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Arjan Blokland

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Inge Klinkenberg; Wim J Riedel; Arjan Blokland; Anke Sambeth
Cholinergic modulation of auditory processing, sensory gating and novelty detection in human participants.
Olga A H Reneerkens; Kris Rutten; Harry W M Steinbusch; Arjan Blokland; Eva Bollen; Thorsten Hage; Jos Prickaerts
Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801.
O A H Reneerkens; Anke Sambeth; H W M Steinbusch; Marlies A van Duinen; Arjan Blokland; Jos Prickaerts
The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans.

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All Publications

2013: Inge Klinkenberg; Wim J Riedel; Arjan Blokland; Anke Sambeth
Cholinergic modulation of auditory processing, sensory gating and novelty detection in human participants.
Psychopharmacology 2013;225(4):903-21.
2013: Olga A H Reneerkens; Kris Rutten; Harry W M Steinbusch; Arjan Blokland; Eva Bollen; Thorsten Hage; Jos Prickaerts
Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801.
Behavioural brain research 2013;236(1):16-22.
2013: O A H Reneerkens; Anke Sambeth; H W M Steinbusch; Marlies A van Duinen; Arjan Blokland; Jos Prickaerts
The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans.
Psychopharmacology 2013;225(2):303-12.
2013: Sarah Hescham; Ali Jahanshahi; Lee Wei Lim; Jos Prickaerts; Harry W M Steinbusch; Arjan Blokland; Yasin Temel
Deep brain stimulation of the forniceal area enhances memory functions in experimental dementia: the role of stimulation parameters.
Brain stimulation 2013;6(1):72-7.
2012: Inge Klinkenberg; Wim Riedel; Arjan Blokland; Anke Sambeth
Human electrophysiological correlates of learned irrelevance: effects of the muscarinic M1 antagonist biperiden.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(10):1375-85.
2012: Yasin Temel; Arjan Blokland; Lee Wei Lim
Deactivation of the parvalbumin-positive interneurons in the hippocampus after fear-like behaviour following electrical stimulation of the dorsolateral periaqueductal gray of rats.
Behavioural brain research 2012;233(2):322-5.
2012: Sven Akkerman; Arjan Blokland; Eva Bollen; Hieronymus J M Gijselaers; Cindy K J Lieben; Olga Reneerkens; Harry W M Steinbusch; Nick P van Goethem; Jos Prickaerts
Object recognition testing: methodological considerations on exploration and discrimination measures.
Behavioural brain research 2012;232(2):335-47.
2012: Nick P van Goethem; José van't Klooster; Kris Rutten; Harry W M Steinbusch; Franz Josef van der Staay; Sven Akkerman; Arjan Blokland; Linda A W Jans; Jos Prickaerts
Object recognition testing: rodent species, strains, housing conditions, and estrous cycle.
Behavioural brain research 2012;232(2):323-34.
2012: Sven Akkerman; Jos Prickaerts; Harry W M Steinbusch; Arjan Blokland
Object recognition testing: statistical considerations.
Behavioural brain research 2012;232(2):317-22.
2012: Olga A H Reneerkens; Kris Rutten; Christopher L Shaffer; Harry W M Steinbusch; Sven Akkerman; Arjan Blokland; Frank S Menniti; Jos Prickaerts
Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanisms.
Neurobiology of learning and memory 2012;97(4):370-9.
2012: Arjan Blokland; Sarah Keuter; Alexandra Krugliak; Anthony Napoletano; Emily Nguyen; Theodor Schmidt; Sanne Ten Oever; Michael van Draanen; Dennis van Gorp; Inge Klinkenberg
The use of a test battery assessing affective behavior in rats: order effects.
Behavioural brain research 2012;228(1):16-21.
2012: Bart Aben; Sven Stapert; Arjan Blokland
About the Distinction between Working Memory and Short-Term Memory.
Frontiers in psychology 2012;3():301.
2011: Inge Klinkenberg; Anke Sambeth; Arjan Blokland
Acetylcholine and attention.
Behavioural brain research 2011;221(2):430-42.
2011: Kris Rutten; Tanya L Wallace; Melissa Works; Jos Prickaerts; Arjan Blokland; Thomas J Novak; Luca Santarelli; Dinah L Misner
Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B-/-) mice.
