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Kevin Shannon
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Chemicals & Drugs
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13
Le Beau, Michelle
10
Bollag, Gideon
9
Schubbert, Suzanne
8
Kratz, Christian
8
Loh, Mignon
8
Braun, Benjamin
8
Jacks, Tyler
7
Bonifas, Jeannette
7
Phibbs, Roderic
6
Clapp, Wade
5
Niemeyer, Charlotte
5
Lauchle, Jennifer
5
Kogan, Scott
5
Taylor, Brigit
4
Green, Eric
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All Publications
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2009: Lauchle Jennifer O; Kim Doris; Le Doan T; Akagi Keiko; Crone Michael; Krisman Kimberly; Warner Kegan; Bonifas Jeannette M; Li Qing; Coakley Kristen M; Diaz-Flores Ernesto; Gorman Matthew; Przybranowski Sally; Tran Mary; Kogan Scott C; Roose Jeroen P; Copeland Neal G; Jenkins Nancy A; Parada Luis; Wolff Linda; Sebolt-Leopold Judith; Shannon Kevin
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.
Nature 2009;461(7262):411-4.
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2009: Shannon Kevin; Loh Mignon
Cancer: More than kin and less than kind.
Nature 2009;460(7257):804-7.
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2009: Braun Benjamin S; Shannon Kevin
The SPS affair: a complex tale of illicit proliferation.
Cancer cell 2009;16(2):87-8.
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2009: Loh Mignon L; Sakai Debbie S; Flotho Christian; Kang Michelle; Fliegauf Manfred; Archambeault Sophie; Mullighan Charles G; Chen Leslie; Bergstraesser Eva; Bueso-Ramos Carlos E; Emanuel Peter D; Hasle Henrik; Issa Jean-Pierre; van den Heuvel-Eibrink Marry M; Locatelli Franco; Stary Jan; Trebo Monica; Wlodarski Marcin; Zecca Marco; Shannon Kevin M; Niemeyer Charlotte M
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.
Blood 2009;114(9):1859-63.
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2009: Sabnis Amit J; Cheung Laurene S; Dail Monique; Kang Hio Chung; Santaguida Marianne; Hermiston Michelle L; Passegué Emmanuelle; Shannon Kevin; Braun Benjamin S
Oncogenic Kras initiates leukemia in hematopoietic stem cells.
PLoS biology 2009;7(3):e59.
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2009: Zhang Yan; Wong Jasmine; Klinger Mark; Tran Mary T; Shannon Kevin M; Killeen Nigel
MLL5 contributes to hematopoietic stem cell fitness and homeostasis.
Blood 2009;113(7):1455-63.
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2009: Yin Bin; Delwel Ruud; Valk Peter J; Wallace Margaret R; Loh Mignon L; Shannon Kevin M; Largaespada David A
A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Blood 2009;113(5):1075-85.
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2008: Wong Jasmine C; Le Beau Michelle M; Shannon Kevin
Tumor suppressor gene inactivation in myeloid malignancies.
Best practice & research. Clinical haematology 2008;21(4):601-14.
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2008: Kotecha Nikesh; Flores Nikki J; Irish Jonathan M; Simonds Erin F; Sakai Debbie S; Archambeault Sophie; Diaz-Flores Ernesto; Coram Marc; Shannon Kevin M; Nolan Garry P; Loh Mignon L
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.
Cancer cell 2008;14(4):335-43.
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2008: Haigis Kevin M; Kendall Krystle R; Wang Yufang; Cheung Ann; Haigis Marcia C; Glickman Jonathan N; Niwa-Kawakita Michiko; Sweet-Cordero Alejandro; Sebolt-Leopold Judith; Shannon Kevin M; Settleman Jeffrey; Giovannini Marco; Jacks Tyler
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Nature genetics 2008;40(5):600-8.
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2008: Braun Benjamin S; Shannon Kevin
Targeting Ras in myeloid leukemias.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(8):2249-52.
