D; Butler G E; Gill M S; Jefferson I G; Kibirige M S; Price D A; Shalet S M; Wales J K H; Ross R J M; Clayton P E;
Serum leptin and leptin binding activity in children and adolescents with hypothalamic dysfunction.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15(7):963-71.
2002: Attanasio Andrea F; Howell Simon; Bates Peter C; Frewer Paul; Chipman John; Blum Werner F; Shalet Stephen M
Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: a comparison with adult onset GHD patients.
The Journal of clinical endocrinology and metabolism 2002;87(7):3368-72.
2002: Brennan Bernadette M D; Shalet Stephen M
Endocrine late effects after bone marrow transplant.
British journal of haematology 2002;118(1):58-66.
2002: Gleeson Helena K; Souza Anita H O; Gill Matthew S; Wieringa Gilbert E; Barretto Elenilde S de A; Barretto-Filho J A S; Shalet Stephen M; Aguiar-Oliveira Manuel H; Clayton Peter E
Lipid profiles in untreated severe congenital isolated growth hormone deficiency through the lifespan.
Clinical endocrinology 2002;57(1):89-95.
2002: Parkinson C; Renehan A G; Ryder W D J; O'Dwyer S T; Shalet S M; Trainer P J
Gender and age influence the relationship between serum GH and IGF-I in patients with acromegaly.
Clinical endocrinology 2002;57(1):59-64.
2002: Lissett C A; Murray R D; Shalet S M
Timing of onset of growth hormone deficiency is a major influence on insulin-like growth factor I status in adult life.
Clinical endocrinology 2002;57(1):35-40.
2002: Gleeson Helena K; Darzy Ken; Shalet Stephen M
Late endocrine, metabolic and skeletal sequelae following treatment of childhood cancer.
Best practice & research. Clinical endocrinology & metabolism 2002;16(2):335-48.
2002: Lissett Catherine A; Shalet Stephen M
Childhood-onset growth hormone (GH) deficiency in adult life.
Best practice & research. Clinical endocrinology & metabolism 2002;16(2):209-24.
2002: Murray R D; Wieringa G E; Lissett C A; Darzy K H; Smethurst L E; Shalet S M
Low-dose GH replacement improves the adverse lipid profile associated with the adult GH deficiency syndrome.
Clinical endocrinology 2002;56(4):525-32.
2002: Attanasio Andrea F; Howell Simon; Bates Peter C; Blum Werner F; Frewer Paul; Quigley Charmian; Shalet Stephen M
Confirmation of severe GH deficiency after final height in patients diagnosed as GH deficient during childhood.
Clinical endocrinology 2002;56(4):503-7.
2002: Renehan Andrew G; Shalet Stephen M
Acromegaly and colorectal cancer: risk assessment should be based on population-based studies.
The Journal of clinical endocrinology and metabolism 2002;87(4):1909; author reply 1909.
2002: Maheshwari Hiralal G; Pezzoli Suzan S; Rahim Asad; Shalet Stephen M; Thorner Michael O; Baumann Gerhard
Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance.
American journal of physiology. Endocrinology and metabolism 2002;282(4):E943-51.
2002: Murray R D; Adams J E; Smethurst L E; Shalet S M
Spinal irradiation impairs the osteo-anabolic effects of low-dose GH replacement in adults with childhood-onset GH deficiency.
Clinical endocrinology 2002;56(2):169-74.
2002: Randeva Harpal S; Murray Robert D; Lewandowski Krzysztof C; O'Callaghan Chris J; Horn Rudiger; O'Hare Paul; Brabant Georg; Hillhouse Edward W; Shalet Stephen M
Differential effects of GH replacement on the components of the leptin system in GH-deficient individuals.
The Journal of clinical endocrinology and metabolism 2002;87(2):798-804.
2002: Harvey Clare B; O'Shea Patrick J; Scott Anthea J; Robson Helen; Siebler Thomas; Shalet Stephen M; Samarut Jacques; Chassande Olivier; Williams Graham R
Molecular mechanisms of thyroid hormone effects on bone growth and function.
Molecular genetics and metabolism 2002;75(1):17-30.
2002: Siebler T; Robson H; Bromley M; Stevens D A; Shalet S M; Williams G R
Thyroid status affects number and localization of thyroid hormone receptor expressing mast cells in bone marrow.
Bone 2002;30(1):259-66.
2002: Murray R D; Darzy K H; Gleeson H K; Shalet S M
GH-deficient survivors of childhood cancer: GH replacement during adult life.
The Journal of clinical endocrinology and metabolism 2002;87(1):129-35.
2002: Shalet S M; Brennan B M D
Growth and growth hormone status after a bone marrow transplant.
Hormone research 2002;58 Suppl 1():86-90.
2002: Siebler T; Shalet S M; Robson H
Effects of chemotherapy on bone metabolism and skeletal growth.
Hormone research 2002;58 Suppl 1():80-5.
2002: Shalet Stephen M; Brennan Bernadette M D
Puberty in children with cancer.
Hormone research 2002;57 Suppl 2():39-42.
2002: Van den Berghe Greet; Shalet Stephen M
Critical illness as a model of hypothalamic ageing.
Novartis Foundation symposium 2002;242():205-15; discussion 216-21.
2001: Renehan A G; Odwyer S T; Shalet S M
Screening colonoscopy for acromegaly in perspective.
Clinical endocrinology 2001;55(6):731-3.
2001: Renehan A G; Toogood A A; Ryder W D; Jones J; Potten C S; O'Dwyer S T; Shalet S M
Paradoxical elevations in serum IGF-II and IGF binding protein-2 in acromegaly: insights into the regulation of these peptides.
Clinical endocrinology 2001;55(4):469-75.
2001: Howell S J; Radford J A; Adams J E; Smets E M; Warburton R; Shalet S M
Randomized placebo-controlled trial of testosterone replacement in men with mild Leydig cell insufficiency following cytotoxic chemotherapy.
Clinical endocrinology 2001;55(3):315-24.
