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Edward Block

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Anatomy

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Co-Publications
Name
48
Patel, Jawaharlal
15
Zhang, Jianliang
13
Zharikov, Sergey
13
Su, Yunchao
10
Li, Yong
6
Hu, Hanbo
4
Raizada, Mohan
4
Krotova, Karina
3
Kilberg, Michael
3
Kondrikov, Dmitry
3
Johnson, Richard
3
Belayev, Leonid
3
Cui, Zhaoqiang
3
Li, Liuzhe
3
Xia, Shen-Ling

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Publications

TOP 3
Hu Hanbo; Lu Li; Mu Wei; Johnson Richard J; Block Edward R; Patel Jawaharlal M
Priming donor lungs with thioredoxin-1 attenuates acute allograft injury in a rat model of lung transplantation.
Patel Jawaharlal M; Hu Hanbo; Lu Li; Deem Amy; Akindipe Olufemi; Brantly Mark; Block Edward R; Antony Veena B; Baz Maher A
Thioredoxin as a biomarker for graft rejection in lung transplant recipients.
Li Liuzhe; Zhang Jianliang; Jin Bilian; Block Edward R; Patel Jawaharlal M
Nitric oxide upregulation of caspase-8 mRNA expression in lung endothelial cells: role of JAK2/STAT-1 signaling.

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All Publications

2008: Hu Hanbo; Lu Li; Mu Wei; Johnson Richard J; Block Edward R; Patel Jawaharlal M
Priming donor lungs with thioredoxin-1 attenuates acute allograft injury in a rat model of lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008;27(10):1142-9.
2008: Patel Jawaharlal M; Hu Hanbo; Lu Li; Deem Amy; Akindipe Olufemi; Brantly Mark; Block Edward R; Antony Veena B; Baz Maher A
Thioredoxin as a biomarker for graft rejection in lung transplant recipients.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(5):486-95.
2007: Li Liuzhe; Zhang Jianliang; Jin Bilian; Block Edward R; Patel Jawaharlal M
Nitric oxide upregulation of caspase-8 mRNA expression in lung endothelial cells: role of JAK2/STAT-1 signaling.
Molecular and cellular biochemistry 2007;305(1-2):71-7.
2007: Su Yunchao; Kondrikov Dmitry; Block Edward R
Beta-actin: a regulator of NOS-3.
Science's STKE : signal transduction knowledge environment 2007;2007(404):pe52.
2006: Qiu Kai; Su Yunchao; Block Edward R
Use of recombinant calpain-2 siRNA adenovirus to assess calpain-2 modulation of lung endothelial cell migration and proliferation.
Molecular and cellular biochemistry 2006;292(1-2):69-78.
2006: Su Yunchao; Cui Zhaoqiang; Li Zhaozhong; Block Edward R
Calpain-2 regulation of VEGF-mediated angiogenesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1443-51.
2006: Krotova Karina; Hu Hanbo; Xia Shen-Ling; Belayev Leonid; Patel Jawaharlal M; Block Edward R; Zharikov Sergey
Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation.
British journal of pharmacology 2006;148(5):732-40.
2006: Nakagawa Takahiko; Hu Hanbo; Zharikov Sergey; Tuttle Katherine R; Short Robert A; Glushakova Olena; Ouyang Xiaosen; Feig Daniel I; Block Edward R; Herrera-Acosta Jaime; Patel Jawaharlal M; Johnson Richard J
A causal role for uric acid in fructose-induced metabolic syndrome.
American journal of physiology. Renal physiology 2006;290(3):F625-31.
2006: Kondrikov Dmitry; Han Hye-Rim; Block Edward R; Su Yunchao
Growth and density-dependent regulation of NO synthase by the actin cytoskeleton in pulmonary artery endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L41-50.
2005: Cui Zhaoqiang; Han Zhaosheng; Li Zhaozhong; Hu Hanbo; Patel Jawaharlal M; Antony Veena; Block Edward R; Su Yunchao
Involvement of calpain-calpastatin in cigarette smoke-induced inhibition of lung endothelial nitric oxide synthase.
American journal of respiratory cell and molecular biology 2005;33(5):513-20.
2005: Lu Jianghua; Zhang Jianalian; Block Edward R; Patel Jawaharlal M
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells.
Molecular and cellular biochemistry 2005;275(1-2):181-8.
2005: Khosla Uday M; Zharikov Sergey; Finch Jennifer L; Nakagawa Takahiko; Roncal Carlos; Mu Wei; Krotova Karina; Block Edward R; Prabhakar Sharma; Johnson Richard J
Hyperuricemia induces endothelial dysfunction.
