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Frank Sharp

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Michelle L Apperson; Glen C Jickling; Mark A Agius; Bradley P Ander; Boryana S Stamova; Yingfang Tian; Frank R Sharp
Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study.
Joan Gunther; Pieter J Hoekstra; Glen Jickling; Lisa Lit; Da Liu; Brad Ander; Netty Bos-Veneman; Blythe A Corbett; Boryana S Stamova; Yingfang Tian; Xinhua Zhan; Frank R Sharp
Catecholamine-related gene expression in blood correlates with tic severity in tourette syndrome.
Lisa Lit; Frank R Sharp; A D Sossong; Boryana S Stamova; B P Ander; K Bertoglio; Robert L Hendren
Gene expression in blood is associated with risperidone response in children with autism spectrum disorders.

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2013: Michelle L Apperson; Glen C Jickling; Mark A Agius; Bradley P Ander; Boryana S Stamova; Yingfang Tian; Frank R Sharp
Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study.
Journal of neuroimmunology 2013;257(1-2):90-6.
2012: Joan Gunther; Pieter J Hoekstra; Glen Jickling; Lisa Lit; Da Liu; Brad Ander; Netty Bos-Veneman; Blythe A Corbett; Boryana S Stamova; Yingfang Tian; Xinhua Zhan; Frank R Sharp
Catecholamine-related gene expression in blood correlates with tic severity in tourette syndrome.
Psychiatry research 2012;200(2-3):593-601.
2012: Lisa Lit; Frank R Sharp; A D Sossong; Boryana S Stamova; B P Ander; K Bertoglio; Robert L Hendren
Gene expression in blood is associated with risperidone response in children with autism spectrum disorders.
The pharmacogenomics journal 2012;12(5):368-71.
2012: Glen C Jickling; Dazhi Liu; Bradley P Ander; Shara-Mae Sison; Boryana S Stamova; Piero Verro; Xinhua Zhan; Frank R Sharp
Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location.
Stroke; a journal of cerebral circulation 2012;43(8):2036-41.
2012: Yingfang Tian; Piero Verro; Xinhua Zhan; Boryana S Stamova; Bradley P Ander; Joseph P Broderick; Cheryl Bushnell; Ryan R Davis; David L Dawson; Nasim Hedayati; Edward Jauch; Glen C Jickling; Jane Khoury; Dazhi Liu; Arthur Pancioli; William C Pevec; Frank R Sharp
Effects of gender on gene expression in the blood of ischemic stroke patients.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(5):780-91.
2012: Yingfang Tian; Renee J Turner; Piero Verro; Huichun Xu; Xinhua Zhan; Boryana S Stamova; Bradley P Ander; Joseph P Broderick; Cheryl Bushnell; Ryan R Davis; David L Dawson; Nasim Hedayati; Edward Jauch; Glen C Jickling; Jane Khoury; Dazhi Liu; Arthur Pancioli; William C Pevec; Frank R Sharp
Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls.
Gender medicine 2012;9(2):68-75.e3.
2012: Glen C Jickling; S Claiborne Johnston; Dazhi Liu; Shara-Mae Sison; Boryana S Stamova; Yingfang Tian; Piero Verro; Xinhua Zhan; Bradley P Ander; Frank R Sharp
Ischemic transient neurological events identified by immune response to cerebral ischemia.
Stroke; a journal of cerebral circulation 2012;43(4):1006-12.
2012: Da-Zhi Liu; Bradley P Ander; Ryan R Davis; Glen C Jickling; Boryana S Stamova; Yingfang Tian; Frank R Sharp
Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells.
Gene 2012;495(2):120-7.
2012: Boryana S Stamova; Yingfang Tian; Piero Verro; Xinhua Zhan; Bradley P Ander; Joseph P Broderick; Cheryl Bushnell; David L Dawson; Nasim Hedayati; Edward Jauch; Glen Jickling; Dazhi Liu; Arthur Pancioli; Vihar Patel; William C Pevec; Frank R Sharp
The X-chromosome has a different pattern of gene expression in women compared with men with ischemic stroke.
Stroke; a journal of cerebral circulation 2012;43(2):326-34.
2012: Yingfang Tian; Boryana S Stamova; Bradley P Ander; Netty G P Bos-Veneman; Blythe A Corbett; Joan R Gunther; Pieter J Hoekstra; Glen C Jickling; Julie Schweitzer; Frank R Sharp
Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study.
BMC medical genomics 2012;5():49.
2011: X Zhan; B P Ander; C Bushnell; G C Jickling; S Claiborne Johnston; M Mesias; Boryana S Stamova; Y Tian; R J Turner; Piero Verro; Huichun Xu; Frank R Sharp
Transient ischemic attacks characterized by RNA profiles in blood.
Neurology 2011;77(19):1718-24.
2011: Glen C Jickling; S Claiborne Johnston; Dazhi Liu; Boryana S Stamova; Yingfang Tian; Piero Verro; Huichun Xu; Xinhua Zhan; Bradley P Ander; Frank R Sharp
Profiles of lacunar and nonlacunar stroke.
Annals of neurology 2011;70(3):477-85.
2011: Gregory J del Zoppo; Wolf-Dieter Heiss; Frank R Sharp; Gregory W Albers
Heterogeneity in the penumbra.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(9):1836-51.
2011: Frank R Sharp; Boryana S Stamova; Yingfang Tian; Xinhua Zhan; Bradley P Ander; Christopher Cox; Glen C Jickling; Beth Kuczynski; Dazhi Liu
RNA expression profiles from blood for the diagnosis of stroke and its causes.
Journal of child neurology 2011;26(9):1131-6.
2011: Glen C Jickling; Frank R Sharp
Blood biomarkers of ischemic stroke.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2011;8(3):349-60.
2011: Frank R Sharp; Boryana S Stamova; Yingfang Tian; Xinhua Zhan; Christopher D Cox; Glen C Jickling; Beth Kuczynski; DaZhi Liu; Bradley P Ander
Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(7):1513-31.
2011: Xinhua Zhan; Beth Kuczynski; Frank R Sharp
Post stroke intervention: is the window widening?
Neuropharmacology 2011;60(6):1000-2.
2011: Yingfang Tian; Joan R Gunther; Isaac H Liao; Dazhi Liu; Bradley P Ander; Boryana S Stamova; Lisa Lit; Glen C Jickling; Huichun Xu; Xinhua Zhan; Frank R Sharp
GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study.
Brain research 2011;1381():228-36.
2011: Edward A Neuwelt; Björn Bauer; Christoph Fahlke; Gert Fricker; costantino iadecola; Damir Janigro; Luc Leybaert; Zoltán Molnár; Martha E O'Donnell; John T Povlishock; Norman R Saunders; Frank R Sharp; Danica Stanimirovic; Ryan J Watts; Lester R Drewes
Engaging neuroscience to advance translational research in brain barrier biology.
Nature reviews. Neuroscience 2011;12(3):169-82.
2011: Huichun Xu; Aigang Lu; Frank R Sharp
Regional genome transcriptional response of adult mouse brain to hypoxia.
BMC genomics 2011;12():499.
2011: Da-Zhi Liu; Frank R Sharp
The dual role of SRC kinases in intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2011;111():77-81.
2011: Yingfang Tian; Isaac H Liao; Xinhua Zhan; Joan R Gunther; Bradley P Ander; Dazhi Liu; Lisa Lit; Glen C Jickling; Blythe A Corbett; Netty G P Bos-Veneman; Pieter J Hoekstra; Frank R Sharp
Exon expression and alternatively spliced genes in Tourette Syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(1):72-8.
2011: Yingfang Tian; Michelle L Apperson; Bradley P Ander; Dazhi Liu; Boryana S Stomova; Glen C Jickling; Richelle Enriquez; Mark A Agius; Frank R Sharp
Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjects.
Journal of neuroimmunology 2011;230(1-2):124-9.
2011: Boryana S Stamova; Peter G Green; Yingfang Tian; Irva Hertz-Picciotto; Isaac N Pessah; Robin Hansen; Xiaowei Yang; Jennifer Teng; Jeffrey P Gregg; Paul Ashwood; Judith A van de Water; Frank R Sharp
Correlations between gene expression and mercury levels in blood of boys with and without autism.
Neurotoxicity research 2011;19(1):31-48.
2011: Yingfang Tian; Peter G Green; Boryana S Stamova; Irva Hertz-Picciotto; Isaac N Pessah; Robin Hansen; Xiaowei Yang; Jeffrey P Gregg; Paul Ashwood; Glen Jickling; Judith A van de Water; Frank R Sharp
Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls.
Neurotoxicity research 2011;19(1):1-13.
2010: Isaac H Liao; Blythe A Corbett; Donald L Gilbert; Silvia A Bunge; Frank R Sharp
Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome.
Pharmacogenomics 2010;11(12):1733-41.
2010: Huichun Xu; Boryana Stamova; Glen Jickling; Yingfang Tian; Xinhua Zhan; Bradley P Ander; Dazhi Liu; Renée Turner; Jonathan Rosand; Larry B Goldstein; Karen L Furie; Piero Verro; S Claiborne Johnston; Frank R Sharp; Charles DeCarli
Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain.
Stroke; a journal of cerebral circulation 2010;41(12):2744-9.
