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Xiu-Da Shen
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51
Busuttil, Ronald
49
Kupiec-Weglinski, Jerzy
34
Gao, Feng
25
Ke, Bibo
14
Lassman, Charles
14
Coito, Ana
14
Amersi, Farin
13
Zhai, Yuan
10
Volk, Hans-Dieter
10
Anselmo, Dean
10
Farmer, Douglas
9
Ghobrial, Mark
7
Fondevila, Constantino
7
Tsuchihashi, Sei-ichiro
7
Melinek, Judy
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All Publications
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2009: Fondevila C; Shen X-D; Duarte S; Busuttil R W; Coito A J
Cytoprotective effects of a cyclic RGD peptide in steatotic liver cold ischemia and reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(10):2240-50.
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2009: Ke Bibo; Shen Xiu-Da; Gao Feng; Qiao Bo; Ji Haofeng; Busuttil Ronald W; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Small interfering RNA targeting heme oxygenase-1 (HO-1) reinforces liver apoptosis induced by ischemia-reperfusion injury in mice: HO-1 is necessary for cytoprotection.
Human gene therapy 2009;20(10):1133-42.
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2009: Liu Dahai; Shen Xiu-Da; Zhai Yuan; Lam Wengsi; Liao Jingying; Busuttil Ronald W; Ghobrial Rafik M
Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients.
PloS one 2009;4(6):e6076.
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2008: Farmer Douglas G; Kaldas Fady; Anselmo Dean; Katori Masamichi; Shen Xiu-Da; Lassman Charles; Kaldas Marian; Clozel Martine; Busuttil Ronald W; Kupiec-Weglinski Jerzy
Tezosentan, a novel endothelin receptor antagonist, markedly reduces rat hepatic ischemia and reperfusion injury in three different models.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(12):1737-44.
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2008: Fondevila Constantino; Shen Xiu-Da; Tsuchihashi Seiichiro; Uchida Yoichiro; Freitas Maria Cecilia; Ke Bibo; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The membrane attack complex (C5b-9) in liver cold ischemia and reperfusion injury.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(8):1133-41.
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2008: Zhai Yuan; Qiao Bo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Cheng Genhong; Platt Jeffrey L; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Evidence for the pivotal role of endogenous toll-like receptor 4 ligands in liver ischemia and reperfusion injury.
Transplantation 2008;85(7):1016-22.
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2008: Jindra Peter T; Hsueh Aileen; Hong Longshen; Gjertson David; Shen Xiu-Da; Gao Feng; Dang Julie; Mischel Paul S; Baldwin William M; Fishbein Michael C; Kupiec-Weglinski Jerzy W; Reed Elaine F
Anti-MHC class I antibody activation of proliferation and survival signaling in murine cardiac allografts.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2214-24.
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2008: Zhai Yuan; Shen Xiu-Da; Gao Feng; Zhao Alice; Freitas Maria Cecilia; Lassman Charles; Luster Andrew D; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CXCL10 regulates liver innate immune response against ischemia and reperfusion injury.
Hepatology (Baltimore, Md.) 2008;47(1):207-14.
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2007: Shen X-D; Ke B; Zhai Y; Tsuchihashi S-I; Gao F; Duarte S; Coito A; Busuttil R W; Allison A C; Kupiec-Weglinski J W
Diannexin, a novel annexin V homodimer, protects rat liver transplants against cold ischemia-reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(11):2463-71.
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2007: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Tsuchihashi Sei-Ichiro; Lassman Charles R; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation model.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(10):1435-43.
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2007: Semiletova Natalya V; Shen Xiu-Da; Feldman Daniel M; Gao Feng; Mhoyan Ana; Liu Dhai; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains.
Cellular immunology 2007;248(1):48-58.
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2007: Ke Bibo; Shen Xiu-Da; Tsuchihashi Sei-Ichiro; Gao Feng; Araujo Jesus A; Busuttil Ronald W; Ritter Thomas; Kupiec-Weglinski Jerzy W
Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity.
Human gene therapy 2007;18(4):355-66.
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2007: Hoglen Niel C; Anselmo Dean M; Katori Masamichi; Kaldas Marian; Shen Xiu-Da; Valentino Karen L; Lassman Charles; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Farmer Douglas G
A caspase inhibitor, IDN-6556, ameliorates early hepatic injury in an ex vivo rat model of warm and cold ischemia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(3):361-6.
