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David Sherman

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TOP 3
Alison R H Narayan; David H Sherman
Chemistry. Re-engineering nature's catalysts.
James D Sunderhaus; Sachiko Tsukamoto; Jennifer M Finefield; Hikaru Kato; Shengying Li; Timothy J McAfoos; David H Sherman; Robert M Williams
Synthesis and bioconversions of notoamide T: a biosynthetic precursor to stephacidin A and notoamide B.
Jennifer Gehret McCarthy; David H Sherman; Peter Wipf; Eli B Eisman; Lena Gerwick; William H Gerwick; Sarang Kulkarni; Janet L Smith
Structural basis of functional group activation by sulfotransferases in complex metabolic pathways.

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All Publications

2013: Alison R H Narayan; David H Sherman
Chemistry. Re-engineering nature's catalysts.
Science (New York, N.Y.) 2013;339(6117):283-4.
2013: James D Sunderhaus; Sachiko Tsukamoto; Jennifer M Finefield; Hikaru Kato; Shengying Li; Timothy J McAfoos; David H Sherman; Robert M Williams
Synthesis and bioconversions of notoamide T: a biosynthetic precursor to stephacidin A and notoamide B.
Organic letters 2013;15(1):22-5.
2012: Jennifer Gehret McCarthy; David H Sherman; Peter Wipf; Eli B Eisman; Lena Gerwick; William H Gerwick; Sarang Kulkarni; Janet L Smith
Structural basis of functional group activation by sulfotransferases in complex metabolic pathways.
ACS chemical biology 2012;7(12):1994-2003.
2012: Chinmay Y Majmudar; Carl J Arevang; Charles L Brooks; Laura C Cesa; Tomasz Cierpicki; Conor H Doss; Jessica K Gagnon; Jonas W Højfeldt; William C Pomerantz; Steven P Rowe; Pamela J Schultz; David H Sherman; Giselle Tamayo; Victor Vásquez; Anna K Mapp
Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.
Angewandte Chemie (International ed. in English) 2012;51(45):11258-62.
2012: Dongju Kim; Ji-Hye Nah; David H Sherman; Hwa Sung Shin; Si-Sun Choi; Eung-Soo Kim
Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412.
Journal of industrial microbiology & biotechnology 2012;39(10):1563-8.
2012: Renju T Jacob; Paul D Kirchhoff; Martha J Larsen; Scott D Larsen; David H Sherman; Richard Neubig
MScreen: an integrated compound management and high-throughput screening data storage and analysis system.
Journal of biomolecular screening 2012;17(8):1080-7.
2012: Yojiro Anzai; Ayaka Domeki; Chie Harada; Kenji Kinoshita; Shengying Li; Ryohei Masuda; Ayami Sakai; David H Sherman; Shu-ichi Tsukada; Fumio Kato
Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin.
Antimicrobial agents and chemotherapy 2012;56(7):3648-56.
2012: Mi-Jin Lee; Shuangjun Lin; David H Sherman; Dekun Kong; Linquan Bai; Zixin Deng; Kyuboem Han; Eung-Soo Kim
Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica.
Applied microbiology and biotechnology 2012;95(1):157-68.
2012: Jennifer M Finefield; Martin Kreitman; David H Sherman; Robert M Williams
Enantiomeric natural products: occurrence and biogenesis.
Angewandte Chemie (International ed. in English) 2012;51(20):4802-36.
2012: Joseph A Chemler; George E Chlipala; Todd W Geders; Christopher M Rath; David L Akey; Tonia J Buchholz; Janet L Smith; David H Sherman
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
Journal of the American Chemical Society 2012;134(17):7359-66.
2012: Jennifer M Finefield; Jens C Frisvad; David H Sherman; Robert M Williams
Fungal origins of the bicyclo[2.2.2]diazaoctane ring system of prenylated indole alkaloids.
Journal of natural products 2012;75(4):812-33.
2012: Jennifer J Gehret; Lena Gerwick; William H Gerwick; Liangcai Gu; David H Sherman; William Clay Brown; Todd W Geders; Janet L Smith
Structure and activity of DmmA, a marine haloalkane dehalogenase.
Protein science : a publication of the Protein Society 2012;21(2):239-48.
2012: Shengying Li; Timothy J McAfoos; James D Sunderhaus; Robert M Williams; Jennifer M Finefield; David H Sherman
Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids.
Journal of the American Chemical Society 2012;134(2):788-91.
2011: Patricia G Cruz; James Inglese; Scott Lovell; Ryan MacArthur; Pamela J Schultz; Min Shen; Douglas S Auld; Kevin P Battaile; Giselle Tamayo; David H Sherman
Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.
Chemistry & biology 2011;18(11):1442-52.
2011: Christopher M Rath; Robert M Williams; Jeremy J Wolff; Fengan Yu; Azad Ahmed; Michael A Christiansen; Meg Dahlgren; Josh Earl; Garth D Ehrlich; Kristina Håkansson; Luisa Hiller; Fen Z Hu; Benjamin Janto; Rachael Kreft; Hye Kyong Kweon; David H Sherman
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743.
