Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Carl Blobel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Amino Acid Sequence

Concepts & Ideas

Anatomy

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Franzke Claus-Werner; Bruckner-Tuderman Leena; Blobel Carl P
Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.
Maretzky Thorsten; Le Gall Sylvain M; Worpenberg-Pietruk Susanne; Eder Jörg; Overall Christopher M; Huang Xin-Yun; Poghosyan Zaruhi; Edwards Dylan R; Blobel Carl P
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Guaiquil Victor; Swendeman Steven; Yoshida Tsunehiko; Chavala Sai; Campochiaro Peter A; Blobel Carl P
ADAM9 is involved in pathological retinal neovascularization.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Carl Blobel (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Franzke Claus-Werner; Bruckner-Tuderman Leena; Blobel Carl P
Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.
The Journal of biological chemistry 2009;284(35):23386-96.
2009: Maretzky Thorsten; Le Gall Sylvain M; Worpenberg-Pietruk Susanne; Eder Jörg; Overall Christopher M; Huang Xin-Yun; Poghosyan Zaruhi; Edwards Dylan R; Blobel Carl P
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Cancer research 2009;69(11):4573-6.
2009: Guaiquil Victor; Swendeman Steven; Yoshida Tsunehiko; Chavala Sai; Campochiaro Peter A; Blobel Carl P
ADAM9 is involved in pathological retinal neovascularization.
Molecular and cellular biology 2009;29(10):2694-703.
2009: Maretzky Thorsten; Yang Guangli; Ouerfelli Ouathek; Overall Christopher M; Worpenberg Susanne; Hassiepen Ulrich; Eder Joerg; Blobel Carl P
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
The Biochemical journal 2009;420(1):105-13.
2009: Le Gall Sylvain M; Bobé Pierre; Reiss Karina; Horiuchi Keisuke; Niu Xiao-Da; Lundell Daniel; Gibb David R; Conrad Daniel; Saftig Paul; Blobel Carl P
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.
Molecular biology of the cell 2009;20(6):1785-94.
2009: Horiuchi Keisuke; Kimura Tokuhiro; Miyamoto Takeshi; Miyamoto Kana; Akiyama Haruhiko; Takaishi Hironari; Morioka Hideo; Nakamura Takashi; Okada Yasunori; Blobel Carl P; Toyama Yoshiaki
Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2093-101.
2009: Blobel Carl P; Carpenter Graham; Freeman Matthew
The role of protease activity in ErbB biology.
Experimental cell research 2009;315(4):671-82.
2008: Swendeman Steven; Mendelson Karen; Weskamp Gisela; Horiuchi Keisuke; Deutsch Urban; Scherle Peggy; Hooper Andrea; Rafii Shahin; Blobel Carl P
VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.
Circulation research 2008;103(9):916-8.
2008: Harsha Asheesh; Stojadinovic Olivera; Brem Harold; Sehara-Fujisawa Atsuko; Wewer Ulla; Loomis Cynthia A; Blobel Carl P; Tomic-Canic Marjana
ADAM12: a potential target for the treatment of chronic wounds.
Journal of molecular medicine (Berlin, Germany) 2008;86(8):961-9.
2007: Horiuchi Keisuke; Miyamoto Takeshi; Takaishi Hironari; Hakozaki Akihiro; Kosaki Naoto; Miyauchi Yoshiteru; Furukawa Mitsuru; Takito Jiro; Kaneko Hironori; Matsuzaki Kenichiro; Morioka Hideo; Blobel Carl P; Toyama Yoshiaki
Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6715-24.
2007: Horiuchi Keisuke; Kimura Tokuhiro; Miyamoto Takeshi; Takaishi Hironari; Okada Yasunori; Toyama Yoshiaki; Blobel Carl P
Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):2686-9.
2007: Zhu Wei; Boachie-Adjei Oheneba; Rawlins Bernard A; Frenkel Baruch; Boskey Adele L; Ivashkiv Lionel B; Blobel Carl P
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells.
The Journal of biological chemistry 2007;282(26):18676-85.
2007: Kawaguchi Nobuko; Horiuchi Keisuke; Becherer J David; Toyama Yoshiaki; Besmer Peter; Blobel Carl P
Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.
Journal of cell science 2007;120(Pt 6):943-52.
2007: Sahin Umut; Blobel Carl P
Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17.
FEBS letters 2007;581(1):41-4.
2007: Dyczynska Emilia; Sun Danqiong; Yi Haiqing; Sehara-Fujisawa Atsuko; Blobel Carl P; Zolkiewska Anna
Proteolytic processing of delta-like 1 by ADAM proteases.
The Journal of biological chemistry 2007;282(1):436-44.
2007: Horiuchi Keisuke; Le Gall Sylvain; Schulte Marc; Yamaguchi Takafumi; Reiss Karina; Murphy Gillian; Toyama Yoshiaki; Hartmann Dieter; Saftig Paul; Blobel Carl P
Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
Molecular biology of the cell 2007;18(1):176-88.
