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Manfred Blobner

Research Profile

Chemicals & Drugs

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Neuromuscular Junction

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TOP 3
Jan Martin; Norman Moser; Manfred Blobner; Raymonde Busch; Eberhard Kochs; Peter B Luppa
Point-of-care testing on admission to the intensive care unit: lactate and glucose independently predict mortality.
Kristine Kellermann; Eberhard Kochs; Peter Luppa; Manfred Blobner; Lucia M Gordan; Bettina Jungwirth
Functional outcome in female rats after 45 minutes of deep hypothermic circulatory arrest: gender matters.
Maria Lucia Gordan; Bettina Jungwirth; Kristine Kellermann; Eberhard Kochs; frauke ohl; Manfred Blobner
Evaluation of neurobehavioral deficits following different severities of cerebral ischemia in rats: a comparison between the modified hole board test and the Morris water maze test.

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2013: Jan Martin; Norman Moser; Manfred Blobner; Raymonde Busch; Eberhard Kochs; Peter B Luppa
Point-of-care testing on admission to the intensive care unit: lactate and glucose independently predict mortality.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2013;51(2):405-12.
2013: Kristine Kellermann; Eberhard Kochs; Peter Luppa; Manfred Blobner; Lucia M Gordan; Bettina Jungwirth
Functional outcome in female rats after 45 minutes of deep hypothermic circulatory arrest: gender matters.
The Thoracic and cardiovascular surgeon 2013;61(1):52-65.
2012: Maria Lucia Gordan; Bettina Jungwirth; Kristine Kellermann; Eberhard Kochs; frauke ohl; Manfred Blobner
Evaluation of neurobehavioral deficits following different severities of cerebral ischemia in rats: a comparison between the modified hole board test and the Morris water maze test.
Behavioural brain research 2012;235(1):7-20.
2011: Bettina Jungwirth; Kristine Kellermann; Manfred Blobner; Maria L Gordan; Eberhard Kochs
Xenon administration immediately after but not before or during cardiopulmonary bypass with cerebral air embolism impairs cerebral outcome in rats.
European journal of anaesthesiology 2011;28(12):882-7.
2011: Barbara Eckel; Eberhard F Kochs; frauke ohl; Ralph Bogdanski; Manfred Blobner
Cognitive deficits after systemic induction of inducible nitric oxide synthase: a randomised trial in rats.
European journal of anaesthesiology 2011;28(9):655-63.
2011: Kristine Kellermann; Nadja Dertinger; Manfred Blobner; Frieder Kees; Eberhard Kochs; Bettina Jungwirth
Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance.
The Journal of thoracic and cardiovascular surgery 2011;141(3):796-802.
2010: Stefan J Schaller; Heidrun Fink; Kurt Ulm; Manfred Blobner
Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block.
Anesthesiology 2010;113(5):1054-60.
2010: Manfred Blobner; Lars I Eriksson; Jens Scholz; Johann Motsch; Giorgio Della Rocca; Martine E Prins
Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.
European journal of anaesthesiology 2010;27(10):874-81.
2010: M Lucia Gordan; Kristine Kellermann; Manfred Blobner; Georg Nollert; Eberhard Kochs; Bettina Jungwirth
Fast rewarming after deep hypothermic circulatory arrest in rats impairs histologic outcome and increases NFκB expression in the brain.
Perfusion 2010;25(5):349-54.
2010: C Unterbuchner; H Fink; Manfred Blobner
The use of sugammadex in a patient with myasthenia gravis.
Anaesthesia 2010;65(3):302-5.
2010: Christiane G Frick; Marc Helming; J A Jeevendra Martyn; Manfred Blobner; Heidrun Fink
Continuous administration of pyridostigmine improves immobilization-induced neuromuscular weakness.
Critical care medicine 2010;38(3):922-7.
2010: Bettina Jungwirth; Barbara Eckel; Manfred Blobner; Kristine Kellermann; Eberhard Kochs; G Burkhard Mackensen
The impact of cardiopulmonary bypass on systemic interleukin-6 release, cerebral nuclear factor-kappa B expression, and neurocognitive outcome in rats.
Anesthesia and analgesia 2010;110(2):312-20.
2010: Barbara Eckel; Martina Richtsfeld; Laura Starker; Manfred Blobner
Transgenic Alzheimer mice have a larger minimum alveolar anesthetic concentration of isoflurane than their nontransgenic littermates.
