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Thomas Shenk

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Christine M O'Connor; Thomas Shenk
Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts.
Sarah L Grady; Jesse Hwang; Joshua D Rabinowitz; Livia Vastag; Thomas Shenk
Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase.
Nicole Gudleski-O'Regan; Ileana M Cristea; Todd M Greco; Thomas Shenk
Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity.

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All Publications

2012: Christine M O'Connor; Thomas Shenk
Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts.
Journal of virology 2012;86(21):11425-33.
2012: Sarah L Grady; Jesse Hwang; Joshua D Rabinowitz; Livia Vastag; Thomas Shenk
Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase.
Journal of virology 2012;86(15):8259-68.
2012: Nicole Gudleski-O'Regan; Ileana M Cristea; Todd M Greco; Thomas Shenk
Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity.
Cell host & microbe 2012;12(1):86-96.
2012: Laura J Terry; Livia Vastag; Joshua D Rabinowitz; Thomas Shenk
Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):3071-6.
2011: Sean T H Liu; Stephen B Milne; David S Myers; Joshua D Rabinowitz; Ronit Sharon-Friling; H Alex Brown; Pavlina T Ivanova; Thomas Shenk
Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(31):12869-74.
2011: Christine M O'Connor; Thomas Shenk
Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread.
Journal of virology 2011;85(8):3700-7.
2010: Ileana M Cristea; Nathaniel J. Moorman; Scott S Terhune; Christian D Cuevas; Erin S O'Keefe; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.
Journal of virology 2010;84(15):7803-14.
2010: Nathaniel J Moorman; Ronit Sharon-Friling; Thomas Shenk; Ileana M Cristea
A targeted spatial-temporal proteomics approach implicates multiple cellular trafficking pathways in human cytomegalovirus virion maturation.
Molecular & cellular proteomics : MCP 2010;9(5):851-60.
2010: Andrew Womack; Thomas Shenk
Human cytomegalovirus tegument protein pUL71 is required for efficient virion egress.
mBio 2010;1(5):.
2010: Scott S Terhune; Nathaniel J. Moorman; Ileana M Cristea; John Paul Savaryn; Christian Cuevas-Bennett; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.
PLoS pathogens 2010;6(6):e1000965.
2009: Dora P Mitchell; John P Savaryn; Nathaniel J. Moorman; Thomas Shenk; Scott S Terhune
Human cytomegalovirus UL28 and UL29 open reading frames encode a spliced mRNA and stimulate accumulation of immediate-early RNAs.
Journal of virology 2009;83(19):10187-97.
2008: Anders E Lilja; Thomas Shenk
Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(50):19950-5.
2008: Jörg Schröer; Thomas Shenk
Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19468-73.
2008: Joshua C. Munger; Bryson D Bennett; Anuraag Parikh; Xiao-Jiang Feng; Jessica McArdle; Herschel Rabitz; Thomas Shenk; Joshua D Rabinowitz
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy.
Nature biotechnology 2008;26(10):1179-86.
2008: Christian Cuevas-Bennett; Thomas Shenk
Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts.
Journal of virology 2008;82(19):9525-36.
2008: Nathaniel J. Moorman; Ileana M Cristea; Scott S Terhune; Michael P Rout; Brian T Chait; Thomas Shenk
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex.
Cell host & microbe 2008;3(4):253-62.
2008: Eain Murphy; Jirí Vanícek; Harlan Robins; Thomas Shenk; Arnold J Levine
Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5453-8.
2008: Anders E Lilja; W L William Chang; Peter A Barry; S Patricia Becerra; Thomas Shenk
Functional genetic analysis of rhesus cytomegalovirus: Rh01 is an epithelial cell tropism factor.
Journal of virology 2008;82(5):2170-81.
2008: Eain Murphy; Thomas Shenk
Human cytomegalovirus genome.
Current topics in microbiology and immunology 2008;325():1-19.
2008: Thomas Shenk; Mark F Stinski
Human cytomegalovirus. Preface.
Current topics in microbiology and immunology 2008;325():v.
2007: Dai Wang; Qian-Chun Yu; Jörg Schröer; Eain Murphy; Thomas Shenk
Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):20037-42.
2007: Felicia Goodrum; Matthew Reeves; John Sinclair; Kevin High; Thomas Shenk
Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro.
Blood 2007;110(3):937-45.
2007: Scott S Terhune; Emi Torigoi; Nathaniel J. Moorman; Maria Silva; Zhikang Qian; Thomas Shenk; Dong Yu
Human cytomegalovirus UL38 protein blocks apoptosis.
Journal of virology 2007;81(7):3109-23.
2007: Leor S Weinberger; Thomas Shenk
An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer.
PLoS biology 2007;5(1):e9.
2006: Ronit Sharon-Friling; Joseph Goodhouse; Anamaris M Colberg-Poley; Thomas Shenk
Human cytomegalovirus pUL37x1 induces the release of endoplasmic reticulum calcium stores.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19117-22.
2006: Joshua C. Munger; Sunil Bajad; Hilary A Coller; Thomas Shenk; Joshua D Rabinowitz
Dynamics of the cellular metabolome during human cytomegalovirus infection.
PLoS pathogens 2006;2(12):e132.
2006: Caroline A Kulesza; Thomas Shenk
Murine cytomegalovirus encodes a stable intron that facilitates persistent replication in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18302-7.