Kidney international 2005;67(5):1739-42.
2005: Zhang Jianliang; Jin Bilian; Li Liuzhe; Block Edward R; Patel Jawaharlal M
Nitric oxide-induced persistent inhibition and nitrosylation of active site cysteine residues of mitochondrial cytochrome-c oxidase in lung endothelial cells.
American journal of physiology. Cell physiology 2005;288(4):C840-9.
2005: Cui Zhaoqiang; Zharikov Sergey; Xia Shen-Ling; Anderson Susan I; Law Andy S; Archibald Alan L; Block Edward R
Molecular cloning, characterization, and chromosomal assignment of porcine cationic amino acid transporter-1.
Genomics 2005;85(3):352-9.
2005: Su Yunchao; Kondrikov Dmitry; Block Edward R
Cytoskeletal regulation of nitric oxide synthase.
Cell biochemistry and biophysics 2005;43(3):439-49.
2004: Li Liuzhe; Zhang Jianliang; Block Edward R; Patel Jawaharlal M
Nitric oxide-modulated marker gene expression of signal transduction pathways in lung endothelial cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2004;11(4):290-7.
2004: Su Yunchao; Cao Wengang; Han Zhaosheng; Block Edward R
Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: the role of calpain.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L794-800.
2004: Hu Hanbo; Xin Meiguo; Belayev Leonid L; Zhang Jianliang; Block Edward R; Patel Jawaharlal M
Autoinhibitory domain fragment of endothelial NOS enhances pulmonary artery vasorelaxation by the NO-cGMP pathway.
American journal of physiology. Lung cellular and molecular physiology 2004;286(5):L1066-74.
2004: Zharikov Sergey I; Krotova Karina Y; Belayev Leonid; Block Edward R
Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-alpha activity.
American journal of physiology. Lung cellular and molecular physiology 2004;286(5):L974-83.
2003: Kahlos Katriina; Zhang Jianliang; Block Edward R; Patel Jawaharlal M
Thioredoxin restores nitric oxide-induced inhibition of protein kinase C activity in lung endothelial cells.
Molecular and cellular biochemistry 2003;254(1-2):47-54.
2003: Xin Mei-Guo; Zhang Jianliang; Block Edward R; Patel Jawaharlal M
Senescence-enhanced oxidative stress is associated with deficiency of mitochondrial cytochrome c oxidase in vascular endothelial cells.
Mechanisms of ageing and development 2003;124(8-9):911-9.
2003: Su Yunchao; Edwards-Bennett Sophia; Bubb Michael R; Block Edward R
Regulation of endothelial nitric oxide synthase by the actin cytoskeleton.
American journal of physiology. Cell physiology 2003;284(6):C1542-9.
2003: Krotova Karina Y; Zharikov Sergey I; Block Edward R
Classical isoforms of PKC as regulators of CAT-1 transporter activity in pulmonary artery endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L1037-44.
2002: Zhang Jianliang; Xia Shen-Ling; Block Edward R; Patel Jawaharlal M
NO upregulation of a cyclic nucleotide-gated channel contributes to calcium elevation in endothelial cells.
American journal of physiology. Cell physiology 2002;283(4):C1080-9.
2002: Li Yong D; Block Edward R; Patel Jawaharlal M
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.
American journal of physiology. Lung cellular and molecular physiology 2002;283(4):L707-16.
2002: Zhang Jianliang; Block Edward R; Patel Jawaharlal M
Down-regulation of mitochondrial cytochrome c oxidase in senescent porcine pulmonary artery endothelial cells.
Mechanisms of ageing and development 2002;123(10):1363-74.
2002: Su Yunchao; Zharikov Sergei I; Block Edward R
Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1183-9.
2002: Zhang Jianliang; Patel Jawaharlal M; Block Edward R
Enhanced apoptosis in prolonged cultures of senescent porcine pulmonary artery endothelial cells.
Mechanisms of ageing and development 2002;123(6):613-25.
2002: Zharikova Alevtina; Zharikov Sergey; Block Edward R; Prokai Laszlo
Metabolism of dynorphins by peptidases of pulmonary artery endothelial cells.
Endothelium : journal of endothelial cell research 2002;9(1):37-44.
2001: Zharikov S I; Sigova A A; Chen S; Bubb M R; Block E R
Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L465-73.
2000: Chen S; Patel J M; Block E R
Angiotensin IV-mediated pulmonary artery vasorelaxation is due to endothelial intracellular calcium release.
American journal of physiology. Lung cellular and molecular physiology 2000;279(5):L849-56.