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2008: Lange Beverly J; Smith Franklin O; Feusner James; Barnard Dorothy R; Dinndorf Patricia; Feig Stephen; Heerema Nyla A; Arndt Carola; Arceci Robert J; Seibel Nita; Weiman Margie; Dusenbery Kathryn; Shannon Kevin; Luna-Fineman Sandra; Gerbing Robert B; Alonzo Todd A
Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the children's oncology group.
Blood 2008;111(3):1044-53.
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2008: Denayer Ellen; Parret Annabel; Chmara Magdalena; Schubbert Suzanne; Vogels Annick; Devriendt Koen; Frijns Jean-Pierre; Rybin Vladimir; de Ravel Thomy J; Shannon Kevin; Cools Jan; Scheffzek Klaus; Legius Eric
Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.
Human mutation 2008;29(2):232-9.
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2008: Shannon Kevin M; Le Beau Michelle M
Cancer: hay in a haystack.
Nature 2008;451(7176):252-3.
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2007: Schubbert Suzanne; Bollag Gideon; Lyubynska Natalya; Nguyen Hoa; Kratz Christian P; Zenker Martin; Niemeyer Charlotte M; Molven Anders; Shannon Kevin
Biochemical and functional characterization of germ line KRAS mutations.
Molecular and cellular biology 2007;27(22):7765-70.
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2007: Diaz-Flores Ernesto; Shannon Kevin
Targeting oncogenic Ras.
Genes & development 2007;21(16):1989-92.
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2007: Søvik Oddmund; Schubbert Suzanne; Houge Gunnar; Steine Solrun J; Norgård Gunnar; Engelsen Bernt; Njølstad Pål R; Shannon Kevin; Molven Anders
De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features.
Journal of medical genetics 2007;44(7):e84.
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2007: Zhang Yi; Diaz-Flores Ernesto; Li Geqiang; Wang Zhengqi; Kang Zizhen; Haviernikova Eleonora; Rowe Sara; Qu Cheng-Kui; Tse William; Shannon Kevin M; Bunting Kevin D
Abnormal hematopoiesis in Gab2 mutant mice.
Blood 2007;110(1):116-24.
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2007: Van Meter Margaret E M; Díaz-Flores Ernesto; Archard Joehleen A; Passegué Emmanuelle; Irish Jonathan M; Kotecha Nikesh; Nolan Garry P; Shannon Kevin; Braun Benjamin S
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells.
Blood 2007;109(9):3945-52.
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2007: Schubbert Suzanne; Shannon Kevin; Bollag Gideon
Hyperactive Ras in developmental disorders and cancer.
Nature reviews. Cancer 2007;7(4):295-308.
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2007: Schubbert Suzanne; Bollag Gideon; Shannon Kevin
Deregulated Ras signaling in developmental disorders: new tricks for an old dog.
Current opinion in genetics & development 2007;17(1):15-22.
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2007: Kim Andrew; Morgan Kelly; Hasz Diane E; Wiesner Stephen M; Lauchle Jennifer O; Geurts Jennifer L; Diers Miechaleen D; Le Doan T; Kogan Scott C; Parada Luis F; Shannon Kevin; Largaespada David A
Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.
Blood 2007;109(4):1687-91.
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2007: Shannon Kevin; Bollag Gideon
Sending out an SOS.
Nature genetics 2007;39(1):8-9.
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2006: Braun Benjamin S; Archard Joehleen A; Van Ziffle Jessica A G; Tuveson David A; Jacks Tyler E; Shannon Kevin
Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
Blood 2006;108(6):2041-4.
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2006: Stephens Karen; Weaver Molly; Leppig Kathleen A; Maruyama Kyoko; Emanuel Peter D; Le Beau Michelle M; Shannon Kevin M
Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies.
Blood 2006;108(5):1684-9.
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2006: Kratz Christian P; Schubbert Suzanne; Bollag Gideon; Niemeyer Charlotte M; Shannon Kevin M; Zenker Martin
Germline mutations in components of the Ras signaling pathway in Noonan syndrome and related disorders.
Cell cycle (Georgetown, Tex.) 2006;5(15):1607-11.