ACS chemical biology 2011;6(11):1244-56.
2011: David L Akey; Yojiro Anzai; Steffen M Bernard; Laura A Confer; Fumio Kato; Jamie R Konwerski; Shengying Li; David H Sherman; Janet L Smith
A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
Journal of molecular biology 2011;413(2):438-50.
2011: Shilah A Bonnett; Joseph A Chemler; Kristina Håkansson; Joanna R Joels; Christopher M Rath; Kevin Reynolds; Abdur-Rafay Shareef; David H Sherman
Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS.
Chemistry & biology 2011;18(9):1075-81.
2011: Yousong Ding; Kristina Håkansson; Christopher M Rath; Kyle L Bolduc; David H Sherman
Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.
Journal of the American Chemical Society 2011;133(37):14492-5.
2011: Jennifer M Finefield; Thomas J Greshock; Hikaru Kato; David H Sherman; Sachiko Tsukamoto; Robert M Williams
Biosynthetic studies of the notoamides: isotopic synthesis of stephacidin A and incorporation into notoamide B and sclerotiamide.
Organic letters 2011;13(15):3802-5.
2011: Jennifer M Finefield; David H Sherman; Sachiko Tsukamoto; Robert M Williams
Studies on the biosynthesis of the notoamides: synthesis of an isotopomer of 6-hydroxydeoxybrevianamide E and biosynthetic incorporation into notoamide J.
The Journal of organic chemistry 2011;76(15):5954-8.
2011: Jacob C Carlson; Shamila S Gunatilleke; Shengying Li; Larissa M Podust; Yojiro Anzai; Douglas A Burr; David H Sherman
Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes.
Nature chemistry 2011;3(8):628-33.
2011: Shanteri Singh; Craig A Bingman; Aram Chang; Randal D Goff; Sabine Grüschow; George N Phillips; David H Sherman; Jon S Thorson
Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins 2011;79(7):2181-8.
2011: Liangcai Gu; Eli B Eisman; Somnath Dutta; Titus M Franzmann; Stefan Walter; William H Gerwick; georgios skiniotis; David H Sherman
Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect.
Angewandte Chemie (International ed. in English) 2011;50(12):2795-8.
2011: Jung Yeop Lee; Karla D Passalacqua; Philip C Hanna; David H Sherman
Regulation of petrobactin and bacillibactin biosynthesis in Bacillus anthracis under iron and oxygen variation.
PloS one 2011;6(6):e20777.
2010: Jonathan D Mortison; David H Sherman
Frontiers and opportunities in chemoenzymatic synthesis.
The Journal of organic chemistry 2010;75(21):7041-51.
2010: Tonia J Buchholz; Christopher M Rath; Nicole B Lopanik; Noah P Gardner; Kristina Håkansson; David H Sherman
Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.
Chemistry & biology 2010;17(10):1092-100.
2010: Stephanie D Himpsl; Melanie Pearson; Carl J Arewång; Tyler D Nusca; David H Sherman; harry mobley
Proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in Proteus mirabilis.
Molecular microbiology 2010;78(1):138-57.
2010: Yousong Ding; Jeffrey R de Wet; James Cavalcoli; Shengying Li; Thomas J Greshock; Kenneth A Miller; Jennifer M Finefield; James D Sunderhaus; Timothy J McAfoos; Sachiko Tsukamoto; Robert M Williams; David H Sherman
Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp.
Journal of the American Chemical Society 2010;132(36):12733-40.
2010: Dheeraj Khare; Bo Wang; Liangcai Gu; Jamie Razelun; David H Sherman; William H Gerwick; Kristina Håkansson; Janet L Smith
Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(32):14099-104.
2010: Jamie B Scaglione; David L Akey; Rachel Sullivan; Jeffrey D Kittendorf; Christopher M Rath; Eung-Soo Kim; Janet L Smith; David H Sherman
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.
Angewandte Chemie (International ed. in English) 2010;49(33):5726-30.
2010: Adam C Jones; Emily A Monroe; Eli B Eisman; Lena Gerwick; David H Sherman; William H Gerwick
The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria.
Natural product reports 2010;27(7):1048-65.
2010: Shu-ichi Tsukada; Yojiro Anzai; Shengying Li; Kenji Kinoshita; David H Sherman; Fumio Kato
Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site.
FEMS microbiology letters 2010;304(2):148-56.
2010: Jacob C Carlson; J L Fortman; Yojiro Anzai; Shengying Li; Douglas A Burr; David H Sherman
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.
Chembiochem : a European journal of chemical biology 2010;11(4):564-72.
2010: Paul E Carlson; Shandee D Dixon; Brian K Janes; Katherine A Carr; Tyler D Nusca; Erica C Anderson; Sarra E Keene; David H Sherman; Philip C Hanna
Genetic analysis of petrobactin transport in Bacillus anthracis.
Molecular microbiology 2010;75(4):900-9.