2000: Su Y; Block E R
Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2000;278(6):L1204-12.
2000: Su Y; Block E R
Phenylarsine oxide inhibits nitric oxide synthase in pulmonary artery endothelial cells.
Free radical biology & medicine 2000;28(2):167-73.
2000: Zharikov S I; Block E R
Association of L-arginine transporters with fodrin: implications for hypoxic inhibition of arginine uptake.
American journal of physiology. Lung cellular and molecular physiology 2000;278(1):L111-7.
1999: Patel J M; Li Y D; Zhang J; Gelband C H; Raizada M K; Block E R
Increased expression of calreticulin is linked to ANG IV-mediated activation of lung endothelial NOS.
The American journal of physiology 1999;277(4 Pt 1):L794-801.
1999: Zhang J; Velsor L W; Patel J M; Postlethwait E M; Block E R
Nitric oxide-induced reduction of lung cell and whole lung thioredoxin expression is regulated by NF-kappaB.
The American journal of physiology 1999;277(4 Pt 1):L787-93.
1999: Hill-Kapturczak N; Kapturczak M H; Block E R; Patel J M; Malinski T; Madsen K M; Tisher C C
Angiotensin II-stimulated nitric oxide release from porcine pulmonary endothelium is mediated by angiotensin IV.
Journal of the American Society of Nephrology : JASN 1999;10(3):481-91.
1998: Patel J M; Martens J R; Li Y D; Gelband C H; Raizada M K; Block E R
Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation.
The American journal of physiology 1998;275(6 Pt 1):L1061-8.
1998: Su Y; Han W; Giraldo C; De Li Y; Block E R
Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells.
American journal of respiratory cell and molecular biology 1998;19(5):819-25.
1998: Zhang J; Patel J M; Block E R
Hypoxia-specific upregulation of calpain activity and gene expression in pulmonary artery endothelial cells.
The American journal of physiology 1998;275(3 Pt 1):L461-8.
1998: Zhang J; Li Y D; Patel J M; Block E R
Thioredoxin overexpression prevents NO-induced reduction of NO synthase activity in lung endothelial cells.
The American journal of physiology 1998;275(2 Pt 1):L288-93.
1998: Zharikov S I; Block E R
Characterization of L-arginine uptake by plasma membrane vesicles isolated from cultured pulmonary artery endothelial cells.
Biochimica et biophysica acta 1998;1369(1):173-83.
1997: McDonald K K; Zharikov S; Block E R; Kilberg M S
A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox".
The Journal of biological chemistry 1997;272(50):31213-6.
1997: Su Y; Block E R
Hypoxia inhibits the induction of argininosuccinate synthetase by endotoxin in lung endothelial cells.
The American journal of physiology 1997;272(5 Pt 1):L934-8.
1997: Zhang J; Patel J M; Li Y D; Block E R
Proinflammatory cytokines downregulate gene expression and activity of constitutive nitric oxide synthase in porcine pulmonary artery endothelial cells.
Research communications in molecular pathology and pharmacology 1997;96(1):71-87.
1997: Zhang J; Patel J M; Block E R
Molecular cloning, characterization and expression of a nitric oxide synthase from porcine pulmonary artery endothelial cells.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1997;116(4):485-91.
1997: McDonald K K; Rouhani R; Handlogten M E; Block E R; Griffith O W; Allison R D; Kilberg M S
Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase.
Biochimica et biophysica acta 1997;1324(1):133-41.
1997: Zharikov S I; Herrera H; Block E R
Role of membrane potential in hypoxic inhibition of L-arginine uptake by lung endothelial cells.
The American journal of physiology 1997;272(1 Pt 1):L78-84.
1997: Su Y; Couch M; Block E R
Substrate inhibition of nitric oxide synthase in pulmonary artery endothelial cells in culture.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(6):469-75.
1997: Li Y D; Patel J M; Zhang J; Block E R
Overexpression of plasma membrane annexin II in NO2-exposed pulmonary artery endothelial cells.
Free radical biology & medicine 1997;23(1):120-6.
1996: Patel J M; Zhang J; Block E R
Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity.
American journal of respiratory cell and molecular biology 1996;15(3):410-9.
1996: Zhang J L; Patel J M; Li Y D; Block E R
Reductase domain cysteines 1048 and 1114 are critical for catalytic activity of human endothelial cell nitric oxide synthase as probed by site-directed mutagenesis.
Biochemical and biophysical research communications 1996;226(1):293-300.
1996: Li Y D; Patel J M; Block E R
NO2-induced expression of specific protein kinase C isoforms and generation of phosphatidylcholine-derived diacylglycerol in cultured pulmonary artery endothelial cells.