2006: Xuyan Feng; Jörg Schröer; Dong Yu; Thomas Shenk
Human cytomegalovirus pUS24 is a virion protein that functions very early in the replication cycle.
Journal of virology 2006;80(17):8371-8.
2006: Joshua C. Munger; Dong Yu; Thomas Shenk
UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells.
Journal of virology 2006;80(7):3541-8.
2006: Miguel Gaspar; Thomas Shenk
Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2821-6.
2005: Dai Wang; Thomas Shenk
Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18153-8.
2005: Dai Wang; Thomas Shenk
Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism.
Journal of virology 2005;79(16):10330-8.
2005: Maria C Silva; Jörg Schröer; Thomas Shenk
Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2081-6.
2004: Michael Nevels; Christina Paulus; Thomas Shenk
Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17234-9.
2004: Caroline A Kulesza; Thomas Shenk
Human cytomegalovirus 5-kilobase immediate-early RNA is a stable intron.
Journal of virology 2004;78(23):13182-9.
2004: Dai Wang; Wade A Bresnahan; Thomas Shenk
Human cytomegalovirus encodes a highly specific RANTES decoy receptor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16642-7.
2004: Susan M Varnum; Daniel N Streblow; Matthew Monroe; Patricia Smith; Kenneth J Auberry; Ljiljana Pasa-Tolic; Dai Wang; David G Camp; Karin Rodland; Steven Wiley; William J Britt; Thomas Shenk; Richard D Smith; Jay A Nelson
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome.
Journal of virology 2004;78(20):10960-6.
2004: Scott S Terhune; Jörg Schröer; Thomas Shenk
RNAs are packaged into human cytomegalovirus virions in proportion to their intracellular concentration.
Journal of virology 2004;78(19):10390-8.
2004: Joan E Adamo; Jörg Schröer; Thomas Shenk
Human cytomegalovirus TRS1 protein is required for efficient assembly of DNA-containing capsids.
Journal of virology 2004;78(19):10221-9.
2004: Felicia Goodrum; Craig T Jordan; Scott S Terhune; Kevin High; Thomas Shenk
Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations.
Blood 2004;104(3):687-95.
2004: Michael Nevels; Wolfram Brune; Thomas Shenk
SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication.
Journal of virology 2004;78(14):7803-12.
2004: Jean F Challacombe; Andreas Rechtsteiner; Raphael Gottardo; Luis M Rocha; Edward P Browne; Thomas Shenk; Michael R Altherr; Thomas S Brettin
Evaluation of the host transcriptional response to human cytomegalovirus infection.
Physiological genomics 2004;18(1):51-62.
2003: Eain Murphy; Dong Yu; Jane Grimwood; Jeremy Schmutz; Mark Dickson; Michael A Jarvis; Gabriele Hahn; Jay A Nelson; Richard Myers; Thomas Shenk
Coding potential of laboratory and clinical strains of human cytomegalovirus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14976-81.
2003: Eain Murphy; Isidore Rigoutsos; Tetsuo Shibuya; Thomas Shenk
Reevaluation of human cytomegalovirus coding potential.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13585-90.
2003: Wolfram Brune; Michael Nevels; Thomas Shenk
Murine cytomegalovirus m41 open reading frame encodes a Golgi-localized antiapoptotic protein.
Journal of virology 2003;77(21):11633-43.
2003: Dong Yu; Maria C Silva; Thomas Shenk
Functional map of human cytomegalovirus AD169 defined by global mutational analysis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12396-401.
2003: Maria C Silva; Qian-Chun Yu; Lynn W Enquist; Thomas Shenk
Human cytomegalovirus UL99-encoded pp28 is required for the cytoplasmic envelopment of tegument-associated capsids.
Journal of virology 2003;77(19):10594-605.
2003: Edward P Browne; Thomas Shenk
Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11439-44.
2003: Isidore Rigoutsos; Jiri Novotny; Tien Huynh; Stephen T Chin-Bow; Laxmi Parida; Daniel Platt; David Coleman; Thomas Shenk
In silico pattern-based analysis of the human cytomegalovirus genome.
Journal of virology 2003;77(7):4326-44.
2003: Robert F Kalejta; Thomas Shenk
Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3263-8.
2003: Robert F Kalejta; Jill T Bechtel; Thomas Shenk
Human cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors.
Molecular and cellular biology 2003;23(6):1885-95.
2003: Robert F Kalejta; Thomas Shenk
The human cytomegalovirus UL82 gene product (pp71) accelerates progression through the G1 phase of the cell cycle.
Journal of virology 2003;77(6):3451-9.
2003: Ronald Atlas; Philip Campbell; Nicholas R Cozzarelli; Greg Curfman; Lynn Enquist; Gerald Fink; Annette Flanagin; Jacqueline Fletcher; Elizabeth George; Gordon Hammes; David Heyman; Thomas Inglesby; Samuel Kaplan; Donald Kennedy; Judith Krug; Rachel Levinson; Emilie Marcus; Henry Metzger; Stephen S Morse; Alison O'Brien; Andrew Onderdonk; George Poste; Beatrice Renault; Robert Rich; ARIELLA ROSENGARD; Steven Salzburg; Mary Scanlan; Thomas Shenk; Herbert Tabor; Harold Varmus; Eckard Wimmer; Keith Yamamoto
Statement on scientific publication and security.
Science (New York, N.Y.) 2003;299(5610):1149.
