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James Shapiro

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Anatomy

Islets of Langerhans

Disorders

Type 1 Diabetes Mellitus

Physiology

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Publications

TOP 3
McCall Michael D; Toso Christian; Baetge Emmanuel E; Shapiro A M James
Are stem cells a cure for diabetes?
Kin Tatsuya; Shapiro A M James
Circumportal pancreas and islet isolation.
Truong Wayne; Hancock Wayne W; Plester Jennifer C; Merani Shaheed; Rayner David C; Thangavelu Govindarajan; Murphy Kenneth M; Anderson Colin C; Shapiro A M James
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice.

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All Publications

2010: McCall Michael D; Toso Christian; Baetge Emmanuel E; Shapiro A M James
Are stem cells a cure for diabetes?
Clinical science (London, England : 1979) 2010;118(2):87-97.
2009: Kin Tatsuya; Shapiro A M James
Circumportal pancreas and islet isolation.
Surgery 2009;146(1):126-7.
2009: Truong Wayne; Hancock Wayne W; Plester Jennifer C; Merani Shaheed; Rayner David C; Thangavelu Govindarajan; Murphy Kenneth M; Anderson Colin C; Shapiro A M James
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice.
Journal of leukocyte biology 2009;86(1):41-51.
2009: Kin Tatsuya; O'Gorman Doug; Zhai Xiaojun; Pawlick Rena; Imes Sharleen; Senior Peter; Shapiro A M James
Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation.
Transplantation 2009;87(11):1700-5.
2009: Emamaullee Juliet; Toso Christian; Merani Shaheed; Shapiro A M James
Costimulatory blockade with belatacept in clinical and experimental transplantation - a review.
Expert opinion on biological therapy 2009;9(6):789-96.
2009: Emamaullee Juliet A; Davis Joy; Merani Shaheed; Toso Christian; Elliott John F; Thiesen Aducio; Shapiro A M James
Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.
Diabetes 2009;58(6):1302-11.
2009: Alfadhli Eman; Koh Angela; Albaker Waleed; Bhargava Ravi; Ackerman Thomas; McDonald Charlotte; Ryan Edmond A; Shapiro A M James; Senior Peter A
High prevalence of ovarian cysts in premenopausal women receiving sirolimus and tacrolimus after clinical islet transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(6):622-5.
2009: Owen Richard J; Mercer John R; Al-Saif Faisal; Molinari Michele; Ashforth Robert A; Rajotte Ray V; Conner-Spady Barbara; Shapiro A M James
Portal vein embolization with radiolabeled polyvinyl alcohol particles in a swine model: hepatic distribution and implications for pancreatic islet cell transplantation.
Cardiovascular and interventional radiology 2009;32(3):499-507.
2009: Emamaullee Juliet A; Merani Shaheed; Toso Christian; Kin Tatsuya; Al-Saif Faisal; Truong Wayne; Pawlick Rena; Davis Joy; Edgar Ryan; Lock Jennifer; Bonner-Weir Susan; Knudsen Lotte B; Shapiro A M James
Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide.
Endocrinology 2009;150(5):2145-52.
2009: Toso Christian; Asthana Sonal; Bigam David L; Shapiro A M James; Kneteman Norman M
Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the Scientific Registry of Transplant Recipients database.
Hepatology (Baltimore, Md.) 2009;49(3):832-8.
2009: Toso Christian; Edgar Ryan; Pawlick Rena; Emamaullee Juliet; Merani Shaheed; Dinyari Parastoo; Mueller Thomas F; Shapiro A M James; Anderson Colin C
Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(2):182-91.
2009: Merani Shaheed; Pawlick Rena L; Edgar Ryan L; Toso Christian; Emamaullee Juliet; Anderson Colin C; Shapiro A M James
Protein kinase C inhibitor, AEB-071, acts complementarily with cyclosporine to prevent islet rejection in rats.
Transplantation 2009;87(1):59-65.
2008: Kin Tatsuya; O'Neil John J; Pawlick Rena; Korbutt Gregory S; Shapiro A M James; Lakey Jonathan R T
The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment.
Artificial organs 2008;32(12):990-3.
2008: Merani S; Toso C; Emamaullee J; Shapiro A M J
Optimal implantation site for pancreatic islet transplantation.
The British journal of surgery 2008;95(12):1449-61.
2008: Toso Christian; Serre-Beinier Véronique; Emamaullee Juliet; Merani Shaheed; Armanet Mathieu; Wojtusciszyn Anne; Bosco Domenico; Calandra Thierry; Roger Thierry; Morel Philippe; Shapiro A M James; Berney Thierry
The role of macrophage migration inhibitory factor in mouse islet transplantation.
Transplantation 2008;86(10):1361-9.
2008: Kin Tatsuya; Zhai Xiaojun; O'Gorman Doug; Shapiro Andrew Mark James
Detrimental effect of excessive collagenase class II on human islet isolation outcome.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(11):1059-65.
