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Bernard Shapiro

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TOP 3
Chellappagounder Thangavel; Ettickan Boopathi; Bernard H Shapiro
Inherent sex-dependent regulation of human hepatic CYP3A5.
Rajat Kumar Das; Sarmistha Banerjee; Bernard H Shapiro
Noncanonical suppression of GH-dependent isoforms of cytochrome P450 by the somatostatin analog octreotide.
Rajat K Das; Sarmistha Banerjee; Bernard H Shapiro
Extensive sex- and/or hormone-dependent expression of rat housekeeping genes.

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All Publications

2013: Chellappagounder Thangavel; Ettickan Boopathi; Bernard H Shapiro
Inherent sex-dependent regulation of human hepatic CYP3A5.
British journal of pharmacology 2013;168(4):988-1000.
2013: Rajat Kumar Das; Sarmistha Banerjee; Bernard H Shapiro
Noncanonical suppression of GH-dependent isoforms of cytochrome P450 by the somatostatin analog octreotide.
The Journal of endocrinology 2013;216(1):87-97.
2013: Rajat K Das; Sarmistha Banerjee; Bernard H Shapiro
Extensive sex- and/or hormone-dependent expression of rat housekeeping genes.
Endocrine research 2013;38(2):105-11.
2012: Meena R Sharma; Wojciech Dworakowski; Bernard H Shapiro
Intrasplenic transplantation of isolated adult rat hepatocytes: sex-reversal and/or suppression of the major constituent isoforms of cytochrome P450.
Toxicologic pathology 2012;40(1):83-92.
2011: Chellappagounder Thangavel; Ettickan Boopathi; Bernard H Shapiro
Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.
Endocrinology 2011;152(12):4813-24.
2008: Chellappagounder Thangavel; Bernard H Shapiro
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(9):1884-95.
2007: Chellappagounder Thangavel; Ravindra N Dhir; Denys Volgin; Bernard H Shapiro
Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone.
Biochemical pharmacology 2007;74(10):1476-84.
2007: Ravindra N Dhir; Chellappagounder Thangavel; Bernard H Shapiro
Attenuated expression of episodic growth hormone-induced CYP2C11 in female rats associated with suboptimal activation of the Jak2/Stat5B and other modulating signaling pathways.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(11):2102-10.
2007: Chellappagounder Thangavel; Bernard H Shapiro
A molecular basis for the sexually dimorphic response to growth hormone.
Endocrinology 2007;148(6):2894-903.
2006: Ashish S Verma; Bernard H Shapiro
Sex-dependent expression of seven housekeeping genes in rat liver.
Journal of gastroenterology and hepatology 2006;21(6):1004-8.
2006: Chellappagounder Thangavel; Wojciech Dworakowski; Bernard H Shapiro
Inducibility of male-specific isoforms of cytochrome p450 by sex-dependent growth hormone profiles in hepatocyte cultures from male but not female rats.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(3):410-9.
2006: Ravindra N Dhir; Wojciech Dworakowski; Chellappagounder Thangavel; Bernard H Shapiro
Sexually dimorphic regulation of hepatic isoforms of human cytochrome p450 by growth hormone.
The Journal of pharmacology and experimental therapeutics 2006;316(1):87-94.
2005: Arun K Agrawal; Bernard H Shapiro
Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):470-2.
2005: Ashish S Verma; Ravindra N Dhir; Bernard H Shapiro
Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation of hepatic CYP2C11.
Molecular pharmacology 2005;67(3):891-901.
2004: Chellappagounder Thangavel; Martha C Garcia; Bernard H Shapiro
Intrinsic sex differences determine expression of growth hormone-regulated female cytochrome P450s.
Molecular and cellular endocrinology 2004;220(1-2):31-9.
2003: Ravindra N Dhir; Bernard H Shapiro
Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15224-8.
2003: Meena R Sharma; Parameswaran Periandythevar; Bernard H Shapiro
Spurious observation of splenic cyp2b1 expression.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(9):1074-6.
2003: Arun K Agrawal; Bernard H Shapiro
Phenobarbital-imprinted overinduction of adult constituent CYP isoforms.
Pharmacology 2003;68(4):204-15.