2001: Lissett C A; Clayton P E; Shalet S M
The acute leptin response to GH.
The Journal of clinical endocrinology and metabolism 2001;86(9):4412-5.
2001: Gleeson H K; Shalet S M
Endocrine complications of neoplastic diseases in children and adolescents.
Current opinion in pediatrics 2001;13(4):346-51.
2001: Howell S J; Shalet S M
Testicular function following chemotherapy.
Human reproduction update 2001;7(4):363-9.
2001: Darzy K H; Shalet S M
Evolving therapeutic strategies for acromegaly.
Journal of endocrinological investigation 2001;24(6):468-71.
2001: Lissett C A; Saleem S; Rahim A; Brennan B M; Shalet S M
The impact of irradiation on growth hormone responsiveness to provocative agents is stimulus dependent: results in 161 individuals with radiation damage to the somatotropic axis.
The Journal of clinical endocrinology and metabolism 2001;86(2):663-8.
2001: Peacey S R; Toogood A A; Veldhuis J D; Thorner M O; Shalet S M
The relationship between 24-hour growth hormone secretion and insulin-like growth factor I in patients with successfully treated acromegaly: impact of surgery or radiotherapy.
The Journal of clinical endocrinology and metabolism 2001;86(1):259-66.
2001: Murray R D; Peacey S R; Rahim A; Toogood A A; Thorner M O; Shalet S M
The diagnosis of growth hormone deficiency (GHD) in successfully treated acromegalic patients.
Clinical endocrinology 2001;54(1):37-44.
2001: Renehan A G; Painter J E; Atkin W S; Potten C S; Shalet S M; O'Dwyer S T
High-risk colorectal adenomas and serum insulin-like growth factors.
The British journal of surgery 2001;88(1):107-13.
2001: Howell S; Shalet S
Testosterone deficiency and replacement.
Hormone research 2001;56 Suppl 1():86-92.
2001: Siebler T; Robson H; Shalet S M; Williams G R
Glucocorticoids, thyroid hormone and growth hormone interactions: implications for the growth plate.
Hormone research 2001;56 Suppl 1():7-12.
2000: Stevens D A; Hasserjian R P; Robson H; Siebler T; Shalet S M; Williams G R
Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(12):2431-42.
2000: Renehan A G; Jones J; Potten C S; Shalet S M; O'Dwyer S T
Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer.
British journal of cancer 2000;83(10):1344-50.
2000: Robson H; Siebler T; Stevens D A; Shalet S M; Williams G R
Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation.
Endocrinology 2000;141(10):3887-97.
2000: Renehan A G; Bhaskar P; Painter J E; O'Dwyer S T; Haboubi N; Varma J; Ball S G; Shalet S M
The prevalence and characteristics of colorectal neoplasia in acromegaly.
The Journal of clinical endocrinology and metabolism 2000;85(9):3417-24.
2000: Renehan A G; Painter J E; O'Halloran D; Atkin W S; Potten C S; O'Dwyer S T; Shalet S M
Circulating insulin-like growth factor II and colorectal adenomas.
The Journal of clinical endocrinology and metabolism 2000;85(9):3402-8.
2000: Shalet S M
GH deficiency in the elderly: the case for GH replacement.
Clinical endocrinology 2000;53(3):279-80.
2000: Howell S J; Radford J A; Adams J E; Shalet S M
The impact of mild Leydig cell dysfunction following cytotoxic chemotherapy on bone mineral density (BMD) and body composition.
Clinical endocrinology 2000;52(5):609-16.
2000: Murray R D; Howell S J; Lissett C A; Shalet S M
Pre-treatment IGF-I level is the major determinant of GH dosage in adult GH deficiency.
Clinical endocrinology 2000;52(5):537-42.
2000: Shalet S M
Growth hormone (GH) replacement therapy: cancer in children receiving GH.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10 Suppl A():S49.
2000: Lissett C A; Shalet S M
Effects of growth hormone on bone and muscle.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10 Suppl B():S95-101.
2000: Toogood A A; Taylor N F; Shalet S M; Monson J P
Modulation of cortisol metabolism by low-dose growth hormone replacement in elderly hypopituitary patients.
The Journal of clinical endocrinology and metabolism 2000;85(4):1727-30.
2000: Wieringa G; Toogood A A; Ryder W D; Anderson J M; Mackness M; Shalet S M
Changes in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10(1):14-9.
2000: Howell S J; Radford J A; Smets E M; Shalet S M
Fatigue, sexual function and mood following treatment for haematological malignancy: the impact of mild Leydig cell dysfunction.
British journal of cancer 2000;82(4):789-93.
2000: Toogood A A; Taylor N F; Shalet S M; Monson J P
Sexual dimorphism of cortisol metabolism is maintained in elderly subjects and is not oestrogen dependent.
Clinical endocrinology 2000;52(1):61-6.
2000: Lissett C A; Shalet S M
Management of pituitary tumours: strategy for investigation and follow-up.
Hormone research 2000;53 Suppl 3():65-70.
2000: Howell S J; Wilton P; Lindberg A; Shalet S M
Growth hormone and neurofibromatosis.
Hormone research 2000;53 Suppl 1():70-6.
1999: Murray R D; Brennan B M; Rahim A; Shalet S M
Survivors of childhood cancer: long-term endocrine and metabolic problems dwarf the growth disturbance.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1999;88(433):5-12.
1999: Murray R D; Skillicorn C J; Howell S J; Lissett C A; Rahim A; Smethurst L E; Shalet S M
Influences on quality of life in GH deficient adults and their effect on response to treatment.
Clinical endocrinology 1999;51(5):565-73.
1999: Lissett C A; Thompson E G; Rahim A; Brennan B M; Shalet S M
How many tests are required to diagnose growth hormone (GH) deficiency in adults?
Clinical endocrinology 1999;51(5):551-7.
1999: Howell S J; Shalet S M
Aetiology-specific effect of premature ovarian failure on bone mass - is residual ovarian function important?