2003: Ronald Atlas; Philip Campbell; Nicholas R Cozzarelli; Greg Curfman; Lynn Enquist; Gerald Fink; Annette Flanagin; Jacqueline Fletcher; Elizabeth George; Gordon Hammes; David Heyman; Thomas Inglesby; Samuel Kaplan; Donald Kennedy; Judith Krug; Rachel Levinson; Emilie Marcus; Henry Metzger; Stephen S Morse; Alison O'Brien; Andrew Onderdonk; George Poste; Beatrice Renault; Robert Rich; ARIELLA ROSENGARD; Steven L Salzberg; Mary Scanlan; Thomas Shenk; Herbert Tabor; Harold Varmus; Eckard Wimmer; Keith Yamamoto
Statement on the consideration of biodefence and biosecurity.
Nature 2003;421(6925):771.
2003: Ronald Atlas; Philip Campbell; Nicholas R Cozzarelli; Greg Curfman; Lynn Enquist; Gerald Fink; Annette Flanagin; Jacqueline Fletcher; Elizabeth George; Gordon Hammes; David Heyman; Thomas Inglesby; Samuel Kaplan; Donald Kennedy; Judith Krug; Rachel E Levinson; Emilie Marcus; Henry Metzger; Stephen S Morse; Alison O'Brien; Andrew Onderdonk; George Poste; Beatrice Renault; Robert Rich; ARIELLA ROSENGARD; Steven Salzburg; Mary Scanlan; Thomas Shenk; Herbert Tabor; Harold Varmus; Eckard Wimmer; Keith Yamamoto; Steven Salzberg
Uncensored exchange of scientific results.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1464.
2002: Felicia Goodrum; Craig T Jordan; Kevin High; Thomas Shenk
Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16255-60.
2002: Catherine A Blankenship; Thomas Shenk
Mutant human cytomegalovirus lacking the immediate-early TRS1 coding region exhibits a late defect.
Journal of virology 2002;76(23):12290-9.
2002: Thomas Shenk
Might a vanguard of mRNAs prepare cells for the arrival of herpes simplex virus?
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8465-6.
2002: Hua Zhu; Jian-Ping Cong; Deborah Yu; Wade A Bresnahan; Thomas Shenk
Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3932-7.
2002: Julie A Heider; Wade A Bresnahan; Thomas Shenk
Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3141-6.
2002: Dong Yu; Gregory A Smith; Lynn W Enquist; Thomas Shenk
Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene.
Journal of virology 2002;76(5):2316-28.
2002: Jill T Bechtel; Thomas Shenk
Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression.
Journal of virology 2002;76(3):1043-50.
2002: Robert F Kalejta; Thomas Shenk
Manipulation of the cell cycle by human cytomegalovirus.
Frontiers in bioscience : a journal and virtual library 2002;7():d295-306.
2002: Julie A Heider; Yongjun Yu; Thomas Shenk; James C Alwine
Characterization of a human cytomegalovirus with phosphorylation site mutations in the immediate-early 2 protein.
Journal of virology 2002;76(2):928-32.
2002: Sofia A Oliveira; Se-Ho Park; Peter Lee; Albert Bendelac; Thomas Shenk
Murine cytomegalovirus m02 gene family protects against natural killer cell-mediated immune surveillance.
Journal of virology 2002;76(2):885-94.
2001: Edward P Browne; Bret Alan Wing; D Coleman; Thomas Shenk
Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs.
Journal of virology 2001;75(24):12319-30.
2001: J Novotny; Isidore Rigoutsos; D Coleman; Thomas Shenk
In silico structural and functional analysis of the human cytomegalovirus (HHV5) genome.
Journal of molecular biology 2001;310(5):1151-66.
2001: V Petkova; MJ Romanowski; Indra Sulijoadikusumo; D Rohne; Patrick Kang; Thomas Shenk; Anny Usheva
Interaction between YY1 and the retinoblastoma protein. Regulation of cell cycle progression in differentiated cells.
The Journal of biological chemistry 2001;276(11):7932-6.
2001: S A Oliveira; Thomas Shenk
Murine cytomegalovirus M78 protein, a G protein-coupled receptor homologue, is a constituent of the virion and facilitates accumulation of immediate-early viral mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3237-42.
2000: Wade A Bresnahan; Thomas Shenk
UL82 virion protein activates expression of immediate early viral genes in human cytomegalovirus-infected cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14506-11.
2000: G E Tullis; Thomas Shenk
Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size.
Journal of virology 2000;74(24):11511-21.
2000: Wade A Bresnahan; G E Hultman; Thomas Shenk
Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts.
Journal of virology 2000;74(22):10816-8.
2000: Wade A Bresnahan; Thomas Shenk
A subset of viral transcripts packaged within human cytomegalovirus particles.
Science (New York, N.Y.) 2000;288(5475):2373-6.
2000: M L Hayashi; C Blankenship; Thomas Shenk
Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2692-6.
1999: C E Patterson; Thomas Shenk
Human cytomegalovirus UL36 protein is dispensable for viral replication in cultured cells.
Journal of virology 1999;73(9):7126-31.
1999: Nobuo Horikoshi; JP Cong; N Kley; Thomas Shenk
Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.
Biochemical and biophysical research communications 1999;261(3):864-9.
1999: Darby L Thomas; S Shin; B H Jiang; H Vogel; M A Ross; Michael Gordon Kaplitt; Thomas Shenk; Ronald T Javier
Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9.
Journal of virology 1999;73(4):3071-9.
