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Judd Shellito

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Alain J D'Souza; Michelle N Kelly; SanBao Ruan; Xiaowen L Rudner; Shyamal D Desai; Judd E Shellito
Suppression of the macrophage proteasome by ethanol impairs MHC class I antigen processing and presentation.
Michelle N Kelly; Jay K Kolls; Sanbao Ruan; Alain D'Souza; Mingquan Zheng; Judd E Shellito
Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina.
Mingquan Zheng; Rekha R Rapaka; Judd E Shellito; Amy C Yu; Jay K Kolls
Role of interleukin-23-dependent antifungal immune responses in dendritic cell-vaccinated mice.

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2013: Alain J D'Souza; Michelle N Kelly; SanBao Ruan; Xiaowen L Rudner; Shyamal D Desai; Judd E Shellito
Suppression of the macrophage proteasome by ethanol impairs MHC class I antigen processing and presentation.
PloS one 2013;8(2):e56890.
2013: Michelle N Kelly; Jay K Kolls; Sanbao Ruan; Alain D'Souza; Mingquan Zheng; Judd E Shellito
Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(1):285-95.
2011: Mingquan Zheng; Rekha R Rapaka; Judd E Shellito; Amy C Yu; Jay K Kolls
Role of interleukin-23-dependent antifungal immune responses in dendritic cell-vaccinated mice.
Infection and immunity 2011;79(9):3778-83.
2011: Xin Shi; Ping Zhang; Gregory D Sempowski; Judd E Shellito
Thymopoietic and bone marrow response to murine Pneumocystis pneumonia.
Infection and immunity 2011;79(5):2031-42.
2010: Michelle N Kelly; Judd E Shellito
Current understanding of Pneumocystis immunology.
Future microbiology 2010;5(1):43-65.
2009: Xin Shi; Nicole J LeCapitaine; Xiaowen L Rudner; Sanbao Ruan; Judd E Shellito
Lymphocyte apoptosis in murine Pneumocystis pneumonia.
Respiratory research 2009;10():57.
2008: Ping Zhang; Steve Nelson; Gregory J Bagby; robert siggins; Judd E Shellito; David A Welsh
The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice.
Stem cells (Dayton, Ohio) 2008;26(7):1778-86.
2008: Sanbao Ruan; Laura McKinley; Mingquan Zheng; Xiaowen Rudner; Alain D'Souza; Jay K Kolls; Judd E Shellito
Interleukin-12 and host defense against murine Pneumocystis pneumonia.
Infection and immunity 2008;76(5):2130-7.
2007: Kyle I Happel; Xiaowen Rudner; Lee J Quinton; Jennifer L Movassaghi; Charles Clark; Anthony R Odden; Ping Zhang; Gregory J Bagby; Steve Nelson; Judd E Shellito
Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide.
Alcohol (Fayetteville, N.Y.) 2007;41(5):325-33.
2007: Xiaowen L Rudner; Kyle I Happel; Erana A Young; Judd E Shellito
Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection.
Infection and immunity 2007;75(6):3055-61.
2006: Florencia McAllister; Sanbao Ruan; Chad Steele; Mingquan Zheng; Laura McKinley; Lauren Ulrich; Luis Marrero; Judd E Shellito; Jay K Kolls
CXCR3 and IFN protein-10 in Pneumocystis pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1846-54.
2006: Kyle I Happel; Anthony R Odden; Ping Zhang; Judd E Shellito; Gregory J Bagby; Steve Nelson
Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection.
Alcoholism, clinical and experimental research 2006;30(7):1200-7.
2006: Sanbao Ruan; Erana Young; Milson J Luce; Jakob Reiser; Jay K Kolls; Judd E Shellito
Conditional expression of interferon-gamma to enhance host responses to pulmonary bacterial infection.
Pulmonary pharmacology & therapeutics 2006;19(4):251-7.
2005: Mingquan Zheng; Alistair J Ramsay; Myles B Robichaux; Karen A Norris; Corrine Kliment; Christopher Crowe; Rekha R Rapaka; Chad Steele; Florencia McAllister; Judd E Shellito; Luis Marrero; Paul Schwarzenberger; Qiu Zhong; Jay K Kolls
CD4+ T cell-independent DNA vaccination against opportunistic infections.
The Journal of clinical investigation 2005;115(12):3536-44.
