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Xu-Bao Shi

Research Profile

Disorders

Genes & Molecular Sequences

Genes, p53

Chemicals & Drugs

Anatomy

Physiology

Living Beings

Procedures

Devices

Oligonucleotide Array Sequence Analysis

Phenomena

Blotting, Western

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Publications

TOP 3
Chengfei Liu; Wei Lou; Nagalakshmi Nadiminty; Xu-Bao Shi; Qinghua Zhou; Yezi Zhu; Xinbin Chen; Ralph W deVere White; Allen C Gao
Functional p53 determines docetaxel sensitivity in prostate cancer cells.
Sumaira Amir; Hsing-Jien Kung; Ai-Hong Ma; Xu-Bao Shi; Lingru Xue; Ralph W deVere White
Oncomir miR-125b Suppresses p14(ARF) to Modulate p53-Dependent and p53-Independent Apoptosis in Prostate Cancer.
Nagalakshmi Nadiminty; Xu-Bao Shi; Ramakumar Tummala; Jin Zhang; Yezi Zhu; June X Zou; Hongwu Chen; Xinbin Chen; Ralph W deVere White; Christopher P Evans; Hsing-Jien Kung; Wei Lou; Jun Luo; Allen C Gao
MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth.

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All Publications

2013: Chengfei Liu; Wei Lou; Nagalakshmi Nadiminty; Xu-Bao Shi; Qinghua Zhou; Yezi Zhu; Xinbin Chen; Ralph W deVere White; Allen C Gao
Functional p53 determines docetaxel sensitivity in prostate cancer cells.
The Prostate 2013;73(4):418-27.
2013: Sumaira Amir; Hsing-Jien Kung; Ai-Hong Ma; Xu-Bao Shi; Lingru Xue; Ralph W deVere White
Oncomir miR-125b Suppresses p14(ARF) to Modulate p53-Dependent and p53-Independent Apoptosis in Prostate Cancer.
PloS one 2013;8(4):e61064.
2012: Nagalakshmi Nadiminty; Xu-Bao Shi; Ramakumar Tummala; Jin Zhang; Yezi Zhu; June X Zou; Hongwu Chen; Xinbin Chen; Ralph W deVere White; Christopher P Evans; Hsing-Jien Kung; Wei Lou; Jun Luo; Allen C Gao
MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth.
PloS one 2012;7(3):e32832.
2011: Baoqing Li; Xu-Bao Shi; Dattatreyudu Nori; K.S. Chao; Allen M Chen; Richard Valicenti; Ralph W deVere White
Down-regulation of microRNA 106b is involved in p21-mediated cell cycle arrest in response to radiation in prostate cancer cells.
The Prostate 2011;71(6):567-74.
2011: Xu-Bao Shi; Lingru Xue; Donghua Shi; Ralph W deVere White
Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor.
Cancer biotherapy & radiopharmaceuticals 2011;26(2):191-201.
2011: Xu-Bao Shi; Lingru Xue; Ai-Hong Ma; Clifford G Tepper; Hsing-Jien Kung; Ralph W deVere White
miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes.
The Prostate 2011;71(5):538-49.
2009: Ralph W deVere White; Ruth L Vinall; Clifford G Tepper; Xu-Bao Shi
MicroRNAs and their potential for translation in prostate cancer.
Urologic oncology 2009;27(3):307-11.
2008: Xu-Bao Shi; Lingru Xue; June X Zou; Regina Gandour-Edwards; Hongwu Chen; Ralph W deVere White
Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells.
The Prostate 2008;68(16):1816-26.
2008: Xu-Bao Shi; Clifford G Tepper; Ralph W deVere White
MicroRNAs and prostate cancer.
Journal of cellular and molecular medicine 2008;12(5A):1456-65.
2008: Xu-Bao Shi; Clifford G Tepper; Ralph W deVere White
Cancerous miRNAs and their regulation.
Cell cycle (Georgetown, Tex.) 2008;7(11):1529-38.
2008: S Liu; Ruth L Vinall; Clifford G Tepper; Xu-Bao Shi; L R Xue; Ai-Hong Ma; L-Y Wang; L D Fitzgerald; Z Wu; Regina Gandour-Edwards; Ralph W deVere White; Hsing-Jien Kung
Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway.
Oncogene 2008;27(4):499-505.