2010: Glen C Jickling; Huichun Xu; Boryana Stamova; Bradley P Ander; Xinhua Zhan; Yingfang Tian; Dazhi Liu; Renée J Turner; Matthew Mesias; Piero Verro; Jane Khoury; Edward Jauch; Arthur Pancioli; Joseph P Broderick; Frank R Sharp
Signatures of cardioembolic and large-vessel ischemic stroke.
Annals of neurology 2010;68(5):681-92.
2010: Boryana Stamova; Huichun Xu; Glen Jickling; Cheryl Bushnell; Yingfang Tian; Bradley P Ander; Xinhua Zhan; Dazhi Liu; Renee Turner; Peter Adamczyk; Jane C Khoury; Arthur Pancioli; Edward Jauch; Joseph P Broderick; Frank R Sharp
Gene expression profiling of blood for the prediction of ischemic stroke.
Stroke; a journal of cerebral circulation 2010;41(10):2171-7.
2010: Isaac H Liao; Frank R Sharp
Tourette syndrome: gene expression as a tool to discover drug targets.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2010;7(3):302-6.
2010: Da-Zhi Liu; Bradley P Ander; Huichun Xu; Yan Shen; Pali Kaur; Wenbin Deng; Frank R Sharp
Blood-brain barrier breakdown and repair by Src after thrombin-induced injury.
Annals of neurology 2010;67(4):526-33.
2010: Xinhua Zhan; Bradley P Ander; Isaac H Liao; James E Hansen; Chester Kim; Douglas Clements; Richard H Weisbart; Robert N Nishimura; Frank R Sharp
Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 2010;41(3):538-43.
2010: Da-Zhi Liu; Bradley P Ander; Frank R Sharp
Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of central nervous system diseases.
Neurobiology of disease 2010;37(3):549-57.
2010: Glen C Jickling; Xinhua Zhan; Bradley P Ander; Renée J Turner; Boryana Stamova; Huichun Xu; Yingfang Tian; Dazhi Liu; Ryan R Davis; Paul A Lapchak; Frank R Sharp
Genome response to tissue plasminogen activator in experimental ischemic stroke.
BMC genomics 2010;11():254.
2010: Xinhua Zhan; Bradley P Ander; Glen Jickling; Renée Turner; Boryana S Stamova; Huichun Xu; Dazhi Liu; Ryan R Davis; Frank R Sharp
Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):110-8.
2010: Da-Zhi Liu; Yingfang Tian; Bradley P Ander; Huichun Xu; Boryana S Stamova; Xinhua Zhan; Renee J Turner; Glen Jickling; Frank R Sharp
Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):92-101.
2009: Robert L Hendren; Kiah Bertoglio; Paul Ashwood; Frank R Sharp
Mechanistic biomarkers for autism treatment.
Medical hypotheses 2009;73(6):950-4.
2009: Lisa Lit; Frank R Sharp; Michelle Apperson; D Z Liu; W L Walker; I Liao; Huichun Xu; B P Ander; Brenda Wong
Corticosteroid effects on blood gene expression in Duchenne muscular dystrophy.
The pharmacogenomics journal 2009;9(6):411-8.
2009: Aigang Lu; Joseph F Clark; Ruiqiong Ran; Gail Pyne-Geithman; Kenneth R Wagner; David E Millhorn; Frank R Sharp
Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent.
Neurological research 2009;31(5):545-9.
2009: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Mechanical reperfusion is associated with post-ischemic hemorrhage in rat brain.
Experimental neurology 2009;216(2):407-12.
2009: Brenda Wong; Donald L Gilbert; Wynn L Walker; Isaac H Liao; Lisa Lit; Boryana Stamova; Glen Jickling; Michelle Apperson; Frank R Sharp
Gene expression in blood of subjects with Duchenne muscular dystrophy.
Neurogenetics 2009;10(2):117-25.
2009: Boryana S Stamova; Michelle Apperson; Wynn L Walker; Yingfang Tian; Huichun Xu; Peter Adamczy; Xinhua Zhan; Da-Zhi Liu; Bradley P Ander; Isaac H Liao; Jeffrey P Gregg; Renee J Turner; Glen Jickling; Lisa Lit; Frank R Sharp
Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood.
BMC medical genomics 2009;2():49.
2009: Amanda M Enstrom; Lisa Lit; Charity E Onore; Jeffrey P Gregg; Robin Hansen; Isaac N Pessah; Irva Hertz-Picciotto; Judith A van de Water; Frank R Sharp; Paul Ashwood
Altered gene expression and function of peripheral blood natural killer cells in children with autism.
Brain, behavior, and immunity 2009;23(1):124-33.
2009: Lisa Lit; Amanda Enstrom; Frank R Sharp; Donald L Gilbert
Age-related gene expression in Tourette syndrome.
Journal of psychiatric research 2009;43(3):319-30.
2008: Xinhua Zhan; Charles Kim; Frank R Sharp
Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein.
Brain research 2008;1234():183-97.
2008: Huichun Xu; Yang Tang; Da-Zhi Liu; Ruiqiong Ran; Bradley P Ander; Michelle Apperson; Xin She Liu; Jane C Khoury; Jeffrey P Gregg; Arthur Pancioli; Edward Jauch; Kenneth R Wagner; Piero Verro; Joseph P Broderick; Frank R Sharp
Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(7):1320-8.
2008: Da-Zhi Liu; Xi-Yuan Cheng; Bradley P Ander; Huichun Xu; Ryan R Davis; Jeffrey P Gregg; Frank R Sharp
Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons.
Neurobiology of disease 2008;30(2):201-11.
2008: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Ruiqiong Ran; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Reperfusion activates metalloproteinases that contribute to neurovascular injury.
Experimental neurology 2008;210(2):549-59.
2008: Frank R Sharp; D Z Liu; X Zhan; B P Ander
Intracerebral hemorrhage injury mechanisms: glutamate neurotoxicity, thrombin, and Src.
Acta neurochirurgica. Supplement 2008;105():43-6.
2008: Wynn L Walker; Isaac H Liao; Donald L Gilbert; Brenda Wong; Katherine S Pollard; Charles E McCulloch; Lisa Lit; Frank R Sharp
Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients.
BMC genomics 2008;9():494.
2008: Scott H Robbins; Thierry Walzer; Doulaye Dembélé; Christelle Thibault; Axel Defays; Gilles Bessou; Huichun Xu; Eric Vivier; MacLean Sellars; Philippe Pierre; Frank R Sharp; Susan Chan; Philippe Kastner; Marc Dalod
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling.
Genome biology 2008;9(1):R17.
2008: Jeffrey P Gregg; Lisa Lit; Colin A Baron; Irva Hertz-Picciotto; Wynn Walker; Ryan A Davis; Lisa A Croen; Sally Ozonoff; Robin Hansen; Isaac N Pessah; Frank R Sharp
Gene expression changes in children with autism.
Genomics 2008;91(1):22-9.
2007: Ruiqiong Ran; Ruiqin Pan; Aigang Lu; Huichun Xu; Ryan R Davis; Frank R Sharp
A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis.
Molecular and cellular neurosciences 2007;36(3):392-407.
2007: Lisa Lit; Donald L Gilbert; Wynn Walker; Frank R Sharp
A subgroup of Tourette's patients overexpress specific natural killer cell genes in blood: a preliminary report.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):958-63.
2007: Frank R Sharp; Robert L Hendren
Psychosis: atypical limbic epilepsy versus limbic hyperexcitability with onset at puberty?
Epilepsy & behavior : E&B 2007;10(4):515-20.
2007: Timothy D Ardizzone; Xinhua Zhan; Brad P Ander; Frank R Sharp
SRC kinase inhibition improves acute outcomes after experimental intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2007;38(5):1621-5.
2007: Blythe A Corbett; A B Kantor; H Schulman; W L Walker; Lisa Lit; Paul Ashwood; David Rocke; Frank R Sharp
A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins.
Molecular psychiatry 2007;12(3):292-306.
2007: Frank R Sharp; Huichun Xu; Lisa Lit; Wynn Walker; Joseph D Pinter; Michelle Apperson; Piero Verro
Genomic profiles of stroke in blood.
Stroke; a journal of cerebral circulation 2007;38(2 Suppl):691-3.
2006: Frank R Sharp; Huichun Xu; Lisa Lit; Wynn Walker; Michelle Apperson; Donald L Gilbert; Tracy A Glauser; Brenda Wong; Andrew D Hershey; Da-Zhi Liu; Joseph D Pinter; Xinhua Zhan; Xinshe Liu; Ruiqiong Ran
The future of genomic profiling of neurological diseases using blood.
Archives of neurology 2006;63(11):1529-36.
2006: Laurel M Pritchard; Aaron D Logue; Benjamin C Taylor; Rebecca Ahlbrand; Jeffrey Welge; Yang Tang; Frank R Sharp; Neil M Richtand
Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty.
Brain research bulletin 2006;70(4-6):296-303.
2006: Frank R Sharp; Lisa Lit; Huichun Xu; Michelle Apperson; Wynn Walker; Brenda Wong; Donald L Gilbert; Andrew D Hershey; Tracy A Glauser
Genomics of brain and blood: progress and pitfalls.
Epilepsia 2006;47(10):1603-7.
2006: Joseph F Clark; Frank R Sharp
Bilirubin oxidation products (BOXes) and their role in cerebral vasospasm after subarachnoid hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(10):1223-33.