FEBS letters 1996;389(2):131-5.
1996: Su Y; Block E R
Acute hypoxia increases intracellular L-arginine content in cultured porcine pulmonary artery endothelial cells.
Journal of cellular physiology 1996;167(2):349-53.
1996: Li Y D; Patel J M; Block E R
Nitrogen dioxide-induced expression of a 78 kDa protein in pulmonary artery endothelial cells.
Free radical biology & medicine 1996;21(2):163-71.
1995: Block E R; Herrera H; Couch M
Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells.
The American journal of physiology 1995;269(5 Pt 1):L574-80.
1995: Patel J M; Block E R
Sulfhydryl-disulfide modulation and the role of disulfide oxidoreductases in regulation of the catalytic activity of nitric oxide synthase in pulmonary artery endothelial cells.
American journal of respiratory cell and molecular biology 1995;13(3):352-9.
1995: Yang W; Block E R
Effect of hypoxia and reoxygenation on the formation and release of reactive oxygen species by porcine pulmonary artery endothelial cells.
Journal of cellular physiology 1995;164(2):414-23.
1994: Li Y D; Patel J M; Block E R
Nitrogen dioxide-induced phosphatidylserine biosynthesis and subcellular translocation in cultured pulmonary artery endothelial cells.
Toxicology and applied pharmacology 1994;129(1):114-20.
1994: Visner G A; Staples E D; Chesrown S E; Block E R; Zander D S; Nick H S
Isolation and maintenance of human pulmonary artery endothelial cells in culture isolated from transplant donors.
The American journal of physiology 1994;267(4 Pt 1):L406-13.
1994: Rao U J; Denslow N D; Block E R
Hypoxia induces the synthesis of tropomyosin in cultured porcine pulmonary artery endothelial cells.
The American journal of physiology 1994;267(3 Pt 1):L271-81.
1994: Woodard M H; Dunn W A; Laine R O; Malandro M; McMahon R; Simell O; Block E R; Kilberg M S
Plasma membrane clustering of system y+ (CAT-1) amino acid transporter as detected by immunohistochemistry.
The American journal of physiology 1994;266(5 Pt 1):E817-24.
1993: Patel J M; Block E R
Acrolein-induced injury to cultured pulmonary artery endothelial cells.
Toxicology and applied pharmacology 1993;122(1):46-53.
1992: Hart C M; Tolson J K; Block E R
Quantitative fatty acid analyses in cultured porcine pulmonary artery endothelial cells: the combined effects of fatty acid supplementation and oxidant exposure.
Journal of cellular physiology 1992;153(1):76-87.
1992: Bhat G B; Block E R
Serotonin transport in reconstituted endothelial cell plasma membrane proteoliposomes: effect of hypoxia.
American journal of respiratory cell and molecular biology 1992;6(6):633-8.
1992: Bhat G B; Block E R
Effect of hypoxia on phospholipid metabolism in porcine pulmonary artery endothelial cells.
The American journal of physiology 1992;262(5 Pt 1):L606-13.
1992: Bhat G B; Tinsley S B; Tolson J K; Patel J M; Block E R
Hypoxia increases the susceptibility of pulmonary artery endothelial cells to hydrogen peroxide injury.
Journal of cellular physiology 1992;151(2):228-38.
1992: Patel J M; Sekharam K M; Block E R
Oxidant and angiotensin II-induced subcellular translocation of protein kinase C in pulmonary artery endothelial cells.
Journal of biochemical toxicology 1992;7(2):117-23.
1991: Patel J M; Sekharam K M; Block E R
Angiotensin receptor-mediated stimulation of diacylglycerol production in pulmonary artery endothelial cells.
American journal of respiratory cell and molecular biology 1991;5(4):321-7.
1991: Patel J M; Sekharam M; Block E R
Vitamin E distribution and modulation of the physical state and function of pulmonary endothelial cell membranes.
Experimental lung research 1991;17(4):707-23.
1991: Hart C M; Tolson J K; Block E R
Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells.
The American journal of physiology 1991;260(6 Pt 1):L481-8.
1991: Visner G A; Block E R; Burr I M; Nick H S
Regulation of manganese superoxide dismutase in porcine pulmonary artery endothelial cells.
The American journal of physiology 1991;260(6 Pt 1):L444-9.
1991: Herskowitz K; Bode B P; Block E R; Souba W W
The effects of endotoxin on glutamine transport by pulmonary artery endothelial cells.
The Journal of surgical research 1991;50(4):356-61.
