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Brunhilde Blömeke

Research Profile

Chemicals & Drugs

Disorders

Dermatitis, Allergic Contact

Anatomy

Physiology

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Publications

TOP 3
Laura M Pot; Simone M Scheitza; Pieter-Jan Coenraads; Brunhilde Blömeke
Penetration and haptenation of p-phenylenediamine.
Dorothea Dierolf; Simone Scheitza; Jutta Bonifas; Brunhilde Blömeke
Cyanamide-mediated Inhibition of N-acetyltransferase 1.
Carsten Goebel; Brunhilde Blömeke; Pieter-Jan Coenraads; Thomas L Diepgen; Rolf Fautz; Anne Fuchs; G Frank Gerberick; Maya Krasteva; Jean-Francois Nicolas; Jacquemine Pungier; Harald Schlatter; Axel Schnuch; Werner Schuh; James S Taylor; Ian Kimber
Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients.

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All Publications

2013: Laura M Pot; Simone M Scheitza; Pieter-Jan Coenraads; Brunhilde Blömeke
Penetration and haptenation of p-phenylenediamine.
Contact dermatitis 2013;68(4):193-207.
2012: Dorothea Dierolf; Simone Scheitza; Jutta Bonifas; Brunhilde Blömeke
Cyanamide-mediated Inhibition of N-acetyltransferase 1.
Toxicology 2012;302(1):1-10.
2012: Carsten Goebel; Brunhilde Blömeke; Pieter-Jan Coenraads; Thomas L Diepgen; Rolf Fautz; Anne Fuchs; G Frank Gerberick; Maya Krasteva; Jean-Francois Nicolas; Jacquemine Pungier; Harald Schlatter; Axel Schnuch; Werner Schuh; James S Taylor; Ian Kimber
Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients.
Regulatory toxicology and pharmacology : RTP 2012;64(3):459-65.
2012: Michaela Kalmes; Brunhilde Blömeke
Impact of eugenol and isoeugenol on AhR translocation, target gene expression, and proliferation in human HaCaT keratinocytes.
Journal of toxicology and environmental health. Part A 2012;75(8-10):478-91.
2012: Simone Scheitza; Jutta Bonifas; Brunhilde Blömeke
Variable NAT1 enzyme activity in long-term cultured human HaCaT keratinocytes.
Journal of toxicology and environmental health. Part A 2012;75(8-10):471-7.
2011: Sebastian G Klein; Tommaso Serchi; Brunhilde Blömeke; Jenny Hennen; Arno C Gutleb
Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(8):1516-34.
2011: Christiaan V Bakker; Brunhilde Blömeke; Pieter-Jan Coenraads; Marie-Louise Schuttelaar
Ascaridole, a sensitizing component of tea tree oil, patch tested at 1% and 5% in two series of patients.
Contact dermatitis 2011;65(4):240-1.
2011: Jenny Hennen; Michaela Kalmes; Aurelia Oberli; Thomas Schettgen; Pierre Aeby; Carsten Goebel; Brunhilde Blömeke
Cross talk between keratinocytes and dendritic cells: impact on the prediction of sensitization.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(2):501-10.
2011: Michaela Kalmes; Judith Clemens; Jenny Hennen; Brunhilde Blömeke
Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle progression in human HaCaT keratinocytes.
Biological chemistry 2011;392(7):643-51.
2010: C Goebel; Pieter-Jan Coenraads; H Rothe; G Kunze; M Kock; H Schlatter; G Frank Gerberick; Brunhilde Blömeke
Elicitation of the immune response to p-phenylenediamine in allergic patients: the role of dose and exposure time.
The British journal of dermatology 2010;163(6):1205-11.
2010: Jutta Bonifas; Simone Scheitza; Judith Clemens; Brunhilde Blömeke
Characterization of N-acetyltransferase 1 activity in human keratinocytes and modulation by para-phenylenediamine.