1999: M Lu; Thomas Shenk
Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle.
Journal of virology 1999;73(1):676-83.
1999: Alec J Hirsch; Thomas Shenk
Human cytomegalovirus inhibits transcription of the CC chemokine MCP-1 gene.
Journal of virology 1999;73(1):404-10.
1998: F Higashino; James M Pipas; Thomas Shenk
Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15683-7.
1998: H Zhu; JP Cong; G Mamtora; Thomas Gingeras; Thomas Shenk
Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14470-5.
1998: S Gabler; H Schütt; Peter Groitl; Hans Wolf; Thomas Shenk; Thomas Dobner
E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs.
Journal of virology 1998;72(10):7960-71.
1998: C L Parks; P S Robinson; Etienne Sibille; Thomas Shenk; Miklos Toth
Increased anxiety of mice lacking the serotonin1A receptor.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10734-9.
1998: J Roth; M Dobbelstein; DA Freedman; Thomas Shenk; Arnold J Levine
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
The EMBO journal 1998;17(2):554-64.
1997: H Zhu; JP Cong; Thomas Shenk
Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13985-90.
1997: Robert F Kalejta; Thomas Shenk; Andrew Beavis
Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry.
Cytometry 1997;29(4):286-91.
1997: C L Parks; Thomas Shenk
Activation of the adenovirus major late promoter by transcription factors MAZ and Sp1.
Journal of virology 1997;71(12):9600-7.
1997: M Dobbelstein; J Roth; W T Kimberly; Arnold J Levine; Thomas Shenk
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence.
The EMBO journal 1997;16(14):4276-84.
1997: MJ Romanowski; E Garrido-Guerrero; Thomas Shenk
pIRS1 and pTRS1 are present in human cytomegalovirus virions.
Journal of virology 1997;71(7):5703-5.
1997: C J Baldick; A Marchini; C E Patterson; Thomas Shenk
Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle.
Journal of virology 1997;71(6):4400-8.
1997: Y Shen; H Zhu; Thomas Shenk
Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3341-5.
1997: MJ Romanowski; Thomas Shenk
Characterization of the human cytomegalovirus irs1 and trs1 genes: a second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation.
Journal of virology 1997;71(2):1485-96.
1997: J Flint; Thomas Shenk
Viral transactivating proteins.
Annual review of genetics 1997;31():177-212.
1996: M Lu; Thomas Shenk
Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S.
Journal of virology 1996;70(12):8850-7.
1996: H B Houbaviy; A Usheva; Thomas Shenk; Stephen K Burley
Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):13577-82.
1996: A Usheva; Thomas Shenk
YY1 transcriptional initiator: protein interactions and association with a DNA site containing unpaired strands.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):13571-6.
1996: M Moore; Nobuo Horikoshi; Thomas Shenk
Oncogenic potential of the adenovirus E4orf6 protein.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11295-301.
1996: Zhao-Yi Wang; Q Q Qiu; W Seufert; T Taguchi; J R Testa; S A Whitmore; D F Callen; D Welsh; Thomas Shenk; T F Deuel
Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9.
The Journal of biological chemistry 1996;271(40):24811-6.
1996: M Dobbelstein; Thomas Shenk
Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product.
Journal of virology 1996;70(9):6479-85.
1996: Felicia D Goodrum; Thomas Shenk; David A Ornelles
Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells.
Journal of virology 1996;70(9):6323-35.
1996: C J Baldick; Thomas Shenk
Proteins associated with purified human cytomegalovirus particles.
Journal of virology 1996;70(9):6097-105.
1996: B Elenbaas; M Dobbelstein; J Roth; Thomas Shenk; Arnold J Levine
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain.
Molecular medicine (Cambridge, Mass.) 1996;2(4):439-51.
1996: Thomas Dobner; Nobuo Horikoshi; S Rubenwolf; Thomas Shenk
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor.
Science (New York, N.Y.) 1996;272(5267):1470-3.
1996: F K Ferrari; T Samulski; Thomas Shenk; R Jude Samulski
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors.
Journal of virology 1996;70(5):3227-34.
1996: C L Parks; Thomas Shenk
The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1.
The Journal of biological chemistry 1996;271(8):4417-30.
1996: Ronald T Javier; Thomas Shenk
Mammary tumors induced by human adenovirus type 9: a role for the viral early region 4 gene.
Breast cancer research and treatment 1996;39(1):57-67.
1995: M Dobbelstein; Thomas Shenk
In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA libraries.
Journal of virology 1995;69(12):8027-34.
1995: Hua Zhu; Y Shen; Thomas Shenk
Human cytomegalovirus IE1 and IE2 proteins block apoptosis.
Journal of virology 1995;69(12):7960-70.
1995: R P Hyde-DeRuyscher; Ezra Jennings; Thomas Shenk
DNA binding sites for the transcriptional activator/repressor YY1.
Nucleic acids research 1995;23(21):4457-65.
1995: M Toth; Thomas Shenk; E Madarasz
Differentiation is induced in three-dimensional cultures of brain cells immortalized by the LAP mammalian regulatory system.
Journal of neuroscience research 1995;41(6):764-74.
1995: B A Lewis; G Tullis; E Seto; Nobuo Horikoshi; roberto weinmann; Thomas Shenk
Adenovirus E1A proteins interact with the cellular YY1 transcription factor.
Journal of virology 1995;69(3):1628-36.