2003: Arun K Agrawal; Bernard H Shapiro
Constitutive and inducible hepatic cytochrome P450 isoforms in senescent male and female rats and response to low-dose phenobarbital.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(5):612-9.
2002: Antje Kaufhold; Prabhat K Nigam; Ravindra N Dhir; Bernard H Shapiro
Prevention of latently expressed CYP2C11, CYP3A2, and growth hormone defects in neonatally monosodium glutamate-treated male rats by the N-methyl-D-aspartate receptor antagonist dizocilpine maleate.
The Journal of pharmacology and experimental therapeutics 2002;302(2):490-6.
2002: Ravindra N Dhir; Wojciech Dworakowski; Bernard H Shapiro
Middle-age alterations in the sexually dimorphic plasma growth hormone profiles: involvement of growth hormone-releasing factor and effects on cytochrome p450 expression.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(2):141-7.
2001: Arun K Agrawal; Bernard H Shapiro
Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat.
Molecular and cellular endocrinology 2001;173(1-2):167-81.
2001: M C Garcia; Chellappagounder Thangavel; Bernard H Shapiro
Epidermal growth factor regulation of female-dependent CYP2A1 and CYP2C12 in primary rat hepatocyte culture.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(2):111-20.
2001: NA Pampori; Arun K Agrawal; Bernard H Shapiro
Infusion of gender-dependent plasma growth hormone profiles into intact rats: effects of subcutaneous, intraperitoneal, and intravenous routes of rat and human growth hormone on endogenous circulating growth hormone profiles and expression of sexually dimorphic hepatic cyp isoforms.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(1):8-16.
2000: NA Pampori; Bernard H Shapiro
Nominal growth hormone pulses in otherwise normal masculine plasma profiles induce intron retention of overexpressed hepatic CYP2C11 with associated nuclear splicing deficiency.
Endocrinology 2000;141(11):4100-6.
2000: Arun K Agrawal; Bernard H Shapiro
Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s.
The Journal of pharmacology and experimental therapeutics 2000;293(3):1027-33.
2000: Arun K Agrawal; Bernard H Shapiro
Differential expression of gender-dependent hepatic isoforms of cytochrome P-450 by pulse signals in the circulating masculine episodic growth hormone profile of the rat.
The Journal of pharmacology and experimental therapeutics 2000;292(1):228-37.
1999: NA Pampori; Bernard H Shapiro
Gender differences in the responsiveness of the sex-dependent isoforms of hepatic P450 to the feminine plasma growth hormone profile.
Endocrinology 1999;140(3):1245-54.
1998: Mahesh C Sharma; Arun K Agrawal; Meena R Sharma; Bernard H Shapiro
Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression.
Biochemical pharmacology 1998;56(9):1251-8.
1998: Mahesh C Sharma; Meena R Sharma; Bernard H Shapiro
A comparison of cytochrome P450-dependent testosterone 2alpha-hydroxylase in rat (P4502C11) and mouse (P4502alpha).
Pharmacology 1998;56(2):71-9.
1997: Arun K Agrawal; Bernard H Shapiro
Gender, age and dose effects of neonatally administered aspartate on the sexually dimorphic plasma growth hormone profiles regulating expression of the rat sex-dependent hepatic CYP isoforms.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(11):1249-56.
1996: A K Agrawal; Bernard H Shapiro
Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital.
The Journal of pharmacology and experimental therapeutics 1996;279(2):991-9.
1996: N A Pampori; Bernard H Shapiro
Feminization of hepatic cytochrome P450s by nominal levels of growth hormone in the feminine plasma profile.
Molecular pharmacology 1996;50(5):1148-56.
1996: Mahesh C Sharma; Meena R Sharma; Seong-Joo Jeong; Bernard H Shapiro
Purification and characterization of constituent androstenedione 15 alpha-hydroxylase (cytochrome P450(15 alpha AD)) from mouse liver. Sex- and tissue-dependent expression.
Biochemical pharmacology 1996;52(6):901-10.
1996: J H Wani; A K Agrawal; Bernard H Shapiro
Neonatal phenobarbital-induced persistent alterations in plasma testosterone profiles and testicular function.
Toxicology and applied pharmacology 1996;137(2):295-300.
