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Zhu-Fang Shen

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Guo-Jiang Hou; Shao-Cong Hou; Yi Huan; Cai-Na Li; Lin-Yi Li; Quan Liu; Shuai-Nan Liu; Su-Juan Sun; Zhu-Fang Shen
Long-term treatment with EXf, a peptide analog of Exendin-4, improves β-cell function and survival in diabetic KKAy mice.
Dong-Mei Wang; Jin-Zhao Wei; Bao-Yan Fan; Quan Liu; Zhu-Fang Shen; Hai-Bo Zhu; Song Wu
[Synthesis and biological evaluation of tetrahydrocoptisine quaternary ammonium compounds].
Ning Shen; Yi Huan; Zhu-Fang Shen
Berberine inhibits mouse insulin gene promoter through activation of AMP activated protein kinase and may exert beneficial effect on pancreatic β-cell.

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2013: Guo-Jiang Hou; Shao-Cong Hou; Yi Huan; Cai-Na Li; Lin-Yi Li; Quan Liu; Shuai-Nan Liu; Su-Juan Sun; Zhu-Fang Shen
Long-term treatment with EXf, a peptide analog of Exendin-4, improves β-cell function and survival in diabetic KKAy mice.
Peptides 2013;40():123-32.
2012: Dong-Mei Wang; Jin-Zhao Wei; Bao-Yan Fan; Quan Liu; Zhu-Fang Shen; Hai-Bo Zhu; Song Wu
[Synthesis and biological evaluation of tetrahydrocoptisine quaternary ammonium compounds].
Yao xue xue bao = Acta pharmaceutica Sinica 2012;47(12):1640-5.
2012: Ning Shen; Yi Huan; Zhu-Fang Shen
Berberine inhibits mouse insulin gene promoter through activation of AMP activated protein kinase and may exert beneficial effect on pancreatic β-cell.
European journal of pharmacology 2012;694(1-3):120-6.
2012: B K He; B C B Ko; P P Li; Z B Li; X P Lu; Z Q Ning; D S Pan; S Shan; Zhu-Fang Shen; B L Zhang; G F Dou; Y Gao
In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist.
PPAR research 2012;2012():546548.
2011: Hui-Zheng Fu; Chuang-Jun Li; Jing-Zhi Yang; Zhu-Fang Shen; Dong-Ming Zhang
Potential anti-inflammatory constituents of the stems of Gordonia chrysandra.
Journal of natural products 2011;74(5):1066-72.
2011: Quan Liu; Shuai-nan Liu; Zhi-yu Chen; Lei Lei; Lin-yi Li; Ning Zhang; Zhu-Fang Shen
[A dyslipidemia animal model induced by poloxamer 407 in golden hamsters and pilot study on the mechanism].
Yao xue xue bao = Acta pharmaceutica Sinica 2011;46(4):406-11.
2011: Gang Ni; Zhu-Fang Shen; Yang Lu; Ying-Hong Wang; Yan-Bo Tang; Ruo-yun Chen; Zhi-You Hao; De-Quan Yu
Glucokinase-activating sesquinlignans from the rhizomes of Acorus tatarinowii Schott.
The Journal of organic chemistry 2011;76(7):2056-61.
2011: Ran Yu; Yan-Li Zhou; Yi Huan; Quan Liu; Zhu-Fang Shen; Zhan-Zhu Liu
[Design, synthesis, and PPARalpha/gamma agonistic activity of novel tetrahydroisoquinoline derivatives].
Yao xue xue bao = Acta pharmaceutica Sinica 2011;46(3):311-6.
2011: Shuai-nan Liu; Yi Huan; Lin-yi Li; Quan Liu; Su-juan Sun; Zhu-Fang Shen
Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: is that a latent disadvantage?
Journal of translational medicine 2011;9():176.
2010: Bei Han; Yi Huan; Zi-Yun Lin; Peng Li; Zhu-Fang Shen; Da-Li Yin; Hai-Hong Huang
[Design, synthesis and in vitro activity of glycinamide-bearing compounds as DPP-IV inhibitors].
Yao xue xue bao = Acta pharmaceutica Sinica 2010;45(11):1379-84.
2010: Ning Shen; Cai-Na Li; Yi Huan; Zhu-Fang Shen
[Advances of the mechanism study on berberine in the control of blood glucose and lipid as well as metabolism disorders].
Yao xue xue bao = Acta pharmaceutica Sinica 2010;45(6):699-704.
2010: Guang-ming Song; Yi Huan; Su-juan Sun; Yue-teng Chen; Quan Liu; Zhu-Fang Shen
Biological activity of EXf, a peptide analogue of exendin-4.
European journal of pharmacology 2010;628(1-3):261-7.