2008: Toso C; Emamaullee J A; Merani S; Shapiro A M J
The role of macrophage migration inhibitory factor on glucose metabolism and diabetes.
Diabetologia 2008;51(11):1937-46.
2008: Kin Tatsuya; Senior Peter; O'Gorman Doug; Richer Brad; Salam Abdul; Shapiro Andrew Mark James
Risk factors for islet loss during culture prior to transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(11):1029-35.
2008: Merani S; Truong W; Emamaullee J A; Toso C; Knudsen L B; Shapiro A M J
Liraglutide, a long-acting human glucagon-like peptide 1 analog, improves glucose homeostasis in marginal mass islet transplantation in mice.
Endocrinology 2008;149(9):4322-8.
2008: Davis Vanessa W; Somani Karim; Chaba Todd P; Andruchow Jennifer; Shapiro A M James
Hepatic artery aneurysm secondary to epithelioid angiosarcoma.
Canadian journal of surgery. Journal canadien de chirurgie 2008;51(4):E81-2.
2008: Toso Christian; Trotter James; Wei Alice; Bigam David L; Shah Shimul; Lancaster Joshua; Grant David R; Greig Paul D; Shapiro A M James; Kneteman Norman M
Total tumor volume predicts risk of recurrence following liver transplantation in patients with hepatocellular carcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(8):1107-15.
2008: Ricordi Camillo; Hering Berhard J; Shapiro A M James;
Beta-cell transplantation for diabetes therapy.
Lancet 2008;372(9632):27-8; author reply 29-30.
2008: Emamaullee Juliet A; Davis Joy; Pawlick Rena; Toso Christian; Merani Shaheed; Cai Sui-Xiong; Tseng Ben; Shapiro A M James
The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice.
Diabetes 2008;57(6):1556-66.
2008: Chan William F N; Razavy Haide; Luo Bin; Shapiro A M James; Anderson Colin C
Development of either split tolerance or robust tolerance along with humoral tolerance to donor and third-party alloantigens in nonmyeloablative mixed chimeras.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5177-86.
2008: Hering Bernhard J; Sykes Megan; Sutherland David E R; Shapiro A M James; Tremblay Jacques P
The first Joint Conference of the Cell Transplant Society (CTS), International Pancreas and Islet Transplant Association (IPITA), and International Xenotransplantation Association (IXA), all sections of The Transplantation Society (TTS), took place in Minneapolis, Minn, USA, from September 15-20, 2007. Preface.
Transplantation proceedings 2008;40(2):335-6.
2008: Emamaullee Juliet A; Merani Shaheed; Larsen Christian P; Shapiro A M James
Belatacept and basiliximab diminish human antiporcine xenoreactivity and synergize to inhibit alloimmunity.
Transplantation 2008;85(1):118-24.
2008: Truong Wayne; Shapiro A M James
The TIM family of cosignaling receptors: emerging targets for the regulation of autoimmune disease and transplantation tolerance.
Cell transplantation 2008;16(10):977-86.
2007: Truong W; Plester J C; Hancock W W; Merani S; Murphy T L; Murphy K M; Kaye J; Anderson C C; Shapiro A M J
Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(12):2663-74.
2007: Truong Wayne; Plester Jennifer C; Hancock Wayne W; Kaye Jonathan; Merani Shaheed; Murphy Kenneth M; Murphy Theresa L; Anderson Colin C; Shapiro A M James
Negative and positive co-signaling with anti-BTLA (PJ196) and CTLA4Ig prolongs islet allograft survival.
Transplantation 2007;84(10):1368-72.
2007: Campbell P M; Senior P A; Salam A; Labranche K; Bigam D L; Kneteman N M; Imes S; Halpin A; Ryan E A; Shapiro A M J
High risk of sensitization after failed islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(10):2311-7.
2007: Toso Christian; Shapiro A M James; Bowker Samantha; Dinyari Parastoo; Paty Breay; Ryan Edmond A; Senior Peter; Johnson Jeffrey A
Quality of life after islet transplant: impact of the number of islet infusions and metabolic outcome.
Transplantation 2007;84(5):664-6.
2007: Toso Christian; Meeberg Glenda A; Bigam David L; Oberholzer Jose; Shapiro A M James; Gutfreund Klaus; Ma Mang M; Mason Andrew L; Wong Winnie W S; Bain Vincent G; Kneteman Norman M
De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects.
Transplantation 2007;83(9):1162-8.
2007: Shapiro A M James; Sutherland David E R
The new deceased donor pancreas allocation schema: do the recommendations go far enough?
Transplantation 2007;83(9):1151-2.
2007: Campbell P M; Salam A; Ryan E A; Senior P; Paty B W; Bigam D; McCready T; Halpin A; Imes S; Al Saif F; Lakey J R T; Shapiro A M J
Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(5):1242-8.