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2006: Loh Mignon L; Goldwasser Meredith A; Silverman Lewis B; Poon Wing-Man; Vattikuti Shashaank; Cardoso Angelo; Neuberg Donna S; Shannon Kevin M; Sallan Stephen E; Gilliland D Gary
Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01.
Blood 2006;107(11):4508-13.
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2006: Lauchle Jennifer O; Braun Benjamin S; Loh Mignon L; Shannon Kevin
Inherited predispositions and hyperactive Ras in myeloid leukemogenesis.
Pediatric blood & cancer 2006;46(5):579-85.
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2006: Gutmann David H; Hunter-Schaedle Kim; Shannon Kevin M
Harnessing preclinical mouse models to inform human clinical cancer trials.
The Journal of clinical investigation 2006;116(4):847-52.
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2006: Schubbert Suzanne; Zenker Martin; Rowe Sara L; Böll Silke; Klein Cornelia; Bollag Gideon; van der Burgt Ineke; Musante Luciana; Kalscheuer Vera; Wehner Lars-Erik; Nguyen Hoa; West Brian; Zhang Kam Y J; Sistermans Erik; Rauch Anita; Niemeyer Charlotte M; Shannon Kevin; Kratz Christian P
Germline KRAS mutations cause Noonan syndrome.
Nature genetics 2006;38(3):331-6.
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2005: Chao Richard C; Pyzel Urszula; Fridlyand Jane; Kuo Yien-Ming; Teel Lewis; Haaga Jennifer; Borowsky Alexander; Horvai Andrew; Kogan Scott C; Bonifas Jeannette; Huey Bing; Jacks Tyler E; Albertson Donna G; Shannon Kevin M
Therapy-induced malignant neoplasms in Nf1 mutant mice.
Cancer cell 2005;8(4):337-48.
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2005: Arceci Robert J; Sande Jane; Lange Beverly; Shannon Kevin; Franklin Janet; Hutchinson Raymond; Vik Terry A; Flowers David; Aplenc Richard; Berger Mark S; Sherman Matthew L; Smith Franklin O; Bernstein Irwin; Sievers Eric L
Safety and efficacy of gemtuzumab ozogamicin in pediatric patients with advanced CD33+ acute myeloid leukemia.
Blood 2005;106(4):1183-8.
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2005: Schubbert Suzanne; Lieuw Kenneth; Rowe Sara L; Lee Connie M; Li Xiaxin; Loh Mignon L; Clapp D Wade; Shannon Kevin M
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells.
Blood 2005;106(1):311-7.
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2005: Curtiss Nicole P; Bonifas Jeannette M; Lauchle Jennifer O; Balkman Jason D; Kratz Christian P; Emerling Brooke M; Green Eric D; Le Beau Michelle M; Shannon Kevin M
Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22.
Genomics 2005;85(5):600-7.
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2005: Shannon Kevin; Van Etten Richard A
JAKing up hematopoietic proliferation.
Cancer cell 2005;7(4):291-3.
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2005: Germeshausen M; Schulze H; Kratz C; Wilkens L; Repp R; Shannon K; Welte K; Ballmaier M
An acquired G-CSF receptor mutation results in increased proliferation of CMML cells from a patient with severe congenital neutropenia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(4):611-7.
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2005: Katsumoto Tamiko R; Duda Jennifer; Kim Andrew; Wardak Zabihullah; Dranoff Glenn; Clapp D Wade; Shannon Kevin
Granulocyte/macrophage colony-stimulating factor and accessory cells modulate radioprotection by purified hematopoietic cells.
The Journal of experimental medicine 2005;201(6):853-8.
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2004: Van Etten Richard A; Shannon Kevin M
Focus on myeloproliferative diseases and myelodysplastic syndromes.
Cancer cell 2004;6(6):547-52.
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2004: Le Doan T; Kong Namie; Zhu Yuan; Lauchle Jennifer O; Aiyigari Abigail; Braun Benjamin S; Wang Endi; Kogan Scott C; Le Beau Michelle M; Parada Luis; Shannon Kevin M
Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.
Blood 2004;103(11):4243-50.