2005: Florencia McAllister; Chad Steele; Mingquan Zheng; Judd E Shellito; Jay K Kolls
In vitro effector activity of Pneumocystis murina-specific T-cytotoxic-1 CD8+ T cells: role of granulocyte-macrophage colony-stimulating factor.
Infection and immunity 2005;73(11):7450-7.
2005: Kyle I Happel; Patricia J Dubin; Mingquan Zheng; Nico Ghilardi; Christie Lockhart; Lee J Quinton; Anthony R Odden; Judd E Shellito; Gregory J Bagby; Steve Nelson; Jay K Kolls
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae.
The Journal of experimental medicine 2005;202(6):761-9.
2005: A P Badewa; Lee J Quinton; Judd E Shellito; Carol M Mason
Chemokine receptor 5 and its ligands in the immune response to murine tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2005;85(3):185-95.
2005: Chad Steele; Judd E Shellito; Jay K Kolls
Immunity against the opportunistic fungal pathogen Pneumocystis.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2005;43(1):1-19.
2005: Jill R Schurr; Erana Young; Pat Byrne; Chad Steele; Judd E Shellito; Jay K Kolls
Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria.
Infection and immunity 2005;73(1):532-45.
2004: Judd E Shellito
Failure of host defenses in human immunodeficiency virus.
Seminars in respiratory and critical care medicine 2004;25(1):73-84.
2004: Florencia McAllister; Florencia Mc Allister; Chad Steele; Mingquan Zheng; Erana Young; Judd E Shellito; Luis Marrero; Jay K Kolls
T cytotoxic-1 CD8+ T cells are effector cells against pneumocystis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1132-8.
2003: Chad Steele; Luis Marrero; Steve Swain; Allen G Harmsen; Mingquan Zheng; Gordon D Brown; Siamon Gordon; Judd E Shellito; Jay K Kolls
Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor.
The Journal of experimental medicine 2003;198(11):1677-88.
2003: Kyle I Happel; Mingquan Zheng; Erana Young; Lee J Quinton; Euan Lockhart; Alistair J Ramsay; Judd E Shellito; Jill R Schurr; Gregory J Bagby; Steve Nelson; Jay K Kolls
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4432-6.
2002: Sanbao Ruan; Chandra Tate; Janet J Lee; Thomas Ritter; Jay K Kolls; Judd E Shellito
Local delivery of the viral interleukin-10 gene suppresses tissue inflammation in murine Pneumocystis carinii infection.
Infection and immunity 2002;70(11):6107-13.
2002: Chad Steele; Mingquan Zheng; Erana Young; Luis Marrero; Judd E Shellito; Jay K Kolls
Increased host resistance against Pneumocystis carinii pneumonia in gammadelta T-cell-deficient mice: protective role of gamma interferon and CD8(+) T cells.
Infection and immunity 2002;70(9):5208-15.
2002: Om Prakash; Zhen-Ya Tang; Peng Zhou; Xiaochan Peng; Jay K Kolls; Judd E Shellito; Steve Nelson
Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line.
Alcoholism, clinical and experimental research 2002;26(3):295-302.
2001: Mingquan Zheng; Judd E Shellito; Luis Marrero; Qiu Zhong; S Julian; P Ye; V Wallace; Paul Schwarzenberger; Jay K Kolls
CD4+ T cell-independent vaccination against Pneumocystis carinii in mice.
The Journal of clinical investigation 2001;108(10):1469-74.
2001: P Ye; P B Garvey; Ping Zhang; Steve Nelson; G Bagby; Warren R Summer; Paul Schwarzenberger; Judd E Shellito; Jay K Kolls
Interleukin-17 and lung host defense against Klebsiella pneumoniae infection.
American journal of respiratory cell and molecular biology 2001;25(3):335-40.
2001: P Ye; F H Rodriguez; Suzanne T Kanaly; Kim L Stocking; Jill R Schurr; Paul Schwarzenberger; Peter Oliver; Weitao Huang; P Zhang; J Zhang; Judd E Shellito; Gregory J Bagby; Steve Nelson; Keith Charrier; Jacques J Peschon; Jay K Kolls
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
The Journal of experimental medicine 2001;194(4):519-27.
2001: L Seoane; Judd E Shellito; D Welsh; B P de Boisblanc
Pulmonary hypertension associated with HIV infection.
Southern medical journal 2001;94(6):635-9.