2010: David L Akey; Jamie R Razelun; Jason Tehranisa; David H Sherman; William H Gerwick; Janet L Smith
Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.
Structure (London, England : 1993) 2010;18(1):94-105.
2009: Liangcai Gu; Bo Wang; Amol Kulkarni; Jennifer J Gehret; Kayla R Lloyd; Lena Gerwick; William H Gerwick; Peter Wipf; Kristina Håkansson; Janet L Smith; David H Sherman
Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis.
Journal of the American Chemical Society 2009;131(44):16033-5.
2009: Jonathan D Mortison; Jeffrey D Kittendorf; David H Sherman
Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases.
Journal of the American Chemical Society 2009;131(43):15784-93.
2009: Shengying Li; Mani Chaulagain; Allison R Knauff; Larissa M Podust; John Montgomery; David H Sherman
Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18463-8.
2009: Jacob C Carlson; Shengying Li; Douglas A Burr; David H Sherman
Isolation and characterization of tirandamycins from a marine-derived Streptomyces sp.
Journal of natural products 2009;72(11):2076-9.
2009: Byung-Gyun Kim; Mi-Jin Lee; Jiyoon Seo; Young-Bin Hwang; Mi-Yeon Lee; Kyuboen Han; David H Sherman; Eung-Soo Kim
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.
Journal of industrial microbiology & biotechnology 2009;36(11):1425-34.
2009: David H Sherman
Biochemistry: Enzyme's black box cracked open.
Nature 2009;461(7267):1068-9.
2009: Shin-Hae Park; Si-Sun Choi; Yoon Jung Kim; Yong Keun Chang; David H Sherman; Eung-Soo Kim
Functional expression of SCO7832 stimulates tautomycetin production via pathway-specific regulatory gene overexpression in Streptomyces sp. CK4412.
Journal of industrial microbiology & biotechnology 2009;36(7):993-8.
2009: John Yan; Shuchi Gupta; David H Sherman; Kevin A Reynolds
Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains.
Chembiochem : a European journal of chemical biology 2009;10(9):1537-43.
2009: Liangcai Gu; Bo Wang; Amol Kulkarni; Todd W Geders; Rashel V Grindberg; Lena Gerwick; Kristina Håkansson; Peter Wipf; Janet L Smith; William H Gerwick; David H Sherman
Metamorphic enzyme assembly in polyketide diversification.
Nature 2009;459(7247):731-5.
2009: Shengying Li; Yojiro Anzai; Kenji Kinoshita; Fumio Kato; David H Sherman
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.
Chembiochem : a European journal of chemical biology 2009;10(8):1297-301.
2009: Patrick J Hu; David H Sherman
DANSing with Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7685-6.
2009: Koty Sharp; Karen E Arthur; Liangcai Gu; Cliff Ross; Genelle Harrison; Sarath P Gunasekera; Theresa Meickle; Susan Matthew; Hendrik Luesch; Robert W Thacker; David H Sherman; Valerie J Paul
Phylogenetic and chemical diversity of three chemotypes of bloom-forming lyngbya species (Cyanobacteria: Oscillatoriales) from reefs of southeastern Florida.
Applied and environmental microbiology 2009;75(9):2879-88.
2009: Adam C Jones; Liangcai Gu; Carla Sorrels; David H Sherman; William H Gerwick
New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria.
Current opinion in chemical biology 2009;13(2):216-23.
2009: Jeffrey D Kittendorf; David H Sherman
The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis.
Bioorganic & medicinal chemistry 2009;17(6):2137-46.
2009: Shengying Li; Hugues Ouellet; David H Sherman; Larissa M Podust
Analysis of transient and catalytic desosamine-binding pockets in cytochrome P-450 PikC from Streptomyces venezuelae.
The Journal of biological chemistry 2009;284(9):5723-30.
2009: Stephen Chamberland; Sabine Grüschow; David H Sherman; Robert M Williams
Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C.
Organic letters 2009;11(4):791-4.
2009: Tonia J Buchholz; Todd W Geders; Frank E Bartley; Kevin A Reynolds; Janet L Smith; David H Sherman
Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.
ACS chemical biology 2009;4(1):41-52.
2009: Michael H T Li; Peter M U Ung; James Zajkowski; Sylvie Garneau-Tsodikova; David H Sherman
Automated genome mining for natural products.
BMC bioinformatics 2009;10():185.
2008: Nicole B Lopanik; Jennifer A Shields; Tonia J Buchholz; Christopher M Rath; Joanne Hothersall; Margo G Haygood; Kristina Håkansson; Christopher M Thomas; David H Sherman
In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.
Chemistry & biology 2008;15(11):1175-86.
2008: Yousong Ding; Thomas J Greshock; Kenneth A Miller; David H Sherman; Robert M Williams
Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca.
Organic letters 2008;10(21):4863-6.
2008: Brian F Pfleger; Youngchang Kim; Tyler D Nusca; Natalia Maltseva; Jung Yeop Lee; Christopher M Rath; Jamie B Scaglione; Brian K Janes; Erica C Anderson; Nicholas H Bergman; Philip C Hanna; Andrzej Joachimiak; David H Sherman
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):17133-8.