Neuropharmacology 2011;61(1-2):138-47.
2011: Tim Vanmierlo; Arjan Blokland; Vincent W Bloks; Jos Dederen; Amanda Kiliaan; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Kris Rutten; Eric J G Sijbrands; Harry Steinbusch; Leonie C van Vark-van der Zee; Monique Mulder
Liver X receptor activation restores memory in aged AD mice without reducing amyloid.
Neurobiology of aging 2011;32(7):1262-72.
2011: Tim Vanmierlo; Arjan Blokland; Vincent Bloks; Silvia Friedrichs; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Frans C Ramaekers; Kris Rutten; Eric Sijbrands; Harry Steinbusch; Leonie C van Vark-van der Zee; Monique Mulder
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
Plant foods for human nutrition (Dordrecht, Netherlands) 2011;66(2):149-56.
2011: Inge Klinkenberg; Arjan Blokland
A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment.
Psychopharmacology 2011;215(3):549-66.
2011: Lee Wei Lim; Arjan Blokland; Marlies van Duinen; Veerle Visser-Vandewalle; Sonny Tan; Rinske Vlamings; Mark Janssen; Ali Jahanshahi; Mujzgan Aziz-Mohammadi; Harry W M Steinbusch; Koen Schruers; Yasin Temel
Increased plasma corticosterone levels after periaqueductal gray stimulation-induced escape reaction or panic attacks in rats.
Behavioural brain research 2011;218(2):301-7.
2011: Jimmy F P Berbée; Arjan Blokland; Thomas Gautier; M'hamed Hadfoune; Paula J Jansen; Folkert Kuipers; Dieter Lütjohann; Jos Prickaerts; Frans C S Ramaekers; Patrick C N Rensen; Eric Sijbrands; Tim Vanmierlo; Karlygash Abildayeva; Monique Mulder
Apolipoprotein CI knock-out mice display impaired memory functions.
Journal of Alzheimer's disease : JAD 2011;23(4):737-47.
2010: Lee Wei Lim; Arjan Blokland; Sonny Tan; Rinske Vlamings; thibaut sesia; Mujzgan Aziz-Mohammadi; Veerle Visser-Vandewalle; Harry W M Steinbusch; Koen Schruers; Yasin Temel
Attenuation of fear-like response by escitalopram treatment after electrical stimulation of the midbrain dorsolateral periaqueductal gray.
Experimental neurology 2010;226(2):293-300.
2010: thibaut sesia; Vincent Bulthuis; Sonny Tan; Lee Wei Lim; Rinske Vlamings; Arjan Blokland; Harry W M Steinbusch; Trevor Sharp; Veerle Visser-Vandewalle; Yasin Temel
Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin.
Experimental neurology 2010;225(2):302-9.
2010: Inge Klinkenberg; Arjan Blokland
The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies.
Neuroscience and biobehavioral reviews 2010;34(8):1307-50.
2010: Eva L van Donkelaar; Paul A T Kelly; Neil Dawson; Arjan Blokland; Jos Prickaerts; Harry W M Steinbusch; Linda Ferrington
Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats.
Journal of neuroscience research 2010;88(7):1557-68.
2010: L A W Jans; G A H Korte-Bouws; S M Korte; Arjan Blokland
The effects of acute tryptophan depletion on affective behaviour and cognition in Brown Norway and Sprague Dawley rats.
Journal of psychopharmacology (Oxford, England) 2010;24(4):605-14.
2010: Eva L van Donkelaar; Arjan Blokland; Cindy K J Lieben; Gunter Kenis; Linda Ferrington; Paul A T Kelly; Harry W M Steinbusch; Jos Prickaerts
Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes.
Neurochemistry international 2010;56(1):21-34.
2009: Eva L van Donkelaar; Daniël L A van den Hove; Arjan Blokland; Harry W M Steinbusch; Jos Prickaerts
Stress-mediated decreases in brain-derived neurotrophic factor as potential confounding factor for acute tryptophan depletion-induced neurochemical effects.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(11):812-21.
2009: E L van Donkelaar; L Ferrington; Arjan Blokland; H W M Steinbusch; Jos Prickaerts; P A T Kelly
Acute tryptophan depletion in rats alters the relationship between cerebral blood flow and glucose metabolism independent of central serotonin.
