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Margaret Sheil

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Protein Binding

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Stephen J Watt; Margaret M Sheil; Jennifer L Beck; Pavel Prosselkov; Gottfried Otting; Nicholas E Dixon
Effect of protein stabilization on charge state distribution in positive- and negative-ion electrospray ionization mass spectra.
Stephen J Watt; Thitima Urathamakul; Patrick M Schaeffer; Neal K Williams; Margaret M Sheil; Nicholas E Dixon; Jennifer L Beck
Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry.
Michael J Hannon; Philip S Green; Dianne M Fisher; Peter J Derrick; Jennifer L Beck; Stephen J Watt; Stephen F Ralph; Margaret M Sheil; Philip R Barker; Nathaniel W Alcock; Robert J Price; Karen J Sanders; Richard Pither; Julie Davis; Alison Rodger
An estrogen-platinum terpyridine conjugate: DNA and protein binding and cellular delivery.

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All Publications

2007: Stephen J Watt; Margaret M Sheil; Jennifer L Beck; Pavel Prosselkov; Gottfried Otting; Nicholas E Dixon
Effect of protein stabilization on charge state distribution in positive- and negative-ion electrospray ionization mass spectra.
Journal of the American Society for Mass Spectrometry 2007;18(9):1605-11.
2007: Stephen J Watt; Thitima Urathamakul; Patrick M Schaeffer; Neal K Williams; Margaret M Sheil; Nicholas E Dixon; Jennifer L Beck
Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry.
Rapid communications in mass spectrometry : RCM 2007;21(2):132-40.
2006: Michael J Hannon; Philip S Green; Dianne M Fisher; Peter J Derrick; Jennifer L Beck; Stephen J Watt; Stephen F Ralph; Margaret M Sheil; Philip R Barker; Nathaniel W Alcock; Robert J Price; Karen J Sanders; Richard Pither; Julie Davis; Alison Rodger
An estrogen-platinum terpyridine conjugate: DNA and protein binding and cellular delivery.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(31):8000-13.
2006: Jennifer L Beck; Thitima Urathamakul; Stephen J Watt; Margaret M Sheil; Patrick M Schaeffer; Nicholas E Dixon
Proteomic dissection of DNA polymerization.
Expert review of proteomics 2006;3(2):197-211.
2005: Rajesh Gupta; Jennifer L Beck; Margaret M Sheil; Stephen F Ralph
Identification of bifunctional GA and AG intrastrand crosslinks formed between cisplatin and DNA.
Journal of inorganic biochemistry 2005;99(2):552-9.
2005: Stephen J Watt; Aaron Oakley; Margaret M Sheil; Jennifer L Beck
Comparison of negative and positive ion electrospray ionization mass spectra of calmodulin and its complex with trifluoperazine.
Rapid communications in mass spectrometry : RCM 2005;19(15):2123-30.
2004: Rajesh Gupta; Samir M Hamdan; Nicholas E Dixon; Margaret M Sheil; Jennifer L Beck
Application of electrospray ionization mass spectrometry to study the hydrophobic interaction between the epsilon and theta subunits of DNA polymerase III.
Protein science : a publication of the Protein Society 2004;13(11):2878-87.
2004: Renata L A Furlan; Stephen J Watt; Leandro M Garrido; Gustavo Amarante-Mendes; Mohammad Nur-e-Alam; Jürgen Rohr; Alfredo F Braña; Carmen Mendez; José A Salas; Margaret M Sheil; Jennifer L Beck; Gabriel Padilla
DNA-binding properties of cosmomycin D, an anthracycline with two trisaccharide chains.
The Journal of antibiotics 2004;57(10):647-54.
2004: Rajesh Gupta; Jennifer L Beck; Stephen F Ralph; Margaret M Sheil; Janice R Aldrich-Wright
Comparison of the binding stoichiometries of positively charged DNA-binding drugs using positive and negative ion electrospray ionization mass spectrometry.
Journal of the American Society for Mass Spectrometry 2004;15(10):1382-91.
2004: Thitima Urathamakul; Jennifer L Beck; Margaret M Sheil; Janice R Aldrich-Wright; Stephen F Ralph
A mass spectrometric investigation of non-covalent interactions between ruthenium complexes and DNA.
Dalton transactions (Cambridge, England : 2003) 2004;(17):2683-90.
2004: Santiago Vazquez; Nicole R Parker; Margaret M Sheil; Roger J W Truscott
Protein-bound kynurenine decreases with the progression of age-related nuclear cataract.
Investigative ophthalmology & visual science 2004;45(3):879-83.
2004: Jennifer L Beck; Shanika Ambahera; Sarah R Yong; Margaret M Sheil; John de Jersey; Stephen F Ralph
Direct observation of covalent adducts with Cys34 of human serum albumin using mass spectrometry.
Analytical biochemistry 2004;325(2):326-36.
2003: Jennifer L Beck; Rajesh Gupta; Thitima Urathamakul; Nyree L Williamson; Margaret M Sheil; Janice R Aldrich-Wright; Stephen F Ralph
Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry.
Chemical communications (Cambridge, England) 2003;(5):626-7.
2002: Michelle Colgrave; Jennifer L Beck; Margaret M Sheil; Mark S Searle