1995: Y Shen; Thomas Shenk
Viruses and apoptosis.
Current opinion in genetics & development 1995;5(1):105-11.
1995: Nobuo Horikoshi; A Usheva; Jiandong Chen; Arnold J Levine; roberto weinmann; Thomas Shenk
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression.
Molecular and cellular biology 1995;15(1):227-34.
1994: M Toth; D Ding; Thomas Shenk
The 5' flanking region of the serotonin 2 receptor gene directs brain specific expression in transgenic animals.
Brain research. Molecular brain research 1994;27(2):315-9.
1994: C C MacDonald; Jeffrey Wilusz; Thomas Shenk
The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location.
Molecular and cellular biology 1994;14(10):6647-54.
1994: Y Wang; D M Albert; Thomas Shenk
Adenovirus E1A expression controlled by the red pigment promoter in transgenic mice: a model for developmental abnormalities of the eye.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(10):1061-8.
1994: Y Shen; Thomas Shenk
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8940-4.
1994: M Toth; Thomas Shenk
Antagonist-mediated down-regulation of 5-hydroxytryptamine type 2 receptor gene expression: modulation of transcription.
Molecular pharmacology 1994;45(6):1095-100.
1994: A Usheva; Thomas Shenk
TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA.
Cell 1994;76(6):1115-21.
1993: T Kleinberger; Thomas Shenk
Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription.
Journal of virology 1993;67(12):7556-60.
1993: D Ding; M Toth; Y Zhou; C Parks; B J Hoffman; Thomas Shenk
Glial cell-specific expression of the serotonin 2 receptor gene: selective reactivation of a repressed promoter.
Brain research. Molecular brain research 1993;20(3):181-91.
1993: E Seto; B Lewis; Thomas Shenk
Interaction between transcription factors Sp1 and YY1.
Nature 1993;365(6445):462-4.
1993: P H Chen; D A Ornelles; Thomas Shenk
The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells.
Journal of virology 1993;67(6):3507-14.
1992: E Seto; A Usheva; G P Zambetti; Jamil Momand; Nobuo Horikoshi; roberto weinmann; Arnold J Levine; Thomas Shenk
Wild-type p53 binds to the TATA-binding protein and represses transcription.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):12028-32.
1992: M Toth; W Doerfler; Thomas Shenk
Adenovirus DNA replication facilitates binding of the MLTF/USF transcription factor to the viral major late promoter within infected cells.
Nucleic acids research 1992;20(19):5143-8.
1992: T B Hasson; D A Ornelles; Thomas Shenk
Adenovirus L1 52- and 55-kilodalton proteins are present within assembling virions and colocalize with nuclear structures distinct from replication centers.
Journal of virology 1992;66(10):6133-42.
1992: U Müller; T Kleinberger; Thomas Shenk
Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1.
Journal of virology 1992;66(10):5867-78.
1992: R Javier; K Raska; Thomas Shenk
Requirement for the adenovirus type 9 E4 region in production of mammary tumors.
Science (New York, N.Y.) 1992;257(5074):1267-71.
1992: Y Takagaki; C C MacDonald; Thomas Shenk; James L Manley
The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1403-7.
1991: T Kleinberger; Thomas Shenk
A protein kinase is present in a complex with adenovirus E1A proteins.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11143-7.
1991: C L Parks; Long-sheng Chang; Thomas Shenk
A polymerase chain reaction mediated by a single primer: cloning of genomic sequences adjacent to a serotonin receptor protein coding region.
Nucleic acids research 1991;19(25):7155-60.
1991: P Rigby; Thomas Shenk
Paul Berg, on his 65th birthday.
Nucleic acids research 1991;19(25):7041.
1991: E Seto; Yigong Shi; Thomas Shenk
YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro.
Nature 1991;354(6350):241-5.
1991: Michael B Mathews; Thomas Shenk
Adenovirus virus-associated RNA and translation control.
Journal of virology 1991;65(11):5657-62.
1991: Yigong Shi; E Seto; Long-sheng Chang; Thomas Shenk
Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein.
Cell 1991;67(2):377-88.
1991: E A Montalvo; Yigong Shi; Thomas Shenk; Arnold J Levine
Negative regulation of the BZLF1 promoter of Epstein-Barr virus.
Journal of virology 1991;65(7):3647-55.
1991: S B Baim; M A Labow; Arnold J Levine; Thomas Shenk
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5072-6.
1991: R Javier; K Raska; G J Macdonald; Thomas Shenk
Human adenovirus type 9-induced rat mammary tumors.
Journal of virology 1991;65(6):3192-202.
1991: E Vakalopoulou; Jerome Schaack; Thomas Shenk
A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.
Molecular and cellular biology 1991;11(6):3355-64.
1991: D A Engel; U Muller; R W Gedrich; J S Eubanks; Thomas Shenk
Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3957-61.
1991: Jerome Schaack; J Logan; E Vakalopoulou; Thomas Shenk
Adenovirus E1A protein activates transcription of the E1A gene subsequent to transcription complex formation.
Journal of virology 1991;65(4):1687-94.
1991: Thomas Shenk; J Flint
Transcriptional and transforming activities of the adenovirus E1A proteins.
Advances in cancer research 1991;57():47-85.
1991: D A Ornelles; Thomas Shenk
Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein.
Journal of virology 1991;65(1):424-9.
1990: Y Takagaki; James L Manley; C C MacDonald; Jeffrey Wilusz; Thomas Shenk
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.