Clinical endocrinology 1999;51(5):531-4.
1999: Aguiar-Oliveira M H; Gill M S; de A Barretto E S; Alcântara M R; Miraki-Moud F; Menezes C A; Souza A H; Martinelli C E; Pereira F A; Salvatori R; Levine M A; Shalet S M; Camacho-Hubner C; Clayton P E
Effect of severe growth hormone (GH) deficiency due to a mutation in the GH-releasing hormone receptor on insulin-like growth factors (IGFs), IGF-binding proteins, and ternary complex formation throughout life.
The Journal of clinical endocrinology and metabolism 1999;84(11):4118-26.
1999: Hughes N R; Lissett C A; Shalet S M
Growth hormone status following treatment for Cushing's syndrome.
Clinical endocrinology 1999;51(1):61-6.
1999: Quinton N D; Smith R F; Clayton P E; Gill M S; Shalet S; Justice S K; Simon S A; Walters S; Postel-Vinay M C; Blakemore A I; Ross R J
Leptin binding activity changes with age: the link between leptin and puberty.
The Journal of clinical endocrinology and metabolism 1999;84(7):2336-41.
1999: Howell S J; Shalet S M
Pharmacological protection of the gonads.
Medical and pediatric oncology 1999;33(1):41-5.
1999: Murray R D; Skillicorn C J; Howell S J; Lissett C A; Rahim A; Shalet S M
Dose titration and patient selection increases the efficacy of GH replacement in severely GH deficient adults.
Clinical endocrinology 1999;50(6):749-57.
1999: Howell S J; Radford J A; Ryder W D; Shalet S M
Testicular function after cytotoxic chemotherapy: evidence of Leydig cell insufficiency.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(5):1493-8.
1999: Brennan B M; Rahim A; Adams J A; Eden O B; Shalet S M
Reduced bone mineral density in young adults following cure of acute lymphoblastic leukaemia in childhood.
British journal of cancer 1999;79(11-12):1859-63.
1999: Gill M S; Toogood A A; Jones J; Clayton P E; Shalet S M
Serum leptin response to the acute and chronic administration of growth hormone (GH) to elderly subjects with GH deficiency.
The Journal of clinical endocrinology and metabolism 1999;84(4):1288-95.
1999: Maheshwari H G; Rahim A; Shalet S M; Baumann G
Selective lack of growth hormone (GH) response to the GH-releasing peptide hexarelin in patients with GH-releasing hormone receptor deficiency.
The Journal of clinical endocrinology and metabolism 1999;84(3):956-9.
1999: Brennan B M; Rahim A; Blum W F; Adams J A; Eden O B; Shalet S M
Hyperleptinaemia in young adults following cranial irradiation in childhood: growth hormone deficiency or leptin insensitivity?
Clinical endocrinology 1999;50(2):163-9.
1999: Rahim A; O'Neill P A; Shalet S M
The effect of chronic hexarelin administration on the pituitary-adrenal axis and prolactin.
Clinical endocrinology 1999;50(1):77-84.
1999: Bassett J H; O'Halloran D J; Williams G R; Beardwell C G; Shalet S M; Thakker R V
Novel DAX1 mutations in X-linked adrenal hypoplasia congenita and hypogonadotrophic hypogonadism.
Clinical endocrinology 1999;50(1):69-75.
1999: Toogood A A; Shalet S M
Growth hormone replacement therapy in the elderly with hypothalamic-pituitary disease: a dose-finding study.
The Journal of clinical endocrinology and metabolism 1999;84(1):131-6.
1999: Murray R D; Shalet S M
The use of self-rating questionnaires as a quantitative measure of quality of life in adult growth hormone deficiency.
Journal of endocrinological investigation 1999;22(5 Suppl):118-26.
1998: Howell S; Shalet S
Gonadal damage from chemotherapy and radiotherapy.
Endocrinology and metabolism clinics of North America 1998;27(4):927-43.
1998: Rahim A; O'Neill P; Shalet S M
The effect of body composition on hexarelin-induced growth hormone release in normal elderly subjects.
Clinical endocrinology 1998;49(5):659-64.
1998: Lissett C A; Peacey S R; Laing I; Tetlow L; Davis J R; Shalet S M
The outcome of surgery for acromegaly: the need for a specialist pituitary surgeon for all types of growth hormone (GH) secreting adenoma.
Clinical endocrinology 1998;49(5):653-7.
1998: Howell S J; Berger G; Adams J E; Shalet S M
Bone mineral density in women with cytotoxic-induced ovarian failure.
Clinical endocrinology 1998;49(3):397-402.
1998: Howell S J; Wilton P; Lindberg A; Shalet S M
Growth hormone replacement and the risk of malignancy in children with neurofibromatosis.
The Journal of pediatrics 1998;133(2):201-5.
1998: Toogood A A; Shalet S M
Ageing and growth hormone status.
Baillière's clinical endocrinology and metabolism 1998;12(2):281-96.
1998: Curran A J; Peacey S R; Shalet S M
Is maternal growth hormone essential for a normal pregnancy?
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(1):54-8.
1998: Gill M S; Toogood A A; O'Neill P A; Thorner M O; Shalet S M; Clayton P E
Urinary growth hormone (GH), insulin-like growth factor I (IGF-I), and IGF-binding protein-3 measurements in the diagnosis of adult GH deficiency.
The Journal of clinical endocrinology and metabolism 1998;83(7):2562-5.
1998: Brennan B M; Rahim A; Mackie E M; Eden O B; Shalet S M
Growth hormone status in adults treated for acute lymphoblastic leukaemia in childhood.
Clinical endocrinology 1998;48(6):777-83.
1998: Toogood A A; Jones J; O'Neill P A; Thorner M O; Shalet S M
The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic-pituitary disease.
Clinical endocrinology 1998;48(5):569-76.
1998: Robson H; Anderson E; Eden O B; Isaksson O; Shalet S
Chemotherapeutic agents used in the treatment of childhood malignancies have direct effects on growth plate chondrocyte proliferation.