2006: Faisal Adhami; Guanghong Liao; Yury M Morozov; Aryn Schloemer; Vincent J Schmithorst; John N Lorenz; R Scott Dunn; Charles V Vorhees; MARSHA WILLS-KARP; Jay L Degen; Roger J Davis; Noboru Mizushima; Pasko Rakic; Bernard Dardzinski; Scott K Holland; Frank R Sharp; Chia-Yi Kuan
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.
The American journal of pathology 2006;169(2):566-83.
2006: Yang Tang; Huichun Xu; XinLi Du; Lisa Lit; Wynn Walker; Aigang Lu; Ruiqiong Ran; Jeffrey P Gregg; Melinda Reilly; Art Pancioli; Jane C Khoury; Laura Sauerbeck; Janice Carrozzella; Judith Spilker; Joseph Clark; Kenneth R Wagner; Edward Jauch; Dongwoo J Chang; Piero Verro; Joseph P Broderick; Frank R Sharp
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(8):1089-102.
2006: Jon Dickerson; Frank R Sharp
Atypical antipsychotics and a Src kinase inhibitor (PP1) prevent cortical injury produced by the psychomimetic, noncompetitive NMDA receptor antagonist MK-801.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(7):1420-30.
2006: Zinaida S Vexler; Frank R Sharp; Giora Z Feuerstein; Stephen Ashwal; Marianne Thoresen; Jerome Y Yager; Donna M Ferriero
Translational stroke research in the developing brain.
Pediatric neurology 2006;34(6):459-63.
2006: Xinli Du; Yang Tang; Huichun Xu; Lisa Lit; Wynn Walker; Paul Ashwood; Jeffrey P Gregg; Frank R Sharp
Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome.
Genomics 2006;87(6):693-703.
2006: Aigang Lu; Yang Tang; Ruiqiong Ran; Timothy L Ardizzone; Kenneth R Wagner; Frank R Sharp
Brain genomics of intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(2):230-52.
2005: Robert N Nishimura; Frank R Sharp
Heat shock proteins and neuromuscular disease.
Muscle & nerve 2005;32(6):693-709.
2005: Dongsheng Zhang; Lu Zhang; Yang Tang; Qi Zhang; Danwen Lou; Frank R Sharp; Jianhua Zhang; Mingli Xu
Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(8):1443-54.
2005: Ruiqiong Ran; Huichun Xu; Aigang Lu; Myriam Bernaudin; Frank R Sharp
Hypoxia preconditioning in the brain.
Developmental neuroscience 2005;27(2-4):87-92.
2005: Yang Tang; Donald L Gilbert; Tracy A Glauser; Andrew D Hershey; Frank R Sharp
Blood gene expression profiling of neurologic diseases: a pilot microarray study.
Archives of neurology 2005;62(2):210-5.
2004: Yang Tang; Aigang Lu; Ruiqiong Ran; Bruce Aronow; Elizabeth K Schorry; Robert J Hopkin; Donald L Gilbert; Tracy A Glauser; Andrew D Hershey; Neil W Richtand; Michael D Privitera; Arif Dalvi; Alok Sahay; Jerzy P Szaflarski; David M Ficker; Nancy Ratner; Frank R Sharp
Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1.
Brain research. Molecular brain research 2004;132(2):155-67.
2004: Todd F Glass; Brandi Reeves; Frank R Sharp
The impact of excitotoxic blockade on the evolution of injury following combined mechanical and hypoxic insults in primary rat neuronal culture.
Neurobiology of disease 2004;17(3):378-84.
2004: Kevin Carter; Jon Dickerson; Darryle D Schoepp; Melinda Reilly; Nicole Herring; Jon Williams; Floyd R Sallee; James W Sharp; Frank R Sharp
The mGlu2/3 receptor agonist LY379268 injected into cortex or thalamus decreases neuronal injury in retrosplenial cortex produced by NMDA receptor antagonist MK-801: possible implications for psychosis.
Neuropharmacology 2004;47(8):1135-45.
2004: Yang Tang; Mark B Schapiro; David Neal Franz; Bonnie J Patterson; Francis J Hickey; Elizabeth K Schorry; Robert J Hopkin; Matthew Wylie; Tina Narayan; Tracy A Glauser; Donald L Gilbert; Andrew D Hershey; Frank R Sharp
Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and Down's syndrome.
Annals of neurology 2004;56(6):808-14.
2004: Chia-Yi Kuan; Aryn Schloemer; Aigang Lu; Kevin A Burns; Wei-Lan Weng; Michael T Williams; Kenneth I Strauss; Charles V Vorhees; Richard A Flavell; Roger J Davis; Frank R Sharp; Pasko Rakic
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(47):10763-72.
2004: Andrew D Hershey; Yang Tang; Scott W Powers; Marielle A Kabbouche; Donald L Gilbert; Tracy A Glauser; Frank R Sharp
Genomic abnormalities in patients with migraine and chronic migraine: preliminary blood gene expression suggests platelet abnormalities.
Headache 2004;44(10):994-1004.
2004: Philip R Weinstein; Shwuhuey Hong; Frank R Sharp
Molecular identification of the ischemic penumbra.
Stroke; a journal of cerebral circulation 2004;35(11 Suppl 1):2666-70.
2004: Timothy D Ardizzone; Aigang Lu; Kenneth R Wagner; Yang Tang; Ruiqiong Ran; Frank R Sharp
Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat.
Stroke; a journal of cerebral circulation 2004;35(11):2587-91.
2004: Young S Kim; Jari Honkaniemi; Frank R Sharp; Martin G Täuber
Expression of proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta in the brain during experimental group B streptococcal meningitis.
Brain research. Molecular brain research 2004;128(1):95-102.
2004: Toshihiro Yamauchi; Yong Lin; Frank R Sharp; Linda J Noble-Haeusslein
Hemin induces heme oxygenase-1 in spinal cord vasculature and attenuates barrier disruption and neutrophil infiltration in the injured murine spinal cord.
Journal of neurotrauma 2004;21(8):1017-30.
2004: Ruiqiong Ran; Aigang Lu; Lu Zhang; Yang Tang; Hongyan Zhu; Huichun Xu; Yuxin Feng; Chun Han; Guoping Zhou; Alan Rigby; Frank R Sharp
Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling.
Genes & development 2004;18(12):1466-81.
2004: Frank R Sharp; Myriam Bernaudin
HIF1 and oxygen sensing in the brain.
Nature reviews. Neuroscience 2004;5(6):437-48.
2004: Juha-Pekka Kalkkila; Frank R Sharp; Iivari Kärkkäinen; Melinda Reilly; Aigang Lu; Karen Solway; Matt Murrel; Jari Honkaniemi
Cloning and expression of short interspersed elements B1 and B2 in ischemic brain.
The European journal of neuroscience 2004;19(5):1199-206.
2004: Yang Tang; Tracy A Glauser; Donald L Gilbert; Andrew D Hershey; Michael D Privitera; David M Ficker; Jerzy P Szaflarski; Frank R Sharp
Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study.
Acta neurologica Scandinavica 2004;109(3):159-68.
2004: Frank R Sharp; Ruiqiong Ran; Aigang Lu; Yang Tang; Kenneth I Strauss; Todd Glass; Timothy D Ardizzone; Myriam Bernaudin
Hypoxic preconditioning protects against ischemic brain injury.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(1):26-35.
2004: Ruiqiong Ran; Guoping Zhou; Aigang Lu; Lu Zhang; Yang Tang; Alan Rigby; Frank R Sharp
Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival.
Cell stress & chaperones 2004;9(3):229-42.
2004: Myriam Bernaudin; Frank R Sharp
Methods to detect hypoxia-induced ischemic tolerance in the brain.
Methods in enzymology 2004;381():399-416.
2003: Aigang Lu; Yang Tang; Ruiqiong Ran; Joseph F Clark; Bruce Aronow; Frank R Sharp
Genomics of the periinfarction cortex after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(7):786-810.
2003: Yasuaki Kokubo; Jialing Liu; Sunita Rajdev; Takamasa Kayama; Frank R Sharp; Philip R Weinstein
Differential cerebral protein synthesis and heat shock protein 70 expression in the core and penumbra of rat brain after transient focal ischemia.
Neurosurgery 2003;53(1):186-90; discussion 190-1.
2003: Kenneth R Wagner; Frank R Sharp; Timothy D Ardizzone; Aigang Lu; Joseph F Clark
Heme and iron metabolism: role in cerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(6):629-52.
2003: Edward F Chang; Ronald J Wong; Hendrik J Vreman; Takuji Igarashi; Ethel Galo; Frank R Sharp; David K Stevenson; Linda J Noble-Haeusslein
Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(9):3689-96.
2003: Yang Tang; Alex Nee; Aigang Lu; Ruiqiong Ran; Frank R Sharp
Blood genomic expression profile for neuronal injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(3):310-9.
2003: Anthony Mancuso; nikita derugin; Kazushi Hara; Theresa A Marsh; Daniel Kong; Frank R Sharp; Philip R Weinstein
Cyclooxygenase-2 mRNA expression is associated with c-fos mRNA expression and transient water ADC reduction detected with diffusion MRI during acute focal ischemia in rats.
Brain research 2003;961(1):121-30.
2002: Myriam Bernaudin; Yang Tang; Melinda Reilly; Edwige Petit; Frank R Sharp
Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance.
The Journal of biological chemistry 2002;277(42):39728-38.