Anesthesia and analgesia 2010;110(2):438-41.
2010: Barbara Eckel; Manfred Blobner; Gerhard Rammes
Anesthetics promoting in vitro AβPP metabolism and amyloid-β toxicity.
Journal of Alzheimer's disease : JAD 2010;22 Suppl 3():21-6.
2010: Eva Eberspächer; Manfred Blobner; Christian Werner; Stefanie Ruf; Barbara Eckel; Kristin Engelhard; Wolfgang Schmahl; Adrian W Gelb
The long-term effect of four hours of hyperventilation on neurocognitive performance and lesion size after controlled cortical impact in rats.
Anesthesia and analgesia 2010;110(1):181-7.
2009: Kristine Kellermann; M Lucia Gordan; Georg Nollert; Manfred Blobner; Eberhard Kochs; Bettina Jungwirth
Long-term assessment of NFkappaB expression in the brain and neurologic outcome following deep hypothermic circulatory arrest in rats.
Perfusion 2009;24(6):429-36.
2009: Bettina Jungwirth; Kristine Kellermann; Ma Qing; G Burkhard Mackensen; Manfred Blobner; Eberhard Kochs
Cerebral tumor necrosis factor alpha expression and long-term neurocognitive performance after cardiopulmonary bypass in rats.
The Journal of thoracic and cardiovascular surgery 2009;138(4):1002-7.
2009: Vegard Dahl; Philippe E Pendeville; Markus W Hollmann; Tom Heier; Esther Am Abels; Manfred Blobner
Safety and efficacy of sugammadex for the reversal of rocuronium-induced neuromuscular blockade in cardiac patients undergoing noncardiac surgery.
European journal of anaesthesiology 2009;26(10):874-84.
2009: Philipp Fassbender; Götz Geldner; Manfred Blobner; Rainer Hofmockel; Christopher Rex; Shiva Gautam; Atul Malhotra; Matthias Eikermann
Clinical predictors of duration of action of cisatracurium and rocuronium administered long-term.
American journal of critical care : an official publication, American Association of Critical-Care Nurses 2009;18(5):439-45.
2009: Manfred Blobner
[Short acting muscle relaxants: is neuromuscular monitoring still necessary?].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2009;44(5):348-54; quiz 356, 378.
2009: Gerhard Rammes; Laura K Starker; Rainer Haseneder; Jasmin Berkmann; Alexandra Plack; Walter Zieglgänsberger; frauke ohl; Eberhard Kochs; Manfred Blobner
Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression.
Neuropharmacology 2009;56(3):626-36.
2008: Heidrun Fink; Marc Helming; Christoph Unterbuchner; Andrea Lenz; Frauke Neff; J A Jeevendra Martyn; Manfred Blobner
Systemic inflammatory response syndrome increases immobility-induced neuromuscular weakness.
Critical care medicine 2008;36(3):910-6.
2008: Christiane G Frick; Heidrun Fink; Maria L Gordan; Barbara Eckel; J A Jeevendra Martyn; Manfred Blobner
Chronic Escherichia coli infection induces muscle wasting without changing acetylcholine receptor numbers.
Intensive care medicine 2008;34(3):561-7.
2007: Bettina Jungwirth; Kristine Kellermann; Manfred Blobner; Wolfgang Schmehl; Eberhard Kochs; G Burkhard Mackensen
Cerebral air emboli differentially alter outcome after cardiopulmonary bypass in rats compared with normal circulation.
Anesthesiology 2007;107(5):768-75.
2007: Christiane G Frick; Martina Richtsfeld; Nita D Sahani; Masao Kaneki; Manfred Blobner; J A Jeevendra Martyn
Long-term effects of botulinum toxin on neuromuscular function.
Anesthesiology 2007;106(6):1139-46.
2007: Dirk M. Maybauer; Götz Geldner; Manfred Blobner; Fritz Pühringer; Rainer Hofmockel; C Rex; Hinnerk F Wulf; L H J Eberhart; C Arndt; Matthias Eikermann
Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium.
Anaesthesia 2007;62(1):12-7.
2007: Rainer Hofmockel; Birgit Pohl; Jörn Bajorat; Manfred Blobner
Onset properties of mivacurium measured by mechanomyography depend on the twitch height of the adductor pollicis muscle.