The Journal of endocrinology 1998;157(2):225-35.
1998: Howell S J; Wilton P; Shalet S M
Growth hormone replacement in patients with Langerhan's cell histiocytosis.
Archives of disease in childhood 1998;78(5):469-73.
1998: Peacey S R; Toogood A A; Shalet S M
Hypothalamic dysfunction in "cured" acromegaly is treatment modality dependent.
The Journal of clinical endocrinology and metabolism 1998;83(5):1682-6.
1998: Rahim A; O'Neill P A; Shalet S M
Growth hormone status during long-term hexarelin therapy.
The Journal of clinical endocrinology and metabolism 1998;83(5):1644-9.
1998: Shalet S M; Rosenfeld R G
Growth hormone replacement therapy during transition of patients with childhood-onset growth hormone deficiency into adulthood: what are the issues?
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():177-84.
1998: Rahim A; Shalet S M
Does desensitization to hexarelin occur?
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():141-3.
1998: Rahim A; Holmes S J; Adams J E; Shalet S M
Long-term change in the bone mineral density of adults with adult onset growth hormone (GH) deficiency in response to short or long-term GH replacement therapy.
Clinical endocrinology 1998;48(4):463-9.
1998: Shalet S M; Toogood A; Rahim A; Brennan B M
The diagnosis of growth hormone deficiency in children and adults.
Endocrine reviews 1998;19(2):203-23.
1998: Toogood A A; Shalet S M
Conflicts with the somatopause.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl A():47-54.
1998: Lissett C A; Toogood A A; Didi M; Shalet S M
Growth hormone replacement in an adult with mild growth hormone deficiency and hereditary motor and sensory neuropathy: growth hormone restores independent mobility.
Hormone research 1998;50(4):232-6.
1998: Tillmann V; Shalet S M; Price D A; Wales J K; Pennells L; Soden J; Gill M S; Whatmore A J; Clayton P E
Serum insulin-like growth factor-I, IGF binding protein-3 and IGFBP-3 protease activity after cranial irradiation.
Hormone research 1998;50(2):71-7.
1998: Shalet S M; Brennan B M
Growth and growth hormone status following treatment for childhood leukaemia.
Hormone research 1998;50(1):1-10.
1998: Robson H; Anderson E; Eden O; Isaksson O; Shalet S
Glucocorticoid pretreatment reduces the cytotoxic effects of a variety of DNA-damaging agents on rat tibial growth-plate chondrocytes in vitro.
Cancer chemotherapy and pharmacology 1998;42(2):171-6.
1997: Toogood A A; Shalet S M
Diagnosis of severe growth hormone (GH) deficiency in young adults who received GH replacement therapy during childhood.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1997;423():117-20.
1997: Gill M S; Toogood A A; O'Neill P A; Adams J E; Thorner M O; Shalet S M; Clayton P E
Relationship between growth hormone (GH) status, serum leptin and body composition in healthy and GH deficient elderly subjects.
Clinical endocrinology 1997;47(2):161-7.
1997: Toogood A A; Nass R M; Pezzoli S S; O'Neill P A; Thorner M O; Shalet S M
Preservation of growth hormone pulsatility despite pituitary pathology, surgery, and irradiation.
The Journal of clinical endocrinology and metabolism 1997;82(7):2215-21.
1997: Kiltie A E; Collins C D; Gattamaneni H R; Shalet S M
Relapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement.
Medical and pediatric oncology 1997;29(1):41-4.
1997: Ogilvy-Stuart A L; Stirling H F; Kelnar C J; Savage M O; Dunger D B; Buckler J M; Shalet S M
Treatment of radiation-induced growth hormone deficiency with growth hormone-releasing hormone.
Clinical endocrinology 1997;46(5):571-8.
1997: Toogood A A; Adams J E; O'Neill P A; Shalet S M
Elderly patients with adult-onset growth hormone deficiency are not osteopenic.
The Journal of clinical endocrinology and metabolism 1997;82(5):1462-6.
1997: Shalet S M
Cytotoxic endocrinopathy: a legacy of insults.
Journal of the Royal Society of Medicine 1997;90(4):192-9.
1997: Crowne E C; Wallace W H; Moore C; Mitchell R; Robertson W H; Holly J M; Shalet S M
Effect of low dose oxandrolone and testosterone treatment on the pituitary-testicular and GH axes in boys with constitutional delay of growth and puberty.
Clinical endocrinology 1997;46(2):209-16.
1997: Tillmann V; Buckler J M; Kibirige M S; Price D A; Shalet S M; Wales J K; Addison M G; Gill M S; Whatmore A J; Clayton P E
Biochemical tests in the diagnosis of childhood growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 1997;82(2):531-5.
1997: Shalet S M; Brennan B M; Reddingius R E
Growth hormone therapy and malignancy.
Hormone research 1997;48 Suppl 4():29-32.
1996: Rahim A; Toogood A A; Shalet S M
The assessment of growth hormone status in normal young adult males using a variety of provocative agents.
Clinical endocrinology 1996;45(5):557-62.
1996: Shalet S M; Rahim A; Toogood A A
Growth hormone therapy for adult growth hormone deficiency.
Trends in endocrinology and metabolism: TEM 1996;7(8):287-90.
1996: Toogood A A; Adams J E; O'Neill P A; Shalet S M
Body composition in growth hormone deficient adults over the age of 60 years.
Clinical endocrinology 1996;45(4):399-405.
1996: Shalet S M
Endocrine sequelae of cancer therapy.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(2):135-43.
1996: Mackie E J; Radford M; Shalet S M
Gonadal function following chemotherapy for childhood Hodgkin's disease.
Medical and pediatric oncology 1996;27(2):74-8.
1996: O'Halloran D J; Wieringa G; Tsatsoulis A; Shalet S M
Increased serum lipoprotein(a) concentrations after growth hormone (GH) treatment in patients with isolated GH deficiency.