2001: Judd E Shellito; M quan Zheng; P Ye; S Ruan; Mary K Shean; Jay K Kolls
Effect of alcohol consumption on host release of interleukin-17 during pulmonary infection with Klebsiella pneumoniae.
Alcoholism, clinical and experimental research 2001;25(6):872-81.
2001: Om Prakash; V E Rodriguez; Zhen-Ya Tang; Peng Zhou; Roy Coleman; G Dhillon; Judd E Shellito; Steve Nelson
Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 tat-expressing transgenic mice.
Alcoholism, clinical and experimental research 2001;25(3):450-6.
2001: Carol M Mason; Elizabeth Dobard; Judd E Shellito; Steve Nelson
CD4+ lymphocyte responses to pulmonary infection with Mycobacterium tuberculosis in naïve and vaccinated BALB/c mice.
Tuberculosis (Edinburgh, Scotland) 2001;81(5-6):327-34.
2000: Zili Zhang; John Cork; P Ye; D Lei; Paul Schwarzenberger; Warren R Summer; Judd E Shellito; Steve Nelson; Jay K Kolls
Inhibition of TNF-alpha processing and TACE-mediated ectodomain shedding by ethanol.
Journal of leukocyte biology 2000;67(6):856-62.
2000: Judd E Shellito; C Tate; S Ruan; Jay K Kolls
Murine CD4+ T lymphocyte subsets and host defense against Pneumocystis carinii.
The Journal of infectious diseases 2000;181(6):2011-7.
2000: Mary K Shean; Gary B Baskin; D Sullivan; Jill R Schurr; Druie Cavender; Judd E Shellito; Paul Schwarzenberger; Jay K Kolls
Immunomodulation and adenoviral gene transfer to the lungs of nonhuman primates.
Human gene therapy 2000;11(7):1047-55.
2000: Jay Hunt; Everett G Robert; Arthur W Zieske; Abraham P Bautista; M Bukara; D Lei; Judd E Shellito; Steve Nelson; Jay K Kolls; N Skrepnik
Orthotopic human lung carcinoma xenografts in BALB/c mice immunosuppressed with anti-CD4 monoclonal antibodies and chronic alcohol consumption.
Cancer 2000;88(2):468-79.
1999: Jay K Kolls; S Habetz; Mary K Shean; C Vazquez; J A Brown; D Lei; Paul Schwarzenberger; P Ye; S Nelson; Warren R Summer; Judd E Shellito
IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2890-4.
1998: Om Prakash; P Zhang; M Xie; M Ali; Peng Zhou; Roy Coleman; David A Stoltz; Gregory J Bagby; Judd E Shellito; Steve Nelson
The human immunodeficiency virus type I Tat protein potentiates ethanol-induced neutrophil functional impairment in transgenic mice.
Alcoholism, clinical and experimental research 1998;22(9):2043-9.
1998: Om Prakash; B H Joshi; P Zhang; Tak Yee Aw; S Teng; M Ali; Judd E Shellito; Steve Nelson
Transgenic mouse model of ethanol as a cofactor in HIV disease.
Alcoholism, clinical and experimental research 1998;22(5 Suppl):266S-268S.
1998: Judd E Shellito
Alcohol and host defense against pulmonary infection with Pneumocystis carinii.
Alcoholism, clinical and experimental research 1998;22(5 Suppl):208S-211S.
1998: Judd E Shellito; R Olariu
Alcohol decreases T-lymphocyte migration into lung tissue in response to Pneumocystis carinii and depletes T-lymphocyte numbers in the spleens of mice.
Alcoholism, clinical and experimental research 1998;22(3):658-63.
1998: K Omidvari; R Casey; Steve Nelson; R Olariu; Judd E Shellito
Alveolar macrophage release of tumor necrosis factor-alpha in chronic alcoholics without liver disease.
Alcoholism, clinical and experimental research 1998;22(3):567-72.
1998: E Conrad; W Lo; Bennett P deBoisblanc; Judd E Shellito
Reactive airways dysfunction syndrome after exposure to dinitrogen tetroxide.
Southern medical journal 1998;91(4):338-41.
1998: Jay K Kolls; D Lei; David A Stoltz; Ping Zhang; Paul Schwarzenberger; P Ye; G Bagby; Warren R Summer; Judd E Shellito; Steve Nelson
Adenoviral-mediated interferon-gamma gene therapy augments pulmonary host defense of ethanol-treated rats.
