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Michael Sherman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Anatomy

Cell Line

Living Beings

Saccharomyces cerevisiae

Disorders

Neurodegenerative Diseases

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Network (preview)

Co-Publications
Name
22
Gabai, Vladimir
17
Meriin, Anatoli
13
Yaglom, Julia
8
Mosser, Dick
6
Chernoff, Yury
6
Volloch, Vladimir
4
O'Callaghan-Sunol, Cornelia
4
Goldberg, Alfred
3
Kazantsev, Aleksey
3
Massie, Bernard
3
Rits, S
3
Newnam, Gary
3
Zhang, Xiaoqian
2
Porco, John
2
Costello, Catherine

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Publications

TOP 3
Wang Yan; Meriin Anatoli B; Zaarur Nava; Romanova Nina V; Chernoff Yury O; Costello Catherine E; Sherman Michael Y
Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery.
Gabai Vladimir L; Yaglom Julia A; Waldman Todd; Sherman Michael Y
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.
Zaarur Nava; Meriin Anatoli B; Gabai Vladimir L; Sherman Michael Y
Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1.

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All Publications

2009: Wang Yan; Meriin Anatoli B; Zaarur Nava; Romanova Nina V; Chernoff Yury O; Costello Catherine E; Sherman Michael Y
Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(2):451-63.
2009: Gabai Vladimir L; Yaglom Julia A; Waldman Todd; Sherman Michael Y
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.
Molecular and cellular biology 2009;29(2):559-69.
2008: Zaarur Nava; Meriin Anatoli B; Gabai Vladimir L; Sherman Michael Y
Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1.
The Journal of biological chemistry 2008;283(41):27575-84.
2008: Gabai Vladimir L; O'Callaghan-Sunol Cornelia; Meng Le; Sherman Michael Y; Yaglom Julia
Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses.
Cancer research 2008;68(6):1834-42.
2007: O'Callaghan-Sunol Cornelia; Gabai Vladimir L; Sherman Michael Y
Hsp27 modulates p53 signaling and suppresses cellular senescence.
Cancer research 2007;67(24):11779-88.
2007: Meriin Anatoli B; Zhang XiaoQian; Alexandrov Ilya M; Salnikova Alexandra B; Ter-Avanesian Michael D; Chernoff Yury O; Sherman Michael Y
Endocytosis machinery is involved in aggregation of proteins with expanded polyglutamine domains.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1915-25.
2007: Wang Yan; Meriin Anatoli B; Costello Catherine E; Sherman Michael Y
Characterization of proteins associated with polyglutamine aggregates: a novel approach towards isolation of aggregates from protein conformation disorders.
Prion 2007;1(2):128-35.
2007: Yaglom Julia A; Gabai Vladimir L; Sherman Michael Y
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways.
Cancer research 2007;67(5):2373-81.
2006: O'Callaghan-Sunol Cornelia; Sherman Michael Y
Heat shock transcription factor (HSF1) plays a critical role in cell migration via maintaining MAP kinase signaling.
Cell cycle (Georgetown, Tex.) 2006;5(13):1431-7.
2006: Sherman Michael Y; Gabai Vladimir L
Multiple thermometers in mammalian cells: why do cells from homeothermic organisms need to measure temperature?
Science's STKE : signal transduction knowledge environment 2006;2006(328):pe16.
2006: Zaarur Nava; Gabai Vladimir L; Porco John A; Calderwood Stuart; Sherman Michael Y
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors.
Cancer research 2006;66(3):1783-91.
2006: Ganusova Elena E; Ozolins Laura N; Bhagat Srishti; Newnam Gary P; Wegrzyn Renee D; Sherman Michael Y; Chernoff Yury O
Modulation of prion formation, aggregation, and toxicity by the actin cytoskeleton in yeast.
Molecular and cellular biology 2006;26(2):617-29.
2005: Lei Xiaoguang; Zaarur Nava; Sherman Michael Y; Porco John A
Stereocontrolled synthesis of a complex library via elaboration of angular epoxyquinol scaffolds.
The Journal of organic chemistry 2005;70(16):6474-83.
2005: Meriin A B; Sherman M Y
Role of molecular chaperones in neurodegenerative disorders.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(5):403-19.
2005: Gokhale Kavita C; Newnam Gary P; Sherman Michael Y; Chernoff Yury O
Modulation of prion-dependent polyglutamine aggregation and toxicity by chaperone proteins in the yeast model.
The Journal of biological chemistry 2005;280(24):22809-18.
2005: Gabai Vladimir L; Budagova Karine R; Sherman Michael Y
Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents.
Oncogene 2005;24(20):3328-38.
2005: Zhang Xiaoqian; Smith Donna L; Meriin Anatoli B; Engemann Sabine; Russel Deborah E; Roark Margo; Washington Shetia L; Maxwell Michele M; Marsh J Lawrence; Thompson Leslie Michels; Wanker Erich E; Young Anne B; Housman David E; Bates Gillian P; Sherman Michael Y; Kazantsev Aleksey G
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):892-7.
2004: Sherman Michael Y
Yeast prions: protein aggregation is not enough.
PLoS biology 2004;2(4):E125.
2003: Yaglom Julia A; Ekhterae Daryoush; Gabai Vladimir L; Sherman Michael Y