2008: Yoon-Ah Hur; Si-Sun Choi; David H Sherman; Eung-Soo Kim
Identification of TmcN as a pathway-specific positive regulator of tautomycetin biosynthesis in Streptomyces sp. CK4412.
Microbiology (Reading, England) 2008;154(Pt 10):2912-9.
2008: Yojiro Anzai; Shengying Li; Mani Chaulagain; Kenji Kinoshita; Fumio Kato; John Montgomery; David H Sherman
Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.
Chemistry & biology 2008;15(9):950-9.
2008: Janet L Smith; David H Sherman
Biochemistry. An enzyme assembly line.
Science (New York, N.Y.) 2008;321(5894):1304-5.
2008: Yousong Ding; Sabine Gruschow; Thomas J Greshock; Jennifer M Finefield; David H Sherman; Robert M Williams
Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications.
Journal of natural products 2008;71(9):1574-8.
2008: Yousong Ding; Robert M Williams; David H Sherman
Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca.
The Journal of biological chemistry 2008;283(23):16068-76.
2008: Yousong Ding; Wolfgang H Seufert; Zachary Q Beck; David H Sherman
Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity.
Journal of the American Chemical Society 2008;130(16):5492-8.
2008: Kenneth A Miller; Timothy R Welch; Thomas J Greshock; Yousong Ding; David H Sherman; Robert M Williams
Biomimetic total synthesis of malbrancheamide and malbrancheamide B.
The Journal of organic chemistry 2008;73(8):3116-9.
2008: Jung Yeop Lee; David H Sherman; Byung Kook Hwang
In vitro antimicrobial and in vivo antioomycete activities of the novel antibiotic thiobutacin.
Pest management science 2008;64(2):172-7.
2008: Karthik P Jayapal; Robin J Philp; Yee-Jiun Kok; Miranda G S Yap; David H Sherman; Timothy J Griffin; Wei-Shou Hu
Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor.
PloS one 2008;3(5):e2097.
2008: Wei Lian; Karthik P Jayapal; Salim Charaniya; Sarika Mehra; Frank Glod; YS Kyung; David H Sherman; Wei-Shou Hu
Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).
BMC genomics 2008;9():56.
2007: Todd W Geders; Liangcai Gu; Jonathan C Mowers; Haichuan Liu; William H Gerwick; Kristina Håkansson; David H Sherman; Janet L Smith
Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.
The Journal of biological chemistry 2007;282(49):35954-63.
2007: Liangcai Gu; Todd W Geders; Bo Wang; William H Gerwick; Kristina Håkansson; Janet L Smith; David H Sherman
GNAT-like strategy for polyketide chain initiation.
Science (New York, N.Y.) 2007;318(5852):970-4.
2007: Shengying Li; Larissa M Podust; David H Sherman
Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain.
Journal of the American Chemical Society 2007;129(43):12940-1.
2007: Zachary Q Beck; Douglas A Burr; David H Sherman
Characterization of the beta-methylaspartate-alpha-decarboxylase (CrpG) from the cryptophycin biosynthetic pathway.
Chembiochem : a European journal of chemical biology 2007;8(12):1373-5.
2007: Jeffrey D Kittendorf; Brian J Beck; Tonia J Buchholz; Wolfgang Seufert; David H Sherman
Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.
Chemistry & biology 2007;14(8):944-54.
2007: Namthip Sitachitta; Nicole B Lopanik; Yingqing Mao; David H Sherman
Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase.
The Journal of biological chemistry 2007;282(29):20941-7.
2007: Seok Joon Kwon; Moo-Yeal Lee; Bosung Ku; David H Sherman; Jonathan S Dordick
High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction.
ACS chemical biology 2007;2(6):419-25.
2007: Karla D Passalacqua; Nicholas H Bergman; Jung Yeop Lee; David H Sherman; Philip C Hanna
The global transcriptional responses of Bacillus anthracis Sterne (34F2) and a Delta sodA1 mutant to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress.
Journal of bacteriology 2007;189(11):3996-4013.
2007: Sabine Grüschow; Tonia J Buchholz; Wolfgang Seufert; Jonathan S Dordick; David H Sherman
Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases.
Chembiochem : a European journal of chemical biology 2007;8(8):863-8.
2007: Sabine Grüschow; Leng Chee Chang; Yingqing Mao; David H Sherman
Hydroxyquinone O-methylation in mitomycin biosynthesis.
Journal of the American Chemical Society 2007;129(20):6470-6.
2007: Haichuan Liu; Kristina Håkansson; Jung Yeop Lee; David H Sherman
Collision-activated dissociation, infrared multiphoton dissociation, and electron capture dissociation of the Bacillus anthracis siderophore petrobactin and its metal ion complexes.
Journal of the American Society for Mass Spectrometry 2007;18(5):842-9.
2007: Shengying Li; Sabine Grüschow; Jonathan S Dordick; David H Sherman
Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase.