Neuroscience 2009;163(2):683-94.
2009: Lee Wei Lim; Yasin Temel; Veerle Visser-Vandewalle; Arjan Blokland; Harry W M Steinbusch
Fos immunoreactivity in the rat forebrain induced by electrical stimulation of the dorsolateral periaqueductal gray matter.
Journal of chemical neuroanatomy 2009;38(2):83-96.
2009: Kris Rutten; Eva L Van Donkelaar; Linda Ferrington; Arjan Blokland; Eva Bollen; Harry Wm Steinbusch; Paul At Kelly; Jos Hhj Prickaerts
Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(8):1914-25.
2009: L A W Jans; C K J Lieben; L T Smits; Arjan Blokland
Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats.
Amino acids 2009;37(2):349-57.
2009: Anke Sambeth; Martijn Meeter; Arjan Blokland
Hippocampal theta frequency and novelty.
Hippocampus 2009;19(4):407-8; author reply 409-10.
2009: Evi M P Lemmens; Brenda Aendekerk; Olaf E M G Schijns; Arjan Blokland; E A M Beuls; Govert Hoogland
Long-term behavioral outcome after early-life hyperthermia-induced seizures.
Epilepsy & behavior : E&B 2009;14(2):309-15.
2009: Olga A H Reneerkens; Kris Rutten; Harry W M Steinbusch; Arjan Blokland; Jos Prickaerts
Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.
Psychopharmacology 2009;202(1-3):419-43.
2009: Anke Sambeth; Wim J Riedel; D E Tillie; Arjan Blokland; A Postma; Jeroen A J Schmitt
Memory impairments in humans after acute tryptophan depletion using a novel gelatin-based protein drink.
Journal of psychopharmacology (Oxford, England) 2009;23(1):56-64.
2008: Eva L van Donkelaar; Kris Rutten; Arjan Blokland; Sven Akkerman; Harry W M Steinbusch; Jos Prickaerts
Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion.
European journal of pharmacology 2008;600(1-3):98-104.
2008: Lee Wei Lim; Arjan Blokland; Veerle Visser-Vandewalle; Rinske Vlamings; thibaut sesia; Harry W M Steinbusch; Koen Schruers; Eric Griez; Yasin Temel
High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour.
Behavioural brain research 2008;193(2):197-203.
2008: thibaut sesia; Yasin Temel; Lee Wei Lim; Arjan Blokland; Harry W M Steinbusch; Veerle Visser-Vandewalle
Deep brain stimulation of the nucleus accumbens core and shell: opposite effects on impulsive action.
Experimental neurology 2008;214(1):135-9.
2008: Linda A W Jans; Arjan Blokland
Influence of chronic mild stress on the behavioural effects of acute tryptophan depletion induced by a gelatin-based mixture.
Behavioural pharmacology 2008;19(7):706-15.
2008: F Josef van der Staay; Kris Rutten; Lars Bärfacker; Jean Devry; Christina Erb; Heike Heckroth; Dagmar Karthaus; Adrian Tersteegen; Marja van Kampen; Arjan Blokland; Jos Prickaerts; Klaus G Reymann; Ulrich H Schröder; Martin Hendrix
The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents.
Neuropharmacology 2008;55(5):908-18.
2008: Kris Rutten; Jos Prickaerts; G Schaenzle; H Rosenbrock; Arjan Blokland
Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats.
Neurobiology of learning and memory 2008;90(3):569-75.
2008: Arjan Blokland; Frank Boess
Use of behavioural and long-term potentiation models in the development of memory-improving drugs.
Expert opinion on drug discovery 2008;3(9):1067-80.
2008: Kris Rutten; Dinah L Misner; Melissa Works; Arjan Blokland; Thomas J Novak; Luca Santarelli; Tanya L Wallace
Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D) mice.
The European journal of neuroscience 2008;28(3):625-32.
2008: Lee Wei Lim; Yasin Temel; thibaut sesia; Rinske Vlamings; Veerle Visser-Vandewalle; Harry W M Steinbusch; Arjan Blokland
Buspirone induced acute and chronic changes of neural activation in the periaqueductal gray of rats.