The Journal of pharmacology and experimental therapeutics 2010;334(1):318-26.
2010: Jutta Bonifas; Jenny Hennen; Dorothea Dierolf; Michaela Kalmes; Brunhilde Blömeke
Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: implications for the development of in vitro techniques for predictive testing of contact sensitizers.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(3):973-80.
2009: Brunhilde Blömeke; R Brans; Pieter-Jan Coenraads; H Dickel; Thomas Bruckner; D W Hein; M Heesen; Hans F Merk; Yo Kawakubo
Para-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes.
The British journal of dermatology 2009;161(5):1130-5.
2009: Axel Meyer; Brunhilde Blömeke; Klaus Fischer
Determination of p-phenylenediamine and its metabolites MAPPD and DAPPD in biological samples using HPLC-DAD and amperometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(16-17):1627-33.
2009: Dominik Lermen; Brunhilde Blömeke; Robert Browne; Ann Clarke; Paul W Dyce; Thomas Fixemer; Günter R Fuhr; William V Holt; Katarina Jewgenow; Rhiannon E Lloyd; Stefan Lötters; Martin Paulus; Gordon McGregor Reid; Daniel H Rapoport; David Rawson; Jennifer Ringleb; Oliver A Ryder; Gabriele Spörl; Thomas Schmitt; Michael Veith; Paul Müller
Cryobanking of viable biomaterials: implementation of new strategies for conservation purposes.
Molecular ecology 2009;18(6):1030-3.
2009: Brunhilde Blömeke; R Brans; H Dickel; T Bruckner; S Erdmann; M Heesen; Hans F Merk; Pieter-Jan Coenraads
Association between TNFA-308 G/A polymorphism and sensitization to para-phenylenediamine: a case-control study.
Allergy 2009;64(2):279-83.
2009: Richard Brans; C Skazik; Hans F Merk; Brunhilde Blömeke
[Sensitisation to p-Phenylenediamine. Effects of metabolism and individual susceptibility].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2009;60(1):26-31.
2008: Claudia Skazik; Silke Grannemann; Liane Wilbers; Hans F Merk; Pieter-Jan Coenraads; Sebastian Breuer; Brunhilde Blömeke
Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances.
Contact dermatitis 2008;59(4):203-11.
2008: Ruth Moeller; Jutta Lichter; Brunhilde Blömeke
Impact of para-phenylenediamine on cyclooxygenases expression and prostaglandin formation in human immortalized keratinocytes (HaCaT).
Toxicology 2008;249(2-3):167-75.
2008: Brunhilde Blömeke; Tim Pietzsch; Hans F Merk
Elicitation response characteristics to mono- and to N,N'-diacetyl-para-phenylenediamine.
Contact dermatitis 2008;58(6):355-8.
2008: Gerhard Andreas Wiesmüller; Hiltrud Niggemann; Wibke Weissbach; Felix Riley; Zackaria Maarouf; Wolfgang Dott; Hanns Jürgen Kunert; Klaus Zerres; Thomas Eggermann; Brunhilde Blömeke
Sequence variations in subjects with self-reported multiple chemical sensitivity (sMCS): a case-control study.
Journal of toxicology and environmental health. Part A 2008;71(11-12):786-94.
2006: Michaela Kalmes; Andrea Neumeyer; Paola Rio; Helmut Hanenberg; Ellen Fritsche; Brunhilde Blömeke
Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT).
Biological chemistry 2006;387(9):1201-7.
2005: Mike Duisken; Dorina Benz; Thomas H Peiffer; Brunhilde Blömeke; Juliane Hollender
Metabolism of Delta(3)-carene by human cytochrome p450 enzymes: identification and characterization of two new metabolites.
Current drug metabolism 2005;6(6):593-601.
2005: Richard Brans; Heinrich Dickel; Thomas Bruckner; Pieter-Jan Coenraads; Michael Heesen; Hans F Merk; Brunhilde Blömeke
MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: a case-control study.
Toxicology 2005;212(2-3):148-54.
2005: Silke Grannemann; Olfert Landt; Sebastian Breuer; Brunhilde Blömeke
LightTyper assay with locked-nucleic-acid-modified oligomers for genotyping of the toll-like receptor 4 polymorphisms A896G and C1196T.
Clinical chemistry 2005;51(8):1523-5.
2005: Mike Duisken; Frank Sandner; Brunhilde Blömeke; Juliane Hollender
Metabolism of 1,8-cineole by human cytochrome P450 enzymes: identification of a new hydroxylated metabolite.
Biochimica et biophysica acta 2005;1722(3):304-11.
2005: Matthias Majetschak; Ulrich Krehmeier; Liljana Ostroverkh; Brunhilde Blömeke; Michael Schäfer
Alterations in leukocyte function following surgical trauma: differentiation of distinct reaction types and association with tumor necrosis factor gene polymorphisms.
Clinical and diagnostic laboratory immunology 2005;12(2):296-303.
2004: Richard Brans; Danute Laizane; Annika Khan; Brunhilde Blömeke
N-acetyltransferase 2 genotyping: an accurate and feasible approach for simultaneous detection of the most common NAT2 alleles.
Clinical chemistry 2004;50(7):1264-6.
2003: Motoko Tanaka-Nozaki; Takashi Tajiri; Noritake Tanaka; Kiyonori Furukawa; Hideaki Takasaki; Kazuyasu Yoshimura; Hideyuki Suzuki; Zenya Naito; Yuuichi Sugizaki; Hans F Merk; Brunhilde Blömeke; Shunji Kato
Intratumoral induction of thymidylate synthase mRNA by 5-FU in colorectal cancer patients: association with survival.
Oncology reports 2003;10(5):1425-9.
2002: Sonja Sieben; Yo Kawakubo; Tames Al Masaoudi; Hans F Merk; Brunhilde Blömeke
Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones.
The Journal of allergy and clinical immunology 2002;109(6):1005-11.
2001: Michael Heesen; Brunhilde Blömeke; B Schlüter; Nicole Heussen; Rolf Rossaint; Dagmar Kunz
Lack of association between the -260 C-->T promoter polymorphism of the endotoxin receptor CD14 gene and the CD14 density of unstimulated human monocytes and soluble CD14 plasma levels.
Intensive care medicine 2001;27(11):1770-5.
2001: Sonja Sieben; M Hertl; Tames Al Masaoudi; Hans F Merk; Brunhilde Blömeke
Characterization of T cell responses to fragrances.
Toxicology and applied pharmacology 2001;172(3):172-8.
2000: Michael Heesen; Dagmar Kunz; Rolf Rossaint; Brunhilde Blömeke
Real-time PCR assay with fluorescent hybridization probes for rapid genotyping of the CD14 promotor polymorphism.
Clinical chemistry 2000;46(11):1866-7.
2000: S Neemeshkanna; Olfert Landt; H F Merk; Brunhilde Blömeke
Fluorogenic probes to detect the A(-444)C transversion in the leukotriene C4 synthase promoter.
Clinical chemistry 2000;46(9):1438-9.
2000: Yo Kawakubo; Hans F Merk; T A Masaoudi; Sonja Sieben; Brunhilde Blömeke
N-Acetylation of paraphenylenediamine in human skin and keratinocytes.
The Journal of pharmacology and experimental therapeutics 2000;292(1):150-5.
1999: Brunhilde Blömeke; Sonja Sieben; D Spötter; Olfert Landt; Hans F Merk
Identification of N-acetyltransferase 2 genotypes by continuous monitoring of fluorogenic hybridization probes.
Analytical biochemistry 1999;275(1):93-7.
1999: Sonja Sieben; J M Baron; Brunhilde Blömeke; Hans F Merk
Multiple cytochrome P450-isoenzymes mRNA are expressed in dendritic cells.
International archives of allergy and immunology 1999;118(2-4):358-61.