The Journal of biological chemistry 2007;282(17):12765-72.
2007: Brian F Pfleger; Jung Yeop Lee; Ravindranadh V Somu; Courtney C Aldrich; Philip C Hanna; David H Sherman
Characterization and analysis of early enzymes for petrobactin biosynthesis in Bacillus anthracis.
Biochemistry 2007;46(13):4147-57.
2007: Si-Sun Choi; Yoon-Ah Hur; David H Sherman; Eung-Soo Kim
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.
Microbiology (Reading, England) 2007;153(Pt 4):1095-102.
2007: Jung Yeop Lee; Brian K Janes; Karla D Passalacqua; Brian F Pfleger; Nicholas H Bergman; Haichuan Liu; Kristina Håkansson; Ravindranadh V Somu; Courtney C Aldrich; Stephen Cendrowski; Philip C Hanna; David H Sherman
Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis.
Journal of bacteriology 2007;189(5):1698-710.
2007: Wolfgang Seufert; Zachary Q Beck; David H Sherman
Enzymatic release and macrolactonization of cryptophycins from a safety-catch solid support.
Angewandte Chemie (International ed. in English) 2007;46(48):9298-300.
2007: Karthik P Jayapal; Wei Lian; Frank Glod; David H Sherman; Wei-Shou Hu
Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans.
BMC genomics 2007;8():229.
2007: Sebastian Sudek; Nicole B Lopanik; Laura E Waggoner; Mark Hildebrand; Christine Anderson; Haibin Liu; Amrish Patel; David H Sherman; Margo G Haygood
Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina.
Journal of natural products 2007;70(1):67-74.
2006: Lakshmanan Venkatraman; Christine E Salomon; David H Sherman; Robert A Fecik
Total synthesis of narbonolide and biotransformation to pikromycin.
The Journal of organic chemistry 2006;71(26):9853-6.
2006: Nathan A Magarvey; Zachary Q Beck; Trimurtulu Golakoti; Yousong Ding; Udo Huber; Thomas K Hemscheidt; Dafna Abelson; Richard E Moore; David H Sherman
Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.
ACS chemical biology 2006;1(12):766-79.
2006: Jeffrey D Kittendorf; David H Sherman
Developing tools for engineering hybrid polyketide synthetic pathways.
Current opinion in biotechnology 2006;17(6):597-605.
2006: John W Giraldes; David L Akey; Jeffrey D Kittendorf; David H Sherman; Janet L Smith; Robert A Fecik
Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.
Nature chemical biology 2006;2(10):531-6.
2006: David L Akey; Jeffrey D Kittendorf; John W Giraldes; Robert A Fecik; David H Sherman; Janet L Smith
Structural basis for macrolactonization by the pikromycin thioesterase.
Nature chemical biology 2006;2(10):537-42.
2006: Won Seok Jung; Sang Kil Lee; Jay Sung Joong Hong; Sung Ryeol Park; Soon Jeong Jeong; Ah-Reum Han; Jae Kyung Sohng; Byung-Gee Kim; Cha Yong Choi; David H Sherman; Yeo Joon Yoon
Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae.
Applied microbiology and biotechnology 2006;72(4):763-9.
2006: David H Sherman; Janet L Smith
Clearing the skies over modular polyketide synthases.
ACS chemical biology 2006;1(8):505-9.
2006: David H Sherman; Shengying Li; Liudmila V Yermalitskaya; Youngchang Kim; Jarrod A Smith; Michael R Waterman; Larissa M Podust
The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.
The Journal of biological chemistry 2006;281(36):26289-97.
2006: Liangcai Gu; Junyong Jia; Haichuan Liu; Kristina Håkansson; William H Gerwick; David H Sherman
Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair.
Journal of the American Chemical Society 2006;128(28):9014-5.
2006: Bosung Ku; Junhoe Cha; Aravind Srinivasan; Seok Joon Kwon; Jae-Cheol Jeong; David H Sherman; Jonathan S Dordick
Chip-based polyketide biosynthesis and functionalization.
Biotechnology progress 2006;22(4):1102-7.
2006: Patricia M Flatt; Susan J O'Connell; Kerry L McPhail; Gloria Zeller; Christine L Willis; David H Sherman; William H Gerwick
Characterization of the initial enzymatic steps of barbamide biosynthesis.
Journal of natural products 2006;69(6):938-44.
2006: Sang Kil Lee; Je Won Park; Ji Won Kim; Won Seok Jung; Sung Ryeol Park; Cha Yong Choi; Eung Soo Kim; Beom Seok Kim; Jong Seog Ahn; David H Sherman; Yeo Joon Yoon
Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae.
Journal of natural products 2006;69(5):847-9.
2006: Zachary Q Beck; David H Sherman
Development of an internally quenched fluorogenic substrate for kinetic analysis of thioesterases.
Analytical biochemistry 2006;349(2):309-11.
2006: Sarika Mehra; Wei Lian; Karthik P Jayapal; Salim Charaniya; David H Sherman; Wei-Shou Hu
A framework to analyze multiple time series data: a case study with Streptomyces coelicolor.
