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Brian Shames

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Myocardial Ischemic Preconditioning

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Brian D Shames; Hazel H Barton; Leonid L Reznikov; Charles Cairns; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.
Casey M Calkins; Denis D Bensard; Brian D Shames; Edward J Pulido; Edward Abraham; Nathan Fernandez; Xianzhong Meng; Charles A Dinarello; Robert C McIntyre
IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Xianzhong Meng; Lihua Ao; Brian D Shames; Alden H Harken
Inhibition of cyclic-3',5'-nucleotide phosphodiesterase abrogates the synergism of hypoxia with lipopolysaccharide in the induction of macrophage TNF-alpha production.

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All Publications

2002: Brian D Shames; Hazel H Barton; Leonid L Reznikov; Charles Cairns; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.
Shock (Augusta, Ga.) 2002;17(2):114-9.
2002: Casey M Calkins; Denis D Bensard; Brian D Shames; Edward J Pulido; Edward Abraham; Nathan Fernandez; Xianzhong Meng; Charles A Dinarello; Robert C McIntyre
IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Journal of endotoxin research 2002;8(1):59-67.
2001: Xianzhong Meng; Lihua Ao; Brian D Shames; Alden H Harken
Inhibition of cyclic-3',5'-nucleotide phosphodiesterase abrogates the synergism of hypoxia with lipopolysaccharide in the induction of macrophage TNF-alpha production.
The Journal of surgical research 2001;101(2):210-5.
2001: Brian D Shames; Robert C McIntyre; Denis D Bensard; Edward J Pulido; Craig H Selzman; Leonid L Reznikov; Alden H Harken; Xianzhong Meng
Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10.
The Journal of surgical research 2001;99(2):187-93.
2001: Casey M Calkins; Denis D Bensard; Julie K Heimbach; Xianzhong Meng; Brian D Shames; Edward J Pulido; Robert C McIntyre
L-arginine attenuates lipopolysaccharide-induced lung chemokine production.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L400-8.
2001: KK Donnahoo; Xianzhong Meng; Lihua Ao; A Ayala; Brian D Shames; M P Cain; Alden H Harken; Daniel R Meldrum
Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia.
Immunology 2001;102(1):53-8.
2000: Robert C McIntyre; Edward J Pulido; Denis D Bensard; Brian D Shames; Edward Abraham
Thirty years of clinical trials in acute respiratory distress syndrome.
Critical care medicine 2000;28(9):3314-31.
2000: Brian D Shames; Garret S Zallen; Robert C McIntyre; Denis D Bensard; Edward J Pulido; SA Miller; Benjamin J Pomerantz; Craig H Selzman; Xianzhong Meng; Alden H Harken
Chemokines as mediators of diseases related to surgical conditions.
Shock (Augusta, Ga.) 2000;14(1):1-7.
2000: Benjamin J Pomerantz; K Joo; Brian D Shames; Joseph C Cleveland; Anirban Banerjee; Alden H Harken
Adenosine preconditioning reduces both pre and postischemic arrhythmias in human myocardium.
The Journal of surgical research 2000;90(2):191-6.
2000: Edward J Pulido; Brian D Shames; David A Fullerton; Brett C Sheridan; Craig H Selzman; Fabia Gamboni-Robertson; Denis D Bensard; Robert C McIntyre
Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(5):R1232-9.
2000: S A Miller; Craig H Selzman; Brian D Shames; HA Barton; S M Johnson; Alden H Harken
Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation.
The Journal of surgical research 2000;90(1):76-81.
2000: Jyoti Arya; Christina Finlayson; Brian D Shames; Alden H Harken; B O Anderson
Stimulated apoptosis as an anti-neoplastic strategy.
Surgery 2000;127(4):366-9.
2000: Leonid L Reznikov; Brian D Shames; HA Barton; Craig H Selzman; Giamila Fantuzzi; S H Kim; S M Johnson; Charles A Dinarello
Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(1):R263-70.
1999: BS Cain; Daniel R Meldrum; Xianzhong Meng; Edward J Pulido; Brian D Shames; Craig H Selzman; Anirban Banerjee; Alden H Harken
Exogenous calcium preconditions myocardium from patients taking oral sulfonylurea agents.
The Journal of surgical research 1999;86(2):171-6.
1999: Edward J Pulido; Brian D Shames; Craig H Selzman; HA Barton; Anirban Banerjee; Denis D Bensard; Robert C McIntyre
Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation.
The American journal of physiology 1999;277(4 Pt 1):L769-76.
1999: Daniel R Meldrum; Xianzhong Meng; Brian D Shames; Benjamin J Pomerantz; KK Donnahoo; Anirban Banerjee; Alden H Harken
Liposomal delivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction.
Surgery 1999;126(2):135-41.
1999: Xianzhong Meng; James M Brown; Lihua Ao; Brian D Shames; Anirban Banerjee; Alden H Harken
Reduction of infarct size in the rat heart by LPS preconditioning is associated with expression of angiogenic growth factors and increased capillary density.
Shock (Augusta, Ga.) 1999;12(1):25-31.
1999: Daniel R Meldrum; BS Cain; Xianzhong Meng; Joseph C Cleveland; Brian D Shames; KK Donnahoo; Anirban Banerjee; Alden H Harken
Calcium preconditioning, but not ischemic preconditioning, bypasses the adenosine triphosphate-dependent potassium (KATP) channel.
The Journal of surgical research 1999;85(1):77-82.
1999: KK Donnahoo; Brian D Shames; Alden H Harken; Daniel R Meldrum
Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury.