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2007: Moore Carolina; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Coito Ana J
Fibronectin-alpha4beta1 integrin interactions regulate metalloproteinase-9 expression in steatotic liver ischemia and reperfusion injury.
The American journal of pathology 2007;170(2):567-77.
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2006: Zhai Yuan; Shen Xiu-da; Hancock Wayne W; Gao Feng; Qiao Bo; Lassman Charles; Belperio John A; Strieter Robert M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CXCR3+CD4+ T cells mediate innate immune function in the pathophysiology of liver ischemia/reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6313-22.
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2006: Tsuchihashi Sei-ichiro; Fondevila Constantino; Shaw Gray D; Lorenz Meike; Marquette Kimberly; Benard Susan; Shen Xiu-Da; Ke Bibo; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Molecular characterization of rat leukocyte P-selectin glycoprotein ligand-1 and effect of its blockade: protection from ischemia-reperfusion injury in liver transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):616-24.
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2005: Semiletova Natalya V; Shen Xiu-Da; Baibakov Boris; Feldman Daniel M; Mukherjee Kaushik; Frank Jonathan M; Stepkowski Stainslaw M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Inhibition of chronic rejection by antibody induced vascular accommodation in fully allogeneic heart allografts.
Transplantation 2005;80(11):1535-40.
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2005: Shen Xiu-Da; Gao Feng; Ke Bibo; Zhai Yuan; Lassman Charles R; Tsuchihashi Sei-Ichiro; Farmer Douglas G; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Inflammatory responses in a new mouse model of prolonged hepatic cold ischemia followed by arterialized orthotopic liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(10):1273-81.
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2005: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Busuttil Ronald W; Cheng Genhong; Kupiec-Weglinski Jerzy W
Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(8):1793-800.
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2005: Liu D; Shen X-D; Fang Z; Gao F; Semiletova N; Cao M-J; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Identification of early tolerance regulator genes induced by allochimeric therapy using microarray-based genomewide scan.
Transplantation proceedings 2005;37(4):1942-3.
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2005: Semiletova N V; Shen X-D; Feldman D M; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Donor MHC class I peptides in conjunction with self-epitopes induce donor-specific tolerance in a dose-dependent manner but unable to abrogate chronic rejection.
Transplantation proceedings 2005;37(4):1937-9.
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2005: Moore C; Shen X D; Fondevila C; Gao F; Coito A J
Blockade of fibronectin-alpha4beta1 adhesive interactions down-regulates cyclooxygenase-2 inducible nitric oxide synthase and prolongs recipient survival in a 24-hour model of cold hepatic ischemia-reperfusion injury.
Transplantation proceedings 2005;37(4):1682-3.
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2005: Fondevila C; Shen X D; Moore C; Busuttil R W; Coito A J
Cyclic RGD peptides with high affinity for alpha5beta1 integrin protect genetically fat Zucker rat livers from cold ischemia/reperfusion injury.
Transplantation proceedings 2005;37(4):1679-81.
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2005: Ke Bibo; Shen Xiu-Da; Gao Feng; Tsuchihashi Seiichiro; Farmer Douglas G; Briscoe David; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
The CD154-CD40 T-cell co-stimulation pathway in liver ischemia and reperfusion inflammatory responses.
Transplantation 2005;79(9):1078-83.
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2005: Moore C; Shen X D; Fondevila C; Coito A J
Fibronectin-alpha4beta1 integrin interactions modulate p42/44 MAPK phosphorylation in steatotic liver cold ischemia-reperfusion injury.
Transplantation proceedings 2005;37(1):432-4.
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2005: Semiletova N V; Shen X D; Slomowitz S J; Baibakov B; Feldman D M; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Allochimeric therapy induces unique regulatory T cells that mitigate chronic rejection.
Transplantation proceedings 2005;37(1):35-6.
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2005: Farmer Douglas G; Shen Xiu-Da; Amersi Farin; Anselmo Dean; Ma Jeffrey P; Ke Bibo; Gao Feng; Dry Sarah; Fernandez Susan; Shaw Gray D; McDiarmid Sue V; Busuttil Ronald W; Kupiec-Weglinski Jerzy
CD62 blockade with P-Selectin glycoprotein ligand-immunoglobulin fusion protein reduces ischemia-reperfusion injury after rat intestinal transplantation.