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2004: Braun Benjamin S; Shannon Kevin
The sum is greater than the FGFR1 partner.
Cancer cell 2004;5(3):203-4.
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2004: Side Lucy E; Curtiss Nicole P; Teel Kathryn; Kratz Christian; Wang Pauline W; Larson Richard A; Le Beau Michelle M; Shannon Kevin M
RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.
Genes, chromosomes & cancer 2004;39(3):217-23.
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2004: Loh Mignon L; Vattikuti Shashaank; Schubbert Suzanne; Reynolds Melissa G; Carlson Elaine; Lieuw Kenneth H; Cheng Jennifer W; Lee Connie M; Stokoe David; Bonifas Jeannette M; Curtiss Nicole P; Gotlib Jason; Meshinchi Soheil; Le Beau Michelle M; Emanuel Peter D; Shannon Kevin M
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.
Blood 2004;103(6):2325-31.
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2004: Braun Benjamin S; Tuveson David A; Kong Namie; Le Doan T; Kogan Scott C; Rozmus Jacob; Le Beau Michelle M; Jacks Tyler E; Shannon Kevin M
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):597-602.
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2004: Tartaglia Marco; Niemeyer Charlotte M; Shannon Kevin M; Loh Mignon L
SHP-2 and myeloid malignancies.
Current opinion in hematology 2004;11(1):44-50.
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2003: Kratz Christian P; Antonietti Letizia; Shannon Kevin M; Dole Mukund G; Friebert Sarah E
Acute myeloid leukemia associated with t(8;21) or trisomy 8 in children with neurofibromatosis, type 1.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2003;25(4):343.
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2003: Aiyagari Abigail L; Taylor Brigit R; Aurora Vikas; Young Stephen G; Shannon Kevin M
Hematologic effects of inactivating the Ras processing enzyme Rce1.
Blood 2003;101(6):2250-2.
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2003: Ingram David A; Wenning Mary Jo; Shannon Kevin; Clapp D Wade
Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.
Blood 2003;101(5):1984-6.
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2003: Weiss Brian; Shannon Kevin
Mouse cancer models as a platform for performing preclinical therapeutic trials.
Current opinion in genetics & development 2003;13(1):84-9.
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2002: Donovan Shane; See Wendy; Bonifas Jeannette; Stokoe David; Shannon Kevin M
Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells.
Cancer cell 2002;2(6):507-14.
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2002: Downing James R; Shannon Kevin M
Acute leukemia: a pediatric perspective.
Cancer cell 2002;2(6):437-45.
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2002: Houghton Peter J; Adamson Peter C; Blaney Susan; Fine Howard A; Gorlick Richard; Haber Michelle; Helman Lee; Hirschfeld Steve; Hollingshead Melinda G; Israel Mark A; Lock Richard B; Maris John M; Merlino Glenn; Patterson Wendy; Reynolds C Patrick; Shannon Kevin; Yu Alice; Yu John; Smith Malcolm A
Testing of new agents in childhood cancer preclinical models: meeting summary.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3646-57.
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2002: Shannon Kevin M
Resistance in the land of molecular cancer therapeutics.
Cancer cell 2002;2(2):99-102.
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2002: Dror Yigal; Durie Peter; Ginzberg Hedy; Herman Rebecca; Banerjee Anu; Champagne Martin; Shannon Kevin; Malkin David; Freedman Melvin H
Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.
Experimental hematology 2002;30(7):659-69.
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2002: Emerling Brooke M; Bonifas Jeannette; Kratz Christian P; Donovan Shane; Taylor Brigit R; Green Eric D; Le Beau Michelle M; Shannon Kevin M
MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia.
Oncogene 2002;21(31):4849-54.
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2002: Le Doan Thuy; Shannon Kevin M
Ras processing as a therapeutic target in hematologic malignancies.
Current opinion in hematology 2002;9(4):308-15.
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2002: Donovan Shane; Shannon Kevin M; Bollag Gideon
GTPase activating proteins: critical regulators of intracellular signaling.
Biochimica et biophysica acta 2002;1602(1):23-45.