2002: Todd F Glass; Brandi Reeves; Frank R Sharp
Modeling both the mechanical and hypoxic features of traumatic brain injury in vitro in rats.
Neuroscience letters 2002;328(2):133-6.
2002: Guodong Cao; Wei Pei; Hailiang Ge; Qinhua Liang; Yumin Luo; Frank R Sharp; Aigang Lu; Ruiqiong Ran; Steven H Graham; Jun Chen
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(13):5423-31.
2002: Yang Tang; Aigang Lu; Bruce Aronow; Kenneth R Wagner; Frank R Sharp
Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia.
The European journal of neuroscience 2002;15(12):1937-52.
2002: Yasuaki Kokubo; Gerald B Matson; Jialing Liu; Anthony Mancuso; Takamasa Kayama; Frank R Sharp; Philip R Weinstein
Correlation between changes in apparent diffusion coefficient and induction of heat shock protein, cell-specific injury marker expression, and protein synthesis reduction on diffusion-weighted magnetic resonance images after temporary focal cerebral ischemia in rats.
Journal of neurosurgery 2002;96(6):1084-93.
2002: Aigang Lu; Ruiqiong Ran; Sophie Parmentier-Batteur; Alex Nee; Frank R Sharp
Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia.
Journal of neurochemistry 2002;81(2):355-64.
2002: Joseph F Clark; Melinda Reilly; Frank R Sharp
Oxidation of bilirubin produces compounds that cause prolonged vasospasm of rat cerebral vessels: a contributor to subarachnoid hemorrhage-induced vasospasm.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):472-8.
2002: Frank R Sharp; Jialing Liu; Ramon Bernabeu
Neurogenesis following brain ischemia.
Brain research. Developmental brain research 2002;134(1-2):23-30.
2002: Patricia Murphy; Anthony Sharp; Joseph Shin; Vitaliy Gavrilyuk; Cinzia Dello Russo; Guy Weinberg; Frank R Sharp; Aigang Lu; Michael T Heneka; Douglas L Feinstein
Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis.
Journal of neuroscience research 2002;67(4):461-70.
2002: Aigang Lu; Ruiqiong Ran; Joseph Clark; Melinda Reilly; Alex Nee; Frank R Sharp
17-beta-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(2):183-95.
2001: Yang Tang; Aigang Lu; Bruce Aronow; Frank R Sharp
Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease.
Annals of neurology 2001;50(6):699-707.
2001: Frank R Sharp; M Tomitaka; Myriam Bernaudin; S Tomitaka
Psychosis: pathological activation of limbic thalamocortical circuits by psychomimetics and schizophrenia?
Trends in neurosciences 2001;24(6):330-4.
2001: Jialing Liu; M Bartels; A Lu; Frank R Sharp
Microglia/macrophages proliferate in striatum and neocortex but not in hippocampus after brief global ischemia that produces ischemic tolerance in gerbil brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(4):361-73.
2001: Frank R Sharp; M Bergeron; Myriam Bernaudin
Hypoxia-inducible factor in brain.
Advances in experimental medicine and biology 2001;502():273-91.
2001: Frank R Sharp; Myriam Bernaudin; M Bartels; Kenneth R Wagner
Glial expression of heat shock proteins (HSPs) and oxygen-regulated proteins (ORPs).
Progress in brain research 2001;132():427-40.
2000: Anthony Mancuso; nikita derugin; Kazushi Hara; Frank R Sharp; Philip R Weinstein
Mild hypothermia decreases the incidence of transient ADC reduction detected with diffusion MRI and expression of c-fos and hsp70 mRNA during acute focal ischemia in rats.
Brain research 2000;887(1):34-45.
2000: Ramon Bernabeu; Frank R Sharp
NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(12):1669-80.
2000: Angelika Mautes; M Bergeron; Frank R Sharp; S Scott Panter; Martin R Weinzierl; K Guenther; Linda J Noble
Sustained induction of heme oxygenase-1 in the traumatized spinal cord.
Experimental neurology 2000;166(2):254-65.
2000: Jari Honkaniemi; J S Zhang; Frank M Longo; Frank R Sharp
Stress induces zinc finger immediate early genes in the rat adrenal gland.
Brain research 2000;877(2):203-8.
2000: B K Tolliver; M W Sganga; Frank R Sharp
Suppression of c-fos induction in the nucleus accumbens prevents acquisition but not expression of morphine-conditioned place preference.
The European journal of neuroscience 2000;12(9):3399-406.
2000: M Bergeron; J M Gidday; A Y Yu; Gregg L Semenza; Donna M Ferriero; Frank R Sharp
Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain.
Annals of neurology 2000;48(3):285-96.
2000: Jialing Liu; W Ying; S Massa; P J Duriez; Raymond Swanson; G G Poirier; Frank R Sharp
Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains.
Brain research. Molecular brain research 2000;80(1):7-16.
2000: Frank R Sharp; Aigang Lu; Yang Tang; David E Millhorn
Multiple molecular penumbras after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(7):1011-32.
2000: Joseph H Rapp; Xian Mang Pan; Frank R Sharp; D M Shah; G A Wille; P M Velez; Aaron Troyer; Randall T Higashida; David Saloner
Atheroemboli to the brain: size threshold for causing acute neuronal cell death.
Journal of vascular surgery 2000;32(1):68-76.
2000: Sunita Rajdev; K Hara; Y Kokubo; Ruben Mestril; W Dillmann; Philip R Weinstein; Frank R Sharp
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction.
Annals of neurology 2000;47(6):782-91.
2000: M Tomitaka; S Tomitaka; S Rajdev; Frank R Sharp
Fluoxetine prevents PCP- and MK801-induced HSP70 expression in injured limbic cortical neurons of rats.
Biological psychiatry 2000;47(9):836-41.
2000: S Tomitaka; M Tomitaka; B K Tolliver; Frank R Sharp
Bilateral blockade of NMDA receptors in anterior thalamus by dizocilpine (MK-801) injures pyramidal neurons in rat retrosplenial cortex.
The European journal of neuroscience 2000;12(4):1420-30.
2000: Sunita Rajdev; Frank R Sharp
Stress proteins as molecular markers of neurotoxicity.
Toxicologic pathology 2000;28(1):105-12.
2000: E Joelson; B Ruthrauff; F Ali; Neil Lindeman; Frank R Sharp
Multifocal dural enhancement associated with temporal arteritis.
Archives of neurology 2000;57(1):119-22.
1999: M Bergeron; A Y Yu; Karen Solway; Gregg L Semenza; Frank R Sharp
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain.
The European journal of neuroscience 1999;11(12):4159-70.
1999: Anthony Mancuso; nikita derugin; Y Ono; Kazushi Hara; Frank R Sharp; Philip R Weinstein
Transient MRI-detected water apparent diffusion coefficient reduction correlates with c-fos mRNA but not hsp70 mRNA induction during focal cerebral ischemia in rats.
Brain research 1999;839(1):7-22.
1999: Frank R Sharp; S M Massa; Raymond Swanson
Heat-shock protein protection.
Trends in neurosciences 1999;22(3):97-9.
1999: C P Turner; S Scott Panter; Frank R Sharp
Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood.
Brain research. Molecular brain research 1999;65(1):87-102.
1999: M Bergeron; Sydney Evans; Frank R Sharp; Cameron J Koch; E M Lord; Donna M Ferriero
Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia.
Neuroscience 1999;89(4):1357-66.
1999: J Honkaniemi; Frank R Sharp
Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures.
The European journal of neuroscience 1999;11(1):10-7.
1998: Sunita Rajdev; A S Fix; Frank R Sharp
Acute phencyclidine neurotoxicity in rat forebrain: induction of haem oxygenase-1 and attenuation by the antioxidant dimethylthiourea.
The European journal of neuroscience 1998;10(12):3840-52.
1998: K Hara; D L Kong; Frank R Sharp; Philip R Weinstein
Effect of selective inhibition of cyclooxygenase 2 on temporary focal cerebral ischemia in rats.
Neuroscience letters 1998;256(1):53-6.
1998: S Sato; Glenn T Gobbel; J Honkaniemi; Y Li; T Kondo; K Murakami; M Sato; Jean-Christophe Copin; Frank R Sharp; Pak H Chan
Decreased expression of bcl-2 and bcl-x mRNA coincides with apoptosis following intracerebral administration of 3-nitropropionic acid.
Brain research 1998;808(1):56-64.
1998: Frank R Sharp
Stress genes protect brain.
Annals of neurology 1998;44(4):581-3.
1998: Jialing Liu; Karen Solway; R O Messing; Frank R Sharp
Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(19):7768-78.
1998: Angelika Mautes; D H Kim; Frank R Sharp; S Scott Panter; M Sato; Nino Maida; M Bergeron; K Guenther; Linda J Noble
Induction of heme oxygenase-1 (HO-1) in the contused spinal cord of the rat.
Brain research 1998;795(1-2):17-24.
1998: K Hasegawa; Lawrence Litt; MT Espanol; Frank R Sharp; Pak H Chan
Expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices during NMDA-induced necrosis and apoptosis.
Brain research 1998;785(2):262-78.
1998: C P Turner; M Bergeron; P Matz; A Zegna; Linda J Noble; S Scott Panter; Frank R Sharp
Heme oxygenase-1 is induced in glia throughout brain by subarachnoid hemoglobin.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(3):257-73.