2007: Xu-Bao Shi; Lingru Xue; Joy Yang; Ai-Hong Ma; Jian-Jun Zhao; Ma Xu; Clifford G Tepper; Christopher P Evans; Hsing-Jien Kung; Ralph W deVere White
An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19983-8.
2007: Xu-Bao Shi; Lingru Xue; Clifford G Tepper; Regina Gandour-Edwards; Paramita M Ghosh; Hsing-Jien Kung; Ralph W deVere White
The oncogenic potential of a prostate cancer-derived androgen receptor mutant.
The Prostate 2007;67(6):591-602.
2007: Clifford G Tepper; Ruth L Vinall; Christopher B Wee; Lingru Xue; Xu-Bao Shi; Rebekah Burich; Philip C Mack; Ralph W deVere White
GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms.
The Prostate 2007;67(5):521-35.
2006: June X Zou; Zhenyu Zhong; Xu-Bao Shi; Clifford G Tepper; Ralph W deVere White; Hsing-Jien Kung; Hongwu Chen
ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes.
The Prostate 2006;66(14):1474-86.
2006: Ai-Hong Ma; Liang Xia; Sonal J Desai; David Boucher; Yi Guan; Hsiu-Ming Shih; Xu-Bao Shi; Ralph W deVere White; Hongwu Chen; Clifford G Tepper; Hsing-Jien Kung
Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells.
Cancer research 2006;66(17):8439-47.
2006: Cheng-Yi Xiong; Arutselvan Natarajan; Xu-Bao Shi; Gerald L DeNardo; Sally J DeNardo
Development of tumor targeting anti-MUC-1 multimer: effects of di-scFv unpaired cysteine location on PEGylation and tumor binding.
Protein engineering, design & selection : PEDS 2006;19(8):359-67.
2006: Ruth L Vinall; Clifford G Tepper; Xu-Bao Shi; L A Xue; Regina Gandour-Edwards; Ralph W deVere White
The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7.
Oncogene 2006;25(14):2082-93.
2006: Zongbing You; Xu-Bao Shi; Grayson DuRaine; Dominik R Haudenschild; Clifford G Tepper; Su Hao Lo; Regina Gandour-Edwards; Ralph W deVere White; Hari Reddi
Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer.
Cancer research 2006;66(1):175-83.
2005: Clifford G Tepper; Jeffrey P Gregg; Xu-Bao Shi; Ruth L Vinall; Colin A Baron; Philip E Ryan; Pierre-Yves Desprez; Hsing-Jien Kung; Ralph W deVere White
Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells.
The Prostate 2005;65(4):375-89.
2005: Javid Javidan; Arline D Deitch; Xu-Bao Shi; Ralph W deVere White
The androgen receptor and mechanisms for androgen independence in prostate cancer.
Cancer investigation 2005;23(6):520-8.
2004: Xu-Bao Shi; Regina Gandour-Edwards; Laurel Beckett; Arline D Deitch; Ralph W deVere White
A modified yeast assay used on archival samples of localized prostate cancer tissue improves the detection of p53 abnormalities and increases their predictive value.
BJU international 2004;94(7):996-1002.
2004: Xu-Bao Shi; Ai-Hong Ma; Clifford G Tepper; Liang Xia; Jeffrey P Gregg; Regina Gandour-Edwards; Philip C Mack; Hsing-Jien Kung; Ralph W deVere White
Molecular alterations associated with LNCaP cell progression to androgen independence.
The Prostate 2004;60(3):257-71.
2003: Nancy J Nesslinger; Xu-Bao Shi; Ralph W deVere White
Androgen-independent growth of LNCaP prostate cancer cells is mediated by gain-of-function mutant p53.
Cancer research 2003;63(9):2228-33.
2002: Xu-Bao Shi; Stephen M Di Mauro; Ralph A Highshaw; Arline D Deitch; Christopher P Evans; Paul H Gumerlock; Ralph W deVere White
Application of a yeast assay to detect functional p53 mutations in archival prostate cancer tissue.
Cancer biotherapy & radiopharmaceuticals 2002;17(6):657-64.
2002: Susan L Scott; Roger Higdon; Laurel Beckett; Xu-Bao Shi; Ralph W deVere White; John D Earle; Paul H Gumerlock
BCL2 antisense reduces prostate cancer cell survival following irradiation.