Genes & development 1990;4(12A):2112-20.
1990: Jeffrey Wilusz; Thomas Shenk
A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal.
Molecular and cellular biology 1990;10(12):6397-407.
1990: Jerome Schaack; W Y Ho; P Freimuth; Thomas Shenk
Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA.
Genes & development 1990;4(7):1197-208.
1990: M A Labow; S B Baim; Thomas Shenk; Arnold J Levine
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells.
Molecular and cellular biology 1990;10(7):3343-56.
1990: Long-sheng Chang; Thomas Shenk
The adenovirus DNA-binding protein stimulates the rate of transcription directed by adenovirus and adeno-associated virus promoters.
Journal of virology 1990;64(5):2103-9.
1990: M J Marton; S B Baim; D A Ornelles; Thomas Shenk
The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.
Journal of virology 1990;64(5):2345-59.
1990: J Schaak; Paul Schedl; Thomas Shenk
Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function.
Nucleic acids research 1990;18(6):1499-508.
1990: Jeffrey Wilusz; Thomas Shenk; Y Takagaki; James L Manley
A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates.
Molecular and cellular biology 1990;10(3):1244-8.
1990: P D Soloway; Thomas Shenk
The adenovirus type 5 i-leader open reading frame functions in cis to reduce the half-life of L1 mRNAs.
Journal of virology 1990;64(2):551-8.
1990: J Schaack; P Schedl; Thomas Shenk
Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication.
Journal of virology 1990;64(1):78-85.
1989: U Müller; M P Roberts; D A Engel; W Doerfler; Thomas Shenk
Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP.
Genes & development 1989;3(12A):1991-2002.
1989: D Urbanelli; Y Sawada; J Raskova; N C Jones; Thomas Shenk; K Raska
C-terminal domain of the adenovirus E1A oncogene product is required for induction of cytotoxic T lymphocytes and tumor-specific transplantation immunity.
Virology 1989;173(2):607-14.
1989: S Hardy; Thomas Shenk
E2F from adenovirus-infected cells binds cooperatively to DNA containing two properly oriented and spaced recognition sites.
Molecular and cellular biology 1989;9(10):4495-506.
1989: T B Hasson; P D Soloway; D A Ornelles; W Doerfler; Thomas Shenk
Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions.
Journal of virology 1989;63(9):3612-21.
1989: R Jude Samulski; Long-sheng Chang; Thomas Shenk
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression.
Journal of virology 1989;63(9):3822-8.
1989: Long-sheng Chang; Yigong Shi; Thomas Shenk
Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor.
Journal of virology 1989;63(8):3479-88.
1989: Keith Leppard; Thomas Shenk
The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism.
The EMBO journal 1989;8(8):2329-36.
1989: S Hardy; D A Engel; Thomas Shenk
An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity.
Genes & development 1989;3(7):1062-74.
1989: Jeffrey Wilusz; S M Pettine; Thomas Shenk
Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal.
Nucleic acids research 1989;17(10):3899-908.
1989: J Schaack; Thomas Shenk
Adenovirus terminal protein mediates efficient and timely activation of viral transcription.
Current topics in microbiology and immunology 1989;144():185-90.
1989: J Flint; Thomas Shenk
Adenovirus E1A protein paradigm viral transactivator.
Annual review of genetics 1989;23():141-61.
1988: D A Engel; S Hardy; Thomas Shenk
cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A.
Genes & development 1988;2(12A):1517-28.
1988: Jeffrey Wilusz; D I Feig; Thomas Shenk
The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites.
Molecular and cellular biology 1988;8(10):4477-83.
1988: Y Sawada; K Raska; Thomas Shenk
Adenovirus type 5 and adenovirus type 12 recombinant viruses containing heterologous E1 genes are viable, transform rat cells, but are not tumorigenic in rats.
Virology 1988;166(1):281-4.
1988: S Hardy; Thomas Shenk
Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4171-5.
1988: M A Moore; Thomas Shenk
The adenovirus tripartite leader sequence can alter nuclear and cytoplasmic metabolism of a non-adenovirus mRNA within infected cells.
Nucleic acids research 1988;16(5):2247-62.
1988: Fern Barkalow; D E Birk; Thomas Shenk; K Raska
Tumorigenicity of adenovirus-transformed cells: collagen interaction and cell surface laminin are controlled by the serotype origin of the E1A and E1B genes.
Journal of virology 1988;62(2):580-5.
1988: Jeffrey Wilusz; Thomas Shenk
A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif.
Cell 1988;52(2):221-8.
1988: R Jude Samulski; Thomas Shenk
Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs.
Journal of virology 1988;62(1):206-10.
1987: J Logan; E Falck-Pedersen; J E Darnell; Thomas Shenk
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8306-10.
1987: M Moore; Jerome Schaack; S B Baim; R I Morimoto; Thomas Shenk
Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells.
Molecular and cellular biology 1987;7(12):4505-12.
1987: R Jude Samulski; Long-sheng Chang; Thomas Shenk
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication.
Journal of virology 1987;61(10):3096-101.
1987: P Hearing; R Jude Samulski; W L Wishart; Thomas Shenk
Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome.
Journal of virology 1987;61(8):2555-8.
1987: J R Cutt; Thomas Shenk; P Hearing
Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells.
Journal of virology 1987;61(2):543-52.
