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Haynes Sheppard

Research Profile

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HIV-1

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Stephanie Planque; Yukie Mitsuda; Hiroaki Taguchi; Maria Salas; Mary-Kate Morris; Yasuhiro Nishiyama; Robert Kyle; Pablo C Okhuysen; Miguel Escobar; Robert Hunter; Haynes W Sheppard; Carl Hanson; Sudhir Paul
Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection.
Cecilia Rademeyer; Penny L Moore; Natasha Taylor; Darren Martin; Isaac A Choge; Elin S Gray; Haynes W Sheppard; Clive Gray; Lynn Morris; Carolyn Williamson
Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies.
Kiersten A Israel-Ballard; Richard M Donovan; Caroline J Chantry; Anna Coutsoudis; Haynes W Sheppard; Lindiwe Sibeko; Barbara Abrams
Flash-heat inactivation of HIV-1 in human milk: a potential method to reduce postnatal transmission in developing countries.

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2007: Stephanie Planque; Yukie Mitsuda; Hiroaki Taguchi; Maria Salas; Mary-Kate Morris; Yasuhiro Nishiyama; Robert Kyle; Pablo C Okhuysen; Miguel Escobar; Robert Hunter; Haynes W Sheppard; Carl Hanson; Sudhir Paul
Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection.
AIDS research and human retroviruses 2007;23(12):1541-54.
2007: Cecilia Rademeyer; Penny L Moore; Natasha Taylor; Darren Martin; Isaac A Choge; Elin S Gray; Haynes W Sheppard; Clive Gray; Lynn Morris; Carolyn Williamson
Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies.
Virology 2007;368(1):172-81.
2007: Kiersten A Israel-Ballard; Richard M Donovan; Caroline J Chantry; Anna Coutsoudis; Haynes W Sheppard; Lindiwe Sibeko; Barbara Abrams
Flash-heat inactivation of HIV-1 in human milk: a potential method to reduce postnatal transmission in developing countries.
Journal of acquired immune deficiency syndromes (1999) 2007;45(3):318-23.
2007: Helba Bredell; Darren Martin; Joanne H van Harmelen; Arvind Varsani; Haynes W Sheppard; Richard Donovan; Clive Gray; Carolyn Williamson
HIV type 1 subtype C gag and nef diversity in Southern Africa.
AIDS research and human retroviruses 2007;23(3):477-81.
2006: Tara M Riddle; Norah Shire; Marc Sherman; Kelly F Franco; Haynes W Sheppard; Julie A E Nelson
Sequential turnover of human immunodeficiency virus type 1 env throughout the course of infection.
Journal of virology 2006;80(21):10591-9.
2006: Kiersten A Israel-Ballard; Caroline J Chantry; Kathryn G Dewey; Richard M Donovan; Haynes W Sheppard; Barbara Abrams
Heat treating breast milk as an infant feeding option.
Journal of human lactation : official journal of International Lactation Consultant Association 2006;22(3):267-8; author reply 268.
2006: Moira Vignoles; María M Avila; María Luz Osimani; María de Los Angeles Pando; Diana Rossi; Haynes W Sheppard; Sergio Sosa-Estani; Jorge Benetucci; Sergio Maulen; Héctor Chiparelli; José Russi; José Luis Sánchez; Silvia M Montano; Liliana Martínez-Peralta; Mercedes Weissenbacher
HIV seroincidence estimates among at-risk populations in Buenos Aires and Montevideo: use of the serologic testing algorithm for recent HIV seroconversion.
Journal of acquired immune deficiency syndromes (1999) 2006;42(4):494-500.
2006: Caroline J Chantry; Barbara Abrams; Richard M Donovan; Kiersten A Israel-Ballard; Haynes W Sheppard
Breast milk pasteurization: appropriate assays to detect HIV inactivation.
Infectious diseases in obstetrics and gynecology 2006;2006():95938.
2005: Kiersten A Israel-Ballard; Caroline J Chantry; Kathryn Dewey; Bo Lonnerdal; Haynes W Sheppard; Richard M Donovan; James Carlson; Allyson Sage; Barbara Abrams
Viral, nutritional, and bacterial safety of flash-heated and pretoria-pasteurized breast milk to prevent mother-to-child transmission of HIV in resource-poor countries: a pilot study.
Journal of acquired immune deficiency syndromes (1999) 2005;40(2):175-81.
2005: Haynes W Sheppard
Inactivated- or killed-virus HIV/AIDS vaccines.
Current drug targets. Infectious disorders 2005;5(2):131-41.