Transplantation 2005;79(1):44-51.
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2004: Zhai Yuan; Shen Xiu-da; O'Connell Ryan; Gao Feng; Lassman Charles; Busuttil Ronald W; Cheng Genhong; Kupiec-Weglinski Jerzy W
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7115-9.
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2004: Fondevila Constantino; Shen Xiu-Da; Tsuchiyashi Seiichiro; Yamashita Kenichiro; Csizmadia Eva; Lassman Charles; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Bach Fritz H
Biliverdin therapy protects rat livers from ischemia and reperfusion injury.
Hepatology (Baltimore, Md.) 2004;40(6):1333-41.
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2004: Ke Bibo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Interleukin 13 gene transfer in liver ischemia and reperfusion injury: role of Stat6 and TLR4 pathways in cytoprotection.
Human gene therapy 2004;15(7):691-8.
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2004: Carmody I C; Meng L; Shen X D; Anselmo D; Gao F; Ke B; Ma J P; Kupiec-Weglinski J W; McDiarmid S V; Busuttil R W; Shaw G; Farmer D G
P-selectin knockout mice have improved outcomes with both warm ischemia and small bowel transplantation.
Transplantation proceedings 2004;36(2):263-4.
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2004: Ke Bibo; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Löwenstein Pedro R; Castro Maria G; Kupiec-Weglinski Jerzy W
Gene therapy for liver transplantation using adenoviral vectors: CD40-CD154 blockade by gene transfer of CD40Ig protects rat livers from cold ischemia and reperfusion injury.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(1):38-45.
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2003: Ke Bibo; Shen Xiu-Da; Lassman Charles R; Gao Feng; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/reperfusion injury are heme oxygenase-1 dependent.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(9):1076-82.
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2003: Ke Bibo; Shen Xiu-Da; Lassman Charles R; Gao Feng; Katori Masamichi; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Interleukin-13 gene transfer protects rat livers from antigen-independent injury induced by ischemia and reperfusion.
Transplantation 2003;75(8):1118-23.
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2003: Amersi Farin; Shen Xiu-Da; Moore Carolina; Melinek Judy; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Coito Ana J
Fibronectin-alpha 4 beta 1 integrin-mediated blockade protects genetically fat Zucker rat livers from ischemia/reperfusion injury.
The American journal of pathology 2003;162(4):1229-39.
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2003: Semiltova Natalya; Shen Xiu-Da; Fishbein Michael C; Gao Feng; Slomowitz Samuel J; Jiao Qingsheng; Mukherjee Kaushik; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Posttransplant administration of allochimeric major histocompatibility complex class-I-molecules induces true transplantation tolerance.
Transplantation 2003;75(4):550-3.
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2003: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Gao Feng; Anselmo Dean; Lassman Charles R; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection.
Hepatology (Baltimore, Md.) 2003;37(2):296-303.
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2002: Ke Bibo; Shen Xiu-Da; Zhai Yuan; Gao Feng; Busuttil Ronald W; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro.
Human gene therapy 2002;13(15):1845-57.
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2002: Anselmo Dean M; Amersi Farin F; Shen Xiu-Da; Gao Feng; Katori Masamichi; Lassman Charles; Ke Bibo; Coito Ana J; Ma Jeffrey; Brinkmann Volker; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Farmer Douglas G
FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(9):843-9.
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2002: Sawitzki Birgit; Amersi Farin; Ritter Thomas; Fisser Marion; Shen Xiu-Da; Ke Bibo; Busuttil Ronald; Volk Hans-Dieter; Kupiec-Weglinski Jerzy W
Upregulation of Bag-1 by ex vivo gene transfer protects rat livers from ischemia/reperfusion injury.
Human gene therapy 2002;13(12):1495-504.
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2002: Shen Xiu-Da; Ke Bibo; Zhai Yuan; Amersi Farin; Gao Feng; Anselmo Dean M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection.
Transplantation 2002;74(3):315-9.
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2002: Anselmo D; Amersi F F; Shen X-D; Gao F; Katori M; Ke B; Lassman C; Coito A J; Brinkmann V; Busuttil R W; Kupiec-Weglinski J W; Farmer D G
FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injury.
Transplantation proceedings 2002;34(5):1467-8.
