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Eric Blomme

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Yi Yang; William M Bracken; Rita Ciurlionis; Kenneth Kowalkowski; Kennan C Marsh; Eric A G Blomme
N-vinylpyrrolidone dimer, a novel formulation excipient, causes hepatic and thyroid hypertrophy through the induction of hepatic microsomal enzymes in rats.
Michael J Liguori; Hong Liu; Kennan C Marsh; Jeffrey F Waring; Mark E Andracki; Eric A G Blomme; Rita Ciurlionis; Amy C Ditewig; Stella Doktor; Gerard Gagne; Murali Gopalakrishnan; Chih-Hung Lee; Yi Yang
AhR activation underlies the CYP1A autoinduction by A-998679 in rats.
Marcin Klapczynski; Kelly J Larson; Bruce E LeRoy; Sherry J Morgan; Eric A G Blomme; Bryan F Cox; Gerard Gagne; Eugene W Shek
Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models.

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2012: Yi Yang; William M Bracken; Rita Ciurlionis; Kenneth Kowalkowski; Kennan C Marsh; Eric A G Blomme
N-vinylpyrrolidone dimer, a novel formulation excipient, causes hepatic and thyroid hypertrophy through the induction of hepatic microsomal enzymes in rats.
Toxicology letters 2012;208(1):82-91.
2012: Michael J Liguori; Hong Liu; Kennan C Marsh; Jeffrey F Waring; Mark E Andracki; Eric A G Blomme; Rita Ciurlionis; Amy C Ditewig; Stella Doktor; Gerard Gagne; Murali Gopalakrishnan; Chih-Hung Lee; Yi Yang
AhR activation underlies the CYP1A autoinduction by A-998679 in rats.
Frontiers in genetics 2012;3():213.
2012: Marcin Klapczynski; Kelly J Larson; Bruce E LeRoy; Sherry J Morgan; Eric A G Blomme; Bryan F Cox; Gerard Gagne; Eugene W Shek
Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models.
Journal of pathology informatics 2012;3():20.
2011: Eric A G Blomme
The ARRIVE guidelines: a resource for authors and reviewers to ensure that submissions to The Veterinary Journal meet minimal expectations of completeness, accuracy and transparency.
Veterinary journal (London, England : 1997) 2011;189(3):237-8.
2011: Tracy L Carr; Rita Ciurlionis; Ivan Milicic; Katharine Whitney; Michael J Liguori; Scott E Warder; Marina I Strakhova; Eric A G Blomme
Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats.
Archives of toxicology 2011;85(5):513-23.
2011: Eric A G Blomme
Assessing renal function: some significant improvements on the horizon.
Veterinary journal (London, England : 1997) 2011;188(2):128-9.
2011: Meagan M Fricano; Paul Martin Jung; Michael J Liguori; Eric A G Blomme; Amy C Ditewig; Yi Yang
Global transcriptomic profiling using small volumes of whole blood: a cost-effective method for translational genomic biomarker identification in small animals.
International journal of molecular sciences 2011;12(4):2502-17.
2010: Eric A G Blomme; Brian B Spear
Theranostics in veterinary medicine: where are we heading?
Veterinary journal (London, England : 1997) 2010;185(3):237-8.
2010: Yi Yang; Annette J Dahly-Vernon; Eric A G Blomme; Jie Lai-Zhang; Dale J Kempf; Kennan Marsh; Yvette A Harrington; Steven H Nye; Darin L Evans; Richard J Roman; Howard J Jacob; Jeffrey F Waring
Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats.
Veterinary journal (London, England : 1997) 2010;185(1):75-82.
2010: Michael J Liguori; Amy C Ditewig; Jane F Maddox; James P Luyendyk; Lois D Lehman-McKeeman; David M Nelson; Vasanthi M Bhaskaran; Jeffrey F Waring; Patricia E Ganey; Robert A Roth; Eric A G Blomme
Comparison of TNFα to Lipopolysaccharide as an Inflammagen to Characterize the Idiosyncratic Hepatotoxicity Potential of Drugs: Trovafloxacin as an Example.
International journal of molecular sciences 2010;11(11):4697-714.