2006: Weskamp Gisela; Ford Jill W; Sturgill Jamie; Martin Steve; Docherty Andrew J P; Swendeman Steven; Broadway Neil; Hartmann Dieter; Saftig Paul; Umland Shelby; Sehara-Fujisawa Atsuko; Black Roy A; Ludwig Andreas; Becherer J David; Conrad Daniel H; Blobel Carl P
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.
Nature immunology 2006;7(12):1293-8.
2006: Peduto L; Reuter V E; Sehara-Fujisawa A; Shaffer D R; Scher H I; Blobel C P
ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression.
Oncogene 2006;25(39):5462-6.
2006: Sahin Umut; Weskamp Gisela; Zheng Yufang; Chesneau Valerie; Horiuchi Keisuke; Blobel Carl P
A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptor.
Methods in molecular biology (Clifton, N.J.) 2006;327():99-113.
2005: Peduto Lucie; Reuter Victor E; Shaffer David R; Scher Howard I; Blobel Carl P
Critical function for ADAM9 in mouse prostate cancer.
Cancer research 2005;65(20):9312-9.
2005: Horiuchi Keisuke; Zhou Hong-Ming; Kelly Kristine; Manova Katia; Blobel Carl P
Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2.
Developmental biology 2005;283(2):459-71.
2005: Böhm Beate B; Aigner Thomas; Roy Barbara; Brodie Thomas A; Blobel Carl P; Burkhardt Harald
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.
Arthritis and rheumatism 2005;52(4):1100-9.
2005: Blobel Carl P
ADAMs: key components in EGFR signalling and development.
Nature reviews. Molecular cell biology 2005;6(1):32-43.
2005: Kelly Kristine; Hutchinson Gillian; Nebenius-Oosthuizen Daniela; Smith Andrew J H; Bartsch Jörg W; Horiuchi Keisuke; Rittger Andrea; Manova Katia; Docherty Andy J P; Blobel Carl P
Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;232(1):221-31.
2004: Zheng Yufang; Saftig Paul; Hartmann Dieter; Blobel Carl
Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17).
The Journal of biological chemistry 2004;279(41):42898-906.
2004: Sahin Umut; Weskamp Gisela; Kelly Kristine; Zhou Hong-Ming; Higashiyama Shigeki; Peschon Jacques; Hartmann Dieter; Saftig Paul; Blobel Carl P
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
The Journal of cell biology 2004;164(5):769-79.
2004: Weskamp Gisela; Schlöndorff Johannes; Lum Lawrence; Becherer J David; Kim Tae-Wan; Saftig Paul; Hartmann Dieter; Murphy Gillian; Blobel Carl P
Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).
The Journal of biological chemistry 2004;279(6):4241-9.
2004: Zhou Hong-Ming; Weskamp Gisela; Chesneau Valérie; Sahin Umut; Vortkamp Andrea; Horiuchi Keisuke; Chiusaroli Riccardo; Hahn Rebecca; Wilkes David; Fisher Peter; Baron Roland; Manova Katia; Basson Craig T; Hempstead Barbara; Blobel Carl P
Essential role for ADAM19 in cardiovascular morphogenesis.
Molecular and cellular biology 2004;24(1):96-104.
2003: Horiuchi Keisuke; Weskamp Gisela; Lum Lawrence; Hammes Hans-Peter; Cai Hui; Brodie Thomas A; Ludwig Thomas; Chiusaroli Riccardo; Baron Roland; Preissner Klaus T; Manova Katia; Blobel Carl P
Potential role for ADAM15 in pathological neovascularization in mice.
Molecular and cellular biology 2003;23(16):5614-24.
2003: Borroto Aldo; Ruiz-Paz Soraya; de la Torre Teresa Villanueva; Borrell-Pages Maria; Merlos-Suarez Anna; Pandiella Atanasio; Blobel Carl P; Baselga Josep; Arribas Joaquin
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.
The Journal of biological chemistry 2003;278(28):25933-9.
2003: Chesneau Valérie; Becherer J David; Zheng Yufang; Erdjument-Bromage Hediye; Tempst Paul; Blobel Carl P
Catalytic properties of ADAM19.
The Journal of biological chemistry 2003;278(25):22331-40.
2003: Becherer J David; Blobel Carl P
Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs).
Current topics in developmental biology 2003;54():101-23.
2002: Amour Augustin; Knight C Graham; English William R; Webster Ailsa; Slocombe Patrick M; Knäuper Vera; Docherty Andrew J P; Becherer J David; Blobel Carl P; Murphy Gillian
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs.
FEBS letters 2002;524(1-3):154-8.
2002: Weskamp Gisela; Cai Hui; Brodie Thomas A; Higashyama Shigeki; Manova Katia; Ludwig Thomas; Blobel Carl P
Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.
Molecular and cellular biology 2002;22(5):1537-44.
2002: Blobel C P
Functional and biochemical characterization of ADAMs and their predicted role in protein ectodomain shedding.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(2):83-4.
2001: Böhm B B; Aigner T; Blobel C P; Kalden J R; Burkhardt H
Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue.
Arthritis and rheumatism 2001;44(9):2046-54.
2001: Howard L; Zheng Y; Horrocks M; Maciewicz R A; Blobel C
Catalytic activity of ADAM28.
FEBS letters 2001;498(1):82-6.
2001: Schlöndorff J; Lum L; Blobel C P