Neuroscience 2008;155(1):164-73.
2008: Kris Rutten; O A H Reneerkens; H Hamers; Ayhan Sik; I S McGregor; Jos Prickaerts; Arjan Blokland
Automated scoring of novel object recognition in rats.
Journal of neuroscience methods 2008;171(1):72-7.
2008: Karlygash Abildayeva; Jimmy F P Berbée; Arjan Blokland; Paula J Jansen; Frans J Hoek; Onno Meijer; Dieter Lütjohann; Thomas Gautier; Thierry Pillot; Jan de Vente; Louis M Havekes; Frans C S Ramaekers; Folkert Kuipers; Patrick C N Rensen; Monique Mulder
Human apolipoprotein C-I expression in mice impairs learning and memory functions.
Journal of lipid research 2008;49(4):856-69.
2008: Kris Rutten; J L Basile; Jos Prickaerts; Arjan Blokland; J A Vivian
Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.
Psychopharmacology 2008;196(4):643-8.
2008: Lee Wei Lim; Yasin Temel; Veerle Visser-Vandewalle; Harry Steinbusch; Koen Schruers; Rob Hameleers; Gabriel Esquivel; Eric Griez; Arjan Blokland
Effect of buspirone on the behavioral regulation of rats in low versus high anxiety conditions.
Arzneimittel-Forschung 2008;58(6):269-76.
2007: Rob Hameleers; Arjan Blokland; Harry W M Steinbusch; Veerle Visser-Vandewalle; Yasin Temel
Hypomobility after DOI administration can be reversed by subthalamic nucleus deep brain stimulation.
Behavioural brain research 2007;185(1):65-7.
2007: Geoffrey Van der Plasse; Dorie T J Meerkerk; Cindy K J Lieben; Arjan Blokland; Matthijs G P Feenstra
Lack of evidence for reduced prefrontal cortical serotonin and dopamine efflux after acute tryptophan depletion.
Psychopharmacology 2007;195(3):377-85.
2007: Monique Mulder; Guido C Koopmans; Guido Wassink; Ghais Al Mansouri; Marie-Lune Simard; Louis M Havekes; Jos Prickaerts; Arjan Blokland
LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus.
Neuroscience research 2007;59(3):251-6.
2007: Anke Sambeth; Wim J Riedel; Laura Th Smits; Arjan Blokland
Cholinergic drugs affect novel object recognition in rats: relation with hippocampal EEG?
European journal of pharmacology 2007;572(2-3):151-9.
2007: Yasin Temel; Laura J Boothman; Arjan Blokland; Peter J Magill; Harry W M Steinbusch; Veerle Visser-Vandewalle; Trevor Sharp
Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17087-92.
2007: L A W Jans; Cindy K J Lieben; Arjan Blokland
Influence of sex and estrous cycle on the effects of acute tryptophan depletion induced by a gelatin-based mixture in adult Wistar rats.
Neuroscience 2007;147(2):304-17.
2007: Kris Rutten; Cindy K J Lieben; Luc Smits; Arjan Blokland
The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat.
Psychopharmacology 2007;192(2):275-82.
2007: L A W Jans; Wim J Riedel; C Rob Markus; Arjan Blokland
Serotonergic vulnerability and depression: assumptions, experimental evidence and implications.
Molecular psychiatry 2007;12(6):522-43.
2007: Erik I Hoff; Robert J van Oostenbrugge; Marjolein Liedenbaum; Harry W M Steinbusch; Arjan Blokland
Effects of right-hemisphere cortical infarction and muscarinic acetylcholine receptor blockade on spatial visual attention performance in rats.
Behavioural brain research 2007;178(1):62-9.
2007: Kris Rutten; Jos Prickaerts; Martin Hendrix; F Josef van der Staay; Ayhan Sik; Arjan Blokland
Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors.
European journal of pharmacology 2007;558(1-3):107-12.
2007: rudy schreiber; Jef Vivian; Linda Hedley; Krystine Szczepanski; Rob L Secchi; Marcus Zuzow; Susanne van Laarhoven; Jean-Luc Moreau; James R Martin; Ayhan Sik; Arjan Blokland
Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2007;17(4):277-88.