1996: A K Agrawal; Bernard H Shapiro
Phenobarbital induction of hepatic CYP2B1 and CYP2B2: pretranscriptional and post-transcriptional effects of gender, adult age, and phenobarbital dose.
Molecular pharmacology 1996;49(3):523-31.
1995: Mahesh C Sharma; Seong-Joo Jeong; Meena R Sharma; Bernard H Shapiro
Simulataneous isolation of NADPH-cytochrome P-450 reductase and cytochrome P-450 using tentacle ion-exchange chromatography and interspecies comparison of the reductase activity.
Pharmacology 1995;51(5):331-40.
1995: D J Waxman; P A Ram; N A Pampori; Bernard H Shapiro
Growth hormone regulation of male-specific rat liver P450s 2A2 and 3A2: induction by intermittent growth hormone pulses in male but not female rats rendered growth hormone deficient by neonatal monosodium glutamate.
Molecular pharmacology 1995;48(5):790-7.
1995: N A Pampori; M K Pampori; Bernard H Shapiro
Dilution of the chemiluminescence reagents reduces the background noise on western blots.
BioTechniques 1995;18(4):588-90.
1995: A K Agrawal; N A Pampori; Bernard H Shapiro
Neonatal phenobarbital-induced defects in age- and sex-specific growth hormone profiles regulating monooxygenases.
The American journal of physiology 1995;268(3 Pt 1):E439-45.
1995: Mahesh C Sharma; Bernard H Shapiro
Purification and characterization of constituent testosterone 2 alpha-hydroxylase (cytochrome P450(2)alpha) from mouse liver.
Archives of biochemistry and biophysics 1995;316(1):478-84.
1995: Bernard H Shapiro; A K Agrawal; N A Pampori
Gender differences in drug metabolism regulated by growth hormone.
The international journal of biochemistry & cell biology 1995;27(1):9-20.
1995: A K Agrawal; N A Pampori; Bernard H Shapiro
Thin-layer chromatographic separation of regioselective and stereospecific androgen metabolites.
Analytical biochemistry 1995;224(1):455-7.
1994: N A Pampori; Bernard H Shapiro
Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate.
The Journal of pharmacology and experimental therapeutics 1994;271(2):1067-73.
1994: N A Pampori; Bernard H Shapiro
Testicular regulation of sexual dimorphisms in the ultradian profiles of circulating growth hormone in the chicken.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(3):313-8.
1994: Bernard H Shapiro; N A Pampori; D P Lapenson; D J Waxman
Growth hormone-dependent and -independent sexually dimorphic regulation of phenobarbital-induced hepatic cytochromes P450 2B1 and 2B2.
Archives of biochemistry and biophysics 1994;312(1):234-9.
1994: N A Pampori; Bernard H Shapiro
Subnormal concentrations in the feminine profile of circulating growth hormone enhance expression of female-specific CYP2C12.
Biochemical pharmacology 1994;47(11):1999-2004.
1994: N A Pampori; Bernard H Shapiro
Effects of neonatally administered monosodium glutamate on the sexually dimorphic profiles of circulating growth hormone regulating murine hepatic monooxygenases.
Biochemical pharmacology 1994;47(7):1221-9.
1993: N A Pampori; Bernard H Shapiro
Sexual dimorphism in avian hepatic monooxygenases.
Biochemical pharmacology 1993;46(5):885-90.
1993: Bernard H Shapiro; N A Pampori; P A Ram; D J Waxman
Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate.
The Journal of pharmacology and experimental therapeutics 1993;265(2):979-84.
1992: G O Babalola; Bernard H Shapiro
Changes in the expression of cytochrome P450c17 associated with ovarian cystic follicles. An immunocytochemical and enzymatic analysis of porcine ovaries.
The Journal of steroid biochemistry and molecular biology 1992;42(6):581-7.
1991: J N MacLeod; N A Pampori; Bernard H Shapiro
Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice.
The Journal of endocrinology 1991;131(3):395-9.
1991: D J Waxman; N A Pampori; P A Ram; A K Agrawal; Bernard H Shapiro
Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6868-72.
1991: N A Pampori; A K Agrawal; D J Waxman; Bernard H Shapiro
Differential effects of neonatally administered glutamate on the ultradian pattern of circulating growth hormone regulating expression of sex-dependent forms of cytochrome P450.