2007: Luo Bin; Chan William F N; Shapiro A M James; Anderson Colin C
Non-myeloablative mixed chimerism approaches and tolerance, a split decision.
European journal of immunology 2007;37(5):1233-42.
2007: Kin T; Zhai X; Murdoch T B; Salam A; Shapiro A M James; Lakey Jonathan R T
Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(5):1233-41.
2007: Emamaullee Juliet A; Stanton Laura; Schur Colleen; Shapiro A M James
Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation.
Diabetes 2007;56(5):1289-98.
2007: Suchak Amar A; O'Kelly Kevin; Al Saif F; Shapiro A M James; Owen Richard J
Hepatic artery-portal venous fistula after percutaneous intraportal islet cell transplant.
Transplantation 2007;83(5):669-70.
2007: Walter M; McDonald C G; Paty B W; Shapiro A M J; Ryan E A; Senior P A
Prevalence of autoimmune diseases in islet transplant candidates with severe hypoglycaemia and glycaemic lability: previously undiagnosed coeliac and autoimmune thyroid disease is identified by screening.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(2):161-5.
2007: Senior P A; Zeman M; Paty B W; Ryan E A; Shapiro A M James
Changes in renal function after clinical islet transplantation: four-year observational study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(1):91-8.
2007: Kin Tatsuya; Johnson Paul R V; Shapiro A M James; Lakey Jonathan R T
Factors influencing the collagenase digestion phase of human islet isolation.
Transplantation 2007;83(1):7-12.
2007: Luo B; Chan W F N; Lord S J; Nanji S A; Rajotte R V; Shapiro A M J; Anderson C C
Diabetes induces rapid suppression of adaptive immunity followed by homeostatic T-cell proliferation.
Scandinavian journal of immunology 2007;65(1):22-31.
2007: Lakey Jonathan R T; Kin Tatsuya; Warnock Garth L; Shapiro A M James; Tsapogas Panagiotis; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Rajotte Ray V; Ryan Edmond A
Long-term graft function after allogeneic islet transplantation.
Cell transplantation 2007;16(4):441-6.
2007: Kin Tatsuya; Rosichuk Shawn; Shapiro A M James; Lakey Jonathan R T
Detection of microbial contamination during human islet isolation.
Cell transplantation 2007;16(1):9-13.
2007: Emamaullee Juliet A; Shapiro A M James
Factors influencing the loss of beta-cell mass in islet transplantation.
Cell transplantation 2007;16(1):1-8.
2006: Matsumoto Shinichi; Okitsu Teru; Iwanaga Yasuhiro; Noguchi Hirofumi; Nagata Hideo; Yonekawa Yukihide; Liu Xiaoling; Kamiya Hiroki; Ueda Michiko; Hatanaka Nobuyo; Kobayashi Naoya; Yamada Yuichiro; Miyakawa Shuichi; Seino Yutaka; Shapiro A M James; Tanaka Koichi
Follow-up study of the first successful living donor islet transplantation.
Transplantation 2006;82(12):1629-33.
2006: Merani Shaheed; Schur Colleen; Truong Wayne; Knutzen Victor K; Lakey Jonathan R T; Anderson Colin C; Ricordi Camillo; Shapiro A M James
Compaction of islets is detrimental to transplant outcome in mice.
Transplantation 2006;82(11):1472-6.
2006: Kin Tatsuya; Mirbolooki Mohammadreza; Salehi Payam; Tsukada Manabu; O'Gorman Doug; Imes Sharleen; Ryan Edmond A; Shapiro A M James; Lakey Jonathan R T
Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using preoxygenated perfluorocarbon.
Transplantation 2006;82(10):1286-90.
2006: Emamaullee Juliet A; Shapiro A M James; Rajotte Ray V; Korbutt Greg; Elliott John F
Neonatal porcine islets exhibit natural resistance to hypoxia-induced apoptosis.
Transplantation 2006;82(7):945-52.
2006: Al-Saif Faisal; Al-Masloom Abdulmuttalib; Johnson Mary Anne; Bain Vincent G; Sandha Gurpal Singh; Ritchie D Bruce C; Shapiro A M James
Autoimmune pancreatitis with autoimmune hemolytic anemia.
Pancreas 2006;33(3):316-7.
2006: Bussiere C T; Lakey J R T; Shapiro A M J; Korbutt G S
The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells.
Diabetologia 2006;49(10):2341-9.
2006: Emamaullee Juliet A; Shapiro A M James
Interventional strategies to prevent beta-cell apoptosis in islet transplantation.
Diabetes 2006;55(7):1907-14.
2006: Merani Shaheed; Shapiro A M James
Current status of pancreatic islet transplantation.
Clinical science (London, England : 1979) 2006;110(6):611-25.
2006: Alsaif Faisal; Molinari Michele; Al-Masloom Abdulmuttalib; Lakey Jonathan R T; Kin Tatsuya; Shapiro A M James
Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma.
Pancreas 2006;32(4):430-1.