European journal of anaesthesiology 2007;24(1):82-6.
2006: R Zanner; N Moser; Manfred Blobner; Peter B Luppa
[Transport of blood gas samples: is the pneumatic tube system safe?].
Der Anaesthesist 2006;55(10):1099-104.
2006: H Fink; Götz Geldner; Thomas Fuchs-Buder; Rainer Hofmockel; K Ulm; B Wallek; Manfred Blobner
[Muscle relaxants in Germany 2005: a comparison of application customs in hospitals and private practices].
Der Anaesthesist 2006;55(6):668-78.
2006: Bettina Jungwirth; G Burkhard Mackensen; Manfred Blobner; Frauke Neff; Bruno Reichart; Eberhard Kochs; Georg Nollert
Neurologic outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats: description of a new model.
The Journal of thoracic and cardiovascular surgery 2006;131(4):805-12.
2006: Bettina Jungwirth; M Lucia Gordan; Manfred Blobner; Wolfgang Schmehl; Eberhard Kochs; G Burkhard Mackensen
Xenon impairs neurocognitive and histologic outcome after cardiopulmonary bypass combined with cerebral air embolism in rats.
Anesthesiology 2006;104(4):770-6.
2006: Matthias Eikermann; Manfred Blobner; Harald Groeben; Christopher Rex; Thomas Grote; Markus Neuhäuser; Martin Beiderlinden; Jürgen Peters
Postoperative upper airway obstruction after recovery of the train of four ratio of the adductor pollicis muscle from neuromuscular blockade.
Anesthesia and analgesia 2006;102(3):937-42.
2005: Heidrun Fink; Ralph Bogdanski; Peter B Luppa; J A Jeevendra Martyn; Manfred Blobner
Nitric oxide is not a mediator of inflammation-induced resistance to atracurium.
Anesthesia and analgesia 2005;101(5):1362-7.
2005: Götz Geldner; Manfred Blobner
GW280430A.
Anesthesiology 2005;102(4):861; author reply 862-5.
2004: Kristin Engelhard; Christian Werner; Eva Eberspächer; Monika Pape; Manfred Blobner; Peter Hutzler; Eberhard Kochs
Sevoflurane and propofol influence the expression of apoptosis-regulating proteins after cerebral ischaemia and reperfusion in rats.
European journal of anaesthesiology 2004;21(7):530-7.
2004: Heidrun Fink; Shingo Yasuhara; Manfred Blobner; J A Jeevendra Martyn
Up-regulation of acetylcholine receptors during subchronic infusion of pancuronium is caused by a posttranscriptional mechanism related to disuse.
Critical care medicine 2004;32(2):509-13.
2003: Kristin Engelhard; Christian Werner; William E Hoffman; Bianca Matthes; Manfred Blobner; Eberhard Kochs
The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
Anesthesia and analgesia 2003;97(4):1155-61, table of contents.
2003: Götz Geldner; C Lang; W Hoffmann; A Hossfeld; J Weinberger; M Eble; Manfred Blobner
[The time-course of action of rapacuronium and mivacurium after early reversal following equally lasting relaxation].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2003;38(9):594-9.
2003: Thomas Fuchs-Buder; Rainer Hofmockel; Götz Geldner; C Diefenbach; K Ulm; Manfred Blobner
[The use of neuromuscular monitoring in Germany].
Der Anaesthesist 2003;52(6):522-6.
2003: Rainer Hofmockel; Götz Geldner; C Diefenbach; Thomas Fuchs-Buder; K Ulm; Manfred Blobner
[Application of muscle relaxants for rapid-sequence induction of anaesthesia].
Der Anaesthesist 2003;52(6):516-21.
2003: Götz Geldner; Thomas Fuchs-Buder; Rainer Hofmockel; C Diefenbach; K Ulm; Manfred Blobner
[The use of muscle relaxants for routine induction of anesthesia in Germany].
Der Anaesthesist 2003;52(5):435-41.
2003: Manfred Blobner; A-M Söhnel; A van de Roemer; H Bachmann; Götz Geldner; Rainer Hofmockel; Thomas Fuchs-Buder; C Diefenbach; K Ulm
[Application of muscle relaxants in Germany. A survey of German anaesthesia departments].