1998: M Bergeron; D M Ferriero; Frank R Sharp
Developmental expression of heme oxygenase-1 (HSP32) in rat brain: an immunocytochemical study.
Brain research. Developmental brain research 1998;105(2):181-94.
1998: Jeremy D Richmon; K Fukuda; Nino Maida; M Sato; M Bergeron; Frank R Sharp; S Scott Panter; Linda J Noble
Induction of heme oxygenase-1 after hyperosmotic opening of the blood-brain barrier.
Brain research 1998;780(1):108-18.
1997: B Bontempi; Frank R Sharp
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8596-612.
1997: M Bergeron; D M Ferriero; H J Vreman; D K Stevenson; Frank R Sharp
Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(6):647-58.
1997: J Honkaniemi; B A States; Philip R Weinstein; J Espinoza; Frank R Sharp
Expression of zinc finger immediate early genes in rat brain after permanent middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(6):636-46.
1997: J Q Lan; Jun Chen; Frank R Sharp; Roger P. Simon; Steven H Graham
Induction of heat-shock protein (HSP72) in the cingulate and retrosplenial cortex by drugs that antagonize the effects of excitatory amino acids.
Brain research. Molecular brain research 1997;46(1-2):297-302.
1997: K Hasegawa; Lawrence Litt; MT Espanol; George A Gregory; Frank R Sharp; Pak H Chan
Effects of neuroprotective dose of fructose-1,6-bisphosphate on hypoxia-induced expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices.
Brain research 1997;750(1-2):1-10.
1997: T Kondo; Frank R Sharp; J Honkaniemi; S Mikawa; C J Epstein; Pak H Chan
DNA fragmentation and Prolonged expression of c-fos, c-jun, and hsp70 in kainic acid-induced neuronal cell death in transgenic mice overexpressing human CuZn-superoxide dismutase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(3):241-56.
1997: Sydney Evans; M Bergeron; Donna M Ferriero; Frank R Sharp; H Hermeking; Richard N Kitsis; David L Geenen; S Bialik; EM Lord; Cameron J Koch
Imaging hypoxia in diseased tissues.
Advances in experimental medicine and biology 1997;428():595-603.
1997: S Sato; Glenn T Gobbel; Y Li; T Kondo; K Murakami; M Sato; K Hasegawa; Jean-Christophe Copin; J Honkaniemi; Frank R Sharp; Pak H Chan
Blood-brain barrier disruption, HSP70 expression and apoptosis due to 3-nitropropionic acid, a mitochondrial toxin.
Acta neurochirurgica. Supplement 1997;70():237-9.
1997: P G Matz; Philip R Weinstein; Frank R Sharp
Heme oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage.
Neurosurgery 1997;40(1):152-60; discussion 160-2.
1996: P Narasimhan; R Sklar; M Murrell; Raymond Swanson; Frank R Sharp
Methylmalonyl-CoA mutase induction by cerebral ischemia and neurotoxicity of the mitochondrial toxin methylmalonic acid.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(22):7336-46.
1996: J Honkaniemi; S M Massa; M Breckinridge; Frank R Sharp
Global ischemia induces apoptosis-associated genes in hippocampus.
Brain research. Molecular brain research 1996;42(1):79-88.
1996: B A States; J Honkaniemi; Philip R Weinstein; Frank R Sharp
DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(6):1165-75.
1996: P G Matz; S M Massa; Philip R Weinstein; C Turner; S Scott Panter; Frank R Sharp
Focal hyperexpression of hemeoxygenase-1 protein and messenger RNA in rat brain caused by cellular stress following subarachnoid injections of lysed blood.
Journal of neurosurgery 1996;85(5):892-900.
1996: T Kondo; K Murakami; J Honkaniemi; Frank R Sharp; Charles J Epstein; Pak H Chan
Expression of hsp70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia.
Brain research 1996;737(1-2):321-6.
1996: K Fukuda; Jeremy D Richmon; M Sato; Frank R Sharp; S Scott Panter; Linda J Noble
Induction of heme oxygenase-1 (HO-1) in glia after traumatic brain injury.
Brain research 1996;736(1-2):68-75.
1996: S Wang; Q Yang; C J Moller; Frank R Sharp; Kenneth G Haglid
Eliprodil prevents expression of the 70 kDa heat shock protein in MK801-injured neurones.
Pharmacology & toxicology 1996;79(3):166-8.
1996: J Honkaniemi; Frank R Sharp
Global ischemia induces immediate-early genes encoding zinc finger transcription factors.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):557-65.
1996: R Näkki; Frank R Sharp; S M Sagar; J Honkaniemi
Effects of phencyclidine on immediate early gene expression in the brain.
Journal of neuroscience research 1996;45(1):13-27.
1996: P G Matz; S Sundaresan; Frank R Sharp; Philip R Weinstein
Induction of HSP70 in rat brain following subarachnoid hemorrhage produced by endovascular perforation.
Journal of neurosurgery 1996;85(1):138-45.
1996: P Narasimhan; Raymond Swanson; S M Sagar; Frank R Sharp
Astrocyte survival and HSP70 heat shock protein induction following heat shock and acidosis.
Glia 1996;17(2):147-59.
1996: M C Longuemare; E C Keung; S Chun; Frank R Sharp; Pak H Chan; Raymond Swanson
MK-801 reduces uptake and stimulates efflux of excitatory amino acids via membrane depolarization.
The American journal of physiology 1996;270(5 Pt 1):C1398-404.
1996: K Fukuda; N Aihara; S M Sagar; Frank R Sharp; Lawrence H Pitts; J Honkaniemi; Linda J Noble
Purkinje cell vulnerability to mild traumatic brain injury.
Journal of neurotrauma 1996;13(5):255-66.
1996: T Nimura; Philip R Weinstein; S M Massa; S Scott Panter; Frank R Sharp
Heme oxygenase-1 (HO-1) protein induction in rat brain following focal ischemia.
Brain research. Molecular brain research 1996;37(1-2):201-8.
1996: P Matz; C Turner; Philip R Weinstein; S M Massa; S Scott Panter; Frank R Sharp
Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage.
Brain research 1996;713(1-2):211-22.
1996: P Matz; P Weinstein; B States; J Honkaniemi; Frank R Sharp
Subarachnoid injections of lysed blood induce the hsp70 stress gene and produce DNA fragmentation in focal areas of the rat brain.
Stroke; a journal of cerebral circulation 1996;27(3):504-12; discussion 513.
1996: R Nakki; J Nickolenko; J Chang; S M Sagar; Frank R Sharp
Haloperidol prevents ketamine- and phencyclidine-induced HSP70 protein expression but not microglial activation.
Experimental neurology 1996;137(2):234-41.
1996: R Näkki; Frank R Sharp; S M Sagar
FOS expression in the brainstem and cerebellum following phencyclidine and MK801.
Journal of neuroscience research 1996;43(2):203-12.
1996: J Honkaniemi; Stephen M Massa; Frank R Sharp
Apoptosis associated genes are induced in gerbil hippocampus following global ischemia.
Restorative neurology and neuroscience 1996;9(4):227-30.
1996: S M Massa; Raymond Swanson; Frank R Sharp
The stress gene response in brain.
Cerebrovascular and brain metabolism reviews 1996;8(2):95-158.
1995: Jeremy D Richmon; K Fukuda; Frank R Sharp; Linda J Noble
Induction of HSP-70 after hyperosmotic opening of the blood-brain barrier in the rat.
Neuroscience letters 1995;202(1-2):1-4.
1995: H Gaspary; Steven H Graham; S M Sagar; Frank R Sharp
HSP70 heat shock protein induction following global ischemia in the rat.
Brain research. Molecular brain research 1995;34(2):327-32.
1995: Shigeki Mikawa; Frank R Sharp; Hideyuki Kamii; Hiroyuki Kinouchi; Charles J Epstein; P K Chan
Expression of c-fos and hsp70 mRNA after traumatic brain injury in transgenic mice overexpressing CuZn-superoxide dismutase.
Brain research. Molecular brain research 1995;33(2):288-94.
1995: K Fukuda; S Scott Panter; Frank R Sharp; Linda J Noble
Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat.
Neuroscience letters 1995;199(2):127-30.
1995: Frank R Sharp
Stress proteins are sensitive indicators of injury in the brain produced by ischemia and toxins.
The Journal of toxicological sciences 1995;20(4):450-3.
1995: L L Brown; Frank R Sharp
Metabolic mapping of rat striatum: somatotopic organization of sensorimotor activity.
Brain research 1995;686(2):207-22.
1995: K Hisanaga; S Kure; Dale E Bredesen; Y Ikeda; S Kohsaka; Frank R Sharp
Apoptotic cell death of a temperature-sensitive central neuronal cell line.
Brain research 1995;684(1):79-86.
1995: Stephen M Massa; Frank M Longo; J Zuo; S Wang; J Chen; Frank R Sharp
Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain.
Journal of neuroscience research 1995;40(6):807-19.
1995: R Näkki; Jari Koistinaho; Frank R Sharp; S M Sagar
Cerebellar toxicity of phencyclidine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 2):2097-108.
1995: Frank R Sharp; Jialing Liu; J Nickolenko; B Bontempi
NMDA and D1 receptors mediate induction of c-fos and junB genes in striatum following morphine administration: implications for studies of memory.
Behavioural brain research 1995;66(1-2):225-30.