2007: Anke Sambeth; Arjan Blokland; Catherine J Harmer; T O C Kilkens; Pradeep Nathan; Richard John Porter; Jeroen A J Schmitt; Bart Scholtissen; Sjacko Sobczak; Allan H Young; Wim J Riedel
Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studies.
Neuroscience and biobehavioral reviews 2007;31(4):516-29.
2006: Yasin Temel; Veerle Visser-Vandewalle; Suleyman Kaplan; Ramazan Kozan; Marc A R C Daemen; Arjan Blokland; Christoph Schmitz; Harry W M Steinbusch
Protection of nigral cell death by bilateral subthalamic nucleus stimulation.
Brain research 2006;1120(1):100-5.
2006: Yasin Temel; Chunyan Cao; Rinske Vlamings; Arjan Blokland; Hatice Ozen; Harry W M Steinbusch; Kimmo A Michelsen; Stephan von Hörsten; Christoph Schmitz; Veerle Visser-Vandewalle
Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington's disease.
Neuroscience letters 2006;406(1-2):138-41.
2006: Arjan Blokland; Kris Rutten; Jos Prickaerts
Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task.
Behavioural brain research 2006;171(2):216-24.
2006: Chunyan Cao; Yasin Temel; Arjan Blokland; Hatice Ozen; Harry W M Steinbusch; Rinske Vlamings; Huu-Phuc Nguyen; Stephan von Hörsten; Christoph Schmitz; Veerle Visser-Vandewalle
Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel.
Behavioural brain research 2006;170(2):257-61.
2006: Orsolya Kántor; Yasin Temel; Carsten Holzmann; Kerstin Raber; Huu-Phuc Nguyen; Chunyan Cao; Hatice Ozen Türkoglu; Bart P F Rutten; Veerle Visser-Vandewalle; Harry W M Steinbusch; Arjan Blokland; Hubert Korr; Olaf Riess; Stephan von Hörsten; Christoph Schmitz
Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats.
Neurobiology of disease 2006;22(3):538-47.
2006: Cindy K J Lieben; Harry W M Steinbusch; Arjan Blokland
5,7-DHT lesion of the dorsal raphe nuclei impairs object recognition but not affective behavior and corticosterone response to stressor in the rat.
Behavioural brain research 2006;168(2):197-207.
2006: Sonny K H Tan; Yasin Temel; Arjan Blokland; Harry W M Steinbusch; Veerle Visser-Vandewalle
The subthalamic nucleus: From response selection to execution.
Journal of chemical neuroanatomy 2006;31(3):155-61.
2006: Yasin Temel; Arjan Blokland; Linda Ackermans; Paul Boon; Vivianne H J M van Kranen-Mastenbroek; E A M Beuls; Geert H Spincemaille; Veerle Visser-Vandewalle
Differential effects of subthalamic nucleus stimulation in advanced Parkinson disease on reaction time performance.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2006;169(3):389-99.
2006: Kris Rutten; Jos Prickaerts; Arjan Blokland
Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action.
Neurobiology of learning and memory 2006;85(2):132-8.
2006: Bart Scholtissen; Ronald Deumens; Albert F G Leentjens; Christoph Schmitz; Arjan Blokland; Harry W M Steinbusch; Jos Prickaerts
Functional investigations into the role of dopamine and serotonin in partial bilateral striatal 6-hydroxydopamine lesioned rats.
Pharmacology, biochemistry, and behavior 2006;83(2):175-85.
2006: Erik I Hoff; Arjan Blokland; Kris Rutten; Harry W M Steinbusch; Robert J van Oostenbrugge
Dissociable effects in reaction time performance after unilateral cerebral infarction: a comparison between the left and right frontal cortices in rats.
Brain research 2006;1069(1):182-9.
2006: Arjan Blokland; R Schreiber; Jos Prickaerts
Improving memory: a role for phosphodiesterases.
Current pharmaceutical design 2006;12(20):2511-23.
2005: Cindy K J Lieben; Arjan Blokland; Ayhan Sik; Eric Sung; Petra van Nieuwenhuijzen; Rudy Schreiber
The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(12):2169-79.
2005: Kris Rutten; J De Vente; Ayhan Sik; M Markerink-Van Ittersum; Jos Prickaerts; Arjan Blokland
The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP levels in hippocampal slices.