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2002: Kratz Christian P; Emerling Brooke M; Bonifas Jeannette; Wang Winfred; Green Eric D; Le Beau Michelle M; Shannon Kevin M
Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor.
Blood 2002;99(1):372-4.
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2001: Banerjee A; Shannon K M
Leukemic transformation in patients with severe congenital neutropenia.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2001;23(8):487-95.
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2001: Kratz C P; Emerling B M; Donovan S; Laig-Webster M; Taylor B R; Thompson P; Jensen S; Banerjee A; Bonifas J; Makalowski W; Green E D; Le Beau M M; Shannon K M
Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies.
Genomics 2001;77(3):171-80.
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2001: Zhang Y; Taylor B R; Shannon K; Clapp D W
Quantitative effects of Nf1 inactivation on in vivo hematopoiesis.
The Journal of clinical investigation 2001;108(5):709-15.
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2001: Shannon K M; Le Beau M M; Largaespada D A; Killeen N
Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse.
Seminars in cancer biology 2001;11(3):191-200.
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2000: Cooper L J; Shannon K M; Loken M R; Weaver M; Stephens K; Sievers E L
Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell.
Blood 2000;96(6):2310-3.
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2000: Birnbaum R A; O'Marcaigh A; Wardak Z; Zhang Y Y; Dranoff G; Jacks T; Clapp D W; Shannon K M
Nf1 and Gmcsf interact in myeloid leukemogenesis.
Molecular cell 2000;5(1):189-95.
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2000: Ingram D A; Yang F C; Travers J B; Wenning M J; Hiatt K; New S; Hood A; Shannon K; Williams D A; Clapp D W
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.
The Journal of experimental medicine 2000;191(1):181-8.
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1999: Mahgoub N; Taylor B R; Gratiot M; Kohl N E; Gibbs J B; Jacks T; Shannon K M
In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells.
Blood 1999;94(7):2469-76.
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1999: Mantadakis E; Shannon K M; Singer D A; Finklestein J; Chan K W; Hilden J M; Sandler E S
Transient monosomy 7: a case series in children and review of the literature.
Cancer 1999;85(12):2655-61.
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1999: Mahgoub N; Taylor B R; Le Beau M M; Gratiot M; Carlson K M; Atwater S K; Jacks T; Shannon K M
Myeloid malignancies induced by alkylating agents in Nf1 mice.
Blood 1999;93(11):3617-23.
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1999: Weiss B; Bollag G; Shannon K
Hyperactive Ras as a therapeutic target in neurofibromatosis type 1.
American journal of medical genetics 1999;89(1):14-22.
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1999: Fernandez M C; Weiss B; Atwater S; Shannon K; Matthay K K
Congenital leukemia: successful treatment of a newborn with t(5;11)(q31;q23).
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 1999;21(2):152-7.
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1999: Kim E; Ambroziak P; Otto J C; Taylor B; Ashby M; Shannon K; Casey P J; Young S G
Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.
The Journal of biological chemistry 1999;274(13):8383-90.
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1999: Luna-Fineman S; Shannon K M; Atwater S K; Davis J; Masterson M; Ortega J; Sanders J; Steinherz P; Weinberg V; Lange B J
Myelodysplastic and myeloproliferative disorders of childhood: a study of 167 patients.
Blood 1999;93(2):459-66.
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1998: Side L E; Emanuel P D; Taylor B; Franklin J; Thompson P; Castleberry R P; Shannon K M
Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1.
Blood 1998;92(1):267-72.
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1998: Shannon K
Genetic predispositions and childhood cancer.
Environmental health perspectives 1998;106 Suppl 3():801-6.
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1998: Zhang Y Y; Vik T A; Ryder J W; Srour E F; Jacks T; Shannon K; Clapp D W
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines.
The Journal of experimental medicine 1998;187(11):1893-902.
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1998: Frenck R W; Blackburn E H; Shannon K M
The rate of telomere sequence loss in human leukocytes varies with age.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5607-10.