1995: S M Sagar; K J Price; N W Kasting; Frank R Sharp
Anatomic patterns of Fos immunostaining in rat brain following systemic endotoxin administration.
Brain research bulletin 1995;36(4):381-92.
1995: J Honkaniemi; S M Sagar; I Pyykönen; K J Hicks; Frank R Sharp
Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors.
Brain research. Molecular brain research 1995;28(1):157-63.
1994: Frank R Sharp; T A Rando; Steven A Greenberg; L Brown; S M Sagar
Pseudochoreoathetosis. Movements associated with loss of proprioception.
Archives of neurology 1994;51(11):1103-9.
1994: Hideyuki Kamii; Hiroyuki Kinouchi; Frank R Sharp; Charles J Epstein; S M Sagar; Pak H Chan
Expression of c-fos mRNA after a mild focal cerebral ischemia in SOD-1 transgenic mice.
Brain research 1994;662(1-2):240-4.
1994: Frank R Sharp
The sense of antisense fos oligonucleotides.
Annals of neurology 1994;36(4):555-6.
1994: Frank R Sharp; M Butman; Jari Koistinaho; K Aardalen; R Nakki; S M Massa; Raymond Swanson; S M Sagar
Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via multiple receptors and voltage gated calcium channels.
Neuroscience 1994;62(4):1079-92.
1994: Hiroyuki Kinouchi; Frank R Sharp; Pak H Chan; Shigeki Mikawa; Hideyuki Kamii; S Arai; Takashi Yoshimoto
MK-801 inhibits the induction of immediate early genes in cerebral cortex, thalamus, and hippocampus, but not in substantia nigra following middle cerebral artery occlusion.
Neuroscience letters 1994;179(1-2):111-4.
1994: Hiroyuki Kinouchi; Frank R Sharp; Pak H Chan; J Koistinaho; S M Sagar; Takashi Yoshimoto
Induction of c-fos, junB, c-jun, and hsp70 mRNA in cortex, thalamus, basal ganglia, and hippocampus following middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(5):808-17.
1994: Jialing Liu; J Nickolenko; Frank R Sharp
Morphine induces c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-D-aspartate receptors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8537-41.
1994: Raymond Swanson; Frank R Sharp
Infarct measurement methodology.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(4):697-8.
1994: Hideyuki Kamii; Hiroyuki Kinouchi; Frank R Sharp; Jari Koistinaho; Charles J Epstein; Pak H Chan
Prolonged expression of hsp70 mRNA following transient focal cerebral ischemia in transgenic mice overexpressing CuZn-superoxide dismutase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(3):478-86.
1994: H Kinouchi; Frank R Sharp; P H Chan; J Koistinaho; S M Sagar; Takashi Yoshimoto
Induction of NGFI-A mRNA following middle cerebral artery occlusion in rats: in situ hybridization study.
Neuroscience letters 1994;171(1-2):163-6.
1994: Steven H Graham; Dieter Meyerhoff; L Bayne; Frank R Sharp; Michael Weiner
Magnetic resonance spectroscopy of N-acetylaspartate in hypoxic-ischemic encephalopathy.
Annals of neurology 1994;35(4):490-4.
1994: S P Ciricillo; M P Hill; M F Gonzalez; S Smalley; M T Morton; Frank R Sharp
Whisker stimulation metabolically activates thalamus following cortical transplantation but not following cortical ablation.
Neuroscience 1994;59(4):975-92.
1994: P Berger; K Farrel; Frank R Sharp; P Skolnick
Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex.
Neuroscience letters 1994;168(1-2):147-50.
1994: Frank R Sharp; S M Sagar
Alterations in gene expression as an index of neuronal injury: heat shock and the immediate early gene response.
Neurotoxicology 1994;15(1):51-9.
1994: Raymond Swanson; Frank R Sharp
BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage.
Stroke; a journal of cerebral circulation 1994;25(1):225-6.
1994: Frank R Sharp; M Butman; K Aardalen; J Nickolenko; R Nakki; S M Massa; Raymond Swanson; S M Sagar
Neuronal injury produced by NMDA antagonists can be detected using heat shock proteins and can be blocked with antipsychotics.
Psychopharmacology bulletin 1994;30(4):555-60.
1993: S Wang; Frank M Longo; J Chen; M Butman; Steven H Graham; K G Haglid; Frank R Sharp
Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia.
Neurochemistry international 1993;23(6):575-82.
1993: Frank R Sharp; Hiroyuki Kinouchi; Jari Koistinaho; Pak H Chan; S M Sagar
HSP70 heat shock gene regulation during ischemia.
Stroke; a journal of cerebral circulation 1993;24(12 Suppl):I72-5.
1993: Frank M Longo; S Wang; P Narasimhan; J S Zhang; J Chen; Stephen M Massa; Frank R Sharp
cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain.
Journal of neuroscience research 1993;36(3):325-35.
1993: Frank R Sharp
Transplants for stroke patients?
Annals of neurology 1993;34(3):322-3.
1993: Hiroyuki Kinouchi; Frank R Sharp; Jari Koistinaho; K Hicks; Hideyuki Kamii; Pak H Chan
Induction of heat shock hsp70 mRNA and HSP70 kDa protein in neurons in the 'penumbra' following focal cerebral ischemia in the rat.
Brain research 1993;619(1-2):334-8.
1993: K Hisanaga; S M Sagar; Jari Koistinaho; K J Hicks; Frank R Sharp
VIP-induced stellation and immediate early gene expression in astrocytes: effects of dexamethasone.
Neuroscience letters 1993;156(1-2):57-60.
1993: Frank R Sharp; M Butman; S Wang; Jari Koistinaho; Steven H Graham; S M Sagar; P Berger; Frank M Longo
Heat shock proteins used to show that haloperidol prevents neuronal injury produced by ketamine, MK801, and phencyclidine.
Annals of the New York Academy of Sciences 1993;679():288-90.
1993: S M Sagar; Frank R Sharp
Early response genes as markers of neuronal activity and growth factor action.
Advances in neurology 1993;59():273-84.
1993: Frank R Sharp
Regulatory genes in regeneration and plasticity.
Advances in neurology 1993;59():257-61.
1993: Hiroyuki Kinouchi; Frank R Sharp; M P Hill; Jari Koistinaho; S M Sagar; Pak H Chan
Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):105-15.
1993: Frank R Sharp; K Hisanaga; S M Sagar
NMDA receptor blockade prevents translation, but not transcription, of the c-fos gene following stimulation with multiple extracellular signals in cultured cortical neurons: implications for plasticity and molecular memory.
NIDA research monograph 1993;125():172-80.
1993: Frank R Sharp; S M Sagar; Raymond Swanson
Metabolic mapping with cellular resolution: c-fos vs. 2-deoxyglucose.
Critical reviews in neurobiology 1993;7(3-4):205-28.
1993: Steven H Graham; J Chen; Frank R Sharp; Roger P. Simon
Limiting ischemic injury by inhibition of excitatory amino acid release.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):88-97.
1992: Frank R Sharp; M Butman; S Wang; Jari Koistinaho; Steven H Graham; S M Sagar; Linda J Noble; P Berger; Frank M Longo
Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine.
Journal of neuroscience research 1992;33(4):605-16.
1992: Raymond Swanson; M M Morton; S M Sagar; Frank R Sharp
Sensory stimulation induces local cerebral glycogenolysis: demonstration by autoradiography.
Neuroscience 1992;51(2):451-61.
1992: K Hisanaga; S M Sagar; Frank R Sharp
Ascorbate neurotoxicity in cortical cell culture.
Annals of neurology 1992;31(5):562-5.
1992: K Hisanaga; S M Sagar; Frank R Sharp
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Journal of neurochemistry 1992;58(5):1836-44.
1992: K Hisanaga; S M Sagar; Frank R Sharp
C-fos induction occurs in cultured cortical neurons and astrocytes via multiple signaling pathways.
Progress in brain research 1992;94():189-95.
1992: Raymond Swanson; Frank R Sharp
Zinc toxicity and induction of the 72 kD heat shock protein in primary astrocyte culture.
Glia 1992;6(3):198-205.
1991: Frank R Sharp; P Jasper; J Hall; Linda J Noble; S M Sagar
MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex.
Annals of neurology 1991;30(6):801-9.
1991: Raymond Swanson; Frank R Sharp
Glucose and infarct size.
Neurology 1991;41(12):2013.
1991: Samuel F Ciricillo; M P Jasper; M F Gonzalez; Frank R Sharp
Long experimental durations are required for double label [14C]- and [3H]2-deoxyglucose autoradiographic methods.
Brain research 1991;564(1):171-5.
1991: Frank R Sharp; S M Sagar; K Hicks; Daniel H Lowenstein; K Hisanaga
c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(8):2321-31.
1991: S M Sagar; Robert H Edwards; Frank R Sharp
Epidermal growth factor and transforming growth factor alpha induce c-fos gene expression in retinal Muller cells in vivo.
Journal of neuroscience research 1991;29(4):549-59.
1991: Frank R Sharp; Daniel H Lowenstein; Roger P. Simon; K Hisanaga
Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1991;11(4):621-7.
1991: M F Gonzalez; Daniel H Lowenstein; S Fernyak; K Hisanaga; Roger P. Simon; Frank R Sharp
Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia.
Brain research bulletin 1991;26(2):241-50.