1991: Herskowitz K; Bode B P; Block E R; Souba W W
Characterization of L-glutamine transport by pulmonary artery endothelial cells.
The American journal of physiology 1991;260(4 Pt 1):L241-6.
1991: Sekharam K M; Patel J M; Block E R
Plasma membrane-specific phospholipase A1 activation by nitrogen dioxide in pulmonary artery endothelial cells.
Toxicology and applied pharmacology 1991;107(3):545-54.
1991: Block E R
Hydrogen peroxide alters the physical state and function of the plasma membrane of pulmonary artery endothelial cells.
Journal of cellular physiology 1991;146(3):362-9.
1990: Sekharam K M; Patel J M; Block E R
Effect of polyunsaturated fatty acids and phospholipids on [3H]-vitamin E incorporation into pulmonary artery endothelial cell membranes.
Journal of cellular physiology 1990;145(3):555-63.
1990: Hart C M; Tolson J K; Block E R
Fatty acid supplementation protects pulmonary artery endothelial cells from oxidant injury.
American journal of respiratory cell and molecular biology 1990;3(5):479-89.
1990: Bhat G B; Block E R
Hypoxia directly increases serotonin transport by porcine pulmonary artery endothelial cell plasma membrane vesicles.
American journal of respiratory cell and molecular biology 1990;3(4):363-7.
1990: Bhat G B; Patel J M; Block E R
Exposure of pulmonary artery endothelial cells to nitrogen dioxide activates phospholipase A1.
Journal of biochemical toxicology 1990;5(1):67-9.
1990: Patel J M; Sekharam K M; Block E R
Oxidant injury increases cell surface receptor binding of angiotensin II to pulmonary artery endothelial cells.
Journal of biochemical toxicology 1990;5(4):253-8.
1989: Block E R; Patel J M; Edwards D
Mechanism of hypoxic injury to pulmonary artery endothelial cell plasma membranes.
The American journal of physiology 1989;257(2 Pt 1):C223-31.
1989: Patel J M; Yarid F R; Block E R; Raizada M K
Angiotensin receptors in pulmonary arterial and aortic endothelial cells.
The American journal of physiology 1989;256(5 Pt 1):C987-93.
1989: Hart C M; Block E R
Lung serotonin metabolism.
Clinics in chest medicine 1989;10(1):59-70.
1988: Sheridan N P; Block E R
Serotonin transport and fluidity in plasma membrane vesicles: effect of hyperoxia.
The American journal of physiology 1988;254(6 Pt 1):C781-7.
1988: Patel J M; Edwards D A; Block E R; Raizada M K
Effect of nitrogen dioxide on surface membrane fluidity and insulin receptor binding of pulmonary endothelial cells.
Biochemical pharmacology 1988;37(8):1497-507.
1988: Sheridan N P; Block E R
Plasma membrane fluidity measurements in intact endothelial cells: effect of hyperoxia on fluorescence anisotropies of 1-[4-(trimethylamino)phenyl]-6-phenyl hexa-1,3,5-triene.
Journal of cellular physiology 1988;134(1):117-23.
1988: Patel J M; Block E R
The effect of oxidant gases on membrane fluidity and function in pulmonary endothelial cells.
Free radical biology & medicine 1988;4(2):121-34.
1988: Block E R
Interaction between oxygen and cell membranes: modification of membrane lipids to enhance pulmonary artery endothelial cell tolerance to hypoxia.
Experimental lung research 1988;14 Suppl():937-58.
1987: Block E R; Edwards D
Effect of plasma membrane fluidity on serotonin transport by endothelial cells.
The American journal of physiology 1987;253(5 Pt 1):C672-8.
1987: Patel J M; Block E R
Biochemical and metabolic response to nitrogen dioxide-induced endothelial injury.
Research report (Health Effects Institute) 1987;(9):3-20.
1986: Block E R; Patel J M; Angelides K J; Sheridan N P; Garg L C
Hyperoxia reduces plasma membrane fluidity: a mechanism for endothelial cell dysfunction.
Journal of applied physiology (Bethesda, Md. : 1985) 1986;60(3):826-35.
1986: Block E R; Patel J M; Sheridan N P
Endotoxin protects against hyperoxic decrease in membrane fluidity in endothelial cells but not in fibroblasts.
Laboratory investigation; a journal of technical methods and pathology 1986;54(2):146-53.
1985: Block E R; Patel J M; Sheridan N P
Effect of oxygen and endotoxin on lactate dehydrogenase release, 5-hydroxytryptamine uptake, and antioxidant enzyme activities in endothelial cells.
Journal of cellular physiology 1985;122(2):240-8.

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