Journal of industrial microbiology & biotechnology 2006;33(2):159-72.
2006: Tomoyasu Nishizawa; Sabine Grüschow; Don-Hema E Jayamaha; Chizuko Nishizawa-Harada; David H Sherman
Enzymatic assembly of the bis-indole core of rebeccamycin.
Journal of the American Chemical Society 2006;128(3):724-5.
2005: Zachary Q Beck; Courtney C Aldrich; Nathan A Magarvey; Gunda I Georg; David H Sherman
Chemoenzymatic synthesis of cryptophycin/arenastatin natural products.
Biochemistry 2005;44(41):13457-66.
2005: Lakshmanan Venkatraman; Courtney C Aldrich; David H Sherman; Robert A Fecik
Formal total synthesis of the polyketide macrolactone narbonolide.
The Journal of organic chemistry 2005;70(18):7267-72.
2005: David H Sherman
The Lego-ization of polyketide biosynthesis.
Nature biotechnology 2005;23(9):1083-4.
2005: Courtney C Aldrich; Lakshmanan Venkatraman; David H Sherman; Robert A Fecik
Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide.
Journal of the American Chemical Society 2005;127(25):8910-1.
2005: Courtney C Aldrich; Brian J Beck; Robert A Fecik; David H Sherman
Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates.
Journal of the American Chemical Society 2005;127(23):8441-52.
2005: J L Fortman; David H Sherman
Utilizing the power of microbial genetics to bridge the gap between the promise and the application of marine natural products.
Chembiochem : a European journal of chemical biology 2005;6(6):960-78.
2005: Tomoyasu Nishizawa; Courtney C Aldrich; David H Sherman
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.
Journal of bacteriology 2005;187(6):2084-92.
2005: Jae-Cheol Jeong; Aravind Srinivasan; Sabine Grüschow; Horacio Bach; David H Sherman; Jonathan S Dordick
Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation.
Journal of the American Chemical Society 2005;127(1):64-5.
2004: Nathan A Magarvey; Jessica M Keller; Valerie S Bernan; Martin Dworkin; David H Sherman
Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites.
Applied and environmental microbiology 2004;70(12):7520-9.
2004: Aravind Srinivasan; Horacio Bach; David H Sherman; Jonathan S Dordick
Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform.
Biotechnology and bioengineering 2004;88(4):528-35.
2004: Mark Hildebrand; Laura E Waggoner; Haibin Liu; Sebastian Sudek; Scott Allen; Christine Anderson; David H Sherman; Margo G Haygood
bryA: an unusual modular polyketide synthase gene from the uncultivated bacterial symbiont of the marine bryozoan Bugula neritina.
Chemistry & biology 2004;11(11):1543-52.
2004: Zunxue Chang; Namthip Sitachitta; James V Rossi; Mary Ann Roberts; Patricia M Flatt; Junyong Jia; David H Sherman; William H Gerwick
Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.
Journal of natural products 2004;67(8):1356-67.
2004: Beom Seok Kim; David H Sherman; Kevin A Reynolds
An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases.
Protein engineering, design & selection : PEDS 2004;17(3):277-84.
2004: Christine E Salomon; Nathan A Magarvey; David H Sherman
Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery.
Natural product reports 2004;21(1):105-21.
2004: Larissa M Podust; Horacio Bach; Youngchang Kim; David C Lamb; Miharu Arase; David H Sherman; Steven L Kelly; Michael R Waterman
Comparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathways.
Protein science : a publication of the Protein Society 2004;13(1):255-68.
2003: Brian J Beck; Courtney C Aldrich; Robert A Fecik; Kevin A Reynolds; David H Sherman
Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase.
Journal of the American Chemical Society 2003;125(41):12551-7.
2003: Brian J Beck; Courtney C Aldrich; Robert A Fecik; Kevin A Reynolds; David H Sherman
Iterative chain elongation by a pikromycin monomodular polyketide synthase.
Journal of the American Chemical Society 2003;125(16):4682-3.
2003: Larissa M Podust; Youngchang Kim; Miharu Arase; Benjamin A Neely; Brian J Beck; Horacio Bach; David H Sherman; David C Lamb; Steven L Kelly; Michael R Waterman
The 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systems.
The Journal of biological chemistry 2003;278(14):12214-21.
2002: Beom Seok Kim; Thomas Ashton Cropp; Brian J Beck; David H Sherman; Kevin A Reynolds
Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin.
The Journal of biological chemistry 2002;277(50):48028-34.
2002: David H Sherman
New enzymes for "warheads".
Nature biotechnology 2002;20(10):984-5.
2002: Beom Seok Kim; Thomas Ashton Cropp; Galina Florova; Yuko Lindsay; David H Sherman; Kevin A Reynolds
An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis.
Biochemistry 2002;41(35):10827-33.
2002: Zunxue Chang; Patricia M Flatt; William H Gerwick; Viet-Anh Nguyen; Christine L Willis; David H Sherman
The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit.
Gene 2002;296(1-2):235-47.