Annals of clinical biochemistry 1996;33 ( Pt 4)():330-4.
1996: Nicolson A; Toogood A A; Rahim A; Shalet S M
The prevalence of severe growth hormone deficiency in adults who received growth hormone replacement in childhood [see comment]
Clinical endocrinology 1996;44(3):311-6.
1996: Holmes S J; Ironside J W; Shalet S M
Neurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood.
Journal of neurology, neurosurgery, and psychiatry 1996;60(3):333-5.
1996: Toogood A A; O'Neill P A; Shalet S M
Beyond the somatopause: growth hormone deficiency in adults over the age of 60 years.
The Journal of clinical endocrinology and metabolism 1996;81(2):460-5.
1996: O'Halloran D J; Shalet S M
Radiotherapy for pituitary adenomas: an endocrinologist's perspective.
Clinical oncology (Royal College of Radiologists (Great Britain)) 1996;8(2):79-84.
1996: Holmes S J; Shalet S M
Adult growth hormone deficiency and bone mass.
Hormone research 1996;45 Suppl 1():69-71.
1996: Holmes S J; Shalet S M
Role of growth hormone and sex steroids in achieving and maintaining normal bone mass.
Hormone research 1996;45(1-2):86-93.
1995: Toogood A A; Eng C; Smith D P; Ponder B A; Shalet S M
No mutation at codon 918 of the RET gene in a family with multiple endocrine neoplasia type 2B.
Clinical endocrinology 1995;43(6):759-62.
1995: Didcock E; Davies H A; Didi M; Ogilvy Stuart A L; Wales J K; Shalet S M
Pubertal growth in young adult survivors of childhood leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(10):2503-7.
1995: Davies H A; Didcock E; Didi M; Ogilvy-Stuart A; Wales J K; Shalet S M
Growth, puberty and obesity after treatment for leukaemia.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1995;411():45-50; discussion 51.
1995: O'Halloran D J; Shalet S M
Acromegaly: unravelling a complex disease.
Growth regulation 1995;5(3):119-24.
1995: Ogilvy-Stuart A L; Shalet S M
Growth and puberty after growth hormone treatment after irradiation for brain tumours.
Archives of disease in childhood 1995;73(2):141-6.
1995: Holmes S J; Shalet S M
Factors influencing the desire for long-term growth hormone replacement in adults.
Clinical endocrinology 1995;43(2):151-7.
1995: Holmes S J; Shalet S M
Which adults develop side-effects of growth hormone replacement?
Clinical endocrinology 1995;43(2):143-9.
1995: Toogood A A; Ryder W D; Beardwell C G; Shalet S M
The evolution of radiation-induced growth hormone deficiency in adults is determined by the baseline growth hormone status.
Clinical endocrinology 1995;43(1):97-103.
1995: Didi M; Didcock E; Davies H A; Ogilvy-Stuart A L; Wales J K; Shalet S M
High incidence of obesity in young adults after treatment of acute lymphoblastic leukemia in childhood.
The Journal of pediatrics 1995;127(1):63-7.
1995: Crowne E C; Wallace W H; Moore C; Mitchell R; Robertson W R; Shalet S M
Degree of activation of the pituitary-testicular axis in early pubertal boys with constitutional delay of growth and puberty determines the growth response to treatment with testosterone or oxandrolone.
The Journal of clinical endocrinology and metabolism 1995;80(6):1869-75.
1995: Holmes S J; Whitehouse R W; Swindell R; Economou G; Adams J E; Shalet S M
Effect of growth hormone replacement on bone mass in adults with adult onset growth hormone deficiency.
Clinical endocrinology 1995;42(6):627-33.
1995: Holmes S J; Shalet S M
Characteristics of adults who wish to enter a trial of growth hormone replacement.
Clinical endocrinology 1995;42(6):613-8.
1995: Shalet S M; Didi M; Ogilvy-Stuart A L; Schulga J; Donaldson M D
Growth and endocrine function after bone marrow transplantation.
Clinical endocrinology 1995;42(4):333-9.
1995: Holmes S J; Whitehouse R W; Economou G; O'Halloran D J; Adams J E; Shalet S M
Further increase in forearm cortical bone mineral content after discontinuation of growth hormone replacement.
Clinical endocrinology 1995;42(1):3-7.
1995: Clark S T; Radford J A; Crowther D; Swindell R; Shalet S M
Gonadal function following chemotherapy for Hodgkin's disease: a comparative study of MVPP and a seven-drug hybrid regimen.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(1):134-9.
1994: Toogood A A; Beardwell C G; Shalet S M
The severity of growth hormone deficiency in adults with pituitary disease is related to the degree of hypopituitarism.
Clinical endocrinology 1994;41(4):511-6.
1994: Holmes S J; Whitehouse R W; Clark S T; Crowther D C; Adams J E; Shalet S M
Reduced bone mineral density in men following chemotherapy for Hodgkin's disease.
British journal of cancer 1994;70(2):371-5.
1994: Ogilvy-Stuart A L; Wallace W H; Shalet S M
Radiation and neuroregulatory control of growth hormone secretion.
Clinical endocrinology 1994;41(2):163-8.
1994: Ogilvy-Stuart A L; Clayton P E; Shalet S M
Cranial irradiation and early puberty.
The Journal of clinical endocrinology and metabolism 1994;78(6):1282-6.
1994: Davies H A; Didcock E; Didi M; Ogilvy-Stuart A; Wales J K; Shalet S M
Disproportionate short stature after cranial irradiation and combination chemotherapy for leukaemia.
Archives of disease in childhood 1994;70(6):472-5.
1994: Holmes S J; Economou G; Whitehouse R W; Adams J E; Shalet S M
Reduced bone mineral density in patients with adult onset growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 1994;78(3):669-74.
1994: O'Halloran D J; Shalet S M
A family pedigree exhibiting features of both multiple endocrine neoplasia type 1 and McCune-Albright syndromes.