1991: Neil Aronin; Kathryn O Chase; S M Sagar; Frank R Sharp; Marian DiFiglia
N-methyl-D-aspartate receptor activation in the neostriatum increases c-fos and fos-related antigens selectively in medium-sized neurons.
Neuroscience 1991;44(2):409-20.
1991: R Sandor; M F Gonzalez; M Moseley; Frank R Sharp
Motor deficits are produced by removing some cortical transplants grafted into injured sensorimotor cortex of neonatal rats.
Journal of neural transplantation & plasticity 1991;2(3-4):221-33.
1990: Daniel H Lowenstein; Roger P. Simon; Frank R Sharp
The pattern of 72-kDa heat shock protein-like immunoreactivity in the rat brain following flurothyl-induced status epilepticus.
Brain research 1990;531(1-2):173-82.
1990: J W Sharp; S M Sagar; K Hisanaga; P Jasper; Frank R Sharp
The NMDA receptor mediates cortical induction of fos and fos-related antigens following cortical injury.
Experimental neurology 1990;109(3):323-32.
1990: Neil Aronin; S M Sagar; Frank R Sharp; William J Schwartz
Light regulates expression of a Fos-related protein in rat suprachiasmatic nuclei.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5959-62.
1990: K Hisanaga; Frank R Sharp
Marked neurotrophic effects of diffusible substances released from non-target cerebellar cells on thalamic neurons in culture.
Brain research. Developmental brain research 1990;54(2):151-60.
1990: Thomas Kilduff; JD Miller; C M Radeke; Frank R Sharp; H Craig Heller
14C-2-deoxyglucose uptake in the ground squirrel brain during entrance to and arousal from hibernation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(7):2463-75.
1990: K Hisanaga; S M Sagar; K J Hicks; Raymond Swanson; Frank R Sharp
c-fos proto-oncogene expression in astrocytes associated with differentiation or proliferation but not depolarization.
Brain research. Molecular brain research 1990;8(1):69-75.
1990: Donna M Ferriero; H Q Soberano; Roger P. Simon; Frank R Sharp
Hypoxia-ischemia induces heat shock protein-like (HSP72) immunoreactivity in neonatal rat brain.
Brain research. Developmental brain research 1990;53(1):145-50.
1990: L Jacobson; Frank R Sharp; Mary F Dallman
Induction of fos-like immunoreactivity in hypothalamic corticotropin-releasing factor neurons after adrenalectomy in the rat.
Endocrinology 1990;126(3):1709-19.
1990: Raymond Swanson; M T Morton; G Tsao-Wu; R A Savalos; C Davidson; Frank R Sharp
A semiautomated method for measuring brain infarct volume.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(2):290-3.
1990: Raymond Swanson; K Shiraishi; M T Morton; Frank R Sharp
Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion.
Stroke; a journal of cerebral circulation 1990;21(2):322-7.
1990: Dale E Bredesen; K Hisanaga; Frank R Sharp
Neural transplantation using temperature-sensitive immortalized neural cells: a preliminary report.
Annals of neurology 1990;27(2):205-7.
1990: Raymond Swanson; A C Yu; P H Chan; Frank R Sharp
Glutamate increases glycogen content and reduces glucose utilization in primary astrocyte culture.
Journal of neurochemistry 1990;54(2):490-6.
1990: K Hisanaga; Frank R Sharp
Diffusible neurotrophic factors for thalamic neurons are released from target neocortex and non-target cerebellum.
Progress in brain research 1990;82():67-71.
1990: S M Sagar; Frank R Sharp
Light induces a Fos-like nuclear antigen in retinal neurons.
Brain research. Molecular brain research 1990;7(1):17-21.
1990: M F Gonzalez; Frank R Sharp
Fetal cortical transplants surviving in injured sensorimotor cortex of rats: cellular composition and function.
Progress in brain research 1990;82():309-12.
1989: K Shiraishi; Frank R Sharp; Roger P. Simon
Sequential metabolic changes in rat brain following middle cerebral artery occlusion: a 2-deoxyglucose study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(6):765-73.
1989: Frank R Sharp; J Griffith; M F Gonzalez; S M Sagar
Trigeminal nerve section induces Fos-like immunoreactivity (FLI) in brainstem and decreases FLI in sensory cortex.
Brain research. Molecular brain research 1989;6(2-3):217-20.
1989: Thomas Kilduff; C M Radeke; T L Randall; Frank R Sharp; H Craig Heller
Suprachiasmatic nucleus: phase-dependent activation during the hibernation cycle.
The American journal of physiology 1989;257(3 Pt 2):R605-12.
1989: M F Gonzalez; K Shiraishi; K Hisanaga; S M Sagar; M Mandabach; Frank R Sharp
Heat shock proteins as markers of neural injury.
Brain research. Molecular brain research 1989;6(1):93-100.
1989: Frank R Sharp; M F Gonzalez; J W Sharp; S M Sagar
c-fos expression and (14C) 2-deoxyglucose uptake in the caudal cerebellum of the rat during motor/sensory cortex stimulation.
The Journal of comparative neurology 1989;284(4):621-36.
1989: Frank R Sharp; M F Gonzalez; K Hisanaga; William C. Mobley; S M Sagar
Induction of the c-fos gene product in rat forebrain following cortical lesions and NGF injections.
Neuroscience letters 1989;100(1-3):117-22.
1989: Raymond Swanson; A C Yu; Frank R Sharp; P H Chan
Regulation of glycogen content in primary astrocyte culture: effects of glucose analogues, phenobarbital, and methionine sulfoximine.
Journal of neurochemistry 1989;52(5):1359-65.
1989: Raymond Swanson; S M Sagar; Frank R Sharp
Regional brain glycogen stores and metabolism during complete global ischaemia.
Neurological research 1989;11(1):24-8.
1988: T J Mampalam; M F Gonzalez; P Weinstein; Frank R Sharp
Neuronal changes in fetal cortex transplanted to ischemic adult rat cortex.
Journal of neurosurgery 1988;69(6):904-12.
1988: S H Graham; Frank R Sharp; W Dillon
Intraoral sensation in patients with brainstem lesions: role of the rostral spinal trigeminal nuclei in pons.
Neurology 1988;38(10):1529-33.
1988: Thomas Kilduff; Frank R Sharp; H Craig Heller
Progressive activation of paratrigeminal nucleus during entrance to hibernation.
The American journal of physiology 1988;255(1 Pt 2):R178-81.
1988: S M Sagar; Frank R Sharp; T Curran
Expression of c-fos protein in brain: metabolic mapping at the cellular level.
Science (New York, N.Y.) 1988;240(4857):1328-31.
1988: Frank R Sharp; M F Gonzalez; C W Morgan; M T Morton; J W Sharp
Common fur and mystacial vibrissae parallel sensory pathways: 14 C 2-deoxyglucose and WGA-HRP studies in the rat.
The Journal of comparative neurology 1988;270(3):446-69.
1988: J W Sharp; M F Gonzalez; M T Morton; Roger P. Simon; Frank R Sharp
Decreases of cortical and thalamic glucose metabolism produced by parietal cortex stimulation in the rat.
Brain research 1988;438(1-2):357-62.
1988: M F Gonzalez; Frank R Sharp; J E Loken
Fetal frontal cortex transplanted to injured motor/sensory cortex of adult rats: reciprocal connections with host thalamus demonstrated with WGA-HRP.
Experimental neurology 1988;99(1):154-65.
1987: M F Gonzalez; Frank R Sharp
Fetal frontal cortex transplanted to injured motor/sensory cortex of adult rats. I. NADPH-diaphorase neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(10):2991-3001.
1987: Frank R Sharp; M F Gonzalez; S M Sagar
Fetal frontal cortex transplanted to injured motor/sensory cortex of adult rats. II. VIP-, somatostatin-, and NPY-immunoreactive neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(10):3002-15.
1987: M J Selby; R Edwards; Frank R Sharp; W J Rutter
Mouse nerve growth factor gene: structure and expression.
Molecular and cellular biology 1987;7(9):3057-64.
1987: S M Sagar; Frank R Sharp; Raymond Swanson
The regional distribution of glycogen in rat brain fixed by microwave irradiation.
Brain research 1987;417(1):172-4.
1987: M F Gonzalez; Frank R Sharp; S M Sagar
Axotomy increases NADPH-diaphorase staining in rat vagal motor neurons.
Brain research bulletin 1987;18(3):417-27.
1986: Frank R Sharp; M F Gonzalez
Adult rat motor cortex connections to thalamus following neonatal and juvenile frontal cortical lesions: WGA-HRP and amino acid studies.
Brain research 1986;395(2):169-87.
1986: Frank R Sharp; M F Gonzalez
Fetal cortical transplants ameliorate thalamic atrophy ipsilateral to neonatal frontal cortex lesions.
Neuroscience letters 1986;71(2):247-51.
1986: M F Gonzalez; A Poncelet; J E Loken; Frank R Sharp
Quantitative measurement of interresponse times to assess forelimb motor function in rats.
Behavioural brain research 1986;22(1):75-84.
1986: W H Luyten; Frank R Sharp; A F Ryan
Regional differences of brain glucose metabolic compensation after unilateral labyrinthectomy in rats: a [14C]2-deoxyglucose study.
Brain research 1986;373(1-2):68-80.
1986: Frank R Sharp; M F Gonzalez; D M Ferriero; S M Sagar
Injured adult neocortical neurons sprout fibers into surviving fetal frontal cortex transplants: evidence using NADPH-diaphorase staining.