2006: Paty Breay W; Senior Peter A; Lakey Jonathan R T; Shapiro A M James; Ryan Edmond A
Assessment of glycemic control after islet transplantation using the continuous glucose monitor in insulin-independent versus insulin-requiring type 1 diabetes subjects.
Diabetes technology & therapeutics 2006;8(2):165-73.
2006: Nanji Sulaiman A; Hancock Wayne W; Luo Bin; Schur Colleen D; Pawlick Rena L; Zhu Lin Fu; Anderson Colin C; Shapiro A M James
Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse.
Diabetes 2006;55(1):27-33.
2006: Nanji Sulaiman A; Shapiro A M James
Advances in pancreatic islet transplantation in humans.
Diabetes, obesity & metabolism 2006;8(1):15-25.
2006: Ryan Edmond A; Bigam David; Shapiro A M James
Current indications for pancreas or islet transplant.
Diabetes, obesity & metabolism 2006;8(1):1-7.
2006: Merani Shaheed; Truong Wayne W; Hancock Wayne; Anderson Colin C; Shapiro A M James
Chemokines and their receptors in islet allograft rejection and as targets for tolerance induction.
Cell transplantation 2006;15(4):295-309.
2006: Lakey Jonathan R T; Mirbolooki Mohammadreza; Shapiro A M James
Current status of clinical islet cell transplantation.
Methods in molecular biology (Clifton, N.J.) 2006;333():47-104.
2006: Salehi Payam; Mirbolooki Mohammadreza; Kin Tatsuya; Tsujimura Toshiaki; Shapiro A M James; Churchill Thomas A; Lakey Jonathan R T
Ameliorating injury during preservation and isolation of human islets using the two-layer method with perfluorocarbon and UW solution.
Cell transplantation 2006;15(2):187-94.
2006: Kin Tatsuya; Murdoch Travis B; Shapiro A M James; Lakey Jonathan R T
Estimation of pancreas weight from donor variables.
Cell transplantation 2006;15(2):181-5.
2006: Truong Wayne; Hancock Wayne W; Anderson Colin C; Merani Shaheed; Shapiro A M James
Coinhibitory T-cell signaling in islet allograft rejection and tolerance.
Cell transplantation 2006;15(2):105-19.
2006: Truong Wayne; Shapiro A M James
Progress in islet transplantation in patients with type 1 diabetes mellitus.
Treatments in endocrinology 2006;5(3):147-58.
2005: Villiger P; Ryan E A; Owen R; O'Kelly K; Oberholzer J; Al Saif F; Kin T; Wang H; Larsen I; Blitz S L; Menon V; Senior P; Bigam D L; Paty B; Kneteman N M; Lakey J R T; Shapiro A M James
Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(12):2992-8.
2005: Molinari Michele; Al-Saif Faisal; Ryan Edmond A; Lakey Jonathan R T; Senior Peter A; Paty Breay W; Bigam David L; Kneteman Norman M; Shapiro A M James
Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(11):2799-804.
2005: O'Gorman D; Kin T; McGhee-Wilson D; Shapiro A M J; Lakey J R T
Multi-lot analysis of custom collagenase enzyme blend in human islet isolations.
Transplantation proceedings 2005;37(8):3417-9.
2005: Barnett Matthew J; Zhai Xiaojun; LeGatt Donald F; Cheng Siew Bang; Shapiro A M James; Lakey Jonathan R T
Quantitative assessment of collagenase blends for human islet isolation.
Transplantation 2005;80(6):723-8.
2005: Emamaullee Juliet A; Rajotte Ray V; Liston Peter; Korneluk Robert G; Lakey Jonathan R T; Shapiro A M James; Elliott John F
XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes.
Diabetes 2005;54(9):2541-8.
2005: Senior Peter A; Paty Breay W; Cockfield Sandra M; Ryan Edmond A; Shapiro A M James
Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(9):2318-23.
2005: Griffiths Jill; Sia Winnie; Shapiro A M James; Tataryn Ivanna; Turner A Robert
Laparoscopic splenectomy for the treatment of refractory immune thrombocytopenia in pregnancy.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2005;27(8):771-4.
2005: Luo Bin; Nanji Sulaiman A; Schur Colleen D; Pawlick Rena L; Anderson Colin C; Shapiro A M James
Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning.
Transplantation 2005;80(3):370-7.
2005: Ryan Edmond A; Paty Breay W; Senior Peter A; Bigam David; Alfadhli Eman; Kneteman Norman M; Lakey Jonathan R T; Shapiro A M James
Five-year follow-up after clinical islet transplantation.
Diabetes 2005;54(7):2060-9.
2005: Emamaullee Juliet; Liston Peter; Korneluk Robert G; Shapiro A M James; Elliott John F
XIAP overexpression in islet beta-cells enhances engraftment and minimizes hypoxia-reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1297-305.
2005: Gaglia Jason L; Shapiro A M James; Weir Gordon C
Islet transplantation: progress and challenge.