The Journal of clinical endocrinology and metabolism 1994;78(3):523-5.
1994: Didi M; Morris-Jones P H; Gattamaneni H R; Shalet S M
Pubertal growth in response to testosterone replacement therapy for radiation-induced Leydig cell failure.
Medical and pediatric oncology 1994;22(4):250-4.
1993: Crowne E C; Wallace W H; Gibson S; Moore C M; White A; Shalet S M
Adrenocorticotrophin and cortisol secretion in children after low dose cranial irradiation.
Clinical endocrinology 1993;39(3):297-305.
1993: Ogilvy-Stuart A L; Shalet S M
Effect of radiation on the human reproductive system.
Environmental health perspectives 1993;101 Suppl 2():109-16.
1993: Dobrashian R D; O'Halloran D J; Hunt A; Beardwell C G; Shalet S M
Relationships between insulin-like growth factor-1 levels and growth hormone concentrations during diurnal profiles and following oral glucose in acromegaly.
Clinical endocrinology 1993;38(6):589-93.
1993: O'Halloran D J; Tsatsoulis A; Whitehouse R W; Holmes S J; Adams J E; Shalet S M
Increased bone density after recombinant human growth hormone (GH) therapy in adults with isolated GH deficiency.
The Journal of clinical endocrinology and metabolism 1993;76(5):1344-8.
1993: Buckler H M; Critchley H O; Cantrill J A; Shalet S M; Anderson D C; Robertson W R
Efficacy of low dose purified FSH in ovulation induction following pituitary desensitization in polycystic ovarian syndrome.
Clinical endocrinology 1993;38(2):209-17.
1993: Wallace W H; Shalet S M; Tetlow L J; Morris-Jones P H
Ovarian function following the treatment of childhood acute lymphoblastic leukaemia.
Medical and pediatric oncology 1993;21(5):333-9.
1993: Anderson E; Ferguson J E; Morten H; Shalet S M; Robinson E L; Howell A
Serum immunoreactive and bioactive lactogenic hormones in advanced breast cancer patients treated with bromocriptine and octreotide.
European journal of cancer (Oxford, England : 1990) 1993;29A(2):209-17.
1993: Shalet S M
Effect of irradiation treatment on gonadal function in men treated for germ cell cancer.
European urology 1993;23(1):148-51; discussion 152.
1993: Razzaq R; O'Halloran D J; Beardwell C G; Shalet S M
The effects of CV205-502 in patients with hyperprolactinaemia intolerant and/or resistant to bromocriptine.
Hormone research 1993;39(5-6):218-22.
1992: Ogilvy-Stuart A L; Shalet S M
Growth hormone and puberty.
The Journal of endocrinology 1992;135(3):405-6.
1992: Ogilvy-Stuart A L; Clark D J; Wallace W H; Gibson B E; Stevens R F; Shalet S M; Donaldson M D
Endocrine deficit after fractionated total body irradiation.
Archives of disease in childhood 1992;67(9):1107-10.
1992: Shalet S M; Crowne E C; Didi M A; Ogilvy-Stuart A L; Wallace W H
Irradiation-induced growth failure.
Baillière's clinical endocrinology and metabolism 1992;6(3):513-26.
1992: Ogilvy-Stuart A L; Ryder W D; Gattamaneni H R; Clayton P E; Shalet S M
Growth hormone and tumour recurrence.
BMJ (Clinical research ed.) 1992;304(6842):1601-5.
1992: Crowne E C; Wallace W H; Shalet S M; Addison G M; Price D A
Relationship between urinary and serum growth hormone and pubertal status.
Archives of disease in childhood 1992;67(1):91-5.
1992: Crowne E C; Moore C; Wallace W H; Ogilvy-Stuart A L; Addison G M; Morris-Jones P H; Shalet S M
A novel variant of growth hormone (GH) insufficiency following low dose cranial irradiation.
Clinical endocrinology 1992;36(1):59-68.
1992: Ogilvy-Stuart A L; Shalet S M
Tumour occurrence and recurrence.
Hormone research 1992;38 Suppl 1():50-5.
1991: Littley M D; Shalet S M; Reid H; Beardwell C G; Sutton M L
The effect of external pituitary irradiation on elevated serum prolactin levels in patients with pituitary macroadenomas.
The Quarterly journal of medicine 1991;81(296):985-98.
1991: Ogilvy-Stuart A L; Shalet S M; Gattamaneni H R
Thyroid function after treatment of brain tumors in children.
The Journal of pediatrics 1991;119(5):733-7.
1991: Wallace W H; Shalet S M; Lendon M; Morris-Jones P H
Male fertility in long-term survivors of childhood acute lymphoblastic leukaemia.
International journal of andrology 1991;14(5):312-9.
1991: Tsatsoulis A; Shalet S M
Antisperm antibodies in the polyglandular autoimmune (PGA) syndrome type I: response to cyclical steroid therapy.
Clinical endocrinology 1991;35(4):299-303.
1991: Tsatsoulis A; Shalet S M; Robertson W R
Bioactive gonadotrophin secretion in man.
Clinical endocrinology 1991;35(3):193-206.
1991: Talbot J A; Lambert A; Mitchell R; Grabinski M; Anderson D C; Tsatsoulis A; Shalet S M; Robertson W R
Follicle-stimulating hormone-dependent estrogen secretion by rat Sertoli cells in vitro: modulation by calcium.
Acta endocrinologica 1991;125(3):280-5.
1991: Crowne E C; Shalet S M; Wallace W H; Eminson D M; Price D A
Final height in girls with untreated constitutional delay in growth and puberty.
European journal of pediatrics 1991;150(10):708-12.
1991: Clayton P E; Shalet S M
The evolution of spinal growth after irradiation.
Clinical oncology (Royal College of Radiologists (Great Britain)) 1991;3(4):220-2.
1991: Littley M D; Shalet S M; Morgenstern G R; Deakin D P
Endocrine and reproductive dysfunction following fractionated total body irradiation in adults.