Neuroscience letters 1986;65(2):204-8.
1986: M F Gonzalez; Frank R Sharp; J A Deutsch
Gastric distention increases [14C]2-deoxyglucose uptake in the rat nucleus tractus solitarius.
Brain research 1986;369(1-2):395-9.
1985: D L McEachron; D F Kripke; Frank R Sharp; Alfred J Lewy; D E McClellan
Lithium effects on selected circadian rhythms in rats.
Brain research bulletin 1985;15(3):347-50.
1985: M F Gonzalez; Frank R Sharp
Reticular nucleus of rat thalamus is metabolically activated during trained forelimb movements.
Brain research 1985;332(2):380-5.
1985: Frank R Sharp; M F Gonzalez
Multiple vibrissae sensory regions in rat cerebellum: a (14C) 2-deoxyglucose study.
The Journal of comparative neurology 1985;234(4):489-500.
1985: M F Gonzalez; Frank R Sharp
Vibrissae tactile stimulation: (14C) 2-deoxyglucose uptake in rat brainstem, thalamus, and cortex.
The Journal of comparative neurology 1985;231(4):457-72.
1984: Frank R Sharp; M F Gonzalez
Fetal frontal cortex transplant (14C) 2-deoxyglucose uptake and histology: survival in cavities of host rat brain motor cortex.
Neurology 1984;34(10):1305-11.
1984: P C Goodwin; A F Ryan; Frank R Sharp; N K Woolf; T M Davidson
Cochlear deoxyglucose uptake: relationship to stimulus intensity.
Hearing research 1984;15(3):215-24.
1984: Frank R Sharp; Allen F Ryan
Regional (14C) 2-deoxyglucose uptake during forelimb movements evoked by rat motor cortex stimulation: pons, cerebellum, medulla, spinal cord, muscle.
The Journal of comparative neurology 1984;224(2):286-306.
1984: Frank R Sharp
Regional (14C) 2-deoxyglucose uptake during forelimb movements evoked by rat motor cortex stimulation: cortex, diencephalon, midbrain.
The Journal of comparative neurology 1984;224(2):259-85.
1983: N K Woolf; Frank R Sharp; T M Davidson; A F Ryan
Cochlear and middle ear effects on metabolism in the central auditory pathway during silence: a 2-deoxyglucose study.
Brain research 1983;274(1):119-27.
1983: Thomas Kilduff; C P George; Frank R Sharp; H Craig Heller
Metabolic activation of the brachium conjunctivum during induced hypothermia.
Brain research 1983;269(1):168-71.
1983: Frank R Sharp; Thomas Kilduff; S Bzorgchami; H Craig Heller; A F Ryan
The relationship of local cerebral glucose utilization to optical density ratios.
Brain research 1983;263(1):97-103.
1983: Frank R Sharp; S Bzorgchami; Thomas Kilduff
Focal increases of white matter glucose utilization produced by electrical stimulation of rat motor cortex.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1983;3(1):67-70.
1983: Thomas Kilduff; Frank R Sharp; H Craig Heller
Relative 2-deoxyglucose uptake of the paratrigeminal nucleus increases during hibernation.
Brain research 1983;262(1):117-23.
1983: G K Bigley; Frank R Sharp
Reversible alexia without agraphia due to migraine.
Archives of neurology 1983;40(2):114-5.
1982: C P George; Thomas Kilduff; Frank R Sharp; H Craig Heller
Autoradiographic patterns of hippocampal metabolism during induced hypothermia.
Neuroscience letters 1982;34(3):233-9.
1982: A F Ryan; Frank R Sharp
Localization of [3H]2-deoxyglucose at the cellular level using freeze-dried tissue and dry-looped emulsion.
Brain research 1982;252(1):177-80.
1982: Frank R Sharp; K L Evans
Bilateral [14C]2-deoxyglucose uptake by motor pathways after unilateral neonatal cortex lesions in the rat.
Brain research 1982;282(1):1-11.
1982: Frank R Sharp; K Evans; E Bolger
Local cerebral glucose utilization in the symptomatic thiamine-deficient rat: increases in fornix and pyramidal tract.
Neurology 1982;32(8):808-14.
1982: Frank R Sharp; K Evans
Regional (14C) 2-deoxyglucose uptake during vibrissae movements evoked by rat motor cortex stimulation.
The Journal of comparative neurology 1982;208(3):255-87.
1982: A F Ryan; N K Woolf; Frank R Sharp
Tonotopic organization in the central auditory pathway of the Mongolian gerbil: a 2-deoxyglucose study.
The Journal of comparative neurology 1982;207(4):369-80.
1982: A F Ryan; P Goodwin; N K Woolf; Frank R Sharp
Auditory stimulation alters the pattern of 2-deoxyglucose uptake in the inner ear.
Brain research 1982;234(2):213-25.
1982: Thomas Kilduff; Frank R Sharp; H Craig Heller
[14C]2-deoxyglucose uptake in ground squirrel brain during hibernation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(2):143-57.
1982: A F Ryan; N K Woolf; Frank R Sharp
Functional ontogeny in the central auditory pathway of the Mongolian gerbil. A 2-deoxyglucose study.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1982;47(3):428-36.
1982: Frank R Sharp; E Bolger; K Evans
Thiamine deficiency limits glucose utilization and glial proliferation in brain lesions of symptomatic rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1982;2(2):203-7.
1981: Frank R Sharp; A F Ryan; P Goodwin; N K Woolf
Increasing intensities of wide band noise increase [14C]2-deoxyglucose uptake in gerbil central auditory structures.
Brain research 1981;230(1-2):87-96.
1981: J Schim; P Lyden; Frank R Sharp
Increased subcortical and laminar cortical 2-deoxy[14C]glucose uptake during cerebellar stimulation.
Experimental neurology 1981;74(2):499-518.
1981: J E Sander; Frank R Sharp
Lumbosacral plexus neuritis.
Neurology 1981;31(4):470-3.
1978: K S Hansen; Frank R Sharp
Gasoline sniffing, lead poisoning, and myoclonus.
JAMA : the journal of the American Medical Association 1978;240(13):1375-6.
1978: W J Schwartz; Frank R Sharp
Autoradiographic maps of regional brain glucose consumption in resting, awake rats using (14C) 2-deoxyglucose.
The Journal of comparative neurology 1978;177(2):335-59.
1977: Frank R Sharp; W J Schwartz
Proposed effects of brain noradrenaline on neuronal activity and cerebral blood flow during REM sleep.
Experientia 1977;33(12):1618-20.
1977: Frank R Sharp; J S Kauer; G M Shepherd
Laminar analysis of 2-deoxyglucose uptake in olfactory bulb and olfactory cortex of rabbit and rat.
Journal of neurophysiology 1977;40(4):800-13.
1977: R H Davis; K L Sisco; Frank R Sharp
Protein synthetic activity in nervous tissue from different anatomical regions of lobster.
Comparative biochemistry and physiology. B, Comparative biochemistry 1977;57(1):65-71.
1976: Frank R Sharp
Vestibular stimulation.
Neurosciences Research Program bulletin 1976;14(4):490-2.
1976: Frank R Sharp; L Sokoloff
Relation of central nervous system glucose metabolism to neuronal structure. Sciatic nerve stimulation.
Neurosciences Research Program bulletin 1976;14(4):476-8.
1976: Frank R Sharp
Improved resolution of the [1-14C]-2-deoxy-D-glucose technique and tissue localization.
Neurosciences Research Program bulletin 1976;14(4):468-73.
1976: Frank R Sharp
General motor activity.
Neurosciences Research Program bulletin 1976;14(4):492-6.
1976: Frank R Sharp
Rotation induced increases of glucose uptake in rat vestibular nuclei and vestibulocerebellum.
Brain research 1976;110(1):141-51.
1976: Frank R Sharp
Relative cerebral glucose uptake of neuronal perikarya and neuropil determined with 2-deoxyglucose in resting and swimming rat.
Brain research 1976;110(1):127-39.
1976: Frank R Sharp
Activity-related increases of glucose utilization associated with reduced incorporation of glucose into its derivatives.
Brain research 1976;107(3):663-6.
1976: W J Schwartz; Frank R Sharp; R H Gunn; E V Evarts
Lesions of ascending dopaminergic pathways decrease forebrain glucose uptake.
Nature 1976;261(5556):155-7.
1976: W J Schwartz; R H Gunn; Frank R Sharp; E V Evarts
Unilateral electrolytic lesions of the substantia nigra cause contralateral circling in rats.
Brain research 1976;105(2):358-61.
1975: Frank R Sharp; J S Kauer; G M Shepherd
Local sites of activity-related glucose metabolism in rat olfactory bulb during olfactory stimulation.
Brain research 1975;98(3):596-600.
1973: H T Hammel; H Craig Heller; Frank R Sharp
Probing the rostral brainstem of anesthetized, unanesthetized, and exercising dogs and of hibernating and euthermic ground squirrels.
Federation proceedings 1973;32(5):1588-97.
1972: Frank R Sharp; H T Hammel
Effects of chloralose-urethan anesthesia on temperature regulation in dogs.
Journal of applied physiology 1972;33(2):229-33.
1972: Frank R Sharp; H T Hammel
Effects of fever on salivation response in the resting and exercising dog.
The American journal of physiology 1972;223(1):77-82.