Electrospray ionisation mass spectrometric detection of weak non-covalent interactions in nogalamycin-DNA complexes.
Chemical communications (Cambridge, England) 2002;(6):556-7.
2002: Santiago Vazquez; J Andrew Aquilina; Joanne F Jamie; Margaret M Sheil; Roger J W Truscott
Novel protein modification by kynurenine in human lenses.
The Journal of biological chemistry 2002;277(7):4867-73.
2002: Amit Kapur; Jennifer L Beck; Susan E Brown; Nicholas E Dixon; Margaret M Sheil
Use of electrospray ionization mass spectrometry to study binding interactions between a replication terminator protein and DNA.
Protein science : a publication of the Protein Society 2002;11(1):147-57.
2001: Santiago Vazquez; Roger J W Truscott; R A O'Hair; A Weimann; Margaret M Sheil
A study of kynurenine fragmentation using electrospray tandem mass spectrometry.
Journal of the American Society for Mass Spectrometry 2001;12(7):786-94.
2001: Jennifer L Beck; Michelle Colgrave; Stephen F Ralph; Margaret M Sheil
Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins.
Mass spectrometry reviews 2001;20(2):61-87.
2001: Rajesh Gupta; Amit Kapur; Jennifer L Beck; Margaret M Sheil
Positive ion electrospray ionization mass spectrometry of double-stranded DNA/drug complexes.
Rapid communications in mass spectrometry : RCM 2001;15(24):2472-80.
2000: P Iannitti-Tito; A Weimann; G Wickham; Margaret M Sheil
Structural analysis of drug-DNA adducts by tandem mass spectrometry.
The Analyst 2000;125(4):627-33.
2000: Santiago Vazquez; B Garner; Margaret M Sheil; Roger J W Truscott
Characterisation of the major autoxidation products of 3-hydroxykynurenine under physiological conditions.
Free radical research 2000;32(1):11-23.
1999: Amit Kapur; Jennifer L Beck; Margaret M Sheil
Observation of daunomycin and nogalamycin complexes with duplex DNA using electrospray ionisation mass spectrometry.
Rapid communications in mass spectrometry : RCM 1999;13(24):2489-97.
1997: R Blakytny; J A Carver; John J Harding; G W Kilby; Margaret M Sheil
A spectroscopic study of glycated bovine alpha-crystallin: investigation of flexibility of the C-terminal extension, chaperone activity and evidence for diglycation.
Biochimica et biophysica acta 1997;1343(2):299-315.
1997: G W Kilby; Margaret M Sheil; D Shaw; John J Harding; Roger J W Truscott
Amino acid sequence of bovine gamma E (IVa) lens crystallin.
Protein science : a publication of the Protein Society 1997;6(4):909-12.
1997: Keiryn Bennett; S V Smith; Roger J W Truscott; Margaret M Sheil
Monitoring papain digestion of a monoclonal antibody by electrospray ionization mass spectrometry.
Analytical biochemistry 1997;245(1):17-27.
1996: R I Mar; John A Carver; Margaret M Sheil; J Boschenok; S Fu; D C Shaw
Primary structure of trypsin inhibitors from Sicyos australis.
Phytochemistry 1996;41(5):1265-74.
1996: M L Riley; John J Harding; G W Kilby; Roger J W Truscott; A Aquilina; Margaret M Sheil
Molecular masses of gamma-crystallins.
Ophthalmic research 1996;28 Suppl 2():131-5.
1996: Keiryn Bennett; S V Smith; R M Lambrecht; Roger J W Truscott; Margaret M Sheil
Rapid characterization of chemically-modified proteins by electrospray mass spectrometry.
Bioconjugate chemistry 1996;7(1):16-22.
1996: J Boschenok; Margaret M Sheil
Electrospray tandem mass spectrometry of nucleotides.
Rapid communications in mass spectrometry : RCM 1996;10(1):144-9.
1996: G W Kilby; Roger J W Truscott; G M Stuchbury; Margaret M Sheil
Mass spectrometry of lens crystallins: bovine beta-crystallins.
Rapid communications in mass spectrometry : RCM 1996;10(1):123-9.
1995: S Fu; L A Hick; Margaret M Sheil; Roger T Dean
Structural identification of valine hydroperoxides and hydroxides on radical-damaged amino acid, peptide, and protein molecules.
Free radical biology & medicine 1995;19(3):281-92.
1995: G W Kilby; John A Carver; J L Zhu; Margaret M Sheil; Roger J W Truscott
Loss of the C-terminal serine residue from bovine beta B2-crystallin.
Experimental eye research 1995;60(5):465-9.
1995: G Wickham; P Iannitti; J Boschenok; Margaret M Sheil
The observation of a hedamycin-d(CACGTG)2 covalent adduct by electrospray mass spectrometry.
FEBS letters 1995;360(3):231-4.
1995: G Wickham; P Iannitti; J Boschenok; Margaret M Sheil
Electrospray ionization mass spectrometry of covalent ligand-oligonucleotide adducts: evidence for specific duplex ion formation.
Rapid communications in mass spectrometry : RCM 1995;Spec No():S197-203.
1994: Roger J W Truscott; A M Wood; John A Carver; Margaret M Sheil; G M Stutchbury; J Zhu; G W Kilby
A new UV-filter compound in human lenses.
FEBS letters 1994;348(2):173-6.
1992: R A O'Hair; Margaret M Sheil; Roger J W Truscott
Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction.
Ophthalmic research 1992;24(5):303-7.