Archives of medical research 2005;36(3):273-80.
2005: Shapiro A M James; Lakey Jonathan R T; Paty Breay W; Senior Peter A; Bigam David L; Ryan Edmond A
Strategic opportunities in clinical islet transplantation.
Transplantation 2005;79(10):1304-7.
2005: Kin Tatsuya; Shapiro A M James; Lakey Jonathan R T
Pancreas divisum: a study of the cadaveric donor pancreas for islet isolation.
Pancreas 2005;30(4):325-7.
2005: Senior Peter A; Welsh Robert C; McDonald Charlotte G; Paty Breay W; Shapiro A M James; Ryan Edmond A
Coronary artery disease is common in nonuremic, asymptomatic type 1 diabetic islet transplant candidates.
Diabetes care 2005;28(4):866-72.
2005: O'Gorman D; Kin T; Murdoch T; Richer B; McGhee-Wilson D; Ryan E; Shapiro A M J; Lakey J R T
The standardization of pancreatic donors for islet isolation.
Transplantation proceedings 2005;37(2):1309-10.
2005: Ryan Edmond A; Paty Breay W; Senior Peter A; Lakey Jonathan R T; Bigam David; Shapiro A M James
Beta-score: an assessment of beta-cell function after islet transplantation.
Diabetes care 2005;28(2):343-7.
2005: Shapiro A M James; Gallant Heather L; Hao Er Geng; Lakey Jonathan R T; McCready Tara; Rajotte Ray V; Yatscoff Randall W; Kneteman Norman M
The portal immunosuppressive storm: relevance to islet transplantation?
Therapeutic drug monitoring 2005;27(1):35-7.
2005: Truong Wayne; Lakey Jonathan R T; Ryan Edmond A; Shapiro A M James
Clinical islet transplantation at the University of Alberta--the Edmonton experience.
Clinical transplants 2005;():153-72.
2004: Street Cale N; Lakey Jonathan R T; Shapiro A M James; Imes Sharleen; Rajotte Ray V; Ryan Edmond A; Lyon James G; Kin Tatsuya; Avila Jose; Tsujimura Toshiaki; Korbutt Gregory S
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome.
Diabetes 2004;53(12):3107-14.
2004: Kneteman Norman M; Oberholzer José; Al Saghier Mohammed; Meeberg Glenda A; Blitz Maurice; Ma Mang M; Wong Winnie W S; Gutfreund Klaus; Mason Andrew L; Jewell Larry D; Shapiro A M James; Bain Vincent G; Bigam David L
Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(10):1301-11.
2004: Senior Peter A; Shapiro A M James; Ackerman Thomas E; Ryan Edmond A; Paty Breay W; Bhargava Ravi
Magnetic resonance-defined perinephric edema after clinical islet transplantation: a benign finding associated with mild renal impairment.
Transplantation 2004;78(6):945-8.
2004: McDonald Charlotte G; Ryan Edmond A; Paty Breay W; Senior Peter A; Marshall Sally M; Lakey Jonathan R T; Shapiro A M James
Cross-sectional and prospective association between proinsulin secretion and graft function after clinical islet transplantation.
Transplantation 2004;78(6):934-7.
2004: Ryan Edmond A; Paty Breay W; Senior Peter A; Shapiro A M James
Risks and side effects of islet transplantation.
Current diabetes reports 2004;4(4):304-9.
2004: Tsujimura Toshiaki; Kuroda Yoshikazu; Avila Jose G; Kin Tatsuya; Oberholzer Jose; Shapiro A M James; Lakey Jonathan R T
Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method.
Transplantation 2004;78(1):96-100.
2004: Bhargava Ravi; Senior Peter A; Ackerman Thomas E; Ryan Edmond A; Paty Breay W; Lakey Jonathan R T; Shapiro A M James
Prevalence of hepatic steatosis after islet transplantation and its relation to graft function.
Diabetes 2004;53(5):1311-7.
2004: Paty Breay W; Bonner-Weir Susan; Laughlin Maren R; McEwan Alexander J; Shapiro A M James
Toward development of imaging modalities for islets after transplantation: insights from the National Institutes of Health Workshop on Beta Cell Imaging.
Transplantation 2004;77(8):1133-7.
2004: Ryan Edmond A; Shandro Tami; Green Kristy; Paty Breay W; Senior Peter A; Bigam David; Shapiro A M James; Vantyghem Marie-Christine
Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation.
Diabetes 2004;53(4):955-62.
2004: Nanji Sulaiman A; Hancock Wayne W; Anderson Colin C; Adams Andrew B; Luo Bin; Schur Colleen D; Pawlick Rena L; Wang Liqing; Coyle Anthony J; Larsen Christian P; Shapiro A M James
Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(4):526-36.
2004: Shapiro A M James; Ricordi Camillo
Unraveling the secrets of single donor success in islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(3):295-8.