2009: Prasant Chandran; Madhavi Pai; Eric A G Blomme; Gin C Hsieh; Michael W Decker; Prisca Honore
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis.
European journal of pharmacology 2009;613(1-3):39-45.
2009: Eric A G Blomme; Yi Yang; Jeffrey F Waring
Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.
Toxicology letters 2009;186(1):22-31.
2009: Rahul Deshmukh; Eric A G Blomme
A dog is not a rat: importance of understanding species differences in drug absorption, distribution, metabolism and excretion (ADME).
Veterinary journal (London, England : 1997) 2009;179(1):8-9.
2008: Xiaomin Deng; Michael J Liguori; Erica M Sparkenbaugh; Jeffrey F Waring; Eric A G Blomme; Patricia E Ganey; Robert A Roth
Gene expression profiles in livers from diclofenac-treated rats reveal intestinal bacteria-dependent and -independent pathways associated with liver injury.
The Journal of pharmacology and experimental therapeutics 2008;327(3):634-44.
2008: Eric A G Blomme
Cancer stem cells: toward novel anti-cancer therapies?
Veterinary journal (London, England : 1997) 2008;177(3):303-4.
2008: Christine Healan-Greenberg; Jeffrey F Waring; Dale J Kempf; Eric A G Blomme; Rommel G Tirona; Richard B Kim
A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(3):500-7.
2008: Jeffrey F Waring; Yi Yang; Christine H Healan-Greenberg; Andrew L Adler; Robert Dickinson; Teresa McNally; Xiaojun Wang; Moshe Weitzberg; Xiangdong Xu; Andrew Lisowski; Scott E Warder; Yu Gui Gu; Bradley A Zinker; Eric A G Blomme; Heidi S Camp
Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway.
The Journal of pharmacology and experimental therapeutics 2008;324(2):507-16.
2008: Michael J Liguori; Eric A G Blomme; Jeffrey F Waring
Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(2):223-33.
2008: Eric A G Blomme; Rita Ciurlionis; Kennan Marsh; Jeffrey F Waring; Yi Yang
Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats.
Toxicology letters 2008;176(2):138-48.
2008: Wayne R Buck; Jeffrey F Waring; Eric A G Blomme
Use of traditional end points and gene dysregulation to understand mechanisms of toxicity: toxicogenomics in mechanistic toxicology.
Methods in molecular biology (Clifton, N.J.) 2008;460():23-44.
2007: Yu Gui Gu; Moshe Weitzberg; Richard F Clark; Xiangdong Xu; Qun Li; Nathan L Lubbers; Yi Yang; David W A Beno; Deborah L Widomski; Tianyuan Zhang; T Matthew Hansen; Robert F Keyes; Jeffrey F Waring; Sherry L Carroll; Xiaojun Wang; Rongqi Wang; Christine H Healan-Greenberg; Eric A G Blomme; Bruce A Beutel; Hing L Sham; Heidi S Camp
N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.
Journal of medicinal chemistry 2007;50(5):1078-82.
2006: Xiaomin Deng; Robert F Stachlewitz; Michael J Liguori; Eric A G Blomme; Jeffrey F Waring; James P Luyendyk; Jane F Maddox; Patricia E Ganey; Robert A Roth
Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1191-9.
2006: W Rachel Duan; Shem Patyna; Madeline A Kuhlmann; Shuanglian Li; Eric A G Blomme
A multitargeted receptor tyrosine kinase inhibitor, SU6668, does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2006;19(4):245-54.
2006: Jeffrey F Waring; Michael J Liguori; James P Luyendyk; Jane F Maddox; Patricia E Ganey; Robert F Stachlewitz; Colin North; Eric A G Blomme; Robert A Roth
Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1080-7.
2005: Mollisa M Elrick; Jeffrey A Kramer; Carl L Alden; Eric A G Blomme; Roderick T Bunch; Marc A Cabonce; Sandra W Curtiss; Larry D Kier; Kolaja Kyle; Charles P Rodi; Dale L Morris
Differential display in rat livers treated for 13 weeks with phenobarbital implicates a role for metabolic and oxidative stress in nongenotoxic carcinogenicity.