Behavioural brain research 2005;164(1):11-6.
2005: Yasin Temel; Arjan Blokland; Harry W M Steinbusch; Veerle Visser-Vandewalle
The functional role of the subthalamic nucleus in cognitive and limbic circuits.
Progress in neurobiology 2005;76(6):393-413.
2005: Yasin Temel; Veerle Visser-Vandewalle; Brenda Aendekerk; Bart P F Rutten; Sonny Tan; Bart Scholtissen; Christoph Schmitz; Arjan Blokland; Harry W M Steinbusch
Acute and separate modulation of motor and cognitive performance in parkinsonian rats by bilateral stimulation of the subthalamic nucleus.
Experimental neurology 2005;193(1):43-52.
2005: Arjan Blokland; Ayhan Sik; Cindy K J Lieben
Evaluation of DOI, 8-OH-DPAT, eticlopride and amphetamine on impulsive responding in a reaction time task in rats.
Behavioural pharmacology 2005;16(2):93-100.
2005: Jos Prickaerts; Ayhan Sik; Franz Josef van der Staay; Jan de Vente; Arjan Blokland
Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation.
Psychopharmacology 2005;177(4):381-90.
2004: Frank G Boess; Martin Hendrix; Franz-Josef van der Staay; Christina Erb; Rudy Schreiber; Wilma van Staveren; Jan de Vente; Jos Prickaerts; Arjan Blokland; Gerhard Koenig
Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance.
Neuropharmacology 2004;47(7):1081-92.
2004: Jos Prickaerts; Ayhan Sik; Wilma C G van Staveren; Guido C Koopmans; Harry W M Steinbusch; Franz Josef van der Staay; Jan de Vente; Arjan Blokland
Phosphodiesterase type 5 inhibition improves early memory consolidation of object information.
Neurochemistry international 2004;45(6):915-28.
2004: Arjan Blokland; Elke Geraerts; Marin Been
A detailed analysis of rats' spatial memory in a probe trial of a Morris task.
Behavioural brain research 2004;154(1):71-5.
2004: Arjan Blokland; Ayhan Sik; F Josef van der Staay
Delayed non-matching to position performance in aged hybrid Fischer 344 x brown Norway rats: a longitudinal study.
Brain research bulletin 2004;64(1):39-46.
2004: Monique Mulder; Paula J Jansen; Ben J A Janssen; Wilma D J Van De Berg; Hans van der Boom; Louis M Havekes; Ron de Kloet; Frans C S Ramaekers; Arjan Blokland
Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus.
Neurobiology of disease 2004;16(1):212-9.
2004: Lieve Desbonnet; Yasin Temel; Veerle Visser-Vandewalle; Arjan Blokland; Veronique Hornikx; Harry W M Steinbusch
Premature responding following bilateral stimulation of the rat subthalamic nucleus is amplitude and frequency dependent.
Brain research 2004;1008(2):198-204.
2004: Cindy K J Lieben; Kim van Oorsouw; Nicolaas E P Deutz; Arjan Blokland
Acute tryptophan depletion induced by a gelatin-based mixture impairs object memory but not affective behavior and spatial learning in the rat.
Behavioural brain research 2004;151(1-2):53-64.
2004: Jos Prickaerts; Guido C Koopmans; Arjan Blokland; Arjan Scheepens
Learning and adult neurogenesis: survival with or without proliferation?
Neurobiology of learning and memory 2004;81(1):1-11.
2004: Cindy K J Lieben; Arjan Blokland; B Westerink; Nicolaas E P Deutz
Acute tryptophan and serotonin depletion using an optimized tryptophan-free protein-carbohydrate mixture in the adult rat.
Neurochemistry international 2004;44(1):9-16.
2003: Ayhan Sik; Petra van Nieuwehuyzen; Jos Prickaerts; Arjan Blokland
Performance of different mouse strains in an object recognition task.
Behavioural brain research 2003;147(1-2):49-54.
2003: Guido C Koopmans; Arjan Blokland; Petra van Nieuwenhuijzen; Jos Prickaerts
Assessment of spatial learning abilities of mice in a new circular maze.