2002: TW Martin; Zbigniew Dauter; Yancho Devedjiev; Peter J Sheffield; Filip Jelen; Min He; David H Sherman; Jacek Otlewski; Zygmunt S Derewenda; Urszula Derewenda
Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure (London, England : 1993) 2002;10(7):933-42.
2002: Brian J Beck; Yeo Joon Yoon; Kevin A Reynolds; David H Sherman
The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase.
Chemistry & biology 2002;9(5):575-83.
2002: Raymond P Baumann; David H Sherman; Alan C Sartorelli
Novel selection marker for mammalian cell transfection.
BioTechniques 2002;32(5):1030, 1032, 1034 passim.
2002: Yeo Joon Yoon; Brian J Beck; Beom Seok Kim; Han Young Kang; Kevin A Reynolds; David H Sherman
Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae.
Chemistry & biology 2002;9(2):203-14.
2002: Thomas Ashton Cropp; Beom S Kim; Brian J Beck; Yeo Joon Yoon; David H Sherman; Kevin A Reynolds
Recent developments in the production of novel polyketides by combinatorial biosynthesis.
Biotechnology & genetic engineering reviews 2002;19():159-72.
2001: YS Kyung; David H Sherman; Wei-Shou Hu
Simultaneous analysis of spatio-temporal gene expression for cephamycin biosynthesis in Streptomyces clavuligerus.
Biotechnology progress 2001;17(6):1000-7.
2001: Q Zhang; David H Sherman
Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae.
Journal of natural products 2001;64(11):1447-50.
2001: Raymond P Baumann; William F Hodnick; Helen A Seow; Michael F Belcourt; S Rockwell; David H Sherman; Alan C Sartorelli
Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
Cancer research 2001;61(21):7770-6.
2001: Philip G Penketh; William F Hodnick; Michael F Belcourt; Krishnamurthy Shyam; David H Sherman; Alan C Sartorelli
Inhibition of DNA cross-linking by mitomycin C by peroxidase-mediated oxidation of mitomycin C hydroquinone.
The Journal of biological chemistry 2001;276(37):34445-52.
2001: M Varoglu; Y Mao; David H Sherman
Mapping the mitomycin biosynthetic pathway by functional analysis of the MitM aziridine N-methyltransferase.
Journal of the American Chemical Society 2001;123(27):6712-3.
2001: D J Wilson; Y Xue; Kevin A Reynolds; David H Sherman
Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae.
Journal of bacteriology 2001;183(11):3468-75.
2001: YS Kyung; Wei-Shou Hu; David H Sherman
Analysis of temporal and spatial expression of the CcaR regulatory element in the cephamycin C biosynthetic pathway using green fluorescent protein.
Molecular microbiology 2001;40(3):530-41.
2001: M He; PJ Sheldon; David H Sherman
Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):926-31.
2001: S Chen; J B Roberts; Y Xue; David H Sherman; Kevin A Reynolds
The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide.
Gene 2001;263(1-2):255-64.
2001: Y Xue; David H Sherman
Biosynthesis and combinatorial biosynthesis of pikromycin-related macrolides in Streptomyces venezuelae.
Metabolic engineering 2001;3(1):15-26.
2000: S Chen; Y Xue; David H Sherman; Kevin A Reynolds
Mechanisms of molecular recognition in the pikromycin polyketide synthase.
Chemistry & biology 2000;7(12):907-18.
2000: anurag khetan; Wei-Shou Hu; David H Sherman
Heterogeneous distribution of lysine 6-aminotransferase during cephamycin C biosynthesis in Streptomyces clavuligerus demonstrated using green fluorescent protein as a reporter.
Microbiology (Reading, England) 2000;146 ( Pt 8)():1869-80.
2000: M He; M Varoglu; David H Sherman
Structural modeling and site-directed mutagenesis of the actinorhodin beta-ketoacyl-acyl carrier protein synthase.
Journal of bacteriology 2000;182(9):2619-23.
2000: Y Xue; D Wilson; David H Sherman
Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides.
Gene 2000;245(1):203-11.
2000: Y Xue; David H Sherman
Alternative modular polyketide synthase expression controls macrolactone structure.
Nature 2000;403(6769):571-5.
1999: L Han; anurag khetan; Wei-Shou Hu; David H Sherman
Time-lapsed confocal microscopy reveals temporal and spatial expression of the lysine epsilon-aminotransferase gene in Streptomyces clavuligerus.
Molecular microbiology 1999;34(5):878-86.
1999: anurag khetan; L H Malmberg; YS Kyung; David H Sherman; Wei-Shou Hu
Precursor and cofactor as a check valve for cephamycin biosynthesis in Streptomyces clavuligerus.
Biotechnology progress 1999;15(6):1020-7.
1999: Michael F Belcourt; Philip G Penketh; William F Hodnick; D A Johnson; David H Sherman; S Rockwell; Alan C Sartorelli
Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10489-94.
1999: S A Borisova; L Zhao; David H Sherman; Hung-wen Liu
Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety.