2005: Clive Gray; Carolyn Williamson; Helba Bredell; Adrian Puren; Xiaohua Xia; Ruben Filter; Lynn S Zijenah; Huyen Cao; Lynn Morris; Eftyhia Vardas; Mark Colvin; Glenda Gray; James McIntyre; ROSEMARY MUSONDA; Susan Allen; David Katzenstein; Mike Mbizo; Newton Kumwenda; Taha E Taha; Salim Abdool Karim; Jorge Flores; Haynes W Sheppard
Viral dynamics and CD4+ T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa.
AIDS research and human retroviruses 2005;21(4):285-91.
2005: Carmem A de Freitas Oliveira; Mirthes Ueda; Rosemeire Yamashiro; Rosângela Rodrigues; Haynes W Sheppard; Luís Fernando de Macedo Brígido
Rate and incidence estimates of recent human immunodeficiency virus type 1 infections among pregnant women in Sao Paulo, Brazil, from 1991 to 2002.
Journal of clinical microbiology 2005;43(3):1439-42.
2004: Agatha Masemola; Tumelo Mashishi; Greg Khoury; Helba Bredell; Maria Paximadis; Tiyani Mathebula; Debra Barkhan; Adrian Puren; Eftyhia Vardas; Mark Colvin; Lynn S Zijenah; David Katzenstein; ROSEMARY MUSONDA; Susan Allen; Newton Kumwenda; Taha E Taha; Glenda Gray; James McIntyre; Salim Abdool Karim; Haynes W Sheppard; Clive Gray
Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4607-17.
2004: Punnee Pitisuttithum; Phillip W. Berman; Benjaluck Phonrat; Pravan Suntharasamai; Suwanee Raktham; La-ong Srisuwanvilai; Krit Hirunras; Dwip Kitayaporn; Jaranit Kaewkangwal; Sricharoen Migasena; Haynes W Sheppard; Elizabeth Li; Marlene Chernow; Michael L Peterson; Riri Shibata; William L Heyward; Donald P Francis
Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1.
Journal of acquired immune deficiency syndromes (1999) 2004;37(1):1160-5.
2004: Deborah Lee; Barney S Graham; Ya-Lin Chiu; Peter B Gilbert; M Juliana McElrath; Robert B Belshe; Susan P Buchbinder; Haynes W Sheppard; Beryl A Koblin; Kenneth H Mayer; Michael C Keefer; Mark MULLIGAN; Connie Celum
Breakthrough infections during phase 1 and 2 prime-boost HIV-1 vaccine trials with canarypox vectors (ALVAC) and booster dose of recombinant gp120 or gp160.
The Journal of infectious diseases 2004;190(5):903-7.
2004: Alex Espinosa; Moira Vignoles; Manuel Gómez Carrillo; Haynes W Sheppard; Richard Donovan; Liliana Martínez Peralta; Diana Rossi; Graciela Radulich; Horacio Salomón; Mercedes Weissenbacher
Intersubtype BF recombinants of HIV-1 in a population of injecting drug users in Argentina.
Journal of acquired immune deficiency syndromes (1999) 2004;36(1):630-6.
2004: Agatha Masemola; Tumelo Mashishi; Greg Khoury; Phineas Mohube; Pauline Mokgotho; Eftyhia Vardas; Mark Colvin; Lynn S Zijenah; David Katzenstein; ROSEMARY MUSONDA; Susan Allen; Newton Kumwenda; Taha E Taha; Glenda Gray; James McIntyre; Salim Abdool Karim; Haynes W Sheppard; Clive Gray
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.
Journal of virology 2004;78(7):3233-43.
2003: Phalguni Gupta; Lawrence Kingsley; Haynes W Sheppard; Lee H Harrison; Ramdas Chatterjee; Adhir Ghosh; Pratima Roy; Dhruba K Neogi
High incidence and prevalence of HIV-1 infection in high risk population in Calcutta, India.
International journal of STD & AIDS 2003;14(7):463-8.
2003: Bhupat D Rawal; Azucena Degula; Ludmila Lebedeva; Robert S Janssen; Frederick Hecht; Haynes W Sheppard; Michael P Busch
Development of a new less-sensitive enzyme immunoassay for detection of early HIV-1 infection.
Journal of acquired immune deficiency syndromes (1999) 2003;33(3):349-55.
2003: Stephanie A Mulherin; Thomas R O'Brien; John Ioannidis; James J Goedert; Susan P Buchbinder; Roel A Coutinho; Beth D Jamieson; Laurence Meyer; Nelson L Michael; Giuseppe Pantaleo; G Paolo Rizzardi; Hanneke Schuitemaker; Haynes W Sheppard; Ioannis D Theodorou; David Vlahov; Philip S Rosenberg
Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection.