Toxicologic pathology 2005;33(1):118-26.
2004: Yi Yang; Eric A G Blomme; Jeffrey F Waring
Toxicogenomics in drug discovery: from preclinical studies to clinical trials.
Chemico-biological interactions 2004;150(1):71-85.
2004: Jeffrey A Kramer; Sandra W Curtiss; Kolaja Kyle; Carl L Alden; Eric A G Blomme; William C Curtiss; Julio C Davila; Carmen J Jackson; Roderick T Bunch
Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling.
Chemical research in toxicology 2004;17(4):463-70.
2004: Rani S Sellers; Bruce E LeRoy; Eric A G Blomme; Sarah H Tannehill-Gregg; Stephanie Corn; Thomas J Rosol
Effects of transforming growth factor-beta1 on parathyroid hormone-related protein mRNA expression and protein secretion in canine prostate epithelial, stromal, and carcinoma cells.
The Prostate 2004;58(4):366-73.
2003: Catherine S Tripp; Eric A G Blomme; Kevin S Chinn; Medora M Hardy; Peter LaCelle; Alice P Pentland
Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection.
The Journal of investigative dermatology 2003;121(4):853-61.
2003: Wenning Qin; Amy E Rudolph; Brian R Bond; Ricardo Rocha; Eric A G Blomme; Joseph J Goellner; John W Funder; Ellen G McMahon
Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure.
Circulation research 2003;93(1):69-76.
2003: Jeffrey A Kramer; Eric A G Blomme; Roderick T Bunch; Julio C Davila; Carmen J Jackson; Patrick F Jones; Kolaja Kyle; Sandra W Curtiss
Transcription profiling distinguishes dose-dependent effects in the livers of rats treated with clofibrate.
Toxicologic pathology 2003;31(4):417-31.
2003: S J Yan; Eric A G Blomme
In situ zymography: a molecular pathology technique to localize endogenous protease activity in tissue sections.
Veterinary pathology 2003;40(3):227-36.
2003: Eileen R Blasi; Ricardo Rocha; Amy E Rudolph; Eric A G Blomme; Melissa L Polly; Ellen G McMahon
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats.
Kidney international 2003;63(5):1791-800.
2003: Medora M Hardy; Eric A G Blomme; Andrew Lisowski; Kevin S Chinn; Amy Jones; Janet M Harmon; Alan Opsahl; Richard L Ornberg; Catherine S Tripp
Selective cyclooxygenase-2 inhibition does not alter keratinocyte wound responses in the mouse epidermis after abrasion.
The Journal of pharmacology and experimental therapeutics 2003;304(3):959-67.
2003: Krista M D La Perle; Eric A G Blomme; Charles C Capen; Sissy M Jhiang
Effect of exogenous human sodium iodide symporter expression on growth of MATLyLu cells.
Thyroid : official journal of the American Thyroid Association 2003;13(2):133-40.
2003: Eric A G Blomme; Kevin S Chinn; Medora M Hardy; J J Casler; S H Kim; Alan Opsahl; W A Hall; D Trajkovic; Tariq Khan; Catherine S Tripp
Selective cyclooxygenase-2 inhibition does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice.
The British journal of dermatology 2003;148(2):211-23.
2003: W Rachel Duan; Debra S Garner; Steven D Williams; Christie L Funckes-Shippy; Iwona S Spath; Eric A G Blomme
Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts.
The Journal of pathology 2003;199(2):221-8.
2002: Krista M D La Perle; Eric A G Blomme; John E Sagartz; Charles C Capen
Epididymal cribriform hyperplasia with nuclear atypia in p53 homozygous knockout mice on a mixed 129/Sv-FVB/N background.
Comparative medicine 2002;52(6):568-71.
2002: Ricardo Rocha; Amy E Rudolph; Gregory E Frierdich; Denise A Nachowiak; Beverly K Kekec; Eric A G Blomme; Ellen G McMahon; John A Delyani
Aldosterone induces a vascular inflammatory phenotype in the rat heart.
American journal of physiology. Heart and circulatory physiology 2002;283(5):H1802-10.
