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Patrick Sheets

Research Profile

Chemicals & Drugs

Physiology

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Publications

TOP 3
Matthew K Brittain; Joel M Brittain; Tatiana Brustovetsky; Theodore R Cummins; Rajesh Khanna; Patrick L Sheets; Nickolay Brustovetsky
Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger.
Patrick L Sheets; brian jarecki; Theodore R Cummins
Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels.
brian jarecki; Patrick L Sheets; Yucheng Xiao; James O Jackson; Theodore R Cummins
Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.

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All Publications

2012: Matthew K Brittain; Joel M Brittain; Tatiana Brustovetsky; Theodore R Cummins; Rajesh Khanna; Patrick L Sheets; Nickolay Brustovetsky
Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger.
Neurobiology of disease 2012;46(1):109-17.
2011: Patrick L Sheets; brian jarecki; Theodore R Cummins
Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels.
British journal of pharmacology 2011;164(2b):719-30.
2009: brian jarecki; Patrick L Sheets; Yucheng Xiao; James O Jackson; Theodore R Cummins
Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.
Channels (Austin, Tex.) 2009;3(4):259-67.
2008: brian jarecki; Patrick L Sheets; James O Jackson; Theodore R Cummins
Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation.
The Journal of physiology 2008;586(Pt 17):4137-53.
2008: Patrick L Sheets; Cara Heers; Thomas Stoehr; Theodore R Cummins
Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine.
The Journal of pharmacology and experimental therapeutics 2008;326(1):89-99.
2008: Takako Kondo; Patrick L Sheets; David A Zopf; Heather L Aloor; Theodore R Cummins; Rebecca J Chan; Eri Hashino
Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(15):5780-5.
2007: Theodore R Cummins; Patrick L Sheets; Stephen G Waxman
The roles of sodium channels in nociception: Implications for mechanisms of pain.
Pain 2007;131(3):243-57.
2007: Patrick L Sheets; James O Jackson; Stephen G Waxman; Sulayman D Dib-Hajj; Theodore R Cummins
A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
The Journal of physiology 2007;581(Pt 3):1019-31.
2006: Patrick L Sheets; Peter Gerner; Chi-Fei Wang; Sho-Ya Wang; Ging Kuo Wang; Theodore R Cummins
Inhibition of Nav1.7 and Nav1.4 sodium channels by trifluoperazine involves the local anesthetic receptor.
Journal of neurophysiology 2006;96(4):1848-59.