Regulation of necrosis of H9c2 myogenic cells upon transient energy deprivation. Rapid deenergization of mitochondria precedes necrosis and is controlled by reactive oxygen species, stress kinase JNK, HSP72 and ARC.
The Journal of biological chemistry 2003;278(50):50483-96.
2003: Meriin Anatoli B; Zhang Xiaoqian; Miliaras Nicholas B; Kazantsev Alex; Chernoff Yury O; McCaffery J Michael; Wendland Beverly; Sherman Michael Y
Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis.
Molecular and cellular biology 2003;23(21):7554-65.
2003: Yaglom Julia; O'Callaghan-Sunol Cornelia; Gabai Vladimir; Sherman Michael Y
Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72.
Molecular and cellular biology 2003;23(11):3813-24.
2003: Sherman Michael Y; Muchowski Paul J
Making yeast tremble: yeast models as tools to study neurodegenerative disorders.
Neuromolecular medicine 2003;4(1-2):133-46.
2002: Meriin Anatoli B; Zhang Xiaoqian; He Xiangwei; Newnam Gary P; Chernoff Yury O; Sherman Michael Y
Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1.
The Journal of cell biology 2002;157(6):997-1004.
2002: Gabai Vladimir L; Mabuchi Katsuhide; Mosser Dick D; Sherman Michael Y
Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis.
Molecular and cellular biology 2002;22(10):3415-24.
2002: Gabai Vladimir L; Sherman Michael Y
Invited review: Interplay between molecular chaperones and signaling pathways in survival of heat shock.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(4):1743-8.
2001: Meriin A B; Mabuchi K; Gabai V L; Yaglom J A; Kazantsev A; Sherman M Y
Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1.
The Journal of cell biology 2001;153(4):851-64.
2001: Sherman M Y; Goldberg A L
Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases.
Neuron 2001;29(1):15-32.
2000: Gabai V L; Meriin A B; Yaglom J A; Wei J Y; Mosser D D; Sherman M Y
Suppression of stress kinase JNK is involved in HSP72-mediated protection of myogenic cells from transient energy deprivation. HSP72 alleviates the stewss-induced inhibition of JNK dephosphorylation.
The Journal of biological chemistry 2000;275(48):38088-94.
2000: Mosser D D; Caron A W; Bourget L; Meriin A B; Sherman M Y; Morimoto R I; Massie B
The chaperone function of hsp70 is required for protection against stress-induced apoptosis.
Molecular and cellular biology 2000;20(19):7146-59.
2000: Gabai V L; Yaglom J A; Volloch V; Meriin A B; Force T; Koutroumanis M; Massie B; Mosser D D; Sherman M Y
Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death.
Molecular and cellular biology 2000;20(18):6826-36.
2000: Volloch V; Gabai V L; Rits S; Force T; Sherman M Y
HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK.
Cell stress & chaperones 2000;5(2):139-47.
1999: Volloch V; Gabai V L; Rits S; Sherman M Y
ATPase activity of the heat shock protein hsp72 is dispensable for its effects on dephosphorylation of stress kinase JNK and on heat-induced apoptosis.
FEBS letters 1999;461(1-2):73-6.
1999: Yaglom J A; Gabai V L; Meriin A B; Mosser D D; Sherman M Y
The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage.
The Journal of biological chemistry 1999;274(29):20223-8.
1999: Volloch V Z; Sherman M Y
Oncogenic potential of Hsp72.
Oncogene 1999;18(24):3648-51.
1999: Meriin A B; Yaglom J A; Gabai V L; Zon L; Ganiatsas S; Mosser D D; Zon L; Sherman M Y
Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72.
Molecular and cellular biology 1999;19(4):2547-55.
1998: Volloch V; Mosser D D; Massie B; Sherman M Y
Reduced thermotolerance in aged cells results from a loss of an hsp72-mediated control of JNK signaling pathway.
Cell stress & chaperones 1998;3(4):265-71.
1998: Gabai V L; Meriin A B; Yaglom J A; Volloch V Z; Sherman M Y
Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and aging.
FEBS letters 1998;438(1-2):1-4.
1998: Meriin A B; Gabai V L; Yaglom J; Shifrin V I; Sherman M Y
Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis.
The Journal of biological chemistry 1998;273(11):6373-9.
1997: Gabai V L; Meriin A B; Mosser D D; Caron A W; Rits S; Shifrin V I; Sherman M Y
Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance.
The Journal of biological chemistry 1997;272(29):18033-7.
1996: Lee D H; Sherman M Y; Goldberg A L
Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(9):4773-81.
1996: Yaglom J A; Goldberg A L; Finley D; Sherman M Y
The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation.
Molecular and cellular biology 1996;16(7):3679-84.
1993: Sherman M Y; Goldberg A L
Heat shock of Escherichia coli increases binding of dnaK (the hsp70 homolog) to polypeptides by promoting its phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8648-52.
1991: Sherman M Y; Goldberg A L
Formation in vitro of complexes between an abnormal fusion protein and the heat shock proteins from Escherichia coli and yeast mitochondria.
Journal of bacteriology 1991;173(22):7249-56.

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