Physiology & behavior 2003;79(4-5):683-93.
2003: Wilma D J Van De Berg; Martijn Kwaijtaal; A J A De Louw; N P A Lissone; Christoph Schmitz; R L M Faull; Arjan Blokland; carlos blanco; Harry W M Steinbusch
Impact of perinatal asphyxia on the GABAergic and locomotor system.
Neuroscience 2003;117(1):83-96.
2002: Ronald Deumens; Arjan Blokland; Jos Prickaerts
Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway.
Experimental neurology 2002;175(2):303-17.
2002: Arjan Blokland; Cindy K J Lieben; Nicolaas E P Deutz
Anxiogenic and depressive-like effects, but no cognitive deficits, after repeated moderate tryptophan depletion in the rat.
Journal of psychopharmacology (Oxford, England) 2002;16(1):39-49.
2002: Jos Prickaerts; Jan de Vente; W M M Honig; Harry W M Steinbusch; Arjan Blokland
cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation.
European journal of pharmacology 2002;436(1-2):83-7.
2002: Jos Prickaerts; Wilma C G van Staveren; Ayhan Sik; Marjanne Markerink-van Ittersum; U Niewöhner; F J van der Staay; Arjan Blokland; Jan de Vente
Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat.
Neuroscience 2002;113(2):351-61.
2001: Arjan Blokland; W M M Honig; J Jolles
Long-term consequences of repeated pentobarbital anaesthesia on choice reaction time performance in ageing rats.
British journal of anaesthesia 2001;87(5):781-3.
2001: Arjan Blokland; Bart Scholtissen; Annemiek Vermeeren; Johannes G Ramaekers
Dissociable effects of histamine H1 antagonists on reaction-time performance in rats.
Pharmacology, biochemistry, and behavior 2001;70(2-3):427-36.
2001: Monique Mulder; Arjan Blokland; D J van den Berg; H Schulten; Arjen Bakker; D Terwel; W M M Honig; Ron de Kloet; Louis M Havekes; Harry W M Steinbusch; E C de Lange
Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):953-60.
2000: Wilma D J Van De Berg; Arjan Blokland; A Claudio Cuello; Christoph Schmitz; W Vreuls; Harry W M Steinbusch; carlos blanco
Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex-a stereological and behavioral analysis.
Journal of chemical neuroanatomy 2000;20(1):71-82.
2000: M Eijkenboom; Arjan Blokland; F J van der Staay
Modelling cognitive dysfunctions with bilateral injections of ibotenic acid into the rat entorhinal cortex.
Neuroscience 2000;101(1):27-39.
2000: Jos Prickaerts; Jan de Vente; W M M Honig; Harry W M Steinbusch; Arjan Blokland; H W Steinbusch
Nitric oxide synthase does not mediate neurotoxicity after an i.c.v. injection of streptozotocin in the rat.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(7):745-66.
2000: C F Loidl; A W D Gavilanes; E H Van Dijk; W Vreuls; Arjan Blokland; Johan S H Vles; Harry W M Steinbusch; carlos blanco
Effects of hypothermia and gender on survival and behavior after perinatal asphyxia in rats.
Physiology & behavior 2000;68(3):263-9.
1999: F J van der Staay; R J Fanelli; Arjan Blokland; Bernard H Schmidt
Behavioral effects of apamin, a selective inhibitor of the SK(Ca)-channel, in mice and rats.
Neuroscience and biobehavioral reviews 1999;23(8):1087-110.
1999: Arjan Blokland; W M M Honig
Intra-striatal haloperidol and scopolamine injections: effects on choice reaction time performance in rats.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;9(6):523-31.
1999: Arjan Blokland; W M M Honig; F Brouns; J Jolles
Cognition-enhancing properties of subchronic phosphatidylserine (PS) treatment in middle-aged rats: comparison of bovine cortex PS with egg PS and soybean PS.
Nutrition (Burbank, Los Angeles County, Calif.) 1999;15(10):778-83.
1999: Jos Prickaerts; W M M Honig; Bernard H Schmidt; Arjan Blokland
Metrifonate improves working but not reference memory performance in a spatial cone field task.
European journal of pharmacology 1999;380(2-3):61-5.