Alcoholism, clinical and experimental research 1998;22(1):157-62.
1997: Bennett P deBoisblanc; Carol M Mason; J Andresen; E Logan; M B Bear; S Johnson; Judd E Shellito; Warren R Summer; Steve Nelson
Phase 1 safety trial of Filgrastim (r-metHuG-CSF) in non-neutropenic patients with severe community-acquired pneumonia.
Respiratory medicine 1997;91(7):387-94.
1997: J K Kolls; D Lei; Steve Nelson; Warren R Summer; Judd E Shellito
Pulmonary cytokine gene therapy. Adenoviral-mediated murine interferon gene transfer compartmentally activates alveolar macrophages and enhances bacterial clearance.
Chest 1997;111(6 Suppl):104S.
1997: D Lei; Jack R Lancaster; Mahesh S Joshi; Steve Nelson; David A Stoltz; G J Bagby; G Odom; Judd E Shellito; Jay K Kolls
Activation of alveolar macrophages and lung host defenses using transfer of the interferon-gamma gene.
The American journal of physiology 1997;272(5 Pt 1):L852-9.
1997: Jay K Kolls; D Lei; C Vazquez; G Odom; Warren R Summer; Steve Nelson; Judd E Shellito
Exacerbation of murine Pneumocystis carinii infection by adenoviral-mediated gene transfer of a TNF inhibitor.
American journal of respiratory cell and molecular biology 1997;16(2):112-8.
1996: D Lei; M Lehmann; Judd E Shellito; Steve Nelson; A Siegling; H D Volk; Jay K Kolls
Nondepleting anti-CD4 antibody treatment prolongs lung-directed E1-deleted adenovirus-mediated gene expression in rats.
Human gene therapy 1996;7(18):2273-9.
1996: Jay K Kolls; D Lei; G Odom; Steve Nelson; Warren R Summer; M A Gerber; Judd E Shellito
Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors.
Human gene therapy 1996;7(4):489-97.
1996: Judd E Shellito; Jay K Kolls; R Olariu; James M Beck
Nitric oxide and host defense against Pneumocystis carinii infection in a mouse model.
The Journal of infectious diseases 1996;173(2):432-9.
1995: N B D'Souza; J F Mandujano; S Nelson; W R Summer; Judd E Shellito
Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection.
Alcoholism, clinical and experimental research 1995;19(5):1219-25.
1995: Judd E Shellito; Jay K Kolls; W R Summer
Regulation of nitric oxide release by macrophages after intratracheal lipopolysaccharide.
American journal of respiratory cell and molecular biology 1995;13(1):45-53.
1995: J F Mandujano; N B D'Souza; S Nelson; W R Summer; R C Beckerman; Judd E Shellito
Granulocyte-macrophage colony stimulating factor and Pneumocystis carinii pneumonia in mice.
American journal of respiratory and critical care medicine 1995;151(4):1233-8.
1994: N B D'Souza; F J Mandujano; S Nelson; W R Summer; Judd E Shellito
CD4+ T lymphocyte depletion attenuates lipopolysaccharide-induced tumor necrosis factor secretion by alveolar macrophages in the mouse.
Lymphokine and cytokine research 1994;13(6):359-66.
1993: L Davis; James M Beck; Judd E Shellito
Update: HIV infection and pulmonary host defenses.
Seminars in respiratory infections 1993;8(2):75-85.
1993: Jay K Kolls; James M Beck; S Nelson; W R Summer; Judd E Shellito
Alveolar macrophage release of tumor necrosis factor during murine Pneumocystis carinii pneumonia.
American journal of respiratory cell and molecular biology 1993;8(4):370-6.
1993: James M Beck; M L Warnock; H B Kaltreider; Judd E Shellito
Host defenses against Pneumocystis carinii in mice selectively depleted of CD4+ lymphocytes.
Chest 1993;103(2 Suppl):116S-118S.
1992: Judd E Shellito; S Nelson; R U Sorensen
Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages.
Infection and immunity 1992;60(9):3913-5.
1991: J S Parker; Judd E Shellito; L A Pei; Carol M Mason
Lymphocytic interstitial pneumonitis presenting as recurrent pneumothoraces.
Chest 1991;100(6):1733-5.
1991: James M Beck; H D Liggitt; E N Brunette; H J Fuchs; Judd E Shellito; Robert J Debs
Reduction in intensity of Pneumocystis carinii pneumonia in mice by aerosol administration of gamma interferon.