1987: R J Schneider; Thomas Shenk
Impact of virus infection on host cell protein synthesis.
Annual review of biochemistry 1987;56():317-32.
1986: J Kitajewski; R J Schneider; B Safer; Thomas Shenk
An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines.
Molecular and cellular biology 1986;6(12):4493-8.
1986: J Resnick; Thomas Shenk
Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus.
Journal of virology 1986;60(3):1098-106.
1986: J Logan; Thomas Shenk
In vivo identification of sequence elements required for normal function of the adenovirus major late transcriptional control region.
Nucleic acids research 1986;14(15):6327-35.
1986: J D Welsh; C Swimmer; T Cocke; Thomas Shenk
A second domain of simian virus 40 T antigen in which mutations can alter the cellular localization of the antigen.
Molecular and cellular biology 1986;6(6):2207-12.
1986: J Kitajewski; R J Schneider; B Safer; S M Munemitsu; C E Samuel; B Thimmappaya; Thomas Shenk
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase.
Cell 1986;45(2):195-200.
1986: P Hearing; Thomas Shenk
The adenovirus type 5 E1A enhancer contains two functionally distinct domains: one is specific for E1A and the other modulates all early units in cis.
Cell 1986;45(2):229-36.
1986: Y Sawada; D Urbanelli; J Raskova; Thomas Shenk; K Raska
Adenovirus tumor-specific transplantation antigen is a function of the E1A early region.
The Journal of experimental medicine 1986;163(3):563-72.
1986: S Pilder; M Moore; J Logan; Thomas Shenk
The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs.
Molecular and cellular biology 1986;6(2):470-6.
1985: Y Sawada; B Föhring; Thomas Shenk; K Raska
Tumorigenicity of adenovirus-transformed cells: region E1A of adenovirus 12 confers resistance to natural killer cells.
Virology 1985;147(2):413-21.
1985: C Swimmer; Thomas Shenk
Selection of sequence elements that substitute for the standard AATAAA motif which signals 3' processing and polyadenylation of late simian virus 40 mRNAs.
Nucleic acids research 1985;13(22):8053-63.
1985: P Hearing; Thomas Shenk
Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit.
Molecular and cellular biology 1985;5(11):3214-21.
1985: D N Halbert; J R Cutt; Thomas Shenk
Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff.
Journal of virology 1985;56(1):250-7.
1985: R J Schneider; B Safer; S M Munemitsu; C E Samuel; Thomas Shenk
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(13):4321-5.
1985: E Falck-Pedersen; J Logan; Thomas Shenk; J E Darnell
Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element.
Cell 1985;40(4):897-905.
1985: N I Hutchinson; Long-sheng Chang; M M Pater; N Bouck; Thomas Shenk; G di Mayorca
Characterization of a new simian virus 40 mutant, tsA3900, isolated from deletion mutant tsA1499.
Journal of virology 1985;53(3):814-21.
1984: S Pilder; J Logan; Thomas Shenk
Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA.
Journal of virology 1984;52(2):664-71.
1984: C Swimmer; Thomas Shenk
A viable simian virus 40 variant that carries a newly generated sequence reiteration in place of the normal duplicated enhancer element.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(21):6652-6.
1984: G Winberg; Thomas Shenk
Dissection of overlapping functions within the adenovirus type 5 E1A gene.
The EMBO journal 1984;3(8):1907-12.
1984: J Logan; Thomas Shenk
Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3655-9.
1984: R J Schneider; C Weinberger; Thomas Shenk
Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells.
Cell 1984;37(1):291-8.
1984: P Sarnow; P Hearing; C W Anderson; D N Halbert; Thomas Shenk; Arnold J Levine
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells.
Journal of virology 1984;49(3):692-700.
1984: Thomas Shenk; J Williams
Genetic analysis of adenoviruses.
Current topics in microbiology and immunology 1984;111():1-39.
1983: P Hearing; Thomas Shenk
Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs.
Journal of molecular biology 1983;167(4):809-22.
1983: P Hearing; Thomas Shenk
The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element.
Cell 1983;33(3):695-703.
1982: J S Logan; Thomas Shenk
Transcriptional and translational control of adenovirus gene expression.
Microbiological reviews 1982;46(4):377-83.
1982: B Thimmappaya; C Weinberger; R J Schneider; Thomas Shenk
Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection.
Cell 1982;31(3 Pt 2):543-51.
1982: W W Colby; Thomas Shenk
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5189-93.
1981: J Logan; J C Nicolas; W C Topp; M Girard; Thomas Shenk; Arnold J Levine
Transformation by adenovirus early region 2A temperature-sensitive mutants and their revertants.
Virology 1981;115(2):419-22.
1981: W W Colby; Thomas Shenk
Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX.
Journal of virology 1981;39(3):977-80.
1981: M Fitzgerald; Thomas Shenk
The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs.
Cell 1981;24(1):251-60.
1981: Thomas Shenk
Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III.
Current topics in microbiology and immunology 1981;93():25-46.
1980: D M Fowlkes; Thomas Shenk
Transcriptional control regions of the adenovirus VAI RNA gene.
Cell 1980;22(2 Pt 2):405-13.
1980: B R Dhruva; Thomas Shenk; K N Subramanian
Integration in vivo into simian virus 40 DNA of a sequence that resembles a certain family of genomic interspersed repeated sequences.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(8):4514-8.
1980: R S Galos; J Williams; Thomas Shenk; N Jones
Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping.