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2002: Ke B; Shen X-D; Buelow R; Melinek J; Amersi F; Gao F; Ritter T; Volk H D; Busuttil R W; Kupiec-Weglinski J W
Heme oxygenase-1 gene transfer prevents CD95/FasL-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.
Transplantation proceedings 2002;34(5):1465-6.
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2002: Semiletova N; Shen X D; Gao F; Slomowitz S J; Jiao Q; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Regulatory T cells induced by allochimeric major histocompatability class I therapy inhibit allograft apoptosis.
Transplantation proceedings 2002;34(5):1402.
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2002: Zhai Yuan; Shen Xiu-Da; Gao Feng; Coito Ana J; Wasowska Barbara A; Salama Alan; Schmitt Isabela; Busuttil Ronald W; Sayegh Mohamed H; Kupiec-Weglinski Jerzy W
The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1270-6.
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2002: Coito Ana J; Buelow Roland; Shen Xiu-Da; Amersi Farin; Moore Carolina; Volk Hans-Dieter; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury.
Transplantation 2002;74(1):96-102.
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2002: Ke Bibo; Buelow Roland; Shen Xiu-Da; Melinek Judy; Amersi Farin; Gao Feng; Ritter Thomas; Volk Hans-Dieter; Busuttil Ronald W; Kupiec-Weglinski Jerzy W
Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.
Human gene therapy 2002;13(10):1189-99.
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2002: Amersi Farin; Nelson Sally K; Shen Xiu Da; Kato Hirohisa; Melinek Judy; Kupiec-Weglinski Jerzy W; Horwitz Lawrence D; Busuttil Ronald W; Horwitz Marcus A
Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8915-20.
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2002: Farmer D G; Amersi F; Shen X D; Gao F; Anselmo D; Ma J; Dry S; McDiarmid S V; Shaw G; Busuttil R W; Kupiec-Weglinski J
Improved survival through the reduction of ischemia-reperfusion injury after rat intestinal transplantation using selective P-selectin blockade with P-selectin glycoprotein ligand-Ig.
Transplantation proceedings 2002;34(3):985.
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2002: Hancock Wayne W; Gao Wei; Shemmeri Nida; Shen Xiu-Da; Gao Feng; Busuttil Ronald W; Zhai Yuan; Kupiec-Weglinski Jerzy W
Immunopathogenesis of accelerated allograft rejection in sensitized recipients: humoral and nonhumoral mechanisms.
Transplantation 2002;73(9):1392-7.
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2002: Amersi Farin; Shen Xiu-Da; Anselmo Dean; Melinek Judy; Iyer Suhasani; Southard Daniel J; Katori Masamichi; Volk Hans-Dieter; Busuttil Ronald W; Buelow Roland; Kupiec-Weglinski Jerzy W
Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway.
Hepatology (Baltimore, Md.) 2002;35(4):815-23.
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2001: Zhai Y; Shen X D; Lehmann M; Busuttil R; Volk H D; Kupiec-Weglinski J W
T cell subsets and in vitro immune regulation in "infectious" transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):4814-20.
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2001: Singer J S; Mhoyan A; Fishbein M C; Shen X D; Gao F; Zhao D; Coito A J; Reemtsen B L; Amersi F; Busuttil R W; Kupiec-Weglinski J W; Ghobrial R M
Allochimeric class I MHC molecules prevent chronic rejection and attenuate alloantibody responses.
Transplantation 2001;72(8):1408-16.
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2001: Ke B; Shen X D; Melinek J; Gao F; Ritter T; Volk H D; Busuttil R W; Kupiec-Weglinski J W
Heme oxygenase-1 gene therapy: a novel immunomodulatory approach in liver allograft recipients?
Transplantation proceedings 2001;33(1-2):581-2.
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2001: Kupiec-Weglinski J W; Shen X D; Gao F; Zhai Y; Coito A J; Sayegh M H
CD40 ligand-CD40 T cell costimulation pathway is required for host sensitization in the immune cascade leading to accelerated allograft rejection.
Transplantation proceedings 2001;33(1-2):304-5.
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1999: Amersi F; Buelow R; Kato H; Ke B; Coito A J; Shen X D; Zhao D; Zaky J; Melinek J; Lassman C R; Kolls J K; Alam J; Ritter T; Volk H D; Farmer D G; Ghobrial R M; Busuttil R W; Kupiec-Weglinski J W
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury.
The Journal of clinical investigation 1999;104(11):1631-9.
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