The Quarterly journal of medicine 1991;78(287):265-74.
1991: Wallace W H; Crowne E C; Shalet S M; Moore C; Gibson S; Littley M D; White A
Episodic ACTH and cortisol secretion in normal children.
Clinical endocrinology 1991;34(3):215-21.
1991: Clayton P E; Shalet S M
Dose dependency of time of onset of radiation-induced growth hormone deficiency.
The Journal of pediatrics 1991;118(2):226-8.
1991: Shalet S M
Growth hormone therapy following bone marrow transplantation in childhood.
Bone marrow transplantation 1991;8 Suppl 1():14.
1990: Littley M D; Pollock A; Kane J; Shalet S M
Basal serum dehydroepiandrosterone sulphate concentration does not predict the cortisol response to provocative testing.
Annals of clinical biochemistry 1990;27 ( Pt 6)():557-61.
1990: Crowne E C; Shalet S M; Wallace W H; Eminson D M; Price D A
Final height in boys with untreated constitutional delay in growth and puberty.
Archives of disease in childhood 1990;65(10):1109-12.
1990: Littley M D; Shalet S M; Beardwell C G; Ahmed S R; Sutton M L
Long-term follow-up of low-dose external pituitary irradiation for Cushing's disease.
Clinical endocrinology 1990;33(4):445-55.
1990: Talbot J A; Shalet S M; Tsatsoulis A; Grabinski M; Robertson W R
Luteinizing hormone pulsatility in men with damage to the germinal epithelium.
International journal of andrology 1990;13(3):223-31.
1990: Talbot J A; Rodger R S; Shalet S M; Littley M D; Robertson W R
The pulsatile secretion of bioactive luteinising hormone in normal adult men.
Acta endocrinologica 1990;122(5):643-50.
1990: Littley M D; Shalet S M; Beardwell C G
Radiation and hypothalamic-pituitary function.
Baillière's clinical endocrinology and metabolism 1990;4(1):147-75.
1990: Littley M D; Shalet S M; Swindell R; Beardwell C G; Sutton M L
Low-dose pituitary irradiation for acromegaly.
Clinical endocrinology 1990;32(2):261-70.
1990: Ward J A; Robinson J; Furr B J; Shalet S M; Morris I D
Protection of spermatogenesis in rats from the cytotoxic procarbazine by the depot formulation of Zoladex, a gonadotropin-releasing hormone agonist.
Cancer research 1990;50(3):568-74.
1990: Tsatsoulis A; Shalet S M; Richardson P; Robertson W R
Testosterone reduces the bioactivity of luteinizing hormone (LH) in man.
Clinical endocrinology 1990;32(1):73-82.
1990: Wallace W H; Shalet S M; Morris-Jones P H; Swindell R; Gattamaneni H R
Effect of abdominal irradiation on growth in boys treated for a Wilms' tumor.
Medical and pediatric oncology 1990;18(6):441-6.
1990: Tsatsoulis A; Shalet S M; Morris I D; de Kretser D M
Immunoactive inhibin as a marker of Sertoli cell function following cytotoxic damage to the human testis.
Hormone research 1990;34(5-6):254-9.
1990: Tsatsoulis A; Morris I D; Shalet S M; Robertson W R; de Kretser D M
Changes in plasma inhibin levels following pulsatile gonadotrophin-releasing hormone therapy in a man with idiopathic hypogonadotrophic hypogonadism.
Hormone research 1990;33(1):18-21.
1989: Littley M D; Gibson S; White A; Shalet S M
Comparison of the ACTH and cortisol responses to provocative testing with glucagon and insulin hypoglycaemia in normal subjects.
Clinical endocrinology 1989;31(5):527-33.
1989: Gibson S; Pollock A; Littley M; Shalet S; White A
Advantages of IRMA over RIA in the measurement of ACTH.
Annals of clinical biochemistry 1989;26 ( Pt 6)():500-7.
1989: Wallace W H; Shalet S M; Hendry J H; Morris-Jones P H; Gattamaneni H R
Ovarian failure following abdominal irradiation in childhood: the radiosensitivity of the human oocyte.
The British journal of radiology 1989;62(743):995-8.
1989: Wallace W H; Shalet S M; Crowne E C; Morris-Jones P H; Gattamaneni H R
Ovarian failure following abdominal irradiation in childhood: natural history and prognosis.
Clinical oncology (Royal College of Radiologists (Great Britain)) 1989;1(2):75-9.
1989: Littley M D; Shalet S M; Beardwell C G; Robinson E L; Sutton M L
Radiation-induced hypopituitarism is dose-dependent.
Clinical endocrinology 1989;31(3):363-73.
1989: Shalet S M
Treatment of constitutional delay in growth and puberty (CDGP).
Clinical endocrinology 1989;31(1):81-6.
1989: Tsatsoulis A; Shalet S M; Talbot A; Robertson W R
Quantitative and qualitative changes in LH secretion following pulsatile GnRH therapy in a man with idiopathic hypogonadotrophic hypogonadism.
Clinical endocrinology 1989;30(2):167-75.
1989: Littley M D; Shalet S M; Beardwell C G; Ahmed S R; Applegate G; Sutton M L
Hypopituitarism following external radiotherapy for pituitary tumours in adults.
The Quarterly journal of medicine 1989;70(262):145-60.
1989: Morris I D; Shalet S M
Endocrine-mediated protection from cytotoxic-induced testicular damage.
The Journal of endocrinology 1989;120(1):7-9.
1989: Shalet S M; Tsatsoulis A; Whitehead E; Read G
Vulnerability of the human Leydig cell to radiation damage is dependent upon age.
The Journal of endocrinology 1989;120(1):161-5.
1989: Wallace W H; Shalet S M; Crowne E C; Morris-Jones P H; Gattamaneni H R; Price D A
Gonadal dysfunction due to cis-platinum.
Medical and pediatric oncology 1989;17(5):409-13.