2004: Egawa Hiroto; Oike Fumitaka; Buhler Leo; Shapiro A M James; Minamiguchi Sachiko; Haga Hironori; Uryuhara Kenji; Kiuchi Tetsuya; Kaihara Satoshi; Tanaka Koichi
Impact of recipient age on outcome of ABO-incompatible living-donor liver transplantation.
Transplantation 2004;77(3):403-11.
2004: Street C N; Lakey J R T; Seeberger K; Helms L; Rajotte R V; Shapiro A M J; Korbutt G S
Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker.
The Journal of endocrinology 2004;180(2):213-25.
2004: Johnson Jeffrey A; Kotovych Maria; Ryan Edmond A; Shapiro A M James
Reduced fear of hypoglycemia in successful islet transplantation.
Diabetes care 2004;27(2):624-5.
2004: Street Cale N; Lakey Jonathan R T; Rajotte Ray V; Shapiro A M James; Kieffer Timothy J; Lyon James G; Kin Tatsuya; Korbutt Gregory S
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently.
The review of diabetic studies : RDS 2004;1(2):66-79.
2004: Murdoch T B; McGhee-Wilson D; Shapiro A M J; Lakey J R T
Methods of human islet culture for transplantation.
Cell transplantation 2004;13(6):605-17.
2004: Barnett M J; McGhee-Wilson D; Shapiro A M J; Lakey J R T
Variation in human islet viability based on different membrane integrity stains.
Cell transplantation 2004;13(5):481-8.
2004: Nanji Sulaiman A; Shapiro A M James
Islet transplantation in patients with diabetes mellitus: choice of immunosuppression.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2004;18(5):315-28.
2004: Rose Natisha L; Palcic Monica M; Shapiro A M James; Lakey Jonathan R T
Endogenous pancreatic enzyme activity levels show no significant effect on human islet isolation yield.
Cell transplantation 2004;13(2):153-60.
2004: Tsujimura Toshiaki; Kuroda Yoshikazu; Churchill Thomas A; Avila Jose G; Kin Tatsuya; Shapiro A M James; Lakey Jonathan R T
Short-term storage of the ischemically damaged human pancreas by the two-layer method prior to islet isolation.
Cell transplantation 2004;13(1):67-73.
2003: Shapiro A M James; Nanji Sulaiman A; Lakey Jonathan R T
Clinical islet transplant: current and future directions towards tolerance.
Immunological reviews 2003;196():219-36.
2003: Rafael Ehab; Ryan Edmond A; Paty Breay W; Oberholzer Jose; Imes Sharleen; Senior Peter; McDonald Charlotte; Lakey Jonathan R T; Shapiro A M James
Changes in liver enzymes after clinical islet transplantation.
Transplantation 2003;76(9):1280-4.
2003: Nanji S A; Hancock W W; Anderson C C; Zhu L F; Kneteman N M; Shapiro A M J
Combination therapy with anti-ICOS and cyclosporine enhances cardiac but not islet allograft survival.
Transplantation proceedings 2003;35(7):2477-8.
2003: Tsujimura T; Kuroda Y; Avila J G; Kin T; Churchill T A; Shapiro A M J; Lakey J R T
Resuscitation of the ischemically damaged human pancreas by the two-layer method prior to islet isolation.
Transplantation proceedings 2003;35(7):2461-2.
2003: Rose N L; Palcic M M; Shapiro A M J; Lakey J R T
An evaluation of endogenous pancreatic enzyme levels following enzymatic digestion.
Transplantation proceedings 2003;35(7):2458-60.
2003: Rose N L; Palcic M M; Shapiro A M J; Lakey J R T
An evaluation of the activation of endogenous pancreatic enzymes during human islet isolations.
Transplantation proceedings 2003;35(7):2455-7.
2003: Shapiro A M James; Ricordi Camillo; Hering Bernhard
Edmonton's islet success has indeed been replicated elsewhere.
Lancet 2003;362(9391):1242.
2003: Owen Richard J T; Ryan Edmond A; O'Kelly Kevin; Lakey Jonathan R T; McCarthy Mairin C; Paty Breay W; Bigam David L; Kneteman Norman M; Korbutt Gregory S; Rajotte Ray V; Shapiro A M James
Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects.
Radiology 2003;229(1):165-70.
2003: Lakey Jonathan R T; Burridge Philip W; Shapiro A M James
Technical aspects of islet preparation and transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(9):613-32.
2003: Shapiro A M James
Islet transplants and impact on secondary diabetic complications: does C-Peptide protect the kidney?
Journal of the American Society of Nephrology : JASN 2003;14(8):2214-6.
2003: Orive Gorka; Hernández Rosa María; Gascón Alicia R; Calafiore Riccardo; Chang Thomas M S; De Vos Paul; Hortelano Gonzalo; Hunkeler David; Lacík Igor; Shapiro A M James; Pedraz José Luis
Cell encapsulation: promise and progress.