Der Anaesthesist 2003;52(5):427-34.
2003: Ralph Bogdanski; Manfred Blobner; Christian Werner
Critical illness polyneuropathy and myopathy: do they persist for lifetime?
Critical care medicine 2003;31(4):1279-80.
2003: Ralph Bogdanski; Manfred Blobner; Heidrun Fink; Eberhard Kochs
Effects of xenon on mesenteric blood flow.
European journal of anaesthesiology 2003;20(2):98-103.
2003: Kristin Engelhard; Christian Werner; Eva Eberspächer; Monika Bachl; Manfred Blobner; Eberhard Hildt; Peter Hutzler; Eberhard Kochs
The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats.
Anesthesia and analgesia 2003;96(2):524-31, table of contents.
2003: Heidrun Fink; Peter B Luppa; Barbara Mayer; Hilkea Rosenbrock; Jochen Metzger; J A Jeevendra Martyn; Manfred Blobner
Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors.
Anesthesiology 2003;98(1):82-8.
2002: Kristin Engelhard; Christian Werner; Susanne Kaspar; Oliver Möllenberg; Manfred Blobner; Monika Bachl; Eberhard Kochs
Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
Anesthesiology 2002;96(2):450-7.
2001: B Mayer; Heidrun Fink; Ralph Bogdanski; Josef Stadler; Manfred Blobner
Inflammatory liver disease shortens atracurium-induced neuromuscular blockade in rats.
European journal of anaesthesiology 2001;18(9):599-604.
2001: Manfred Blobner; R Mann
[Anesthesia in patients with myasthenia gravis].
Der Anaesthesist 2001;50(7):484-93.
2001: F Hänel; Manfred Blobner; Ralph Bogdanski; C Werner
Effects of carbon dioxide pneumoperitoneum on cerebral hemodynamics in pigs.
Journal of neurosurgical anesthesiology 2001;13(3):222-6.
2001: Jochen Metzger; Manfred Blobner; Peter B Luppa
Sensitive chemiluminescence immunoassay for the determination of rat serum alpha1-acid glycoprotein.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2001;39(6):514-8.
2001: Thomas Frietsch; Ralph Bogdanski; Manfred Blobner; C Werner; Wolfgang Kuschinsky; Klaus F Waschke
Effects of xenon on cerebral blood flow and cerebral glucose utilization in rats.
Anesthesiology 2001;94(2):290-7.
2000: Ralph Bogdanski; Manfred Blobner; I Becker; F Hänel; Heidrun Fink; Eberhard Kochs
Cerebral histopathology following portal venous infusion of bacteria in a chronic porcine model.
Anesthesiology 2000;93(3):793-804.
2000: R Mann; Manfred Blobner; S Jelen-Esselborn; R Busley; Christian Werner
Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients.
Anesthesiology 2000;93(2):346-50.
2000: H Fink; Manfred Blobner
[Neuropathies: the effect of relaxography and neuromuscular function].
Der Anaesthesist 2000;49 Suppl 1():S29-32.
2000: R Mann; Manfred Blobner
[Neuromuscular monitoring in myasthenia gravis].
Der Anaesthesist 2000;49 Suppl 1():S26-8.
2000: Heidrun Fink; Manfred Blobner; Ralph Bogdanski; F Hänel; C Werner; Eberhard Kochs
Effects of xenon on cerebral blood flow and autoregulation: an experimental study in pigs.
British journal of anaesthesia 2000;84(2):221-5.
2000: R Busley; Manfred Blobner; Eberhard Kochs
[Rapacuronium: a new, non-depolarizing muscle relaxant for rapid intubation?].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2000;35(2):112-4.
2000: Manfred Blobner; R Busley; Eberhard Kochs
[Rapid sequence induction with succinylcholine: an option to reduce side effects].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2000;35(2):108-10.
1999: Manfred Blobner; R Busley; R Mann; S Jelen-Esselborn; Eberhard Kochs
[Neuromuscular recovery following mivacurium is predictable in patients with severe systemic disease prognoses].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1999;34(10):638-41.
1999: Manfred Blobner; Eberhard Kochs; Heidrun Fink; B Mayer; A Veihelmann; T Brill; Josef Stadler
Pharmacokinetics and pharmacodynamics of vecuronium in rats with systemic inflammatory response syndrome: treatment with NG-monomethyl-L-arginine.