Organic letters 1999;1(1):133-6.
1999: PJ Sheldon; Y Mao; M He; David H Sherman
Mitomycin resistance in Streptomyces lavendulae includes a novel drug-binding-protein-dependent export system.
Journal of bacteriology 1999;181(8):2507-12.
1999: Y Mao; M Varoglu; David H Sherman
Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.
Chemistry & biology 1999;6(4):251-63.
1999: Y Mao; M Varoglu; David H Sherman
Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C.
Journal of bacteriology 1999;181(7):2199-208.
1998: Y Xue; D Wilson; L Zhao; H w Liu; David H Sherman
Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.
Chemistry & biology 1998;5(11):661-7.
1998: Y Xue; L Zhao; H W Liu; David H Sherman
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12111-6.
1998: A Bedekar; R M Zink; David H Sherman; T V Line; J F Van Pilsum
The comparative amino acid sequences, substrate specificities and gene or cDNA nucleotide sequences of some prokaryote and eukaryote amidinotransferases: implications for evolution.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1998;119(4):677-90.
1998: M D Williams; J A Rahn; Stuart Smith; Anil K Joshi; David H Sherman
Production of a polyhydroxyalkanoate biopolymer in insect cells with a modified eucaryotic Fatty Acid synthase.
Applied and environmental microbiology 1998;64(1):383.
1997: PJ Sheldon; D A Johnson; P R August; H W Liu; David H Sherman
Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae.
Journal of bacteriology 1997;179(5):1796-804.
1996: P R August; J A Rahn; Michael C Flickinger; David H Sherman
Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae.
Gene 1996;175(1-2):261-7.
1996: M D Williams; J A Rahn; David H Sherman
Production of a polyhydroxyalkanoate biopolymer in insect cells with a modified eucaryotic fatty acid synthase.
Applied and environmental microbiology 1996;62(7):2540-6.
1996: anurag khetan; L H Malmberg; David H Sherman; Wei-Shou Hu
Metabolic engineering of cephalosporin biosynthesis in Streptomyces clavuligerus.
Annals of the New York Academy of Sciences 1996;782():17-24.
1996: M D Williams; Angela M Fieno; Raymond A Grant; David H Sherman
Expression and analysis of a bacterial poly(hydroxyalkanoate) synthase in insect cells using a baculovirus system.
Protein expression and purification 1996;7(2):203-11.
1995: L H Malmberg; Wei-Shou Hu; David H Sherman
Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus.
Applied microbiology and biotechnology 1995;44(1-2):198-205.
1995: John Crosby; David H Sherman; Maureen J Bibb; W Peter Revill; David A Hopwood; Thomas J Simpson
Polyketide synthase acyl carrier proteins from Streptomyces: expression in Escherichia coli, purification and partial characterisation.
Biochimica et biophysica acta 1995;1251(1):32-42.
1995: E S Kim; K D Cramer; A L Shreve; David H Sherman
Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species.
Journal of bacteriology 1995;177(5):1202-7.
1994: P R August; Michael C Flickinger; David H Sherman
Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae.
Journal of bacteriology 1994;176(14):4448-54.
1994: Maureen J Bibb; David H Sherman; S Omura; David A Hopwood
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.
Gene 1994;142(1):31-9.
1994: E S Kim; Maureen J Bibb; M J Butler; David A Hopwood; David H Sherman
Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus.
Gene 1994;141(1):141-2.
1994: E S Kim; David A Hopwood; David H Sherman
Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants.
Journal of bacteriology 1994;176(6):1801-4.
1993: L H Malmberg; Wei-Shou Hu; David H Sherman
Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis.
Journal of bacteriology 1993;175(21):6916-24.
1993: Chaitan Khosla; R McDaniel; S Ebert-Khosla; R Torres; David H Sherman; Maureen J Bibb; David A Hopwood
Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins.
Journal of bacteriology 1993;175(8):2197-204.
1992: L H Malmberg; David H Sherman; Wei-Shou Hu
Analysis of rate-limiting reactions in cephalosporin biosynthesis.
Annals of the New York Academy of Sciences 1992;665():16-26.
1992: David H Sherman; E S Kim; Maureen J Bibb; David A Hopwood
Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway.
Journal of bacteriology 1992;174(19):6184-90.
1992: T J Arrowsmith; Francisco Malpartida; David H Sherman; A Birch; David A Hopwood; J A Robinson
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.
Molecular & general genetics : MGG 1992;234(2):254-64.
1990: David A Hopwood; David H Sherman
Molecular genetics of polyketides and its comparison to fatty acid biosynthesis.
Annual review of genetics 1990;24():37-66.
1989: David H Sherman; Francisco Malpartida; Maureen J Bibb; H M Kieser; M J Bibb; David A Hopwood
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.
The EMBO journal 1989;8(9):2717-25.
1988: G L Waneck; David H Sherman; Paul W Kincade; M G Low; R A Flavell
Molecular mapping of signals in the Qa-2 antigen required for attachment of the phosphatidylinositol membrane anchor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):577-81.