Nature medicine 2003;9(1):104-7.
2003: Avila J G; Tsujimura T; Oberholzer J; Churchill T; Salehi P; Shapiro A M James; Lakey J R T
Improvement of pancreatic islet isolation outcomes using glutamine perfusion during isolation procedure.
Cell transplantation 2003;12(8):877-81.
2003: Oberholzer José; Shapiro A M; Lakey Jonathan R; Ryan Edmond A; Rajotte Ray V; Korbutt Gregory S; Morel Philippe; Kneteman Norman M
Current status of islet cell transplantation.
Advances in surgery 2003;37():253-82.
2002: Lakey Jonathan R T; Tsujimura Toshiaki; Shapiro A M James; Kuroda Yoshikazu
Preservation of the human pancreas before islet isolation using a two-layer (UW solution-perfluorochemical) cold storage method.
Transplantation 2002;74(12):1809-11.
2002: Tsujimura Toshiaki; Kuroda Yoshikazu; Kin Tatsuya; Avila Jose G; Rajotte Ray V; Korbutt Gregory S; Ryan Edmond A; Shapiro A M James; Lakey Jonathan R T
Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method.
Transplantation 2002;74(12):1687-91.
2002: Burridge P W; Shapiro A M J; Ryan E A; Lakey J R T
Future trends in clinical islet transplantation.
Transplantation proceedings 2002;34(8):3347-8.
2002: Shapiro A M James; Geng Hao Er; Lakey Jonathan R T; Finegood Diane T; Rajotte Ray V; Kneteman Norman M
Defining optimal immunosuppression for islet transplantation based on reduced diabetogenicity in canine islet autografts.
Transplantation 2002;74(11):1522-8.
2002: Paty Breay W; Ryan Edmond A; Shapiro A M James; Lakey Jonathan R T; Robertson R Paul
Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence.
Diabetes 2002;51(12):3428-34.
2002: Casey John J; Lakey Jonathan R; Ryan Edmond A; Paty Breay W; Owen Richard; O'Kelly Kevin; Nanji Sulaiman; Rajotte Ray V; Korbutt Gregory S; Bigam David; Kneteman Norman N; Shapiro A M
Portal venous pressure changes after sequential clinical islet transplantation.
Transplantation 2002;74(7):913-5.
2002: Ryan Edmond A; Lakey Jonathan R T; Paty Breay W; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Bigam David; Rajotte Ray V; Shapiro A M James
Successful islet transplantation: continued insulin reserve provides long-term glycemic control.
Diabetes 2002;51(7):2148-57.
2002: Lakey Jonathan R T; Kneteman Norman M; Rajotte Ray V; Wu Douglas C; Bigam David; Shapiro A M James
Effect of core pancreas temperature during cadaveric procurement on human islet isolation and functional viability.
Transplantation 2002;73(7):1106-10.
2002: Rabinovitch Alex; Suarez-Pinzon Wilma L; Shapiro A M James; Rajotte Ray V; Power Robert
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.
Diabetes 2002;51(3):638-45.
2002: Shapiro A M J; Suarez-Pinzon W L; Power R; Rabinovitch A
Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice.
Diabetologia 2002;45(2):224-30.
2001: Shapiro A M; Ryan E A; Lakey J R
Diabetes. Islet cell transplantation.
Lancet 2001;358 Suppl():S21.
2001: Shapiro A M; Ryan E A; Lakey J R
Clinical islet transplant--state of the art.
Transplantation proceedings 2001;33(7-8):3502-3.
2001: Ryan E A; Lakey J R; Shapiro A M
Clinical results after islet transplantation.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(6):559-62.
2001: Lakey J R; Helms L M; Kin T; Korbutt G S; Rajotte R V; Shapiro A M; Warnock G L
Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia.
Transplantation 2001;72(4):565-70.
2001: Albishri S H; Issa S; Kneteman N M; Shapiro A M
Bile leak from duct of Luschka after liver transplantation.
Transplantation 2001;72(2):338-40.
2001: Shapiro A M; Ryan E A; Lakey J R
Pancreatic islet transplantation in the treatment of diabetes mellitus.
Best practice & research. Clinical endocrinology & metabolism 2001;15(2):241-64.
2001: Shapiro A M; Hao E G; Lakey J R; Yakimets W J; Churchill T A; Mitlianga P G; Papadopoulos G K; Elliott J F; Rajotte R V; Kneteman N M
Novel approaches toward early diagnosis of islet allograft rejection.
Transplantation 2001;71(12):1709-18.
2001: Ryan E A; Lakey J R; Rajotte R V; Korbutt G S; Kin T; Imes S; Rabinovitch A; Elliott J F; Bigam D; Kneteman N M; Warnock G L; Larsen I; Shapiro A M
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol.
Diabetes 2001;50(4):710-9.
2000: Shapiro A M; Lakey J R; Ryan E A; Korbutt G S; Toth E; Warnock G L; Kneteman N M; Rajotte R V
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
The New England journal of medicine 2000;343(4):230-8.
