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Huafang Shi

Research Profile

Phenomena

RNA Interference

Chemicals & Drugs

Concepts & Ideas

Molecular Sequence Data

Physiology

Genes & Molecular Sequences

Genes, Protozoan

Procedures

Electroporation

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Publications

TOP 3
Vanessa D Atayde; Stephen M Beverley; Nicholas Carriero; Joseph B Franklin; Lon-Fye Lye; Timothy Notton; Katherine Owens; Huafang Shi; Christian Tschudi; Elisabetta Ullu
The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway.
Christian Tschudi; Joseph B Franklin; Huafang Shi; Elisabetta Ullu
Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei.
Rebecca L Barnes; Nikolay G Kolev; Huafang Shi; Christian Tschudi; Elisabetta Ullu
Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery.

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All Publications

2013: Vanessa D Atayde; Stephen M Beverley; Nicholas Carriero; Joseph B Franklin; Lon-Fye Lye; Timothy Notton; Katherine Owens; Huafang Shi; Christian Tschudi; Elisabetta Ullu
The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway.
Molecular microbiology 2013;87(3):580-93.
2012: Christian Tschudi; Joseph B Franklin; Huafang Shi; Elisabetta Ullu
Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei.
BMC genomics 2012;13():427.
2012: Rebecca L Barnes; Nikolay G Kolev; Huafang Shi; Christian Tschudi; Elisabetta Ullu
Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery.
PLoS pathogens 2012;8(5):e1002678.
2010: Sachin Kumar Gupta; Avraham Hury; Yaara Ziporen; Huafang Shi; Elisabetta Ullu; Shulamit Michaeli
Small nucleolar RNA interference in Trypanosoma brucei: mechanism and utilization for elucidating the function of snoRNAs.
Nucleic acids research 2010;38(20):7236-47.
2010: Nikolay G Kolev; Joseph B Franklin; Shai Carmi; Huafang Shi; Shulamit Michaeli; Christian Tschudi
The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution.
PLoS pathogens 2010;6(9):e1001090.
2009: Huafang Shi; Nathalie Chamond; Appolinaire Djikeng; Christian Tschudi; Elisabetta Ullu
RNA interference in Trypanosoma brucei: role of the n-terminal RGG domain and the polyribosome association of argonaute.
The Journal of biological chemistry 2009;284(52):36511-20.
2009: Kristin L Patrick; Huafang Shi; Nikolay G Kolev; Klaus Ersfeld; Christian Tschudi; Elisabetta Ullu
Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17933-8.
2008: Kristin Patrick; Paula M Luz; Jia-Peng Ruan; Huafang Shi; Elisabetta Ullu; Christian Tschudi
Genomic rearrangements and transcriptional analysis of the spliced leader-associated retrotransposon in RNA interference-deficient Trypanosoma brucei.
Molecular microbiology 2008;67(2):435-47.
2007: Huafang Shi; Christian Tschudi; Elisabetta Ullu
Depletion of newly synthesized Argonaute1 impairs the RNAi response in Trypanosoma brucei.
RNA (New York, N.Y.) 2007;13(7):1132-9.
2006: Huafang Shi; Christian Tschudi; Elisabetta Ullu
An unusual Dicer-like1 protein fuels the RNA interference pathway in Trypanosoma brucei.
RNA (New York, N.Y.) 2006;12(12):2063-72.
2006: Huafang Shi; Christian Tschudi; Elisabetta Ullu
Functional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2.
RNA (New York, N.Y.) 2006;12(6):943-7.
2005: Huafang Shi; Appolinaire Djikeng; Nathalie Chamond; Huân M Ngô; Christian Tschudi; Elisabetta Ullu
Repression of gene expression by the coliphage MS2 coat protein in Trypanosoma brucei.
Molecular and biochemical parasitology 2005;144(1):119-22.
2004: Huafang Shi; Nathalie Chamond; Christian Tschudi; Elisabetta Ullu
Selection and characterization of RNA interference-deficient trypanosomes impaired in target mRNA degradation.
Eukaryotic cell 2004;3(6):1445-53.
2004: Huafang Shi; Elisabetta Ullu; Christian Tschudi
Function of the Trypanosome Argonaute 1 protein in RNA interference requires the N-terminal RGG domain and arginine 735 in the Piwi domain.
The Journal of biological chemistry 2004;279(48):49889-93.
2004: Huafang Shi; Appolinaire Djikeng; Christian Tschudi; Elisabetta Ullu
Argonaute protein in the early divergent eukaryote Trypanosoma brucei: control of small interfering RNA accumulation and retroposon transcript abundance.
Molecular and cellular biology 2004;24(1):420-7.
2003: Christian Tschudi; Appolinaire Djikeng; Huafang Shi; Elisabetta Ullu
In vivo analysis of the RNA interference mechanism in Trypanosoma brucei.
Methods (San Diego, Calif.) 2003;30(4):304-12.
2003: Appolinaire Djikeng; Huafang Shi; Christian Tschudi; Shuiyuan Shen; Elisabetta Ullu
An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei.
RNA (New York, N.Y.) 2003;9(7):802-8.
2002: Huafang Shi; Steven Wormsley; Christian Tschudi; Elisabetta Ullu
Efficient transposition of preformed synaptic Tn5 complexes in Trypanosoma brucei.
Molecular and biochemical parasitology 2002;121(1):141-4.
2002: Elisabetta Ullu; Appolinaire Djikeng; Huafang Shi; Christian Tschudi
RNA interference: advances and questions.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2002;357(1417):65-70.
2001: Appolinaire Djikeng; Huafang Shi; Christian Tschudi; Elisabetta Ullu
RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs.
RNA (New York, N.Y.) 2001;7(11):1522-30.
2000: Huafang Shi; Peter B Moore
The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited.
RNA (New York, N.Y.) 2000;6(8):1091-105.
2000: Huafang Shi; Appolinaire Djikeng; T Mark; E Wirtz; Christian Tschudi; Elisabetta Ullu
Genetic interference in Trypanosoma brucei by heritable and inducible double-stranded RNA.
RNA (New York, N.Y.) 2000;6(7):1069-76.
2000: G Mair; Huafang Shi; Hongjie Li; Appolinaire Djikeng; H O Aviles; Joseph Bishop; Franco Falcone; L Cristina Gavrilescu; J L Montgomery; Maria Isabel Santori; L S Stern; Zefeng Wang; Elisabetta Ullu; Christian Tschudi
A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA.
RNA (New York, N.Y.) 2000;6(2):163-9.
1998: C D Green; KS Long; Huafang Shi; Sandra L Wolin
Binding of the 60-kDa Ro autoantigen to Y RNAs: evidence for recognition in the major groove of a conserved helix.
RNA (New York, N.Y.) 1998;4(7):750-65.
1997: D J Van Horn; CJ Yoo; Dahai Xue; Huafang Shi; Sandra L Wolin
The La protein in Schizosaccharomyces pombe: a conserved yet dispensable phosphoprotein that functions in tRNA maturation.
RNA (New York, N.Y.) 1997;3(12):1434-43.
1996: Huafang Shi; C A O'Brien; D J Van Horn; Sandra L Wolin
A misfolded form of 5S rRNA is complexed with the Ro and La autoantigens.
RNA (New York, N.Y.) 1996;2(8):769-84.