1988: Tsatsoulis A; Shalet S M; Robertson W R; Morris I D; Burger H G; De Kretser D M
Plasma inhibin levels in men with chemotherapy-induced severe damage to the seminiferous epithelium.
Clinical endocrinology 1988;29(6):659-65.
1988: Tsatsoulis A; Shalet S M; Robertson W R
Changes in the qualitative and quantitative secretion of luteinizing hormone (LH) following orchidectomy in man.
Clinical endocrinology 1988;29(2):189-94.
1988: Tsatsoulis A; Mavroudis K; Frost J; Lambert A; Shalet S M; Robertson W R
The stability in vitro of bioactive and immunoreactive LH in human blood and plasma.
The Journal of endocrinology 1988;117(1):139-45.
1988: Clayton P E; Shalet S M; Morris-Jones P H; Price D A
Growth in children treated for acute lymphoblastic leukaemia.
Lancet 1988;1(8583):460-2.
1988: Tsatsoulis A; Shalet S M; Harrison J; Ratcliffe W A; Beardwell C G; Robinson E L
Adrenocorticotrophin (ACTH) deficiency undetected by standard dynamic tests of the hypothalamic-pituitary-adrenal axis.
Clinical endocrinology 1988;28(2):225-32.
1988: Price D A; Shalet S M; Clayton P E
Management of idiopathic growth hormone deficient patients during puberty.
Acta paediatrica Scandinavica. Supplement 1988;347():44-51.
1988: Shalet S M; Clayton P E; Price D A
Growth and pituitary function in children treated for brain tumours or acute lymphoblastic leukaemia.
Hormone research 1988;30(2-3):53-61.
1988: Clayton P E; Shalet S M; Price D A
Gonadal function after chemotherapy and irradiation for childhood malignancies.
Hormone research 1988;30(2-3):104-10.
1988: Shalet S M; Clayton P E; Price D A
Growth impairment following treatment for childhood brain tumours.
Acta paediatrica Scandinavica. Supplement 1988;343():137-45.
1987: Tsatsoulis A; Whitehead E; St John J; Shalet S M; Robertson W R
The pituitary-Leydig cell axis in men with severe damage to the germinal epithelium.
Clinical endocrinology 1987;27(6):683-9.
1987: Chapman A J; Shalet S M; Beardwell C G; Thatcher N; Robinson E L
Elevated serum alpha subunit levels in patients with cancer; a consequence of gonadotrophin secretion and age.
British journal of cancer 1987;56(4):493-4.
1987: Clayton P E; Shalet S M; Gattamaneni H R; Price D A
Does growth hormone cause relapse of brain tumours?
Lancet 1987;1(8535):711-3.
1987: Surtees R; Adams J; Price D; Clayton P; Shalet S
Association of adverse perinatal events with an empty sella turcica in children with growth hormone deficiency.
Hormone research 1987;28(1):5-12.
1986: Ahmed S R; Shalet S M; Beardwell C G
The effects of cranial irradiation on growth hormone secretion.
Acta paediatrica Scandinavica 1986;75(2):255-60.
1984: Chapman A J; Gallagher J T; Beardwell C G; Shalet S M
Variation in the core and branch carbohydrate sequences of serum glycoprotein hormone alpha subunit as determined by lectin affinity chromatography.
The Journal of endocrinology 1984;103(1):117-22.
1984: Chapman A J; Gallagher J T; Beardwell C G; Shalet S M
Lack of binding of serum glycoprotein hormone alpha subunit to concanavalin A-Sepharose reflects increased branching of the oligosaccharide chains.
The Journal of endocrinology 1984;103(1):111-6.
1984: Ahmed S R; Shalet S M; Beardwell C G; Sutton M L
Treatment of Cushing's disease with low dose radiation therapy.
British medical journal (Clinical research ed.) 1984;289(6446):643-6.
1984: Chapman A J; MacFarlane I A; Shalet S M; Beardwell C G; Dutton J; Sutton M L
Discordant serum alpha-subunit and FSH concentrations in a woman with a pituitary tumour.
Clinical endocrinology 1984;21(2):123-9.
1983: Macfarlane I A; Shalet S M; Beardwell C G; Applegate G; Robinson E L; Sutton M L
External pituitary irradiation as a cause of TRH deficiency in patients with pituitary adenomas.
Clinical endocrinology 1983;18(2):201-9.
1982: Randall S; Laing I; Chapman A J; Shalet S M; Beardwell C G; Kelly W F; Davies D
Pregnancies in women with hyperprolactinaemia: obstetric and endocrinological management of 50 pregnancies in 37 women.
British journal of obstetrics and gynaecology 1982;89(1):20-3.
1981: Shalet S M; Chapman A J; Whitehead E; Beardwell C G
A practical approach to the investigation of the hyperprolactinaemic patient.
Postgraduate medical journal 1981;57(670):485-7.
1981: Shalet S M; Lendon M; Morris Jones P H
Testicular function after chemotherapy for acute lymphoblastic leukemia.
The New England journal of medicine 1981;305(9):520.
1981: Shalet S M; Hann I M; Lendon M; Morris Jones P H; Beardwell C G
Testicular function after combination chemotherapy in childhood for acute lymphoblastic leukaemia.
Archives of disease in childhood 1981;56(4):275-8.
1981: Shalet S M; Whitehead E; Chapman A J; Beardwell C G
The effects of growth hormone therapy in children with radiation-induced growth hormone deficiency.
Acta paediatrica Scandinavica 1981;70(1):81-6.
1980: Macfarlane I A; Beardwell C G; Shalet S M; Darbyshire P J; Hayward E; Sutton M L
Glycoprotein hormone alpha subunit secretion by pituitary adenomas: influence of external irradiation.
Clinical endocrinology 1980;13(3):215-22.
1980: MacFarlane I A; Robinson E L; Bush H; Durning P; Howat J M; Beardwell C G; Shalet S M
Thyroid function in patients with benign and malignant breast disease.
British journal of cancer 1980;41(3):478-80.

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