1999: Jos Prickaerts; T Fahrig; Arjan Blokland
Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an i.c.v. injection of streptozotocin: a correlation analysis.
Behavioural brain research 1999;102(1-2):73-88.
1999: Arjan Blokland; Jan de Vente; Jos Prickaerts; W M M Honig; Marjanne Markerink-van Ittersum; Harry W M Steinbusch
Local inhibition of hippocampal nitric oxide synthase does not impair place learning in the Morris water escape task in rats.
The European journal of neuroscience 1999;11(1):223-32.
1998: Arjan Blokland; Jos Prickaerts; W M M Honig; Jan de Vente
State-dependent impairment in object recognition after hippocampal NOS inhibition.
Neuroreport 1998;9(18):4205-8.
1998: Jos Prickaerts; Arjan Blokland; John Bothmer; W M M Honig; Marjanne Markerink-van Ittersum; J Jolles
Acute effects of acetyl-L-carnitine on sodium cyanide-induced behavioral and biochemical deficits.
Neurochemistry international 1998;33(5):435-43.
1998: Arjan Blokland
Reaction time responding in rats.
Neuroscience and biobehavioral reviews 1998;22(6):847-64.
1998: Arjan Blokland; W M M Honig; Jos Prickaerts
Effects of haloperidol and d-amphetamine on working and reference memory performance in a spatial cone field task.
Behavioural pharmacology 1998;9(5-6):429-36.
1998: Arjan Blokland
Involvement of striatal cholinergic receptors in reaction time and fixed-interval responding in rats.
Brain research bulletin 1998;45(1):21-5.
1996: F J van der Staay; Arjan Blokland
Behavioral differences between outbred Wistar, inbred Fischer 344, brown Norway, and hybrid Fischer 344 x brown Norway rats.
Physiology & behavior 1996;60(1):97-109.
1996: Jos Prickaerts; W Raaijmakers; Arjan Blokland
Effects of myocardial infarction and captopril therapy on anxiety-related behaviors in the rat.
Physiology & behavior 1996;60(1):43-50.
1996: F J van der Staay; Arjan Blokland
Repeated assessment of spatial discrimination performance of aged rats in the Morris water escape task.
Neurobiology of learning and memory 1996;65(1):99-102.
1995: Jos Prickaerts; Arjan Blokland; W M M Honig; F Meng; J Jolles
Spatial discrimination learning and choline acetyltransferase activity in streptozotocin-treated rats: effects of chronic treatment with acetyl-L-carnitine.
Brain research 1995;674(1):142-6.
1993: Arjan Blokland; Jos Prickaerts; W Raaijmakers
Absence of impairments in spatial and temporal discrimination learning in Lewis rats after chronic ethanol consumption.
Pharmacology, biochemistry, and behavior 1993;46(1):27-34.
1993: Arjan Blokland; W Raaijmakers
Age-related changes in correlation between behavioral and biochemical parameters in Lewis rats.
Behavioral and neural biology 1993;60(1):52-61.
1993: Arjan Blokland; J Bothmer; W M M Honig; J Jolles
Behavioural and biochemical effects of acute central metabolic inhibition: effects of acetyl-l-carnitine.
European journal of pharmacology 1993;235(2-3):275-81.
1993: Arjan Blokland; J Jolles
Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin.
Pharmacology, biochemistry, and behavior 1993;44(2):491-4.
1992: Arjan Blokland; Jos Prickaerts; W Raaijmakers
Reduced level of anxiety in adult Lewis rats after chronic ethanol consumption.
Physiology & behavior 1992;51(2):245-8.
1992: Arjan Blokland; W M M Honig; W G Raaijmakers
Effects of intra-hippocampal scopolamine injections in a repeated spatial acquisition task in the rat.
Psychopharmacology 1992;109(3):373-6.
1990: Arjan Blokland; W Raaijmakers; F J van der Staay; J Jolles
Differential effect of acetyl-l-carnitine on open field behavior in young and old rats.
Physiology & behavior 1990;47(4):783-5.
1990: F J van der Staay; B Krechting; Arjan Blokland; W Raaijmakers
The cone field: a spatial discrimination task for the automatic and simultaneous assessment of working and reference memory in rats.
Journal of neuroscience methods 1990;31(1):13-22.