2001: Rani S Sellers; Ramiro E Toribio; Eric A G Blomme
Idiopathic systemic granulomatous disease and macrophage expression of PTHrP in a miniature pony.
Journal of comparative pathology 2001;125(2-3):214-8.
2001: Andrew Lisowski; M L English; Alan Opsahl; Roderick T Bunch; Eric A G Blomme
Effect of the storage period of paraffin sections on the detection of mRNAs by in situ hybridization.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(7):927-8.
1999: KM Dougherty; Eric A G Blomme; Amy J Koh; J E Henderson; Kenneth J Pienta; Thomas J Rosol; Laurie K McCauley
Parathyroid hormone-related protein as a growth regulator of prostate carcinoma.
Cancer research 1999;59(23):6015-22.
1999: Krista M D La Perle; F Silveria; David E Anderson; Eric A G Blomme
Dalmeny disease in an alpaca (Lama pacos): sarcocystosis, eosinophilic myositis and abortion.
Journal of comparative pathology 1999;121(3):287-93.
1999: Eric A G Blomme; Sugimoto Yasuro; Young C Lin; Charles C Capen; Thomas J Rosol
Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts.
Molecular and cellular endocrinology 1999;152(1-2):189-97.
1999: Eric A G Blomme; KM Dougherty; Kenneth J Pienta; Charles C Capen; Thomas J Rosol; Laurie K McCauley
Skeletal metastasis of prostate adenocarcinoma in rats: morphometric analysis and role of parathyroid hormone-related protein.
The Prostate 1999;39(3):187-97.
1999: Eric A G Blomme; H Zhou; V Kartsogiannis; Charles C Capen; Thomas J Rosol
Spatial and temporal expression of parathyroid hormone-related protein during wound healing.
The Journal of investigative dermatology 1999;112(5):788-95.
1999: Eric A G Blomme; S H Foy; K H Chappell; Krista M D La Perle
Hypereosinophilic syndrome with Hodgkin's-like lymphoma in a ferret.
Journal of comparative pathology 1999;120(2):211-7.
1998: Krista M D La Perle; Raymond F Wack; L Kaufman; Eric A G Blomme
Systemic candidiasis in a cheetah (Acinonyx jubatus).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 1998;29(4):479-83.
1998: A Gröne; MT Weckmann; Eric A G Blomme; Charles C Capen; Thomas J Rosol
Dependence of humoral hypercalcemia of malignancy on parathyroid hormone-related protein expression in the canine anal sac apocrine gland adenocarcinoma (CAC-8) nude mouse model.
Veterinary pathology 1998;35(5):344-51.
1998: Eric A G Blomme; Sugimoto Yasuro; Laurie K McCauley; Young C Lin; Charles C Capen; Thomas J Rosol
Stromal and epithelial cells of the canine prostate express parathyroid hormone-related protein, but not the PTH/PTHrP receptor.
The Prostate 1998;36(2):110-20.
1998: J R Werkmeister; Eric A G Blomme; MT Weckmann; A Gröne; Laurie K McCauley; A B Wade; J O'Rourke; Charles C Capen; Thomas J Rosol
Effect of transforming growth factor-beta1 on parathyroid hormone-related protein secretion and mRNA expression by normal human keratinocytes in vitro.
Endocrine 1998;8(3):291-9.
1998: Eric A G Blomme; J R Werkmeister; H Zhou; V Kartsogiannis; Charles C Capen; Thomas J Rosol
Parathyroid hormone-related protein expression and secretion in a skin organotypic culture system.
Endocrine 1998;8(2):143-51.
1998: Krista M D La Perle; Richard J Piercy; John F Long; Eric A G Blomme
Multisystemic, eosinophilic, epitheliotropic disease with intestinal lymphosarcoma in a horse.
Veterinary pathology 1998;35(2):144-6.
1998: Eric A G Blomme; MT Weckmann; Charles C Capen; Thomas J Rosol
Influence of extracellular matrix macromolecules on normal human keratinocyte phenotype and parathyroid hormone-related protein secretion and expression in vitro.
Experimental cell research 1998;238(1):204-15.