Biochemical pharmacology 1991;41(9):1299-309.
1991: A K Agrawal; N A Pampori; Bernard H Shapiro
Sex- and dose-dependent effects of neonatally administered aspartate on the ultradian patterns of circulating growth hormone regulating hexobarbital metabolism and action.
Toxicology and applied pharmacology 1991;108(1):96-106.
1991: N A Pampori; A K Agrawal; Bernard H Shapiro
Renaturalizing the sexually dimorphic profiles of circulating growth hormone in hypophysectomized rats.
Acta endocrinologica 1991;124(3):283-9.
1991: Bernard H Shapiro; Milad S Bitar
Developmental levels and androgen responsiveness of hepatic mono-oxygenases of male rats perinatally exposed to maternally administered cimetidine.
Toxicology letters 1991;55(1):85-98.
1991: Milad S Bitar; M Ota; M Linnoila; Bernard H Shapiro
Modification of gonadectomy-induced increases in brain monoamine metabolism by steroid hormones in male and female rats.
Psychoneuroendocrinology 1991;16(6):547-57.
1990: G O Babalola; Bernard H Shapiro
Sex steroid changes in porcine cystic ovarian disease.
Steroids 1990;55(7):319-24.
1990: D J Waxman; J J Morrissey; J N MacLeod; Bernard H Shapiro
Depletion of serum growth hormone in adult female rats by neonatal monosodium glutamate treatment without loss of female-specific hepatic enzymes P450 2d (IIC12) and steroid 5 alpha-reductase.
Endocrinology 1990;126(2):712-20.
1989: Bernard H Shapiro; J N MacLeod; N A Pampori; J J Morrissey; D P Lapenson; D J Waxman
Signalling elements in the ultradian rhythm of circulating growth hormone regulating expression of sex-dependent forms of hepatic cytochrome P450.
Endocrinology 1989;125(6):2935-44.
1989: J N MacLeod; Bernard H Shapiro
Growth hormone regulation of hepatic drug-metabolizing enzymes in the mouse.
Biochemical pharmacology 1989;38(10):1673-7.
1989: Bernard H Shapiro; T M Niedermeyer; G O Babalola
Serum androgen levels in senescent Cr1:CD-1 (ICR)BR mice: effects of castration and testosterone treatment.
Journal of gerontology 1989;44(1):B15-9.
1988: Bernard H Shapiro; S A Hirst; G O Babalola; Milad S Bitar
Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine.
Toxicology letters 1988;44(3):315-29.
1988: J N MacLeod; Bernard H Shapiro
Repetitive blood sampling in unrestrained and unstressed mice using a chronic indwelling right atrial catheterization apparatus.
Laboratory animal science 1988;38(5):603-8.
1988: G O Babalola; Bernard H Shapiro
Correlation of follicular steroid hormone profiles with ovarian cyclicity in sows.
Journal of reproduction and fertility 1988;84(1):79-87.
1988: T M Niedermeyer; Bernard H Shapiro
Selective androgen insensitivity of hepatic drug-metabolizing enzymes in senescent mice.
Biochemical pharmacology 1988;37(2):241-6.
1987: Bernard H Shapiro; G O Babalola
Developmental profile of serum androgens and estrous cyclicity of male and female rats exposed, perinatally, to maternally administered phenytoin.
Toxicology letters 1987;39(2-3):165-75.
1987: Milad S Bitar; Bernard H Shapiro
Unresponsiveness of female rat hepatic monooxygenases to physiological levels of testosterone.
Biochemical pharmacology 1987;36(20):3543-5.
1987: J N Macleod; M P Sorensen; Bernard H Shapiro
Strain independent elevation of hepatic mono-oxygenase enzymes in female mice.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(9):1095-102.
1987: Milad S Bitar; Bernard H Shapiro
Aberration of heme and hemoprotein in aged female rats.
Mechanisms of ageing and development 1987;38(2):189-97.
1986: Bernard H Shapiro; R C Albucher; J N MacLeod; Milad S Bitar
Normal levels of hepatic drug-metabolizing enzymes in neonatally induced, growth hormone-deficient adult male and female rats.
Drug metabolism and disposition: the biological fate of chemicals 1986;14(5):585-9.