AIDS (London, England) 2003;17(3):377-87.
2002: Eleanor Gouws; Brian Williams; Haynes W Sheppard; Barryett Enge; Salim Abdool Karim
High incidence of HIV-1 in South Africa using a standardized algorithm for recent HIV seroconversion.
Journal of acquired immune deficiency syndromes (1999) 2002;29(5):531-5.
2002: Haynes W Sheppard; Connie Celum; Nelson L Michael; Stephen O'Brien; Michael Dean; Mary Carrington; Dale Dondero; Susan P Buchbinder
HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion.
Journal of acquired immune deficiency syndromes (1999) 2002;29(3):307-13.
2001: S A Lee; R Orque; P A Escarpe; Michael L Peterson; J W Good; E M Zaharias; Phillip W. Berman; Haynes W Sheppard; Riri Shibata
Vaccine-induced antibodies to the native, oligomeric envelope glycoproteins of primary HIV-1 isolates.
Vaccine 2001;20(3-4):563-76.
2001: Michael Marmor; Haynes W Sheppard; Deborah Donnell; Sam Bozeman; Connie Celum; Susan Buchbinder; Beryl A Koblin; George R Seage
Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection.
Journal of acquired immune deficiency syndromes (1999) 2001;27(5):472-81.
2001: Robert B Belshe; C Stevens; Geoffrey J Gorse; Susan Buchbinder; Kent J Weinhold; Haynes W Sheppard; Donald Stablein; S Self; James McNamara; Sharon Frey; J Flores; Jean-Louis Excler; M Klein; R E Habib; AM Duliege; Clayton D Harro; Lawrence Corey; Michael C Keefer; Mark MULLIGAN; P Wright; Connie Celum; Franklyn N Judson; K Mayer; David J McKirnan; Michael Marmor; George E Woody
Safety and immunogenicity of a canarypox-vectored human immunodeficiency virus Type 1 vaccine with or without gp120: a phase 2 study in higher- and lower-risk volunteers.
The Journal of infectious diseases 2001;183(9):1343-52.
2001: Connie Celum; Susan P Buchbinder; Deborah Donnell; John M Douglas; K Mayer; Beryl A Koblin; Michael Marmor; Sam Bozeman; R M Grant; J Flores; Haynes W Sheppard
Early human immunodeficiency virus (HIV) infection in the HIV Network for Prevention Trials Vaccine Preparedness Cohort: risk behaviors, symptoms, and early plasma and genital tract virus load.
The Journal of infectious diseases 2001;183(1):23-35.
2000: Elisa Vicenzi; Silvia Ghezzi; A Brambilla; Haynes W Sheppard; Adriano Lazzarin; Guido Poli; Nelson L Michael
CCR2-64I polymorphism, syncytium-inducing human immunodeficiency virus strains, and disease progression.
The Journal of infectious diseases 2000;182(5):1579-80.
2000: Freya Spielberg; Cathy W Critchlow; Eric Vittinghoff; Anne S Coletti; Haynes W Sheppard; Kenneth H Mayer; D Metzgerg; Franklyn N Judson; Susan Buchbinder; Margaret A Chesney; Michael Gross
Home collection for frequent HIV testing: acceptability of oral fluids, dried blood spots and telephone results. HIV Early Detection Study Group.
AIDS (London, England) 2000;14(12):1819-28.
2000: A Brambilla; C Villa; G Paolo Rizzardi; Fabrizio Veglia; Silvia Ghezzi; Adriano Lazzarin; Marco Cusini; S Muratori; Elena Santagostino; Alessandro Gringeri; Leslie G Louie; Haynes W Sheppard; Guido Poli; Nelson L Michael; Giuseppe Pantaleo; Elisa Vicenzi
Shorter survival of SDF1-3'A/3'A homozygotes linked to CD4+ T cell decrease in advanced human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 2000;182(1):311-5.
2000: W J Fessel; JF Krowka; Haynes W Sheppard; M Gesner; S Tongson; S Weinstein; MS Ascher; S Kwok; C Christopherson
Dissociation of immunologic and virologic responses to highly active antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) 2000;23(4):314-20.
2000: C Christopherson; Y Kidane; B Conway; JF Krowka; Haynes W Sheppard; S Kwok
PCR-Based assay to quantify human immunodeficiency virus type 1 DNA in peripheral blood mononuclear cells.
Journal of clinical microbiology 2000;38(2):630-4.