Cancer biotherapy & radiopharmaceuticals 2002;17(6):647-56.
2002: Xu-Bao Shi; Nancy J Nesslinger; Arline D Deitch; Paul H Gumerlock; Ralph W deVere White
Complex functions of mutant p53 alleles from human prostate cancer.
The Prostate 2002;51(1):59-72.
2002: Xu-Bao Shi; Ai-Hong Ma; Liang Xia; Hsing-Jien Kung; Ralph W deVere White
Functional analysis of 44 mutant androgen receptors from human prostate cancer.
Cancer research 2002;62(5):1496-502.
2001: DG DeNardo; Cheng-Yi Xiong; Xu-Bao Shi; Gerald L DeNardo; Sally J DeNardo
Anti-HLA-DR/anti-DOTA diabody construction in a modular gene design platform: bispecific antibodies for pretargeted radioimmunotherapy.
Cancer biotherapy & radiopharmaceuticals 2001;16(6):525-35.
2001: Xu-Bao Shi; Paul H Gumerlock; JT Muenzer; Ralph W deVere White
BCL2 antisense transcripts decrease intracellular Bcl2 expression and sensitize LNCaP prostate cancer cells to apoptosis-inducing agents.
Cancer biotherapy & radiopharmaceuticals 2001;16(5):421-9.
2001: Linda A Kroger; Gerald L DeNardo; Paul H Gumerlock; Cheng-Yi Xiong; Michelle D Winthrop; Xu-Bao Shi; Philip C Mack; T Leshchinsky; Sally J DeNardo
Apoptosis-related gene and protein expression in human lymphoma xenografts (Raji) after low dose rate radiation using 67Cu-2IT-BAT-Lym-1 radioimmunotherapy.
Cancer biotherapy & radiopharmaceuticals 2001;16(3):213-25.
2000: A A TenHave-Opbroek; Xu-Bao Shi; Paul H Gumerlock
3-Methylcholanthrene triggers the differentiation of alveolar tumor cells from canine bronchial basal cells and an altered p53 gene promotes their clonal expansion.
Carcinogenesis 2000;21(8):1477-84.
1999: Sally J DeNardo; Gerald L DeNardo; DG DeNardo; Cheng-Yi Xiong; Xu-Bao Shi; Michelle D Winthrop; Linda A Kroger; P Carter
Antibody phage libraries for the next generation of tumor targeting radioimmunotherapeutics.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3213s-3218s.
1999: Ralph W deVere White; Arline D Deitch; Paul H Gumerlock; Xu-Bao Shi
Use of a yeast assay to detect functional alterations in p53 in prostate cancer: review and future directions.
The Prostate 1999;41(2):134-42.
1999: Xu-Bao Shi; Paul H Gumerlock; Linda A Kroger; Gerald L DeNardo; Sally J DeNardo
Efficient recombination of Lym-1 scFv gene using multiple doubly-restricted DNA fragments.
Cancer biotherapy & radiopharmaceuticals 1999;14(2):139-43.
1998: Robert T O'Donnell; Sally J DeNardo; Xu-Bao Shi; Gary R Mirick; Gerald L DeNardo; Linda A Kroger; Frederick J Meyers
L6 monoclonal antibody binds prostate cancer.
The Prostate 1998;37(2):91-7.
1997: Paul H Gumerlock; SG Chi; Xu-Bao Shi; H James Voeller; J W Jacobson; Edward P Gelmann; Ralph W deVere White
p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network.
Journal of the National Cancer Institute 1997;89(1):66-71.
1996: Xu-Bao Shi; S M Bodner; Ralph W deVere White; Paul H Gumerlock
Identification of p53 mutations in archival prostate tumors. Sensitivity of an optimized single-strand conformational polymorphism (SSCP) assay.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1996;5(4):271-8.
1996: Xu-Bao Shi; Paul H Gumerlock; Ralph W deVere White
Molecular biology of prostate cancer.
World journal of urology 1996;14(5):318-28.
1993: Xu-Bao Shi; Paul H Gumerlock; A A Wellman; Claude F Meares; Gerald L DeNardo; Frederick J Meyers; Sally J DeNardo
Rapid PCR construction of a gene containing Lym-1 antibody variable regions.
PCR methods and applications 1993;3(1):46-53.