Anesthesiology 1999;91(4):999-1005.
1999: Ralph Bogdanski; Manfred Blobner; F Hänel; Eberhard Kochs
[Septic encephalopathy].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1999;34(3):123-30.
1999: Manfred Blobner; Ralph Bogdanski; S Jelen-Esselborn; J Henke; W Erhard; Eberhard Kochs
[Visceral resorption of intra-abdominal insufflated carbon dioxide in swine].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1999;34(2):94-9.
1998: Michaela Scheller; Manfred Blobner; C Von Loewenich; HJ Schneck; Josef Stadler; C Franke; Eberhard Kochs
The NO synthase inhibitors L-Name and L-NMMA, but not L-arginine, block the mammalian nicotinic acetylcholine receptor channel.
Toxicology letters 1998;100-101():109-13.
1998: Manfred Blobner; Ralph Bogdanski; Eberhard Kochs; J Henke; A Findeis; S Jelen-Esselborn
Effects of intraabdominally insufflated carbon dioxide and elevated intraabdominal pressure on splanchnic circulation: an experimental study in pigs.
Anesthesiology 1998;89(2):475-82.
1997: R Probst; Manfred Blobner; Peter B Luppa; Dieter Neumeier
Quantification of the neuromuscular blocking agent rocuronium and its putative metabolite 17-desacetylrocuronium in heparinized plasma by capillary gas chromatography using a nitrogen sensitive detector.
Journal of chromatography. B, Biomedical sciences and applications 1997;702(1-2):111-7.
1997: A Veihelmann; T Brill; Manfred Blobner; I Scheller; B Mayer; M Prölls; Sigrid Himpel; Josef Stadler
Inhibition of nitric oxide synthesis improves detoxication in inflammatory liver dysfunction in vivo.
The American journal of physiology 1997;273(2 Pt 1):G530-6.
1996: Manfred Blobner; S Jelen-Esselborn; R Mann; M Kling; G Schneider; HJ Schneck; Eberhard Kochs
[Neuromuscular and cardiovascular effect of mivacurium in anesthesia induction in patients with renal failure].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1996;31(1):15-21.
1995: Manfred Blobner; S Jelen-Esselborn; G Schneider; R Mann; M Kling; Peter B Luppa; HJ Schneck; Eberhard Kochs
Effect of renal function on neuromuscular block induced by continuous infusion of mivacurium.
British journal of anaesthesia 1995;74(4):452-4.
1994: Manfred Blobner; A R Felber; P Hösl; S Gögler; HJ Schneck; S Jelen-Esselborn
[Effect of capnoperitoneum on postoperative carbon dioxide homeostasis].
Der Anaesthesist 1994;43(11):718-22.
1994: Manfred Blobner; A R Felber; HJ Schneck; S Jelen-Esselborn
[Dose-response relationship of atracurium in underweight, normal and overweight patients].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1994;29(6):338-42.
1994: Manfred Blobner; HJ Schneck; A R Felber; S Goegler; H Feussner; S Jelen-Esselborn
[Comparative study of the recovery phase. Laparoscopic cholecystectomy following isoflurane, methohexital and propofol anesthesia].
Der Anaesthesist 1994;43(9):573-81.
1993: Manfred Blobner; A R Felber; S Gögler; H Feussner; E M Weigl; G Jelen; S Jelen-Esselborn
[The resorption of carbon dioxide from the pneumoperitoneum in laparoscopic cholecystectomy].
Der Anaesthesist 1993;42(5):288-94.
1993: Manfred Blobner; A R Felber; G Jelen; S Gögler; S Jelen-Esselborn
[Anesthesia for renal transplantation: continuous neuromuscular blockade with atracurium and the management of intraoperative hypertension with nifedipine].
Anaesthesiologie und Reanimation 1993;18(4):92-4, 97-9.
1992: S Jelen-Esselborn; Manfred Blobner; J Hölzl; A R Felber
[Nifedipine prolongs a neuromuscular blockade caused by atracurium].
Anaesthesiologie und Reanimation 1992;17(4):195-205.
1990: S Jelen-Esselborn; Manfred Blobner
[Potentiation of nondepolarizing muscle relaxants by nifedipine iv in inhalation anesthesia].
Der Anaesthesist 1990;39(3):173-8.