Infection and immunity 1991;59(11):3859-62.
1991: James M Beck; M L Warnock; Jeffrey L Curtis; M J Sniezek; S M Arraj-Peffer; H B Kaltreider; Judd E Shellito
Inflammatory responses to Pneumocystis carinii in mice selectively depleted of helper T lymphocytes.
American journal of respiratory cell and molecular biology 1991;5(2):186-97.
1991: Steve Nelson; G Bagby; J Andresen; C Nakamura; Judd E Shellito; Warren R Summer
The effects of ethanol, tumor necrosis factor, and granulocyte colony-stimulating factor on lung antibacterial defenses.
Advances in experimental medicine and biology 1991;288():245-53.
1990: E M Imoto; R M Stein; Judd E Shellito; Jeffrey L Curtis
Central airway obstruction due to cytomegalovirus-induced necrotizing tracheitis in a patient with AIDS.
The American review of respiratory disease 1990;142(4):884-6.
1990: James M Beck; V V Suzara; Judd E Shellito
Chronic oral administration of dexamethasone to rats increases cytotoxicity, but not interleukin-1 elaboration, by alveolar macrophages.
Clinical and experimental immunology 1990;82(1):157-62.
1990: Judd E Shellito; V V Suzara; W Blumenfeld; James M Beck; H J Steger; Thomas H Ermak
A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.
The Journal of clinical investigation 1990;85(5):1686-93.
1990: Judd E Shellito; M Sniezek
Altered release of eicosanoids by rat alveolar macrophages during granulomatous pulmonary inflammation.
American journal of respiratory cell and molecular biology 1990;2(3):289-96.
1990: Robert J Debs; H J Fuchs; Ramila Philip; E N Brunette; N Düzgüneş; Judd E Shellito; Denny Liggitt; J R Patton
Immunomodulatory and toxic effects of free and liposome-encapsulated tumor necrosis factor alpha in rats.
Cancer research 1990;50(2):375-80.
1989: H J Fuchs; C W Czarniecki; H H Chiu; M Sniezek; Judd E Shellito
Interferon-gamma increases alveolar macrophage Ia antigen expression despite oral administration of dexamethasone to rats.
American journal of respiratory cell and molecular biology 1989;1(6):525-32.
1989: James M Beck; Judd E Shellito
Effects of human immunodeficiency virus on pulmonary host defenses.
Seminars in respiratory infections 1989;4(2):75-84.
1988: H J Fuchs; J McDowell; Judd E Shellito
Use of allophycocyanin allows quantitative description by flow cytometry of alveolar macrophage surface antigens present in low numbers of cells.
The American review of respiratory disease 1988;138(5):1124-8.
1988: H J Fuchs; M Sniezek; Judd E Shellito
Cellular influx and activation increase macrophage cytotoxicity and interleukin-1 elaboration during pulmonary inflammation in rats.
The American review of respiratory disease 1988;138(3):572-7.
1988: Robert J Debs; H J Fuchs; Ramila Philip; A B Montgomery; E N Brunette; Denny Liggitt; J S Patton; Judd E Shellito
Lung-specific delivery of cytokines induces sustained pulmonary and systemic immunomodulation in rats.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3482-8.
1987: Judd E Shellito; M Sniezek; M Warnock
Acquisition of peroxidase activity by rat alveolar macrophages during pulmonary inflammation.
The American journal of pathology 1987;129(3):567-77.
1987: M L Warnock; M Sniezek; Judd E Shellito
Endogenous peroxidase activity as a marker of macrophage renewal during BCG-induced inflammation in the rat lung.
The American journal of pathology 1987;128(1):171-80.
1986: Robert G Sitrin; P G Brubaker; Judd E Shellito; H B Kaltreider
The distribution of procoagulant and plasminogen activator activities among density fractions of normal rabbit alveolar macrophages.
The American review of respiratory disease 1986;133(3):468-72.
1985: Judd E Shellito; H B Kaltreider
Heterogeneity of immunologic function among subfractions of normal rat alveolar macrophages. II. Activation as a determinant of functional activity.
The American review of respiratory disease 1985;131(5):678-83.
1984: Judd E Shellito; H B Kaltreider
Heterogeneity of immunologic function among subfractions of normal rat alveolar macrophages.
The American review of respiratory disease 1984;129(5):747-53.