2000: Shapiro A M; Lakey J R
Future trends in islet cell transplantation.
Diabetes technology & therapeutics 2000;2(3):449-52.
2000: Shapiro A M; Bain V G; Preiksaitis J K; Ma M M; Issa S; Kneteman N M
Ogilvie's syndrome associated with acute cytomegaloviral infection after liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2000;13(1):41-5.
1999: Asonuma K; Shapiro A M; Inomata Y; Uryuhara K; Uemoto S; Tanaka K
Living related liver transplantation from donors with the left-sided gallbladder/portal vein anomaly.
Transplantation 1999;68(10):1610-2.
1999: Lakey J R; Warnock G L; Shapiro A M; Korbutt G S; Ao Z; Kneteman N M; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Cell transplantation 1999;8(3):285-92.
1999: Yabe S; Nishizawa H; Egawa H; Nakayama H; Okamoto S; Kiuchi T; Uemoto S; Asonuma K; Shapiro A M; Inomata Y; Yamaoka Y; Tanaka K
Portal blood flow and liver regeneration in auxiliary partial orthotopic liver transplantation in a canine model.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1999;31(1):83-92.
1998: Yabe S; Egawa H; Inomata Y; Uemoto S; Asonuma K; Kiuchi T; Nishizawa H; Shapiro A M; Yamaoka Y; Tanaka K
Auxiliary partial orthotopic liver transplantation from living donors: significance of portal blood flow.
Transplantation 1998;66(4):484-8.
1998: Dai C L; Kume M; Yamamoto Y; Yamagami K; Yamamoto H; Nakayama H; Ozaki N; Shapiro A M; Yamamoto M; Yamaoka Y
Heat shock protein 72 production in liver tissue after experimental total hepatic inflow occlusion.
The British journal of surgery 1998;85(8):1061-5.
1998: Shapiro A M; Hao E; Lakey J R; Elliott J F; Rajotte R V; Kneteman N M
Development of diagnostic markers for islet allograft rejection.
Transplantation proceedings 1998;30(2):647.
1998: Shapiro A M; Gallant H; Hao E; Wong J; Rajotte R; Yatscoff R; Kneteman N
Portal vein immunosuppressant levels and islet graft toxicity.
Transplantation proceedings 1998;30(2):641.
1998: Shapiro A M; Hao E; Lakey J R; Finegood D; Rajotte R V; Kneteman N M
Diabetogenic synergism in canine islet autografts from cyclosporine and steroids in combination.
Transplantation proceedings 1998;30(2):527.
1998: Lakey J R; Warnock G L; Ao Z; Shapiro A M; Korbutt G; Kneteman N; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Transplantation proceedings 1998;30(2):359.
1996: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
High yield of rodent islets with intraductal collagenase and stationary digestion--a comparison with standard technique.
Cell transplantation 1996;5(6):631-8.
1996: Yanchar N L; Shapiro A M; Sigalet D L
Is early response to portoenterostomy predictive of long-term outcome for patients with biliary atresia?
Journal of pediatric surgery 1996;31(6):774-8.
1996: Shapiro A M; Bain V G; Sigalet D L; Kneteman N M
Rapid resolution of chylous ascites after liver transplantation using somatostatin analog and total parenteral nutrition.
Transplantation 1996;61(9):1410-1.
1996: Langman L J; Shapiro A M; Lakey J R; LeGatt D F; Kneteman N M; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid in a canine model.
Transplantation proceedings 1996;28(2):934-6.
1996: Lakey J R; Warnock G L; Rajotte R V; Suarez-Alamazor M E; Ao Z; Shapiro A M; Kneteman N M
Variables in organ donors that affect the recovery of human islets of Langerhans.
Transplantation 1996;61(7):1047-53.
1996: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
Impact of Lazaroid U74006F on ischemia and reperfusion injury of islets after transplantation in the rat.
Transplantation proceedings 1996;28(1):85-6.
1996: Langman L J; Shapiro A M; Lakey J R; LeGatt D F; Kneteman N M; Yatscoff R W
Pharmacodynamic assessment of mycophenolic acid-induced immunosuppression by measurement of inosine monophosphate dehydrogenase activity in a canine model.
Transplantation 1996;61(1):87-92.
1995: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
Stationary digestion after intraductal collagenase improves islet recovery in the rat.
Transplantation proceedings 1995;27(6):3378.
1995: Lakey J R; Warnock G L; Rajotte R V; Ao Z; Suarez-Almazor M E; Shapiro A M; Kneteman N M
Factors in cadaveric donors that affect recovery of human islets of Langerhans.
Transplantation proceedings 1995;27(6):3265.
1995: Shapiro A M; Lakey J R; Rajotte R V; Warnock G L; Friedlich M S; Jewell L D; Kneteman N M
Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft.
Transplantation 1995;59(7):1060-3.

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