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1998: Mahgoub N; Parker R I; Hosler M R; Close P; Winick N J; Masterson M; Shannon K M; Felix C A
RAS mutations in pediatric leukemias with MLL gene rearrangements.
Genes, chromosomes & cancer 1998;21(3):270-5.
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1997: O'Marcaigh A S; Shannon K M
Role of the NF1 gene in leukemogenesis and myeloid growth control.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 1997;19(6):551-4.
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1997: Side L E; Shannon K M
Myeloid disorders in infants with Noonan syndrome and a resident's "rule" recalled.
The Journal of pediatrics 1997;130(6):857-9.
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1997: Side L; Taylor B; Cayouette M; Conner E; Thompson P; Luce M; Shannon K
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders.
The New England journal of medicine 1997;336(24):1713-20.
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1997: Maris J M; Wiersma S R; Mahgoub N; Thompson P; Geyer R J; Hurwitz C G; Lange B J; Shannon K M
Monosomy 7 myelodysplastic syndrome and other second malignant neoplasms in children with neurofibromatosis type 1.
Cancer 1997;79(7):1438-46.
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1996: Bollag G; Adler F; elMasry N; McCabe P C; Conner E; Thompson P; McCormick F; Shannon K
Biochemical characterization of a novel KRAS insertion mutation from a human leukemia.
The Journal of biological chemistry 1996;271(51):32491-4.
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1996: Miles D K; Freedman M H; Stephens K; Pallavicini M; Sievers E L; Weaver M; Grunberger T; Thompson P; Shannon K M
Patterns of hematopoietic lineage involvement in children with neurofibromatosis type 1 and malignant myeloid disorders.
Blood 1996;88(11):4314-20.
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1996: Emanuel P D; Shannon K M; Castleberry R P
Juvenile myelomonocytic leukemia: molecular understanding and prospects for therapy.
Molecular medicine today 1996;2(11):468-75.
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1996: Gutmann D H; Gurney J G; Shannon K M
Juvenile xanthogranuloma, neurofibromatosis 1, and juvenile chronic myeloid leukemia.
Archives of dermatology 1996;132(11):1390-1.
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1996: Bollag G; Clapp D W; Shih S; Adler F; Zhang Y Y; Thompson P; Lange B J; Freedman M H; McCormick F; Jacks T; Shannon K
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells.
Nature genetics 1996;12(2):144-8.
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1995: Kalra R; Dale D; Freedman M; Bonilla M A; Weinblatt M; Ganser A; Bowman P; Abish S; Priest J; Oseas R S; Olson K; Paderanga D; Shannon K
Monosomy 7 and activating RAS mutations accompany malignant transformation in patients with congenital neutropenia.
Blood 1995;86(12):4579-86.
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1995: Shannon K
Recombinant human erythropoietin in neonatal anemia.
Clinics in perinatology 1995;22(3):627-40.
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1995: Jensen S; Paderanga D C; Chen P; Olson K; Edwards M; Iavorone A; Israel M A; Shannon K
Molecular analysis at the NF1 locus in astrocytic brain tumors.
Cancer 1995;76(4):674-7.
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1995: Shannon K
The Ras signaling pathway and the molecular basis of myeloid leukemogenesis.
Current opinion in hematology 1995;2(4):305-8.
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1995: Luna-Fineman S; Shannon K M; Lange B J
Childhood monosomy 7: epidemiology, biology, and mechanistic implications.
Blood 1995;85(8):1985-99.
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1995: Shannon K M; Keith J F; Mentzer W C; Ehrenkranz R A; Brown M S; Widness J A; Gleason C A; Bifano E M; Millard D D; Davis C B
Recombinant human erythropoietin stimulates erythropoiesis and reduces erythrocyte transfusions in very low birth weight preterm infants.
Pediatrics 1995;95(1):1-8.
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1995: Butcher M; Frenck R; Emperor J; Paderanga D; Maybee D; Olson K; Shannon K
Molecular evidence that childhood monosomy 7 syndrome is distinct from juvenile chronic myelogenous leukemia and other childhood myeloproliferative disorders.
Genes, chromosomes & cancer 1995;12(1):50-7.