Virology 1980;104(2):510-3.
1980: S R Ross; Arnold J Levine; R S Galos; J Williams; Thomas Shenk
Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants.
Virology 1980;103(2):475-92.
1980: Thomas Shenk; N Jones; W Colby; D Fowlkes
Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 1,():367-75.
1980: D Pintel; N Bouck; G di Mayorca; B Thimmappaya; B Swerdlow; Thomas Shenk
SV40 mutant tsA1499 is heat-sensitive for lytic growth but generates cold-sensitive rat-cell transformants.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 1,():305-9.
1980: M Fitzgerald; Thomas Shenk
The site at which late mRNAs are polyadenylated is altered in SV40 mutant dl882.
Annals of the New York Academy of Sciences 1980;354():53-9.
1979: B Thimmappaya; N Jones; Thomas Shenk
A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome.
Cell 1979;18(4):947-54.
1979: N Jones; Thomas Shenk
An adenovirus type 5 early gene function regulates expression of other early viral genes.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(8):3665-9.
1979: N Jones; Thomas Shenk
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells.
Cell 1979;17(3):683-9.
1979: B Thimmappaya; Thomas Shenk
Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen.
Journal of virology 1979;30(3):668-73.
1978: K N Subramanian; Thomas Shenk
Definition of the boundaries of the origin of DNA replication in simian virus 40.
Nucleic acids research 1978;5(10):3635-42.
1978: N Bouck; N Beales; Thomas Shenk; Paul Berg; G di Mayorca
New region of the simian virus 40 genome required for efficient viral transformation.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(5):2473-7.
1978: Thomas Shenk
Construction of a viable SV40 variant containing two functional origins of DNA replication.
Cell 1978;13(4):791-8.
1978: N Jones; Thomas Shenk
Isolation of deletion and substitution mutants of adenovirus type 5.
Cell 1978;13(1):181-8.
1977: R W Schlesinger; V Stollar; G M Guild; A Igarashi; Thomas Shenk; J Peleg
The significance and nature of defective interfering viruses.
Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften 1977;33(4-6):229-42.
1977: Thomas Shenk
A biochemical method for increasing the size of deletion mutations in simian virus 40 DNA.
Journal of molecular biology 1977;113(3):503-15.
1976: Thomas Shenk; Paul Berg
Isolation and propagation of a segment of the simian virus 40 genome containing the origin of DNA replication.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(5):1513-7.
1976: Thomas Shenk; J Carbon; Paul Berg
Construction and analysis of viable deletion mutants of simian virus 40.
Journal of virology 1976;18(2):664-71.
1975: J Carbon; Thomas Shenk; Paul Berg
Construction in vitro of mutants of simian virus 40: insertion of a poly(dA-dT) segment at the Hemophilus parainfluenza II restriction endonuclease cleavage site.
Journal of molecular biology 1975;98(1):1-15.
1975: J Carbon; Thomas Shenk; Paul Berg
Biochemical procedure for production of small deletions in simian virus 40 DNA.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(4):1392-6.
1975: Thomas Shenk; C Rhodes; P W Rigby; Paul Berg
Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(3):989-93.
1975: V Stollar; Thomas Shenk; R Koo; A Igarashi; R W Schlesinger
Observations of Aedes albopictus cell cultures persistently infected with Sindbis virus.
Annals of the New York Academy of Sciences 1975;266():214-31.
1975: Thomas Shenk; C Rhodes; P W Rigby; Paul Berg
Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 1():61-7.
1974: Thomas Shenk; K A Koshelnyk; V Stollar
Temperature-sensitive virus from Aedes albopictus cells chronically infected with Sindbis virus.
Journal of virology 1974;13(2):439-47.
1973: Thomas Shenk; V Stollar
Defective-interfering particles of Sindbis virus. II. Homologous interference.
Virology 1973;55(2):530-4.
1973: Thomas Shenk; V Stollar
Defective-interfering particles of Sindbis virus. I. Isolation and some chemical and biological properties.
Virology 1973;53(1):162-73.
1973: V Stollar; Thomas Shenk
Homologous viral interference in Aedes albopictus cultures chronically infected with Sindbis virus.
Journal of virology 1973;11(4):592-5.
1972: Thomas Shenk; V Stollar
Effect of double-stranded RNAs from Sindbis virus-infected cells on rabbit reticulocyte and chick embryo cell-free protein synthesis.
Biochimica et biophysica acta 1972;287(3):501-13.
1972: Thomas Shenk; V Stollar
Viral RNA species in BHK-21 cells infected with Sindbis virus serially passaged at high multiplicity of infection.
Biochemical and biophysical research communications 1972;49(1):60-7.
1972: V Stollar; Thomas Shenk; B D Stollar
Double-stranded RNA in hamster, chick, and mosquito cells infected with Sindbis virus.
Virology 1972;47(1):122-32.
1971: P J Wood; J Podlewski; Thomas Shenk
Cytochemical observations of hemolymph cells during coagulation in the crayfish, Orconectes virilis.
Journal of morphology 1971;134(4):479-87.
1971: V Stollar; T M Stevens; Thomas Shenk
3. RNA of uninfected and Sindbis virus-infected Aedes albopictus cells.
Current topics in microbiology and immunology 1971;55():164-9.
1970: P F Forsthoefel; Thomas Shenk
Linkage relationships of Strong's luxoid gene in the mouse.
The Journal of heredity 1970;61(2):64-6.