1999: MR Betts; JF Krowka; Thomas B Kepler; M Davidian; C Christopherson; S Kwok; L Louie; Joseph J Eron; Haynes W Sheppard; Jeffrey Frelinger
Human immunodeficiency virus type 1-specific cytotoxic T lymphocyte activity is inversely correlated with HIV type 1 viral load in HIV type 1-infected long-term survivors.
AIDS research and human retroviruses 1999;15(13):1219-28.
1998: S E Wilson; S L Pedersen; J C Kunich; V L Wilkins; Dean L Mann; G P Mazzara; J Tartaglia; Connie Celum; Haynes W Sheppard
Cross-clade envelope glycoprotein 160-specific CD8+ cytotoxic T lymphocyte responses in early HIV type 1 clade B infection.
AIDS research and human retroviruses 1998;14(11):925-37.
1998: RW Anderson; MS Ascher; Haynes W Sheppard
Direct HIV cytopathicity cannot account for CD4 decline in AIDS in the presence of homeostasis: a worst-case dynamic analysis.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;17(3):245-52.
1997: MR Betts; JF Krowka; C Santamaria; K Balsamo; F Gao; G Mulundu; C Luo; N N'Gandu; Haynes W Sheppard; B H Hahn; Susan Allen; Jeffrey Frelinger
Cross-clade human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte responses in HIV-infected Zambians.
Journal of virology 1997;71(11):8908-11.
1997: Nelson L Michael; Leslie G Louie; A L Rohrbaugh; K A Schultz; Debora Elizabeth Sites (Dayhoff); C E Wang; Haynes W Sheppard
The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression.
Nature medicine 1997;3(10):1160-2.
1997: JF Krowka; M L Gesner; MS Ascher; Haynes W Sheppard
Lack of associations of chemotactic cytokines with viral burden, disease progression, or lymphocyte subsets in HIV-infected individuals.
Clinical immunology and immunopathology 1997;85(1):21-7.
1997: Nelson L Michael; Leslie G Louie; Haynes W Sheppard
CCR5-delta 32 gene deletion in HIV-1 infected patients.
Lancet 1997;350(9079):741-2.
1997: Nelson L Michael; G Chang; Leslie G Louie; John R Mascola; D Dondero; Deborah L Birx; Haynes W Sheppard
The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression.
Nature medicine 1997;3(3):338-40.
1997: JF Krowka; Haynes W Sheppard; MS Ascher
Immunotherapy for HIV.
Lancet 1997;349(9049):434.
1996: JF Krowka; B Cuevas; D C Maron; K S Steimer; MS Ascher; Haynes W Sheppard
Expression of CD69 after in vitro stimulation: a rapid method for quantitating impaired lymphocyte responses in HIV-infected individuals.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;11(1):95-104.
1995: Nelson L Michael; G Chang; L A d'Arcy; C J Tseng; Deborah L Birx; Haynes W Sheppard
Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression.
Journal of virology 1995;69(11):6758-69.
1995: MS Ascher; Haynes W Sheppard; R W Anderson; JF Krowka; H J Bremermann
HIV results in the frame. Paradox remains.
Nature 1995;375(6528):196; author reply 198.
1995: MS Ascher; Haynes W Sheppard; JF Krowka; H J Bremermann
AIDS as immune system activation. Key questions that remain.
Advances in experimental medicine and biology 1995;374():203-10.
1994: Dennis H Osmond; K Page; J Wiley; K Garrett; Haynes W Sheppard; Andrew R Moss; L Schrager; W Winkelstein
HIV infection in homosexual and bisexual men 18 to 29 years of age: the San Francisco Young Men's Health Study.
American journal of public health 1994;84(12):1933-7.
1994: T H Lee; Haynes W Sheppard; M Reis; D Dondero; Dennis H Osmond; M P Busch
Circulating HIV-1-infected cell burden from seroconversion to AIDS: importance of postseroconversion viral load on disease course.
Journal of acquired immune deficiency syndromes 1994;7(4):381-8.
1994: T Wrin; L Crawford; L Sawyer; P Weber; Haynes W Sheppard; Carl Hanson
Neutralizing antibody responses to autologous and heterologous isolates of human immunodeficiency virus.
Journal of acquired immune deficiency syndromes 1994;7(3):211-9.
1994: Haynes W Sheppard; S H Bridges; B J Mathieson; MC Walker; Kent J Weinhold
Conference on advances in AIDS vaccine development--1993. Summary: correlates of HIV Immunity Working Group.
AIDS research and human retroviruses 1994;10 Suppl 2():S171-6.
