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Tomas Blom

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Tomas Blom; Jonathan D Cooper; Matti Jauhiainen; Aija Kyttälä; Mia-Lisa Schmiedt; Jarkko Soronen; Jaana Tyynelä; Andrew M Wong; Anu Jalanko
Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice.
Mia-Lisa Schmiedt; Carina von Schantz-Fant; Andrew Wong; Matti Jauhiainen; Outi Kopra; Mervi Kuronen; Tomas Blom; Tomas Blom; Jonathan D Cooper; Elina Ikonen; Anu Jalanko
Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism.
Tomas Blom; Nina Bergelin; Annika Meinander; Christoffer Löf; J Peter Slotte; John E Eriksson; Kid Törnquist
An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.

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2013: Tomas Blom; Jonathan D Cooper; Matti Jauhiainen; Aija Kyttälä; Mia-Lisa Schmiedt; Jarkko Soronen; Jaana Tyynelä; Andrew M Wong; Anu Jalanko
Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice.
Disease models & mechanisms 2013;6(2):342-57.
2012: Mia-Lisa Schmiedt; Carina von Schantz-Fant; Andrew Wong; Matti Jauhiainen; Outi Kopra; Mervi Kuronen; Tomas Blom; Tomas Blom; Jonathan D Cooper; Elina Ikonen; Anu Jalanko
Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism.
Neurobiology of disease 2012;46(1):19-29.
2010: Tomas Blom; Nina Bergelin; Annika Meinander; Christoffer Löf; J Peter Slotte; John E Eriksson; Kid Törnquist
An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.
BMC cell biology 2010;11():45.
2009: N Bergelin; Tomas Blom; J Heikkilä; C Löf; C Alam; S Balthasar; J Peter Slotte; A Hinkkanen; Kid Törnquist
Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-alpha and ERK1/2.
Endocrinology 2009;150(5):2055-63.
2008: Christoffer Löf; Tomas Blom; Kid Törnquist
Overexpression of TRPC3 reduces the content of intracellular calcium stores in HEK-293 cells.
Journal of cellular physiology 2008;216(1):245-52.
2007: Emad Afrasiabi; Tomas Blom; Sonja Balthasar; Kid Törnquist
Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase.
Molecular and cellular endocrinology 2007;274(1-2):43-52.
2006: Kaisu Luiro; Outi Kopra; Tomas Blom; Massimiliano Gentile; Hannah M Mitchison; Iiris Hovatta; Kid Törnquist; Anu Jalanko
Batten disease (JNCL) is linked to disturbances in mitochondrial, cytoskeletal, and synaptic compartments.
Journal of neuroscience research 2006;84(5):1124-38.
2006: Emad Afrasiabi; Tomas Blom; Elina Ekokoski; Raimo K Tuominen; Kid Törnquist
Sphingosylphosphorylcholine enhances calcium entry in thyroid FRO cells by a mechanism dependent on protein kinase C.
Cellular signalling 2006;18(10):1671-8.
2006: Tomas Blom; Nina Bergelin; J Peter Slotte; Kid Törnquist
Sphingosine kinase regulates voltage operated calcium channels in GH4C1 rat pituitary cells.
Cellular signalling 2006;18(9):1366-75.
2005: Tomas Blom; J Peter Slotte; Stuart M Pitson; Kid Törnquist
Enhancement of intracellular sphingosine-1-phosphate production by inositol 1,4,5-trisphosphate-evoked calcium mobilisation in HEK-293 cells: endogenous sphingosine-1-phosphate as a modulator of the calcium response.
Cellular signalling 2005;17(7):827-36.
2004: Dan Gratschev; Tomas Blom; Sonja Björklund; Kid Törnquist
Phosphatase inhibition reveals a calcium entry pathway dependent on protein kinase A in thyroid FRTL-5 cells: comparison with store-operated calcium entry.
The Journal of biological chemistry 2004;279(48):49816-24.
2004: Kid Törnquist; Tomas Blom; Ramin Shariatmadari; Michael Pasternack
Ceramide 1-phosphate enhances calcium entry through voltage-operated calcium channels by a protein kinase C-dependent mechanism in GH4C1 rat pituitary cells.
The Biochemical journal 2004;380(Pt 3):661-8.