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertase.
The Journal of biological chemistry 2001;276(18):14665-74.
2000: Blobel C P
Functional processing of fertilin: evidence for a critical role of proteolysis in sperm maturation and activation.
Reviews of reproduction 2000;5(2):75-83.
2000: Howard L; Maciewicz R A; Blobel C P
Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28.
The Biochemical journal 2000;348 Pt 1():21-7.
2000: Schlöndorff J; Becherer J D; Blobel C P
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE).
The Biochemical journal 2000;347 Pt 1():131-8.
1999: Nelson K K; Schlöndorff J; Blobel C P
Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.
The Biochemical journal 1999;343 Pt 3():673-80.
1999: Schlöndorff J; Blobel C P
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding.
Journal of cell science 1999;112 ( Pt 21)():3603-17.
1999: Howard L; Nelson K K; Maciewicz R A; Blobel C P
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.
The Journal of biological chemistry 1999;274(44):31693-9.
1999: Böhm B B; Aigner T; Gehrsitz A; Blobel C P; Kalden J R; Burkhardt H
Up-regulation of MDC15 (metargidin) messenger RNA in human osteoarthritic cartilage.
Arthritis and rheumatism 1999;42(9):1946-50.
1999: Lum L; Wong B R; Josien R; Becherer J D; Erdjument-Bromage H; Schlöndorff J; Tempst P; Choi Y; Blobel C P
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival.
The Journal of biological chemistry 1999;274(19):13613-8.
1999: Roghani M; Becherer J D; Moss M L; Atherton R E; Erdjument-Bromage H; Arribas J; Blackburn R K; Weskamp G; Tempst P; Blobel C P
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.
The Journal of biological chemistry 1999;274(6):3531-40.
1998: Cai H; Krätzschmar J; Alfandari D; Hunnicutt G; Blobel C P
Neural crest-specific and general expression of distinct metalloprotease-disintegrins in early Xenopus laevis development.
Developmental biology 1998;204(2):508-24.
1998: Lum L; Reid M S; Blobel C P
Intracellular maturation of the mouse metalloprotease disintegrin MDC15.
The Journal of biological chemistry 1998;273(40):26236-47.
1998: Inoue D; Reid M; Lum L; Krätzschmar J; Weskamp G; Myung Y M; Baron R; Blobel C P
Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.
The Journal of biological chemistry 1998;273(7):4180-7.
1997: Lum L; Blobel C P
Evidence for distinct serine protease activities with a potential role in processing the sperm protein fertilin.
Developmental biology 1997;191(1):131-45.
1997: Blobel C P
Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch.
Cell 1997;90(4):589-92.
1997: Shilling F M; Krätzschmar J; Cai H; Weskamp G; Gayko U; Leibow J; Myles D G; Nuccitelli R; Blobel C P
Identification of metalloprotease/disintegrins in Xenopus laevis testis with a potential role in fertilization.
Developmental biology 1997;186(2):155-64.
1996: Krätzschmar J; Lum L; Blobel C P
Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence.
The Journal of biological chemistry 1996;271(9):4593-6.
1996: Weskamp G; Krätzschmar J; Reid M S; Blobel C P
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
The Journal of cell biology 1996;132(4):717-26.
1994: Reid M S; Blobel C P
Apexin, an acrosomal pentaxin.
The Journal of biological chemistry 1994;269(51):32615-20.
1994: Myles D G; Kimmel L H; Blobel C P; White J M; Primakoff P
Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4195-8.
1994: Weskamp G; Blobel C P
A family of cellular proteins related to snake venom disintegrins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2748-51.
1993: Wolfsberg T G; Bazan J F; Blobel C P; Myles D G; Primakoff P; White J M
The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10783-7.
1992: Blobel C P; White J M
Structure, function and evolutionary relationship of proteins containing a disintegrin domain.
Current opinion in cell biology 1992;4(5):760-5.
1992: Blobel C P; Wolfsberg T G; Turck C W; Myles D G; Primakoff P; White J M
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion.
Nature 1992;356(6366):248-52.
1990: Blobel C P; Myles D G; Primakoff P; White J M
Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.
The Journal of cell biology 1990;111(1):69-78.
1989: White J M; Blobel C P
Cell-to-cell fusion.
Current opinion in cell biology 1989;1(5):934-9.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Carl Blobel

Research Profile (preview)

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Concepts & Ideas

Anatomy

Procedures

Physiology

Phenomena

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Carl Blobel (preview)

All Publications