1993: Haynes W Sheppard; M P Busch; P H Louie; R Madej; G C Rodgers
HIV-1 PCR and isolation in seroconverting and seronegative homosexual men: absence of long-term immunosilent infection.
Journal of acquired immune deficiency syndromes 1993;6(12):1339-46.
1993: Haynes W Sheppard; W Lang; MS Ascher; Eric Vittinghoff; W Winkelstein
The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels.
AIDS (London, England) 1993;7(9):1159-66.
1993: Haynes W Sheppard; MS Ascher; JF Krowka
Viral burden and HIV disease.
Nature 1993;364(6435):291-2.
1993: MS Ascher; Haynes W Sheppard; W Winkelstein; Eric Vittinghoff
Aetiology of AIDS.
Lancet 1993;341(8854):1223.
1993: MS Ascher; Haynes W Sheppard; W Winkelstein; Eric Vittinghoff
Does drug use cause AIDS?
Nature 1993;362(6416):103-4.
1993: Haynes W Sheppard; MS Ascher; W Winkelstein; Eric Vittinghoff; Dennis H Osmond; Andrew R Moss; Stephen Shiboski
Use of T lymphocyte subset analysis in the case definition for AIDS.
Journal of acquired immune deficiency syndromes 1993;6(3):287-94.
1993: Dennis H Osmond; Nancy S Padian; Haynes W Sheppard; S Glass; Stephen Shiboski; Arthur Reingold
Risk factors for hepatitis C virus seropositivity in heterosexual couples.
JAMA : the journal of the American Medical Association 1993;269(3):361-5.
1993: Dennis H Osmond; E Charlebois; Haynes W Sheppard; K Page; W Winkelstein; Andrew R Moss; Arthur Reingold
Comparison of risk factors for hepatitis C and hepatitis B virus infection in homosexual men.
The Journal of infectious diseases 1993;167(1):66-71.
1992: Haynes W Sheppard; MS Ascher
The relationship between AIDS and immunologic tolerance.
Journal of acquired immune deficiency syndromes 1992;5(2):143-7.
1991: L Z Pan; Haynes W Sheppard; W Winkelstein; Jay A Levy
Lack of detection of human immunodeficiency virus in persistently seronegative homosexual men with high or medium risks for infection.
The Journal of infectious diseases 1991;164(5):962-4.
1991: Haynes W Sheppard; W Winkelstein; Dennis H Osmond; Andrew R Moss
Effect of new AIDS case definition on numbers of cases among homosexual and bisexual men in San Francisco.
JAMA : the journal of the American Medical Association 1991;266(16):2221.
1991: B McRae; J A Lange; MS Ascher; F de Wolf; Haynes W Sheppard; J Goudsmit; J P Allain
Immune response to HIV p24 core protein during the early phases of human immunodeficiency virus infection.
AIDS research and human retroviruses 1991;7(8):637-43.
1991: Miroslaw K Gorny; J Y Xu; V Gianakakos; S Karwowska; Constance Williams; Haynes W Sheppard; Carl Hanson; Susan Zolla-Pazner
Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3238-42.
1991: Haynes W Sheppard; MS Ascher; M P Busch; P R Sohmer; M Stanley; M C Luce; J A Chimera; R Madej; G C Rodgers; C Lynch
A multicenter proficiency trial of gene amplification (PCR) for the detection of HIV-1.
Journal of acquired immune deficiency syndromes 1991;4(3):277-83.
1991: Haynes W Sheppard; D Dondero; J Arnon; W Winkelstein
An evaluation of the polymerase chain reaction in HIV-1 seronegative men.
Journal of acquired immune deficiency syndromes 1991;4(8):819-23.
1991: Haynes W Sheppard; MS Ascher; B McRae; R E Anderson; W Lang; J P Allain
The initial immune response to HIV and immune system activation determine the outcome of HIV disease.
Journal of acquired immune deficiency syndromes 1991;4(7):704-12.
1990: Carl Hanson; LK Crawford-Miksza; Haynes W Sheppard
Application of a rapid microplaque assay for determination of human immunodeficiency virus neutralizing antibody titers.
Journal of clinical microbiology 1990;28(9):2030-4.
1990: W Winkelstein; R A Royce; Haynes W Sheppard
Median incubation time for human immunodeficiency virus (HIV)
Annals of internal medicine 1990;112(10):797-8.
1990: MS Ascher; Haynes W Sheppard
AIDS as immune system activation. II. The panergic imnesia hypothesis.
Journal of acquired immune deficiency syndromes 1990;3(2):177-91.