2010: Ning Zhang; Yi Huan; Hui Huang; Guang-ming Song; Su-juan Sun; Zhu-Fang Shen
Atorvastatin improves insulin sensitivity in mice with obesity induced by monosodium glutamate.
Acta pharmacologica Sinica 2010;31(1):35-42.
2009: Li-Xia Ji; Ning Shen; Cai-Na Li; Quan Liu; Yi Huan; Zhu-Fang Shen
[Inhibition effect of epalrestat on rat lens osmotic expansion].
Yao xue xue bao = Acta pharmaceutica Sinica 2009;44(10):1107-11.
2009: Chen-Xi Hu; Hui Huang; Li Zhang; You Huang; Zhu-Fang Shen; Ke-di Cheng; Guan-Hua Du; Ping Zhu
A new screening method based on yeast-expressed human dipeptidyl peptidase IV and discovery of novel inhibitors.
Biotechnology letters 2009;31(7):979-84.
2009: Yi Huan; Zhu-Fang Shen
[A novel cell model targeted on GLP-1 receptor for application to anti-diabetic candidates screening].
Yao xue xue bao = Acta pharmaceutica Sinica 2009;44(3):309-13.
2008: Shuai-Nan Liu; Quan Liu; Zhu-Fang Shen
[A preliminary study on the mechanism of impaired beta cell function in monosodium glutamate obese rat with insulin resistance].
Yao xue xue bao = Acta pharmaceutica Sinica 2008;43(11):1106-11.
2008: Zhen-ji Wang; Quan Liu; Ping-Ping Li; Chen-hui Zou; Zhu-Fang Shen
Effect of GCP-02, a PPARalpha/gamma dual activator, on glucose and lipid metabolism in insulin-resistant mice.
European journal of pharmacology 2008;580(1-2):277-83.
2008: Lu Tie; Ying Xu; Yan-Hua Lin; Xiao-Hao Yao; Hong-Li Wu; Yu-Hua Li; Zhu-Fang Shen; He-Ming Yu; Xue-Jun Li
Down-regulation of brain-pancreas relative protein in diabetic rats and by high glucose in PC12 cells: prevention by calpain inhibitors.
Journal of pharmacological sciences 2008;106(1):28-37.
2007: Shuai-nan Liu; Zhu-Fang Shen
[A new target for diabetes therapy: advances in the research of glycogen synthase kinase-3 inhibitors].
Yao xue xue bao = Acta pharmaceutica Sinica 2007;42(12):1227-31.
2006: Ping-Ping Li; Song Shan; Yue-teng Chen; Zhi-Qiang Ning; Su-juan Sun; Quan Liu; Xian-Ping Lu; Ming-zhi Xie; Zhu-Fang Shen
The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats.
British journal of pharmacology 2006;148(5):610-8.
2006: Zhe-Feng Cai; Quan Liu; Ping-Ping Li; Zong-ru Guo; Zhu-Fang Shen
Synthesis and anti-diabetic activity of (RS)-2-ethoxy-3-{4-[2-(4-trifluoro-methanesulfonyloxy-phenyl)-ethoxy]-phenyl}-propionic acid.
Acta pharmacologica Sinica 2006;27(5):597-602.
2006: Tuo Deng; Song Shan; Ping-Ping Li; Zhu-Fang Shen; Xian-Ping Lu; Jing Cheng; Zhi-Qiang Ning
Peroxisome proliferator-activated receptor-gamma transcriptionally up-regulates hormone-sensitive lipase via the involvement of specificity protein-1.
Endocrinology 2006;147(2):875-84.
2005: Shi-ying Ding; Zhu-Fang Shen; Yue-teng Chen; Su-juan Sun; Quan Liu; Ming-zhi Xie
Pioglitazone can ameliorate insulin resistance in low-dose streptozotocin and high sucrose-fat diet induced obese rats.
Acta pharmacologica Sinica 2005;26(5):575-80.
2004: Shi-ying Ding; Zhu-Fang Shen; Yue-teng Chen; Ming-zhi Xie
[Ameliorations of pioglitazone on insulin resistance in spontaneous IGT-OLETF rats].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(7):514-7.
2003: Su-juan Sun; Zhu-Fang Shen; Yue-teng Chen; Ling Tang; Shi-ying Ding; Ming-zhi Xie
[Effects of conjugated linoleic acid on obese MSG mice with insulin resistance].
Yao xue xue bao = Acta pharmaceutica Sinica 2003;38(12):904-7.
2002: Fei Ye; Zhu-Fang Shen; Feng-xia Qiao; Dan-yang Zhao; Ming-zhi Xie
Experimental treatment of complications in alloxan diabetic rats with alpha-glucosidase inhibitor from the Chinese medicinal herb ramulus mori.
Yao xue xue bao = Acta pharmaceutica Sinica 2002;37(2):108-12.