The Journal of urology 1999;162(1):196-203.
1999: Xianzhong Meng; Anirban Banerjee; Lihua Ao; Daniel R Meldrum; BS Cain; Brian D Shames; Alden H Harken
Inhibition of myocardial TNF-alpha production by heat shock. A potential mechanism of stress-induced cardioprotection against postischemic dysfunction.
Annals of the New York Academy of Sciences 1999;874():69-82.
1999: Edward J Pulido; Brian D Shames; Diane Pennica; Rhona M O'Leary; Denis D Bensard; BS Cain; Robert C McIntyre
Cardiotrophin-1 attenuates endotoxin-induced acute lung injury.
The Journal of surgical research 1999;84(2):240-6.
1999: Craig H Selzman; Brian D Shames; Robert C McIntyre; Anirban Banerjee; Alden H Harken
The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation.
The Annals of thoracic surgery 1999;67(5):1227-31; discussion 1231-2.
1999: Xianzhong Meng; Brian D Shames; Edward J Pulido; Daniel R Meldrum; Lihua Ao; KS Joo; Alden H Harken; Anirban Banerjee
Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming.
The American journal of physiology 1999;276(5 Pt 2):R1525-33.
1999: Brian D Shames; Craig H Selzman; Edward J Pulido; Xianzhong Meng; Daniel R Meldrum; Robert C McIntyre; Alden H Harken; Anirban Banerjee
LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent.
The Journal of surgical research 1999;83(1):69-74.
1999: BS Cain; Daniel R Meldrum; Xianzhong Meng; C A Dinarello; Brian D Shames; Anirban Banerjee; Alden H Harken
p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function.
The Journal of surgical research 1999;83(1):7-12.
1999: Leonid L Reznikov; Giamila Fantuzzi; Craig H Selzman; Brian D Shames; HA Barton; H Bell; James A McGregor; Charles A Dinarello
Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta.
Biology of reproduction 1999;60(5):1231-8.
1999: Craig H Selzman; Brian D Shames; Leonid L Reznikov; S A Miller; Xianzhong Meng; HA Barton; A Werman; Alden H Harken; Charles A Dinarello; Anirban Banerjee
Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
Circulation research 1999;84(8):867-75.
1998: Craig H Selzman; Daniel R Meldrum; BS Cain; Xianzhong Meng; Brian D Shames; Lihua Ao; Alden H Harken
Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation.
The Journal of surgical research 1998;80(2):352-6.
1998: Brian D Shames; Craig H Selzman; Daniel R Meldrum; Edward J Pulido; HA Barton; Xianzhong Meng; Alden H Harken; Robert C McIntyre
Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes.
Shock (Augusta, Ga.) 1998;10(6):389-94.
1998: Daniel R Meldrum; Charles A Dinarello; Brian D Shames; Joseph C Cleveland; BS Cain; Anirban Banerjee; Xianzhong Meng; Alden H Harken
Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning.
Circulation 1998;98(19 Suppl):II214-8; discussion II218-9.
1998: Craig H Selzman; Brian D Shames; SA Miller; Edward J Pulido; Xianzhong Meng; Robert C McIntyre; Alden H Harken
Therapeutic implications of interleukin-10 in surgical disease.
Shock (Augusta, Ga.) 1998;10(5):309-18.
1998: Daniel R Meldrum; Xianzhong Meng; C A Dinarello; A Ayala; BS Cain; Brian D Shames; Lihua Ao; Anirban Banerjee; Alden H Harken
Human myocardial tissue TNFalpha expression following acute global ischemia in vivo.
Journal of molecular and cellular cardiology 1998;30(9):1683-9.
1998: Brian D Shames; Daniel R Meldrum; Craig H Selzman; Edward J Pulido; BS Cain; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin.
The American journal of physiology 1998;275(3 Pt 2):H1084-91.
1998: Daniel R Meldrum; Brian D Shames; Xianzhong Meng; David A Fullerton; Robert C McIntyre; Frederick L Grover; Alden H Harken
Nitric oxide downregulates lung macrophage inflammatory cytokine production.
The Annals of thoracic surgery 1998;66(2):313-7.
1998: Craig H Selzman; Brian D Shames; Thomas A Whitehill; Alden H Harken; Robert C McIntyre
Class II cytokine receptor ligands inhibit human vascular smooth muscle proliferation.
Surgery 1998;124(2):318-26; discussion 326-7.
1998: Daniel R Meldrum; C A Dinarello; Joseph C Cleveland; BS Cain; Brian D Shames; Xianzhong Meng; Alden H Harken
Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism.
Surgery 1998;124(2):291-6; discussion 297.
1998: Xianzhong Meng; Lihua Ao; Daniel R Meldrum; BS Cain; Brian D Shames; Craig H Selzman; Anirban Banerjee; Alden H Harken
TNF-alpha and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship.
The American journal of physiology 1998;275(2 Pt 2):R502-8.
1998: Brian D Shames; Craig H Selzman; X Meng; Daniel R Meldrum; B S Cain; Alden H Harken
Genes don't count.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(6):667-9.
1998: Craig H Selzman; Robert C McIntyre; Brian D Shames; Thomas A Whitehill; Anirban Banerjee; Alden H Harken
Interleukin-10 inhibits human vascular smooth muscle proliferation.
Journal of molecular and cellular cardiology 1998;30(4):889-96.
1998: BS Cain; Daniel R Meldrum; Xianzhong Meng; Brian D Shames; Anirban Banerjee; Alden H Harken
Calcium preconditioning in human myocardium.
The Annals of thoracic surgery 1998;65(4):1065-70.
1998: Craig H Selzman; Thomas A Whitehill; Brian D Shames; Edward J Pulido; BS Cain; Alden H Harken; B C Cain
The biology of estrogen-mediated repair of cardiovascular injury.
The Annals of thoracic surgery 1998;65(3):868-74.