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1994: Kalra R; Paderanga D C; Olson K; Shannon K M
Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras.
Blood 1994;84(10):3435-9.
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1994: Lau R C; Squire J; Brisson L; Kamel-Reid S; Grunberger T; Dubé I; Letarte M; Shannon K; Freedman M H
Lymphoid blast crisis of B-lineage phenotype with monosomy 7 in a patient with juvenile chronic myelogenous leukemia (JCML).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(5):903-8.
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1994: Shannon K M; O'Connell P; Martin G A; Paderanga D; Olson K; Dinndorf P; McCormick F
Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders.
The New England journal of medicine 1994;330(9):597-601.
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1994: Savage P; Frenck R; Paderanga D; Emperor J; Shannon K M
Parental origins of chromosome 7 loss in childhood monosomy 7 syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(3):485-9.
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1993: Shannon K
Recombinant erythropoietin in anemia of prematurity: five years later.
Pediatrics 1993;92(4):614-7.
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1993: Kobayashi H; Espinosa R; Thirman M J; Fernald A A; Shannon K; Diaz M O; Le Beau M M; Rowley J D
Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization.
Genes, chromosomes & cancer 1993;7(4):204-8.
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1993: Frenck R W; Shannon K M
Hematopoietic growth factors in pediatrics.
Current opinion in pediatrics 1993;5(1):94-102.
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1992: Shannon K M; Turhan A G; Rogers P C; Kan Y W
Evidence implicating heterozygous deletion of chromosome 7 in the pathogenesis of familial leukemia associated with monosomy 7.
Genomics 1992;14(1):121-5.
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1992: Shannon K
Genetic alterations in leukemia: events on a grand scale.
Blood 1992;80(1):1-2.
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1992: Shannon K M; Mentzer W C; Abels R I; Wertz M; Thayer-Moriyama J; Li W Y; Thompson D; Decelle S; Phibbs R H
Enhancement of erythropoiesis by recombinant human erythropoietin in low birth weight infants: a pilot study.
The Journal of pediatrics 1992;120(4 Pt 1):586-92.
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1992: Shannon K M; Watterson J; Johnson P; O'Connell P; Lange B; Shah N; Steinherz P; Kan Y W; Priest J R
Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type 1: epidemiology and molecular analysis.
Blood 1992;79(5):1311-8.
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1992: Phibbs R H; Shannon K M; Mentzer W C
Potential for treatment of anaemia of prematurity with recombinant human erythropoietin: preliminary results.
Acta haematologica 1992;87 Suppl 1():28-33.
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1991: Shannon K M; Mentzer W C; Abels R I; Freeman P; Newton N; Thompson D; Sniderman S; Ballard R; Phibbs R H
Recombinant human erythropoietin in the anemia of prematurity: results of a placebo-controlled pilot study.
The Journal of pediatrics 1991;118(6):949-55.
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1991: Neubauer A; Shannon K; Liu E
Mutations of the ras proto-oncogenes in childhood monosomy 7.
Blood 1991;77(3):594-8.
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1991: Mentzer W C; Shannon K M; Abels R I; Freeman P; Newton N; Thompson D; Phibbs R H
A randomized, placebo-controlled clinical trial of recombinant human erythropoietin in the anemia of prematurity.
Contributions to nephrology 1991;88():306-12; discussion 313.
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1990: George J W; Bracco C A; Shannon K M; Davis G J; Smith I L; Phibbs R H; Hendrickx A G
Age-related differences in erythropoietic response to recombinant human erythropoietin: comparison in adult and infant rhesus monkeys.
Pediatric research 1990;28(6):567-71.
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1990: Shannon K M; Ring D B; Houston L L; Schaffner V; Naylor J; Torkildson J C; Reid S A; Larrick J
Inhibition of hematopoietic progenitor colony growth by a monoclonal antibody against the transferrin receptor: comparison of unconjugated antibody with an immunotoxin containing recombinant ricin A chain.
International journal of cell cloning 1990;8(5):368-76.
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1990: Shannon K M
Recombinant erythropoietin in pediatrics: a clinical perspective.
Pediatric annals 1990;19(3):197-206.
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1990: Shannon K; Koehne W; Heyman M B; Koerper M A
Relapsing post-hepatitis aplastic anemia. Immunosuppressive therapy.
Clinical pediatrics 1990;29(1):25-9.
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1990: Shannon K M
Anemia of prematurity: progress and prospects.
The American journal of pediatric hematology/oncology 1990;12(1):14-20.
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1989: Shannon K M; Turhan A G; Chang S S; Bowcock A M; Rogers P C; Carroll W L; Cowan M J; Glader B E; Eaves C J; Eaves A C
Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7.
The Journal of clinical investigation 1989;84(3):984-9.
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1989: Phibbs R H; Shannon K; Mentzer W C
Rationale for using recombinant human erythropoietin to treat the anemia of prematurity.
Contributions to nephrology 1989;76():324-8; discussion 328-9.
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1989: Shannon K M; Clemons G K; Torkildson J C; Buchanan G R; Mentzer W C
Spontaneous resolution of primary erythrocytosis in two girls.
Pediatric hematology and oncology 1989;6(4):373-82.
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1988: Cowan M J; Shannon K M; Wara D W; Ammann A J
Rejection of bone marrow transplant and resistance of alloantigen reactive cells to in vivo deoxyadenosine in adenosine deaminase deficiency.
Clinical immunology and immunopathology 1988;49(2):242-50.
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1987: Shannon K M; Naylor G S; Torkildson J C; Clemons G K; Schaffner V; Goldman S L; Lewis K; Bryant P; Phibbs R
Circulating erythroid progenitors in the anemia of prematurity.
The New England journal of medicine 1987;317(12):728-33.
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1987: Hogge D E; Shannon K M; Kalousek D K; Schonberg S; Schaffner V; Zoger S; Eaves C J; Eaves A C
Juvenile monosomy 7 syndrome: evidence that the disease originates in a pluripotent hemopoietic stem cell.
Leukemia research 1987;11(8):705-9.
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1986: Shannon K M; Larrick J W; Fulcher S A; Burck K B; Pacely J; Davis J C; Ring D B
Selective inhibition of the growth of human erythroid bursts by monoclonal antibodies against transferrin or the transferrin receptor.
Blood 1986;67(6):1631-8.
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1986: Shannon K; Nunez G; Dow L W; Weinberg A G; Sato Y; Stastny P; Buchanan G R
Juvenile chronic myelogenous leukemia: surface antigen phenotyping by monoclonal antibodies and cytogenetic studies.
Pediatrics 1986;77(3):330-5.
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1985: Shannon K; Cowan M J; Ball E; Abrams D; Volberding P; Ammann A J
Impaired mononuclear-cell proliferation in patients with the acquired immune deficiency syndrome results from abnormalities of both T lymphocytes and adherent mononuclear cells.
Journal of clinical immunology 1985;5(4):239-45.
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1984: Shannon K M; Buchanan G R; Fink C W; Stastny P
Lymphocyte populations in childhood idiopathic thrombocytopenic purpura.
American journal of diseases of children (1960) 1984;138(1):64-5.
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1983: Shannon K; Ball E; Wasserman R L; Murphy F K; Luby J; Buchanan G R
Transfusion-associated cytomegalovirus infection and acquired immune deficiency syndrome in an infant.
The Journal of pediatrics 1983;103(6):859-63.
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1983: Shannon K; Fink C W; Buchanan G R; Punaro M; Stastny P
Lymphocyte subpopulations in Kawasaki disease.
Clinical and experimental rheumatology 1983;1(1):59-62.
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1982: Shannon K; Buchanan G R
Severe hemolytic anemia in black children with glucose-6-phosphate dehydrogenase deficiency.
Pediatrics 1982;70(3):364-9.
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1982: Shannon K; Buchanan G R; Votteler T P
Multiple hepatic hemangiomas: failure of corticosteroid therapy and successful hepatic artery ligation.
American journal of diseases of children (1960) 1982;136(3):275-6.
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